3-Y-F1-1 YIA
Oral administration of food-derived amino acid ergothioneine enhanceslearning and memory by phosphorylation of TrkB and promotion ofneurogenesis in the hippocampal dentate gyrusYusuke Matsuo1, Takahiro Ishimoto1, Shunsuke Nakao1, Yusuke Masuo1, Satoshi Matsumoto2,Makoto Suzuki2, Yukio Kato1
1Fac. Pharm., Kanazawa Univ., 2L•S Corporation Co. Ltd.

Copyright © The Japanese Pharmacological Society3-Y-F1-2 YIA
The effects of Ninjinyoeto on spatial memory impairment in a rat model withcerebral ischemia and β-amyloid injection
Masaki Nagao1, Akinobu Hatae2, Kazuma Mine2, Soichiro Tsutsumi2, Marika Hiarata2,Kazuma Matsui2, Hiroya Omori2, Takuya Watanabe1,2, Kaori Kubota1,2, Shutaro Katsurabayashi2,Katsunori Iwasaki1,2
1

Ins. Aging and Brain Sci., Fukuoka Univ., Fukuoka, Japan, 2Dept. Neuropharmacol. Fac. Pharm. Sci. Fukuoka
Univ. Fukuoka, Japan

Copyright © The Japanese Pharmacological Society3-Y-F1-3 YIA
The mice with exonic Reln deletion show cognitive dysfunction but notattention impairment in the touchscreen operant tasks
Geyao Dong1, Taku Nagai1, Jingzhu Liao1, Daisuke Mori2, Bolati Wolar1, Toshitaka Nabeshima3,4,Norio Ozaki2, Kiyofumi Yamada1
1

Department of Neuropsychopharmacology and Hospital Pharmacy, Nagoya University Graduate School ofMedicine, 2Department of Psychiatry, Nagoya University Graduate School of Medicine, 3Advanced Diagnostic
System Research Laboratory Fujita Health University, Graduate School of Health Sciences, 4Aino University

Copyright © The Japanese Pharmacological Society3-Y-F1-4 YIA
The role of voltage-dependent potassium channels in the medial prefrontal
cortex in nicotine-induced enhancement of object recognition memory
Esaki Hirohito1, Shoma Izumi1, Akari Fukao2, Masaki Domoto1, Tong Zhang1, Naoya Nishitani1,2,
Satoshi Deyama1,2, Katsuyuki Kaneda1,2
1Lab. Mol. Pharmacol., Inst. Med., Pharmaceut., Health Sci., Kanazawa Univ., 2Lab. Mol. Pharmacol., Sch.
Pharmaceut. Sci., Kanazawa Univ.

Copyright © The Japanese Pharmacological Society3-Y-F2-1 YIA
Anti-high mobility group box-1 (HMGB1) antibody therapy for spinal cordischemia-reperfusion injury in rabbits
Muraoka Genya1, Keyue Liu2, Handong Qiao2, Daiki Ousaka2, Dengli Wang2, Yasuhiro Fujii1,Shingo Kasahara1, Masahiro Nishibori2
1

Dept. Cardiovascular Surg., Okayama Univ., 2Dept. Pharmacol., Okayama Univ.

Copyright © The Japanese Pharmacological Society3-Y-F2-2 YIA
The identification of neuro-reparative lipids in ischemic stroke
Nakamura Akari1,2, Seiichirou Skai1, Makoto Murakami3, Takashi Shichita1,4
1Tokyo Metropolitan Inst., 2Tokyo Medical and Dental Univ., 3Tokyo Univ., 4Japan Agency for Medical Research andDevelopment

Copyright © The Japanese Pharmacological Society3-Y-F2-3 YIA
TRPA1 plays a protective role in cognitive impairment and white matterinjury in chronic cerebral hypoperfusion
Masashi Kakae, Hiroki Nakajima, Misa Morishima, Shota Tobori, Kazuki Nagayasu,Hisashi Shirakawa, Shuji Kaneko
Dept. Mol. Pharmacol., Grad. Sch. Pharmaceut. Sci., Kyoto Univ.

Copyright © The Japanese Pharmacological Society3-Y-F2-4 YIA
Imaging of water kinetics during cytotoxic edema using indirect MRI with17O -labeled water
Tomoe Ishikawa1, Yutaka Hoshino2, Hiroyuki Kameda2, Yuji Komaki4, Miyuki Unekawa3,Yutaka Tomita3, Jin Nakahara3, Kohsuke Kudo2, Masato Yasui1
1Dept., Pharmacol., Sch., Med., Keio Univ., 2Dept., Radiol., Hokkaido Univ Hosp., 3Dept., Neurol., Sch., Med., Keio
Univ., 4Central., Inst., Exp., Anim.

