NEURO2019

SymposiumSymposium 1S01m

Day 1 - July 25
9:00-11:00

Room 1 (4F International Conference Room)

The molecular/cellular mechanisms and the roles of REM sleep in brain
functions

1S01m-1（9:00）

Hiroki Ueda ‌University of Tokyo/RIKEN
Yu Hayashi ‌University of Tsukuba

Identification of neurons regulating REM sleep and insights to the mechanisms of REM sleep behavior
disorderYu Hayashi
International Institute for Integrative Sleep Medicine (WPI-IIIS), Univ of Tsukuba, Tsukuba, Japan

1S01m-2（9:20）

Systems Biology of Mammalian Sleep/Wake Cycles Toward Molecular definition of NREM and REM
sleepsHiroki R Ueda1,2,3
WPI-IRCN, UTIAS, The University of Tokyo, Japan
Systems Pharmacology, Graduate School of Medicine, University of Tokyo, Japan1
2

1S01m-3（9:40）RIKEN (BDR), Japan3

Sleep stage dynamics in dragon hippocampus
Hiroaki Norimoto
Max Planck Institute for Brain Research

1S01m-4（10:00）Experience and sleep-dependent synapse remodeling
Guang Yang
Columbia Univ

1S01m-5（10:20）

Reactivation of memory engram during REM/nonREM sleep
Kaoru Inokuchi
Univ. of Toyama, Toyama, Japan

1S01m-6（10:40）Decoding dream contetns from human brain activity in REM and non-REM sleep
Yukiyasu Kamitani
Kyoto Univ. Grad. Sch. of Informatics

Symposium 1S02m

9:00-11:00

Roles of epigenetics and inflammation in mental illness
Chairpersons：Room 2 (2F Main HallA)

Tomoyuki Furuyashiki ‌Kobe University Graduate School of Medicine
Zhen Yan ‌School of Medicine and Biomedical Sciences, State University of New York at Buffalo, USA

Opening remark Tomoyuki Furuyashiki
Div Pharmacol, Grad Sch Med, Kobe Univ, Kobe, Japan（9:00）
1S02m-1（9:03）

Epigenetic Rescue of Autism-like Social Deficits in Shank3-Deficient Mice
Zhen Yan
State Univ of New York at Buffalo

1S02m-2（9:31）

Genetic and epigenetic variations of neuronal cells and their implications for psychiatric disorders
Kazuya Iwamoto1，Miki Bundo1,2，Tadafumi Kato3
Grad Sch Med Sci, Dep Mol Brain Sci, Kumamoto University

1

1S02m-3（9:59）PRESTO JST

2

RIKENCBS

3

Stress-induced local inflammatory responses in the brain for emotional changes: possible relevanceof epigenetic regulation
Tomoyuki Furuyashiki
Div Pharmacol, Grad Sch Med, Kobe Univ, Kobe, Japan103

Symposium
July 25

Chairpersons：1S02m-4（10:27）Microglia-focused neuropsychiatric translational research using human bloods; dynamic cellular
analysis with induced microglia-like (iMG) cells and various plasma analysis
Takahiro A. Kato，Masahiro Ohgidani，Shigenobu Kanba
Dept Neuropsychiatry, Grad Sch Med Sci, Kyushu Univ, Fukuoka, Japan

Concluding remark Zhen Yan
State Univ of New York at Buffalo（10:55）
Symposium 1S03m

9:00-11:00

Room 3 (2F Main HallB)

Emerging roles of neuropeptides in emotional valence representation forsurvivial
Chairpersons：

Yukari Takahashi ‌Dept Neurosci, Jikei Univ Sch Med
Mumeko Tsuda ‌Uniformed Services University of the Health Sciences at Walter Reed Naval BaseIntroduction Yukari Takahashi
Dept Neurosci, Jikei Univ Sch Med（9:00）
1S03m-1（9:03）

Oxytocin modulates emotional tears
Takefumi Kikusui1，Kaori Murata1，Toshihiro Imada2，Jin Kai2，Kazutaka Mogi1，Miho Nagasawa1，
Shigeru Nakamura2，Kazuo Tsubota2
School of Veterinary Medicine, Azabu University

1

1S03m-2（9:30）

Department of Ophthalmology Keio University School of Medicine

2

Male aggression gated by TIP39 signaling in the medial amygdala
Mumeko C Tsuda1,2，Brian Coleman2，Maria Perica2，Jonathan Kuo2，Ted B Usdin2
Uniformed Services University, Bethesda, Maryland, USA
Section on Fundamental Neuroscience, National Institute of Mental Health, Bethesda, Maryland, USA

12

1S03m-3（9:57）

Synaptic regulation by CGRP in the nociceptive amygdala
Yukari Takahashi，Yuya Okutsu，Kei Shinohara，Mariko Sugimoto，Yae K Sugimura，Fusao Kato
Dept. Neurosci, Jikei Univ Sch Med

1S03m-4（10:24）

Neuropeptidergic regulation of negative valence and sensory response
Masato Tsuji1，Kazuo Emoto1,2Dept. of Biological Sciences, the University of Tokyo, Tokyo, Japan
Neurointelligence International Research Institute (WPI-IRCN), The University of Tokyo, Tokyo, Japan1
2

Discussion（10:51）
Symposium 1S04m

Brain diversity induced by glial heterogeneity

9:00-11:00

Room 4 (3F 301)

Sponsored by IBRO-APRC Lecturer Exchange Program
Chairpersons：

Schuichi Koizumi ‌Dept Neuropharmacol, Interdisciplinary Grad Sch Med, Univ Yamanashi
Rieko Muramatsu ‌Department of Molecular Pharmacology, National Institute of Neuroscience, National
Center of Neurology and Psychiatry

1S04m-1（9:00）

Glial heterogeneity for the neuronal network regeneration
Rieko Muramatsu
Dept Mol Pharmacol, Nat Inst Neurosci, NCNP

1S04m-2（9:30）

Heterogeneity of astrocytes as observed in glycogen distribution
Hajime Hirase1,2，Yuki Oe1
Lab. for Neuron-Glia Circuitry, RIKEN CBS

1

104

CTN, Univ of Copenhagen, Copenhagen, Denmark2

NEURO2019

1S04m-3（10:00）Astrocytic heterogeneity in modulating sensory signal processing
Sun Kwang Kim1，Sang Jeong Kim2，Schuichi Koizumi3，Junichi Nabekura4
Kyung Hee University College of Korean Medicine 2Seoul National University School of Medicine
Yamanashi University Faculty of Medicine 4National Institute for Physiological Sciences

1
3

1S04m-4（10:30）

Heterogeneity of astrocytes in synapse remodelingSymposium 1S05m

9:00-11:00

Matching matters: Roles of trans-synaptic protein interactions

Room 5 (3F 302)

Sponsored by IBRO-APRC Lecturer Exchange Program
Chairpersons：

1S05m-1（9:00）

Kensuke Futai ‌University of Massachusetts Medical School
Ji Won Um ‌Daegu Gyeongbuk Institute of Science and Technology

Neuroligin-mediated input-specific homeostatic plasticity
Kensuke Futai1，Motokazu Uchigashima1,2，Takuya Watanabe1，Amy Cheung1，Manabu Abe3，
Kenji Sakimura3，Masahiko Watanabe2
Dept. Neurobiology, Univ. Massachusetts Medical School, Worcester, U.S.A.
Dept. of Anatomy, Hokkaido Univ., Grad. Sch. of Medicine, Sapporo, Japan
3
Dept. Cell Neurobiol., Brain Res. Inst., Niigata Univ., Niigata, Japan1
2

1S05m-2（9:24）The C1q complement family proteins and glutamate receptors; bridge over the synaptic cleft
Keiko Matsuda
Dept. of Physiology, Keio Univ. Sch. of Medicine, Tokyo, Japan

1S05m-3（9:48）

Functional roles of synapse organizers in the cerebellum
Takeshi Uemura1,2,3
Div. of Gene Res., Res. Cent. for Supports to Advanced Science, Shinshu Univ., Nagano, JapanIBS-ICCER, Shinshu Univ., Nagano, Japan 3CREST, JST, Saitama, Japan1
2

1S05m-4（10:12）Distinct roles of canonical and non-canonical synaptogenic signaling of neuroligin 3
Tomoyuki Yoshida1，Ayako Imai-Tabata1，Atsushi Yamagata2，Hironori Izumi1，Tomoko Shiroshima2，
Juhyon Kim3，Masaki Fukata4，Keizo Takao5，Hisashi Mori1，Shuya Fukai2
Dept Mol Neurosci, Grad Sch of Med and Pharma Sci, Univ of Toyama, Toyama 2Inst Quant Biosci, Univ of Tokyo, Japan
Dept Bio Info Engineering, Univ of Toyama, Toyama 4Div Membrane Physiol, Dept Mol Cell Physiol, NIPS, Aichi, Japan
5
Life Sci Res Ctr, Univ of Toyama, Toyama
13

1S05m-5（10:36）

Postsynaptic Calsyntenin-3 Requires Direct Interactions with Presynaptic Neurexins to Orchestrate
Excitatory Synapse Development in the Hippocampus
Ji Won Um1，Hyenho Kim1，Dongwook Kim1，Hee-yoon Lee2，Hyeyeon Kang1，Dongseok Park1，
Soo-Jeong Kim1，Keiko Matsuda3，Fredrik H Sterky4，Michisuke Yuzaki3，Jin Young Kim5，
Se-Young Choi2，Jaewon Ko1
DGIST, Daegu, South Korea 2Seoul National University, Seoul, Korea 3Keio University, Tokyo, Japan
University of Gothenburg, Gothenburg, Sweden 5Korea Basic Science Institute, Cheongju, Korea

14

Symposium 1S06m

9:00-11:00

Room 6 (2F 201A)

Impact of new advances in the DAMPs/alarmins and neuroinflammation
researches on diverse neuronal diseases
Chairpersons：Atsufumi Kawabata ‌Laboratory of Pharmacology and Pathophysiology, Faculty of Pharmacy, Kindai
Hitoshi Okazawa

University‌Department of Neuropathology, Medical Research Institute, Tokyo Medical and

Dental University

Introduction Atsufumi Kawabata
Lab Pharmacol Pathophysiol, Fac Pharm, Kindai Univ, Higashi-Osaka, Japan（9:00）

105

Symposium
July 25

Schuichi Koizumi
Dept Neuropharmacol, Grad Sch Med, Univ Yamanashi

1S06m-1（9:03）

Sex and cell dependent roles of disulfide HMGB1 in spinal and peripheral pain mechanisms
Camilla Svensson
Dept. Physiology and Pharmacology, Center for Molecular Medicine, Karolinska Institute, Stockholm, Sweden

1S06m-2（9:28）

Role of peripheral HMGB1 and thrombomodulin/thrombin in neuropathic pain
Atsufumi Kawabata
Lab Pharmacol Pathophysiol, Fac Pharm, Kindai Univ, Higashi-Osaka, Japan

1S06m-3（9:50）

Anti-HMGB1 antibody-induced preservation of lesion site and its therapeutic application for spinal
cord injury
Kinichi Nakashima
Dep Stem Cell Biol Med, Grad Sch Med Sci, Fukuoka, Japan

1S06m-4（10:12）

Cerebral ischemia-induced non-classical/non-vesicular release of Alarmins and neuroprotection
Hiroshi Ueda
Dept. of Pharmacol Ther Innov, Nagasaki Univ. Grad. Sch. of Biomed Sci

1S06m-5（10:34）

Dynamics of HMGB1 in epileptic status and beneficial effects of systemic injection of anti-HMGB1mAb
Masahiro Nishibori1，Li Fu1，Hideo Kohka Takahashi2，Shuji Mori3
Dept of Pharmacol. Okayama Univ.

1

Dept of Pharmacol. Kindai Univ

2

Symposium 1S02a

Dept of Pharmacol. Shujitsu Univ

3

14:40-16:40

Room 2 (2F Main HallA)

Neuroscience study based on brain bank networking in Japan for the cure of
intractable neuropsychiatric disorders
Chairpersons：Shigeo Murayama ‌Tokyo Metropolitan Geriatric Hospital and Institute of Gerontology
Haruhisa Inoue ‌Center for iPS Cell Research and Application (CiRA), Kyoto University

Introducation: All Japan Brain Bank Network（14:40）
Shigeo Murayama
Tokyo Metropolitan Geriatric Hospital and Institute of Gerontology

1S02a-1（15:00）Research and development of neurodegenerative diseases based on the all Japan Brain Bank
Network
Hitoshi Okazawa
Center for Brain Integration Research, Tokyo Medical and Dental Univ.

