Raw material exclusively for cosmetic manufacturing

Botanical Cosmetic Raw Material

LaFrance Powder Koken
PYRUS COMMUNIS(PEAR) FRUIT

LaFrance Koken is a cosmetic raw material made by directly
lyophilizing (Freeze-dried) carefully selected (maturity controlled)
La France fruits from Yamagata Prefecture.

Characteristics
Enhances contraction ofcollagen ﬁbers by ﬁbroblasts

Anti-aging eﬀect

Contains polyphenols, which have anantioxidative eﬀect.

Relaxation eﬀect

Contains the characteristically sweet ﬂavor
of La France pears.

Applications: Creams, soaps, lipsticks, etc.

LaFrance Powder Koken
Anti-aging eﬀect by LaFrance components
8*P<0.05

Collagen gel area ( mm2)

7

As for skin aging, it is known that ﬁbroblasts fromelderly people show a lower gel contraction
during collagen gel contraction evaluation than6

those from young people. It is thus considered

5that the skin tension comes from the power of

*

4

*

3

the ﬁbroblasts pulling the collagen ﬁbers.

*

The experiment shown on the left is collagen gel
contraction evaluation to evaluate the contrac-2tion activity of ﬁbroblasts by adding LaFrance

1Powder suspension to collagen gel mixed withﬁbroblasts.

0Without addition

0.05％

0.1％

Since collagen gel contracted by adding the La

0.5％

France Powder suspension, it is expected that
this product will have a skin sagging prevention
eﬀect.

Antioxidant eﬀect bypolyphenols

From in-house data

Sweet ﬂavor characteristicof LaFrance

μmol Trolox eq/mL

12

LaFrance Powder Koken

La France pulp※

10Ethyl acetate

6.1 ppm

2.4 ppm8

Butyl acetate

6.0 ppm

10.1 ppm

6

Hexyl acetate

11.4 ppm

5.9 ppm

4Butanol

6.5 ppm

12.0 ppm

2Hexanol

1.1 ppm

2.4 ppm

Hexanal

1.6 ppm

2.2 ppm

0

LaFrance Powder

Apple juice

Measurement of DPPH radical elimination activity(antioxidant eﬀect). A higher antioxidant eﬀect thanapple juice, which belongs to the same Rosaceae familyas LaFrance, was observed.

Safety evaluation※Reference: Koki Tobitsuka, Nippon Nogeikagaku Kaishi, 77 (8), 762-767 (2003)

Butyl acetate and hexyl acetate, the major componentsof the sweet ﬂavor of LaFrance, are contained at highconcentrations.

From in-house data

Human repeated insult patch test (HRIPT): Negative

Product No.

Product name

INCI name

Other ingredients

Package

LFP-000

LaFrance Powder
Koken

PYRUS COMMUNIS(PEAR) FRUITCYCLODEXTRIN,SUCROSE
ZEA MAYS (CORN) STARCHELAEIS GUINEENSIS (PALM) OIL

100g

The content in this document is prepared based on documents and experimental data available at the time; however, the content does not comprise a quarantee. Please
note in advance that the content described in this document may be changed depending on the circumstances. All intellectual property rights including copyrights anddesign rights of data described here and related documents belong to Koken Co., Ltd., and any unauthorized reproduction, reprinting or citation is strictly prohibited. Pleaserefer to the MSDS of the product in advance for the safe use of these ingredients. In addition, care should be taken to comply with the laws and regulations related to thePharmaceutical Aﬀairs Law in each country on expressions concerning consumer products.
© 2013-2021 KOKEN CO., LTD. C-1-884-1-01-02

1-4-14 Koraku, Bunkyo-ku, Tokyo 112-0004, Japan Tel: 81-3-3816-3562 Fax: 81-3-3816-3582 E-mail:customer@kokenmpc.co.jp