Symposium Program
Monday 23. 9. 2024
13:00-18:00

Registration in the Smolenice Castle

14:00

Bus departure from Bratislava to Smolenice

18:10-18:15

Opening ceremony
Jaroslav Katrlík, Stanislav Kozmon
Section 1 (Chair: Carme Rovira)

18:15-18:55

PL1

19:00

Celso Reis (University of Porto, Porto, Portugal)
THE DIVERSITY AND FUNCTIONALITY OF THE
CANCER GLYCOME: ROLE IN ONCOGENICPROCESSES TO CLINICAL IMPLICATIONS

Welcome dinner

Tuesday 24. 9. 2024
7:30-9:00

Breakfast

Section 2 (Chair: Celso Reis)
9:00-9:40

PL2Christophe Len (CNRS, Paris, France)
A TOUR AROUND THE GREEN CONTINUOUS FLOWSYNTHESIS OF FURAN DERIVATIVES FROMCELLULOSIC BIOMASS

9:40-10:00

OP1Alexei V. Demchenko (University of St. Louis, St. Louis,USA)
FROM STEREOCONTROLLED GLYCOSYLATION TO
AUTOMATED CHEMICAL SYNTHESIS OF
CARBOHYDRATES

10:00-10:20

OP2

10:20-10:40

Marlene C.S. Dal Colle (Max Plank Institute, Potsdam,Germany)
RATIONALLY DESIGNED MUCIN-LIKE GLYCOHYDROGELS

Coffee BreakSection 3 (Chair: M. Rita Ventura)
10:40-11:10

IL1Anikó Borbás (University of Debrecen, Debrecen, Hungary)
STEREOSELECTIVE SYNTHESIS OF TREHALOSETYPE α, α -THIODISACCHARIDES USING THIOL-ENE
PHOTOCLICK CHEMISTRY

11:10-11:30

OP3Mihály Herczeg (University of Debrecen, Debrecen,Hungary)
SYNTHESIS AND BIOLOGICAL PROFILING OFSEVEN D-GLUCURONIC ACID CONTAINING
HEPARINOID TRISACCHARIDES

11:30-11:50

OP4Alla Zamyatina (BOKU, Vienna, Austria)
SYNTHETIC DISACCHARIDE-BASED PICOMOLAR
TLR4 AGONISTS AS POTENTIALIMMUNOTHERAPEUTICS: THE STRUCTURAL BASIS

11:50-12:00

ELICITYL (commercial lecture)

12:00-14:00

Lunch

Section 4 (Chair: Christophe Len)
14:00-14:40

PL3Bernd Nidetzky (Graz University of Technology, Graz,Austria)
ENZYMOLOGY OF MICROBIAL METABOLISM OF
C-GLYCOSYL COMPOUNDS

14:40-15:00

OP5Peter Gabko (Slovak Academy of Sciences, Bratislava,Slovakia)
TURNING RIBOSE INTO ALKALOIDS:STEREOSELECTIVE SYNTHESIS OF 5-SUBSTITUTED
1,2-DIHYDROXYINDOLIZIDINES AND –PYRROLIZIDINES

15:00-15:10

FP1Erika Mezö (University of Debrecen, Debrecen, Hungary)
SYNTHESIS OF IMINOSUGAR ANALOGS WITH
MORPHOLINE AND OXAZEPANE BACKBONE

15:10-15:30

Coffee BreakSection 5 (Chair: Lara Mahal)
15:30-16:00

IL2M. Rita Ventura (Universidade Nova de Lisboa, Lisboa,Portugal)
A NOVEL FUNCTIONAL ASSAY FOR THE STUDY OF
NEW DRUG TARGETS IN MYCOBACTERIA

16:00-16:20

OP6Juan Uribe-Gomez (University of Galway, Galway, Ireland)
LINEAR SUGAR-ENDING POLYETHYLENE GLYCOL:A POTENTIAL MATERIAL FOR NEXT-GENERATIONIMPLANTS

