POLYAMINES 2000
BIOLOGICAL AND CLINICAL PERSPECTIVES
2ND EUROPIAN POLYAMINE CONFERENCE★
Oral Poster Presentations
Chairman: L. Persson (Sweden)[OP 1.7] S. M. Oredsson, K. Alm, P. S. H. Berntsson, J. O. Fredlund, D. L.
Kramer, C. W. Porter (Sweden/USA):
Early consequences on cell cycle progression by polyamine biosynthesis
inhibition.
[OP 1.8] D. A. Johnson, A. Fallon, C. Fields, M. J. Viar, L. R. Johnson(USA):
Effect of polyamine depletion on migration of retinal pigmented epithelialcells.
[OP 1.9] J. Nilsson, A. Gritli-Linde, O. Heby (Sweden):
Skin fibroblasts from spermine synthase-deficient hemizygous gyro mice
overproduce spermidine and exhibit increased resistance to oxidative stress
but decreased resistance to UV irradiation.
[OP 1.10] F. Marini, L. Betti, S. Scaramagli, S. Biondi, P. Torrigiani (Italy):
Upregulation of polyamine biosynthesis and oxidation during thehypersensitive response to TMV.
[OP 2.7] M. Marra, G. Giuverti, A. M. D'Alessandro, S. Beninati, A. Budillon,M. Caraglia, A. Abbruzzese (Italy):Hypusine biosynthesis as a molecular target for the potentiation of apoptosis
in anti-cancer therapy.
[OP 2.8] A. Toninello, E. Pezzato, L. Bordin, G. Clari (Italy):
Energy dependent spermine transport in heart mitochondria and its effect onpyruvate dehydrogenase complex.
[OP 3.13] I. Yoshida, Y. Tarui, E. Hirasawa (Japan):
Photoinduction of key enzymes for polyamine biosynthesis in leaves andflower-bud induction of Pharbitis nil.
[OP 3.14] M. Mayer, A. J. Michael (UK):
Manipulation of ornithine decarboxylase activity in transgenic tobacco.
[OP 3.15] O. Levillain (France):
Renal arginase AII is not involved in polyamine synthesis in the kidney offemale OF-1 mouse.
[OP 3.16] C. Cabella, G. Gardini, D. Corpillo, G. Testore, S. P. Solinas, M. A.
Grillo, S. Colombatto (Italy):
Synthesis of polyamines and GABA from agmatine taken up by rat
hepatocytes.
[OP 5.6] M. Friggeri, N. Tazzini, F. Bacciottini, A. Bonetti, L. Lanati, M.
Manara, A. Luccini, R. Delsignore, A. Casti (Italy):Pattern of blood oxidative state and polyamine concentration in young
athletes.
[OP 6.7] A. Hughes, H. M. Wallace (UK):
Modulation of intracellular polyamine concentrations decreases non-steroidal
anti-inflammatory drug induced cytotoxicity.
[OP 6.8] V. Milovic, J. Stein, G. M. Murphy (Germany/Russia):
Bile acids and colon cancer: are polyamines the missing link?
★
Poster Presentation
Chairman: E. Agostinelli (Italy)[P 1.11] P. S. H. Berntsson, S. M. Oredsson (Sweden):Cyclin expression during the cell cycle in polyamine-depleted chinese hamster
ovary cells.
[P 1.12] C. Hegardt, G. Andersson, S. M. Oredsson (Sweden):Different roles of spermine in glucocorticoid- and Fas-induced apoptosis.
[P 1.13] R. Ray, M. J. Viar, L. R. Johnson (USA):
Role of polyamines in TNF- induced apoptosis in intestinal epithelial cells(IEC-6).
[P 1.14] A. Dale, S. Ellwood, E. Morlon, A. J. Michael (UK):Smart-screening for plant-derived suppressors of polyamine depletion inyeast.
[P 1.15] M. L. van Buuren, L. Guidi, F. Ghetti, S. Fornale, M. Franceschetti,
G. F. Soldatini, N. Bagni (Italy):
Regulation of polyamine biosynthesis during ozone-induced cell death intobacco.
[P 1.16] J. A. Creus, X. Feixa, J. Barcelo (Spain):
Polyamines and DNA in roots of Zea mays cultivars differing in alminium
tolerance.
[P 1.17] C. Illingworth, A. J. Michael (UK):ODC interacting proteins from Arabidopsis and pea.
[P 1.18] C. Stefanelli, I. Stanic, A. Toninello, M. Zini, F. Bonavita, L.
Zambonin, L. Landi, C. Pignatti, F. Flamigni, C. Clo, C. Guarnieri, C. M.
Caldarera (Italy):
Polyamines induce the release of cytochrome c from heart mitochondria.
[P 1.19] Y. Hanzawa, T. Takahashi, A. J. Michael, D. Burtin, D. Long, M.
Pineiro, G. Coupland, Y. Komada (Japan):
Genetic manipulation of plant morphogenesis by an Arabidopsis spermine
synthase gene.
[P 2.9] C. Clo, C. Pignatti, B. Tantini, M. Fattori, C. Stefanelli, A. Facchini, E.
Giordano, M. Menegazzi, C. M. Caldarera (Italy):
Pathways involved in ODC induction by TNF in cultured cardiomyocytes:
role of NF-kB.
[P 2.10] A. Tassoni, M. Franceschetti, F. Spinelli, N. Bagni (Italy):
Cloning of maize coleoptiles spermidine-binding proteins.
[P 3.17] K. Nishimura, Y. Ohki, T. Fukuchi-Shimogori, K. Saiga, K.
