SAFETY DATA SHEETSDS No.5010-0193

DateDecember 24, 2019

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1. PRODUCT AND COMPANY IDENTIFICATIONPRODUCT NAME
： InertSep GC/SAX/PSA
NAME OF SUPPLIER： GL Sciences Inc.
ADDRESS： 22-1 Nishishinjuku 6-chome Shinjuku-ku Tokyo 163-1130, JapanCHARGE SECTION： International Sales Section
TELEPHONE No.
： +81-3-5323-6620
FACSIMILE No.
： +81-3-5323-6621
PRODUCT No.
： 5010-68044, 5010-68045, 5010SDS No.
： 5010-0193
Research use only.
2. HAZARDS IDENTIFICATIONGHS CLASSIFICATION：Serious eye damage/eye irritationHAZARDS SYMBOL：： Category 2BSpecific target organ toxicity (single exposure)： Category 3(Respiratory tract irritancy)

SIGNAL WORD
： Warning
HAZARD STATEMENTS：
H320
Cause eye irritation
H335
May cause respiratory irritation
PRECAUTIONARY STATEMENTS ：P261
Avoid breathing dust/fume/gas/mist/vapours/spray.
P264
Wash hands thoroughly after handling.
P271
Use only outdoors or in a well-ventilated area.
P304+P340
IF INHALED: Remove person to fresh air and keep comfortable for breathing.
P305+P351+P338
IF IN EYES: Rinse cautiously with water for several minutes. Remove contactlenses, if present and easy to do. Continue rinsing.
P312
Call a POISON CENTER or doctor if you feel unwell.
P337+P313
If eye irritation persists: Get medical attention.
P403+P233
Store in a well-ventilated place. Keep container tightly closed.
P405
Store locked up.
P501
Dispose of contents/container in accordance with all applicable regulations.
3. COMPOSITION/INFORMATION ON INGREDIENTSCHEMICAL IDENTITY： Mixture
This product is a combination of a single component.
CONTENTCHEMICAL FORMULA

CAS RNTSCAINVENTRY

EINECS
No.

Graphite carbon black

100%C

1333-86-4

Listed215-609-9

Trimethylaminopropylgroup modified silica gel

100%-(SiO2 )-(CH 2) 3N＋(CH3 )3112926-00-8--

Ethylenediamine-N-propylgroup modified silica gel

100%(SiO 2)-(CH2 )3 NH(CH 2 )2NH2112926-00-8--

CHEMICAL NAME

PRODUCT NAME ： InertSep GC/SAX/PSASDS No.5010-0193
4. FIRST AID MEASURES
GENERAL ADVICEINHALATIONSKIN CONTACTEYE CONTACTINGESTION

DateDecember 24, 2019

2/5 page： Wash off immediately with soap and plenty of water. In the case of respirable
dust and/or fumes, use self-contained breathing apparatus and dust
impervious protective suit. Use personal protective equipment.
： Move victim to fresh air and gargle. If breathing is difficult, give oxygen.
If irritation persists, consult a physician.
： Remove contaminated clothes and shoes, rinse skin with plenty of water orshower. Use soap to help assure removal. If irritation persists, consult aphysician.
： Remove any contact lenses at once. Flush eyes well with flooding large
amounts of running water for at least 15 minutes. Assure adequate flushing byseparating the eyelids with sterile fingers. If irritation persists, consult aphysician.
： Rinse mouth, give plenty of water to vomit. Never give anything by mouth to an
unconscious person. Consult a physician.

5. FIRE FIGHTING MEASURES
EXTINGUISHING MEDIA
FIRE & EXPLOSION HAZARDS： Carbon dioxide, dry chemical powder, foam, water spray： CO 2 , CO are included in a flue gas. Use cylinder-type air respiratory apparatus
at the fire extinguishing in the room.
Pay attention to shatter-resistant this product.
SPECIAL PROTECTIVE EQUIPMENT FOR FIRE FIGHTERS： Fireman should wear normal protective equipment (full bunker gear) andpositive-pressure self-contained breathing apparatus.