16:20-16:40

OP7Gavin J. Miller (Keele University, Keele, UK)SWEETTARGETS:THE
SEARCHFOR
GLYCOCONJUGATE PROBES AND INHIBITORS OFGDPMANNOSE
DEHYDROGENASEFROMPSEUDOMONAS AERUGINOSA

16:40-16:50

FP2Adria Alcaide Jimenez (IMBM-CSIC, Barcelona, Spain)
ENZYMATIC INITIATION AND POLYMERIZATIONOF GROUP 2 BACTERIAL CAPSULES

17:00-18:45

Poster Session

19:00

DinnerWednesday 25. 9. 2024
7:30-9:00

Breakfast
Section 6 (Chair: Bernd Nidetzky)

9:00-9:40

PL4

Carme Rovira (ICREA, Barcelona, Spain)
NON-CLASSICAL GLYCOSYLATION REACTIONMECHANISMS: A MODELING APPROACH

9:40-10:00

OP8Robert J. Woods (University of Georgia, Athens, USA)
AUTOMATING THE DESIGN OF GLYCOMIMETICAGENTS

10:00-10:20

OP9Stanislav Kozmon (Slovak Academy of Sciences, Bratislava,Slovakia)
IN SILICO AND EXPERIMENTAL STUDY OF THE
XYLOGLUCAN ENDOTRANSGLYCOSYLASE (XET)
INTERACTIONS

10:20-10:30

FP3Jan Beránek (University of Chemistry and Technology,Prague, Czechia)
USING ALCHEMICAL FREE ENERGYCALCULATIONS TO PREDICT PROTEINSACCHARIDE RELATIVE BINDING AFFINITY

10:30-10:50

Coffee BreakSection 7 (Chair: Anikó Borbás)
10:50-11:20

IL3Cristina Airoldi (University of Milano-Bicocca, Milano,Italy)
NMR TOOLS FOR THE IDENTIFICATION AND
DEVELOPMENT OF CARBOHYDRATE-BASEDBIOACTIVE COMPOUNDS

11:20-11:40

OP10 Martin Kurfiřt (Czech Academy of Sciences, Prague,Czechia)
FLUORINE-INDUCED STRENGTHENING OF C‒H/πINTERACTION AS AN IMPORTANT DRIVING FORCEBEHIND THE RECOGNITION OF FLUORINATEDDISACHARIDES BY WHEAT GERM AGGLUTININE

11:40-12:00

OP11 Marko Anderluh (University of Ljubljana, Ljubljana,Slovenia)
FIRST-IN-CLASS NANOMOLAR INHIBITORS OF
GALECTIN-8 N-TERMINAL DOMAIN BIND VIA NONCANONICAL CATION-π INTERACTIONS

12:00-12:10

FP4Jindřich Karban (Czech Academy of Sciences, Prague,Czechia)
FERROCENE-MODIFIED DISACCHARIDES ASGALECTIN INHIBITORS

12:10-12:20FP5Michal Hricovíni (Slovak Academy of Sciences, Bratislava,Slovakia)
NMR AND DFT ANALYSIS OF PHOTOCHEMICALLYINDUCED PROCESS IN GLUCOSE-BASEDGLYCOCONJUGATE

12:20-14:00

Lunch

14:30-22:00

Half day trip + Social dinnerThursday 26. 9. 2024
7:30-9:00

Breakfast
Section 8 (Chair: Iain B.H. Wilson)

9:00-9:40

PL5Lara Mahal (University of Alberta, Edmonton, Canada)
ADDING A LITTLE SUGAR: INTEGRATINGGLYCOMICS INTO MULTI’OMIC ANALYSIS BRINGSNEW INSIGHTS

9:40-10:00

OP12 Stefan Mereiter (Austrian Academy of Sciences, Vienna,Austria)
TUMOR SIALYLATION CONTROLS EFFECTIVE
ANTI-CANCER IMMUNITY IN BREAST CANCER

10:00-10:20

OP13Natália Košútová (Slovak Academy of Sciences, Bratislava,Slovakia)
EXOSOMES AS POTENTIAL PROSTATE CANCER
BIOMARKERS FOR THE LIQUID BIOPSY TESTING

