Chapter 1

The Patient Interview
Sneha Baxi Srivastava, PharmD, BCACP

Learning Objectives• Explain the basic communication skills needed when performing a patient interview.
• Describe the components of the patient interview.
• Conduct a thorough medication history.
• Compare and contrast the different patient interview approaches in various clinical settings.
• Adapt the interview technique based on the needs of the patient.

Key Terms• Active Listening• Rapport• Empathy• Open-Ended Questions• Leading Questions• Probing Questions• Nonverbal Communication• Chief Complaint• History of Present Illness• Pertinent Positive• Pertinent Negative• Past History• Medication History• Family History• Personal and Social History• Review of Systems• Physical Exam
• QuEST/SCHOLAR-MAC

Introduction
The patient interview is the primary way of obtaining comprehensive information
about the patient in order to provide effective patient-centered care, and the medication history component is the pharmacist’s expertise. A methodological approach isused to obtain information from the patient, usually starting with determining thepatient’s chief complaint, also known as the reason for the healthcare visit, and then2  	

Chapter 1 / The Patient Interview

delving further into an exploration of the patient’s specific complaint and problem.
A comprehensive patient interview includes inquiring about the patient’s medical,
medication, social, personal, and family history, as well as a thorough review of systems
and possibly a physical examination.
The medication history is the part of the patient interview that provides thepharmacist the opportunity to utilize his or her expertise by precisely collecting
each component of the medication history (however, a medication history may also
be collected independent of a comprehensive patient interview). The questions
that you ask the patient, as well as the technique used, will enable you to learn
exactly how, when, and why a patient takes each medication, as well as about any
adverse reactions, allergies, or issues with medication cost the patient may haveexperienced.
The approach to the patient interview and medication history will change basedon the setting in which you are practicing. For example, if the setting is a community
pharmacy and you are responding to a problem that may allow for self-care, yourquestions will be directed at meticulously characterizing the patient’s complaint andobtaining specific information that will influence your assessment and plan for thepatient. However, if you are in a hospital, the focus of the interview may need to bemodified based on the patient’s condition and the particular unit or department inwhich he or she is being cared for so that the patient’s needs may be met.
Regardless of the setting, your goal during the interview will be to provide
patient-centered care; this can be accomplished by combining your pharmacotherapeutic knowledge with a solid foundation of excellent communication andpatient-interviewing skills. Excelling in these communication skills is a learned
technique that takes time and practice to master. Once these skills are employed in­practice, the relationship that is developed with the patient is often stronger,­allowing for the patient to have increased confidence and trust in your role asa healthcare provider.
The purpose of this chapter is to describe the various components of the comprehensive health history and to provide an overview of the skills and techniques required
when communicating with the patient. This chapter will focus on the best practices tofollow when collecting information from the patient.

Communication Skills
Communication skills are the fundamental link between the pharmacist’s expertise
about drugs and his or her contribution to providing excellent patient-centered care.
Although communicating with a patient may seem like a simple task, it actually takes

Communication Skills

practice and knowledge to communicate with the patient in a manner that encourages respect for the healthcare provider and that enables the pharmacist to obtainan accurate and complete history. Some practitioners are able to naturally communicate with patients more effectively, whereas others have difficulty communicating with patients due to a variety of reasons, including their personality, comfort
level, and confidence. However, regardless of one’s natural abilities, communication skills and questioning techniques, especially when it comes to communicatingwith patients, are learned and take time to develop. A variety of excellent in-depth
resources describe communication skills. This chapter examines the most pertinentskills required to conduct a comprehensive medication history. These skills andquestioning techniques include:• Active listening• Empathy• Building rapport• Open-ended questions• Closed-ended questions• Leading questions• Silence• “Why” questions• Nonverbal communication cues

Active Listening
The first communication skill to be mastered is listening, specifically active listening. Listening is defined as hearing what is being said, whereas active listening is a
dynamic process that includes both hearing what is being said as well as processing
and interpreting the words that are spoken (and/or unspoken) to understand thecomplete message that is being delivered. Whereas listening is a passive process,active listening requires the listener to consciously choose to give the patient attention and concentration that is free of distractions and interruptions, both external
and internal.
External distractions are the easier of the two to avoid. External distractions
include ringing telephones, flickering computer screens, and other infringing personal and/or other duties. These external distractions can be avoided by interactingwith your patient in a place that is free of such distractions.
Internal distractions occur for two major reasons: (1) many matters, unrelated to the patient in front of you, may occupy your mind and (2) it is difficult

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to perceive what the patient is saying without tainting his or her message withyour personal judgment. The first reason can be addressed by making a conscious
effort to concentrate solely on your interaction with the patient. This is more difficult to accomplish than it sounds, but, with practice, turning on the “listening
switch” in your mind will become easier.1 The second reason is more difficult toaddress, because instinct often leads us to judge or evaluate what the patient issaying based on our own frame of reference. Biases, prejudices, and judgments
cloud the message that is being delivered by the patient, which, in turn, affect thepatient interaction, and possibly clinical outcomes.2 For example, as you prepare
for a patient who has been referred to you for smoking cessation counseling, youread in several progress notes that the patient “refuses to give up smoking.” As
you meet with that patient, in your mind you may be thinking that “it’s so difficult
to give up smoking and most people don’t really want to give up smoking” basedon your previous encounters with other patients. After reading the patient’s notes,
your preconception may be strengthened. Therefore, as your patient is talking
about reasons why it is difficult for him to quit smoking, your mind is hearing
what is being said but is interpreting it as excuses rather than reasons that you may
be able to address with the patient to assist him in quitting smoking. One way to
overcome internal distractions is by being present in the moment, during yourpatient visit, addressing your patient’s current concerns without focusing on yourpreconceived notions.

Empathy
Empathy is defined as the “intellectual identification with or vicarious experiencing of
the feelings, thoughts, or attitudes of another.”3 The terms empathy and sympathy areoften confused. Sympathy is when you feel sorry for the patient but do not feel the same
emotions or are not in the same situation, whereas empathy is when you place yourself
in your patient’s situation and respond based on either similar personal experiences or
through vicarious understanding. When you express empathy, it allows your patient tofeel as though you understand his or her unique experience and that you are applying
your expertise to the patient as an individual.
Empathy can be shown in several ways, and each way will depend upon the particular patient as well as the situation. For example, nodding your head, making a statement, or asking a follow-up question can show empathy.2 Additionally, it is important
to distinguish between an empathetic statement and the assumption that you know
exactly what the patient is feeling. For example, saying to your patient who has been

Communication Skills

diagnosed with cancer, “I know just how you are feeling. My grandfather had cancer
and it was such a shock to all of us. At first, he was just so overwhelmed and upset”
may make the patient feel like you are not truly listening to her, but rather assumingthat she will respond like anyone else with a cancer diagnosis. It may be better to say,
“I know from some personal experiences that finding out about cancer can be very
overwhelming. How are you feeling?” Although there is no one way to show empathy,
focusing on the key factors of allowing patients to feel understood while maintaining
the uniqueness of their experience(s) may allow for a better patient interaction.

Building Rapport
The first impression you make on your patient will weigh on the rest of the patientinterview as well as affect your relationship with the patient. Building a good ­rapport
sets the tone for the interview and allows the patient to feel comfortable with you,thereby making the lines of communication more open and honest. Patients may
sometimes withhold information if they feel uncomfortable or anxious about sharing
their complaints because of a lack of feeling respected, feeling as though their words
are not being heard, or quite simply not knowing who you are and what your role is in
their care. Therefore, starting the interview by greeting the patient by name, making
sure you are pronouncing the patient’s name correctly, asking how he or she prefers
to be addressed, and adding a title to his or her name, if preferred, will indicate yourinterest in the patient and show that you care. You should also give your name andtitle and then briefly describe the purpose of the interview. For example, you could
say, “Hello Mrs. Smith, my name is Ankur Kumar. I am the pharmacist who is part ofyour medical team, and I am here to ask you a few questions about what brought you
to the hospital and discuss the medications you have been taking at home.” If there
are others in the room, you should greet each person in the room, and then ask yourpatient for permission to continue with the interview in the presence of others. For
example, you may say, “I have a few questions for you, Mrs. Smith. Is it okay for me
to speak to you with your family/friends in the room or would you prefer to be alone
while we talk?”
Even if you have met the patient before, you may want to remind the patient of
your role, especially if you are in a hospital setting where the patient may be overwhelmed by the many providers participating in his or her care.4 Making appropriate introductions, interacting respectfully with the patient, and making the patient
feel comfortable will build excellent rapport, leading to a strong foundation for thepatient–pharmacist relationship.

