CURRICULUM VITAE
Name:

Ryo Takita, Ph.D.

Nationality:

Japanese

Present address:

School of Pharmaceutical Sciences,
University of Shizuoka
52-1 Yada, Suruga-ku, Shizuoka 422-8526, Japan
Tel: +81-54-264-5746
e-mail: takita [at] u-shizuoka-ken.ac.jp

EDUCATION
2006.3

Ph.D., Graduate School of Pharmaceutical Sciences, The University of Tokyo(supervisor: Prof. Masakatsu Shibasaki)

2001.3

B.Sc., The University of Tokyo

CAREER
2022.7-

Professor, School of Pharmaceutical Sciences,
University of Shizuoka

2018.4-2022.6

Associate Professor, Graduate School of Pharmaceutical Sciences,
The University of Tokyo

2014.2-2018.3

Deputy Team Leader, Advanced Elements Chemistry Research Team,RIKEN Center for Sustainable Resource Science

2012.4-2014.1

Lecturer, Graduate School of Pharmaceutical Sciences,
The University of Tokyo

2010.8-2012.3

Assistant Professor, Graduate School of Pharmaceutical Sciences,
The University of Tokyo

2007.4-2010.7

Assistant Professor, Institute for Chemical Research,
Kyoto University

2006.4-2007.3

Postdoctoral Fellow (JSPS Fellowships for Research Abroad),
Massachusetts Institute of Technology(working with Prof. Timothy M. Swager)

ORIGNAL PAPERS
1.

Controlled Tetradeuteration of Straight-Chain Fatty Acids: Synthesis,
Application, and Insight into the Metabolism of Oxidized Linoleic Acid
Ayako Watanabe,‡ Kotaro Hama,*‡ Kohei Watanabe, Yuko Fujiwara, Kazuaki
Yokoyama, Shigeo Murata, and Ryo Takita*(‡ co-first authors)

Angew. Chem. Int. Ed. 2022, 61, e202202779. (DOI: 10.1002/anie.202202779)<Front Cover> (DOI:10.1002/anie.202207054)(Press release from UTokyo)
2.

Synthesis of 3-Allylindoles via Annulation of N-Allyl-2-ethynylaniline
Derivatives Using a P,Olefin Type Ligand/Pd(0) Catalyst
Takashi Mino,* Toshiki Yamaoka, Kohei Watanabe,* Chihiro Masuda, Shohei
Kasano, Yasushi Yoshida, Ryo Takita, Yoshio Kasashima, and Masami
Sakamoto
J. Org. Chem. 2022, 87, 7365-7377. (DOI: 10.1021/acs.joc.2c00588)

3.

Mechanistic Details of Asymmetric Bromocyclization with BINAP Monoxide:
Identification of Chiral Proton-Bridged Bisphosphine Oxide Complex and Its
Application to Parallel Kinetic Resolution
Kenji Yamashita, Ryo Hirokawa, Mamoru Ichikawa, Tatsunari Hisanaga,
Yoshihiro Nagao, Ryo Takita, Kohei Watanabe, Yuji Kawato, and Yoshitaka
Hamashima
J. Am. Chem. Soc. 2022, 144, 3913-3924. (DOI: 10.1021/jacs.1c11816)

4.

Hydroalkylation of styrenes with benzylamines by potassium hydride
Jia Hao Pang, Bin Wang, Kohei Watanabe, Ryo Takita,* and Shunsuke Chiba*
Helv. Chim. Acta 2021, 104, e2100120. (DOI: 10.1002/hlca.202100120)

5.

Molecular basis for two stereoselective Diels-Alderases that produce decalinskeletons
Keisuke Fujiyama, Naoki Kato, Suyong Re, Kiyomi Kinugasa, Kohei
Watanabe,

Ryo Takita, Toshihiko Nogawa, Tomoya Hino, Hiroyuki Osada,

Yuji Sugita, Shunji Takahashi, and Shingo Nagano
Angew. Chem. Int. Ed. 2021, 60, 22401-22410.
(DOI: 10.1002/anie.202106186)<Inside Cover Picture>: Angew. Chem. Int. Ed. 2021, 60, issue 41. (DOI:
10.1002/anie.202109381)

6.