1S02a-2（15:30）

TDP-43 and DISC1 Co-Aggregation Disrupts Dendritic Local Translation and Mental Function in FTLD
Ryo Endo1，Noriko Takashima1，Yoko Nekooki-Machida1，Yusuke Komi1，Kelvin Kai-Wan Hui1，
Masaki Takao2,3，Hiroyasu Akatsu5,6，Shigeo Murayama2，Akira Sawa4，Motomasa Tanaka1Lab. for Protein Conformation Diseases, RIKEN CBS, Saitama, Japan
Dept. of Neuropathology, Tokyo Metropolitan Geriatric Hospital & Inst. of Gerontology, Tokyo Japan
3
Dept. of Neurology, Saitama Medical Univ. 4Dept. of Psychiatry, Johns Hopkins Univ. Sch. of Medicine, Baltimore, USA
5
Choju Medical Inst. Fukushimura Hospital, Aichi, Japan
6
Dept. of Medicine for Aging in Place and Community-Based Medical Nagoya City Univ. Graduate Sch. of Medical Sciences,
Nagoya, Aichi, Japan1
2

1S02a-3（16:00）From rare to common neurological diseases using iPSCs
Haruhisa Inoue1,2,3
Center for iPS Cell Research and Application, Kyoto University, Kyoto, JapanRIKEN BioResource Research Center, Kyoto, Japan 3RIKEN Center for Advanced Intelligence Project, Kyoto, Japan1
2

How to apply to BB?
（16:30）
Shigeo Murayama
Tokyo Metropolitan Geriatric Hospital and Institute of Gerontology

106

NEURO2019

Symposium 1S03a

14:40-16:40

Room 3 (2F Main HallB)

Molecular and circuit mechanisms in physiological and pathological decisionmaking behavior
Chairpersons：

A role for nucleus accumbens D1-/D2-neuron pathways in controlling learning impaired in psychiatricdisorders
Tom Macpherson，Takatoshi Hikida
Osaka University Institute for Protein Research

1S03a-2（15:10）

Mesostriatal gating of cue-triggered motivation
Benjamin Saunders
University of Minnesota

1S03a-3（15:40）

Manipulating GABAA receptors: Cocaine potentiation of conditioned responding
Sarah L King1，Marsha M Sindarto1，Jonathan Robertson1，Tom Macpherson1,2，Dai N Stephens1
School of Psychology, University of Sussex, Brighton, BN1 9QG, United Kingdom
Laboratory for Advanced Brain Functions, Institute for Protein Research, Osaka University, Japan1
2

1S03a-4（16:10）Physiological centers of decision-making in addiction: the insular cortex and striatum
Hiroyuki Mizoguchi1，Kiyofumi Yamada2
Res. Ctr. Next-Generation Drug Dev., Res. Inst. Environmental Med., Nagoya Univ.
Dep. Neuropsychopharmacol. Hosp. Pharm., Nagoya Univ. Grad. Sch. Med.

1
2

Symposium 1S04a

14:40-16:40

Room 4 (3F 301)

Understanding the homeostatic maintenance mechanisms and logistics ofcellular community in the brain "Brain Infrastructure"
Chairpersons：Taisuke Tomita ‌Laboratory of Neuropathology and Neuroscience, Graduate School of Pharmaceutical
Sciences, The University of Tokyo

Takashi Saito ‌Laboratory for Proteolytic Neuroscience, RIKEN Center for Brain Science
1S04a-1（14:40）

Neuroimmune system associated with brain development and degeneration
Shogo Tanabe
Dept. Mol Pharmacol, National Inst. of Neurosci, NCNP, Tokyo, Japan

1S04a-2（15:00）Complementarity between microglia and astrocytes in phagocytosis
Hiroyuki Konishi1，Katsuaki Sato2，Hiroshi Kiyama1
Dept Funct Anat Neurosci, Nagoya Univ Grad Sch Med, Nagoya, JapanDiv Immunol, Dept Infecti Dis, Facult Med, Univ of Miyazaki

1
2

1S04a-3（15:20）

Neuron-glia interaction in synapse elimination
Ryuta Koyama
Lab Chem Pharmacol, Grad Sch Pharm Sci, Univ of Tokyo, Tokyo

1S04a-4（15:40）

Molecular mechanisms of microglial recognition and response to amyloid β
Sho Takatori1，Akihiro Iguchi1，Shingo Kimura1，Junko Sasaki2，Takehiko Sasaki2，Toshiyuki Takai3，
Takashi Saito4，Takaomi C Saido4，Taisuke Tomita1
Lab Neuropathol Neurosci, Grad Sch Pharm Sci, Univ Tokyo, Tokyo, Japan
Dept Pathophysiol, Med Res Inst, Tokyo Med and Dent Univ, Tokyo
3
Dept Experimental Immunol, IDAC, Univ of Tohoku, Miyagi 4Lab Proteolytic Neurosci, RIKEN CBS
1
2

1S04a-5（16:00）Brain Environment Protected by Glutathione and Alzheimer's disease
Shoko Hashimoto，Yukio Matsuba，Naoko Kamano，Takashi Saito，Takaomi C Saido
Lab. for Proteolytic Neuroscience, RIKEN Center for Braiin Science

1S04a-6（16:20）In vivo multiscale imaging of glymphatic clearance of tau and alpha-synuclein from the brain
Hiroyuki Takuwa
National Institutes for Quantum and Radiological Science

107

Symposium
July 25

1S03a-1（14:40）

Takatoshi Hikida ‌Osaka University Institute for Protein Research
Sarah King ‌University of Sussex

Symposium 1S05a

14:40-16:40

Information Processing in Offline Brain
Chairpersons：

1S05a-1（14:40）

Hiroaki Norimoto ‌Max Planck Institute for brain research
Shoi Shi ‌Graduate School of Medicine, University of Tokyo

Sleep phenotype of cortical layer 5 silenced mouse
Tomoko Yamagata1，Lukas B Krone1,2，Anna Hoerder-Suabedissen2，Zoltán Molnár2，
Vladyslav V Vyazovskiy1,2
SCNi, NDCN, Univ Oxford, Oxford, UK

1

1S05a-2（15:00）

Room 5 (3F 302)

DPAG, Univ Oxford, Oxford, UK

2

Control mechanism by spiking patterns for transmission of circadian clock and homeostasis during
sleep in Drosophila
Masashi Tabuchi1，Joseph D Monaco2，Kechen Zhang2，Mark N Wu1
Dept Neurology, Johns Hopkins Medicine, Baltimore, USA

1

1S05a-3（15:20）

Dept Biomed Eng, Johns Hopkins Medicine, Baltimore, USA

2

Daily torpor in mice as a model of active hypometabolism in mammals
Genshiro A. Sunagawa
Laboratory for Retinal Regeneration, RIKEN Center for Biosystems Dynamics Research

1S05a-4（15:40）

The role of sleep hippocampal ripples for memory consolidation
Gabrielle Girardeau
Institut du Fer-a-Moulin, Inserm, Sorbonne Universite

1S05a-5（16:00）Cuttlefish behavior at cellular resolution reveals spontaneous neural activity
Sam Reiter
Max Planck Institute for Brain Research

1S05a-6（16:20）Understanding the role of Ca2+-dependent hyperpolarization pathway in sleep homeostasis
Shoi Shi1,2,3，Hiroki R. Ueda1,2,3
Department of Systems Pharmacology Graduate School of Medicine, The University of Tokyo, Tokyo, Japan
Laboratory for Synthetic Biology, RIKEN Center for Biosystems Dynamics Research, Osaka, Japan
3
International Research Center for Neurointelligence, The University of Tokyo Institutes for Advanced Study, The University ofTokyo, Tokyo, Japan1
2

Symposium 1S06a

14:40-16:40

Room 6 (2F 201A)“Towards integration of neuroscience and machine intelligence"
Chairpersons：

1S06a-1（14:40）Okito Yamashita ‌Center for advanced intelligence project
Yoshinobu Kawahara ‌The Institute of Scientific and Industrial Research, Osaka University

Impact of machine learning on human imaging research
Okito Yamashita1,2
RIKEN, Advanced Intelligence Project, Kyoto, Japan1

1S06a-2（14:50）

ATR, Neural Information Analysis Laboratories, Kyoto, Japan

2

Classification from weak supervision
Takashi Ishida
Dept. of Complexity Sci and Eng, Grad Sch of Frontier Sci, Univ of Tokyo, Japan

1S06a-3（15:12）Biologically Inspired Representation Learning for Deep Neural Networks
Takashi Shinozaki1,2
NICT

1

1S06a-4（15:34）

Osaka Univ.

2

On the role of chaos in reservoir computing
Kohei Nakajima
Grad. Sch. of Information Science and Technology, The Univ of Tokyo, Tokyo

1S06a-5（15:56）Topological complexity in the brain: Fragility, volatility, and a hierarchy of timescales
Leonardo Gollo
Systems Neuroscience Group, QIMR Berghofer Medical Research Institute, Brisbane, Australia

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NEURO2019

1S06a-6（16:18）

Data-driven Analysis of Nonlinear Dynamical Systems Based on Operator-theoretic Methods
Yoshinobu Kawahara1,2
Institute of Mathematics for Industry, Kyushu University, Fukuoka, Japan
Center for Advanced Intelligence Project, RIKEN, Tokyo, Japan1
2

Symposium 1S07a

*in Japanese
Chairpersons：Room 7 (2F 201B)

Symposium on Industry-Academia Collaboration

Manabu Honda ‌Japan Neuroscience Society Industry-Academia Partnership Committee

Manabu Honda1，Hisamichi Okamura2，Eisuke Nakazawa3，Koji Morikawa4，Junichi Ushiba5，
Runa Koike6
Japan Neuroscience Society Industry-Academia Partnership Committee 2Cyber Law Japan Eichi Law Offices
Graduate School of Medicine and Faculty of Medicine, The University of Tokyo
4
Panasonic Technology Innovation Division 5Faculty of Science and Technology, Keio University
6
NTT DATA INSTITUTE OF MANAGEMENT CONSULTING
1
3

Symposium 1S02e

16:50-18:50

Room 2 (2F Main HallA)

Simple is Best. Study of neurological disorders and regeneration using
invertebrate models
Chairpersons：

1S02e-1（16:50）Atsushi Sugie ‌Center for Transdisciplinary Research, Niigata University
Shinsuke Niwa ‌Tohoku University, Frontier Research Institute for Interdisciplinary Sciences

Disease-associated mutations in human KIF1A overactivate motility of KIF1A and anterograde axonaltransport of synaptic vesicle precursors
Shinsuke Niwa
FRIS, Tohoku Univ., Miyagi, Japan

1S02e-2（17:10）C. elegans Tensin regulates axon regeneration via Met-like signaling
Naoki Hisamoto，Kazuma Asai，Tatsuhiro Shimizu，Yoshiki Sakai，Strahil Iv Pastuhov，Hiroshi Hanafusa，Kunihiro Matsumoto
Dept Biol Sci, Grad Sch Sci, Nagoya Univ, Nagoya Japan

1S02e-3（17:30）Efficient research on neurodegenerative diseases using Drosophila models
Yoshitaka Nagai
Dept Neurotherapeutics, Osaka Univ Grad Sch of Med, Japan

1S02e-4（17:50）Proteostasis in aging and neurodegenerative diseases
Mari Suzuki
Diabetic Neuropathy Proj, Tokyo Met Inst Med Sci, Tokyo, Japan

1S02e-5（18:10）

Visualization of organelles and ultrastructures in the fly brain using three-dimensional electron
microscopy
Kazunori Shinomiya，Patricia K Rivlin，Stephen M PlazaHHMI Janelia Research Campus, Ashburn, VA, USA

1S02e-6（18:30）

Elucidation of neurodegenerative process with impairment of intercellular communication using
Drosophila model
Atsushi Sugie1，Melisande Richard2，Yohei Nitta1，Gaia Tavosanis2，Takashi Suzuki3
Transdisc Res Prog, Niigata Univ. Niigata, Japan 2German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany
School of Life Science and Technology, Tokyo Institute of Technology, Yokohama, Japan.

1
3

109

Symposium
July 25ELSI for Social Implementation of Neurotechnology

14:40-16:40

Symposium 1S03e

16:50-18:50

Room 3 (2F Main HallB)

Neuronal Substrates of Episodic Memory ~ from physiology to circuits
Chairpersons：Kazumasa Tanaka ‌RIKEN Center for Brain Science
Takashi Kitamura ‌University of Texas, Southwestern, Medical Center

Introduction Kazumasa Z Tanaka
Lab. for Circuit and Behavioral Physiol., RIKEN CBS（16:50）
1S03e-1（16:55）

Cortical Sensory Modulation of Hippocampal Activity and Spatial Representation
Jayeeta Basu，Olesia Bilash，Roland Zemla
New York University Neuroscience Institute, New York, USA

1S03e-2（17:13）

Dynamics of Hippocampal - Entorhinal Memory System in Mice
Jun Yamamoto
Dept Psychiatry Neurosci Div, Univ Texas Southwestern Medical Ctr, Dallas, Texas, USA

1S03e-3（17:31）

Dentate granule cells recruit feedforward inhibition to govern engram maintenance and remotememory generalization
Nannan Guo1,2，Marta E Soden3，Charlotte Herber1,2，Michale Kim1,2，Antoine Besnard1,2，Paoyan Lin1,2，
Constance L Cepko4，Larry S Zweifel3，Amar Sahay1,2,5
Harvard Medical School, Boston 2Center for Regenerative Medicine, Massachusetts General Hospital, Boston
Department of Pharmacology, Department of Psychiatry and Behavioral Sciences, University of Washington, Seattle
4
Howard Hughes Medical Institute, Department of Genetics, Harvard Medical School, Boston
5
BROAD Institute of Harvard and MIT, Cambridge
13

1S03e-4（17:49）Heterogeneous memory traces in the hippocampus
Kazumasa Z Tanaka1，Hongshen He1,2，Anupratap Tomar1，Kazue Niisato1，Arthur J.Y. Huang1，
Thomas McHugh1,2
Lab. for Circuit and Behavioral Physiol., RIKEN CBS

1

1S03e-5（18:07）

Dept. of Life Sci, Univ of Tokyo, Tokyo

2

Emergence of memory engrams in the rodent hippocampus
Marlene Bartos
University of Freiburg

1S03e-6（18:25）

Hippocampal circuit mechanisms for self-recognition
Takashi Kitamura，Jun Yokose
University of Texas Southwestern Medical Center

Discussion（18:43）
Symposium 1S04e

16:50-18:50

From sensory systems to goal-directed social behaviors
Chairpersons：Room 4 (3F 301)

Saori Yokoi ‌Faculty of Pharmaceutical Sciences, Hokkaido University
Azusa Kamikouchi ‌Graduate School of Science, Nagoya University

Introduction Azusa Kamikouchi
Graduate School of Science, Nagoya University（16:50）
1S04e-1（16:55）

Evolution of neural circuit for chemical communication in Drosophila
ＹｕｋｉIshikawa，Naoki Maeda，Azusa Kamikouchi
Grad. Sch. of Science, Nagoya Univ., Nagoya

1S04e-2（17:15）

Analysis of molecular/neural basis underlying decision making according to social familiarity in small
fish, medaka
Saori Yokoi
Dept. of Pharmacology, Grad. Sch. of Pharmaceutical Sciences, Hokkaido Univ.

