protein
GAPDH

100

Pit
Br
uit
ain
aryglaHi
ppndoc
am
pus
Ca
udaCe
re b t eellum
ReTh
tin
yroa
id
gla
ndAppen
Lydix
mp
hnode
To
ns
il
Sp
leenTh
ym
He
us
art
Sk
mu
ele
sc
letal
mu
Sm
sc
oo
leth
mu
sc
leLungGa Liverllb
laddePar
nc
Sar
ea
livs
ary
gla
Esnd
op
Sm
hagu
alls
int
es
tin
e
Co
lon
Ur
Kid
ina
ne
ryybladder
TestisPr
ostat
EpeidiSedym
mina
islvesi cleBreastVaCeginrviax,uteEnrin
doemetriumOvaP l a ryAdceipontasetissue0

精巣で機能している修復タンパク質
g-H2AXSCP3Repair
Protein /g-H2AX
Spermatocyte DAPImarker

Repair Protein / Spermatocyte marker

GENE INFORMATIONi

Gene name

KAT7 (HGNC Symbol)

Synonyms

HBO1, HBOA, MYST2, ZC2HC7

RNA tissue category: Expressed in all
FANTOM5 dataset
Lysine acetyltransferase 7 (HGNC Symbol)
Tags PerMillion
Tags Per Million The protein encoded by this gene is part of the multimeric HBO1 complex, which possesses histone H4-specific acetyltransferase activity. ThisL iv

400
Entrez genesummary

activity is required for functional replication origins and is involved in transcriptional activation of some genes. In both cases, the acetylation of

Chromosome
300

17

Cytobandq21.33Chromosome
200
location (bp)49788555 - 49835030

Protein evidence

Evidence at protein level (all genes)

Ensembl1000

neXtProt

Antibodypedia

g-H2AXENSG00000136504 (version 88.38)
11143

Entrez gene
UniProt

histone H4 helps unfold chromatin so that the DNA can be accessed and replicated or transcribed. [provided by RefSeq, Oct 2016]

O95251 (UniProt - Evidence at protein level)

PitBruit
aina rygla
Hi
ppndoc
ampus
Ca
udaCe
reb teellum
ReThtinyroaidgla
ndAppend
Lyix
mp
hnodeTo
nsil
Sp
leenTh
yHe
mu
arts
Sk
mu
ele
sc
letal
mu
Sm
sc
oolethmu
sc
leLungGa Liverllb
laddeParnc
Sa
realivsa ry
gla
EsndopSmhagu
allsintestineColonUrKidina
neryybladder
Testis
ProstatEpeidi
Sedymiminaslv
esicleBr
eastVaCeginrvi
ax,uterEn
inedometriumOvaPla ryAd
ceipo
nta
se
tissueRepairproteinGAPDHerBrai
Ki ndneLu yng
Tes tisDescription

NX_O95251

KAT7 antibodies

SCP3 g-H2AX DAPIPROTEIN BROWSERi

Repair Protein / Spermatocyte marker

Repair Protein / Spermatocyte marker

GENE INFORMATIONi

KAT7-001 KAT7-002 KAT7-003 KAT7-004 KAT7-006 KAT7-008 KAT7-014
Gene name
KAT7 (HGNC Symbol)
Synonyms

HBO1, HBOA, MYST2, ZC2HC7

Description

Lysine acetyltransferase 7 (HGNC Symbol)

Entrez genesummary

10 w testis

The protein encoded by this gene is part of the multimeric HBO1 complex, which possesses histone H4-specific acetyltransferase activity. This
activity is required for functional replication origins and is involved in transcriptional activation of some genes. In both cases, the acetylation ofhistone H4 helps unfold chromatin so that the DNA can be accessed and replicated or transcribed. [provided by RefSeq, Oct 2016]

Chromosome

17Cytoband

q21.33Chromosome
location (bp)49788555 - 49835030

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000136504 (version 88.38)

Entrez gene

11143

UniProt

O95251 (UniProt - Evidence at protein level)

neXtProt

NX_O95251

Antibodypedia

KAT7 antibodies

PROTEIN BROWSERi
PROTEIN INFORMATIONi

KAT7-001 KAT7-002 KAT7-003 KAT7-004 KAT7-006 KAT7-008 KAT7-014

Splice variant

UniProt

Protein class
EnzymesO95251 [Direct mapping]

ENSP00000413415 Histone acetyltransferase
ENST00000454930

KAT7

Length &mass

SignalTransmembrane
peptideregions(predicted) (predicted)

10 w testis

GO:0000123 [histone acetyltransferase complex]
GO:0003700 [transcription factor activity, sequencespecific DNA binding]
GO:0004402 [histone acetyltransferase activity]
GO:0005515 [protein binding]Zinc-coordinating DNA-binding domains GO:0005634 [nucleus]
Show allShow allProtein evidence (Kim et al 2014)
GO:0005654 [nucleoplasm]
Enzymes
GO:0000123 [histone acetyltransferase complex]
ENZYME proteinsGO:0003700 [transcription factor activity, sequenceTransferases
specific DNA binding]Predicted intracellular proteins
GO:0004402 [histone acetyltransferase activity]
Transcription factors
GO:0005515 [protein binding]

ENZYME proteins
KAT7-001
O95251 [Direct mapping]Transferases
ENSP00000259021 Histone acetyltransferase Predicted intracellular proteins
KAT7
Transcription factors
ENST00000259021

KAT7-002

Gene ontology

611 aa70.6 kDa

No

C57BL/6 : 10w
472 aa55.1 kDa

No00