Hydromagnesiation of 1,3-enynes by magnesium hydride for synthesis of triand tetra-substituted allenes
Bin Wang, Yihang Li, Jia Hao Pang, Kohei Watanabe, Ryo Takita,* andShunsuke Chiba*
Angew. Chem. Int. Ed. 2021, 60, 217-221. (DOI: 10.1002/anie.202012027)

7.

Cu(I)/sucrose-catalyzed hydroxylation of arenes in water: the dual role ofsucroseKohei Watanabe,* Mio Takagi, Ayakao Watanabe, Shigeo Murata, and
Ryo Takita*
Org. Biomol. Chem. 2020, 18, 7827-7831. (DOI: 10.1039/D0OB01683G)

8.

Stereo-controlled anti-hydromagnesiation of aryl alkynes by magnesium
hydridesBin Wang, Derek Yiren Ong, Yihang Li, Jia Hao Pang, Kohei Watanabe,
Ryo Takita,* and Shunsuke Chiba*
Chem. Sci. 2020, 11, 5267-5272. (DOI: 10.1039/D0SC01773F)

9.

Zn(II) 2,9-dimethyl-1,10-phenanthroline stimulates cultured bovine aortic
endothelial cell proliferation
Takehiro Nakamura, Eiko Yoshida, Takato Hara, Tomoya Fujie, Chika
Yamamoto, Yasuyuki Fujiwara, Fumihiko Ogata, Naohito Kawasaki, Ryo
Takita, Masanobu Uchiyama, and Toshiyuki Kaji
RSC Adv. 2020, 10, 42327-42337. (DOI: 10.1039/d0ra06731h)10.

Biaryl cross-coupling enabled by photo-induced electron transfer
Hirohito Hayashi, Bin Wang, Xiangyang Wu, Shi Jie Teo, Atsushi Kaga, Kohei
Watanabe, Ryo Takita, Edwin K. L. Yeow, and Shunsuke Chiba
Adv. Synth. Catal., 2020, 362, 2223-2231. (DOI: 10.1002/adsc.201901601)

11.

Leaving Group Ability in Nucleophilic Aromatic Amination by Sodium
Hydride-Iodide Composite
Jia Hao Pang, Derek Yiren Ong, Kohei Watanabe, Ryo Takita,* and Shunsuke
Chiba*
Synthesis 2020, 52, 393-398. (DOI: 10.1055/s-0039-1690010)

12.

Mechanistic Insights on Reduction of Carboxamides by Diisobutylaluminum
Hydride and Sodium Hydride-Iodide Composite
Derek Yiren Ong, Kohei Watanabe, Ryo Takita,* and Shunsuke Chiba*
Helv. Chim. Acta 2019, 102, e1900166. (DOI: 10.1002/hlca.201900166)

13.

Organocopper Cross-coupling Reaction for C–C Bond Formation on Highly
Sterically Hindered Structures
Miku Oi, Ryo Takita,* Junichiro Kanazawa, Atsuya Muranaka, Chao Wang,
and Masanobu Uchiyama*
Chem. Sci. 2019, 10, 6107-6112. (DOI: 10.1039/c9sc00891h)(Highlighted by SYNFACTS, SYNFACTS 2019, 15, 873.)

14.

Controlled Reduction of Carboxamides to Alcohols or Amines by Zinc
HydridesDerek Yiren Ong, Zhihao Yen, Asami Yoshii, Julia Revillo Imbernon, Ryo
Takita,* and Shunsuke Chiba*
Angew. Chem. Int. Ed. 2019, 58, 4992-4997. (DOI: 10.1002/anie.201900233)

15.

