FMRE-1
Made in JapanTo recover hair growth cycle

FUJI MULBERRY ROOT EXTRACT
For hair growth tonic

Raw material© 2016 Fuji Sangyo Co.,Ltd.

FMRE-2

What is MULBERRY ROOT EXTRACT ?
・MULBERRY ROOT EXTRACT has been used in traditional Chinese medicine forA.the prevention of hypertention
B.Relieving fatigue
C.Tonic property
・It is recently used in cosmetics for whitening effectiveness.

FUJI MULBERRY ROOT EXTRACT
As a result of having tried various extraction method, We found its new effect !
FUJI MULBERRY ROOT EXTRACT recovers hair growth cycle, which causes improvement ofthinning hair.
General MULBERRY ROOT EXTRACT

70% ethanol extraction
FUJI extracting method

MULBERRY
ROOT BARK

Cosmetics for whitening

FUJI
MULBERRY ROOT EXTRACT

Active ingredients in FUJI MULBERRY ROOT EXTRACT
FUJI MULBERRY ROOT EXTRACT includes β-tocopherol that has been confirmed by the test as one of
the active ingredients to recover hair growth cycle.

β-tocopherol
Moreover we assume that there should be more than 2 other effective ingredients in it but unfortunately we have notbeen able to find them out at this moment.

Clinical efficacy
Main hospital : Kochi Red Cross Hospital etc.
Number : Male 55, Female 13

Subject : Male and female pattern alopecia

Length : 3～9 months

Dose : Twice a day ( For a dose : 2mL )12.7%(7/55)

47.3%(26/55)

Male pattern alopecia
60.0% (33/55)
improved

Prominent improvement
Improvement

38.5%(5/13)

15.4%(2/13)

Female pattern alopecia
53.8% ( 7/13)
improved© 2016 Fuji Sangyo Co.,Ltd.

17.6%(12/68)

41.2%(28/68)

Total
58.8% (40/68)
improved

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Prominent improvement of the human clinical test
Prominent improvement is defined that more than 50% of thinning hair is improved comparing with before
testing.
These are the pictures of the prominent improvement of the human clinical test.

Age39 male

Age56 male

Age63 female

Before treatment

Before treatment

Before treatment

After treatment for 6 months

After treatment for 4 months

After treatment for 7 months

Age65 female

Age69 female

Age77 female

Before treatment

Before treatment

Before treatment

After treatment for 7 months

After treatment for 7 months

After treatment for 6 months© 2016 Fuji Sangyo Co.,Ltd.

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Material information
Ingredient of FUJI MULBERRY ROOT EXTRACT
MORUS ALBA ROOT EXTRACT

ALCOHOL

WATER

AspectVerification test

Yellow brown colored and transparent liquidwith peculiar smell.
Metallic taste.

Flavonoids
The liquid presents
blight red～redpH

Value of merit
Specific gravity

4.0～5.9

d 20 0.82～0.92

Triterpenoid

Mulberry Root Extract

Interface presents
dark reddish-brown

The neighborhood of 0.28(yellow～yellowish-brown)
The neighborhood of 0.35(yellow～yellowish-brown)
The neighborhood of 0.38(yellow～yellowish-brown)

Purity test
Heavy metals

Alcohol number

20More than 7.5

Max. 10ppm

Arsenic
Max. 2ppm

Residue on evaporation

Residue on ignition

Component content
Extractive content n-hexaneextract

SanggenonC content

1.0～1.2%

Max. 0.1%

12～36%

0.16～0.50mg/mL

Product name

Aspect

FUJI MULBERRY ROOT EXTRACT

Liquid40 degrees C for 6 months, room temperature for 3 years －Preserve the quality

For storage : You should store it in the bottle with airtight stopper in a cool and dark place and keep it away from fire and heat resource.

Caution when creating the mixture
Formulation of FUJI MULBERRY ROOT EXTRACT
Alcohol: 69.23%, Water: 29.67%, and solid content Mulberry root extract: 1.1%
Recommended dosage
30% (solid content mulberry root extract: 0.33%)
Caution when creating the mixture
The extract is dissolved in a solution of at least 70% alcohol.
The alcohol concentration of the end product must be kept at least 70%.
The ethanol concentration can be lowered by a solubilizer, but this causes the solution to become bubbly.
The lowest alcohol concentration in which a solubilizer works properly is approximately 50%.
Solubilizers verified by Fuji-Sangyo
1. Polyoxyethylene polyoxypropylene decyltetra decylether(trade name: NIKKOL PEN4612 :Nikko Chemicals Co., Ltd.)INCI: PPG-6-DECYLTETRADECETH-12This is a highly safe solubilizer that does not create too many bubbles.
When 30% of a solution is mulberry root extract and the ethanol concentration is 50%,
the extract can be dissolved when a 0.5% solubilizer is added.
2.Polyoxyethylene hydrogenated castor oil(trade name: NIKKOL HCO-50 or HCO-40:Nikko Chemicals Co., Ltd.)INCI: PEG-50 HYDROGENATED CASTOR OIL
INCI: PEG-40 HYDROGENATED CASTOR OIL
This is a highly safe solubilizer. It is used in pharmaceutical drink products, eye drops,and injection solutions. However, it tends to create more bubbles than solubilizer 1 above.
When 30% of a solution is mulberry root extract with an ethanol concentration of 50%,
the extract can be dissolved when a 0.7% solubilizer is added.
Manufacturer

FUJI SANGYO Co., Ltd.
1301 Tamura-cho,Marugame-shi,Kagawa 763-8603 JAPANURL: http://www.fuji-sangyo.co.jp/english/E-mail: mori@fuji-sangyo.co.jp© 2016 Fuji Sangyo Co.,Ltd.