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Open- and Closed-Ended Questions
Open-ended questions are questions that require the patient to answer with morethan a simple yes or no or nod of the head, whereas closed-ended questions generally limit the patient’s response to either a yes or no or a nod of the head. In general,
open-ended questioning is the preferred technique to use during patient interviews tocompel the patient to provide more in-depth and insightful responses. Because openended questions do not limit the patient to responding with a yes or no, they encourage the patient to disclose more information. For example, you can start the interview
by asking an open-ended question, such as “How are you feeling today?” or a closedended question, such as “Are you feeling well today?” The first approach allows for thepatient to answer in free form and possibly give you more detail about the conditionof his or her health, whereas the second way leads the patient to answer with either ayes or no, thereby limiting the information that you obtain from the patient.2 This, inturn, may lead to a rapid sequence of more closed-ended questions.
For example, if you ask the patient a closed-ended question such as, “Do you
take your medications as directed by your physician?” you will most likely receivea response of “yes.” Although the patient may indeed be taking each medication as
directed by his or her physician, you may be missing the opportunity to discover how
the patient is actually taking each medication. Instead, if you ask the patient an openended question, such as “How are you taking this medication?” the answer will likely
include more details, such as the dose and frequency of the medication. By gathering
more information with open-ended questioning, you may learn that there are discrepancies between how the patient is actually taking the medication and how it has
been prescribed. Oftentimes, a patient answers, “Yes, I am taking it as directed,” but
you then discover that this is not the case, perhaps as a result of dishonesty but more
likely because the patient believes that he or she is taking the medication correctly.
The use of open-ended questions enables you to gather more information from thepatient and to be more complete and accurate in your assessment; this, in turn, leads
to appropriate patient-specific care.
Closed-ended questions do play a role in communicating with a patient; however,the use of close-ended questions should be specific to the information you want to collect. For example, if you would like to know whether the patient took his or her bloodpressure medication in the morning to more accurately assess his or her blood pressure
reading, you might ask, “Did you take your blood pressure medications this morning?”
Additionally, you can use open-ended questions to determine the presence orabsence of certain symptoms or to further explore a symptom that the patient is experiencing. For example, after asking an open-ended question such as “What symptoms

Communication Skills

are you currently experiencing?” and hearing the response “My head hurts,” an appropriate closed-ended follow-up question would be “Is the pain behind your eyes?”

Leading Questions
Leading questions are those that suggest a particular answer. These questions lead apatient to provide a response that he or she perceives to be the answer that the interviewer wants to hear. An example of a leading question is “You do not miss any dosesof your medication, do you?” By phrasing the question in this manner, the patient feels
obliged to say, “No, I don’t” because the question implies that the patient should not
be missing doses, and, rather than contradicting your expectation, the patient merely
agrees. Therefore, to obtain an accurate response to your questions, leading questions
should be avoided.

Silence
The role of silence during your interaction with the patient is more significant than
you may realize. By allowing moments of silence after asking a question, the patientis able to reflect upon your question and provide a more thoughtful and accurate
response. However, silence may also indicate that the patient has not understood yourquestion. Nonverbal cues will help you determine the difference. You can use nonverbal cues to gauge each patient independently to determine the appropriate length oftime to be silent and/or when to break the silence. Determining the appropriate lengthof silence to use is definitely an art. In general, the silence should be long enough toprovide the patient a chance to gather his or her thoughts but not so long as to makethe patient feel uncomfortable.

“Why” Questions
As you are interviewing your patient, avoiding “why” questions may prevent thepatient from feeling as though he needs to defend his choices and actions. Although
it may be necessary to learn the reasoning behind the patient’s choices and actions,
the wording that you use may impact the response. For example, if you desire to learn
why a patient is missing doses of hydrochlorothiazide, instead of asking “Why do you
miss your doses?” you might ask “What causes you to miss your doses?” or “What aresome reasons for missing your doses of the hydrochlorothiazide?” The difference issubtle, but it may be enough to affect the way the patient perceives the question. Withthe “why” method, the patient may feel the need to defend him- or herself, whereas

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the “what” method allows the patient to reflect on his or her reasons without feelingas though you are offering judgment.

Nonverbal Communication
Nonverbal communication is the sending of messages to or from your patient without the use of words. This type of communication plays an important role in yourinteractions with your patients because it can be as powerful as the words that are
spoken. Nonverbal communication includes tone of voice, choice of language, facial
expressions, body posture and position, gestures, eye contact, appearance, and overallbehavior.1 A patient’s perception of nonverbal communication may be influenced byindividual and cultural differences. Therefore, you should be sensitive to cultural differences prior to making inferences about the patient based on nonverbal communication. Table 1.1 describes the various types of nonverbal communication and provides
examples for tone of voice, choice of language, and facial expression.

The Issue of Reliability
During the patient interview, you must assess the reliability of the information that isbeing conveyed to you. Many factors may affect a patient’s reliability, including certain psychiatric conditions, impaired cognitive function, inadequate memory recall, oreven a lack of understanding of the questions being asked. Therefore, it is important
to assess the patient’s reliability during the interview. Listening for and recognizing
clues that the patient may not be relaying accurate information, no matter the reason,takes experience. One way to address potential unreliability is to cross-reference theinformation from a variety of sources, including the patient’s profile, medical records,
and information from the pharmacy. In some cases, it may be necessary to include a
caregiver or family member in the interview session. This would need to be done ina manner that is consistent with the HIPAA procedures at your institution.

The Patient Interview The patient’s story is considered to be the key to the medical interview, and asking
the right questions and actively listening to the patient can best obtain this story. As
you interview the patient, you will come to realize that an organized approach provides a solid foundation, but you must follow the patient’s story in the order it isbeing told versus the patient answering your questions in a predetermined order. This
being said, it is necessary to know the core elements of the systematic approach toThe Patient Interview

Table 1.1 Types of Nonverbal Communication
Nonverbal­Communication

Tone of voice

Choice of­language

Description

ExampleOne may speak in a tone thatis persuasive, assertive, passive,condescending, kind, patient,impatient, confident, or unconfident.
Although the words that are spoken
are important, the tone in which
they are spoken may influence thepatient’s interpretation of what isbeing said. Similarly, you may beable to assess how a patient is feeling or reacting based on his or her
tone of voice. A patient may speak
in a tone that sounds encouraged,
dejected, sad, excited, angered, orconfused. By understanding thepatient’s tone, you may be able
to adjust your interaction with thepatient to improve communication.

“Smoking is harmful to your health.”

The language used may be simple
or complex, clear or confusing,or easy or difficult to follow. The
meaning of the words may be
influenced by the language used.

“Detrimental effects on health have beencaused by tobacco use. The studies haveshown that smoking leads to death, cancer, and hypertension. Choosing to ceasesmoking may lead to improvements inyour well-being.”

Practice saying this in various tones.
The patient’s interpretation will vary
based on your tone of voice. A condescending tone may cause the patient tofeel as though you are talking “down”
to him or her, such that the patient
may not want to discuss this any further with you, which, in turn, may makeyou miss an opportunity for smoking
cessation counseling. In contrast, saying this in a confident and assertive
tone may cause the patient to at least
hear what you are saying versus being
offended by the way you have said it.

The use of complex language that ismore difficult to follow may not only
cause the patient to be confused
about the message that is being
conveyed, but also to feel as though
he or she cannot connect with you, leading the patient to believe that you aredisinterested in his or her care.
The following statement is better:“Smoking causes harm to the body,
including high blood pressure, cancer,
and even death. Choosing to quit smoking will help your health be better.”(Continues)

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Table 1.1 Types of Nonverbal Communication (Continued )Nonverbal­Communication

Description

ExampleNow, not only are the words clearer,
but the patient’s ability to connect withyou, because of increased understanding, may improve as well.
Facial­expressions

Body postureand position

Many facial expressions are possible: smiling/frowning, looks ofastonishment, disappointment,
disapproval, surprise, shock, anger,
fear, happiness, and sadness. These
expressions may happen involuntarily and convey strong messages.
As a patient is speaking, it may beappropriate to smile, which could
mean you are encouraging thepatient to continue speaking, or it
could indicate that you are amused.
One may also look perplexed, indicating that either the patient or you
need more clarity.