110

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1S04e-3（17:35）

Neural circuits underlying experience-dependent behavioral changes
Hiroshi Nomura
Dept Pharmacol, Grad Sch Pharm Sci, Hokkaido Univ, Sapporo, Japan

1S04e-4（17:55）

Neural representation of sexual behavior in hypothalamus
Tomomi Karigo1，Bin Yang1，Ann Kennedy1，David J Anderson1,2
Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, USA
Howard Hughes Medical Institute, California Institute of Technology, Pasadena, USA1

Symposium
July 25

2

1S04e-5（18:15）Investigation of brain mechanisms for primate parental behavior
Kazutaka Shinozuka1，Saori Nashimoto Yano1，Chihiro Yoshihara1，Anna Truzzi2，Gianluca Esposito2，
Kenichi Tokita3，Sayaka Shindo1，Dai Watanabe4，Ryosuke Matsui4，Atsuko Saito5，Kumi Kuroda1
Lab. for Affiliative Social Behavior, RIKEN CBS 2Dept Psychol and Cognitive Sci, Univ of Trento, Trento, Italy
School of Law, Senshu Univ, Kanagawa, Japan 4Dept Biological Sci, Kyoto Univ, Kyoto, Japan
5
Dept Psychol, Sophia Univ, Tokyo, Japan1
3

Discussion（18:35）

Saori Yokoi
Faculty of Pharmaceutical Sciences, Hokkaido University

Symposium 1S05e

16:50-18:50

Room 5 (3F 302)

Recent Progress in Gonadal Steroid Action on the Modulation of Multiple
Brain Functions and Behaviors
Chairpersons：

Sonoko Ogawa ‌Lab Behavioral Neuroendocrinology, Faculty of Human Sciences, University of Tsukuba
Nandini Vasudevan ‌University of Reading, UK

Introduction Sonoko Ogawa
Lab Behavioral Neuroendocrinology, Faculty of Human Sciences, University of Tsukuba（16:50）
1S05e-1（16:55）

Non-genomic signaling by estrogens via the G-protein coupled estrogen receptor 1 (GPER1) are
important for social behaviours
Nandini Vasudevan，DeAsia Davis，Ruby Vajaria，Evangelos Delivopoulos
University of Reading, UK

1S05e-2（17:20）Latent Sex Differences in Acute Estradiol Modulation of Excitatory Synapses in the Hippocampus
Catherine S Woolley
Northwestern University

1S05e-3（17:45）

Sexual differentiation of calbindin neuron in the preoptic area
Shinji Tsukahara
Div Life Sci, Grad Sch Sci Engin, Saitama Univ, Saitama, Japan

1S05e-4（18:05）Innate immune cells are crucial regulators of hormonally-driven sexual differentiation of brain andmotivated behavior
Kathryn M Lenz
Dept. Psychology, Dept. Neuroscience, The Ohio State University, Columbus, Ohio, USA

1S05e-5（18:30）

The role of estrogen receptors in the regulation of male and female social behaviors.
Kazuhiro Sano，Tetsu Hatsukano，Sonoko Ogawa
Lab Behavioral Neuroendocrinology, Univ. of Tsukuba, Tsukuba city Japan111

Symposium 1S06e

16:50-18:50

Room 6 (2F 201A)

Whole brain physiology by a combination of fMRI and neurophysiology inrodents
Chairpersons：

Norio Takata ‌Keio University School of Medicine
Akira Sumiyoshi ‌NIDA-IRP, NIH

Introduction Norio Takata
Dept Neuropsychiatry, Keio Univ Sch of Med, Tokyo, Japan（16:50）
1S06e-1（16:55）

Exploring a relationship between resting state networks in the brain and a novel oscillatory activityof the thalamic reticular nucleus
Norio Takata
Dept Neuropsychiatry, Keio Univ Sch of Med, Tokyo, Japan

1S06e-2（17:18）Rat fMRI in combination with in vivo neurophysiological techniques
Akira Sumiyoshi1,2,3
National Institutes for Quantum and Radiological Science and Technology, Chiba, Japan
National Institute on Drug Abuse, National Institutes of Health, Baltimore, MD, USA
3
Institute of Development, Aging, and Cancer, Tohoku University, Sendai, Japan1
2

1S06e-3（17:41）Visualizing whole-brain activity in the mouse with functional Magnetic Resonance Imaging
Joanes Grandjean
Singapore Bioimaging Consoritum

1S06e-4（18:04）

Resting-state functional-connectivity investigation of the neural substrates of psychiatric disorders
Noriaki Yahata
Nat Inst of Radiol Sci, Nat Inst's for Quantum and Radiol Sci and Tech, Chiba, Japan

1S06e-5（18:27）

Circuits of depression in rodent functional connectivity MRI
Alexander Sartorius1，Wolfgang Weber-Fahr2，Natalia Gass2，Christian Clemm von Hohenberg2
Central Institute of Mental Health, Uni Heidelberg
Workgroup Translational Imaging, Dept. Neuroimaging, Central Institute of Mental Health, Mannheim, University of
Heidelberg
1
2

Symposium 1S07e

16:50-18:50

Room 7 (2F 201B)

New trends in study on plasticity-related gene Arc/arg3.1: regulations andcognitive functions
Sponsored by Grant-in-Aid‌for Scientific Research on Innovative Areas “Brain information
dynamics underlying multi-area interconnectivity and parallel processing”
Chairpersons：

Hiroyuki Okuno ‌Kagoshima University Graduate School of Medical and Dental Sciences
Kasia Radwanska ‌Nencki Institute of Experimental Biology of Polish Academy of Sciences

Introduction Hiroyuki Okuno1，Kasia Radwanska2
1
Kagoshima University Graduate School of Medical and Dental Sciences（16:50）

Nencki Institute of Experimental Biology of Polish Academy of Sciences

2

1S07e-1（16:52）

Arc/Arg3.1-driven regulation of activity-dependent AMPA receptor dynamics at active and inactive
synapses
Haruhiko Bito1,2，Yuichiro Ishii1，Hajime Fujii1，Takashi Hayashi1,3，Michiko Okamura1，Yayoi Kondo1，
Manabu Abe4，Kenji Sakimura4，Hiroyuki Okuno5
Dept Neurochem, Univ of Tokyo, Japan 2IRCN-WPI, Univ of Tokyo, Japan 3Natl Cntr Neurol Psychiat, Tokyo, japan
Brain Res Inst, Niigata Univ, Niigata, Japan 5Dept of Biochem Mol Biol, Kagoshima Univ Grad Sch Med Dent Sci.

14

1S07e-2（17:16）

Arc protein structure and oligomerization control: from synaptic plasticity to retroviral-like capsids
Clive Bramham
University of Bergen112

NEURO2019

1S07e-3（17:40）The Temporal Dynamics of Arc Expression Regulate Cognitive Flexibility
Angela M Mabb
Georgia State University, Atlanta, United States

1S07e-4（18:04）

The role of Arc/Arg3.1 protein in the regulation of alcohol seeking
Kasia Radwanska

1S07e-5（18:28）

Symposium
July 25

Nencki Institute of Experimental Biology, PAS

Arc deficiency causes impairment in memory precision and cognitive switching
Hiroyuki Okuno
Dept. of Biochem and Mol Biol, Kagoshima Univ, Kagoshima, Japan

Symposium 1S10e

16:50-18:50

Room 10 (Bandaijima Building 6F Meeting Room)

The future of glia research viewed by young glial researchers

Wakate Dojo Symposium

Chairpersons：

1S10e-1（16:50）

Yoshinori Otani ‌Faculty of Medicine, Shimane University
Yuki Fujita ‌Osaka University

Glia world: Frontier of the brain science developed by Ca2+ imaging
Yoshihisa Kudo
Hachioji Med.Center, Tokyo Med. Univ. Hachioji, Tokyo, Japan

1S10e-2（17:10）Astrocytes and meta-communication keep the brain healthy
Hiromu Monai1,2
Ochanomizu Univ, Tokyo, Japan
Lab. for Neuron-Glia Circuitry, RIKEN CBS

1
2

1S10e-3（17:38）

Neuroprotective function of microglia in the developmental brain
Yuki Fujita1,2，Toru Nakanishi1,3，Masaki Ueno4，Toshihide Yamashita1,2,3,5Dept. of Molecular Neuroscience, Grad. Sch. of Medicine, Osaka Univ., Osaka, JapanWPI Immunology Frontier Research Center, Osaka Univ., Osaka, Japan
3
Grad Sch of Frontier Biosci, Osaka Univ, Osaka, Japan 4Brain Research Inst., Niigata Univ., Niigata, Japan
5
Neuro-Medical Science, Grad. Sch. of Medicine, Osaka Univ., Osaka, Japan12

1S10e-4（18:06）

Control of myelin formation and function by translational readthroughYoshinori Otani1,2，Nobuhiko Ohno3，Yoshihide Yamaguchi1，Jing-Jing Cui1，Hiroko Baba1
Department of Molecular Neurobiology, Tokyo University of Pharmacy and Life Sciences, Hachioji, Japan
Faculty of medicine, Department of Anatomy and Neuroscience, Shimane University, Izumo, Japan3
Department of Anatomy, Division of Histology and Cell Biology, School of Medicine, Jichi Medical University, Shimono, Japan1
2

Discussion（18:34）113

SymposiumDay 2 - July 26

Symposium 2S01m

8:30-10:30

Room 1 (4F International Conference Room)Breakthroughs to be made for the next Brain Science*in Japanese

The President of the Annual Meeting - organized symposia

Organizers：

Hitoshi Okamoto ‌RIKEN Center for Brain Science
Hiroyuki Nawa ‌Brain Research Institute, Niigata University

Chairpersons：

Hitoshi Okamoto ‌RIKEN Center for Brain Science
Teruhiro Okuyama ‌The University of Tokyo

Introduction Hitoshi Okamoto
Lab. for Neural Circuit Dynamics of Decision Making, RIKEN CBS（8:30）
2S01m-1（8:33）

Systemic environment regulates central nervous system regeneration
Rieko Muramatsu
National Center for Neurology and Psychiatry, Kodaira, Japan

2S01m-2（8:50）Breakthroughs in Alzheimer's disease research
Kei Igarashi
Univ of California Irvine, Irvine, USA

2S01m-3（9:07）

Lessons from research in artificial intelligence
Hiroshi Makino
Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore

2S01m-4（9:24）

Spatio-Temporal resolution issues for “observation” and “manipulation”
Teruhiro Okuyama
Inst Quantitative Biosciences (IQB), Univ of Tokyo, Tokyo, Japan

2S01m-5（9:41）

Toward comprehensive understanding of the brain-wide neuronal network and beyond
Fumi Kubo
National Inst. of Genetics, Mishima, Japan

2S01m-6（9:58）

Exploring biological basis of Self
Yutaka Komura
Kokoro Res Ctr, Kyoto Univ, Kyoto

Discussion（10:15）
Symposium 2S02m

8:30-10:30

Room 2 (2F Main HallA)

The Addicted brain-From substance abuse to gambling and gaming disorders



ISN/JSN Joint Symposium

Chairpersons：Akio Wanaka ‌Department of Anatomy and Neuroscience, Nara Medical University
Andrew J Lawrence ‌Florey Institute of Neuroscience & Mental Health, Melbourne Brain Centre,
University of Melbourne

Introduction Akio Wanaka1，Andrew Lawrence2
1
Department of Anatomy and Neuroscience, Nara Medical University（8:30）
Florey Institute of Neuroscience & Mental Health2

2S02m-1（8:35）

Neural mechanisms underlying stress-induded enhancement of cocaine craving
Katsuyuki Kaneda
Lab Mol Pharmacol, Kanazawa Univ