Kashiwagi, K. Igarashi (Japan):
Inhibition of active eIF5A formation by deoxyspergualn.
[P 3.18] L. Turchanowa, V. Milovic, A. R. Khomutov, A. S. Shvetsov, R. M.
Khomutov, J. Stein (Germany/Russia):
Cellular polyamine homeostasis and novel spermine analogue,
11-[(amino)oxy-4,9-diaza-1-aminoundecane].
[P 3.19] A. R. Khomutov, Y. Deryabina, A. Demin, A. Shvetsov, R.
Zvyagilskaya (Russia):

Insufficiently charged polyamine analogues.
[P 3.20] L. Marcocci, Z. G. Milella, S. Nocera, S. Di Giovanni, P. Pietrangeli,
O. Befani, B. Mondovi (Italy):
Considerations on fluorimetric methods for the detection of amine-oxidase
activity.
[P 3.21] S. Nasizadeh, L. Thiman, L. Persson (Sweden):
Rapid turnover of a trypanosomal ornithine decarboxylase.
[P 3.22] K. Takao, E. Lovkvist Wallstrom, L. Persson (Sweden):
Importance of the 3' untranslated reigon of ODC mRNA in the translational
control of the enzyme.
[P 3.23] M. Dudkowska, A. Stachurska, W. Chmurzynska, M.
Manteuffel-Cymborowska, B. Grzelakowska-Sztabert (Poland):Cross-talk between androgen receptor and c-met results in down regulation ofODC gene expression in mouse kindey.
[P 3.24] M. Franceschetti, K. Zuccherelli, M. J. Mayer, A. J. Michael, N.
Bagni (Italy/UK):
Morphological and biochemical analysis of spermidine synthase sense andantisense tobacco plants.
[P 3.25] F. Antognoni, M. Mutuale, N. Bagni (Italy):Bis(guanylhydrazones) inhibit germination of pollen from Actinidiachinensis.
[P 3.26] S. Scaramagli, F. Paglierani, S. Biondi, M. Mayer, A. J. Michael, P.
Torrigiani (Italy/UK):
Altered putrescine-to-spermidine ratios in SAMDC antisense tobacco.
[P 3.27] F. Pieckenstain, A. Garriz, E. Chornomaz, D. Sanchez, O. A.
Ruiz (Argentina):
Inhibition of polyamine biosynthesis in the phytopathogenetic
fungiSclerotinia sclerotiorum.
[P 3.28] L. Bassie, O. Lepri, P. Christou, T. Capell (UK):
Transgenic cell lines as a useful tool to study the biochemistry ofdown-regulation of an endogenous rice gene using a pea diamine oxidase
cDNA.
[P 3.29] C. Hanfrey, A. J. Michael (UK):
Translational regulation of plant S-adenosylmethionine decarboxylase.
[P 3.30] E. Moyano, S. Fornale, A. Mallol, S. Bentebibel, J. Palazon, N. Bagni,
M. T. Pinol (Spain/Italy):Over-expressing putrescine-N-methyltransferase in Datura
metel and Duboisia hybrid hairy root cultures.
[P 3.31] P. Tavladoraki, F. Polticelli, V. Gobbi, L. Ricci, G. Rea, R. Angelini,
R. Federico (Italy):
Heterologous expression and site-directed mutagenesis of maize polyamineoxidase.
[P 4.7] S. Del Duca, L. Dondini, M. Della Mea, D. Serafini-Fracassini (Italy):
Factors affecting transglutaminase in the isolated chloroplast underillumination.
[P 5.7] G. G. Pinna, S. Marchese, C. Carru, G. M. Pes, A. Naitana, M. Cossu,
G. Sorba (Italy):
Erythrocyte polyamine levels in stable renal transplant recipients.
[P 5.8] P. Ruggeri, L. Denaro, I. Venza, A. Valenti, G. Nicocia, D. Teti
(Italy):Polyamine metabolism in PGE2 treated human T lymphocytes from subjects
with gastric tumor.
[P 6.9] J. G. Delcros, B. Martin, S. Tomasi, M. Le Roch, J. Renault, P. Uriac(France):
Probing the structural specificities of the polyamine transport system withnovel polyamine-azepine conjugates.
[P 6.10] S. Pedeboscq, B. L'Azou, S. Frappier, J. Cambar, J. P. Pometan(France):
Determination of polyamine levels on primary glioblastoma cell cultures.
[P 6.11] F. T. A. Beira, M. A. Trejo, I. Claparols, L. Rodriguez, M. P.
Rivera-Fillat, M. R. Grau-Oliete (Spain):
Polyamine biosynthesis inhibition and cytotoxic effect of Jodina rhombifolia
Hook et Arn fractoins in human pancreatic carcinoma cells.
[P 6.12] C. Soede-Huijbregts R. Shipper, P. Verdegem, M. Sedelaar, E.
Humpfer, M. Spraul, J. de la Rosette, J. C. Romijn, A. Verhofstad, A.
Heerschap (Germany/Netherlands):
Polyamines as biomarkers of prostatic cancer diagnosis using 1H-HRMASNMR.
[P 6.13] L. Turchanowa, R. Bauske, V. Milovic, J. Stein (Germany):

Nonsteroidal antiinflammatory drugs down-regulate c-myc and ODC
expression in colon cancer cells.
[P 7.5] A. Sass-Kiss, G. Hajos (Hungary):
Polyamines in hungarian Aszu Wines.
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Concluding Remarks
U. Bachrach (Israel)★