㎰ᯘỈ⏘┬㻌
ᖹᡂ28ᖺᗘ⸆⏝స≀➼ᆅᇦ≉⏘స≀⏘ᆅ☜❧ᨭ᥼஦ᴗ⸆㻌 ⏝㻌 స㻌 ≀㻌㻌 㻌 ᱂ᇵ䛾ᡭᘬ䛝䝖㻌 䜴㻌 䜻㻌 㻌 㻌 䝅䝱䜽䝲䜽㻌䝉䞁䜻䝳䜴㻌 㻌 䝭䝅䝬䝃䜲䝁㻌㻌 㻌 㻌 㻌 䝆㻌 䜸㻌 䜴㻌ᖹᡂ䠎䠕ᖺ䠏᭶⸆⏝స≀⏘ᆅᨭ᥼༠㆟఍⦅㞟༠ຊ㻌 ᅜ❧◊✲㛤Ⓨἲே ་⸆ᇶ┙䞉೺ᗣ䞉ᰤ㣴◊✲ᡤ㻌 㻌 㻌 㻌 㻌 㻌 㻌 㻌 㻌 㻌 ⸆⏝᳜≀㈨※◊✲䝉䞁䝍䞊ࡣࡌࡵ࡟ ₎᪉〇๣࣭⏕⸆ࡢཎᩱ࡜࡞ࡿ⸆⏝స≀ࡣࠊࡑࡢ኱㒊ศࢆ㍺ධࠊ≉࡟୰ᅜ࡟኱ࡁࡃ౫Ꮡࡋ࡚࠸ࡲࡍࠋ㏆ᖺࠊ୰ᅜ࡟࠾ࡅࡿᅜෆ㟂せࡢቑ኱ࡸ㈨※㔞ࡢῶᑡ➼࡟ࡼࡾࠊ㍺ධ౯᱁ࡀᛴ㏿࡟㧗㦐ࡍࡿ࡞࡝ࠊ౪⤥ࡀ୙Ᏻᐃ࡟࡞ࡾࡘࡘ
࠶ࡾࡲࡍࠋ୍᪉࡛ࠊᡃࡀᅜࡢᅜෆ㟂せࡣሀㄪ࡟᥎⛣ࡋ࡚࠾ࡾࠊཎᩱࡢᏳᐃ
౪⤥ࡢࡓࡵ࡟ࡣࠊᅜෆ⏘ᆅࢆ᪩ᛴ࡟⫱ᡂࡋ࡚࠸ࡃ஦ࡀ㔜せ࡜࡞ࡗ࡚࠾ࡾࡲ
ࡍࠋ ࡋ࠿ࡋࠊ⸆⏝స≀᱂ᇵ࡟㛵ࡍࡿ୍⯡ྥࡅࡢ▱ぢࡣᑡ࡞ࡃࠊ⌧ሙ࡛᱂ᇵᣦ
ᑟ࡟࠶ࡓࡿᣦᑟ⪅ࡶᑡ࡞࠸ࡢࡀ⌧≧࡛࠶ࡾࠊ᪂ࡓ࡞స௜ࡅࢆᕼᮃࡍࡿ㎰ᴗ⪅ࡸ⏘ᆅ࠿ࡽࡣࠊ⸆⏝స≀ࡢ᱂ᇵ➼࡟㛵ࡋ࡚ᖖ᫬┦ㄯ࡛ࡁࡿయไᩚഛࡢせᮃࡀ࠶ࡆࡽࢀ࡚࠸ࡲࡋࡓࠋ ⸆⏝స≀⏘ᆅᨭ᥼༠㆟఍ࡣࠊࡇࢀࡽࡢせᮃ࡟ᑐᛂࡋࠊ㎰ᯘỈ⏘┬ࡢ⿵ຓ஦ᴗࠕᖹᡂ  ᖺᗘ⸆⏝స≀⏘ᆅᨭ᥼యไᩚഛ஦ᴗࠖࡢ୍⎔࡜ࡋ࡚ࠕᣦᑟ
⪅⫱ᡂࡢࡓࡵࡢ᱂ᇵᢏ⾡◊ಟ఍ࠖࢆ⾜ࡗ࡚ࡁࡲࡋࡓࠋࡑࡢ୰࡛ࠊࡇࢀ࠿ࡽ
⸆⏝స≀࡟ྲྀࡾ⤌ࡴ᪉ࠎ࠿ࡽࠊ᱂ᇵ࣐ࢽࣗ࢔ࣝ࡟㛵ࡍࡿ㉁ၥࡀከࡃฟࡉࢀ
ࡲࡋࡓࠋࡑࡇ࡛ࠊᅜ❧◊✲㛤Ⓨἲே་⸆ᇶ┙࣭೺ᗣ࣭ᰤ㣴◊✲ᡤ⸆⏝᳜≀㈨※◊✲ࢭࣥࢱ࣮ࡢࡈ༠ຊࡢୗࠊᣢࡕ㐠ࡧࡋࡸࡍࡃࠊ෗┿ࡀ㇏ᐩ࡛ࠊᐇ㝿ࡢ᱂ᇵ⌧ሙ࡟᭷⏝࡜⪃࠼ࡽࢀࡿࠕ⸆⏝స≀᱂ᇵࡢᡭᘬࡁࠖࢆసᡂ࠸ࡓࡋࡲࡋࡓࠋ
ྲྀࡾᢅ࠺ရ┠ࡣࠊᅜෆ࡟࠾࠸࡚ձᐇ㟂࣮࣋ࢫ࡛᱂ᇵࡀྍ⬟࡛࠶ࡾࠊղ౑⏝㔞ࡢከ࠸ရ┠࠿ࡽඃඛⓗ࡟㑅ᢥࡍࡿࡇ࡜࡜ࡋࠊࢺ࢘࢟ࠊࢩࣕࢡࣖࢡࠊࢭࣥ
࢟ࣗ࢘ࠊ࣑ࢩ࣐ࢧ࢖ࢥࠊࢪ࢜࢘࡜ࡋࡲࡋࡓࠋᶆ‽ⓗ࡞᱂ᇵἲࢆグ㍕ࡋ࡚࠸
ࡲࡍࡢ࡛ࠊࡇࢀࢆཧ⪃࡟ࠊᆅᇦࡢẼ㇟᮲௳࡞࡝࡟ᛂࡌ࡚ࡁࡵ⣽ࡸ࠿࡞᱂ᇵ
⟶⌮ࢆࡋ࡚࠸ࡓࡔࡅࢀࡤᖾ࠸࡛ࡍࠋ
ࡇࡢᡭᘬࡁࡀ⸆⏝స≀ࡢ᱂ᇵᣦᑟ⪅ࡢ᪉ࠎࡢ࠾ᙺ࡟❧࡚ࡿࡇ࡜ࢆ㢪ࡗ࡚࠾ࡾࡲࡍࠋ
⸆⏝స≀⏘ᆅᨭ᥼༠㆟఍఍㛗 ᆏ㔝 㞞ᩄ 