114

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2S02m-2（9:03）

Identifying novel therapeutic targets for relapse prevention
Andrew Lawrence
Florey Institute of Neuroscience & Mental Health

2S02m-3（9:31）

Goal-directed versus Stimulus-driven control in Gaming Disorders
Young-Chul Jung1,2
Yonsei University College of Medicine, Department of Psychiatry
Yonsei University College of Medicine, Institute of Behavioral Science in Medicine

1
2

2S02m-4（9:59）

Neuroimaging of gambling disorder
Hidehiko Takahashi
Dept. Psychiatry and Behavioral Sciences, Tokyo Med Dent Univ, Tokyo, Japan

Symposium 2S03m

8:30-10:30

Room 3 (2F Main HallB)

Being Adaptive: The Role of Metacognition in Learning and Guiding Behavior

Sponsored by ERATO Ikegaya BRAIN-AI Hybrid Project

Chairpersons：

Aurelio Cortese ‌ATR Institute International
Mahiko Konishi ‌Ecole Normale Superieure, Paris, France

Introduction Mahiko Konishi
Ecole Normale Superieure（8:30）
2S03m-1（8:35）

What optimal and suboptimal metacognitive computations can tell us about adaptive behavior
Megan Peters
University of California Riverside

2S03m-2（9:00）

Metacognitive control of sensory evidence accumulation
Tarryn Balsdon1,2，Valentin Wyart2，Pascal Mamassian1
LSP, DEC, ENS, PSL University, CNRS, Paris, France

1

2S03m-3（9:25）

LNC, DEC, ENS, PSL University, INSERM, Paris, France

2

Metacognition is spared in a dual-task visual paradigm
Mahiko Konishi1，Clemence Compain1，Jerome Sackur1，Vincent de Gardelle2
Ecole Normale Superieure
Paris School of Economics and CNRS

1
2

2S03m-4（9:50）

Metacognition simplifies reward-based learning in complex, uncertain scenarios
Aurelio Cortese1，Hakwan Lau2,3，Mitsuo Kawato1
ATR Computational Neuroscience Lab, Kyoto, Japan
Dept. of Psychology, UCLA, Los Angeles, USA

1
3

Discussion（10:15）

Dept. of Psychology, Univ of Hong Kong, Hong Kong

2

Aurelio Cortese1，Mahiko Konishi2
ATR Computational Neuroscience Lab, Kyoto, Japan
Ecole Normale Superieure

12

Symposium 2S04m

8:30-10:30

Room 4 (3F 301)

Singularity Brain Science – toward discovery of singularity in brain system bymassive trans-scale imaging –Chairpersons：

2S04m-1（8:30）

Hiroko Bannai ‌Dept Physiol, Keio Univ Sch of Medicine, Tokyo, Japan
Takeharu Nagai ‌ISIR, Osaka Univ

What is "Singularity Biology"?
Takeharu Nagai
ISIR, Osaka Univ

115

Symposium
July 26

Discussion（10:27）

2S04m-2（8:53）

Approach to neurodegenerative disease by singularity biology
Hiroko Bannai1,2，Michio Hiroshima3，Akihiko Takashima4
Dept Physiol, Keio Univ Sch of Medicine, Tokyo, Japan
Faculty Sci, Gakushuin Univ, Tokyo, JapanJST ERATO, Saitama, Japan

1

2

4

2S04m-3（9:16）RIKEN BDR, Osaka, Japan

3

High-speed and scalable whole-brain imaging for finding singularity in the brain
Kaoru Seiriki1,2，Atsushi Kasai1，Takanobu Nakazawa1,3，Hitoshi Hashimoto1,4,5,6
Grad. Sch. of Pharmaceutical Sciences, Osaka Univ.,Osaka, Japan
Inst. Transdisciplinary Grad. Degree Programs, Osaka Univ., Osaka, Japan
3
Dept Pharmacol., Grad. Sch. of Dentistry, Osaka Univ., Osaka, Japan4
Mol Res Cent for Child Mental Development, United Grad Sch of Child Development, Osaka-Kanazawa-Hamamatsu Univ Sch
Med, Osaka
5
Div. Biosci., Inst. Datability Sci., Osaka Univ., Osaka, Japan
6
Transdimensional Life Imaging Div., Inst. Open and Transdisciplinary Res. Initiatives, Osaka Univ. Osaka, Japan1
2

2S04m-4（9:39）

A challenging imaging technology for singularity brain science
Tomonobu Watanabe
Lab. for Comprehensive Bioimaging, RIKEN BDR

2S04m-5（10:22）

Near-infrared upconversion optogenetics and nanoscopy
Shuo Chen1,2，Xiaogang Liu3，Thomas J McHugh2
Hellen Wills Neuroscience Institute, University of California, Berkeley 2Lab. for Circuit and Behavioral Physiol., RIKEN CBS
Department of Chemistry, National University of Singapore, Singapore

13Discussion（10:25）

Takeharu Nagai
ISIR, Osaka Univ

Symposium 2S05m

8:30-10:30

The dawn of data- and model-driven neuroscience

Room 5 (3F 302)

Sponsored by MEXT‌
Grant-in-Aid for Scientific Research on Innovative Areas "Systems Scienceof Bio-navigation"
Chairpersons：

2S05m-1（8:30）

Kotaro Kimura ‌Nagoya City University
Junichi Nakai ‌Saitama University

Toward data-driven scientific discovery: an example in functional protein design for neuroscience
researchIchiro takeuchi1,2
Dept Computer Science, Nagoya Institute of Technology, Nagoya, Japan1

2S05m-2（9:00）

Center for Advanced Intelligence Project, RIKEN

2

Deep learning-aided knowledge discovery from animal behavioral data
Takuya Maekawa
Osaka Univ.

2S05m-3（9:30）

Mapping the neural substrates of behavior using machine learning
Alice A. Robie，Branson Kristin
HHMI Janelia Research Campus

2S05m-4（10:00）Data-driven predictive models for information processing in the (small) brain
Chentao Wen1，Kotaro Kimura1,2
Grad Sch Natural Sci, Nagoya City Univ, Aichi, Japan

1

116

RIKEN AIP, Tokyo, Japan

2

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Symposium 2S06m

Neurobiology of emotional communication in rodents
Chairpersons：

2S06m-1（8:30）

8:30-10:30

Room 6 (2F 201A)

Yasushi Kiyokawa ‌Laboratory of Veterinary Ethology, The University of Tokyo
Julen Hernandez-Lallement ‌Social Brain Lab, Netherlands Institute for Neuroscience

Alarm and appeasing pheromones in rat
Yasushi Kiyokawa
Lab Vet Etho, Univ of Tokyo, Tokyo

2S06m-2（9:00）

Oxytocin-Dependent Emotion Recognition in Mice
Francesca Manago，Francesco Papaleo
Istituto Italiano di Tecnologia

Symposium
July 26

2S06m-3（9:30）

Behavioral and Neural Dynamics of Prosocial Behavior in Rats
Julen Hernandez-Lallement1，Valeria Gazzola1,2，Christian Keysers1,2
Social Brain Lab, Netherlands Institute of Neuroscience, The Netherlands
Dept. of Psychology, Univ. of Amsterdam, Amsterdam, The Netherlands

1
2

2S06m-4（10:00）The neural basis of social choice in rats
Sander van Gurp1，Marijn van Wingerden1,2，Douman Seidisarouei1，Mireille van Berkel1，
Tobias Kalenscher1
Heinrich-Heine University, Duesseldorf, Germany

1

Tilburg University, Tilburg, the Netherlands

2

Symposium 2S02a

15:10-17:10

Room 2 (2F Main HallA)

Towards understanding how objects are perceived in our brain

The Annual Meeting - Organized Symposium

Chairpersons：

Hidehiko Komatsu ‌Tamagawa University
Isao Hasegawa ‌Niigata University

Introduction Hidehiko Komatsu
Tamagawa University（15:10）
2S02a-1（15:15）

Joint encoding of shape and surface properties in mid-level ventral visual cortex
Anitha Pasupathy1,2，Taekjun Kim1,2，Dina V Popovkina3，Wyeth Bair1,2
Dept. of Biological Structure, University of Washington
Dept. of Psychology, University of Washington

1
3

2S02a-2（15:40）

Washington National Primate Research Center

2

Distributed neural organization for object vision/memory revealed with electrocorticography
Isao Hasegawa
Dept Physiol, Niigata Univ Sch Med, Niigata, Japan

2S02a-3（16:05）

How are priors and likelihood combined during object recognition?
Floris P de Lange
Radboud University Nijmegen, Netherlands

2S02a-4（16:30）Color: a tool to understand the organization and operation of the ventral visual pathway
Bevil Conway
National Institutes of Health (USA)Discussion（16:55）117

Symposium 2S03a

15:10-17:10

Room 3 (2F Main HallB)

Bridging emotion and decision making: a view through neural circuitsThis symposium is held as part of a RIKEN symposium

Chairpersons：

2S03a-1（15:10）

Joshua Patrick Johansen ‌RIKEN Center for Brain Science
Anatol Kreitzer ‌Gladstone Institutes/UCSF

The nature of dopamine signals during spatial navigation
Naoshige Uchida
Harvard University

2S03a-2（15:34）Prefrontal-thalamic pathways involved in emotional regulation
Stephen Maren
Texas A&M University

2S03a-3（15:58）

Cerebral and systemic integration mechanisms to elicit the crisis-response state
Reiko Kobayakawa，Ko Kobayakawa
Kansai Medical University

2S03a-4（16:22）Function of Basal Ganglia Circuitry in Motivation and Decision Making
Anatol C Kreitzer
Gladstone Institutes/UCSF

2S03a-5（16:46）

Parallel brainstem-to-amygdala projections control aversive emotional learning
Joshua P. Johansen
RIKEN Center for Brain Science

Symposium 2S04a

15:10-17:10

Room 4 (3F 301)

Brain network dysfunction in Alzheimer's disease: a new potential target for
future therapy
Chairpersons：Kei Igarashi ‌University of California, Irvine
Abid Hussaini ‌Columbia University

Introduction Kei M Igarashi1,21Department of Anatomy & Neurobiology, University of California, Irvine（15:10）
2S04a-1（15:13）

JST PRESTO

2

New Approaches to Alzheimer’s: From Neural Deficits to Neural Stimulation
Annabelle C Singer
Georgia Institute of Technology & Emory University

2S04a-2（15:43）

Network abnormalities and interneuron dysfunction in Alzheimer disease
Jorge J Palop
University of California, San Francisco; Gladstone Institutes

2S04a-3（16:13）

Identifying neurons in the brain most vulnerable to Alzheimer's disease
Abid Hussaini
Columbia University Medical Center

2S04a-4（16:43）

Impaired neural representation and gamma oscillations in the entorhinal-hippocampal circuit ofknock-in Alzheimer model
Kei M Igarashi1,2Department of Anatomy & Neurobiology, University of California, Irvine

1

118

JST PRESTO

2

NEURO2019

Symposium 2S05a

New trends in neruoimmunology



15:10-17:10

Room 5 (3F 302)

Symposium Organized by the Recipient of the 5th JSN Distinguished Investigator Award

Chairpersons：Takashi Shichita ‌Tokyo Metropolitan Institute of Medical Science
Kazuhiro Suzuki ‌Osaka University

Introduction Takashi Shichita
Tokyo Metropolitan Institute of Medical Science（15:10）
2S05a-1（15:15）Control of lymphocyte behaviors by adrenergic nerves
Kazuhiro Suzuki
Immunology Frontier Research Center, Osaka University, Osaka, Japan

Symposium
July 26

2S05a-2（15:35）

Excessive T cell activation in the absence of PD-1 affects behavior
Sidonia Fagarasan
RIKEN

2S05a-3（15:55）In situ imaging of monoamine localization and dynamics by mass spectrometry
Yuki Sugiura
Dept. Biochem, Sch of Med, Keio Univ, Tokyo

2S05a-4（16:15）

Dynamic homeostasis of epidermal sensory nerves and its breakdown during skin inflammation
Takaharu Okada1,2
Lab for Tissue Dynamics, RIKEN IMS

1

2S05a-5（16:35）

Grad School of Med Life Sci, Yokohama City Univ, Yokohama, Japanb

2Modulation of somatosensory information processing by the CNS immune cells microglia
Makoto Tsuda
Dept Life Innov, Grad Sch Pharm Sci, Kyusyu Univ, Fukuoka, Japan

2S05a-6（16:55）

Role of the innate immune system in cerebral post-ischemic sterile inflammation
Jun Tsuyama，Takashi Shichita
Stroke Renaissance, Tokyo Metro. Inst. Med. Sci.