Copper-catalyzed Arene Amination in Pure Aqueous Ammonia
Mio Takagi,‡ Ayakao Watanabe,‡ Shigeo Murata, and Ryo Takita* (‡ co-firstauthors)
Org. Biomol. Chem. (New Talent Themed Issue) 2019, 17, 1791-1795. (DOI:
10.1039/C8OB02708K)

16.

A Simple and Easy Method of Monitoring Doxorubicin Release from a
Liposomal Drug Formulation in the Serum Using Fluorescence Spectroscopy
Ayako Watanabe, Shuhei Murayama, Koji Karasawa, Eiichi Yamamoto,
Satoru Morikawa, Ryo Takita, Shigeo Murata, and Masaru Kato
Chem. Pharm. Bull. 2019, 67, 367-371. (DOI: 10.1248/cpb.c18-00868)(Highlighted Paper selected by Editor-in-Chief)

17.

Deprotonative Metalation of Methoxy-Substituted Arenes using Lithium
2,2,6,6-Tetramethylpiperidide: Experimental and Computational Study
Gaku Akimoto, Mai Otsuka, Ryo Takita, Masanobu Uchiyama, Madani Hedidi,
Ghenia Bentabed-Ababsa, Frédéric Lassagne, William Erb, and Florence
MonginJ. Org. Chem. 2018, 83, 13498-13506. (DOI: 10.1021/acs.joc.8b02397)

18.

Control of the Stereochemical Course of [4+2] Cycloaddition during transDecalin Formation by Fsa2-Family Enzymes
Naoki Kato, Toshihiko Nogawa, Ryo Takita, Kiyomi Kinugasa, Misae Kanai,
Masanobu Uchiyama, Hiroyuki Osada, and Shunji Takahashi
Angew. Chem. Int. Ed. 2018, 57, 9754-9758. (DOI: 10.1002/anie.201805050)(Highlighted by SYNFACTS, SYNFACTS 2018, 14,1093.)

19.

Cross-Coupling Polycondensation via C–O or C–N Bond Cleavage
Ze-Kun Yang, Ning-Xin Xu, Ryo Takita, Atsuya Muranaka, Chao Wang, andMasanobu Uchiyama
Nature Commun. 2018, 9, article number 1587. (DOI: 10.1038/s41467-01803928-z)

20.

One-pot Annulation for Biaryl-fused Monocarba-closo-dodecaborate throughAromatic B-H Bond Disconnection
Gaku Akimoto, Mai Otsuka, Kazunori Miyamoto, Atsuya Muranaka, Daisuke
Hashizume, Ryo Takita,* and Masanobu Uchiyama*
Chem. Asian J. 2018, 13, 913-917. (DOI: 10.1002/asia.201800053)(Highlighted by ChemistryViews by WIELY-VCH & ChemPubSoc Europe, onwww.chemitsryviews.org./)21.

Arylation Reactions of Monocarba-closo-Dodecaborate at the Boron Vertices
Mai Otsuka, Gaku Akimoto, Atsuya Muranaka, Ryo Takita,* and Masanobu
Uchiyama*
Heterocycles (special issue) 2018, 97, 931-945.

(DOI: 10.3987/COM-18-

S(T)72)
22.

Dearylation of Arylphosphine Oxides by a Sodium Hydride-Iodide Composite
Ciputra Tejo, Jia Hao Pang, Derek Yiren Ong, Miku Oi, Masanobu Uchiyama,
Ryo Takita,* and Shunsuke Chiba*
Chem. Commun. 2018, 54, 1782-1785. (DOI: 10.1039/c8cc00289d)

23.

“Dumbbell”- and “Clackers”-Shaped Dimeric Derivatives of Monocarbacloso-dodecaborate
Yu Kitazawa, Mamoru Watanabe, Yui Masumoto, Mai Otsuka, Kazunori
Miyamoto, Atsuya Muranaka,

Daisuke Hashizume, Ryo Takita, andMasanobu Uchiyama
Angew. Chem. Int. Ed. 2018, 57, 1501-1504. (DOI: 10.1002/anie.201710122)

24.