A patient says, “Sometimes, I take mymom’s blood pressure medications
when I have a headache because that’s
how I know that my pressure’s up.”Sitting straight or slumped, relaxedor tense, and/or with hands
crossed over body may indicate
one’s desire to be a part of theconversation or it may reflect feeling nervous, anxious, or defensive.
Sitting straight may convey confidence. In addition, the distance orspace between you and the patient
may indicate the balance between
respect for personal space andbeing close enough to comfortably speak with the patient withoutbarriers. Typically, finding a place tosit where you are close enough toreach the patient but not touching
the patient is a good distance.

If the pharmacist is sitting slumped ina chair, the patient may perceive that
there is a lack of interest on the partof the practitioner to be present at thepatient visit. In the same vein, if thepatient is slouching, it may indicate alack of interest, and therefore rather
than just continuing to give information to the patient, it may be better topause, and ask the patient a reflective
question such as, “What do you think
about starting these new medications?”

Upon hearing this, you may feelsurprise, shock, and/or disapproval.
Although these feelings may be justified, allowing your facial expression toshow these feelings may discourage
the patient from divulging information
to you because of e
­ mbarrassment andchagrin. In contrast, looking perplexed
as you ask the patient why he or she
thinks a headache means that his or her
blood pressure is high may encourage
the patient to respond by explaining his
or her reasoning to you.

The Patient Interview

Table 1.1

(Continued)

Gestures/movements

The use of gestures such as hand
movements or nodding to show
encouragement/understanding
may be appropriate to complement
your words; however the overuse of
gestures, tapping of feet, or movingaround may be distracting. If yourpatient is moving around too muchor acting restless, it may indicate nervousness or discontent. In addition,
touching a patient on the shoulder
may show empathy or go together
with making a point; however, somepatients may feel uncomfortable withthis. You need to assess the patient’s
reaction to the touch to know thedifference.

If you are a practitioner that lightly
touches your patient’s shoulder or arm
to emphasize a point or show e­ mpathy,and your patient pulls back or looks at
you nervously, it may mean they
are not comfortable with touch andtherefore you should avoid touching
the patient in the future. Additionally,
if your patient appears to be movingaround too much, you can ask thepatient a question such as, “You seemto be ­pacing the room—what is on
your mind?”

Eye contact

If you keep glancing at yourcomputer screen or your phone, itappears to the patient that you are
not interested in what he or she
is saying; however, maintaining
continuous eye contact may makethe patient uncomfortable. Additionally, certain cultures consider
eye contact to be a sign of respect
whereas others think it is more
respectful to not make direct eye
contact. Therefore, you should takenonverbal cues from your patient
to maintain the right amount ofeye contact, understanding that alack of eye contact does not necessarily indicate dishonesty.

As computerized medical records are
becoming more prevalent, if you arereviewing and documenting information as the patient is ­speaking, it may
make the patient feel as though you
are not actively listening. During thevisit, you can start by telling yourpatient that you will be documenting
in the computerized medical record
throughout the visit to prepare thepatient. On the other hand, when
the patient is answering your questions, you should make eye contact
and document this information at alater time.

a patient interview to ensure that all of the components are addressed and eventually
documented and/or communicated in an organized manner that is recognized by all
healthcare ­professionals. It has been well documented in the medical field that effective communication with patients leads to better diagnosis and treatment, as well as an
improved provider–patient relationship.5 Although most of this research is related to11

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physician–patient communications, it can easily translate to communications between
the pharmacist and the patient. This is because pharmaceutical care, like the care provided by a physician, involves (1) curing a patient’s disease, (2) eliminating or reducing
a patient’s symptoms, (3) arresting or slowing a disease process, and (4) preventing a
disease or symptoms.6 Even though a pharmacist does not make disease diagnoses like
physicians do, a pharmacist must nonetheless evaluate the information obtained fromthe patient interview, including the possibility of certain diagnoses, to appropriately
create an assessment and plan, which may include a referral to the patient’s physician
or an emergency room for further evaluation.

Components of the Health History
Chief Complaint
The chief complaint (CC) is the issue or issues that the patient is presenting withand the primary reason for the visit. This is typically documented in the patient’s own
words and is therefore quoted in the written or oral presentation. One way to determine the patient’s chief complaint is by asking, “What brings you here today?” Somepatients may have an actual complaint, while at other times they may be visiting for ageneral reason, such as to pick up a new or refill prescription or for a follow-up visit.
In the case of no overt complaint, the chief complaint may be goal-oriented, such as“I am here to pick up my refills,” “I am here to discuss my labs,” or “My doctor told
me to see you about my sugars.”4 At times, the patient’s chief complaint may seem relatively minor compared to the assessment; however, regardless of the final diagnosis, thechief complaint should be the patient’s primary complaint. For example, a patient may
come in complaining of “being out of his furosemide” and, upon evaluation, it may be
determined that the patient is experiencing acute heart failure. This assessment and thesubsequent plan will be discussed elsewhere in your documentation.

History of Present Illness
The history of present illness (HPI) is the story of the illness.7 The pharmacist willfurther explore the chief complaint as well as any other potential problems by asking
questions about any recent or remote history that may be related to the current illness.
The goal of the HPI is to ascertain a complete, accurate, and chronological accountof the illness from the patient. Seven attributes need to be addressed to obtain a wellcharacterized description of the complaint or symptom: location, quality, quantity or
severity, timing, setting, factors that aggravate or relieve the symptoms, and associatedmanifestations.2 Table 1.2 describes each attribute in more detail and provides anThe Patient Interview

Table 1.2 Seven Attributes of a Symptom
Example for Chief Complaintof Swelling

Attribute

Exploration

Location

Specifics about where the symptom is
occurring. In some cases, it is important
to ask the patient if it is okay for you toinspect the area.

“Where is the swelling
located?”Quality

Describe the symptom in terms of characterization. For example, if the patient
is in pain, characterize the pain by using
descriptive adjectives, such as stinging,shooting, or crushing.

“Describe the swelling. How
much worse is it now than it
normally is?”Quantity/severity

Quantify the severity of the symptom. If
the symptom is pain, ask the patient torate the pain on a scale of 1 to 10.

“Would you say that thisswelling is causing your leg to
be twice its normal size?”

TimingFind out when the symptom started andif there was anything occurring at the time
to link it to the onset of the symptom. Also
clarify how long the symptom has been
occurring and the frequency of occurrence;that is, is it constant or intermittent?

“When did the swelling start?
How long does it last? Is it
worse at certain times during
the day?”

Setting

This includes addressing the possible
cause of the symptom.

“Have you noticed whatcauses the swelling?”

Factors that
aggravate or
relieve thesymptom

Determine what makes the symptom better or worse. Ask about any medications
or nonpharmacologic therapies used torelieve the symptoms and their efficacy.
Ask questions to find out what makes thesymptom worse. For example, the symptom may be worsened by certain environmental conditions, exertion, or stress.

“What makes the swellingworse or better? Do you
notice a difference in themorning versus when you
have been on your feet during the day? What did you try
for the swelling? How did it
work?”

Associatedmanifestations

Note any other symptoms the patient isexperiencing. Also ask about symptoms
that may be a consequence of the primary
symptom.

“What other symptoms do
you have? Are you experiencing any shortness of breath or
trouble walking?”

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example. As you talk with the patient, the flow of the HPI may depend on what thepatient wants to tell you; however, most of the time all seven attributes of a symptom
must be addressed to completely characterize the patient’s complaint and to develop
the HPI. For example, if a patient complains of a cough, it is not necessary to ask
about the “location” of the cough. However, if a patient complains of a headache,specifying the exact “location” of the pain (i.e., front, back, or side of the head) willassist in the assessment.
Asking questions during the HPI is akin to putting together a puzzle. A patient
who is telling you parts of his or her story may not realize which parts are pertinent.
For example, the patient may not know how and what information needs to be relayed
to you so that you can make a complete assessment. It is like a puzzle in that you may
know what the completed puzzle will look like; however, you have to pick up eachpiece; examine its shape and color for hints, such as having a flat side, which indicatesthat it is a border piece; and then place it near other “like” pieces until you are able
to fit all the pieces together. You, as the pharmacist, should start thinking of various
questions to ask the patient so that the patient’s responses, or the puzzle pieces, may
be put together to ascertain or rule out certain assessments. It is important to ask
open-ended questions and appropriately follow up in order to obtain the right pieces
of information to put together the HPI. In the case of the patient interview, you will
be assessing each piece of information for its reliability, completeness, and relevanceto the problem.7 As the details of the problem are further explored, you need to process and evaluate this information to find the link among symptoms so appropriate
assessment may occur.7
One way to ascertain this information is by focusing on pertinent positives andnegatives, which may be thought of as the hints that will lead to you putting the puzzle
together. In addition to asking the patient open-ended and focused questions to learn
the characterizations of his or her chief complaint or symptom, the HPI may include
additional questions that focus on the presence or absence of certain symptoms that
could be related to your differential diagnosis or the patient’s medical condition. You
may need to assess a patient’s medical condition during the patient interview even if
the patient does not have any complaints regarding that medical condition. For example, in a patient who has heart failure (HF), you may need to ask about the presenceor absence of certain symptoms to determine whether the patient’s HF is controlled
or if the patient is experiencing an exacerbation. Therefore, you may ask the patient
about symptoms that are pertinent to the assessment of HF, such as the presence orabsence of edema, the use of extra pillows at night to avoid lying flat, and shortness ofbreath. If the patient has any of the aforementioned symptoms, they would be termed­pertinent positives, or the presence of symptoms that are related to the medical