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࠙⸆⏝స≀ ᱂ᇵࡢᡭᘬࡁ ⦅㞟ጤဨ఍ࠚ ᕝཎ ಙኵ
㸦ᅜ❧◊✲㛤Ⓨἲே ་⸆ᇶ┙࣭೺ᗣ࣭ᰤ㣴◊✲ᡤ ⸆⏝᳜≀㈨※◊✲ࢭࣥࢱ࣮㛗㸧㣤⏣ ಟ
㸦ᅜ❧◊✲㛤Ⓨἲே ་⸆ᇶ┙࣭೺ᗣ࣭ᰤ㣴◊✲ᡤ ⸆⏝᳜≀㈨※◊✲ࢭࣥࢱ࣮ ⟃Ἴ◊✲㒊㸧ᰘ⏣ ᩄ㑻㸦ᅜ❧◊✲㛤Ⓨἲே ་⸆ᇶ┙࣭೺ᗣ࣭ᰤ㣴◊✲ᡤ ⸆⏝᳜≀㈨※◊✲ࢭࣥࢱ࣮ ᐈဨ◊✲ဨ㸧䕺┠ḟ䕺㻌
㻌⸆⏝స≀䛾᱂ᇵ䛻䛒䛯䛳䛶㻌㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㻌㻝㻌㻌 㻌 ⸆⏝᳜≀䛸୍⯡㎰స≀䛸䛾㐪䛔䛻䛴䛔䛶㻌㻌 㻌 ➨༑୐ᨵṇ᪥ᮏ⸆ᒁ᪉㻌㻌 㻌 ᪥ᮏ⸆ᒁ᪉እ⏕⸆つ᱁㻌 㻞㻜㻝㻡㻌㻌 㻌 䠉᱂ᇵ䛾ᡭᘬ᭩䠉㻌 䛂⸆⏝᳜≀㻌 ᱂ᇵ䛸ရ㉁ホ౯䛃㻌㻌 㻌 ㎰⸆䛾౑⏝䛻䛴䛔䛶㻌㻌㻌䝖䜴䜻᱂ᇵ䛻䛴䛔䛶㻌㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㻌㻣㻌㻌 㻌 䝖䜴䜻䚸䝩䝑䜹䜲䝖䜴䜻㻌㻌 㻌 䝖䜴䜻䠄ᙜᖐ䠅䛾つ᱁㻌㻌 㻌 ⏕⸆䝖䜴䜻䛾ရ㉁㻌
㻌 㻌 ᪥ᮏ䛾ᙜᖐ䛸୰ᅜ䛾ᙜᖐ䚸ཬ䜃㡑ᅜ䛾ᙜᖐ㻌㻌 㻌 䝖䜴䜻䠄䝲䝬䝖䝖䜴䜻䠅䛸䝩䝑䜹䜲䝖䜴䜻䛾ẚ㍑㻌
㻌 㻌 㢮ఝ᳜≀㻌㻌䝖䜴䜻᱂ᇵ䛾ᐇ㝿㻌㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㻌㻝㻣㻌㻌 㻌 䝖䜴䜻᱂ᇵ㐺ᆅ㻌㻌 㻌 䝖䜴䜻᱂ᇵ䛾せⅬ䚸᳜≀䛾≉㉁㻌
㻌 㻌 䝖䜴䜻䛾᱂ᇵᬺ㻌㻌 㻌 䝖䜴䜻䛻㐺⏝䛾䛒䜛㎰⸆౛㻌㻌 㻌 ᪋㻌 ⫧㻌㻌 㻌 ᧛✀䞉⫱ⱑ㻌㻌 㻌 ⱑ䛾᥀ୖ䛢䛸㑅ู㻌㻌 㻌 ⱑ䛾ᐃ᳜㻌㻌 㻌 䠎ᖺ⏕ᰴ䛾⏕⫱㻌㻌 㻌 ཰✭䞉஝⇱㻌㻌 㻌 䝝䝃᥃䛡஝⇱㻌㻌 㻌 ཰✭ᚋ䛾ㄪ〇㻌㻌 㻌 ⣔⤫ಖᏑ䛸᥇✀㻌㻌䝖䜴䜻ཧ⪃㈨ᩱ䠄᱂ᇵヨ㦂䝕䞊䝍䠅㻌㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㻌㻟㻡㻌㻌㻌䝅䝱䜽䝲䜽᱂ᇵ䛻䛴䛔䛶㻌㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㻌㻠㻝㻌㻌 㻌 䝅䝱䜽䝲䜽㻌㻌 㻌 䝅䝱䜽䝲䜽䠄Ⱏ⸆䠅䛾つ᱁㻌㻌 㻌 ⏕⸆䝅䝱䜽䝲䜽䛾ရ㉁㻌
㻌 㻌 ⓑⰟ䚸㉥Ⱏ䚸┿Ⱏ䛻䛴䛔䛶㻌㻌 㻌 ࿴Ⱏ䠄䝽䝅䝱䜽䠅㻌 䛸ὒⰟ䠄䝶䜴䝅䝱䜽䠅㻌 䛻䛴䛔䛶㻌㻌䝅䝱䜽䝲䜽᱂ᇵ䛾ᐇ㝿㻌㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㻌㻠㻥㻌㻌 㻌 䝅䝱䜽䝲䜽᱂ᇵ㐺ᆅ㻌㻌 㻌 䝅䝱䜽䝲䜽᱂ᇵ䛾せⅬ䚸᳜≀䛾≉㉁㻌
㻌 㻌 䝅䝱䜽䝲䜽䛾᱂ᇵᬺ䠄໭ᾏ㐨䠅㻌㻌 㻌 䝅䝱䜽䝲䜽䠄⸆⏝䠅䛻㐺⏝䛾䛒䜛㎰⸆౛㻌㻌 㻌 ᪋㻌 ⫧㻌㻌 㻌 ᳜௜䛡⏝ⱑ䛾సᡂ㻌㻌 㻌 ⱑ䛾᳜௜䛡䛸⩣᫓䛾ⴌⱆ㻌㻌 㻌 ᐃ᳜ᚋ䛾⏕⫱㻌㻌 㻌 ཰㻌 ✭㻌㻌 㻌 ཰✭ᚋ䛾ㄪ〇㻌㻌 㻌 ཧ⪃㈨ᩱ㻌㻌 㻌 䝅䝱䜽䝲䜽䛾⸆⏝ရ✀䛻䛴䛔䛶㻌㻌㻌㻌䝉䞁䜻䝳䜴᱂ᇵ䛻䛴䛔䛶㻌㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㻌㻢㻥㻌㻌 㻌 䝉䞁䜻䝳䜴㻌㻌 㻌 䝉䞁䜻䝳䜴䠄ᕝⰠ䠅䛾つ᱁㻌㻌 㻌 ⏕⸆䝉䞁䜻䝳䜴䛾ရ㉁㻌
㻌 㻌 ᪥ᮏ䛾ᕝⰠ䠄䛫䜣䛝䜕䛖䠅䛸୰ᅜ䛾ᕝⰠ㻔㻯㼔㼡㼍㼚㼤㼕㼛㼚㼓㻕㻌 㻌㻌䝉䞁䜻䝳䜴᱂ᇵ䛾ᐇ㝿㻌㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㻌㻣㻣㻌㻌 㻌 䝉䞁䜻䝳䜴䛾᱂ᇵ㐺ᆅ㻌㻌 㻌 䝉䞁䜻䝳䜴᱂ᇵ䛾せⅬ䚸᳜≀䛾≉㉁㻌
㻌 㻌 䝉䞁䜻䝳䜴䛾᱂ᇵᬺ䠄໭ᾏ㐨䠅㻌㻌 㻌 䝉䞁䜻䝳䜴䛻㐺⏝䛾䛒䜛㎰⸆౛㻌㻌 㻌 ᪋㻌 ⫧㻌㻌 㻌 ✀䜲䝰䛾ᐃ᳜㻌㻌 㻌 䝋䝻䝞䞁᰿䛻䛴䛔䛶㻌㻌 㻌 ᫓䛾ⴌⱆཬ䜃⏕⫱ึᮇ䛾ᵝᏊ䠄໭ᾏ㐨໭㒊䠅㻌㻌 㻌 ⏕⫱୰䡚┒ᮇ䛾ᵝᏊ䠄໭ᾏ㐨໭㒊䠅㻌㻌 㻌 ⏕⫱┒ᮇ䡚⤊ᮇ䛾ᵝᏊ䠄໭ᾏ㐨໭㒊䠅㻌㻌 㻌 ཰㻌 ✭㻌㻌䝉䞁䜻䝳䜴ཧ⪃㈨ᩱ䠄᱂ᇵヨ㦂䝕䞊䝍䠅㻌㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㻌㻥㻝㻌㻌㻌䝭䝅䝬䝃䜲䝁᱂ᇵ䛻䛴䛔䛶㻌㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㻌㻝㻜㻟㻌㻌 㻌 䝭䝅䝬䝃䜲䝁㻌㻌 㻌 䝃䜲䝁䠄ᰘ⬌䠅䛾つ᱁㻌㻌 㻌 ⏕⸆䝃䜲䝁䛾ရ㉁㻌
㻌䝭䝅䝬䝃䜲䝁᱂ᇵ䛾ᐇ㝿㻌㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㻌㻝㻜㻥㻌㻌 㻌 䝭䝅䝬䝃䜲䝁᱂ᇵ㐺ᆅ㻌㻌 㻌 䝭䝅䝬䝃䜲䝁᱂ᇵ䛾せⅬ䚸᳜≀䛾≉㉁㻌
㻌 㻌 䝭䝅䝬䝃䜲䝁䛾᱂ᇵᬺ㻌㻌 㻌 䝭䝅䝬䝃䜲䝁䛻㐺⏝䛾䛒䜛㎰⸆౛㻌㻌 㻌 ✀Ꮚ䞉᧛✀㻌㻌 㻌 ᪋㻌 ⫧㻌㻌 㻌 㛫ᘬ䛝㻌㻌 㻌 㻝ᖺ⏕ᰴ䛾⏕⫱㻌㻌 㻌 ᦬㻌 ⰺ㻌㻌 㻌 ⑓ᐖ⹸㜵㝖㻌㻌 㻌 ཰㻌 ✭㻌㻌 㻌 ᰿䛾ㄪ〇㻌㻌 㻌 ཰㻌 㔞㻌㻌 㻌 ᥇✀䛸✀Ꮚ䛾ㄪ〇㻌㻌㻌䝆䜸䜴᱂ᇵ䛻䛴䛔䛶㻌㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㻌㻝㻞㻡㻌㻌 㻌 䝆䜸䜴㻌㻌 㻌 䝆䜸䜴䠄ᆅ㯤䠅䛾つ᱁㻌㻌 㻌 ⏕⸆䝆䜸䜴䛾ရ㉁㻌
㻌 㻌 ✀㻌 㢮㻌㻌䝆䜸䜴᱂ᇵ䛾ᐇ㝿㻌㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㽂㻌㻝㻟㻟㻌㻌 㻌 䝆䜸䜴᱂ᇵ㐺ᆅ㻌㻌 㻌 䝆䜸䜴᱂ᇵ䛾せⅬ䚸᳜≀䛾≉㉁㻌
㻌 㻌 䝆䜸䜴᱂ᇵᬺ㻌㻌 㻌 ᪋㻌 ⫧㻌㻌 㻌 ⦾Ṫἲ䞉᳜䛘௜䛡㻌㻌 㻌 㧗␇䞉䝬䝹䝏᱂ᇵ㻌㻌 㻌 ⑓ᐖ⹸㻌㻌 㻌 ཰✭䞉཰㔞㻌⸆⏝స≀䛾᱂ᇵ䛻䛒䛯䛳䛶⸆⏝᳜≀䛸୍⯡㎰స≀䛸䛾㐪䛔䛻䛴䛔䛶1䠅୍స䛾᱂ᇵᮇ㛫䛜㛗䛔䜒䛾䛜ከ䛟䚸⏿䛾฼⏝ຠ⋡䛜ᝏ䛔䚹
2䠅ṇ䛧䛔✀㢮䛾✀ⱑ䛾ධᡭඛ䛜㝈䜙䜜䛶䛔䛶䚸ධᡭ䛜㞴䛧㻌 䛔ရ┠䛜ከ䛔䚹
3䠅᱂ᇵရ✀䛜䜋䛸䜣䛹⫱ᡂ䛥䜜䛶䛔䛺䛔䚹
4䠅㎰⸆㢮䛾౑⏝䛜䛛䛺䜚㝈ᐃ䛥䜜䛶䛔䛶䚸㎰⸆䛜౑䛘䛺䛔㻌 ရ┠䛜ከ䛔䚹
5䠅ከ䛟䛾సᴗ䛜ேຊ䞉ᡭసᴗ䛻䜘䜛ሙྜ䛜ከ䛟 䚸ᶵᲔ໬䛜㻌 㐜䜜䛶䛔䜛䚹
6䠅཰✭ᚋ䛻஝⇱䞉ㄪ〇ᕤ⛬䛜ᚲせ䛻䛺䜛䚹7䠅་⸆ရ䛸䛧䛶䛾ရ㉁ᇶ‽䠄᪥ᮏ⸆ᒁ᪉䚸᪥ᮏ⸆ᒁ᪉እ㻌 ⏕⸆つ᱁䠅䜔ᐇ㟂⪅䛾㻌 ရ㉁つ᱁䜢䜽䝸䜰䛩䜛ᚲせ䛜䛒䜛䚹
8䠅㎰స≀䛾䜘䛖䛻ᕷሙ䛜䛺䛟ዎ⣙᱂ᇵ䛜୺ὶ䛷䛒䜚䚸ᐇ㟂㻌 ⪅䛸䛾┤᥋ྲྀᘬ䛸䛺䜛䚹
9䠅་⸆ရཎᩱ䛾ሙྜ䛿䚸ᅜ䛜ᐃ䜑䜛⸆౯䛾⠊ᅖ䛷䛾㈙ྲྀ㻌㻌 䜚䛻䛺䜛䚹㻌㻔ᕷሙཎ⌮䛸䛿↓㛵ಀ䠅䚹㻌─1─䛂➨༑୐ᨵṇ᪥ᮏ⸆ᒁ᪉䛃ⱥㄒྡ䠖䇾The Japanese Pharmacopoeia
17 th edition䇿
(␎ྡ䠖JP17)ᖹᡂ28ᖺ䠏᭶䠓᪥ཌ⏕ປാ┬࿌♧➨64ྕ䛻䛶䚸ཌ⏕ປാ኱⮧䜘䜚➨༑୐ᨵṇ᪥ᮏ⸆
ᒁ᪉䛜බ♧䛥䜜䚸
ᖹᡂ28ᖺ䠐᭶䠍᪥䛛䜙㐺⏝䛥䜜䛶䛔
䜛䚹ཌ⏕ປാ┬་⸆䞉⏕ά⾨⏕ᒁ ᑂᰝ⟶⌮ㄢཬ䜃ᆅ᪉ཌ⏕ᒁ୪䜃䛻㒔㐨ᗓ┴ᗇ䛻ഛ䛘⨨䛛䜜䛶
䛔䜛䚹(ཌ⏕ປാ┬HP䛛䜙
䝎䜴䞁䝻䞊䝗ྍ⬟)─2─䛂᪥ᮏ⸆ᒁ᪉እ⏕⸆つ᱁ 2015䛃㻌 䠄␎ྡ䠖ᒁእ⏕つ 2015䠅ⱥㄒྡ䠖䇾The Japanese standards for㻌 㻌 㻌 㻌 㻌 㻌 㻌 non-Pharmacopoeial crude drugs 2015䇿(␎ྡ䠖䇾non-JP crude drug standards 2015䇿㻌 㻌 㻌 㻌 㻌 㻌 㻌 㻌 㻌 㻌 㻌 㻌 㻌 ཪ䛿䇾Non-JPS 2015䇿)⸆⏕ᑂᰝⓎ1225➨1ྕ䚸ᖹᡂ27ᖺ12᭶25᪥௜䛡䛷ཌ⏕ປാ┬་⒪䞉⏕ά⾨⏕ᒁᑂᰝ⟶⌮ㄢ㛗䛛䜙඲ᅜྛ㒔㐨ᗓ┴⾨⏕୺⟶㒊䠄ᒁ䠅㛗䛒䛶䛻㏻▱
䛥䜜䛯䜒䛾䛷䚸ᖹᡂ28ᖺ䠐᭶䠍᪥䛛䜙᪋⾜䛥䜜䛶䛔䜛䚹(ཌ⏕ປാ┬HP䛛䜙䝎䜴䞁䝻䞊䝗ྍ⬟)

75ရ┠䛾⏕⸆䛾つ᱁䛜グ㍕䛥䜜䛶䛔䜛䚹─3─

-᱂ᇵ䛾ᡭᘬ᭩-Ẑᕤဇౡཋᴾ ఎؔểԼឋᚸ̖ẑᴾᴾ ᴾ
ᕤʙଐ‫إ‬ᅈᴾ ҽဃі΁ႾႳ̲ᴾ

Part 1䠖1992ᖺࠥPart 12䠖2011ᖺྜィ䠒䠏✀㢮䛾⏕⸆䛾᱂ᇵ䞉ㄪ〇ἲ䞉ရ㉁ホ౯ἲ䜢཰㍕䚹
⌧ᅾ⥅⥆䛧䛶సᡂ୰䚹─4─䛂⸆⏝᳜≀㻌㻌 ᱂ᇵ䛸䛸ရ㉁ホ౯䛃 (᱂᱂ᇵᣦ㔪)--Part 1 ࠥ12䛻䛻グ㍕䛥䛥䜜䛶䛔䜛⸆
⸆⏝᳜≀୍୍ぴ--௨ୖ䛾䠒䠏ရ┠Part 3䚸㻌4䚸5 䚸8䛿⌧ᅾ⤯∧䛸䛺䛳䛶䛔䜛䟿㻌─5─