One-step Conversion of Levulinic Acid to Succinic Acid Using I2/t-BuOK
System: The Iodoform Reaction Revisited
Ryosuke Kawasumi, Shodai Narita, Kazunori Miyamoto, Ken-ichi Tominaga,
Ryo Takita, and Masanobu Uchiyama
Sci. Rep. 2017, 7, article number 17967. (DOI:10.1038/s41598-017-17116-4)

25.

Nucleophilic Amination of Methoxy Arenes by a Sodium Hydride/Iodide
Composite
Atsushi Kaga, Hirohito Hayashi, Hiroyuki Hakamata, Miku Oi, Masanobu
Uchiyama, Ryo Takita,* and Shunsuke Chiba*
Angew.

Chem.

Int.

Ed.

2017,

56,

11807-11811.

(DOI: 10.1002/anie.201705916)(Highlighted by SYNFACTS, SYNFACTS 2017, 13, 1248.)
26.

Catalyst-Dependent Intrinsic Ring-Walking Behavior on π-Face of Conjugated
Polymers
Koichiro Mikami, Masataka Nojima, Yui Masumoto, Yoshihide Mizukoshi,
Ryo Takita, Tsutomu Yokozawa, and Masanobu Uchiyama
Polym. Chem. 2017, 8, 1708-1713. (DOI: 10.1039/c6py01934j)

27.

“Naked” Lithium Cation: Strongly Activated Metal Cations Facilitated by
Carborane Anions
Yu Kitazawa, Ryo Takita,* Kengo Yoshida, Atsuya Muranaka, Seijiro
Matsubara,and Masanobu Uchiyama*J. Org. Chem. 2017, 82, 1931-1935. (DOI: 10.1021/acs.joc.6b02677)
28.

Catalytic Aromatic Borylation via in situ-Generated Borenium Species
Fumiya Kitani, Ryo Takita,* Tatsushi Imahori and Masanobu Uchiyama*
Heterocycles (special issue), 2017, 95, 158-166.

(DOI: 10.3987/COM-16-

S(S)43)29.

Direct Hydroxylation and Amination of Arenes via Deprotonative Cupration
Noriyuki Tezuka, Kohei Shimojo, Keiichi Hirano, Shinsuke Komagawa,
Kengo Yoshida, Chao Wang, Kazunori Miyamoto, Tatsuo Saito, Ryo Takita,
and Masanobu Uchiyama
J. Am. Chem. Soc. 2016, 138, 9166-9171. (DOI: 10.1021/jacs.6b03855)(Highlighted by SYNFACTS, SYNFACTS 2016, 12, 1071.)

30.

Conjugation between σ- and π-Aromaticity in 1-C-Arylated Monocarba-closododecaborate Anions
Mai Otsuka, Ryo Takita,* Junichiro Kanazawa, Kazunori Miyamoto, Atsuya
Muranaka, and Masanobu Uchiyama*J. Am. Chem. Soc. 2015, 137, 15082-15085. (DOI: 10.1021/jacs.5b10321)

31.

Perfluoroalkyl and -aryl Zinc Ate Complexes: Generation, Reactivity, andSynthetic Application
Xuan Wang, Keiichi Hirano, Daisuke Kurauchi, Hisano Kato, Naoyuki
Toriumi,Ryo Takita, and Masanobu Uchiyama
Chem. Eur. J. 2015, 21, 10993-10996. (DOI: 10.1002/chem.201501811)32.

Pd-catalyzed Cross-coupling Reaction of Lithiated Monocarba-closododecaborate at the Carbon Vertex
Yu Kitazawa, Mai Otsuka, Junichiro Kanazawa, Ryo Takita,* and Masanobu
Uchiyama*
Synlett 2015, 26, 2403-2407. (DOI: 10.1055/s-0034-1378833)

33.

Trans-Diborylation of Alkynes: Pseudo-Intramolecular Strategy Utilizing a
Propargylic Alcohol Unit
Yuki Nagashima, Keiichi Hirano, Ryo Takita, and Masanobu Uchiyama
J. Am. Chem. Soc. 2014, 136, 8532-8535. (DOI: 10.1021/ja5036754)(Highlighted by SYNFACTS, SYNFACTS 2014, 10, 967.)