The Patient Interview

condition that is being assessed. In contrast, if these symptoms are absent, they would
be termed pertinent negatives, or the absence of symptoms related to the medical
condition being assessed. Asking these focused questions about pertinent positive andnegative symptoms contributes to the assessment of heart failure in this patient.
Another way to use the technique of asking about pertinent positives and negatives is to rule out or rule in possible diagnoses. For example, to determine a possible
cause for the polyuria (increased urination) a patient is experiencing, you will needto ask focused questions. First, you consider the most common causes of polyuria,
which include, but are not limited to, diabetes or a urinary tract infection (UTI). To
further explore the reason behind the polyuria, you will ask about symptoms that arepresent in either diabetes or a UTI, including polydipsia (increased thirst) and polyphagia (increased hunger) or dysuria (painful urination) and hematuria (blood in theurine), respectively. Additionally, pertinent positives or negatives are not limited tosymptoms but may include other information obtained from the family history or
past medical history. For example, in a patient with polyuria, it will be pertinent tofind out if the family history is significant for diabetes or if the patient’s past medical
history (PMH) includes recurrent UTIs. In order to accurately make a diagnosis, incollaboration with a medical professional, these findings from the patient interview
would need to be coupled with diagnostic tests, including blood work and/or urine
analysis. The purpose of this example is to illustrate the use of questions to discover
either the presence or absence of pertinent findings that assist in painting an accurate
and complete picture of the patient’s story.

Past History
The past history includes the past medical history, surgical history, history of childhood illnesses, and obstetric/gynecologic history. Aspects of health maintenance, suchas immunizations and screening tests, should be included as well.4 When interviewing
the patient, all of these aspects fall under the umbrella of past history; however, upon
documentation, these sections may be separated by type of past history, such as PMH,
surgical history, or health maintenance/immunizations. Each of the components of thepast history should include the information discussed below. As pharmacists, we do not
usually obtain a complete past history from a patient; rather, we rely on the information documented by a medical student, resident, or physician. However, sometimes
it is appropriate to ask the patient about parts of his or her past history and/or to use
any information gathered previously to determine the appropriate care for the patient.
Therefore, it is vital to know the components of the past history and the questions thatneed to be asked.

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Chapter 1 / The Patient Interview

Past Medical History The PMH includes chronic as well as past acute medical
conditions, including diabetes, hypertension, hyperlipidemia, hepatitis, and asthma,
as well as any history of pneumonia, cancer, or Lyme disease. One way to ask patients
about their PMH is, “What medical conditions do you have or have you been told
you have?” You may notice that a particular patient may have several conditions documented, but upon further questioning determine that the patient is not including allof them. To ensure completeness, you may need to ask the question in various ways
and, at times, gently probe. For example, if you notice that the patient is not surewhat you mean by “medical conditions,” you might ask, “Do you have any medical
conditions, such as diabetes or high blood pressure?” Or, if you note that the patient
has albuterol in his or her medication profile but has not mentioned any pulmonaryrelated conditions, you might ask, “What are you taking the albuterol for?”
Surgical History The surgical history should include the type of operation, when
it occurred, and the indication for the operation. You might ask the patient, “Whatsurgeries have you had?” and “When did you have this surgery?” Examples of thesurgical history that would be pertinent to pharmacists would be an assessment of
uncontrolled pain from a recent knee replacement surgery or the determinationof which vaccines should be avoided in the patient who has had a splenectomy.
Childhood Illnesses Pertinent childhood illnesses include measles, mumps,
whooping cough, chickenpox, rheumatic fever, scarlet fever, and polio. You could ask
the patient, “What childhood illnesses, such as measles or chickenpox, did you haveas a child?”
Obstetric/Gynecologic History The obstetric history includes the number ofpregnancies, including deliveries, miscarriages, and terminations, as well as the year,
months gestation, complications, and infant weight for each pregnancy. The gynecologic history includes onset of menstruation, date of last period, use and type of birthcontrol, and sexual function. Although the pharmacist does not typically gather thishistory, some of this information may be pertinent to patient care provided by thepharmacist. For example, knowledge of an infant’s birth weight can help you determine whether the mother has a risk factor for diabetes, which, in turn, may influence
whether you would recommend diabetes screening for the patient. One way to gather
this information would be to ask directly, for example, “There are many risk factors
for diabetes, including the birth weight of your children. How much did your children weigh when they were born?” or “Did any of your children weigh 9 or morepounds when they were born?”

The Patient Interview

Another example of asking questions related to the gynecologic history is in thecommunity setting when a patient requests Plan B One-Step, and you must determine whether Plan B One-Step is appropriate and what other counseling may be necessary. In this situation, you might ask the patient questions such as, “When did theunprotected sex happen?” “To ensure that you are not pregnant now, when was thedate of your last period?” or “Unprotected sex carries the risk of sexually transmitted
diseases, and Plan B One-Step will not prevent this. Are you worried about this?”
Such questions enable you to assess the appropriateness of Plan B One-Step and thepossible need for the patient to seek medical attention.

Health Maintenance/Immunizations
This part of the medical history includes information on what immunizations thepatient has received, such as influenza, pneumococcal, tetanus, and hepatitis B, as wellas the dates they were obtained. Based on this information, you can then recommend
any new or booster immunizations the patient may need. The dates and results ofscreening tests, such as mammograms, Pap smears, and tuberculin tests, should also
be included. Information on diabetes and cholesterol screenings may also be includedin this section, even though these tests are part of the objective data. These screening tests typically occur because of recommendations from guidelines and are meant
to allow for preventative treatments and early diagnosis; therefore, asking the patient
about this during the past history component of the patient interview enables you tomake recommendations based on the information you have gathered.

Family History
The family history (FH) is health information about the patient’s immediate relatives. These relatives include parents, grandparents, siblings, children, and grandchildren. Because many medical conditions have a genetic component, the purpose of thefamily history is to determine potential risks factors for the patient’s current and future
health. Typically, relatives such as cousins, aunts, and uncles are not included in thefamily history; however, for certain medical conditions that carry a high genetic linkquestions about the patient’s family history may be appropriate.7
When inquiring about family history, you should ask whether the person whose
history is being provided is alive or deceased; determine the presence or absence of
medical conditions such as hypertension, coronary artery disease, hyperlipidemia, diabetes, pulmonary diseases, cancers, or thyroid disorders; and gather information onthat person’s psychiatric history, addictions, or allergies. In addition, if the person is17

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Chapter 1 / The Patient Interview

deceased, ascertain the age at death and the cause of death.4 It is important to include
this specific information because it may determine certain risk factors a patient may
carry. For example, if a patient’s father died at the age of 45 secondary to a myocardial
infarction, the patient then has a risk factor for coronary artery disease. This risk factor,
in conjunction with other pertinent history, will determine the patient’s goal low density
lipoprotein (LDL) and drug therapy necessary to achieve this goal. One way to determine the patient’s family history is to ask, “Are your parents and grandparents alive?
What was the cause of death? At what age did they pass away?” A general question, suchas “What health conditions do or did your parents/grandparents/children have?” maybe sufficient, but sometimes it may be necessary to ask a more focused question, such as“Do or did your parents or grandparents have heart disease or diabetes?”

Personal and Social History
The personal and social history (SH) is the part of the interview where we learn
about the patient’s life, including health behaviors and personal choices. The basicsocial history consists of asking the patient about past and present use of tobacco,
alcohol, and illicit substances. If these are currently consumed, you should inquire as
to how much and how often each is utilized. In addition, if a patient is a former userof any of these substances, it is vital to ask the patient at subsequent visits if he or she
remains abstinent or if relapse has occurred. Because many of the these questions canbe very personal and some patients may be reluctant to share such information, either
out of embarrassment or fear of being judged, you should ask these questions withsensitivity and respect. However, it is important to be direct so that patients realize
these questions are important with regard to their care.