Symposium 2S06a

Voltage imaging: What's New?
Chairpersons：

2S06a-1（15:10）

15:10-17:10

Room 6 (2F 201A)

Bernd Kuhn ‌OIST Graduate University
Takashi Tominaga ‌Tokushima Bunri University

Simultaneous dendritic voltage and calcium imaging and somatic recording from Purkinje neurons inawake mice
Bernd Kuhn，Christopher J. Roome
Okinawa Institute of Science and Technology Graduate University

2S06a-2（15:34）

Uncovering functional development of the cerebellum by voltage imaging in zebrafish
Sachiko Tsuda
Grad Sch Sci Engin, Saitama Univ, Saitama, Japan

2S06a-3（15:58）Genetically encoded voltage indicators and their application
Masayuki Sakamoto
Grad Sch of Med, Univ Tokyo, Tokyo, Japan

2S06a-4（16:22）

Specialization of a voltage indicator for detection of subthreshold potentials towards dual voltage
and calcium imaging in vivo.
Yuki Bando
Dept. Organ and Tissue Anatomy, Hamamatsu Univ. Sch. Medicine

1192S06a-5（16:46）

Optical recording of the real-time in vitro neural circuit dynamics: the voltage-sensitive dye (VSD)
imaging and the fast intrinsic optical signal (FIOS)
Takashi Tominaga，Yoko Tominaga
Inst. Neurosci., Tokushima Bunri Univ., Kagawa, Japan

Symposium 2S07a

15:10-17:10

A new era of neuroscience with zebrafish
Chairpersons：

2S07a-1（15:10）Koichi Kawakami ‌National Institute of Genetics
Masahiko Hibi ‌Bioscience and biotechnology center, Nagoya Univ

Development and function of zebrafish cerebellar neural circuitry
Masahiko Hibi1,2，Tsubasa Itoh1，Shinnosuke Yura1，Koji Matsuda1,2，Takashi Shimizu1,2Div. of Biological Science, Grad. Sch. of Science, Nagoya Univ.

1

2S07a-2（15:30）

Room 7 (2F 201B)

Bioscience and Biotechnology Center, Nagoya Univ., Nagoya

2

Spinal V1 neurons ensure selective patterns of motor neuron recruitment during locomotion
Shin-ichi Higashishima，Yukiko Kimura
National Institutes of Natural Sciences, ExCELLS

2S07a-3（15:50）

Neuronal architecture of a visual center that processes optic flow
Fumi Kubo
National Inst. of Genetics, Mishima, Japan

2S07a-4（16:10）

Neural circuit mechanisms underlying olfactory memory and motivated behavior in zebrafish
Nobuhiko Miyasaka1，Yoshihiro Yoshihara1,2
Lab. for Systems Mol. Ethology, RIKEN CBS

1

2S07a-5（16:30）RIKEN CBS-KAO Collaboration Center (BKCC), RIKEN CBS

2

Future state prediction errors guide active avoidance behavior by adult zebrafish.
Makio Torigoe1，Tanvir Islam1,4，Hisaya Kakinuma1,4，Chi Chung Alan Fung2，Takuya Isomura3，
Hideaki Shimazaki3，Tazu Aoki1，Tomoki Fukai2，Hitoshi Okamoto1,4Lab. for Neural Circuit Dynamics of Decision Making, RIKEN CBS 2Lab. for Neural Coding and Brain Computing, RIKEN CBS
Lab. for Neural Computation and Adaptation, RIKEN CBS 4RIKEN CBS-KAO Collaboration Center (BKCC), RIKEN CBS

1
3

2S07a-6（16:50）

The amygdalar and hippocampal functions in zebrafish
Koichi Kawakami1,2
Lab. of Molec. and Dev. Biol., National Inst. of Genetics, Mishima, Japan

1

120

Dept. of Genetics, SOKENDAI

2

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SymposiumSymposium 3S01m

Day 3 - July 27
8:45-10:45

Room 1 (4F International Conference Room)

Exploring the origin of brain and central nervous system through monitoring
the neural activity of the whole animal
Chairpersons：Yuichi Iino ‌Department of Biological Sciences, Graduate School of Science, The University of Tokyo
Rafael Yuste ‌Departments of Biological Sciences and Neuroscience , Columbia University

Introduction Yuichi Iino
Department of Biological Sciences, Graduate School of Science, The University of Tokyo（8:45）
3S01m-1（8:47）

Origin of Central Nervous System implied by behavioral analysis and visual monitoring of neuralactivity in Hydra a member of phylum Cnidaria
Hiroshi Shimizu1，Yukihiko Noro2，Katsuhiko Mineta1，Takashi Gojobori1
King Abdullah Univeristy of Science and Technology

1

Breaking the Neural Code of a CnidarianRafael Yuste

Symposium
July 27

3S01m-2（9:08）

Faculty of Science and Engineering Waseda University

2

Columbia University

3S01m-3（9:33）

Exploring the information processing of neural network through whole-brain activity-imaging of C.
elegans
Yu Toyoshima1，Hirofumi Sato1，Manami Kanamori1，Stephen Wu2，Moon-Sun Jang1，Yuko Murakami3，
Suzu Oe3，Terumasa Tokunaga4，Osamu Hirose5，Sayuri Kuge3，Takayuki Teramoto3，Yuishi Iwasaki6，
Ryo Yoshida2，Takeshi Ishihara3，Yuichi Iino1
Dept Biol Sci, Univ of Tokyo, Tokyo, Japan
Inst. of Statistical Mathematics, Research Organization of Information and Systems, Tokyo, Japan
Dept. of Biol., Facl. of Sci., Kyushu Univ, Fukuoka, Japan
4
Dept of Systems Design and Informatics, Facl of Computer Science and Systems Engineering, Kyushu Inst of Technology.
Fukouka, Japan
5
Faculty of Biological Science and Technology, Inst of Science and Engineering, Kanazawa Univ., Ishikawa, Japan
6
Dept. of Mechanical Systems Engineering, College of Engineering, Ibaraki Univ., Ibaraki, Japan1
2
3

3S01m-4（9:56）

Embryonic development of the motor circuits in Drosophila : emergence of coordinated neuralactivities and the role of sensory feedback
Akinao Nose1,2，Xiangsunze Zeng1，Tappei Kawasaki1，Kengo Inada3，Hokto Kazama3
Dept. Comp Sci Eng, Univ Tokyo, Kashiwa, Japan 2Dept. Physics, Univ Tokyo, Tokyo
Lab. for Circuit Mechanisms of Sensory Perception, RIKEN CBS

1
3

3S01m-5（10:19）Visualization of neuronal activity in prey capture behaviour in zebrafish larvae
Akira Muto
National Institute of Genetics, Molecular and Developmental Biology

Summary（10:42）Rafael Yuste
Columbia University

Symposium 3S02m

8:45-10:45

Room 2 (2F Main HallA)

Dissecting neural circuit basis of depression and bipolar disorder
Chairpersons：

3S02m-1（8：45）

Tadafumi Kato ‌RIKEN Center for Brain Science
Hidenori Aizawa ‌Dept Neurobiol, Sch Biomed Health Sci, Hiroshima Univ, Japan

Role of raphe nuclei and paraventricular thalamic nucleus in animal models of bipolar disorder
Mie Kubota-Sakashita，Tadafumi Kato
Lab for Mol Dynam Mental Disord, RIKEN CBS, Saitama, Japan

3S02m-2（9:10）

Deciphering the heterogeneous symptoms of depression by the habenular pathways
Hidenori Aizawa
Dept Neurobiol, Sch Biomed Health Sci, Hiroshima Univ, Japan

121

3S02m-3（9:35）

Molecular and neural mechanisms of stress susceptibility and resilience
Shusaku Uchida
SK Project, MIC, Kyoto Univ Grad Sch of Medicine, Kyoto, Japan

3S02m-4（10:00）Brain-wide neural oscillatory networks predict depression vulnerability
Rainbo Hultman
University of Iowa

Discussion（10:25）
Symposium 3S03m

Linking Neural Circuits and Function to Behaviour
Chairpersons：

8:45-10:45

Room 3 (2F Main HallB)

Roger Marek ‌Queensland Brain Institute, The University of Queensland, AU
Angelo Tedoldi ‌Queensland Brain Institute, The University of Queensland, AU

Introduction Neural circuit that drives fear and its extinction（8:45）
Roger Marek
The University of Queensland

3S03m-1（8:50）

VCAM1 Label a Subpopulation of Neural Stem Cells in Adult Hippocampus and Functional Link to
Spatial Memory
Xiao-Ling Hu1,2，Dan-Ying Wang1,2，An-Feng Luo1,2，Qing-Ran Bai4，Qin Shen4，Xiao-Min Wang1,2,3
School of Basic Medical Sciences, Capital Medical University, Beijing 100069, China;
Beijing Key Laboratory of Neural Regeneration and Repair, Capital Medical University, Beijing 100069, China;
3
Beijing Institute for Brain Disorders, Beijing 100069, China;
4Brain and Spinal Cord Innovative Research Center of Tongji Hospital, School of Life Sciences and Technology Tongji
University, Shanghai 200065, China
1
2

3S03m-2（9:15）

Linking emotion to motion: an open cortico-basal ganglia loop allows limbic control over motor
outputSho Aoki1,2,3,4，Jared B Smith1，Hao Li1，Xunyi Yan1，Masakazu Igarashi2,4，Patrice Coulon5，
Jeffery R Wickens2，Tom JH Ruigrok3，Xin Jin1
Salk Institute for Biological Studies 2Okinawa Inst. of Science and Technology 3Erasmus Medical Center Rotterdam
Japan Society for the Promotion of Science 5Institut des Neurosciences de la Timone

1
4

3S03m-3（9:45）

Neural circuit that drives fear and its extinction
Roger Marek
The University of Queensland

3S03m-4（10:10）Ketamine, burst, glia and depression
Yan Yang，Hui Yi Cui，Ning Kang Sang，Yan Yi Dong
Zhejiang University

Discussion（10:35）
Symposium 3S04m

8:45-10:45

Room 4 (3F 301)

New modes of neuronal translation regulation in health and disease
Chairpersons：

3S04m-1（8:45）

Motomasa Tanaka ‌RIKEN CBS
Aaron Gitler ‌Stanford University School of Medicine

Targeting RAN proteins improves phenotypes in C9orf72 BAC ALS/FTD mice
Laura Ranum1，Lien Nyguen2，Fabio Montrasio3，Olgert Bardhi2，Shu Guo2，Solaleh Khoramian Tusi2，
Katsuya Nakamura2，Monica Banez Coronel2，Nahum Sonenberg4，Jan Grimm3，Tao Zu2
Center for NeuroGenetics, Department of Molec. Genet. Microb. University of Florida
Center for NeuroGenetics, University of Florida 3Neurimmune AG 4McGill University

1
2

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3S04m-2（9:10）

Epitranscriptomics in Synapses
Dan Ohtan Wang1，Kei Iida2，Ikumi Oomoto1，Belinda Goldie3，Kelsey Martin4，Matteo Pelligrini4
iCeMS, Kyoto University 2Kyoto University, School of Medicine
University of California, Los Angles, USA

1
4

3S04m-3（9:35）

Monash University, Australia

3

RNG105 (caprin1) establishes dendritic mRNA localization and is essential for long-term memory
formation
Nobuyuki Shiina1,2,3
National Inst. for Basic Biology, Aichi, Japan1

3S04m-4（10:00）ExCELLS

2

The Grad. Univ. for Advanced Studies (SOKENDAI), Okazaki, Japan

3

Impaired mRNA translation and mental function by protein aggregation in neuropsychiatric disorders
Motomasa Tanaka
Lab. for Protein Conformation Diseases, RIKEN CBS

3S04m-5（10:20）

RPS25 regulates RAN translation of C9orf7 2 repeat expansions
Aaron D. Gitler
Stanford University

8:45-10:45

Brain-state dynamics underlying consciousness and cognition
Chairpersons：

3S05m-1（8:45）

Room 5 (3F 302)

Sakiko Honjoh ‌University of Tsukuba, International Institute for Integrative Sleep Medicine
Akihiro Yamanaka ‌Nagoya University, Department of Neuroscience II

Functional identification involved in the regulation of sleep/wakefulness brain state change
Akihiro Yamanaka
Res Inst Envron Med, Nagoya Univ

3S05m-2（9:05）

Hippocampal information processing across sleep/wake cycles
Kenji Mizuseki
Osaka City University Graduate School of Medicine, Osaka, Japan

3S05m-3（9:25）

Consciousness and Brain Complexity: an exploration across scales and models
Marcello Massimini
University of Milan

3S05m-4（9:55）

Vigilance state-dependent thalamocortical activity dynamics
Sakiko Honjoh
International Institute for Sleep Medicine, Univ of Tsukuba, Tsukuba, Ibaraki, Japan

3S05m-5（10:15）Single Neuron Studies of the Preconscious Self
Itzhak Fried
University of California, Los Angeles, Department of Neurosurgery

Symposium 3S06m

8:45-10:45

Room 6 (2F 201A)

Neuro-Immune Crosstalk: Its role in the pathogenesis and perspectives fornovel therapies
Chairpersons：

Makoto Urushitani ‌Department of Neurology, Shiga University of Medical Science
Takashi Yamamura ‌National Institute of Neuroscience, NCNP

Introduction Takashi Yamamura
National Institute of Neuroscience, NCNP
（8:45）
3S06m-1（8:49）

Using the brain to boost immunity and fight cancer
Asya Rolls
Technion- Israel Institute of Technology

123

Symposium
July 27

Symposium 3S05m

3S06m-2（9:18）

Immunological aspects of a possible biomarker and therapeutic target for secondary progressive
multiple sclerosis
Shinji Oki
Dept. Immunol., National Center of Neurology and Psychiatry, National Inst. of Neuroscience