㎰⸆䛾౑⏝䛻䛴䛔䛶኱䜾䝹䞊䝥䛂㔝⳯㢮䛃ศ㢮䛥䜜䜛୺䛺⸆⏝᳜≀
䜰䜿䝡㻌

䜰䝅䝍䝞㻌

䜰䝬䝏䝱㻌

䜰䝬䝗䝁䝻䠄㣗⏝䠅㻌䜰䝻䜶䠄㣗⏝䠅㻌䜲䝏䝵䜴㻌䜴䜲䜻䝵䜴䠄ⴥ䠅㻌

䜴䝁䜼㻌

䜴䝁䞁㻌

䜴䝇䝞䝃䜲䝅䞁㻌

䜶䝡䝇䜾䝃䠄ⱼⴥ䠅㻌

䜸䜴䜼㻌

䜸䜴䝺䞁㻌

䜸䜴䝞䝘䜸䜿䝷㻌

䜸䜿䝷㻌䜹䝜䝁䝋䜴㻌

䜺䝆䝳䝒㻌

䜹䝭䝒䝺㻌

䜹䝽䝷䜿䝒䝯䜲㻌

㣗⏝䜼䜽䠄ⰼ䠅㻌䜽䝁䠄ⴥ䠅㻌

䜽䝽䠄㣗⏝䠅㻌

䝀䞁䝜䝅䝵䜴䝁㻌

䝁䜺䝛䝞䝘㻌

䝁䞁䝣䝸䞊䠄ⴥ䠅㻌䝃䝣䝷䞁㻌䝃䞁䝅䝵䜴䠄ⴥ䠅㻌䝆䜸䜴㻌䝅䝋䠄ⰼ✑䠅㻌

䝅䝱䜽䝲䜽䠄⸆⏝䠅㻌䝅䝵䜴䜺㻌すὒ䝍䞁䝫䝫䠄㣗⏝䠅㻌䝉䝛䜺㻌䝉䞁䜻䝳䜴㻌

䝉䞁䝤䝸㻌

䝎䜲䜸䜴㻌

䝖䜴䜻㻌

䝖䜴䝇䜿䝪䜴䝣䜴㻌䝗䜽䝎䝭㻌䝖䝏䝳䜴䠄ⴥ䠅㻌䝖䝸䜹䝤䝖䠄⸆⏝䠅㻌䝘䜲䝰䜴䜸䜴䜼㻌

䝙䞁䝙䜽㻌

䝝䝑䜹㻌

䝝䝤䝋䜴䠄ⱼⴥ䠅㻌䝝䝬䝪䜴䝣䜴䠄ⴥ䠅㻌䝠䝁䜸䝁䝅㻌

䝧䝙䝞䝘㻌䝩䝋䝞䜸䜿䝷㻌

䝪䝍䞁䝪䜴䝣䜴䠄ⱼⴥ䠅㻌䝭䝅䝬䝃䜲䝁㻌

䝲䝬䝜䜲䝰㻌

⸆⏝䝙䞁䝆䞁㻌

䝴䜻䝜䝅䝍㻌

䝶䝰䜼㻌௨ୗ䛾᳜≀䛿ูศ㢮㻦㻌䜶䝡䝇䜾䝃䠄ᯝᐇ䠅䠙㇋㢮㻔✀ᐇ䠅䚸䝝䝤䝋䜴䠄ᯝᐇ䠅䚸䜴䜲䜻䝵䜴䠄ᯝᐇ䠅㻌䛂ᖹᡂ13ᖺ10᭶10᪥௜䛡13⏕⏘➨3986ྕ㎰ᯘỈ⏘┬⏕⏘ᒁ⏕⏘㈨ᮦㄢ㛗㏻▱䛾ู⾲1䛃䜘䜚䚸ᢤ䛝ฟ䛧䛯୺䛺⸆⏝᳜≀䚹
http://www.acis.famic.go.jp/shinsei/3986/3986beppyou1.pdf

─6─䝖䜴䜻᱂ᇵ䛻䛴䛴䛔䛶䝖䜴䜻䚸䝩䝑䜹䜲䝖䜴䜻㻌㻌⏕⸆ྡ䠖䝖䜴䜻䠄ᙜᖐ䠅㻌ᇶཎ᳜≀䠖䝖䜴䜻㻌Angelica acutiloba Kitagawa 㻔䝉䝸⛉㻕㻌㻌㻌䝩䝑䜹䜲䝖䜴䜻㻌Angelica acutiloba var.sugiyamae Hikino 㻔䝉䝸⛉㻕㻌ཎ⏘ᆅ䠖䛔䛪䜜䜒᪥ᮏ䠄⮬⏕ᆅ䛿ᐃ䛛䛷䛺䛔䠅䚹㻌฼⏝㒊఩䠖᰿䚸᰿ⱼ㻌⸆ຠ䠖ᙉኊ䚸㙠㟼䚸㙠③䚸㈋⾑⑕䚸⭡③䚸⏕⌮୙㡰䚸፬ே䛾᭦ᖺᮇ㞀ᐖ㻌₎᪉ฎ᪉䠖ᙜᖐⰟ⸆ᩓ䚸༑඲኱⿵‫‮‬䚸ຍ࿡㏯㐶ᩓ䛺䛹䚸୍⯡⏝₎᪉〇๣㻞㻥㻠ฎ᪉䛾ෆ䚸㻤㻝ฎ᪉䛻㓄ྜ䚹㻌⏕⏘ᆅ䠖᪥ᮏ䠄ዉⰋ䚸໭ᾏ㐨䚸ᐩᒣ䠅䚸୰ᅜ䠄ᅄᕝ┬䠅㻌 㻌䝖䜴䜻㻌 㻌 㻌䝖䜴䜻⏤᮶䛾⏕⸆䝖䜴䜻䝩䝑䜹䜲䝖䜴䜻
─9─䝩䝑䜹䜲䝖䜴䜻⏤᮶䛾⏕⸆䝖䜴䜻䝖䜴䜻䠄ᙜᖐ䠅䛾つ᱁䠄JP17䠅䝖䜴䜻Japanese Angelica RootANGELICAE ACUTILOBAE RADIXᙜᖐ㻌 ᮏရ䛿䝖䜴䜻Angelica acutiloba Kitagawaཪ䛿 䝩䝑䜹䜲
䝖䜴䜻Angelica acutiloba Kitagawa var. sugiyamae Hikino(Umbelliferae)䛾᰿䜢䠈㏻౛䠈‫‮‬㏻䛧䛧䛯䜒䛾䛷䛒䜛.
⣧ᗘヨ㦂(1) ⴥ䛧䜗䛖 : ⴥ䛧䜗䛖 䜢3.0%௨ୖ䜢ྵ䜎䛺䛔.
(2) 㔜㔠ᒓ䚾1.07䚿* ᮏရ䛾⢊ᮎ3.0 g䜢䛸䜚䠈➨3ἲ䛻䜘䜚᧯స䛧䠈ヨ㦂䜢⾜䛖.ẚ㍑ᾮ䛻䛿㖄ᶆ‽ᾮ3.0mL䜢ຍ䛘䜛 (10 ppm௨ୗ).
(3) 䝠⣲䚾1.11䚿 ᮏရ䛾⢊ᮎ0.40g䜢䛸䜚䠈➨4ἲ䛻䜘䜚᳨ᾮ䜢ㄪ〇䛧䠈ヨ㦂䜢⾜䛖 (5 ppm௨ୗ).
(4) ␗≀䚾5.01䚿 ᮏရ䛿ⴥ䛧䜗䛖௨እ䛾␗≀1.0%௨ୖ䜢ྵ䜎䛺䛔.
⅊ศ䚾5.01䚿 7.0%௨ୗ.
㓟୙⁐ᛶ⅊ศ䚾5.01䚿 1.0%௨ୗ.
䜶䜻䝇ྵ㔞䚾5.01䚿 ᕼ䜶䝍䝜䞊䝹䜶䜻䝇 35.0%௨ୖ.
㈓ἲᐜჾ䠖ᐦ㛢ᐜჾ㻚㻌㻖༑୐ᨵṇ᪥ᮏ⸆ᒁ᪉䛷つᐃ䛥䜜䛶䛔䜛ྛ✀ヨ㦂ἲ䛾᮲㡯␒ྕ䜢♧䛩䚹─ 10 ─

䝖䜴䜻䠄ᙜᖐ䠅䛾つ᱁䠄JP17䠅⏕⸆䛾ᛶ≧㻌㻌 ᮏရ䛿ኴ䛟䛶▷䛔୺᰿䛛䜙ከᩘ䛾᰿䜢ศᯞ䛧䛶䜋䜌⣳㗽ᙧ䜢࿊䛧䠈㛗䛥10 ࠥ25 cm䠈እ㠃䛿ᬯ〓Ⰽ~㉥〓Ⰽ䛷䠈⦪䛨䜟ཬ䜃ᶓ㛗䛻㝯㉳䛧䛯ከᩘ䛾⣽᰿䛾㊧䛜䛒䜛. ᰿㢌䛻ഹ䛛䛻ⴥ䛧䜗䛖䜢ṧ䛧䛶䛔䜛. ᢡ㠃䛿ᬯ〓Ⰽࠥ㯤〓Ⰽ䜢࿊䛧䠈ᖹ䜙䛷䛒䜛.
㻌 ᮏရ䛿≉␗䛺䛻䛚䛔䛜䛒䜚䠈 ࿡䛿ഹ䛛䛻⏑䛟䠈ᚋ䛻䜔䜔㎞ 䛔.
㻌 ᮏရ䛾ᶓษ∦䜢㙾᳨䚾5.01䚿*䛩䜛䛸䛝䠈䝁䝹䜽ᒙ䛿4 ࠥ
10 ᒙ䛛䜙䛺䜚䠈䛭䛾ෆഃ䛻ᩘᒙ䛾ཌゅ⤌⧊䛜䛒䜛. ⓶㒊䛻䛿ศἪ⣽⬊䛻ᅖ䜎䜜䛯ከᩘ䛾Ἔ㐨ཬ䜃䛧䜀䛧䜀኱䛝䛺㝽㛫䛜䛒䜛. ⓶㒊䛸ᮌ㒊䛾ቃ⏺䛿᫂䜙䛛䛷䠈ᮌ㒊䛷䛿ከᩘ䛾㐨⟶䛸ᨺᑕ⤌⧊䛸䛜஺஫䛻ᨺᑕ≧䛻㓄ิ䛧䠈እ᪉䛾㐨⟶䛿༢⊂ཪ䛿ᩘಶ㞟䜎䛳䛶䜔䜔ᐦ䛻㓄ิ䛧䛶䛟䛥䜃≧䜢࿊䛧䠈୰ᚰ㒊௜㏆䛾㐨⟶䛿ᴟ䜑䛶䜎䜀䜙䛻Ꮡᅾ䛩
䜛. 䛷䜣䜇䜣⢏䛿༢⢏ཪ䛿䜎䜜䛻2 ࠥ5ಶ䛾」⢏䛷䠈༢⢏䛾ᚄ䛿20 ʅŵ௨ୗ䠈」⢏䛿25 ʅŵ䛻㐩䛩䜛䛣䛸䛜䛒䜛. 䛷䜣䜇䜣⢏䛿䛧䜀䛧䜀⢶໬䛧䛶䛔䜛.
㻖༑୐ᨵṇ᪥ᮏ⸆ᒁ᪉䛷つᐃ䛥䜜䛶䛔䜛ྛ✀ヨ㦂ἲ䛾᮲㡯␒ྕ䜢♧䛩䚹㻌
─ 11 ─

⏕⸆䝖䜴䜻䛾ရ㉁䘆࿴₎⸆䛾Ⰻྰ㚷ูἲཬㄪ〇᪉䠄୍Ⰽ┤ኴ㑻⦅㻌 ྤ㬅ᇽ᭩ᗑ䠅㻌㻌 䘆⫧䛘䛯኱䛝䛔㨈᰿䛾⃝ᒣ䛴䛔䛶䛒䜛㤿䛾ᑿ䛾䜘䛖䛺᱁ዲ䚹㻌㻌 䘆እ⓶䛜〓⣸Ⰽ䚸ෆ㒊䛜㯤ⓑⰍ䛷䚸࿡䛿ጞ䜑ᑡ䛧⏑䛟䚸ᚋ䛻ᑡ䛧㎞䛟䛶⬟䛝㤶䛸₶䛔䛾䛒䜛䜒䛾䛜䜘䛔䚹㻌䘆⸆⏝᳜≀᱂ᇵ᥇཰ἲ䠄ส⡿㐩ኵ䚸ⱝᯘᴿ
ᅄ㑻ඹⴭ㻌 ༡ᲄ᭩ᗑ䠅㻌 䘆⫧኱䛧₶䛜䛒䛳䛶ᰂ㌾䚸ኴ᰿ከ䛟䚸⏑࿡䛒䜚㤶Ẽ䛾ᙉ䛔䜒䛾䜢Ⰻရ䛸䛩䜛䚹㻌 䘆⪁᰿䛿ṧⱼከ䛟䚸ᮌ໬䛧䛒䜛䛔䛿⬤䛟䛶୙Ⰻ䛷䛒䜛䚹

