BIOGENIC AMINES 2005
BIOLOGICAL AND CLINICAL PERSPECTIVESPROGRAM[Thursday, April 28]
Wellcome address
E. Agostinelli (Italy)
R. Ientile (Italy)
Opening lectures
Chairperson: K. Igarashi (Japan), H. M. Wallace (USA)[L 01] P. Coffino (USA)
Designer substrates derived from ornithine decarboxylase test the limits ofproteasome function[L 02] T. Oshima (Japan)
Polyamine biosynthetic pathways in an extreme thermophile, Thermus
thermophilus[L 03] A. Grillo (Italy)
Progress in agmatine research[Friday, April 29]
Session 1 Polyamines and amine oxidases : clinical aspects
Chairpersons: U Bachrach (Israel), E. Agostinelli (Italy)[L 04] U. Bachrach (Israel)
Anticancer activity of amine oxidases microinjected by viruses: a model forgene therapy

[L 05] K. Igarashi (Japan)
Polyamine oxidation and acrolein: novel biochemical markers for diagnosis ofstroke[L 06] E. Agostinelli (Italy)
Thermosensitizing activity of the enzymatic oxidation products of spermine
and in vivo studies suggest a new approach in anticancer therapy[L 07] M. Unzeta (Spain)
Apoptotic effect of plasma semicarbazide sensitive amine oxidase (SSAO) on
vascular cells: its possible implication in neurodegenerative diseases[L 08] D. A. Averill-Bates (Canada)
Mechanisms of apoptosis induced by acrolein, a spermine oxidation product[L 09] M. Marra (Italy)
Bovine serum amine oxidase and spermine potentiate the cytotoxicity inducedon human cancer cells by different anticancer dugs
[L 10] B. Mondovi (Italy)
Connection between amine oxidases and nitric oxide
Oral Presentation for poster [P01-P11]
Chairpersons: A. Toninello (Italy), R. Avola (Italy)
Session 2 Polyamines and transglutaminases
Chairpersons: M. Griffin (UK), V. Gentile (Italy)[L 11] M. Griffin (UK)
Transglutaminase2-induced alterations in the extracellular matrix lead toinhibition of angiogenesis and tumour growth[L 12] V. Gentile (Italy)
Transglutaminases: from the basic biochemistry to the human diseases

[L 13] G. D'Argenio (Italy)
Role of transglutaminases in colon inflammation[L 14] D. Caccamo (Italy)
Transglutaminase and NFkB pathway in inflammatory cells[L 15] A. Campisi (Italy)
Growth factor-neurosteroid cross-talk and transglutaminase in primary
astroglial cell cultures[L 16] G. Li Volti (Italy)
Sigma receptors and tissue transglutaminse in primary rat astroglial cellcultures[Saturday, April 30]
Meetin Italian Biogenic Amines GroupSession 3 Polyamines in cell growth and differentiation
Chairpersons: A. Abbruzzesse (Italy), D. A. Averill-Bates (Canada)[L 17] O. Heby (Sweden)
Polyamine depletion triggers the DNA damage pathway in teratocarcinoma
and embryonic stem (ES) cells[L 18] H. M. Wallace (UK)Polyamine analogues in cancer chemotherapy and prevention[L 19] R. Madhubala (India)
Relationsihp between polyamine biosynthesis and development of antimony
resistance in Leishmania donovani[L 20] K. Kashiwagi (Japan)
Recent progress in polyamine transport systems in Escherichia coli[L 21] A. Facchini (Italy)
Polyamine depletion inhibits apoptosis in huma chondrocytes stimulated byTumor Necrosis Factor-α
Session 4 Polyamines in plants
Chairpersons: O. Heby (Sweden), A. Michael (UK)[L 22] A. Michael (UK)The yeast FMS1 polyamine oxidase is not significantly involved in polyamine
retroconversion: transcriptome and proteome analysis of the effects ofpolyamine acetylation in yeast[L 23] D. Serafini (Italy)
Do polyamines inhibit or stimulate PCD?
[L 24] N. Bagni (Italy)
Effect of different analogues of agmatine on cell proliferation of Helianthus
tuberosus tuber explants
Concluding remarks
Chairperson: E. Agostinelli (Italy), U. Bachrach (Israel)