Tobacco Use You should ask patients if they currently smoke or if they havesmoked in the past. For both former and current tobacco users, you should ask atwhat age they started (and quit); what form of tobacco they use or used, including
cigarettes, chewing tobacco, and/or cigars; and quantify the amount. For cigarettes
smokers, you should ask how many cigarettes or packs they smoke (or smoked) per
day. One way to ask this question is, “How often do you use tobacco products?” By
asking this question in an open-ended manner, patients who consider themselvessocial smokers may be more likely to disclose information about their tobacco use.
Had you asked, “Do you smoke?” these same patients may be more likely to say no
because they do not smoke often.
Alcohol Use Similar to tobacco use, you want to ask a patient, “How often do you
drink alcohol?” You also want patients to quantify the amount they drink and how often

The Patient Interview

they drink. It is necessary to ask specific questions, because although one drink is technically considered to be 12 ounces of beer, 5 ounces of wine, or 1.5 ounces of liquor,a patient’s definition of “one drink” may vary. You could ask the patient, “What do
you typically drink?” “How much wine/beer/liquor do you have every day?” or “Howmany days a week do you drink?” To gather more information about what one drink
means to the patient, specifically ask, “How much liquor do you put in one drink?”

Illicit Substances Use Patients may hesitate to answer questions about illicit drug
use honestly because they are afraid of negative consequences. It will help if you arestraightforward and nonjudgmental when asking about illicit substance use. One way
to ask this question is, “Do you currently take, or have you taken in the past, any illicit
drugs? If so, which ones?” Remind the patient that he or she should feel comfortabledisclosing this information to you because you are seeking this information for the
purpose of providing patient care and that you will not report the use of any illicit
drugs to law enforcement authorities.
In addition to past and present tobacco, alcohol, and illicit substances use, a more
complete personal history also includes educational level, composition of the familyof origin and the current household, personal interests, and additional lifestyle information, such as dietary habits, caffeine intake, exercise habits, and an assessment of
the activities of daily living (ADL) to determine baseline function, especially in disabled or older patients.4

Review of Systems4
The review of systems (ROS) is a systematic, head-to-toe evaluation of the presenceor absence of symptoms. It includes the presence of any symptom, even one that thepatient may not have deemed to be significant or may have forgotten because of his or
her focus on the chief complaint. Generally, the medical student, resident, or physician
completes the comprehensive ROS questioning; however, pharmacists may need to
ask a patient about the presence or absence of pertinent symptoms related to the present illness. Because of this, it is necessary to understand what is included in the ROS.
Additionally, pharmacists may also be part of a medical team, and therefore should beaware of all of the components of a patient interview even if they are not the ones asking the questions. Prior to starting this part of the interview, let the patient know thatyou will be asking several questions to assess any potential symptoms he or she may be
experiencing. Oftentimes, some of these systems may be addressed concurrently withanother part of the interview. For example, after checking the patient’s blood pressure,
you may ask if the patient has had any dizziness or palpitations.

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Chapter 1 / The Patient Interview

Physical Examination
The comprehensive physical examination (PE) is most often completed by a medical student, resident, or physician. They are taught to develop their own systematic approach toensure a thorough and accurate physical exam. The comprehensive physical exam includes
measurement of vital signs such as height, weight, temperature, blood pressure, and pulse,
as well as the observation, inspection, and palpation of the patient’s body from head to toe.
Although physicians often complete this part of the patient assessment, pharmacists arealso skilled at completing parts of the physical exam. These parts include, but are not limited to, measuring vital signs and inspecting and palpating parts of the body related to thepatient’s complaint. For example, a pharmacist may assess the severity of lower leg edemaby inspecting and palpating the area of swelling. Additionally, pharmacists may conductmental status examinations or assess the effects of a stroke by examining the patient for
facial droop, arm drift or strength, and speech abnormalities.8

Medication History
The medication history is a vital component to the patient interview and is the area
where the pharmacist will dedicate the most time. Medications include prescription
and over-the-counter (OTC) drugs as well as herbal products. The medication history
provides insight into the patient’s current and past medications, adverse drug reactions
or allergies, adherence, the patient’s own understanding about his or her medications,and any other concerns a patient may have regarding his or her medications.9 Asking
pertinent questions with a systematic approach, utilizing appropriate technique, andactively listening to the patient will enable you to collect a thorough and accurate
medication history. This, in turn, will enable you to identify, prevent, and/or resolve
any active or potential drug-related problems. Additional reasons to obtain an accurate
medication history include the following:10• Ruling in or out a drug-related adverse effect• Preventing drug–drug, drug–food, or drug–disease interactions• Monitoring for clinical signs that may be masked due to a drug
• Evaluating laboratory findings appropriately, as certain drugs may affect theresults• Preventing prescribing errors
Additionally, the inclusion of a thorough OTC medication and herbal producthistory is vital for the following reasons:• It verifies that the patient is choosing the appropriate OTC medication or
herbal agent and that it is being taken correctly.

Medication History• It gives you the opportunity to assess for any drug–drug or drug–disease interactions that may be occurring with an OTC or herbal product.
• It will give you the opportunity to counsel and educate the patient about OTC
medications and herbal products, because some carry more risks than benefits.
For example, a patient who is taking warfarin may also tell you she is taking ibuprofen 200 mg twice daily for arthritis pain. This information provides you with anopportunity to assess the patient’s arthritis pain and inquire about what other agents
have been tried to treat the pain. After evaluating the patient, you may determinethat acetaminophen is the more appropriate drug for this patient. You would thencounsel regarding the increased risk of bleeding associated with concomitant warfarin
and ibuprofen use, as well as recommend acetaminophen, being sure to include all thecomponents of self-care counseling described later in this chapter.

Components of a Medication History
To effectively and efficiently conduct a medication history, appropriate training, education, and practice are necessary. You should know all the questions that need to be
asked, the various ways in which the questions may be asked, the appropriate use ofinterview techniques, and the many sources of information that should be utilized.9
It is necessary to know the contents and significance of the various components
of a medication history. This section provides examples of how to ask the questions
related to the medication history along with the explanation of each component;­however, it is important to realize that these examples demonstrate just one way to
ask questions, and you might find that your own communication style lends itself
to a ­different way of asking the questions. You must find a way of having a natural­discussion with the patient that works for you, and this will take a lot of practice.

Introduction
Prior to starting the medication history, you should introduce yourself by telling thepatient and/or caregiver your name and title. Be sure to confirm the patient’s identitywith at least one patient identifier, such as the patient’s birthday, telephone number,or home address. Additionally, you should describe the purpose of the medication
history, tell the patient the amount of time you expect that it will take to conduct the
medication history, and obtain permission to collect the information.
The following is a sample dialogue for the introduction: “Hello, my name is Shaan
Smith, and I am a pharmacy student. Before we get started, I would like to make sureI am speaking with the right person. May I get your full name and address, please?”21

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Chapter 1 / The Patient Interview

Once the patient’s identity has been confirmed, you could continue by saying,“I will be taking a medication history from you today. This means that I will be asking you questions about all the medications you are currently taking and get some
information about medications you may have taken in the past and any side effects orallergies you may have. All of this should take about 10 to 15 minutes. Would that be
alright with you?”