Copyright © The Japanese Pharmacological Society3-Y-F3-1

YIA
18

Development of Brain Molecular PET Imaging with a F-labeled Small
Protein Affinity Ligand
Takahiro Morito1, Ryuichi Harada1,2, Ren Iwata3, Yiqing Du1, Nobuyuki Okamura4,Yukitsuka Kudo2, Kazuhiko Yanai1,31

Dept. Pharmacol., Tohoku Univ. Grad. Sch. Med., 2Dept. Gerontol. Geriatrics, Tohoku Univ., 3CYRIC, Tohoku
Univ., 4Div. Pharmacol., Fac. Med., Tohoku Med. Pharmaceut. Univ.

Copyright © The Japanese Pharmacological Society3-Y-F3-2

YIA
18

Characterization of a novel monoamine oxidase-B tracer [ F]SMBT-1 forimaging of reactive astrocytes
Yiqing Du1, Ryuichi Harada1,2, Yu Akaida3, Takahiro Morito1, Hiroyuki Arai2, Mari Yoshida4,Yukitsuka Kudo2, Shozo Furumoto3, Nobuyuki Okamura5, Kazuhiko Yanai1
1Dept. Pharmacol., Grad. Sch. Med., Tohoku Univ., 2Dept. Geriatrics and Gerontology, Div. Brain Science, Inst.
Development, Aging and Cancer, Tohoku Univ.,3Cyclotron and Radioisotope Ctr., Tohoku Univ.,4Inst.
Development, Aging and Cancer, Aichi Medical Univ.,5Div. Pharmacol., Fac. Med., Tohoku Medical andPharmaceutical Univ.

Copyright © The Japanese Pharmacological Society3-Y-F3-3 YIA
A novel method of long-lasting single-particle tracking based onregenerative fluorescent labeling
Shinkuro Kobayashi, Shigeyuki Namiki, Daisuke Asanuma, Kenzo Hirose
Dept. Pharm., Grad. Sch. Med., the Univ. of Tokyo

Copyright © The Japanese Pharmacological Society3-Y-F3-4 YIA
In vivo fluorescence imaging of extracellular ATP dynamics in brainischemia
Nami Kitajima1, Kenji Takikawa1, Hiroshi Sekiya2, Daisuke Asanuma1, Hirokazu Sakamoto1,Shigeyuki Namiki1, Masamitsu Iino3, Kenzo Hirose1
1

Dept. of Pharmacol., Grad. Sch. of Med., Univ. of Tokyo, 2Dept. of Physiol., Grad. Sch. of Med., Univ. of Tokyo,
3
Dept. of Cell. and Mol. Pharmacol., Nihon Univ. Sch. of Med.

Copyright © The Japanese Pharmacological Society3-Y-G1-1 YIA
Voltage-dependence in ICaL block predicts EAD in drug-induced arrhythmias
Kimura Akira1, Shingo Murakami2
1

Chuo Univ. Grad. Ele., 2Chuo Univ. Grad. Sci.& Eng.

Copyright © The Japanese Pharmacological Society3-Y-G1-2 YIAElectrophysiological analysis of the anti-atrial fibrillatory action ofoseltamivir using the paroxysmal atrial fibrillation canine model
Ryuichi Kambayashi1, Yoshio Nunoi1, Ai Goto1, Yoshiki Hirokawa1, Hiroko Izumi-Nakaseko1,
Mihoko Hagiwara-Nagasawa1, Yoshinori Takei2, Akio Matsumoto3, Shinichi Kawai4,
Atsushi Sugiyama1,2,3,4
1

Dept. Pharmacol., Faculty Med., Toho Univ., 2Dept. Translational Research & Cellular Therapeutics, FacultyMed., Toho Univ., 3Dept. Aging Pharmacol., Faculty Med., Toho Univ., 4Dept. Inflammation & Pain Control
Research, Faculty Med., Toho Univ.

Copyright © The Japanese Pharmacological Society3-Y-G1-3 YIA
Effect of hyperglycemia on the cardiovascular functions in the isofluraneanesthetized intact dogs
Hirokawa Yoshiki1, Ryuichi Kambayashi2, Ai Goto1, Yoshio Nunoi2, Hiroko Izumi-Nakaseko1,2,
Mihoko Hagiwara-Nagasawa2, Yoshinori Takei3, Akio Matsumoto4, Shinichi Kawai5, Jörg Täubel6,Atsushi Sugiyama1,2,3,4,51

Dept. Pharmacol., Grad. Sch. Med., Toho Univ., 2Dept. Pharmacol., Faculty. Med., Toho Univ.,3Dept.
Translational Research & Cellular Therapeutics., Faculty. Med., Toho Univ.,4Dept. Aging Pharmacol., Faculty.
Med., Toho Univ., 5Dept. Inflammation & Pain Control Research, Faculty. Med., Toho Univ.,6Molecular & Clinical
Sciences Research Institute, St George's University of London.

