● このスライドは、非営利かつ個人的な目的に限り閲覧することができます。
The following presentation slides are shared with symposium participants exclusively for personal, non-commercial,educational purposes.

● このスライドの著作権は、講演の発表者本人に帰属します（図表等の引用箇所は除く）。如何なる国・地域においても、また紙媒体やインターネット・電子データなど形態に関わらず、スライドの全部または一部を無断で複製、転載、配布、送信、放送、貸与、翻訳、販売、変造、二次的著作物を作成すること等は、固く禁止します。
Copyright of these slides belongs to the presenter and/or the Radiation Medical Science Center for the Fukushima
Health Management Survey, Fukushima Medical University (except figures, tables, etc., cited from other sources).
It is strictly prohibited to reproduce, reprint, distribute, transmit, broadcast, loan, translate, sell, modify, and/or
create derivatives of any slides, in any physical or electronic medium anywhere in the world.

2024年 福島県立医科大学『県民健康調査』国際シンポジウム
公立大学法人福島県立医科大学放射線医学県民健康管理センター
国際シンポジウム事務局（広報・国際連携室）✉ kenkani@fmu.ac.jp Tel: 024-581-5454(平日9～17時)
2024 Fukushima Medical University International Symposium on the Fukushima Health Management Survey
Secretariat of International Symposium
Office of Public Communications and International Cooperation, Radiation Medical Science Center for the Fukushima Health Management Survey, Fukushima Medical University✉ kenkani@fmu.ac.jp, TEL: +81-24-581-5454 (Weekday, 9a.m. - 5 p.m. JST)The Current Status of the Thyroid UltrasoundExamination and Scientific Findings

Fumihiko FURUYA
Department of Thyroid and Endocrinology,
Department of Thyroid Ultrasound Examination,
Radiation Medical Science Centerfor the Fukushima Health Management Survey,
Fukushima Medical University

COI Disclosures

Nothing to discloseTopics
Current progress of the Thyroid Ultrasound Examination (TUE) in theFukushima Health Management Survey
Findings of TUE1
Association between radiation exposure and detection rate of thyroidcancer
Findings of TUE2
Confounding factors other than radiation associated with the detection
rate of thyroid cancer
Current Status and Future of the TUE

Structure and function of thyroid glandFlow chart of Thyroid Ultrasound Examination （TUE) program

malignancy

Outline of TUE

Summary of TUE results
Surveyfor 30

Association between radiation exposureand detection rate of thyroid cancer

Estimation of personal internal exposure
dose (thyroid equivalent dose)
1. As internal exposure doses, thyroid equivalent doses (mSv) exposed fromtap water + inhalation for 14 days after the nuclear power plant accident
were estimated based on the detailed version of behavior report in theBasic Survey form from March 12 to March 25, 2011.
2. External exposure doses were calculated by multiplying the doses assessedin the Basic Survey by the correction factor of 1.1.
3. Cases were those with nodules cytologically diagnosed as malignant or
suspicious for malignancy in the first- to fourth-round surveys, the survey
for 25 years (born in from FY1992 to FY1994 ), and cases of those in theCancer Registry with a year of diagnosis from 2012 to 2018 who have
behavior records in the “Basic Survey.”4. Controls with behavior records were matched to cases by sex, year of birth,malignancy or suspicion of malignancy through participation in all
corresponding rounds leading to the diagnosis (or corresponding year of
diagnosis in the Cancer Registry), it would be the year of diagnosis as to
the respective round), and were randomly selected at a ratio of 1:3 cases
to controls.

Characteristics of cases and controls in the case-control study(Cases were selected in TUE and National Cancer Registry)

Cases (M or SM) (n)Controls (n)Age at the earthquake (mean)

Cases

Controls

Total

153

0153

0459

459

12.9

12.9

12.9

2.3

2.1

2.1

Thyroid equivalent dose (mSv)
MedianMin – Max

Grade B or C (%)

0.11–22.70 0.10 – 21.84

96.1

1.7

0.10 – 22.70

25.3

Document 3-7 in the 20th Thyroid Examination Evaluation Subcommittee

Odds ratio for detection of nodules diagnosed as malignant orsuspicious for malignancy in each thyroid equivalent dose groupcases selected in TUE andNational Cancer Registry