─ 12 ─᪥ᮏ䛾ᙜᙜᖐ䛸୰ᅜ䛾ᙜᙜᖐ䚸ཬ䜃㡑ᅜ䛾ᙜᖐ䛿ඖ䛻䛺䜛᳜≀䠄ᇶཎ᳜≀䠅䛜䛭䜜䛮䜜␗䛺䜛䟿 ୰ᅜ⏘ᙜᖐ䛾ᇶཎ᳜≀䛿䜹䝷䝖䜴䜻䠄Angelica

sinensis Diels䠅䠖⏑⢔䚸㞼༡䚸ᅄᕝ䚸㝐す䚸㈗ᕞ䚸†໭┬䛺䛹䛻ศᕸ㻌 㻌 㻌 ࿡䛿ᴟ䜑䛶㎞䛔㻌 㡑ᅜ⏘ᙜᖐ䛾ᇶཎ᳜≀䛿䜸䝙䝜䝎䜿䠄Angelica
gigas Nakai䠅䠖㻌 㻌 㻌 ୰ᅜᮾ໭㒊䛛䜙ᮅ㩭༙ᓥ䚸䠄᪥ᮏ䠄஑ᕞ䠅䠛䠅䛻ศᕸ㻌 㻌 㻌 ࿡䛿㎞䛔୰ᅜࡸ㡑ᅜ࡛ࡶᙜᖐࡣ౑ࢃࢀ࡚࠸ࡿࡀࠊ䛣䛾䜘䛖䛻⏕⸆ྡࡣྠ୍࡛࠶ࡗ࡚ࡶ᪥ᮏ࡜୰ᅜࠊ㡑ᅜ࡛ࡣࡑࡢཎ᳜≀ࡀࡑࢀࡒࢀ␗࡞ࡿࡓࡵࠊ᪥ᮏ࡛ࡣ୰ᅜ⏘ཬࡧ㡑ᅜ⏘ᙜᖐࡣ౑࠼࡞࠸ࠋ䝉䞁䜻䝳䜴䛾ሙྜ䛸ྠ䛨䜿䞊䝇䛷䛒䜛䚹 ᚑࡗ࡚ࠊ୰ᅜ࠿ࡽࡢ㍺ධရᙜᖐࡣࠊ᪥ᮏ࠿ࡽ✀Ꮚࡀ୰ᅜ࡟ᣢࡕ㎸ࡲࢀ᱂ᇵࡉࢀࡓࡶࡢ࡛࠶ࡿࠋ

─ 13 ─

䝖䜴䜻䠄䝲䝬䝖䝖䜴䜻䠅䛸䝩䝑䜹䜲䝖䜴䜻䛾ẚ㍑
ⱼⰍ㸸㉥⣸
ⴥᙧ㸸⣽࠸
ⴥⰍ㸸ᬯ⥳Ⰽ
᰿㸸ศᯞ᰿ࡣከࡃ⣽࠸ࠋ  Ⰽࡣ㯤〓Ⰽࠥ㉥〓ⰍࠋⱼⰍ㸸⥳ⴥᙧ㸸ᗈ࠸
ⴥⰍ㸸ῐ⥳Ⰽ
᰿㸸ศᯞ᰿ࡀᑡ࡞ࡃኴ࠸ࠋ  Ⰽࡣῐ࠸㯤〓Ⰽࠋ䝖䜴䜻䠄䝲䝬䝖䝖䜴䜻䠅䝩䝑䜹䜲䝖䜴䜻

䝖䜴䜻䠄䝲䝬䝖䝖䜴䜻䠅䝩䝑䜹䜲䝖䜴䜻
─ 14 ─㻌 㻌 㻌 㻌 㻌 㻌 㻌 㻌 㻌 㢮ఝ᳜≀䠄⏕⸆䝖䜴䜻䛸䛧䛶䛿౑䛘䛺䛔䠅㻌 㻌 㻌 㻌 㻌 㻌 㻌 㻌 㻌 㻌 㻌 㻌 㻌 㻌 䝭䝲䝬䝖䜴䜻㻌Angelica acutiloba Kitagawa var. iwatensis Hikinoศᕸ䠖ᮏᕞ୰㒊௨໭ࠥ໭ᾏ㐨ࢺ࢘࢟ࠊ࣍ࢵ࢝࢖ࢺ࢘࢟࡜ࡶ࡟࣑࣐ࣖࢺ࢘࢟ࡀ᱂ᇵ໬ࡉࢀࡓ
ࡶࡢ࡜࠸࠺ㄝࡶ࠶ࡿࠋ

─ 15 ─

ࢺ࢘࢟᱂ᇵࡢᐇ㝿䝖䜴䜻᱂ᇵ㐺ᆅ䞉Ẽೃ䛿䜔䜔෭ᾴ䛺ᆅᇦ䛻㐺䛩䜛䚹䞉ᅵ㉁䛿⪔ᅵ䛜῝䛟䛶䜔䜔⭾㌾䛺ᇰተᅵ䛜㐺䛧䛶䛔䜛䚹䞉ᆅୗỈ఩䛾㧗䛔䛸䛣䜝䛷䛿䚸༑ศ⏕⫱䛧䛺䛔䛾䛷䚸᤼Ỉ䛾Ⰻ䛔ᅵᆅ䛜ᮃ䜎䛧䛔䚹䞉ⅆᒣ⅊㉁䛾䜘䛖䛺㍍䛔ᅵተ䛷䛿⣽᰿䛜ከ䛟䛺䜚䚸୍᪉䚸⢓ᅵ㉁䛾㔜䛔ᅵተ䛷䛿᰿䛾⏕⫱䛜ຎ䜛䚹䞉཰✭ᚋ䛾ㄪ〇ຍᕤἲ䛾㛵ಀ䛷䚸෤ᮇ䛻ከ㔞䛻㝆㞷䛾䛒䜛ᆅᇦ䛿㐺䛧䛶䛔䛺䛔䚹༶䛱䚸᥀ୖ䛢ᚋ䚸ⱼⴥ௜䛝䞉ᅵ௜䛝䛾䜎䜎䝝䝃᥃䛡䛧䚸
㏻౛䚸᫓ඛ䛻‫‮‬䛻䛴䛡䛶ᅵ䜢Ὑ䛔䚸䛭䛾ᚋ෌䜃䝝䝃᥃䛡䛧䛶᫓䜎䛷஝⇱䛥䛫䜛䛾䛷䚸෤ᮇ䛻ከ㔞䛻㝆㞷䛾䛒䜛ᆅᇦ䛷䛿ᒇእ䛷䛾⮬↛஝⇱䛜ᅔ㞴䛻䛺䜛ࠋࠕ⸆⏝᳜≀ ᱂ᇵ࡜ရ㉁ホ౯ࠖPart 1 (薬事日報社、1992年) 改変

─ 19 ─

䝖䜴䜻᱂ᇵ䛾せⅬ䚸᳜≀䛾≉㉁1䠅⦾Ṫ䛿✀Ꮚ䛻䜘䜛її᫓䛻ⱑᗋ䛻᧛✀䛧䚸䠍ᖺ㛫⫱ᡂ䛧䚸䠎ᖺ┠᫓䛻ⱑ䜢᥀䜚ୖ䛢䛶ᐃ᳜䛩䜛䚹
2䠅᱂ᇵᖺᩘ䛿䠎ᖺїї䠎ᖺ┠䠄ᐃ᳜䛧䛯ᖺ䠅䛾ᬌ⛅䛻཰✭䛩䜛䚹ణ䛧䚸䠎ᖺ┠䛻ᢳⱏ䛧䛯ᰴ䛿ෆ㒊䛜ᮌ㉁໬䛧䛶⏕⸆䛸䛧䛶䛿౑䛘䛺䛔䛾䛷䚸ᢳⱏᰴ䛿◚Რ䛩䜛䚹኱䛝䛺ⱑ䜢᳜䛘䜛䛸ᢳⱏ䛧䜔䛩䛔䛾䛷䚸౑⏝䛩䜛ⱑ䛿᰿㢌ᚄ䠓ࠥ䠔mm⛬
ᗘ䛾䜒䛾䜢౑䛖䚹ᑠ䛥䛺ⱑ䛿䠎䡚䠏ᮏ䜎䛸䜑䛶䠍ᰴ䛸䛩䜛䚹3䠅᥇✀䛿䠏ᖺ┠ᰴ䜘䜚⾜䛖її䠎ᖺ┠⛅䛻཰✭䛧䛺䛔䛷䛭䛾䜎䜎⏿䛷㉺෤䛥䛫䚸䠏ᖺ┠ኟ䛻㛤ⰼ䞉⤖ᐇ䛥䛫᥇✀䛩䜛䚹䝖䜴䜻䛸䝩䝑䜹䜲䝖䜴䜻䛿ᐜ᫆䛻஺㞧䛩䜛䛾䛷䚸୍⥴䛾⏿䛷䛿᱂ᇵ䞉᥇ྲྀ䛧䛺䛔䛣䛸䚹

─ 20 ─

᭶
᪪



୍ᖺ ┠





















஧ᖺ ┠

⏕⫱┦࡜సᴗ

─ 21 ─
⇥ࠉ㓟㸸㹼NJຍࠉ㔛㸸㹼NJ

సᴗࡢෆᐜ

‫཰ۼ‬㔞
ࠉDᙜࡾ㸸㹼NJ‫ۼ‬ㄪᩚࠉඵศ⛬ᗘ஝⇱ᚋࠊ Ỉ୰࡟࡚‫‮‬㏻ࡋࠊⰋࡃᅵ◁ࢆⴠ࡜ࡍ㸬෌ᗘ஝⇱ࡋࠊⱼ㒊ࢆྲྀࡾ㝖ࡃ㸬‫✭཰ۼ‬ⴥ௜ࡁࡢࡲࡲ཰✭ࡋࠊᅵ◁ࢆ᣺ࡾⴠ࡜ࡍ㸬ࠉࣁࢧ➼࡟࠿ࡅ࡚஝⇱ࡍࡿ㸬‫ۑ̿ۑ‬ࠉ཰✭㸦ᐮᆅ㸧‫ڹ̿ڹ‬཰✭㸦ᐮᆅ㸧

䛂⸆⏝᳜≀㻌 ᱂ᇵ䛸ရ㉁ホ౯䛃Part 1 㻔⸆஦᪥ሗ♫䠈1992ᖺ㻕㻌䜘䜚㻌‫ۼ‬ᐃ᳜‫⹸⑓࡞୺ۼ‬ᐖᐃ᳜ⱑ㸸᰿㢌㒊ᚄࡀFP௨ୗࡢⱑ ࠉ࣋ࢺ⑓᮲ࠉ㛫㸸㹼FP⳦᰾⑓ᰴࠉ㛫㸸㹼FP
ࣁࢲࢽ㢮࢟࢔ࢤࣁࡢᗂ⹸

‫ۼ‬ၥᘬࡁ㸸㉸ᐦ᳜ࡢ⟠ᡤࢆ㛫ᘬࡁ ‫ۼ‬㏣⫧ࠉ㸦Dᙜࡾ㸧❅ࠉ⣲㸸NJ‫ࠉ⫧ۼ‬ᩱ㸸↓⫧ᩱ‫ۻ‬ᐃࠉ᳜‫ۻ‬ᐮᆅ‫ۼ‬ᇶ⫧ࠉ㸦Dᙜࡾ㸧᥎ࠉ⫧㸸ࠉࠉ NJ

ᬮᆅ

㏣ ⫧


‫✀᧛ۼ‬㔞㸸GO੍
ࠉࠉࠉGOD‫ۻⱑࠉ⫱ۻ‬‫ۑ̿ۑ‬ᐃ᳜㸦ᬮᆅ㸧
‫ڹ̿ڹ‬
ᐃ᳜㸦ᐮᆅ㸧

‫ۑ̿ۑ‬᧛✀㸦ᬮᆅ㸧‫ڹ̿ڹ‬᧛✀㸦ᐮᆅ㸧ୖ ୰ ୗ ୖ ୰ ୗ ୖ ୰ ୗ ୖ ୰ ୗ ୖ ୰ ୗ ୖ ୰ ୗ ୖ ୰ ୗ ୖ ୰ ୗ ୖ ୰ ୗ ୖ ୰ ୗୖ ୰ ୗ䝖䜴䜻䛾᱂ᇵᬺ