Copyright © The Japanese Pharmacological Society3-Y-G1-4 YIA
Biological sex differences in morphological function of embryonic murine
coronary arteries
Shion Nagasawa1, Masami Kodama2, Kazuho Sakamoto1, Junko Kurokawa1
1Sch. Pharmaceut. Sci, University of Shizuoka, 2IQB, The University of Tokyo

Copyright © The Japanese Pharmacological Society3-Y-G2-1 YIA
TRPC5 channel-Caveolin-1-eNOS signalplexes coordinate interplay between
2+
Ca and NO signals in endothelial cells
Reiko Sakaguchi1,2, Nobuaki Takahashi1,3, Takashi Yoshida1,4, Nozomi Ogawa1, Yoshifumi Ueda1,
Satoshi Hamano1, Kaori Yamaguchi1, Seishiro Sawamura1, Shinichiro Yamamoto1,4, Yuji Hara1,Masayuki Mori1, Tetsushi Furukawa5, Shunichi Shimizu4, Ryuji Inoue6, Yasuo Mori1,21

Department of Engineering, Kyoto Univ, 2iCeMS, Kyoto Univ, 3Hakubi Project, Kyoto Univ, 4Faculty of
Pharmaceutical Sciences, Teikyo Heisei Univ, 5Medical Research Institute, Tokyo Medical and Dental Univ,
6
Department of Physiology, Fukuoka Univ.

Copyright © The Japanese Pharmacological Society3-Y-G2-2 YIA
Acute hypoxia enhances the proliferation of brain capillary endothelial
2+cells via upregulation of Ca -activated Cl channel TMEM16A.
Takahisa Suzuki1, Yoshiaki Suzuki1, Kiyohumi Asai2, Yuji Imaizumi1, Hisao Yamamura1
1Dept. Mol. and Cell. Pharmacol., Grad. Sch. Pharm., Nagoya City Univ., 2Dept. Mol. Neurobiol., Grad. Sch. Med.,
Nagoya City Univ.

Copyright © The Japanese Pharmacological Society3-Y-G2-3 YIA
CAMKII inhibitor as novel cardioprotective agent on doxorubicin
cardiotoxicity
クルニアワン プリヨノ アグン, Junichiro Miake, Youkou Syuu, Katsunori Ichihara, Tatsuya Sawano,
Keiko Nagata, Takeshi Imamura
Tottori University, Medical department, pharmacology

Copyright © The Japanese Pharmacological Society3-Y-G2-4 YIA
Development of high efficient method in human iPS induction from patientderived primary cells.
Tanaka Naomichi, Takaaki SenbonmatsuSaitama medical university international medical center

Copyright © The Japanese Pharmacological Society3-Y-G3-1 YIA
Arginase 1 is involved in lacrimal hyposecretion in male NOD mice.
Yuta Ohno1, Keitaro Satoh1,2, Akiko Shitara1, Haruna Nagase1, Masanori Kashimata1
1

Dept. Pharmacol., Asahi Univ. Sch. Dent., 2Dept. Pharmacol., Meikai Univ. Sch. Dent.

Copyright © The Japanese Pharmacological Society3-Y-G3-2 YIA
Evaluation of primate dental pulp regeneration by quantitative fluorescenceimaging of macrophages
Yu Toida, Takanori Sato, Tadahiro Iimura
Dept Pharmacol, Hokkaido Univ Grad Sch Dent Med

Copyright © The Japanese Pharmacological Society3-Y-G3-3 YIA
Teriparatide improves bone quality through augmenting the linearity of bone
collagen fibers, revealed by novel analysis of nonlinear optics imaging andAI-based morphometrical recognition method
Takanori Sato, Yu Toida, Tadahiro IimuraDept. Pharmocol. Grad. Sch. Dent Med., Hokkaido Univ.

Copyright © The Japanese Pharmacological Society3-Y-G3-42+

YIA2+Ca release-activated Ca channels are involved in osteoarthritic marker
induction by interleukin-1β in mouse chondrocytesRisa Kurose, Yoshiaki Suzuki, Yuji Imaizumi, Hisao Yamamura
Dept. Mol. Cell. Pharmacol., Grad. Sch. Pharmaceut. Sci., Nagoya City Univ.

Copyright © The Japanese Pharmacological Society