Document 3-7 in the 20th Thyroid Examination Evaluation Subcommittee

There is no statistical dose-response relationshipbetween the "detection rate of nodules diagnosed as
malignant or suspected malignant" and “radiationdose.”Confounding factors other than radiation associatedwith the detection rate of thyroid cancer

Document in the 31st Prefectural Oversight Committee Meeting

Document in the 20th Thyroid Examination Evaluation Subcommittee

Document in the 31st Prefectural Oversight Committee Meeting

Document in the 20th Thyroid Examination Evaluation Subcommittee

Detection rate of nodules diagnosed as
malignant or suspicious for malignancy

Document in the 16th Thyroid Examination Evaluation Subcommittee

Association between gender and thyroid cancer

Document in the 27th, 31st, and 42nd, Prefectural Oversight Committee Meeting and the 16th Thyroid Examination Evaluation Subcommittee

Association between obesity and thyroid cancer

Conclusion
1. The relationship between radiation exposure
dose and Thyroid cancer.
There are no statistically significant doseresponse relationship between radiation doseand the detection rate of thyroid cancer.
2. Confounding factors associated with the thyroidcancer.
Regional differences in the participation rateof confirmatory examination, age, gender, andobesity might be confounding factors which
affects to the detection rate of thyroid cancer.

Current Status and Future of the TUE

1. Development of environment of TUE
Public facilities (evenings and holidays)
Available for application via web and callcenterMedical institutions (85 in-prefecture, 146
out-of-prefecture)*

Public facilities of TUE* Counted as of December 31, 2023

2. Supporting activities
Psychosocial support
Doctors provide detailed explanations at public facilities of primary examination.
A support team offers psychosocial support to participants of the confirmatory
examination to ease their worries and anxiety.

Medical consultation line
Doctors provide telephone consultations.

Interview by support teamOn-site lectures and session
306 sites in total between 2013 and 2023 ** June 30, 2023

Medical expense support from Fukushima Prefecture
Support for the financial burden of medical expenses following a thyroid test

Acknowledgementｓ
Fukushima medical university
Radiation Medical Science Center

Seiji Yasumura
Hitoshi Ohto
Tetsuya Ohira
Masanori Nagao
Fumikazu Hayashi
Hiroki Shimura
Satoru Suzuki
Susumu Yokoya
All Dept. of TUE staff
Department of Thyroid and EndocrinologyRadiation Medical Science Center

Satoshi Suzuki
Yoshiko Matsumoto
Koki Shio

Doctors and medical technologists cooperating with the TUE program● このスライドは、非営利かつ個人的な目的に限り閲覧することができます。
The following presentation slides are shared with symposium participants exclusively for personal, non-commercial,educational purposes.

● このスライドの著作権は、講演の発表者本人に帰属します（図表等の引用箇所は除く）。如何なる国・地域においても、また紙媒体やインターネット・電子データなど形態に関わらず、スライドの全部または一部を無断で複製、転載、配布、送信、放送、貸与、翻訳、販売、変造、二次的著作物を作成すること等は、固く禁止します。
Copyright of these slides belongs to the presenter and/or the Radiation Medical Science Center for the FukushimaHealth Management Survey, Fukushima Medical University (except figures, tables, etc., cited from other sources).
It is strictly prohibited to reproduce, reprint, distribute, transmit, broadcast, loan, translate, sell, modify, and/or
create derivatives of any slides, in any physical or electronic medium anywhere in the world.

2024年 福島県立医科大学『県民健康調査』国際シンポジウム
公立大学法人福島県立医科大学放射線医学県民健康管理センター
国際シンポジウム事務局（広報・国際連携室）✉ kenkani@fmu.ac.jp Tel: 024-581-5454(平日9～17時)
2024 Fukushima Medical University International Symposium on the Fukushima Health Management Survey
Secretariat of International Symposium
Office of Public Communications and International Cooperation, Radiation Medical Science Center for the Fukushima Health Management Survey, Fukushima Medical University✉ kenkani@fmu.ac.jp, TEL: +81-24-581-5454 (Weekday, 9a.m. - 5 p.m. JST)