34.

Diastereoselective deprotonative metalation of chiral ferrocene derived acetals
and esters using mixed lithium–cadmium and lithium–zinc combinations
Gandrath Dayaker, Aare Sreeshailam, D. Venkata Ramana, Floris Chevallier,
Thierry Roisnel, Shinsuke Komagawa, Ryo Takita, Masanobu Uchiyama,
Palakodety Radha Krishna, and Florence Mongin
Tetrahedron 2014, 70, 2102-2117. (DOI: 10.1016/j.tet.2014.02.010)

35.

Design, Generation, and Synthetic Application of Borylzincate: Borylation of
Aryl Halides and Borylzincation of Benzynes/Terminal Alkyne
Yuki Nagashima, Ryo Takita,* Kengo Yoshida, Keiichi Hirano, and Masanobu
Uchiyama*
J. Am. Chem. Soc. 2013, 135, 18730-18733. (DOI: 10.1021/ja409748m)(Highlighted by SYNFACTS, SYNFACTS 2014, 10, 306.)

36.

[closo-1-CB11H11-1-Ph]– as a Structural Element for Ionic Liquid Crystals
Aleksandra Jankowiak, Junichiro Kanazawa, Piotr Kaszyński, Ryo Takita, andMasanobu Uchiyama
J. Organomet. Chem. 2013, 747, 195-200.
(DOI: 10.1016/j.jorganchem.2013.05.034)

37.

Copper-Mediated C–C Cross-Coupling Reaction of Monocarba-closododecaborate Anion for the Synthesis of Functional Molecules
Junichiro Kanazawa, Ryo Takita,* Aleksandra Jankowiak, Shinya Fujii,
Hiroyuki Kagechika, Daisuke Hashizume, Koichi Shudo, Piotr Kaszyński, andMasanobu Uchiyama*
Angew. Chem. Int. Ed. 2013, 52, 8017-8021. (DOI: 10.1002/anie.201302448)(Highlighted by SYNFACTS, SYNFACTS 2013, 9, 1169.)

38.

Modified McFadyen-Stevens Reaction for a Versatile Synthesis of
Aliphatic/Aromatic Aldehydes: Design, Optimization, and Mechanistic
Investigations
Yuri Iwai, Takashi Ozaki, Ryo Takita, Masanobu Uchiyama, Jun Shimokawa,and Tohru Fukuyama
Chem. Sci. 2013, 4, 1111-1119. (DOI: 10.1039/c2sc22045h)

39.

Amidocuprates for Directed ortho Cupration: Structural Study, Mechanistic
Investigation, and Chemical Requirements
Shinsuke Komagawa, Shinya Usui, Joanna Haywood, Philip J. Harford,
Andrew E. H. Wheatley, Yotaro Matsumoto, Keiichi Hirano, Ryo Takita, andMasanobu Uchiyama
Angew.

Chem.

Int.

Ed.

2012,

51,

12081-12085.

(DOI: 10.1002/anie.201204923)
40.

Synthesis of both enantiomers of ferrocene[1,2-c]1H-quinolin-2-one bydiastereoselective deproto-zincation of sugar-derived ferrocene esters
Aare Sreeshailam, Gandrath Dayaker, D. Venkata Ramana, Floris Chevallier,
Thierry Roisnel, Shinsuke Komagawa, Ryo Takita, Masanobu Uchiyama,
Palakodety Radha Krishna, and Florence Mongin
RSC Adv. 2012, 2, 7030-7032. (DOI: 10.1039/c2ra21045b)

41.

Aryl Ether as Negishi Coupling Partner: An Approach for Constructing C-C
Bond under Mild Conditions
Chao Wang, Takashi Ozaki, Ryo Takita, and Masanobu Uchiyama
Chem. Eur. J. 2012, 18, 3482-3485. (DOI: 10.1002/chem.201103784)(Highlighted by SYNFACTS, SYNFACTS 2012, 8, 655; Selected as “Synfact ofthe month”)

42.