6. ACCIDENTAL RELEASE MEASURESPERSONAL PRECAUTIONS： Remove ignition sources and ventilate the area. In case of insufficientventilation, wear suitable respiratory equipment. Avoid raising dust and avoid
contact with skin and eyes.
ENVIRONMENTAL PRECAUTIONS： Prevent spills from entering sewers, watercourses or low areas.
Comply with local disposal regulations.
METHODS FOR CLEANING UP： Do not touch spilled material without suitable protection. After material iscompletely picked up, wash the spill site with soap and water and ventilate thearea. Pull all wastes in a plastic bag for disposal and seal it tightly. Remove,clean, or dispose contaminated clothing.
7. HANDLING AND STORAGE
HANDLING
STORAGEINCOMPATIBLE PRODUCTS： Avoid contact with eyes, skin, and clothing. Avoid prolonged or repeatedexposure. Handle this product with appropriate protective equipment.
： Store it in a refrigerator (2-10 °C)
Keep container tightly closed.
： Oxidizers and acidsPRODUCT NAME ： InertSep GC/SAX/PSASDS No.5010-0193

Date

December 24, 2019

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8. EXPOSURE CONTROL/PERSONAL PROTECTION
ENGINEERING MEASURES： Use exhaust ventilation to keep airborne concentrations below exposure limits.
Use adequate ventilation.
VENTILATION： Local Exhaust ; Necessary, Mechanical(General) ; Recommended
CONTROL PARAMETERS
Chemical name(or common name)

ACGIH TLVOSHA PELNIOSH REL

Graphite carbon black

TWA=3.5mg/m3

TWA=3.5mg/m3

TWA=3.5mg/m3

Trimethylaminopropyl group
modified silica gel

Inhalable dust
TWA=10mg/m3,Respirable dust
TWA=3mg/m3(as PNOS)

80mg/m3/%SiO2(as amorphous silica)

TWA=6mg/m3(as amorphous silica)

Ethylenediamine-N-propylgroup modified silica gel
PERSONAL PROTECTIONRESPIRATORY PROTECTION
HAND PROTECTION
EYE PROTECTION
SKIN PROTECTION： Half or full face piece respirator, self-contained breathing apparatus, supplied
air respirator, etc. Use respirators approved under appropriate government
standards and follow all regulations.
： Safety gloves： Safety glasses(goggles)： Protective clothing

9. PHYSICAL AND CHEMICAL PROPERTIESPHYSICAL STATE： Solid (powder)
COLOUR： Black (GC)/White(SAX&PSA)
ODOUR： Odourless
MELTING POINT / FREEZING POINT： > =3000 °C (GC)/No data available(SAX&PSA)
BOILING POINT OR INITIAL BOILING POINT AND BOILING RANGE： > =3000 °C (GC)/No data available(SAX&PSA)
FLAMMABILITY： Non Flammable
LOWER AND UPPER EXPLOSION LIMIT / FLAMMABILITY LIMIT： Not applicable
FLASH POINT： No data available
AUTO-IGNITION TEMPERATURE ： No data available
DECOMPOSITION TEMPERATURE： No data available
pH： No data available
KINEMATIC VISCOSITY： Not applicable
SOLUBILITY IN
Water： Insoluble
Organic solvent： Insoluble
PARTITION COEFFICIENT
n-octanol/water (log value)： No data available
VAPOUR PRESSURE： No data available
DENSITY AND/OR RELATIVE DENSITY： No data available
RELATIVE VAPOUR DENSITY： Not applicable
PARTICLE CHARACTERISTICS ： No data available

PRODUCT NAME ： InertSep GC/SAX/PSASDS No.5010-0193

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10. STABILITY AND REACTIVITY
REACTIVITY： Stable under recommended using and storage conditions.
CHEMICAL STABILITY： Stable under recommended storage and using conditions.
CONDITION TO AVOID： Sunlight, heat, moisture, CO 2 , oxidizers, acids
INCOMPATIBILE MATERIALS： Oxidizers, acids
HAZARDOUS DECOMPOSITION PRODUCTS： CO, CO 2
11. TOXICOLOGICAL INFORMATIONACUTE TOXICITY：(GC)： LD0 value of >8000 mg/kg bw for rats (IUCLID (2000))
LD50 value is >3 mg/kg for rabbits (RTECS (2008)(SAX&PSA)： Not classified (oral, dermal)
Classification not possible, No data available (inhalation(dust, mist))
SKIN CORROSION/IRRITATION(GC)： Results of "no irritating" in 4 tests with rabbits (one test was conductedaccording to OECD TG404) (IUCLID (2000)).
(SAX&PSA)： Not classified
EYE DAMAGE/EYE IRRITATION ： Category 2B(GC)： Based on results of "no irritating" in 3 tests with rabbits (IUCLID (2002)), thesubstance was classified as "Not classified". Although there is a result of"irritating" in a human test (IUCLID (2002)), the details are not clear. It has
been suggested that the fine grain may be irritating mechanically (HSDB(2003)).
SENSITIZATION： Classification not possible, No data available
GERM CELL MUTAGENICITY： Classification not possible(GC)： Although there is a positive result in a rat alveolar cell HPRT gene mutation
test by inhalation exposure and intratracheal administration (in vivo somaticcell mutagenicity test) (DFGOT vol.18 (2002)), this positive result is
considered not to indicate the germ cell mutagenicity of carbon black since it isthought to be induced by the polycyclic aromatic hydrocarbons present in thesubstance or by reactive oxygen species due to inflammation reaction.
CARCINOGENICITY： Classification not possible
Inadequate evidence of carcinogenicity in humans (IARC 68 (1997))(GC)： Based on the classification of "Group 2B" in IARC and Category 2B in Japan
Society For Occupational Health (JSOH), the substance was classified into
Category 2. In a 24-month inhalation test in rats, the incidence of primary lungneoplasms was increased significantly and was dose related The types ofneoplasms were identical and included benign adenomas, malignant
adenocarcinomas,
squamous-cellcarcinomas,
andadenosquamouscarcinomas (EHC No.171 (1996)). In a rat test, the 43-week and 86-week
exposure groups had a lung tumour rate of 18% and 8%, respectively, with notumours observed in the control group (IARC vol.65 (1996)).
IARC in group 2B (IARC 93 (2010)), ACGIH is classified into A3 (ACGIH (7th,2011)), which is based on inhalation experiments by rats.
For humans, epidemiological studies in Europe and the United States havealso been concluded as "inappropriate as evidence to classify carcinogenicity"
due to inadequate methodological deficiencies and lack of number of subjects
to be investigated.
REPRODUCTIVE TOXICITY： Classification not possible, No data available
SPECIFIC TARGET ORGAN TOXICITY - single exposure ： Irritating to respiratory tract (SIDS (2006), ECETOC JACC (2006))(GC)： Although there is a report of behavioral somnolence as a symptom after oral
administration to rats (15,400 mg/kg) (RTECS (2008)), the details are
unknown, therefore, classification was not possible due to lack of sufficientdata.