㏣ ⫧─ 22 ─ࢺ࢘࢟࡟㐺⏝ࡢ࠶ࡿ㎰⸆౛᪋㻌 㻌 ⫧㸯 ᖺ┠㸦ⱑᗋ㸧㸰 ᖺ┠ᇶ⫧䠄᧛✀᫬䠅㻌 㻌 㻌 㻌 ሁ⫧䠖 㻌 㻌 㻌 2,000kg/10aⅣ㓟▼⅊䜎䛯䛿ⱞᅵ▼⅊䠖㻌 100kg/10aᇶ⫧䠄ⱑᐃ᳜᫬䠅㻌 㻌 㻌 㻌 ሁ⫧䠖㻌 㻌 㻌 㻌 2,000kg/10aⅣ㓟▼⅊䜎䛯䛿ⱞᅵ▼⅊䠖㻌 㻌 100kg/10a㻌 㻌 㻌 㻌 㻌 㻌 㻌 ❅⣲䠖㻌 6䡚8kg/10a㻌 㻌 㻌 㻌 㻌 㻌 㻌 ⇥㓟䠖 8䡚14kg/10a㻌 㻌 㻌 㻌 㻌 㻌 㻌 ຍ㔛䠖 6䡚8kg/10a㏣⫧䠄䠕᭶ୖ᪪䠅᪋䛥䛺䛔䛛䜎䛯䛿Ἔ䜹䝇䠖㻌 20䡚30kg/10a㻌㻌㻌

㏣⫧䠄䠒 ᭶ୗ᪪䜎䛯䛿䠕᭶䠅㻌 㻌 㻌 㻌 㻌 㻌 㻌 ❅⣲䠖 㻌 6䡚8kg/10a㻌 㻌 㻌 㻌 㻌 㻌 㻌 ຍ㔛䠖 5䡚6kg/10a㻌㻌㸱 ᖺ ┠ 㸦 ✀ Ꮚ᥇ ྲྀ ᫬ 㸧㏣⫧䠄䠐᭶ୗ᪪䡚䠑᭶ୖ᪪䠅㻌 㻌 㻌 㻌 㻌 ❅⣲䠖㻌 㻌 4䡚6kg/10a㻌 㻌 㻌 㻌 㻌 ⇥㓟䠖 4䡚6kg/10a㻌 㻌 㻌 㻌 㻌 ຍ㔛䠖㻌 4 䡚6kg/10a㻌㻌㻌ࠕ⸆⏝᳜≀ ᱂ᇵ࡜ရ㉁ホ౯ࠖPart 1 (薬事日報社，1992年) 改変ᅵተ䛾✀㢮䠈๓స䛾≧ἣ䛻䜘䛳䛶␗䛺䜛䛾䛷䛒䛟䜎䛷୍౛䛷䛒䜛䚹

─ 23 ─

᧛✀䞉⫱ⱑ
✀Ꮚ䛿Ỉ㑅䛧䛶
ỿ䜣䛰䜒䛾䜢౑⏝䛩䜛䚹ⱑᗋ
⣙5cm㛫㝸䛷
䛩䛨᧛䛝䛩䜛䚹

᫓䛻ⱑᗋ䛻᧛✀䚸 JP ࠋ㍍䛟そᅵ䞉㙠ᅽ䛧䚸஝⇱䜢㜵䛠䛯䜑ᩜ䛝⸕䜢⾜䛖䚹Ⓨⱆ㐺 䛿15ࠥ20Υ䚹јⱑᗋ䜲䝯䞊䝆ᅗ㻝㻜㼙㻞䛾ⱑᗋ䛛䜙⣙䠑㼍䛾ᮏ⏿ศ䛾ⱑ䛜䛷䛝䜛䚹㻌

䠏㐌㛫఩䛷
Ⓨⱆ䛜ጞ䜎
䜛䛾䛷䚸ᩜ䛝䝽䝷䜢㝖ཤїј䠍ᖺ㛫⫱ⱑ䚸㻌䠍ᖺ┠䠕᭶୰᪪䛾ᵝᏊ㻌ⱑ䛜኱䛝䛟䛺䜙䛺䛔䜘䛖䛻䚸ሁ⫧䜢ධ䜜䜛⛬ᗘ䛷⫧ᩱ䛿㏻ᖖ᪋⏝䛧䛺䛔䟿඲䛟↓⫧ᩱ≧ែ䛻㏆䛔⏿䛷䛒䜜䜀ሁ⫧䛻ຍ䛘䛶Ἔ䜹䝇䜢䠍㼍ᙜ䜚䠑ࠥ䠒㼗㼓᪋䛩䚹
㏣⫧䜒୚䛘䛺䛔䟿㻌─ 24 ─

ⱑ䛾᥀ୖ䛢䛸㑅ูіј䠎ᖺ┠᫓䛾ⴌⱆ㻌 㻌 㻌 ᳜᭰䛘㐺ᮇјї᣺ື௜䛝
䝕䜺䞊䛷ⱑ䜢
ᇼୖ䛢䜛䚹іј᥀ࡾୖࡆࡓⱑ
─ 25 ─

ⱑ䛾ᐃ᳜䠘ᐃ᳜౛䠚ᰴ㛫20ࠥ25cm
␇ᖜ50ࠥ60 (ࠥ70) cmᩳ䜑᳜䛘䠄45ᗘ䠅⯪ᗏ᳜䛘ᐃ᳜䛾䜲䝯䞊䝆ᅗјјᐃ᳜ࡋࡓⱑ
ᐃ᳜⏝䛾ⱑ䛾㑅ูјї㻌㻌 㻌 㻌 㻌 㻌㻌㻌㻌᰿㢌ᚄ䠓ࠥ䠔㼙㼙⛬ᗘ㻌㻌 㻌 㻌 㻌 䠄䝪䞊䝹䝨䞁఩䛾䜒䛾䠅䛜㻌㻌㻌㻌㻌㻌㻌㻌㻌㻌᭱Ⰻ䚸㻝㻜㼙㼙䛜㝈⏺䚹㻌㻌㻌㻌㻌㻌㻌㻌㻌㻌䛭䜜௨ୖ䛾ⱑ䛿౑䜟䛺䛔䚹㻌  

─ 26 ─

䠎ᖺ⏕ᰴ䛾⏕⫱䠄䝖䜴䜻䛾౛䠅і䠎ᖺ┠䠒᭶୰᪪㻌 㻌㸰ᖺ┠㸵᭶୰᪪ї㻌 㻌 㻌

і㸰ᖺ┠㸷᭶୰᪪ 㻌─ 27 ─

཰✭䞉஝⇱䠄䝖䜴䜻䛾౛䠅䠎ᖺ┠11᭶ࠥ12᭶㡭䛻᣺ືᘧ䝕䜺䞊䛷཰✭䛩䜛䚹ј཰✭ᚋᅵ௜䛝•ⱼⴥ௜䛝䛾䜎䜎䝝䝃᥃䛡஝⇱䛩䜛䚹ї

─ 28 ─

䝝䝃᥃䛡஝⇱ј䝝䝝䝃᥃䛡஝⇱୰䛾ᅵ௜䛝䛾䛾᰿䠄䠏ᖺ┠䠎᭶㡭䛾ᵝᏊ䠅─ 29 ─

཰✭ᚋ䛾ㄪ〇䠄‫‮‬䜒䜏Ὑ䛔సᴗ䠅䐟ј䝖䜴䜻䜢䝫䝸ᐜჾ䛻ධ䜜
60ࠥ70Υ䛾‫‮‬䜢ධ䜜䜛䚹䐠јᯈ䛾ୖ䛷ᅵ◁䜢ⴠ䛸䛧䛺䛜䜙ᥣ䜏Ὑ䛔䛩䜛䚹䐡ј䛭䛾ᚋ䚸ὶỈ䛷䝃䝑䛸Ὑ䛖䚹䐢ј෌䜃䝝䝃᥃䛡䛧䛶஝⇱䛥䛫䜛䚹
─ 30 ─

஝⇱᰿཰㔞䠖
ࠥ250kg/10a200ࠥ஝⇱䛜⤊䛳䛯䜙ᆅୖ㒊䜢ษ䜚ⴠ䛸䛧䛶ฟⲴ㻌 㻌 㻌 㻌 㻌 䠄䠐᭶ୖ᪪䠅ї⏕⸆䝖䜴䜻─ 31 ─

─ 32 ─јј㛤ⰼ⤊ᮇࠊ㸱ᖺ┠㸶᭶୰᪪ࠊ㛤ⰼ⤊ᮇ࡟ј㛤ⰼ┒ᮇࠊ㸱ᖺ┠㸵᭶ୗ᪪ࠥ㸶᭶ୖ᪪ 㸯ᰴᙜࡓࡾ㸲ࠥ㸳ⰼᡣࢆṧࡋ࡚ⰼࢆษ㝖ࡍࡿࠋ㛤ⰼࡣ࣍ࢵ࢝࢖࡟ẚ࡭㸰㐌㛫⛬ᗘ㐜࠸᥇✀㸸㸷᭶ୖ᪪ࠥୗ᪪㸦ࠥ᭶ୖ᪪㸧✀Ꮚࡣ࣓࣒࢝ࢩ࡟
࡟
྾Ồࡉ
ࡉࢀࡿ࡜
࡜ࢩ࢖ࢼ

࡟࡞ࡿࡢ࡛ὀὀពࠋ䛩䜛䚹ј⫱ⱑࠊ㸴᭶ୖ᪪᧛✀ јјᢳⱏ㛤ጞᮇࠊ㸱ᖺ┠㸴᭶ୗ᪪ࠊ 㡬ⰼ䛿㝖ཤ䛩㸯ᖺ┠㸷᭶୰᪪ࡢᵝᏊ   ⱼⰍ㸦㉥⣸㸧ࡸⴥᙧ࣭ⴥⰍࡢᙧ㉁࡛㑅ᢤࠋࢺ࢘࢟ࡢ⣔⤫ಖᏑ࡜᥇✀─ 33 ─ј㛤ⰼ┒ᮇࠊ㸱ᖺ┠㸵᭶ୖ᪪㸵᭶୰᪪㸦㛤ⰼ⤊ᮇ㸧
Ⓩ⇍ᮇࠊ㸱ᖺ┠㸶᭶ୖ᪪࡟㸯ᰴᙜࡓࡾ㸲ࠥ㸳ⰼᡣࢆṧࡋ࡚ⰼࢆษ㝖ࠋ᥇✀㸸㸶᭶୰᪪ࠥ㸷᭶ୖ᪪✀Ꮚࡣ࣓࣒࢝ࢩ࡟
࡟
྾Ồࡉ
ࡉࢀࡿ࡜
࡜ࢩ࢖ࢼ

࡟࡞ࡿࡢ࡛ὀὀពࠋј㛤ⰼጞᮇ(໭ᾏ㐨䛻䛚䛡䜛䠅ј⫱ⱑࠊ㸴᭶ୖ᪪᧛✀ јᢳⱏᮇࠊ㸱ᖺ┠㸴᭶ୖ᪪ࠊ㡬㡬ⰼ䛿㝖ཤ䛩䛩䜛䚹䚹㸯ᖺ┠㸷᭶୰᪪
ⱼⰍ㸦⥳㸧ࡸⴥᙧ࣭ⴥⰍࡢᙧ㉁࡛㑅ᢤࠋ 䝩䝑䜹䜲䝖䜴䜻ࡢ⣔⤫ಖᏑ࡜᥇✀ࢺ࢘࢟㈨ᩱ

㸦᱂ᇵヨ㦂ࢹ࣮ࢱ㸧─ 37 ─）ᘬ⏝ᩥ⊩㸸㧗㔝ࡽࠊᮾி⾨◊ᖺሗࠊ41,62-69 (1990)㸪ᨵኚ）ࢺ࢘࢟ࡢ✀㢮ཬࡧ⏘ᆅ࡟ࡼࡿ⢭Ἔᡂศྵ㔞ࡢẚ㍑ཧ⪃㈨ᩱ

─ 38 ─⛅㐜䛟཰✭䛩䜛䛻䛴䜜䛶஝≀㔜䚸Ṍ␃䜎䜚䛿ୖ᪼䛩䜛䚹䝸䜾䝇䝏䝷䜲䝗ྵ㔞䜒ྠᵝ䛾ഴྥ䜢♧䛩䚹ᘬ⏝ᩥ⊩㸸㛵ᓮࡽ㸪⏕⸆Ꮫ㞧ㄅ㸪38 (4),361-362 (1984) ᨵኚࢺ࢘࢟㸰ᖺ⏕ᰴ࡟࠾ࡅࡿࣜࢢࢫࢳࣛ࢖ࢻྵ㔞ࡢ᫬ᮇูኚ໬                      㸦1978ᖺ㸧ཧ⪃㈨ᩱ