3S06m-3（9:47）

Elimination of TDP-43 inclusions linked to amyotrophic lateral sclerosis by a misfolding-specificintrabody
Makoto Urushitani
Dept Neurol, Shiga Univ of Med Sci

3S06m-4（10:16）Harnessing the immune system to combat age-related dementia and Alzheimer’s disease
Michal Schwartz
Neurobiology, Weizmann Institute of Science

Symposium 3S02a

14:20-16:20

Room 2 (2F Main HallA)

Neuroinflammation and the Blood Brain Interface: New findings in brain
pathology
Chairpersons：Atsuyoshi Shimada ‌Kyorin University Faculty of Health Sciences
Keith W. Kelley ‌Department of Animal Sciences in College of ACES, University of Illinois at UrbanaChampaign

Introduction Keith W. Kelley
Department of Animal Sciences in College of ACES, University of Illinois at Urbana-Champaign（14:20）
3S02a-1（14:25）

Regulating Neurological Disorders via the Meningeal Lymphatic System
Antoine Louveau1，Jonathan Kipnis2
Lerner Research Institute Cleveland Clinic

1

3S02a-2（14:55）

University of Virginia

2

The Neuroimmune Axes of the Blood-brain Interface
William Allen Banks
Veterans Affairs and U of Washington - Seattle

3S02a-3（15:25）Meningeal and capillary mediation of brain inflammation
Mike Dragunow
University of Auckland

3S02a-4（15:55）

Histological architecture underlying brain-immune cell-cell interactions
Atsuyoshi Shimada
Kyorin University Faculty of Health Sciences

Symposium 3S03a

14:20-16:20

Room 3 (2F Main HallB)

Novel circuits for the control of emotion linked with psychiatric disorders
Chairpersons：

Satoshi Kida ‌Department of Bioscience, Tokyo University of Agriculture
Mazen Kheirbek ‌Department of Psychiatry, University of California San Francisco

Introduction Satoshi Kida
Dept. of Bioscience, Tokyo Univ. of Agriculture,Tokyo（14:20）
3S03a-1（14:21）Dissecting Locus Coeruleus Noradrenergic Circuits in Stress and Anxiety
Michael R Bruchas1，Andrew Luskin1，Kelsey Barcomb2，Chris Ford2
University of Washington

1

3S03a-2（14:45）

University of Colorado - Denver2

Regulation of reconsolidation and extinction by fear memory engrams
Satoshi Kida
Dept. of Bioscience, Tokyo Univ. of Agriculture,Tokyo

124

NEURO2019

3S03a-3（15:08）Prefrontal cortex and midline thalamic output circuits guide reward seeking through divergent cue
encoding
Garret Stuber
University of Washington

3S03a-4（15:32）

Neural Circuit Mechanism of Social Hierarchy
Hailan Hu
Zhejiang University

3S03a-5（15:56）

Memory codes in the dentate gyrus
Mazen Kheirbek
University of California, San Francisco

Symposium 3S04a

14:20-16:20

Room 4 (3F 301)

Non-linguistic bases of language and its acquisition: Music, Mathematics,
Executive Function, Information Technology, and Social Cognition
Chairpersons：Auditory processing and second language acquisition
Adam Tierney1，Magdalena Kachlicka1，Hui Sun1，Kazuya Saito2
Birkbeck College

1

3S04a-2（14:50）Symposium
July 27

3S04a-1（14:20）Motoaki Sugiura ‌Tohoku University
Adam Tierney ‌Birkbeck, University of London

University College London

2

Neural mechanisms of hierarchical structure building in language and mathematics
Michiru Makuuchi
National Rehabilitation Center for Persons with Disabilities

3S04a-3（15:20）

Neurocognitive Correlates of Scientific Text Comprehension: Individual Differences in Executive
Functions, Electronic Device Usage and Reading Habits
Chun-Ting Hsu1,2，Roy Clariana3，Benjamin Schloss2，Ping Li2
Kyoto University 2Dept Psychology, Pennsylvania State University, USA
Dept Learning and Performance Systems, Pennsylvania State University, USA

1
3

3S04a-4（15:50）

The role of social cognition in language learning
Hyeonjeong JeongTohoku University

Symposium 3S05a

14:20-16:20

Room 5 (3F 302)

Molecular mechanisms for making species-specific neuronal circuits

Sponsored by Grant-in-Aid‌for Scientific Research on Innovative Areas “Interplay ofdevelopmental clock and extracellular environment in brain formation”
Chairpersons：Tadashi Nomura ‌Developmental Neurobiology, Kyoto Prefectural University of Medicine
Chiaki Ohtaka-Maruyama ‌Tokyo Metropolitan Institute of Medical Science

Introduction Patterns of neuronal migration and the evolution of mammalian-type neocortical architecture（14:20）Tadashi Nomura
Dev Neurobiol. Kyoto Pref Univ Med

3S05a-1（14:25）

Patterns of neuronal migration and the evolution of mammalian-type neocortical architecture
ＴａｄａｓｈｉNomuraDev Neurobiol. Kyoto Pref Univ Med

3S05a-2（14:48）The neural basis underlying species-specific courtship behavior in Drosophila subobscura
Ryoya Tanaka1，Tomohiro Higuchi2,3，Soh Kohatsu3，Kosei Sato3，Takeshi Awasaki4，
Daisuke Yamamoto3
Nagoya University

1

Tohoku University

2

Advanced ICT Research Institute3

Kyorin University

41253S05a-3（15:11）

A novel function of subplate neurons in radial migration and its implication in the evolution of
mammalian neocortical layer structure
Chiaki Maruyama
Neural Network Project, Tokyo Metropolitan Inst. of Medical Science, Tokyo, Japan

3S05a-4（15:34）

Mechanisms regulating the formation of commissural projections in human, mouse and marsupial
brain development
Linda J Richards1,2，Rodrigo Suarez1，Tobias Bluett1，Annalisa Paolino1，Laura R Fenlon1，
Laura Morcom1，Ilan Gobius1，Peter Kozulin1，Ryan Dean1，Timothy J Edwards1,3
The University of Queensland, Queensland Brain Institute
The University of Queensland, Faculty of Medicine

1
3

3S05a-5（15:57）

The University of Queensland, School of Biomedical Sciences

2

CORTICAL LAYER WITH NO KNOWN FUNCTION
Zoltan Molnar
University of Oxford

Symposium 3S06a

14:20-16:20

Room 6 (2F 201A)

Retinal plasticity over time scales: Hibernation, circuit reorganization, andsynaptic modulation



Sponsored by Center for Systems Vision Science
Ritsumeikan University/Ritsumeikan Global Innovation Research Organization
MEXT-Supported Program for the Strategic Research Foundation at Private Universities

Chairpersons：

Chieko Koike ‌Ritsumeikan University, School of Pharmaceutical Science
Steve DeVries ‌Northwestern University, Feinberg School of Medicine

Introduction Chieko Koike
Northwestern University（14:20）
3S06a-1（14:25）

Seeing in the cold – vision and hibernation
Wei LiNational Institutes of Health, NIH

3S06a-2（14:55）

Restoration of selective connectivity in adult mammalian retina
Alexander Sher
Santa Cruz Institute for Particle Physics, University of California Santa Cruz

3S06a-3（15:25）

Mechanisms of fast adaptation at the mammalian cone photoreceptor synapse
Steven H DeVries
Northwestern University

3S06a-4（15:55）

Normal and pathological states generated by dynamical properties of the retinal circuit
Katsunori Kitano
Dept. of Information Science and Engineering, Ritsumeikan Univ.

3S06a-5（16:05）

Rapid and coordinated processing of global motion images by local clusters of retinal ganglion cells
Masao Tachibana1,4，Akihiro Matsumoto2,3,4
Research Organization of Science and Technology, Ritsumeikan Univ, Shiga, Japan
Global Innovation Research Organization, Ritsumeikan Univ, Shiga, Japan3
DANDRITE, Dep Biomedicine, Aarhus Univ, Aarhus, Denmark
4
Dept. Psychol, Grad Sch Hum and Soc, Univ of Tokyo, Tokyo, Japan
1
2

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NEURO2019

Symposium 3S01e

Brain-gut axis: the cutting edge

16:30-18:30

Room 1 (4F International Conference Room)

Chairpersons：Elsevier/NSR Symposium

Takefumi Kikusui ‌Azabu University
Shelly A. Buffington ‌Baylor College of Medicine

Introduction Takefumi Kikusui
Azabu University（16:30）3S01e-1（16:40）Host-microbe interactions regulating synaptic plasticity and behavior
Shelly A Buffington1,2,3
Department of Neuroscience, Cell Biology, & Anatomy, University of Texas Medical Branch, Galveston, TX, USA
Recent Affiliation: Department of Neuroscience, Baylor College of Medicine, Houston, TX, USA
3
Recent Affiliation: Memory and Brain Research Center, Baylor College of Medicine, Houston, TX, USA
12

3S01e-2（17:05）PSYCHONEUROIMMUNOLOGY AND GUT MICROBESPaul Forsythe
McMaster University

Symposium
July 27

3S01e-3（17:30）

Gut microbiota and the pathogenesis of multiple sclerosis
Takashi Yamamura
Depat Immunol, National Institute of Neuroscience, NCNP

3S01e-4（17:55）

Gut Microbiota and Brain-Gut Interactions in Irritable Bowel Syndrome
Shin Fukudo
Department of Behavioral Medicine, Tohoku University Graduate School of Medicine

Symposium 3S02e

16:30-18:30

Room 2 (2F Main HallA)

New understanding of functions of basal ganglia in health and disease
Chairpersons：

3S02e-1（16:30）Toshikuni Sasaoka ‌Center for Bioresource-based Researches, Brain Research Institute, Niigata University
Atsushi Nambu ‌National Institute for Physiological Sciences, National Institutes for Natural Sciences

The striatal function in the rhythmical stepping of mice
Takashi Kitsukawa
Graduate school of frontier biosciences, Osaka University

3S02e-2（16:54）

Abnormal information processing through the cortico-basal ganglia pathways is responsible forparkinsonian symptoms
Satomi Chiken1,2，Atsushi Nambu1,2
Div System Neurophysiol, Natl Inst Physiological Sci, Okazaki, Japan1

3S02e-3（17:18）

Dept Physiol Sci, SOKENDAI, Okazaki, Japan

2

Chemogenetic and pharmacological deconstruction of hypokinesia and dyskinesia in Parkinson
modelsM. Angela Cenci Nilsson
Dept. Experimental Medical Science, Lund University, Lund, Sweden

3S02e-4（17:42）Morphological backgrounds of levodopa-induced dyskinesias
Masahiko Tomiyama
Dept Neurol, Hirosaki Univ, Hirosaki, Japan

3S02e-5（18:06）

Mutations in CalDAG-GEFI lead to motor and psychomotor symptoms in multiple species including
human.
Ann M. Graybiel
McGovern Institute for Brain Research, Massachusetts Institute of Technology (MIT)127

Symposium 3S03e

16:30-18:30

The neurobiology of dynamic innate social behaviors
Chairpersons：Room 3 (2F Main HallB)

Takashi Yamaguchi New York University Neuroscience Institute
Aki Takahashi ‌Laboratory of Behavioral Neuroendocrinology, University of Tsukuba

Introduction Interplay between immune system and aggressive behavior（16:30）Takashi Yamaguchi
Neurosci Inst, New York Univ. Sch. of Medicine, New York, USA

3S03e-1（16:34）

Dichotomic control of limbic-hypothalamic linkages for innate social behaviors
Takashi Yamaguchi，Dayu Lin
Neurosci Inst, New York Univ. Sch. of Medicine, New York, USA

3S03e-2（17:03）

Interplay between immune system and aggressive behavior
Aki Takahashi
Laboratory of Behavioral Neuroendocrinology, University of Tsukuba, Japan

3S03e-3（17:32）

Hypothalamic control of aggressive motivation and action
Annegret L Falkner
Princeton Neuroscience Institute, Princeton University

3S03e-4（18:01）

Behavioral examination framework for parental behavior components in rodents, non-humanprimates and humans
Kumi O. Kuroda
Lab for Affiliative Social Behavior, RIKEN Center for Brain Science, Saitama, Japan

Symposium 3S04e

16:30-18:30

Super crosstalk of metabolism and information processing
Chairpersons：

3S04e-1（16:30）

Room 4 (3F 301)

Ko Matsui ‌Tohoku University
Kenji F. Tanaka ‌Keio University

Astrocytic control of neuronal information processing and disease
Ko Matsui
Super-network Brain Physiology, Grad Sch of Life Sci, Tohoku Univ, Miyagi, Japan

3S04e-2（16:50）

The role of innate immunity and lipid metabolism in ischemic stroke
Takashi Shichita
Stroke Rennaisance Project, Tokyo Metro Inst Med Sci, Tokyo, Japan

3S04e-3（17:10）In vivo optical recording reveal state-dependent intracellular ATP dynamics in neurons
Akiyo Natsubori
Sleep Disorders Proj, Tokyo Metropolitan Institute of Medical Science, Tokyo, Japan

3S04e-4（17:30）Regional blood flow regulation by optogenetics
Kenji Tanaka
Dept. Neuropsychiat, Keio Univ Sch of Med, Tokyo, Japan