Medication History
After the introduction, you will need to obtain information on all of the prescription
and OTC medications as well as any herbal products the patient is currently taking.
Additionally, you may need to specifically ask the patient about inhalers, injections,
OTC products, and herbal medications, because patients oftentimes forget to mention these things because they tend to only think of “pills” when asked about their
medications.
For each medication, you will need to determine the product’s name, strength,dose, indication, frequency, timing of administration, duration of use, and the prescribing physician. The information can be gathered in a number of different ways,
and the method you use may depend on the clinical setting. The best way to obtain
this information in a planned encounter is via the “brown bag” method. Prior toyour planned meeting, ask the patient to bring in all of his or her medication bottles,­including prescription and OTC medications and herbal supplements. During themeeting, ask about the dose, indication, frequency, timing of administration, and duration of the use. By looking at the bottles, you will already know the name and strengthof the medication as well as the prescribing physician. Even though the directions are
written on the label, you should ask the patient how he or she is taking a particular
medication, because there may be discrepancies between the written directions andhow the patient actually takes the medication.
Another method is to look at a written list of medications that is either kept by
the patient or found in the medical chart. Sometimes a patient may say, “I am taking everything that you have on your list” when you start asking them questions
about their medications. One way to address this is by explaining the purpose of the
medication history. For example, you could tell the patient, “Although I do havethe ­medications listed in my chart, it would be good to go through each medication
one by one to ensure that my list is accurate and truly shows what you are taking now.”
Another option is to simply ask the patient about all the medications he or she
is taking. Unfortunately, patients do not always remember the names, doses, or how
they are taking their medication; accordingly, this method may not produce the mostMedication History

complete medication history. With the patient’s permission, you can call the patient’s
pharmacy or primary care physician to obtain the most current medication list, or you
can even call the patient’s home to speak with someone who can read the informationfrom the medication bottles.
If a patient is presenting to the emergency room or is in a hospital where it is
not possible to look at the patient’s medical chart, you should ask the patient, family
member, or caregiver if he or she has a written list. If such a list is not available, obtain
permission to call the pharmacy, primary care physician, and/or the patient’s home, as
discussed previously.
Regardless of the method utilized to complete a medication history, the information that needs to be collected is the same. The various components of the medication
history are listed below. These components are the same for each medication, including prescription and OTC medications and herbal products.

Medication Name The name of the medication can be located on the label or the
medication list. One way to obtain this information is to ask, “What are the namesof the medications that you are currently taking?” When obtaining this information,
make sure to determine if the medication is extended release (ER), long acting (LA),sustained release (SR), or immediate release (IR), and whether the patient is taking
the brand name or generic version. For example, if a patient states that he or she istaking metoprolol, you must determine if it is tartrate or succinate. With regard togeneric versus brand name, for some medications with narrow therapeutic indexes,
such as levothyroxine or warfarin, changing between manufacturers may cause fluctuations in drug levels in the blood; therefore, including manufacturer information isbeneficial. If a patient does not know this information, another way to ask this question is, “Does your levothyroxine tablet look the same as it always has?”Strength and Dose Information for strength and dose is also found on the label
or on a medication list. You can also ask the patient, “What is the dose of the medication you are taking?” Make sure to include information for both the strength and its
corresponding units. For example, levothyroxine 50 mcg or metoprolol ER 50 mg.
Frequency Although this information is often included in the directions written
on the label, you should ask the patient, “How often do you take this medication?” Insome cases, the patient may be taking the medication differently than written on thelabel. This could occur for several reasons. For example, a patient may have been told
by his or her physician to double or lessen the dose, or the patient may have misread
the directions or be confused about the correct way to take it.

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Chapter 1 / The Patient Interview

Frequency of a PRN Medication Obtaining the actual frequency of a PRN(i.e., as needed) medication enables you to assess whether the patient is taking the
medication appropriately and whether the disease state is being managed effectively.
One way to determine this frequency is to ask the patient, “In a typical day (or week),
how many times do you take this medication?” or “How many tablets do you take ata time and how often do you take them?” For example, if a patient states that he or
she is taking albuterol most days of the week for shortness of breath, it is important to
ask the patient what causes the shortness of breath, how many inhalations are taken at
one time, how many times a day the medication is taken, and what the time interval
is between doses. This enables you to ensure that the patient is at or below the maximum dosage and potentially assess the severity of the patient’s asthma, which, in thisexample, may warrant additional medications.
Timing To determine the timing of medication administration, you can ask thepatient, “When do you take this medication?” If it is a medication requiring dosing at
multiple times during the day, be certain to ascertain the amount of time between doses.
For example, if a patient says that he or she takes a twice-daily medication with breakfast
and dinner, you should ask, “What time is breakfast and dinner?” because the medication may require 12 hours between doses but the amount of time between the patient’s
breakfast and dinner may be only 8 hours. Another reason that timing is key is becausesome medications need to be taken at certain times of day or in relation to a meal. For
example, some statins are most effective when taken in the evening, whereas other medications need to be given on an empty stomach or separated from other drugs.
Determination of timing is especially important for a patient who is being admitted to the hospital. It is necessary to obtain the timing of each medication so that thissame schedule can be followed in the hospital. Also, the time of the last dose of each
medication is vital to ensure that a patient does not receive an additional dose of a
medication on the day of admission that he or she may have already taken that morning at home. One way to avoid this is to have the prescriber specify when the first doseof each medication is due when writing the initial medication orders on admission.
Indication Inquiring about the indication for each medication enables you toassess the patient’s understanding of his or her medications and to provide patientspecific education. You can determine the indication by asking the patient, “What are
you taking this medication for?”Adverse Reactions Adverse reactions are also known as side effects or ­intolerances.
Ask the patient, “What side effects are you experiencing with any of your medications?”

Medication History

You can also use a closed-ended question, such as “Do you think any of your medications are causing you to feel anything out of the ordinary?” Sometimes a patient may
complain of a symptom that is actually an adverse reaction. Other times, a patient
may link the start of an adverse effect with the start of a medication. Asking thisquestion in a general way allows the patient to reflect on or mention any way he or
she may have been feeling differently without realizing that a medication could becausing the reaction. Additionally, it is important to get detailed information about
the adverse reaction so that you can assess the severity of the adverse reaction anddetermine the next course of action, which may include discontinuing the medication, adding a medication to counteract the adverse effects, and/or obtaining laboratory tests or recommending further testing to determine the cause or severity of theadverse reaction.

Past Medication Use At times, it can be helpful to find out what medications
the patient has taken in the past. For example, certain patients with diabetes need to
be on an angiotensin-converting enzyme inhibitor (ACE-I) such as lisinopril. After
conducting the medication history, you may discover that the patient is not taking an
ACE-I even though the guidelines recommend this. Prior to discussing this with thepatient’s physician, you should inquire whether the patient has taken an ACE-I in
the past. For example, you might ask a probing question, such as “Have you taken
any medications for blood pressure or for your kidneys in the past?” or “Have you
taken a blood pressure medication in the past that may sound like there is a ‘pril’ atthe end of the name, such as lisinopril or enalapril?” Another way to examine past
medications is by cross-referencing the information that the patient has given you
with his or her pharmacy and/or medical chart. You may discover that the patient
may not be on an ACE-I due to an adverse reaction in the past or because of costissues. However, you might also discover that the patient has never been on an ACE-­
inhibitor, in which case you would evaluate for any contraindications and potentiallydiscuss adding such a medication with the patient’s physician.
Medication Adherence A key component to the medication history is an assessment of medication adherence. As the saying goes, a medication only works well if it
is being taken. Assuming that a patient is taking the medication is not always a safe
assumption. Therefore, it is important to ask the patient how many doses of each
medication are missed, what the reasons are for missing doses, and what the patientdoes if a dose is missed. You could ask the patient, “How often do you miss doses ofany of your medications?” or “In the last week, how many doses did you miss of your
medications? Which medications? What caused you to miss those doses? What did

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Chapter 1 / The Patient Interview

you do when you realized that you forgot to take the medication?” By asking thesequestions, you are learning how adherent a patient is to the medication regimen andwhat may be causing the patient to miss doses.
The information you gain about adherence will enable you to better target your
medication counseling. For example, you may learn that a patient is taking a daily
medication every other day because of the high cost or because of feelings of dizziness
whenever he or she takes it. Once you understand the patient’s reasoning, you canmake appropriate adjustments to the regimen, if necessary. For example, if the patientis unable to afford the drug, you may be able to recommend a less expensive therapeutic alternative; if the reason for missed doses is due to an adverse reaction, further
evaluation is warranted to determine whether the adverse reaction is truly because of
the medication or possibly due to another reason. Additionally, you may learn that apatient merely forgets to take the evening dose of a twice-daily medication. In thiscase, you can see if a once-daily option is available or provide suggestions to improve
the patient’s ability to remember the dose, such as using a cell phone alarm or leaving
the medication next to the bed.
In any case, prior to making any recommendations, it is important to thoroughly
explore a patient’s level of adherence and reasons for lack of adherence. In addition,
when asking about adherence, you want to make sure the patient does not feel like heor she is being scolded or reprimanded. Be sure to ask without judgment and avoid
leading questions such as “You don’t miss any doses, right?”