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SPECIFIC TARGET ORGAN TOXICITY - repeated exposure ： Classification not possible(GC)： Numerous epidemiological tests for carbon black workers were conducted. In
workers exposed for long term (10 years and more), the following symptoms
characteristic of the lung occurred; cough, sputum, chronic bronchitis, lungfunction disturbances, pneumoconiosis, emphysema, disturbance of lungperfusion, obstructive disturbance of ventilation, bronchial hyper-reactivity anddecrease in airway resistance and expiratory flow (IARC vol.65 (1996)). In
addition, it was reported that fine, diffuse changes were observed in the chest
radiogram, and histological examination revealed deposits of carbon black
particles and reticular fibrosis with associated emphysema (IARC vol.65(1996)).
ASPIRATION HAZARD： Classification not possible, No data available
12. ECOLOGICAL INFORMATIONECOTOXICITY(GC)： Not classified： Classified into Not classified since it is suggested not to show the toxicity at
the concentration of water solubility (insoluble (HSDB,2009)) from its
72h-ErC50 >10000 mg/L for algae (Scenedesmus) (SIDS,2006), its 24h-LC50>5600 mg/L for Crustacea (Daphnia magna) (SIDS,2006) and its 96h-LC50>1000 mg/L for fish (Tribolodon hakonensis) (SIDS,2006).
BIODEGRADABILITY： May not occur microbial degradation
BIOACCUMULATIVE POTENTIAL ： No data available
MOBILITY IN SOIL
： No data available
HAZARDOUS TO THE OZONE LAYER： Not listed in Montreal Protocol list.

13. DISPOSAL INFORMATION
Dispose in a hazardous-waste site in accordance with all applicable regulations. Any disposal practice must be incompliance with country, local, state, and federal laws and regulations (contact country, local or state environment
agency for specific rules).
14. TRANSPORT INFORMATION
IATA： Not dangerous goods
ADR/RID： Not dangerous goods
DOT(Department of Transportation)： Not dangerous goods
MARINE POLLUTANT： Not classified
15. REGULATORY INFORMATIONFor classification and labeling of chemicals in accordance with the applicable rules and regulations in the EU or eachcountry, refer to GHS classification of this product (See Section 2).
US REGULATION ：OSHA HCS 2012/29 CFR 1910.1200
EU REGULATION ：CLP Regulation ((EC) No. 1272/2008)
16. OTHER INFORMATIONNOTICE:The information contained in the SDS description is applicable exclusively to the chemical substance identified
herein and for its intended use as an analytical reference standard or reagent and to the unit quantity intended forthat purpose. The information does not relate to, and may not be appropriate for, any application or larger quantityof the substance described. Our products are intended for the use by individuals possessing sufficient technicalskill and qualification on use the material potential hazardous chemical. Accordingly, no representation or warranty,
express or implied, with respect to merchantability and fitness for a particular purpose is made with respect to theinformation contained herein.

Attention:
This product in terms of chemical identity and the unit amount provide is intended for use in chemical analysis andnot for human consumption, nor any other purpose.