Direct Arylationof

Heteroarenes

Catalyzedbya Palladium–1,10-

Phenanthroline Complex
Ryo Takita,* Daichi Fujita, and Fumiyuki Ozawa*
Synlett 2011, 959-963. (DOI: 10.1055/s-0030-1259727)
43.

Palladium-Catalyzed Dehydrohalogenative Polycondensation of 2-Bromo-3hexylthiophene:An

EfficientApproachtoHead-to-TailPoly(3-

hexylthiophene)
Qifeng Wang, Ryo Takita,* Yuuta Kikuzaki, and Fumiyuki Ozawa*J. Am. Chem. Soc. 2010, 132, 11420-11421. (DOI: 10.1021/ja105767z)(Highlighted by Angewandte Highlights, Angew. Chem. Int. Ed. 2012, 51,
3520-3523.)
44.

Synthesis and structures of platinum diphenylacetylene and dithiolate
complexes bearing diphosphinidenecyclobutene ligands (DPCB-Y)
Yumiko Nakajima, Mitsuharu Nakatani, Kyohei Hayashi, Yu Shiraishi, Ryo
Takita, Masaaki Okazaki, and Fumiyuki Ozawa
New J. Chem. 2010, 34, 1713-1722. (DOI: 10.1039/c0nj00118)

45.

The Effects of Primary Structures on Photo-induced Insolubilization of All-cis
Poly(p-phenylenevinylene)s in Thin Films
Yuichiro Mutoh, Yasutaka Yamamoto, Masayuki Wakioka, Ryo Takita, Jun-ichi
Nakamura, Toshiya Iida, and Fumiyuki Ozawa
Bull. Chem. Soc. Jpn. 2009, 82, 1533-1537. (DOI: 10.1246/bcsj.82.1533)

46.

A Highly Selective Catalytic System for the Cross-Coupling of (E)-Styryl
Bromide with Benzeneboronic Acid: Application to the Synthesis of All-transPoly(arylenevinylene)s
Masayuki Wakioka, Yuichiro Mutoh, Ryo Takita, and Fumiyuki Ozawa
Bull. Chem. Soc. Jpn. 2009, 82, 1292-1298. (DOI: 10.1246/bcsj.82.1292)(Highlighted as “Selected Paper”)

47.

Synthesis and Ligand Properties of 1-Phosphaethenyl-2-phosphanylferrocenes
Ryo Takita, Yuko Takada, Rader S. Jensen, Masaaki Okazaki, and Fumiyuki
Ozawa
Organometallics 2008, 27, 6279-6285. (DOI: 10.1021/om8008316)

48.

π-Dimer Formation in an Oligothiophene Tweezer Molecule
Ryo Takita, Changsik Song, and Timothy M. Swager
Org. Lett. 2008, 10, 5003-5005. (DOI: 10.1021/ol8020995)

49.

CATALYTICENANTIOSELECTIVE

ADDITIONOFTERMINAL

ALKYNES TO ALDEHYDES: PREPARATION OF (S)-(–)-1,3-DIPHENYL2-PROPYN-1-OL AND (S)-(–)-4-METHYL-1-PHENYL-2-PENTYN-1,4DIOL
Ryo Takita, Shinji Harada, Takashi Ohshima, Shigeki Matsunaga, andMasakatsu Shibasaki
Org. Synth. 2008, 85, 118-130. (DOI: 10.15227/orgsyn.085.0118)
50.

Ligand Accelerated Indium(III)-Catalyzed Asymmetric Alkynylation of
Aldehydes with 2-Methyl-3-butyn-2-ol as an Ethyne Equivalent Donor
Shinji Harada, Ryo Takita, Takashi Ohshima, Shigeki Matsunaga, andMasakatsu Shibasaki
Chem. Commun. 2007, 948-950. (DOI: 10.1039/b614958h)

51.

