SAFETY DATA SHEETper OSHA HazCom 2012
Revised Date: March 15, 2017

1. IDENTIFICATION OF THE SUBSTANCE AND OF THE COMPANY
Product name:

Rhodamine 610 Chloride

Product Number:06101

Product use:

For laboratory research purposes

Restrictions on use:

Not for drug or household use

Safety Sheet Supplier:

Oakley, Inc.
4000 Luxottica Place
Mason, OH 45040
USATelephone:(614) 492-5610

Emergency Phone:(614) 674-4846

E-mail address:

info.exciton@luxotticaretail.com
2. HAZARDS IDENTIFICATIONClassification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
Acute toxicity, Oral (Category 4), H302
Serious eye damage (Category 1), H318
Acute aquatic toxicity (Category 3), H402
Chronic aquatic toxicity (Category 3), H412
GHS Label elements, including precautionary statements
Pictogram

Signal word

DangerHazard statement(s)
H302
H318
H412

Harmful if swallowed.
Causes serious eye damage
Harmful to aquatic life with long lasting effects

Precautionary statement(s)
P264
P270
P273
P280
P301 + P312
P305 + P351 + P338
P330
P501

Wash skin thoroughly after handlingDo not eat, drink or smoke when using this product.
Avoid release to the environment
Wear protective gloves / eye protection / face protection
IF SWALLOWED: Call a POISON CENTER or doctor/ physician if you feel unwell.
IF IN EYES: Rinse cautiously with water for several minutes. Remove
Rinse mouth
Dispose of contents/ container to an approved waste disposal plant.

Hazards not otherwise classified or not covered by GHS
None

Oakley, Inc. – Rhodamine 610 Chloride

per OSHA HazCom 2012, 2 of 6

3. COMPOSITION/INFORMATION ON INGREDIENTS
Synonyms:
Formula:Molecular Weight:
CAS-No.:EC-No.:

N-[9-(2-carboxyphenyl)-6-(diethylamino)-3H-xanthen-3-ylidine]-N-ethyl-ethanaminium chloride
9-(2-Carboxyphenyl)-3,6-bis(diethylamino)xanthylium chloride
C28 H31 N2 O3 . Cl
479.02 gm/mol
81-88-9201-383-9

Hazardous components
N-[9-(2-carboxyphenyl)-6-(diethylamino)-3H-xanthen-3-ylidine]-N-ethyl-ethanaminium chloride
Acute Toxicity 4; Eye Damage 1; Aquatic Acute 3; Aquatic Chronic 3
4. FIRST AID MEASURES
If inhaled
If breathed in, move person into fresh air. If not breathing, give artificial respiration.
In case of skin contact
Wash off with soap and plenty of water.
In case of eye contact
Flush eyes with water for 15 minutes as a precaution.
If swallowed
Never give anything by mouth to an unconscious person. Rinse mouth with water.
Most important symptoms and effects, both acute and delayed
No further relevant information available
Indication of any immediate medical attention and special treatment needed
No further relevant information available
5. FIRE-FIGHTING MEASURES
Suitable extinguishing media
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
Special hazards arising from the substance or mixture
Carbon oxides, nitrogen oxides (NOx), Hydrogen chloride gas
Special protective equipment for fire-fighters
Wear self-contained breathing apparatus for fire-fighting if necessary.
6. ACCIDENTAL RELEASE MEASURES
Personal precautions
Wear personal protective equipment. Avoid dust formation. Ensure adequate ventilation. Evacuate personnel to safeareas. Avoid breathing dust.
Environmental precautions
Prevent further leakage of spillage if safe to do so. Do not let product enter drains. Discharge into the environment must
be avoided.
Methods and materials for containment and cleaning up
Sweep up and shovel. Keep in suitable, closed containers for disposal.