3S04e-5（17:50）

Dynamics of energy metabolites in brain cells.
Johannes Hirrlinger1,2，Andrea Trevisiol2，Ulrike Winkler1，Susanne Kohler1
University of Leipzig, Carl-Ludwig-Institute for Physiology
Max-Planck-Institute for Experimental Medicine, Dept. of Neurogenetics

1
2

128

NEURO2019

Symposium 3S05e

16:30-18:30

Room 5 (3F 302)

Interpretation of human brain mechanisms and drug discovery using leadingedge stem cell technologies
Chairpersons：

3S05e-1（16:30）Mitsuru Ishikawa ‌Dept. Physiology, Keio University School of Medicine
Yu-Wen Alvin Huang ‌Stanford University Scholl of Medicine

ApoE2, E3 and E4 differentially activate MAP-kinase signaling to regulate amyloid-β secretion andsynapse formation paralleling their role in Alzheimer's disease
Yu-Wen Alvin Huang
Stanford University School of Medicine

3S05e-2（16:55）

Staged Dysregulation of Cortical Development Underlies Psychoses
Tomoyo Sawada1,2,3，Thomas E Chater4，Yohei Sasagawa5，Mika Yoshimura5，Noriko Fujimori3，
Kaori Tanaka5，Yukiko Goda4，Itoshi Nikaido5,6，Tadafumi Kato3
Lieber Inst. for Brain Development, Baltimore, USA 2Dept Neurology, Johns Hopkins Univ Sch of Med, Balrimore, USA
Lab for Mol Dynamics of Mental Dis, RIKEN CBS, Saitama, Japan4
Lab for Synaptic Plasticity and Connectivity, RIKEN CBS, Saitama, Japan5
Lab for Bioinformatics Res, RIKEN BDR, Saitama, Japan6
Sch of Integrative and Global Majors, Univ of Tsukuba, Ibaraki, Japan
1
3

Detecting somatic variations in human brain cells at single cell level
Miki Bundo1,2，Tadafumi Kato3，Kazuya Iwamoto1
Dept. Mol Brain, Kumamoto Univ, Kumamoto

1

3S05e-4（17:45）

Symposium
July 27

3S05e-3（17:20）PRESTO JST

2Lab. for Mol. Dynamics of Mental Disorders, RIKEN CBS

3

Why do we need translational research of psychiatric disorders using human directly induced
neuronal (iN) cells?
Noriaki Sagata，Takahiro A Kato
Dept Neuropsych, Kyushu Univ, Fukuoka, Japan

3S05e-5（18:10）

Cellular Modeling of a Neurodevelopmental Disorder using Functionally Matured Human Excitatory /Inhibitory Neurons
Mitsuru Ishikawa，Hideyuki Okano
Dept Physiol, Keio Univ Sch Med, Tokyo, Japan

Symposium 3S06e

16:30-18:30

Room 6 (2F 201A)

Technological advances of ultra-high field MRI in Neuroscience and the future
direction of laminar/columnar functional MRI
Chairpersons：

Jiajia Yang ‌Graduate School of Interdisciplinary Science and Engineering in Health Systems, Okayama
University, Japan

Laurentius Huber ‌Section on Functional Imaging Methods, National Institute of Mental Health, USA
Introduction Jiajia Yang
Graduate School of Interdisciplinary Science and Engineering in Health Systems, Okayama University, Japan（16:30）3S06e-1（16:36）

Brain microstructure and function using ultra high field MRI
Masaki Fukunaga1,2
Div. of Cerebral Integration, National Inst. for Physiological Sciences, JAPANSchool for Life science, SOKENDAI (The Graduate University for Advanced Studies), JAPAN12

3S06e-2（17:02）

Challenges and opportunities for laminar imaging using Gradient-echo BOLD signal
Kamil Uludag1,2
Koerner Scientist in MR Imaging, Department of Medical Biohysics, University of Toronto
Sungkyunkwan University, Department of Biomedical Engineering and Institute for Basic Science (IBS), Seobu-ro 2066,
Jangan-gu, Suwon, Korea
1
2

129

3S06e-3（17:28）High-field high-resolution fMRI technology reveals information flow across cortical microcircuits oflayers and columns.
Laurentius Huber1,2
University of Maastricht, Maastricht, Netherlands

1

3S06e-4（17:54）

SFIM, LBC, NIMH, NIH

2

Understanding tactile processing at columnar and laminar level using high-resolution fMRI
Yinghua Yu1,2,3，Laurentius Huber3,4，Jiajia Yang1,3，Peter A Bandettini3
Okayama University, Okayama, Japan 2JSPS, Tokyo, Japan
University of Maastricht, Maastricht, Netherlands

1
4Discussion（18:20）130SFIM, LBC, NIMH, NIH, Bethesda, MD, USA

3

NEURO2019

Symposium

Day 4 - July 28

Symposium 4S01m

Prodromal PD -bench to bedside-

8:45-10:45

Room 1 (4F International Conference Room)

Basic and Clinical Neuroscience Collaboration Symposium

Chairpersons：

4S01m-1（8:50）

Ryosuke Takahashi ‌Department of Neurology, Kyoto University Graduate School of Medicine
Noriko Nisihikawa ‌Department of Neurology, National Center for Neurology and Psychiatry Hospital

JPPMI- A cohort study of prodromal PD in Japan
Noriko Nishikawa
National Center for Neurology and Psychiatry

4S01m-2（9:15）

Progression of alpha-synuclein pathology in Parkinson disease
Koichi Wakabayashi
Dept Neuropathol, Hirosaki Univ Sch of Med, Aomori, Japan

4S01m-3（9:40）

Animal model of prodromal Parkinson's disease
Hodaka Yamakado
Dept. of Neurology, Grad. Sch. of Medicine Kyoto Univ.,

4S01m-4（10:05）Extracellular α -synuclein levels are regulated by neuronal activity
Kaoru Yamada，Takeshi Iwatsubo
Dept. of Neuropathology, Graduate School of Medicine, The University of Tokyo

8:45-10:45

Room 2 (2F Main HallA)

Breakthrough that links basic neuroscience and potential therapeuticstrategies for neuropsychiatric disorders
Chairpersons：

4S02m-1（8:45）

Shigeki Moriguchi ‌Dept.of Pharmacol., Grad. Sch. Pharmaceut. Sci., Tohoku Univ.
Akiko Hayashi-Takagi ‌Lab. of Med Neurosci, IMCR, Gunma Univ

Exploration of novel mechanism target for behavioral and psychological symptoms of Alzheimer's
diseaseShigeki Moriguchi，Kohji Fukunaga
Dept Pharmacol, Grad Sch Pharmaceut Sci, Tohoku Univ

4S02m-2（9:15）

Synaptic Plasticity: from bench to bedide
Takuya Takahashi
Dept. of Physiology,Graduate School of Medicine,Yokohama City University, Japan

4S02m-3（9:45）

To make or not to make synapses - possible therapeutic tools for synaptopathies
Michisuke Yuzaki
Dept Physiol, Keio Univ Sch of Med, Tokyo, Japan

4S02m-4（10:15）Cell-based and high content screening of synapse imaging for drug development of psychiatricdisorders
Akiko Hayashi-Takagi
RIKEN, CBS, Lab for Multi-scale Biological Psychiatry131

Symposium
July 28

Symposium 4S02m

Symposium 4S03m

8:45-10:45

Room 3 (2F Main HallB)

New insights on the cortico-hippocampal dialogue underlying memory
Chairpersons：

4S03m-1（8:45）

Thomas John McHugh ‌RIKEN Center for Brain Science
Albert Tsao ‌Stanford University

Episodic time coding in lateral entorhinal cortex
Albert Tsao
Stanford University

4S03m-2（9:09）

Prefrontal top-down control over memory encoding in the hippocampus
Kaori Takehara-Nishiuchi
Univ of Toronto

4S03m-3（9:33）

Disruption of oligodendrogenesis impairs spatial memory consolidation in adult mice
Paul Frankland
Neuroscience & Mental Health, Hospital for Sick Children

4S03m-4（9:57）

Prefrontal cortical neurons reflect hippocampal non-local trajectory information during
hippocampal replay and during theta sequences
David Foster1，Alice Berners-Lee1,2，Xiaojing Wu2
University of California, Berkeley

1

4S03m-5（10:21）2

Dept of Neuroscience, Johns Hopkins University School of Medicine, Baltimore MD, USA

Physiological signature of memory age in the prefrontal-hippocampal circuit
Thomas J. Mchugh
RIKEN Center for Brain Science, Lab for Circuit and Behavioral Physiology

Symposium 4S04m

8:45-10:45

Room 4 (3F 301)

Compartmentalized dendritic integration: from molecular mechanisms tobehavior
Chairpersons：

Naoya Takahashi ‌Humboldt University of Berlin, Institute for Biology
Keisuke Yonehara ‌DANDRITE, Aarhus University

Introduciton Naoya Takahashi ，Keisuke Yonehara
1Institute for Biology, Humboldt University of Berlin, Berlin, Germany（8:45）
2
1

2

DANDRITE, Dept Biomed, Aarhus University, Aarhus, Denmark

4S04m-1（8:48）

Differential pre and postsynaptic contributions in setting the synaptic strengths across a dendritic
tree in hippocampal neurons
Yukiko Goda1，Mathieu Letellier2
RIKEN Center for Brain Science1

4S04m-2（9:15）

Institut Interdisciplinaire de Neurosciences, UMR5297, Bordeaux, FRANCE

2

Dendritic compartment-specific regulation of spine density during development
Takeshi Imai
Grad Sch of Med Sci, Kyushu Univ, Fukuoka, Japan

4S04m-3（9:35）

Spatiotemporally asymmetric excitations support retinal motion sensitivity
Keisuke Yonehara1，Akihiro Matsumoto1，Kevin Briggman2
DANDRITE, Dept Biomed, Aarhus University, Aarhus, Denmark
Center of Advanced European Studies and Research (caesar), Bonn, Germany

1
2

4S04m-4（9:55）

Subclass-specific dendritic activation of cortical pyramidal neurons gates tactile perception in mice
Naoya Takahashi，Matthew Larkum
Institute for Biology, Humboldt University of Berlin, Berlin, Germany132

NEURO2019

4S04m-5（10:15）

Learning and sleep-dependent branch-specific dendritic spine plasticity in the cortex
Wenbiao Gan1，Zhiwei Xu1，Yanmei Zhou1,3，Cora Lai2，Guang Yang3
New York University School of Medicine
School of Biomedical Sciences, Li Ka Shing Faculty of Medicine, University of Hong Kong
3
Department of Anesthesiology, Columbia University Medical School
1
2

Discussion（10:42）
Symposium 4S05m

8:45-10:45

Cortical circuit development:role of thalamocortical input
Chairpersons：

4S05m-1（8:45）Tomomi Shimogori ‌RIKEN Center for Brain Science
James Andrew Bourne ‌Australian Regenerative Medicine Institute, Monash University, Australia

Development and function of Phox2a+ spinofugal nociceptive projection neurons
Artur Kania1,2，Brian R. Roome1,2，Shima Rastegar-Pouyani1,2，Susana Sotocinal2，Annie Dumouchel1，
W. Scott Thompson1，Jean-Francois Brunet3，Marie Kmita1，Jeff Mogil2
Institut de Recherches Cliniques de Montreal (IRCM), Montreal, Canada
Ecole Normale Superieure, Paris, France

1
3

4S05m-2（9:15）

Room 5 (3F 302)

McGill University, Montreal, Canada

2

Organization of mouse dLGN: circuits underlying a faithful relay and active filtering of retinal signaling
to visual cortex.
William Guido
Anatomical Sciences and Neurobiology, University of Louisville, KY, USA

Symposium
July 28

4S05m-3（9:45）

The control of Post-mitotic Neuronal Development by pre-synaptic Thalamocortical inputs
Tomomi Shimogori，Timothy R Young
RIKEN CBS

4S05m-4（10:15）Development of pulvino-cortical circuits: implications for behaviours and disorders.
James Andrew Bourne
Australian Regenerative Medicine Institute, Monash University, Australia

Symposium 4S06m

8:45-10:45

Room 6 (2F 201A)

Dynamics and its novel mechanisms of "capillary-milieu" in the CNS
development and diseases
Chairpersons：Ken-ichi Mizutani ‌Graduate School of Pharmaceutical Sciences, Kobe Gakuin University
Nozomu Takata ‌Center for Vascular and Developmental Biology, Feinberg School of Medicine,Northwestern University

Introduction Ken-ichi Mizutani
Grad Sch Pharm Sci, Kobe Gakuin Univ
（8:45）
4S06m-1（8:50）

Interaction of neurogenesis and angiogenesis is essential for the proper assembly of the neocortex
Ken-ichi Mizutani
Grad Sch Pharm Sci, Kobe Gakuin Univ

4S06m-2（9:12）

Visualization of vascular dynamics using artificial microvessel model
Yukiko Matsunaga
Inst. Indust Sci, Univ of Tokyo, Tokyo

133

4S06m-3（9:34）

Molecular identification and cell-type specific signatures during eye organoid morphogenesis
Nozomu Takata1，Fiore Luciano1，He Liqun2，Marc A. Morgan3，Manuel JG. Rodriguez4，Nikita Joshi5，
Alexander V. Misharin5，Ryan B. Embry6，Priyam Patel6，Matthew Schipma6，Ali Shilatifard3，
Christer Betsholtz2，Guillermo Oliver1
Center for Vascular and Developmental Biology, Feinberg Cardiovascular and Renal Research, Feinberg School of Medicine,Northwestern Univ, Chicago, USA
2
Dept Immunology, Genetics and Pathology, Rudbeck Lab, Uppsala Univ, Uppsala, Sweden.
3
Dept Biochemistry and Molecular Genetics, Northwestern Univ, Feinberg School of Medicine, Chicago, USA
4
Spanish National Center for Cardiovascular research, Madrid, Spain
5
Dept Med and Pulmonary and Critical Care Medicine, Northwestern Univ, Chicago, USA.
6
Feinberg Cardiovascular and Renal Research Institute, Feinberg School of Medicine, Northwestern Univ, Chicago, USA
1

4S06m-4（9:56）

Neural retina-derived retinoic acids controls choroidal vasculature development
Akishi Onishi1,2Lab. for Retinal Regeneration, RIKEN BDR
Patients' iPS Cell Research Unit, Kobe City Eye Hospital Research Center

1
2

4S06m-5（10:18）

Molecular technology regulating the vascular environment for injured brain regeneration
Itsuki Ajioka
Center for Brain Integration Research, Tokyo Medical and Dental Univ.