─ 39 ─  ᨵኚ⏕⫱䛻䛿❅⣲䛸䝸䞁㓟䛾ຠᯝ䛜኱䛝䛔䚹⏕⫱Ⰻዲ䛺༊䛿⢭Ἔᡂศྵ㔞䜒㧗䛔䚹ᘬ⏝ᩥ⊩㸸㢗ࡽ㸪⏕⸆Ꮫ㞧ㄅ㸪ࢺ࢘࢟㸰ᖺ⏕ᰴ࡟࠾ࡅࡿ⏕⫱ཬࡧ⢭Ἔᡂศྵ㔞࡟ཬࡰࡍ᪋⫧᮲௳ࡢᙳ㡪ཧ⪃㈨ᩱ

─ 40 ─㸺ᘬ⏝ᩥ⊩㸼ጜᖏࡽ㸸ᙜᖐࡢㄪ〇ἲ࡜໬Ꮫⓗရ㉁ホ౯㸦➨㸵ሗ㸧཰✭᫬ᮇࡢ㐪࠸࡟ࡼࡿᕼ࢚ࢱࣀ࣮࢚ࣝ࢟ࢫ㸪⢾ཬࡧࢹࣥࣉࣥྵ㔞ࡢኚ໬໭ᾏ㐨❧⾨⏕◊✲ᡤሗ࿌㸪  ᨵኚ㢼஝⇱㻟᪥㛫㻌 㻌 䠆䠆䠖ᒇእ䛷䝝䝃᥃䛡஝⇱ᚋ䠈50Υ
ྛ᫬ᮇ10ᰴ䜢᥀䜚ୖ䛢䠈䠑ᰴ䛵䛴౪ヨ䚹㻌䠆䠖50Υ䝝䝃᥃䛡஝⇱ᮇ㛫୰䛻䝕䞁䝥䞁䛜⢾໬䛧䛶ᕼ䜶䝍䝜䞊䝹䜶䜻䝇ྵ㔞䛜ቑຍ䛩䜛䚹⛅㐜䛟཰✭䛧䛯᪉䛜஝≀㔜䠈Ṍ␃䜎䜚䛿ୖ᪼䛩䜛䚹㢼஝⇱㻟᪥㛫㻌

䠄JP17つᐃ್䠖35%௨ୖ䠅䠎ᖺ⏕䝩䝩䝑䜹䜲䝖䜴䜻䛾
䛾ᕼ䜶䝍䝜䞊䝹䜶䜻䝇ྵྵ㔞䛻ཬ䜌䛩཰✭᫬ᮇཬ䜃䝝䝃᥃䛡஝⇱䛾ᙳ㡪䛻ཬ䜌䛩 ཰✭᫬ᮇ ཬ䜃 䝃 ᥃ 䛡 ஝⇱ 䛾 ᙳ 㡪ཧ⪃㈨ᩱ

䝅䝱䜽䝲䜽᱂ᇵ䛻䛴䛔䛶䝅䝱䜽䝲䜽㻌㻌㻌⏕⸆ྡ㸸ࢩࣕࢡࣖࢡ㸦Ⱏ⸆㸧ᇶཎ᳜≀㸸Paeonia lactiflora Pallas (࣎ࢱࣥ⛉)ཎ⏘ᆅ㸸୰ᅜᮾ໭㒊ࠊᮾࢩ࣋ࣜ࢔ࠊἢᾏᕞࠊࣔࣥࢦࣝࠊᮅ㩭༙ᓥ฼⏝㒊఩㸸᰿
ရ㉁つ᱁㸸࣌࢜ࢽࣇࣟࣜࣥ2.0%௨ୖ㸦JP17㸧
⸆ຠ㸸㙠③ࠊ㙠ࡅ࠸ࠊ፬ே⑓ࠊ෭࠼ᛶࠊ⓶⭵⑌ᝈࠊᾘ⅖᤼⮋₎᪉ฎ᪉㸸ᙜᖐⰟ⸆ᩓࠊᅄ≀‫ⴱࠊ‮‬᰿‫≀୐ࠊ‮‬㝆ୗ‫‮‬࡞࡝ࠊ୍⯡⏝₎᪉〇๣294ฎ᪉ࡢෆࠊ99ฎ᪉࡟㓄ྜࠋ⏕⏘ᆅ㸸᪥ᮏ ໭ᾏ㐨ࠊᐩᒣࠊ㛗㔝ࠊ⩌㤿ࠊዉⰋ ୰ᅜ㸦ᅄᕝ┬ࠊύỤ┬ࠊᏳᚯ┬㸧ࢩࣕࢡࣖࢡ

⏕⸆ࢩࣕࢡࣖࢡ㸦᪥ᮏ⏘㸧ㄪ〇ἲ࡟ࡼࡾࠊⓑⰟ㸦ࣅࣕࢡࢩࣕࢡ㸧ࠊ㉥Ⱏ㸦ࢭ࢟ࢩࣕࢡ㸧ࠊ┿Ⱏ㸦ࢩࣥࢩࣕࢡ㸧ࡀ࠶ࡿ ─ 43 ─

䝅䝱䜽䝲䜽䠄Ⱏ⸆䠅䛾つ᱁䠄JP17䠅
䝅䝱䜽䝲䜽
Peony RootPAEONIAE RADIXⰟ⸆ᮏရ䛿䝅䝱䜽䝲䜽Paeonia lactiflora Pallas (Paeoniaceae) 䛾᰿䛷䛒䜛.
ᮏရ䛿ᐃ㔞䛩䜛䛸䛝䠈᥮⟬䛧䛯⏕⸆䛾஝⇱≀䛻ᑐ䛧䝨䜸䝙䝣䝻䝸䞁 (C23H28O11䠖480.46)2.0%௨ୖ䜢ྵ䜐.

⣧ᗘヨ㦂(1) 㔜㔠ᒓ䚾1.07䚿 ᮏရ䛾⢊ᮎ3.0g䜢䛸䜚䠈➨3ἲ䛻䜘 䜚᧯స䛧䠈ヨ㦂䜢⾜䛖.㻌 ẚ㍑ᾮ䛻䛿㖄ᶆ‽ᾮ3.0 mL䜢ຍ䛘䜛(10ppm௨ୗ).
(2) 䝠⣲䚾1.11䚿 ᮏရ䛾⢊ᮎ0.40 g䜢䛸䜚䠈➨4ἲ䛻䜘䜚᳨ᾮ䜢ㄪ〇䛧䠈ヨ㦂䜢⾜䛖(5 ppm௨ୗ).
஝⇱ῶ㔞䚾5.01䚿 14.0%௨ୗ(6᫬㛫).
⅊ศ䚾5.01䚿 6.5%௨ୗ.
㓟୙⁐ᛶ⅊ศ䚾5.01䚿 0.5%௨ୗ.

─ 44 ─

䝅䝱䜽䝲䜽䠄Ⱏ⸆䠅䛾つ᱁䠄JP17䠅⏕⸆䛾ᛶ≧㻌 ᮏရ䛿෇ᰕᙧ䜢࿊䛧䠈㛗䛥7 ࠥ 20 cm䠈ᚄ1 ࠥ 2.5 cm䠈እ㠃䛿〓Ⰽࠥῐ⅊〓Ⰽ䛷䠈᫂䜙䛛䛺⦪䛨䜟ཬ䜃䛔䜌≧䛾ഃ᰿䛾㊧䛸ᶓ㛗䛾⓶┠䛜䛒䜛. ᶓษ㠃䛿⦓ᐦ䛷ῐ⅊〓Ⰽ䜢࿊䛧䠈ᮌ㒊䛿ῐ〓Ⰽ䛾ᨺᑕ≧䛾⥺䛜䛒䜛. ᮏရ䛿≉␗䛺䛻䛚䛔䛜䛒䜚䠈࿡䛿ึ䜑ഹ䛛䛻⏑䛟䠈ᚋ䛻῰ 䛟䛶ഹ䛛䛻ⱞ䛔.
☜ㄆヨ㦂(1) ᮏရ䛾⢊ᮎ0.5g䛻䜶䝍䝜䞊䝹(95) 30 mL䜢ຍ䛘䛶15 ศ㛫᣺䜚ΰ䛬䛯ᚋ䠈䜝㐣䛩䜛. 䜝ᾮ3 mL䛻ሷ໬㕲(III)ヨᾮ1 ⁲䜢ຍ䛘䛶᣺䜚ΰ䛬䜛䛸䛝䠈ᾮ䛿㟷⣸Ⰽࠥ㟷⥳Ⰽ䜢࿊䛧䠈ᚋ䛻ᬯ㟷⣸Ⰽࠥᬯ⥳Ⰽ䛻ኚ䜟䜛.
(2) ᮏရ䛾⢊ᮎ2g䛻䝯䝍䝜䞊䝹10 mL䜢ຍ䛘䠈Ỉᾎୖ䛷5 ศ㛫ຍ䛧䠈෭ᚋ䠈䜝㐣䛧䠈䜝ᾮ䜢ヨᩱ⁐ᾮ䛸䛩䜛. ู䛻䝨 䜸䝙䝣䝻䝸䞁ᶆ‽ရཪ䛿ⷧᒙ䜽䝻䝬䝖䜾䝷䝣䜱䞊⏝䝨䜸䝙䝣 䝻䝸䞁1 mg䜢䝯䝍䝜䞊䝹1 mL䛻⁐䛛䛧䠈ᶆ‽⁐ᾮ䛸䛩䜛. 䛣䜜䜙䛾ᾮ䛻䛴䛝䠈ⷧᒙ䜽䝻䝬䝖䜾䝷䝣䜱䞊䚾2.03䚿䛻䜘䜚 ヨ㦂䜢⾜䛖. ヨᩱ⁐ᾮཬ䜃ᶆ‽⁐ᾮ10
ʅ>䛪䛴䜢ⷧᒙ䜽䝻䝬 䝖䜾䝷䝣䜱䞊⏝䝅䝸䜹䝀䝹䜢⏝䛔䛶ㄪ〇䛧䛯ⷧᒙᯈ䛻䝇䝫䝑 䝖䛩䜛. ḟ䛻䜰䝉䝖䞁/㓑㓟䜶䝏䝹/㓑㓟(100)ΰᾮ
(10: 10:1)䜢ᒎ㛤⁐፹䛸䛧䛶⣙7 cmᒎ㛤䛧䛯ᚋ䠈ⷧᒙᯈ䜢㢼஝䛩䜛.
䛣䜜䛻4-䝯䝖䜻䝅䝧䞁䝈䜰䝹䝕䝠䝗䞉◲㓟ヨᾮ䜢ᆒ➼䛻ᄇ㟝䛧䠈
105㼻
C䛷5ศ㛫ຍ⇕䛩䜛䛸䛝䠈ヨᩱ⁐ᾮ䛛䜙ᚓ 䛯ᩘಶ䛾䝇䝫䝑䝖䛾
䛖䛱1ಶ䛾䝇䝫䝑䝖䛿䠈ᶆ‽⁐ᾮ䛛䜙ᚓ 䛯⣸Ⰽ䛾䝇䝫䝑䝖䛸Ⰽㄪཬ䜃R f್䛜➼䛧䛔.