Oakley, Inc. – Rhodamine 610 Chloride

per OSHA HazCom 2012, 3 of 6

7. HANDLING AND STORAGE
Precautions for safe handling
Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Further processing of solid materials may resultin the formation of combustible dusts. The potential for combustible dust formation should be taken into consideration
before additional processing occurs. Provide appropriate exhaust ventilation at places where dust is formed.
Conditions for safe storage
Keep container tightly closed in a dry and well-ventilated place. Store in cool place.
8. EXPOSURE CONTROLS / PERSONAL PROTECTION
Contains no substances with occupational exposure limit values.
Hygiene measures and engineering controls
Adequate ventilation and/or containment in accordance with good laboratory practices.
Personal protective equipment
Respiratory protection
Respiratory protection is not required. Where protection from nuisance levels of dusts are desired, use type N95 (US)or type P1 (EN 143) dust masks. Use respirators and components tested and approved under appropriate
government standards such as NIOSH (US) or CEN (EU).
Hand protection
Handle with impermeable gloves. Gloves must be inspected prior to use. Use proper glove removal technique (without
touching glove's outer surface) to avoid skin contact with this product. Dispose of contaminated gloves
after use in accordance with applicable laws and good laboratory practices. Wash and dry hands.
Eye / face protection
Use equipment for eye protection tested and approved under appropriate government standards such asNIOSH (US) or EN 166(EU).
Body protection
Choose body protection in relation to its type, to the concentration and amount of dangerous substances,and to the specific work-place., The type of protective equipment must be selected according to theconcentration and amount of the dangerous substance at the specific workplace.

9. PHYSICAL AND CHEMICAL PROPERTIESa) Appearanceb) Odorc) Odor Thresholdd) pHe) Melting pointf) Initial boiling point and boiling rangeg) Flash pointh) Evaporation ratei) Flammabilityj) Upper/lower flammability or explosive limitsk) Vapor pressurel) Vapor densitym) Relative densityn) Solubilityo) Partition coefficient: n-octanol/waterp) Auto-ignition temperature

Form: crystals or powder
Color: green (crystals) or reddish-violet (powder)No data available
No data available
No data available
210-211 C
No data available
No data available
No data available
No data available
No data available
No data available
No data available
No data available
Soluble in water
No data available
No data available

Oakley, Inc. – Rhodamine 610 Chlorideper OSHA HazCom 2012, 4 of 6q) Decomposition temperaturer) Viscosity

No data available
No data available
10. STABILITY AND REACTIVITYa)b)
c)
d)
e)
f)

Reactivity
Chemical stability
Possibility of hazardous reactions
Conditions to avoid (e.g. static discharge)
Incompatible materials
Hazardous decomposition products

No data available
Stable under recommended storage conditions
No data available
No data available
Strong oxidizing agentsSee Section 5.

11. TOXICOLOGICAL INFORMATION
Acute toxicity
LD50 I.V. Rat: 89.5mg/kg
LD50 Oral – Mouse – 887 mg/kg
LDLO Oral – Rat – 500 mg/kg
Skin corrosion/irritation
Skin (rabbit): no skin irritation
Serious eye damage/eye irritation
Eyes (rabbit): severe eye irritation
Respiratory or skin sensitization
No data available
Germ cell mutagenicity
Ames test S. typhimurium (Histidine revers)
Hamster ovary DNA damage
Carcinogenicity
Carcinogenicity - Rat – Subcutaneous -- Tumorigenic: Equivocal tumorigenic agent by RTECS criteria.
Carcinogenicity - Rat – Subcutaneous -- Tumorigenic: Equivocal tumorigenic agent by RTECS criteria.
Blood: Lymphomas including Hodgkin's disease -- Tumorigenic: Tumors at site or application.
This product is or contains a component that is not classifiable as to its carcinogenicity based on its IARC, ACGIH,NTP, or EPA classification.
IARC: 3 - Group 3: Not classifiable as to its carcinogenicity to humans (9-(2-Carboxyphenyl)-3,6bis(diethylamino)xanthylium chloride)
ACGIH: No component of this product present at levels greater than or equal to 0.1% is identified as acarcinogen or potential carcinogen by ACGIH.
NTP:

No component of this product present at levels greater than or equal to 0.1% is identified as aknown or anticipated carcinogen by NTP.