Allergies Inquiring about any allergies the patient may have experienced at any
point in his or her life is just as important as learning about all the medications thepatient is taking. Ask the patient about any allergies to medications or foods and todescribe what type of reaction occurred. You must determine the allergy trigger; thetype of reaction, including its severity; and how the allergic reaction was resolved.
This information will help you determine whether the reaction is truly an allergy orrather an adverse effect. You could ask the patient, “What allergies do you have?”
A closed-ended question would be, “Do you have any allergies to any medications
you have taken or any foods?” Once you determine which allergies the patient has,
you should ask, “What happened when you took that medication? What did you
need to do to make the reaction go away?” By documenting all of this information,
you can determine which medications to avoid in the future based on cross-reactivity
that may occur between different classes of drugs or because of the severity of thereaction. For example, if a patient says that she is allergic to amoxicillin and refuses totake it ever again in the future because of the stomachache she experienced, then in
the future you may be likely to recommend a cephalosporin; however, if the reaction

Medication History

to the amoxicillin was anaphylaxis, you would most likely avoid cephalosporins dueto the risk of cross-reactivity.

Closing the Interview
As with all patient interactions, closing the medication interview includes assessing thepatient’s understanding, providing an opportunity for the patient to ask you questions,and discussing any follow-up plans. Because the purpose of the medication history
is primarily for you to gather information, assessing the patient’s understanding will
only occur if issues were identified during the medication history and counseling wasprovided. If this occurred, you may choose to utilize the teach-back method, whichmeans you ask the patient to repeat the education that you have provided so that you
can assess the patient’s understanding and correct any misunderstandings the patient
may have had.
Always ask if the patient has any questions. Even if questions were asked throughout the interview, it is still necessary to give the patient a chance to ask any otherquestions that may have arisen or that may have been left unanswered.
After addressing any questions, let the patient know whether follow-up is necessary. This will depend on what occurred during the medication history and the setting
where the session took place. For example, if changes were made to the patient’s medication regimen, you may need to schedule a follow-up appointment. If you were conducting a medication history at a health fair, you may tell the patient to follow up withhis or her physician in a specified amount of time or phone the physician if you havea medication concern that cannot wait. Additionally, if a medication history occurredin the hospital, you should document your findings in the medical record so that the
medical team has your complete medication history and can address any issues anddiscuss follow-up needs during the discharge process. If you will be involved in thepatient’s care at the hospital or in a setting that the patient may need to get in touchwith you, be sure to include your contact information.
The following is an example of how you might close an interview: “Thank you forall the information you have given me. I will be sure to document this in your medical record. Before you go, I just wanted to make sure that we discussed how to takeyour albuterol inhaler properly. Would you mind showing me how you will use yourinhaler when you get home?” The patient should then show you his or her technique.
You should then make any necessary corrections and have the patient demonstrateusage once again to ensure that the technique is being performed correctly. You could
then ask, “What questions do you have for me?” After addressing all of the patient’s
questions, you might say, “Well, it was great meeting you. Please call the pharmacy

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Chapter 1 / The Patient Interview

if you have any questions. Our number is on your label.” If you are at the hospitaland you are only having a one-time interaction with your patient, you can say, “Well,
thank you again for completing the medication history. I will be sure to share thisinformation with the medical team. If any questions come up, please be sure to ask
someone on the medical team.”

The Patient Interview in the Community Setting
Many patients present to a community pharmacy with self-care complaints seeking
recommendations for an OTC medication. Prior to making a recommendation, thepharmacist must first speak with the patient about his or her chief complaint so that an
appropriate plan can be determined.
The patient encounter in the community setting generally occurs in one of two
ways: either the patient presents to the pharmacy counter seeking advice or the pharmacist or pharmacy student notices the patient perusing the aisles and approaches
him or her. In either case, the patient interview that should take place is the same inorder to appropriately assess the situation and create a complete plan. First, the pharmacist or pharmacy student should introduce himself or herself, ask for permission
to assess the problem and provide advice, and/or tell the patient that he or she will
be asking questions prior to making any recommendations. Second, many questions
must be asked in order to properly assess the patient. In contrast to an ambulatory
care setting, both the pharmacist and patient are usually restricted in the amount oftime they can spend exploring the complaint and discussing the recommendation in acommunity pharmacy setting. However, even with the time constraints, appropriatequestioning must occur in order to advise the patient appropriately. Several methods
have been developed and mnemonics created to assist the pharmacist in asking questions about the patient’s chief complaint in a methodological manner.
Mnemonics include WWHAM, AS METTHOD, CHAPS-FRAPS, Basic 7,
PQRST, and QuEST/SCHOLAR-MAC (Table 1.3).11,12 Although each of theseapproaches is valuable in providing a methodological means of patient assessment,
unfortunately none of them include all the questions that need to be addressed. For
example, many of the methods do not include a determination of who the patient
actually is, which is important because in some cases the individual asking you a question about a medication is not the person who will actually be taking it. In addition,
the only method that describes what to do following the assessment is the QuEST/SCHOLAR-MAC method.11
For example, say you have a patient who presents to the counter with a bottle ofacetaminophen and asks, “How many should I take for my pain?” Prior to answering

The Patient Interview in the Community Setting

TABLE 1.3 Mnemonics to Assess a Patient’s Self-Care Complaints
Mnemonic

Information Gathered

WWHAM

Who is the patient?
What are the symptoms?
How long have the symptoms been present?
Action already been taken by the patient?
Medication already been taken by the patient?

AS METTHOD

Age
Self or someone else?
Medications
Exact symptom
Time or duration of symptoms
Taken anything?
History of diseases
Other symptoms
Doing anything to worsen or alleviate condition?

CHAPS-FRAPS

Chief complaint
History of present illness
Allergies
Past medical history
Social history
Familial history
Review of other symptoms
Assessments
Plan
SOAP (Subjective, Objective, Assessment, Plan)

Basic 7

Where
What

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TABLE 1.3 Mnemonics to Assess a Patient’s Self-Care Complaints (Continued )Mnemonic

Information Gathered

Quality
Severity
TimingContext
Modifying factors
Associated symptoms
PQRST

Palliation and provocation
Quality and quantity
Region and radiation
Signs and symptoms
Temporal relations

QuEST

Quickly and accurately assess the patient
Establish that the patient is an appropriate self-care candidate
Suggest appropriate self-care strategies
Talk with the patient

SCHOLAR-MAC

Symptoms
Characteristics
History
Onset
Location
Aggravating factors
Remitting factors
Medications
Allergies
Conditions

Sources: Buring SM, Kirby J, Conrad WF. A structured approach for teaching students to counsel self-care patients.
Am J Pharm Educ. 2001;71(1):8; Berardi RR, McDermott JH, Newton GD, et al. Handbook of ­nonprescription
drugs: An interactive approach to self-care. 14th ed. Washington, DC: American ­Pharmacists Association; 2004.

The Patient Interview in the Community Settingwith the dosing information, it is your duty to ascertain that the patient is selecting thecorrect medication. You can do this be saying, “Hello, my name is Ari Jones, and I am
the pharmacy student working here. Before I answer your question, would you mind
if I ask you a few questions to ensure that the medication you have selected is the mostappropriate medication for you?” Once permission has been granted to continue with
the interview, you need to ask who the medication is for, because the person who are
speaking with may have come to the pharmacy to seek advice for someone else, such asa child, parent, or friend. Therefore, you should ask, “Who is this for?”The next few questions will be related to finding out what the symptom is andcharacterizing it. Most likely you will start by asking, “What symptoms do you have?”
Once the patient tells you which symptoms are present, it will be your responsibility
to determine whether you need to ask more probing questions to determine the characteristics of the particular symptom and any other associated symptoms. Returning
to the acetaminophen example, if the patient states that the medication is for him andthat he needs it for pain, you will need to ask a few more questions. These questions
might include the following:“Where is the pain located?”“How long has the pain been going on?”“When did the pain start?”“Is the pain radiating to anywhere else?”“Does anything make the pain better or worse?”“What have you tried for the pain already? How much did it help?”“On a scale of 1 to 10, with 1 being the least pain and 10 being the worst pain,
how would you rate your pain?”
These questions should be asked one by one and altered depending on the patient’s
answer.
Additionally, you are also responsible for understanding the disease process of thesymptom and what pertinent positives and negatives you need to assess. For example,
if the patient states that his pain is in his head, you need to know the questions to ask
to either rule in or rule out a headache due to a migraine. Appropriate questions inthis situation could include, but are not limited to, “Do you have any sensitivity tolight?” and “Do you have any other symptoms, such as nausea?”
You will also need to determine other patient-specific factors, such as age, sex,
weight (especially for a child), PMH, allergies, pregnancy status, and breastfeeding
status. Keep in mind that collecting information for all of these factors is not necessary for every patient or every complaint; however, one has to have the knowledge todetermine which factors are pertinent to collect in each specific situation.