─ 45 ─

⏕⸆䝅䝱䜽䝲䜽䛾ရ㉁䘆࿴₎⸆䛾Ⰻྰ㚷ูἲཬㄪ〇᪉䠄୍Ⰽ┤ኴ㑻⦅㻌 ྤ㬅ᇽ᭩ᗑ䠅㻌 䘆ኴ䛥ᣦ䛾䜘䛖䛻⬟䛟⫧䛳䛶ሀ䛟䚸እ⓶ῐ⣚Ⰽ䜢ᖏ䜃䚸ෆ㒊ⓑⰍ䜢࿊䛫䜛䚸㛗䛔Წ≧䜢䛺䛧䛶䛒䜛࿡䛾ⱞ䛟῰䛔䜒䛾䛜䜘䜝䛧䛔䚹㻌㻌㻌 䘆⣽䛔䜒䛾䜔䚸▷䛟ᢡ䜜䛯䜒䛾䜔䚸ෆ㒊䛾〓Ⰽ䛻ኚ䛨䛯䜒䛾ཬ䜃⹸㣗䜂䛾䛒䜛䜒䛾䛿䛔䛡䜎䛫䛼䚹㻌㻌䘆⸆⏝᳜≀᱂ᇵ᥇཰ἲ䠄ส⡿㐩ኵ䚸ⱝᯘᴿ
ᅄ㑻ඹⴭ㻌 ༡ᲄ᭩ᗑ䠅㻌㻌 䘆ኴ䛟䛶᩿㠃ⓑⰍ䚸እ㠃ῐ㉥〓Ⰽ䛺䜒䛾䜢Ⰻရ䛸䛩䜛䚹㻌 䘆ྂ䛔䜒䛾䛿ᶓ᩿㠃䛾እ⦕䛜㯮ኚ䛩䜛䚹

─ 46 ─

ⓑⰟ䚸㉥Ⱏ䚸┿Ⱏ䛻䛻䛴䛔䛶㻌㻌᪥ᮏ䛷䛷⏕⏘䛥䛥䜜䜛✀㢮㻌㻌 㻌 㻌 㻌 ⏕ᖸⰟ⸆䠄ⓑⰟ䠖䠅䠖䝅䝱䜽䝲䜽䛾᰿䜢⓶⓶䜢ཤ䛳䛳䛶㻌 㻌 㻌᪥㝜஝⇱㻌㻌 㻌 㻌 㻌 ⏕ᖸⰟ⸆䠄㉥Ⱏ䠖䠅䠖䝅䝱䜽䝲䜽䛾᰿䜢⓶⓶௜䛾䛾䜎䜎㻌 㻌᪥㝜஝⇱㻌₎᪉䛷䛿䛣䛾䠎䛴䜢౑䛖䚹㻌㻌 㻌 㻌 㻌 ┿Ⱏ䠖䝅䝱䜽䝲䜽䛾᰿⓶䜢ཤ䛳䛯ᚋ䛻⇕‫‮‬䛷㻝㻜ศ఩ฎ⌮ᚋ䚸᪥㝜஝⇱䚹㻌 㻌㻌୰ᅜ䛷⏕⏕⏘䛥䜜䜛✀✀㢮㻌 㻌 ⓑⰟ䠖䝅䝱䜽䝲䜽䛾᰿䜢⓶䜢ཤ䛳䛯ᚋ䚸⇕‫‮‬䛷ฎ⌮䛧䛯ᚋ䚸᪥㝜஝⇱䚹㻌 㻌 ㉥Ⱏ䚸ᕝᕝ㉥Ⱏ䠖Paeonia veitchii 䛾᰿䜢⓶௜䛾䜎䜎᪥㝜஝⇱䚹㻌 㻌

Paeonia veitchii㻔୰ᅜ㟷ᾏ┬༡㒊䠄ᅄᕝ┬䛸䛾ቃ䠅䠅㻌 㻌 㻌 㻌 㻌 㻌 㻌 䝅䝱䜽䝲䜽㻌㻌 Paeonia lactiflora Pallas㻌─ 47 ─

࿴Ⱏ䠄䝽䝅䝱䜽䠅 䛸ὒⰟ䠄䝶䜴䝅䝱䜽䠅 䛻䛴䛔䛶
Paeoniaᒓ᳜≀䛿໭༙⌫䛻⣙30ࠥ35✀䛜ศᕸ ࢩࣕࢡࣖࢡ
ࢩࣕࢡ
ࢡࣖࢡ Paeonia lactiflora Pallas   ศᕸ㸸୰ᅜᮾ໭㒊ࠊᮾࢩ࣋ࣜ࢔ࠊᮅ㩭༙ᓥ   㸦ⰼⰍ㸸ⓑⰍࠥ῝⣚Ⰽ䚸Ꮚᡣ䠖↓ẟ䠅䚸㻌㸦ⰼⰍ㸸ⓑⰍࠥ῝⣚Ⰽ䚸Ꮚᡣ䠖↓ẟ䠅䚸 ᪥ᮏ䜈䛾⛣ධᖺ௦䛿୙᫂䚹
㻌 1712ᖺ䠖୰ᅜ䛾䝅䝱䜽䝲䜽᱂ᇵရ✀䛜䜿䞁䝨䝹䛻䜘䜚ึ䜑䛶䝶䞊䝻䝑䝟䛻ఏ䜟䜛䚹
㻌 1732ᖺ䠖䝅䝱䜽䝲䜽㔝⏕✀䛜䝶䞊䝻䝑䝟䛻⤂௓䛥䜜䜛䚹䚹㻌 1772ᖺ䠖䝟䝷䝇䛜䝅䝧䝸䜰㔝⏕ရ䜢䜒䛸䛻䝅䝱䜽䝲䜽䛾Ꮫྡ䜢グ㍕䚹
㻌 1784ᖺ䠖䝒䝳䞁䝧䝸䞊䛾䛂FLORA JAPONIKA䛃䛾୰䛷᪥ᮏ䛾䝅䝱䜽䝲䜽䛜䝶䞊䝻䝑䝟䛻⤂௓䛥䜜䜛䚹 㻌 Paeonia officinalis L.䛾Ꮫྡ䛸䚸Saku Laku䛾࿴ྡ䚹㻌 䜸䝷䞁䝎䝅䝱䜽䝲䜽 Paeonia officinalis L.
   ศᕸ㸸䝶䞊䝻䝑䝟す༡㒊㻌 㻌 㻌 㻌 㻌 䠄ⰼⰍ䠖⣚㉥Ⰽ䚸Ꮚᡣ䠖᭷ẟ䠅䠄䇾ᅬⱁ᳜≀኱㎡඾4䇿ࠊ pp417-426䚸ᑠᏛ㤋䚸ᮾி䠄1989䠅

࿴Ⱏ䠄䝽
䝽䝅䝱䜽䠅
䠅䜎䛯䛿ᅾ
ᅾ᮶ရ✀䠖 Ụᡞ᫬௦䛻᪥ᮏ䛷⫱ᡂ䛥䜜䛯୍㐃䞉࿴䛾䝅䝱䜽䝲䜽ရ✀⩌䚹䞉ὒὒⰟ䠄䝶䝶䜴䝅䝱䜽䠅䠅䠖 䝶䞊䝻䝑䝟䛻Ώ䛳䛶⫱ᡂ䛥䜜䛯ᚋ䚸᪥ᮏ䛻㍺ධ䛥䜜䛯ရ✀⩌䚹㻌 㻌 㻌 㻌 㻌 㻌 ὒⰟ䛻䛿䜸䝷䞁䝎䝅䝱䜽䝲䜽䛸䛾஺㓄✀䜒ΰ䛨䛳䛶䛔䜛䛣䛸䛜⸆⏝✀✀䛸䛧䛶䛿࿴
࿴Ⱏ䛜䛜ዲ䜎䛧䛔䚹
⪃䛘䜙䜜䛣䛸䛛䜙䚸⸆
─ 48 ─ ࢩࣕࢡࣖࢡ᱂ᇵࡢᐇ㝿䝅䝱䜽䝲䜽᱂ᇵ㐺ᆅ䞉ᐮᬮ䛔䛪䜜䛾ᆅᇦ䛷䜒⏕⫱䛩䜛ᗈᇦ㐺ᛂᛶ䜢䜒䛴䛜䚸ཎ⏘ᆅ䛜ᐮ෭ᆅ䛷䛒䜛䛣䛸䚸ᐮ෭ᆅ䛾᪉䛜ⱼⴥ䛾ᯤ䜜ୖ䛜䜚᫬ᮇ䛜㐜䛟⑓ᐖ䛜ᑡ䛺䛔䛣䛸䚸䝨䜸䝙䝣䝻䝸䞁ྵ㔞䛜㧗䛟䛺䜛䛣䛸➼䚻䛜▱䜙䜜䛶䛔䜛䛣䛸䛛䜙䚸෭ᾴ䛺ᆅᇦ䛻㐺䛩䜛䚹䞉ᅵ㉁䛿⪔ᅵ䛜῝䛟䛶䜔䜔⭾㌾䛺◁ተᅵ䡚ᇰተᅵ䛜㐺䛧䛶䛔䜛䚹
䞉⫧Ỻ䛷᤼Ỉᛶཬ䜃ಖỈᛶ䛾Ⰻ䛔ሙᡤ䛻㐺䛩䜛䚹㐣‵䚸≉䛻೵⁫Ỉ䜢᎘䛖䚹䞉䠑ᖺ⏕䛾⛅䛻཰✭ᚋ䚸෤ᮇ䛻䛛䛡䛶⓶๤䛝䚸஝⇱సᴗ䠄ప ୗ䛷䛾⮬↛஝⇱䠅䜢⾜䛖䛯䜑䚸෤ᮇ䛻㞷䛜ከ㔞䛻㝆䜛ᆅᇦ䛷䛿⮬↛஝⇱䛜㞴䛧䛔ࠋࠕ⸆⏝᳜≀ ᱂ᇵ࡜ရ㉁ホ౯ࠖPart 3 (薬事日報社、1994年) 改変
─ 51 ─

䝅䝱䜽䝲䜽᱂ᇵ䛾せⅬ䚸᳜≀䛾≉㉁1䠅⦾Ṫ䛿✀Ꮚ䜒䛧䛟䛿ᰴศ䛡䚹її✀Ꮚ⦾Ṫ䜒ྍ⬟䛷䛒䜛䛜⫱ⱑ䛻䠎ᖺせ䛧䚸䜎䛯䚸ಶయኚ␗䛜ከ䛟䛺䜛䛯䜑䚸⦾Ṫ䛿㏻ᖖᰴศ䛡䛻䜘䜛䚹2䠅⦾Ṫ䠄ᰴศ䛡䠅䛿ᚲ䛪⛅䛻⾜䛖䛣䛸䚹᫓䛻⾜䛖䛸䚸ⴭ䛧䛟ῶ཰䛩䜛䚹
3䠅᱂ᇵ䛻ᖺᩘ䛜䛛䛛䜛її㏻ᖖ䚸ᰴศ䛡ᚋ䚸䠑ᖺ┠䛻཰✭䛩䜛䚹4䠅᰿䛾⫧኱䜢ಁ䛩䛯䜑䛻䚸ⰼ䛿ⷣ䛾᫬䛻䛩䜉䛶㝖ཤ䛩䜛䚹
5䠅ᅬⱁ⏝䜔ษ䜚ⰼ⏝䛻᳜᱂䛥䜜䛶䛔䜛ရ✀䞉⣔⤫䛿䜸䝷䞁䝎䝅䝱䜽䝲䜽䛸䛾஺㓄✀䛜ΰ䛨䛳䛶䛔䜛ྍ⬟ᛶ䛜㧗䛔䛯䜑䚸䛭䜜䜙䛾᰿䛿⸆⏝䛻䛿౑䜟䛺䛔᪉䛜↓㞴䛷䛒䜛䚹─ 52 ─

᭶
᪪ ୖ



୰

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㸯ᖺ┠


୰

⤊
ࠉ 㞷

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ࠉ 㞷

⏕⫱┦࡜సᴗ㸰勖㸲ᖺ┠㸳ᖺ┠

─ 53 ─
㝖ࠉ ⷣ

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ࠉ ✭
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ᆅୖ㒊ᯤṚ

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ᆅୖ㒊ᯤṚ
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㝖ࠉฟ
ཤ

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సᴗࡢෆᐜ

䛂⸆⏝᳜≀㻌 ᱂ᇵ䛸ရ㉁ホ౯䛃Part 3 㻔⸆஦᪥ሗ♫䚸1994ᖺ㻕㻌䜘䜚㻌‫ۼ‬㝖ࠉⲡ
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‫ۼ‬୰ࠉ⪔㸳᭶ࡣⴌⱆࡀฟࡑࢁࡗࡓ㡭ࠊ ᭶ࡣ㏣⫧᪋⏝ᚋ‫ۼ‬᪋ࠉ⫧ 㸦D ᙜࡓࡾ㸧ࠉࠉᇶࠉ⫧ࠉ୰⇍᥎⫧ࠉNJ
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㸦ほ㈹ࡋࡓ࠸ሙྜࡣ‶㛤ࡀࡍࡂࡓࡽ㏿ࡸ࠿࡟᦬ⰼࡍࡿࠋ
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‫ۼ‬㜵ࠉࠉ㝖ࠉ㸴᭶ࠉ⅊Ⰽ࠿ࡧ⑓ࠊ࠺࡝ࢇࡇ⑓ࠊ࢔ࣈ࣒ࣛࢩ࡞࡝
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䝅䝱䜽䝲䜽䛾᱂ᇵᬺ䠄໭ᾏ㐨䠅㻌-ᰴศ䛡ἲ䛾ሙྜ-