OSHA: No component of this product present at levels greater than or equal to 0.1% is identified as acarcinogen or potential carcinogen by OSHA.
Reproductive toxicity
Reproductive toxicity - Mouse - Intraperitoneal
Effects on Embryo or Fetus: Fetotoxicity (except death, e.g., stunted fetus).

Oakley, Inc. – Rhodamine 610 Chloride

Routes of Exposure:per OSHA HazCom 2012, 5 of 6

Inhalation, Eye contact, Ingestion, Skin contact.

Specific target organ toxicity - single exposure
No data available
Specific target organ toxicity - repeated exposure
No data available
Aspiration hazard
No data available
Signs and Symptoms of Exposure
To the best of our knowledge, the chemical, physical, and toxicological properties have not been thoroughly
investigated.
Additional Information
RTECS: BP3675000
Symptoms and signs of poisoning are: burning sensation, cough, wheezing, laryngitis, Shortness of breath,
Headache, Nausea, Vomiting
12. ECOLOGICAL INFORMATION
Toxicity
Toxicity to fish

LC50 - Cyprinodon variegatus (sheepshead minnow) - 83.9 mg/l - 96 h
LC50 - Lepomis macrochirus (Bluegill) - 379 mg/l - 96 h
LC50 - Oncorhynchus mykiss (rainbow trout) - 217 mg/l - 96 h
Toxicity to daphnia and other aquatic invertebrates

Persistence and degradability
Biodegradability Result:
0 % - not rapidly biodegradable(OECD Test Guideline 302)
Bioaccumulative potential
Bioaccumulation

Cyprinus carpio (Carp) - 24 d
- 0.1 mg/l
Bioconcentration factor (BCF): < 0.2Mobility in soil
No data available
PBT and vPvB assessment
No data available
Other adverse effects
No data available.
13. DISPOSAL CONSIDERATIONS
ProductOffer surplus and non-recyclable solutions to a licensed disposal company.
Contaminated packaging
Dispose of as unused product.
14. TRANSPORT INFORMATION
DOT (US)Not dangerous goods

Oakley, Inc. – Rhodamine 610 Chloride

per OSHA HazCom 2012, 6 of 6IMDG
Not dangerous goods
IATA
Not dangerous goods
15. REGULATORY INFORMATIONSARA 302 Components
SARA 302: No chemicals in this material are subject to the reporting requirements of SARA Title III, Section 302.
SARA 313 Components
SARA 313: This material does not contain any chemical components with known CAS numbers that exceed thethreshold (de Minimis) reporting levels established by SARA Title III, Section 313.
SARA 311/312 Hazards
Acute health hazard.
Massachusetts Right To Know Components
9-(2-Carboxyphenyl)-3,6-bis(diethylamino)xanthylium chloride

CASRN 81-88-9

Pennsylvania Right To Know Components
9-(2-Carboxyphenyl)-3,6-bis(diethylamino)xanthylium chloride

CASRN 81-88-9

New Jersey Right To Know Components
9-(2-Carboxyphenyl)-3,6-bis(diethylamino)xanthylium chloride

CASRN 81-88-9

California Prop. 65 Components
WARNING! This product contains a chemical known to the State of California to cause cancer
9-(2-Carboxyphenyl)-3,6-bis(diethylamino)xanthylium chloride
CASRN 81-88-9
16. OTHER INFORMATIONHMIS Rating
Health hazard:
Chronic Health Hazard:
Flammability:
Physical Hazard:
NFPA Rating
Health hazard:
Fire Hazard:
Reactivity Hazard:

200

200

Further information
Copyright 2017 Oakley, Inc. License granted to make unlimited paper copies for internal use only. The above information
is believed to be correct but does not purport to be all inclusive and shall be used only as a guide. The information in thisdocument is based on the present state of our knowledge and is applicable to the product with regard to appropriate
safety precautions. It does not represent any guarantee of the properties of the product. Oakley, Inc. shall not be held
liable for any damage resulting from handling or from contact with the above product.
Revised Date: March 15, 2017