10:20-10:40

FP6

Andrea Pinkeová (Glycanostics, Bratislava, Slovakia)
THE POTENTIAL OF LECTIN-LINKEDIMMUNOSORBENT ASSAYS IN GLYCAN-BASEDDIAGNOSTICS OF ONCOLOGICAL DISEASES

10:40-11:00

Coffee BreakSection 9 (Chair: Daniel Bojar)
11:00-11:30

IL4Vered Padler-Karavani (Tel Aviv University, Tel Aviv,Israel)
IMMUNOTHERAPY TARGETING CANCERGLYCOSYLATION

11:30-12:00

IL5Zuzana Pakanová (Slovak Academy of Sciences, Bratislava,Slovakia)
MASS SPECTROMETRY ANALYSIS OFGLYCOCONJUGATES IN DIAGNOSTICS AND
BIOMARKER DISCOVERY

12:00-12:10

FP7Paula Peinsipp (University of Graz, Graz, Austria)
ALTERNATIVES TO ACYCLOVIR TO COMBAT HSV-1
INFECTION

12:10-12:20

FP8Elisa Talker (University of Graz, Graz, Austria)
PHAGE DISPLAY-DERIVED VNARS (VARIABLE NEWANTIGEN RECEPTORS) AGAINST A WELL-DEFINEDGLYCOSAMINOGLYCAN STRUCTURE

12:20-14:00

LunchSection 10 (Chair: Zuzana Pakanová)
14:00-14:30

IL6

14:30-14:50

OP14 Katharina Paschinger (BOKU, Vienna, Austria)
MALDI-TOF MS AS A TOOL FOR MARINE
GLYCOMICS

14:50-15:10

OP15 Alba Hykollari (BOKU, Vienna, Austria)
NEW INSIGHTS INTO THE N-GLYCOME FROM THE
INVERTEBRATE DICTYOSTELIUM SPECIES

15:10-15:20

FP915:20-15:40

Iain B.H. Wilson (BOKU, Vienna, Austria)
INVERTEBRATE N-GLYCOSYLATION STRUCTURES & INTERACTIONSFriedrich Altmann (BOKU, Vienna, Austria)
GREEN ALGAE – THE MASTERS OF GLYCODIVERSITY

Coffee BreakSection 11 (Chair: Vered Padler-Karavani)
15:40-16:10

IL7

16:10-16:30

OP16 Ran Xie (Nanjing University, Nanjing, China)
PAN-SCALE MULTIDISCIPLINARY STUDIES OF
GLYCANS

16:30-16:40

FP10

17:15

Daniel Bojar (University of Gothenburg, Gothenburg,Sweden)
WHITE GOLD – DISCOVERING AND ANALYZINGNEW MILK OLIGOSACCHARIDES

Jon Lundstrøm (University of Gothenburg, Gothenburg,Sweden)
ELUCIDATING THE GLYCAN-BINDING SPECIFICITY
AND STRUCTURE OF CUCUMIS MELOAGGLUTININ, A NEW R-TYPE LECTIN

Farewell party including poster award

Friday 27. 9. 2024
8:00-9:30

Breakfast

Section 12 (Chair: Cristina Airoldi)
10:00-10:20

OP17 Maroš Krchňák (Slovak Academy of Sciences, Bratislava,Slovakia)
COMPARISON AND APPLICATIONS OF LC-MSWORKFLOWS IN N-GLYCOMICS

10:20-10:30

FP11Juvissan Medalith Aguedo Ariza (Slovak Academy ofSciences, Bratislava, Slovakia)
GLYCOBIOMARKER DISCOVERY FOR
COLORECTAL CANCER DIAGNOSIS

10:30-10:40

FP12Paras Kundalia (Slovak Academy of Sciences, Bratislava,Slovakia)
A HOLISTIC APPROACH TO OPTIMIZE FACTORSCONTRIBUTING TO VARIABILITY IN
GLYCOPROTEIN MICROARRAY ANALYSIS

10:40-10:45

Closing ceremony
Jaroslav Katrlík, Stanislav Kozmon

11:00-11:45

Lunch

12:00

Bus departure to Bratislava