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After asking all of the questions to assess the patient’s self-care complaint, youneed to determine the next course of action for your patient. The QuEST mnemonic
includes each part of the self-care counseling process.11 The first part of the mnemonic, Qu, stands for “quickly and accurately assessing the patient.” You may dothis by assessing the seven attributes of a symptom, as discussed in the HPI section.
­Similarly the SCHOLAR method is also used to obtain more detail about the patient’s
complaint. The mnemonic stands for symptoms, characteristics, history, onset, location, aggravating factors, and remitting factors.
The next letter in QuEST, E, stands for “establish that the patient is an appropriate self-care candidate.” This occurs by utilizing the information the patient has given
you and combining it with your own knowledge about disease state management. For
example, if a patient has asthma and is complaining of a cold that is causing shortnessof breath, you should establish that this patient is a candidate for self-care.
The S stands for “suggest appropriate self-care strategies.” Once it has been
determined that the patient is a self-care candidate, meaning that the patient will beable to treat the condition completely or at least partly without a referral to another
healthcare provider, self-care strategies should be formulated.
The T stands for “talk with the patient.” As obvious as this may seem, it is an
important step to recognize, because talking with the patient actually includes providing comprehensive patient education. Such education will include the self-carestrategy, including both nonpharmacologic and pharmacologic agents; the appropriate dose, frequency, and maximum duration of the drug regimen; how to administerand store the drug; adverse effects and what to do in case they occur; when and how
much relief can be expected; and finally, what the patient should do if the condition
worsens or does not improve. Similar to other patient encounters, the patient’s understanding of the instructions should be assessed and questions from the patient should
be solicited and answered.12 Additionally, regardless of which method you choose toutilize for assessing the patient’s self-care complaint in the community setting, youneed to ensure that you are asking all the pertinent questions, even if they are not in
the mnemonic.

The Patient Interview in the Acute Care Setting
The patient interview in the acute care setting includes the same elements as a comprehensive patient health history and medication history. The difference is in how theinterview is conducted, which will be determined by a few setting- and patient-specificfactors, including the hospital area in which the interview is taking place, such as an
emergency room (ER), a general medicine floor, or an intensive care unit, as well as

The Patient Interview in the Acute Care Setting

the patient’s level of alertness. Therefore, your role in the patient interview process
as well as the patient’s condition will determine how you will be able to conduct theinterview and on which elements you will focus.
In the acute care setting, it is important to tailor the interview based on its purpose.
For example, in the ER the pharmacist’s purpose of performing a medication history
may be to determine whether the cause of the visit to the ER is drug-related. Therefore, you will need to focus on learning all the medications that the patient has taken byasking the patient and/or caregiver or family member about the patient’s medications
as well as by looking at a list of medications that the patient may have brought withhim or her or calling the pharmacy to obtain this information. Depending on the situation, the exact strengths, dosing, and adherence may not be as important if the patient
is in critical condition; however, once the patient has stabilized and is either being sent
home or to another part of the hospital, it may be necessary to complete a thoroughmedication history to ensure that medication errors do not occur. For example, if apatient with a history of asthma arrives at the ER complaining of shortness of breath,
you should ask the patient which medications he or she is currently taking for asthma
as well as determine the patient’s adherence to the regimen. Adherence in this case isimportant because it enables you to assess the possible causes of the asthma exacerbation, including the lack of adherence or improper use of an inhaler. In contrast, if apatient comes to the ER complaining of chest pain, you should not ask whether thepatient has been adherent to her statin therapy or if she is currently smoking, because
although the lack of adherence to a lipid-lowering agent and/or smoking may havecontributed to the patient’s possible heart attack, this would not be the time to addressit. However, once the patient’s chest pain has been addressed and treated, assessments
and counseling about tobacco use and medication adherence should occur.
If the patient is in the intensive care unit, you may need to obtain a complete
medication history to ensure that all of the patient’s medical conditions are being
addressed. However, after the initial comprehensive medication history, which may
be obtained from either a family member or caregiver or by calling the pharmacy,
your interactions with the patient may be more focused on specific patient care measures. For example, if the patient is being given pain medication and is conscious andalert, your interview may focus on further exploring how the patient’s pain is being
managed and what symptoms he or she is experiencing that are related to the pain andthe pain medication.
If the patient is on the general floor of the hospital, your interview will be different
based on the day of hospitalization and your role in the patient’s care. For example, on
the first day the patient is admitted to the hospital, the medical team will have conducted
a comprehensive health history, and it may be your role to complete a comprehensive

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medication history. On subsequent days, you may be interacting with your patient todiscuss ongoing treatments and to address any current complaints. Even if a medication
history is not conducted on the first day of admittance, it is vital that a comprehensive
medication history is obtained and documented at some point during the hospital stay.

Chapter Summary
The patient interview, including the comprehensive health and medication history, isfundamental in providing excellent and accurate patient care. The learning and application of communication skills and techniques will allow for a patient encounter thatis characterized by respect as well as offer you the opportunity to learn about patientspecific problems, thereby making your assessment, plan, and approach uniquely
patient-centered. Additionally, use of a structured approach and framework to obtainall the pertinent information from the patient enables you to rely on a set foundationeven as you direct the conversation according to the unique nuances of each particularpatient. Awareness of the setting in which you are conducting the patient interview
and knowing the purpose of the interview will enable you to gather the information
you need to make an accurate assessment and plan, which is essential to providing
high-quality, patient-centered care.

Take Home Messages• Communication skills are the fundamental link between the pharmacist’s­expertise about drugs and his or her contribution to providing excellent patientcentered care; these communication skills must be learned and developed.
• Utilizing the various structured approaches to obtain information from thepatient allows for you to assure that all the pertinent information has been gathered. Simultaneously, actively listening during the patient interview will give
you the opportunity to learn about patient-specific problems.
• The approach to the patient interview in a community setting may be brief­versus a comprehensive visit that occurs in the ambulatory or acute care setting; however pertinent information must be collected to provide an appropriate
assessment and plan.
• The health history of a patient remains the same regardless of the patient-caresetting; however the differences are in how the interview is conducted, patient-­
specific factors, and setting-specific factors. It is necessary to modify your approachto the patient interview in order to provide appropriate patient care in any setting.

References

Review Questions
1.
2.
3.
4.
5.

What are the components of the comprehensive patient interview?
What are the components of the medication history?
Describe the QuEST/SCHOLAR-MAC method.
What is the difference between a leading question and a probing question?
Describe the differences between conducting a medication history for a patientin the emergency room versus the patient in an intensive care unit versus thepatient on a general medicine floor.

References
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2. Berger BA. Communication skills for pharmacists. 3rd ed. Washington, DC: American Pharmacists
Association; 2009;25–29.
3. Empathy. Available at: http://dictionary.reference.com/browse/empathy. Accessed June 17,
2012.
4. Bickley LS. Bates’ guide to physical examination and history taking. 9th ed. Philadelphia: Lippincott
Williams & Wilkins; 2007;1–95.
5. Kaplan CB, Siegel B, Madill JM, Epstein RM. Communication and the medical interview—
strategies for learning and teaching. J Gen Intern Med. 1997;12(2).
6. ASHP Statement on Pharmaceutical Care. Medication therapy and patient care: Organization and delivery of services-statements. Available at: www.ashp.org/doclibrary/bestpractices/­orgstpharmcare.aspx. Accessed June 3, 2012.
7. Walker HK, Hall WD, Hurst JW, eds. Clinical methods: The history, physical, and laboratory
examinations. 3rd ed. Boston: Butterworths; 1990. Available at: www.ncbi.nlm.nih.gov/books/NBK201/. Accessed February 7, 2013.
8. Guidelines for the early management of adults with ischemic stroke. Available at: http://stroke.ahajournals.org/content/38/5/1655.full#cited-by. Accessed June 3, 2012.
9. Ellington AM, Barnett CW, Johnsson DR, Nykamp D. Current methods used to teach the medication history interview to doctor of pharmacy students. Am J Pharm Educ. 2002;66:103–107.
10. FitzGerald RJ. Medication errors: The importance of an accurate drug history. Br J Clin
­Pharmacol. 2009;67:671–675.
11. Buring SM, Kirby J, Conrad WF. A structured approach for teaching students to counsel selfcare patients. Am J Pharm Educ. 2001;71(1):8.
12. Berardi RR, McDermott JH, Newton GD, et al. Handbook of nonprescription drugs: An interactive
approach to self-care. 14th ed. Washington, DC: American Pharmacists Association; 2004;3–37.

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