Discussion（10:40）Nozomu Takata
Inst. Indust Sci, Univ of Tokyo, Tokyo

Symposium 4S07m

8:45-10:45

Room 7 (2F 201B)

New tools for neuroscience research - from nano to macroscales
Chairpersons：

4S07m-1（8:45）

Takayasu Mikuni ‌Brain Research Institute, Niigata University
Kazuki Tainaka ‌Brain Research Institute, Niigata University

Development and application of genome editing technologies in the mammalian brain in vivo
Takayasu Mikuni1,2Dept. Cell Pathol, Brain Research Institute, Niigata Univ, Niigata, Japan
Japan Science and Technology Agency, PRESTO, Saitama, Japan1
2

4S07m-2（9:15）

Correlated Light-Serial Scanning Electron Microscopy (CoLSSEM) for ultrastructural visualization of
single neurons in vivo
Yusuke Hirabayashi1,2,3，Juan Carlos Tapia3，Polleux Franck3
Dept. Chem. and Biotech., School of Eng., Univ. of Tokyo, Tokyo, Japan
Dept. Neurosci. Columbia University, NY, USA

1
3

4S07m-3（9:45）PRESTO JST

2

Dissecting behaviorally-relevant circuits at cellular resolution
Hyungbae Kwon
Max Planck Florida Institute

4S07m-4（10:15）Comprehensive 3D imaging by tissue clearing technique CUBIC
Kazuki Tainaka
Dept Sys Pathol, Niigata Univ, Niigata, Japan134

NEURO2019

Symposium 4S02a

10:50-12:50

Room 2 (2F Main HallA)

Failure of organelle communications as a key pathomechanism forneurological disorders
Sponsored by IBRO-APRC Lecturer Exchange Program
Chairpersons：Kazunori Imaizumi ‌Department of Biochemistry, Institute of Biomedical & Health Sciences, Hiroshima
University

Koji Yamanaka ‌Department of Neuroscience and Pathobiology, Research Institute of Environmental
Medicine, Nagoya University

4S02a-1（10:50）A role of mitochondria-associated membrane in motor neuron degeneration
Koji Yamanaka
Dept. Neuroscience and Pathobiology, Res. Ins. Env. Med. Nagoya Univ, Nagoya, Japan

4S02a-2（11:10）Parkinson's disease seen from a viewpoint of mitochondria-lysosome communication
Noriyuki Matsuda
Tokyo Metro. Inst. of Med. Sci.

4S02a-3（11:30）Membrane trafficking: A new frontier in Parkinson's disease
Takafumi Hasegawa
Dept Neurol, Tohoku Univ Grad Sch of Med

4S02a-4（11:50）Traffic jam hypothesis: endocytic disturbance and Alzheimer's disease pathology
Nobuyuki Kimura

4S02a-5（12:10）

Cross-talk between the endoplasmic reticulum and the plasma membrane mediated by the extended
synaptotagmins.
Yasunori Saheki1,2
Lee Kong Chian School of Medicine, Nanyang Technological University, SIngapore
Institute of Resource Development and Analysis, Kumamoto University, Kumamoto, Japan1
2

4S02a-6（12:30）Recovery of lysosomal functions by the shutdown of ER-associated degradation and therapy of
Mucopolysaccharidosis
Atsushi Saito1，Yosuke Osaki2,3，Kazunori Imaizumi2
Dept Stress, Inst Biomed Health Sci, Hiroshima Univ, Hiroshima, Japan
Dept Biochem, Inst Biomed Health Sci, Hiroshima Univ, Hiroshima, Japan
3
Dept Nephrol, Hiroshima Univ Hosp, Hiroshima, Japan1
2

Symposium 4S03a

10:50-12:50

Room 3 (2F Main HallB)

Diverse functions of the reward system: from sleep regulation to executivefunction
Chairpersons：

Masayuki Matsumoto ‌University of Tsukuba
Kae Nakamura ‌Kansai Medical University

Introduction Masayuki Matsumoto
University of Tsukuba（10:50）
4S03a-1（10:55）

The role of primate striatum for decision making under different emotional context
Kae Nakamura，Yasumasa Ueda，Masaharu Yasuda
Dept Physiol, Kansai Medical University, Osaka, Japan

4S03a-2（11:18）

Role of the striatal local network in environment-based behavioral switching
Jun Kunimatsu1,2，Okihide Hikosaka2
Faculty of Med, Univ Tsukuba, Tsukuba, Japan

1

National Eye Institute, NIH, MD, U.S.A.

2

135

Symposium
July 28

Sect Cell Biol & Pathol, Dept AD Res, NCGG

4S03a-3（11:41）

Why do we fall asleep when bored - The gating of sleep by motivated behaviors
Michael Lazarus
University of Tsukuba

4S03a-4（12:04）

Why would you want to know? The neuronal mechanisms of uncertainty reduction in primates
Ilya E Monosov
Washington Univerisity in St Louis

4S03a-5（12:27）

Two axes of dopamine evaluation systems: reward and threat
Mitsuko Watabe-Uchida
Harvard University, Cambridge, USA

Symposium 4S04a

10:50-12:50

Room 4 (3F 301)

Innovative researches for drug discovery and development ~ novel
technologies have become clear throughout common functions between
oligodendrocytes and Schwann cells
Chairpersons：

Shingo Miyata ‌Division of Molecular Brain Science, Research Institute of Traditional Asian Medicine,
Kindai University

Tsuyoshi Hattori ‌Department of Neuroanatomy, Kanazawa University Graduate School of Medical
Sciences

4S04a-1（10:50）BIG1/Arfgef1 and Arf1 regulate the initiation of myelination by Schwann cells in mice
Junji Yamauchi1,2，Yuki Miyamoto1,2
Laboratory of Molecular Neuroscience and Neurology,Tokyo University of Pharmacy and Life Sciences
Department of Pharmacology, NICHD (Japan)

1
2

4S04a-2（11:14）

The role of astrocytic CD38 for myelination and demyelination
Tsuyoshi Hattori1，Jureepon Roboon1，Hiroshi Ishii1，Mika Takarada1，Dinh Thi Nguyen1，
Haruhiro Higashida2，Osamu Hori1
Dept. Neuroanatomy, Kanazawa Univ. Grad. Sch. Med. Sci., Kanazawa

1

4S04a-3（11:38）Res. Cent. Child Mental Dev., Kanazawa Univ.

2

Towards understanding of novel molecular mechanisms underlying oligodendrocyte properties bothin normal and pathological condition
Yugo Ishino1，Shoko Shimizu1，Masaya Tohyama1,2，Shingo Miyata1
Div Mol Brain Sci, Res Inst Trad Asian Med, Kindai Univ, Osaka, Japan1

4S04a-4（12:02）

Osaka Pref Hosp Org, Osaka, Japan

2

Axon initial segment: a key structure for CNS pathophysiology
Keiichiro Susuki
Dept Neurosci, Cell Biol&Physiol, Wright State Univ, Dayton, USA

4S04a-5（12:26）Large-scale volume imaging of the myelinated nerve fibers with electron microscopy
Nobuhiko Ohno1,2，Tatsuhide Tanaka3
Dept Anat, Jichi Med Univ, Tochigi, Japan 2Div Neurobiol Bioinformatics, Nat Inst Physiol Sci, Aichi, Japan
Dept Anat Neurosci, Nara Med Univ, Nara, Japan

1
3

Symposium 4S05a

10:50-12:50

Room 5 (3F 302)

From bench to bedside: Seamless development of therapy for neurologicaldiseases

JSN Symposium

Chairpersons：

4S05a-1（10:50）

Yoshitaka Nagai ‌Osaka University
Sayaka Takemoto-Kimura ‌Department of Neuroscience I, RIEM, Nagoya University

Genetic Diseases Caused by Aberrant Splicing and Their Therapeutics
Masatoshi Hagiwara
Dept. Anatomy and Dev. Biol., Kyoto Univ. Grad. Sch. of Med.

136

NEURO2019

4S05a-2（11:20）Antisense correction of SMN2 splicing rescues SMA
Kentaro Sahashi
Dept. Neurology, Nagoya Univ, Nagoya, Japan

4S05a-3（11:50）

Towards a systematic understanding and treatment of the sugar chain synthesis disorders, including
Fukuyama muscular dystrophy, and Parkinson's disease
Tatsushi Toda
Department of Neurology, Graduate School of Medicine, The University of Tokyo

4S05a-4（12:20）Development of therapeutic strategies to repair neuronal network for the central nervous systemdiseases
Toshihide Yamashita
Dept. Mol Neurosci, Osaka Univ, Osaka, Japan

Symposium 4S06a

10:50-12:50

Room 6 (2F 201A)

The Confluence of Multi-modal/Multi-scale Imaging and Brain Science
Chairpersons：

Yasuyoshi Watanabe ‌RIKEN Compass to Healthy Life Research Complex Program
Yosky Kataoka ‌RIKEN Center for Biosystems Dynamics Research

Introduction Yasuyoshi Watanabe
RIKEN RCH+BDR（10:50）Multi-scale, multi-modal in-vivo imaging of neurodegeneration
Makoto Higuchi

Symposium
July 28

4S06a-1（10:55）Nat Inst of Quantum and Radiol Sci and Technol

4S06a-2（11:25）Multi-modal imaging of glial progenitor cells
Yosuke Kataoka1，Yasuhisa Tamura1,2，Satoshi Kume1,2，Mitsuyo Maeda1,2，Asami Eguchi1,2，
Mitsuo Suga2
Lab. for Cellular Function Imaging, RIKEN BDR, Hyogo, Japan
Multi-Modal Microstructure Analysis Unit, RIKEN-JEOL Collaboration Center, Hyogo, Japan1
2

4S06a-3（11:55）

Translational PET Neuroimaging
Christer Halldin
Karolinska Institute

4S06a-4（12:20）The molecular and neural mechanisms of fatigue and chronic fatigue revealed by integrated multimodal imaging technologies
Yasuyoshi Watanabe
RIKEN RCH+BDR

Symposium 4S07a

10:50-12:50

Room 7 (2F 201B)

Insight about higher brain functions on the cerebro-cerebellar network fromcollaboration between basic science and clinical research
Chairpersons：Takeru Honda ‌Tokyo Metropolitan Institute of Medical Science
Hironori Nakatani ‌Dept Arts and Sciences, The University of Tokyo Cognition and Behavior Joint
Research Lab., RIKEN CBS

Introduciton Takeru Honda
Tokyo Metropolitan Institute of Medical Science（10:50）
4S07a-1（10:55）What are the neurological symptoms of A-T? How can we approach?
Setsuko Hasegawa
Dept Pediatrics and Developmental Biology, Tokyo Med and Dental Univ, Tokyo, Japan

137

4S07a-2（11:15）

Theory for explicit switch of cerebellar tandem internal models
Takeru Honda
Movement Disorders Project, Tokyo Metropolitan Institute of Medical Science

4S07a-3（11:35）The magnocellular red nucleus underlying coordinated limb movement
Tomomichi Oya1，Tomohiko Takei2,3，Kazuhiko Seki1
Dept. of Neurophysiology , National Inst. of Neuroscience, National Center of Neurology and Psychiatry
Dept. of Physiology & Neurobiology, Graduate School of Medicine, Kyoto University
3
The Hakubi Center for Advanced Research, Kyoto University
1
2

4S07a-4（11:55）

Non-invasive cerebellar stimulation to rearrange disrupted functional networks
Kim van Dun1，Mario Manto2,3
University of Hasselt 2Unite d etude du Mouvement (UEM), FNRS, ULB-Erasme Brussels BelgiumService des Neurosciences, UMons Mons Belgium

1
3

4S07a-5（12:15）

A possible involvement of the cerebellum in expertise in a cognitive domain
Hironori Nakatani1,2
Dept Arts and Sciences, The University of Tokyo

1

Discussion（12:35）

138

Cognition and Behavior Joint Research Lab., RIKEN CBS

2