Asymmetric Alkynylation of Aldehydes Catalyzed by an In(III)/BINOL
ComplexRyo Takita, Kenichiro Yakura, Takashi Ohshima, and Masakatsu Shibasaki
J. Am. Chem. Soc. 2005, 127, 13760-13761. (DOI: 10.1021/ja053946n)(Highlighted by SYNFACTS, SYNFACTS 2006, 1, 41.)

52.

A New Entry in Catalytic Alkynylation of Aldehydes and Ketones: Dual
Activation of Soft Nucleophiles and Hard Electrophiles by an Indium(III)Catalyst
Ryo Takita, Yuhei Fukuta, Riichiro Tsuji, Takashi Ohshima, and Masakatsu
Shibasaki
Org. Lett. 2005, 7, 1363-1366. (DOI: 10.1021/ol050069h)(Highlighted in Editor’s Choice of Science, Science 2005, 308, 19.)

53.

Enantioselective total synthesis of (–)-strychnine: development of a highly
practical catalytic asymmetric carbon-carbon bond formation and domino
cyclization
Takashi Ohshima, Youjun Xu, Ryo Takita, and Masakatsu Shibasaki
Tetrahedron 2004, 60, 9569-9588. (DOI: 10.1016/j.tet.2004.06.141)

54.

Catalytic Asymmetric Michael Reaction of β-Keto Esters: Effects of the Linker
Heteroatom in Linked-BINOL
Keisuke Majima, Ryo Takita, Akihiro Okada, Takashi Ohshima, and Masakatsu
Shibasaki
J. Am. Chem. Soc. 2003, 125, 15837-15845. (DOI: 10.1021/ja037635t)

55.

Enantioselective Total Synthesis of (–)-Strychnine Using the Catalytic
Asymmetric Michael Reaction and Tandem Cyclization
Takashi Ohshima, Youjun Xu, Ryo Takita, Satoshi Shimizu, Dafang Zhong, andMasakatsu Shibasaki
J. Am. Chem. Soc. 2002, 124, 14546-14547. (DOI: 10.1021/ja028457r)

56.

Highly enantioselective catalytic Michael reaction of α-substituted malonates
using La-linked-BINOL complex in the presence of HFIP (1,1,1,3,3,3hexafluoroisopropanol)
Ryo Takita, Takashi Ohshima, and Masakatsu Shibasaki
Tetrahedron Lett. 2002, 43, 4661-4665. (DOI: 10.1016/S0040-4039(02)00882-1)

REVIEWS & PERSPECTIVES
1.

Generation of organo-alkaline earth metal complexes from non-polar
unsaturated molecules and their synthetic applications
Kohei Watanabe‡, Jia Hao Pang‡, Ryo Takita,* and Shunsuke Chiba*(‡ co-first authors)
Chem. Sci. 2022, 13, 27-38. (perspective) (DOI: 10.1039/D1SC05724C)

2.

New avenues in the directed deprotometallation of aromatics: recent advancesin directed cupration
Philip J. Harford, Andrew J. Peel, Floris Chevallier, Ryo Takita, Florence
Mongin, Masanobu Uchiyama, and Andrew E. H. WheatleyDalton Trans. 2014, 43, 14181-14203. (perspective)(DOI: 10.1039/c4dt01130a)

BOOKS
1.

Deprotonative Metalation Using Alkali Metal-Non Alkali Metal Combination
Floris Chevallier, Florence Mongin, Ryo Takita, and Masanobu Uchiyama
Arene Chemistry: Reaction Mechanisms and Methods for Aromatic
Compounds (BOOK), Jacques Mortier (Ed.), WILEY, 2015. 777-812. (bookchapter)

AWARDS
2018

Thieme Chemistry Journal Award 20182017

Chemist Award BCA (Banyu Chemist Award) 20172015

Asian Core Program Lectureship Award (Singapore)

2015

The Pharmaceutical Society of Japan Award for Young Scientists

2015

RIKEN Research Insentive Award