1-LBS-01
Oral L-histidine supplementation improves working memory through theactivation of brain histamine system in male mice
Roh Sueji1, Tadaho Nakamura1,2, Fumito Naganuma1,2, Kazuhiko Yanai1, Takeo Yoshikawa1
1

Dept Pharmacol Tohoku Univ Grad Sch Med, 2Tohoku Medical and Pharmaceutical University

Copyright © The Japanese Pharmacological Society

1-LBS-02
NCC-3902, a novel late sodium current blocker, exhibits potent
antiarrhythmic effect in isolated guinea pig pulmonary vein and canine rapid
atrial pacing model
Iyuki Namekata1, Haruhito Hiiro1, Ryosuke Odaka1, Taro Saito1, Shogo Hamaguchi1,Tadaaki Tsukamoto2, Ryutaro Ishikawa2, Yu Kawai2, Yoshimi Katayama2, Yoshiki Kondo3,Hikaru Tanaka1
1

Dept. Pharmacol., Toho Univ. Fclt. Pharmaceut. Sci, 2Pharmaceuticals Grp., Bio. Res. Lab., Nissan Chem.,
Pharmaceuticals Div., HO., Nissan Chem.

3

Copyright © The Japanese Pharmacological Society

1-LBS-03
Effects of cellular senescence on secretion of extracellular vesicles inneonatal rat cardiac fibroblasts
Yusei Fujioka, Kosuke Otani, Makoto Sugiyama, Muneyoshi Okada, Hideyuki Yamawaki
Lab.Vet. Pharmacol. & Vet. Anat., Sch. Vet. Med., Kitasato Univ.

Copyright © The Japanese Pharmacological Society

1-LBS-04
Search for novel antifibrotic agents using nonalcoholic steatohepatitis(NASH) organoid model
Kiwamu Tanabe, Tatsuya Usui, Kazuaki Sasaki
Tokyo Univ. of Agr. and Tech. Cooperative Dept. of Veterinary Med.

Copyright © The Japanese Pharmacological Society

1-LBS-05
Ramelteon enhances memory acquisition of object recognition in mice
Mikuru Kudara1, Nobuyoshi Matsumoto1,2, Yuji Ikegaya1,21

Grad Sch Pharmaceut Sci, Univ Tokyo, 2Inst AI and Beyond, Univ Tokyo

Copyright © The Japanese Pharmacological Society

2-LBS-06
SUMO1 Modification of Tau in Progressive Supranuclear Palsy
Shinsuke Matsuzaki1,2, Hironori Takamura2,3, Yoshiaki Nakayama4, Hidefumi Ito4,Taiichi Katayama2, Paul Fraser5
1

Department of Radiological Sciences, Faculty of Health Sciences, Morinomiya University of Medical Sciences,
Dept. Child Dev. & Mol. Brain Sci, Ctr. for Child Mental Dev, United Grad. Sch. of Child Dev, Osaka University,
3
Osaka Bio-Medical College, 4Department of Neurology, Wakayama Medical University,5Tanz Centre for Researchin Neurodegenerative Diseases, University of Toronto2

Copyright © The Japanese Pharmacological Society

2-LBS-07
Nalmefene, a reducing alcohol consumption drug, enhanced oxLDL
uptake in macrophages and aggravates atherosclerotic plaque formation in
apolipoprotein E knockout mice.
Mitsuhisa Koga1, Koshun Inada2, Ayano Yamada1, Chika Inatomi2, Miyu Uemura2,Chisa Teramoto2, Jiro Takata1, Atsushi Yamauchi2
1

Dept. Drug Delivery, Fac. Pharmaceut. Sci., Fukuoka Univ., 2Dept. Pharmaceut. Care & Health Sci., Fac.
Pharmaceut. Sci., Fukuoka Univ.

Copyright © The Japanese Pharmacological Society

2-LBS-08
Metabolic alterations associated with cellular senescence induced bysustained NFκB activation
Sho Tabata1, Yoshihiro Izumi2, Masatomo Takahashi2, Takeshi Bamba2, Mariko Okada1
1

IPR, Osaka Univ., 2MIB, Kyushu Univ.

Copyright © The Japanese Pharmacological Society

3-LBS-09
PDGFRβ signal inhibition in brain pericytes reverses the decreased
expression of astrocytic glutamate transporter EAAT2 in the hippocampus of
traumatic brain injury model miceKenta Sakai1, Fuyuko Takata2, Toshiro Matsui1,3, Shinya Dohgu21Res. & Dev. Ctr. for Five-Sense Devices., Kyushu Univ.,2Dept. Pharmaceut. Care & Health Sci., Fac. Pharmaceut.
Sci., Fukuoka Univ., 3Dept. of Biosci. & Biotech. Fac. of Agr., Kyushu Univ.

Copyright © The Japanese Pharmacological Society

3-LBS-10
HDL mimetics promotes mitochondrial function in mouse myoblast cells.
Tomohiro Komatsu1,2, Shihoko Nakashima3, Satomi Abe1, Takahiro Iwamoto2, Yoshinari Uehara1,3
1

Research Institute for Physical Activity, Fukuoka University, Fukuoka, Japan, 2Department of Pharmacology,Fukuoka University School of Medicine, Fukuoka, Japan, 3Faculty of Sports and Health Science, Fukuoka
University, Fukuoka, Japan

Copyright © The Japanese Pharmacological Society

3-LBS-11
Induction of metallothionein expression by Cyclosporin A
Yukihiko Tamura1, Yasuka Kusumoto2, Tsutomu Iwamoto2, Yoshihiro Waki31

Dept. Dent. Pharmacol., Tokyo Medical & Dental Univ., 2Dept. Pediatr Dent/Special Needs Dent., Tokyo Medical& Dental Univ., 3Dept. Pharmaceut. Sci., Nihon Pharmaceut. Univ.

Copyright © The Japanese Pharmacological Society