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─ 54 ─ࢩࣕࢡࣖࢡ ⸆⏝ ࡟㐺⏝ࡢ࠶ࡿ㎰⸆౛᪋㻌 㻌 ⫧

䠄ᰴศ䛡᱂ᇵ䛾ሙྜ䠅䠍ᖺ┠䠄⛅䛻ⱑᐃ᳜䠅

䠎ᖺ┠

䠏ᖺ┠
㏣⫧䠄5᭶୰᪪䡚ୗ᪪䠅
Ⅳ㓟▼⅊䜎䛯䛿ⱞᅵ▼⅊㻌 100kg/10a㻌㻌 㻌 㻌 㻌 㻌 ❅⣲䠖 7䡚8kg/10a㻌 ⇥㓟䠖 7䡚8kg/10a㻌 㻌 㻌 㻌 㻌 ຍ㔛䠖 7䡚8kg/10a㻌 㻌 㻌 㻌 Ἔ䜹䝇䠖㻌 㻌 40kg/10aᇶ⫧䠄ⱑᐃ᳜๓䠅㻌㻌㻌㻌ሁ⫧䠖㻌 2䡚5t /10aⅣ㓟▼⅊䜎䛯䛿ⱞᅵ▼⅊䠖㻌 100kg/10a㻌 㻌 㻌 㻌 㻌 㻌 Ἔ䜹䝇䠖 40kg/10a䠄⇥㓟䠖䠅䠆
( 10kg/10a)㻌㻌㻌

㏣⫧䠄5᭶୰᪪䡚ୗ᪪䠅䛺䛧䠆䠄㻌 䠅䛿ⅆᒣ⅊ᛶᅵተ䛾ሙྜ

㏣⫧䠄7᭶ୖ᪪䡚୰᪪
㏣⫧䠄7᭶ୖ᪪䡚୰᪪
䜎䛯䛿8᭶ୗ᪪䡚9᭶ୖ᪪䠅㻌 㻌 㻌 㻌 䜎䛯䛿8᭶ୗ᪪䡚9᭶ୖ᪪䠅㻌 㻌 㻌 㻌㻌 㻌 㻌 㻌 㻌 ❅⣲䠖 7䡚8kg/10a㻌 㻌 㻌 㻌 㻌 ❅⣲䠖 7䡚8kg/10a㻌 ⇥㓟䠖 7䡚8kg/10a㻌 ⇥㓟䠖 7䡚8kg/10a㻌 㻌 㻌 㻌 㻌 ຍ㔛䠖 7䡚8kg/10a㻌 㻌 㻌 㻌 㻌 ຍ㔛䠖 7䡚8kg/10a㻌 㻌 㻌 㻌 Ἔ䜹䝇䠖㻌 㻌 40kg/10a㻌 㻌 㻌 㻌 Ἔ䜹䝇䠖 㻌 40kg/10a㏣⫧䠄10᭶୰᪪䠅㻌 㻌 㻌 㻌 㻌 ❅⣲䠖 7䡚8kg/10a㻌 ຍ㔛䠖 7䡚8kg/10a㻌 㻌 㻌 㻌 Ἔ䜹䝇䠖㻌 㻌 40kg/10aᅵተ䛾✀㢮䚸๓స䛾≧ἣ䛻䜘䛳䛶␗䛺
䜛䛾䛷䛒䛟䜎
䛷୍౛䛷䛒䜛䚹

㏣⫧䠄10᭶୰᪪䠅㻌 㻌 㻌 㻌 㻌 ❅⣲䠖 7䡚8kg/10a㻌 ຍ㔛䠖 7䡚8kg/10a㻌 㻌 㻌 㻌 Ἔ䜹䝇䠖㻌
40kg/10a䠐ᖺ┠䠑ᖺ┠䠄⛅䛻཰✭䠅

㏣⫧䠄5᭶୰᪪䡚ୗ᪪䠅
Ⅳ㓟▼⅊䜎䛯䛿ⱞᅵ▼⅊ 100kg/10a㻌㻌 㻌 㻌 㻌 㻌 ❅⣲䠖 7䡚8kg/10a㻌 ⇥㓟䠖 7䡚8kg/10a㻌 㻌 㻌 㻌 㻌 ຍ㔛䠖 7䡚8kg/10a㻌 㻌 㻌 㻌 Ἔ䜹䝇䠖 㻌 40kg/10a㏣⫧䠄5᭶୰᪪䡚ୗ᪪䠅
Ⅳ㓟▼⅊䜎䛯䛿ⱞᅵ▼⅊㻌 100kg/10a㻌㻌 㻌 㻌 㻌 㻌 ❅⣲䠖㻌 7䡚8kg/10a㻌 ⇥㓟䠖 7䡚8kg/10a㻌 㻌 㻌 㻌 㻌 ຍ㔛䠖 7䡚8kg/10a㻌 㻌 㻌 㻌 Ἔ䜹䝇䠖㻌 㻌 40kg/10a㏣⫧䠄7᭶ୖ᪪䡚୰᪪
䜎䛯䛿8᭶ୗ᪪䡚9᭶ୖ᪪䠅㻌 㻌 㻌 㻌㻌 㻌 㻌 㻌 㻌 ❅⣲䠖 7䡚8kg/10a㻌 ⇥㓟䠖 7䡚8kg/10a㻌 㻌 㻌 㻌 㻌 ຍ㔛䠖 7䡚8kg/10a㻌 㻌 㻌 㻌 Ἔ䜹䝇䠖㻌 㻌 40kg/10a㏣⫧䠄7᭶ୖ᪪䡚୰᪪
䜎䛯䛿8᭶ୗ᪪䡚9᭶ୖ᪪䠅㻌 㻌 㻌 㻌㻌 㻌 㻌 㻌 㻌 ❅⣲䠖㻌 7䡚8kg/10a㻌 ⇥㓟䠖 7䡚8kg/10a㻌 㻌 㻌 㻌 㻌 ຍ㔛䠖 7䡚8kg/10a㻌 㻌 㻌 㻌 Ἔ䜹䝇䠖㻌 㻌 40kg/10a㏣⫧䠄10᭶୰᪪䠅㻌 㻌 㻌 㻌 㻌 ❅⣲䠖㻌 7䡚8kg/10a㻌 ຍ㔛䠖 7䡚8kg/10a㻌 㻌 㻌 㻌 Ἔ䜹䝇䠖㻌 㻌 40kg/10a㏣⫧䠄10᭶୰᪪䠅㻌 㻌 㻌 㻌 䛺䛧ࠕ⸆⏝᳜≀ ᱂ᇵ࡜ရ㉁ホ౯ࠖPart 3 (薬事日報社、1994年) 改変
─ 55 ─

᳜௜䛡⏝ⱑ䛾సᡂјⱑ㻌 30ࠥ50g䛷䠑ࠥ10㻌 㻌 ⱆ⛬ᗘ௜䛡䜛**ј᥀ୖࡆࡓᰴ㸦෗┿ࡣ㸱ᖺᰴ㸧*јษ䜚ⴠ䛸䛧䛯᰿䛿⏕⸆⏝䛻䛩䜛䚹
**ⱆᩘ䛜ᑡ䛺䛔ሙྜ䛿䚸䠎ࠥ䠏ಶྜ䜟䛫䛶䠍ᰴ䛸䛩䜛䚹

ј᰿䜢ษ䜚ⴠ䛸䛧䛯ᚋ*䚸ᰴ䠄᰿ⱼ䠅䜢ษ䜚ศ䛡䛶ⱑ䛸䛩䜛䚹

─ 56 ─

ⱑ䛾᳜௜䛡䛸⩣᫓䛾ⴌⱆᐃ᳜䠖䠕᭶ୗ᪪䡚11᭶ୖ᪪㡭䜎䛷䛻᳜௜䛡䜛䚹ⱆ䛿ᚲ䛪ୖ䛻ྥ䛡䜛䚹㸯ᖺ┠㸦๓ᖺ⛅࡟ᐃ᳜ࡋࡓ⩣ᖺ㸧᫓ࡢⴌⱆ

─ 57 ─

ᐃ᳜ᚋ䠎ᖺࠥ䠏ᖺ┠䛾⏕⫱ј䠎ᖺ┠䠒᭶䛾⏕⫱䠄ⰼ䛿ⷣ䛾᫬䛻ⴠ䛸䛩䠅Ќ㸱ᖺ┠᫓ࡢⴌⱆ㻌 䠏ᖺ┠䠒᭶䛾⏕⫱ї䠄ⰼ䛿ⷣ䛾᫬
䛻ⴠ䛸䛩䠅─ 58 ─

ᐃ᳜ᚋ䠐ᖺࠥ䠑ᖺ┠䛾⏕⫱і䠐ᖺ┠䠒᭶䛾⏕⫱䠄ⰼ䛿ⷣ䛾᫬䛻ⴠ䛸䛩䠅ј䠑ᖺ┠䠄཰✭ᖺ䠅䠒᭶䛾⏕⫱䠄ⰼ䛿ⷣ䛾᫬䛻ⴠ䛸䛩䠅
─ 59 ─཰㻌 ✭ј䝕䜺䞊Ќ㸷᭶୰᪪௨㝆ࠊ㸱ᖺ⏕௨ୖࡢᰴࢆ཰✭ࠋ㏻ᖖࡣ㸳ᖺ⏕ᰴࢆ཰✭㸦෗┿ࡣ㸱ᖺᰴ㸧㻌 㻌 㻌 㻌 㻌 ᣺ືᘧ䝕䜺䞊䠄䝞䜲䝤䝻䝇䝟䞊䝋䜲䝷䞊䠅їЌ㤿ຊࢺࣛࢡࢱ࣮࡟⿦╔ࡋࡓࢹ࣮࢞
─ 60 ─

཰✭సᴗіᇼୖసᴗ јЌ᥀ୖࡆࡓᰴЌ 

─ 61 ─

཰✭ᚋ䛾ㄪ〇Ћ᥀ୖࡆࡓᰴ

Ќ᥀ୖ䛢䛯ᰴ䛛䜙᰿䛸᰿ⱼ䜢ศ䛡䜛䠄᰿ⱼ䛿ḟ䛾స௜䛡䛾✀ᰴ䠅䚹─ 62 ─

཰✭ᚋ䛾ㄪ〇䠄ⓑⰟ䛾స〇䠅јỈ䛸◁䜢ධ䜜䛯ᅇ㌿⟽䛻᰿䜢ධ䜜䛶ᅵ◁䛸᰿⓶䜢㝖ཤ䛧 ј䚸ᗈ䛢䛶᪥㝜஝⇱䛩䜛 䚹љ─ 63 ─

཰✭ᚋ䛾ㄪ〇䠄ⓑⰟ䛾స〇䠅ј㻌 ௙ୖ䛜䛳䛯
⏕⸆䝅䝱䜽䝲䜽 ї஝⇱᰿཰㔞䠄┠ᶆ䠅䠖䠖䛷䠍 t/10a௨௨ୖ䠏ᖺ⏕䛷─ 64 ─

─ 65 ─㸦ᘬ⏝ᩥ⊩䠖ᯘࡽࠊ⏕⸆Ꮫ㞧ㄅ64(2)㻢㻤㻙㻣㻡㻌㻔㻞㻜㻝㻜㻕㻚ᨵኚ㸧ෆ㒊䛜ⓑ䛟඘ᐇ䛧䛶௙ୖ䛜䜚䚸䝨䜸䝙䝣䝻䝸䞁ྵ㔞䛜䠎㻑௨ୖ㻌Ᏻᐃ䛧䛶ྵ䜎䜜䜛䜒䛾䜢┠ᶆ䛸䛧䛶ホ౯䛧䛯䚹㻌㻌 ཰✭䛧䛶䠍䜿᭶㛫㈓ⶶᚋ䛻๤⓶䛧䛶஝⇱䛥䛫䜛䛸䚸ෆ㒊䛜ⓑ䛟䚸㻌䝨䜸䝙䝣䝻䝸䞁ྵ㔞䛜㧗䛔⏕⸆䛜ᚓ䜙䜜䜛䚹ᐇ㦂ሙᡤ䠖໭ᾏ㐨⸆⏝᳜≀᱂ᇵヨ㦂ሙ䠄໭ᾏ㐨ྡᐤᕷ)ᮦᩱ䠖໭ᐓ┦㻌 䠏ᖺ⏕ᰴ཰✭᪥䚸཰✭ᚋ䛾᰿䛾㈓ⶶᮇ㛫ཬ䜃⓶๤䛝䠄䠙ㄪ〇䠅᫬ᮇ䛾ᙳ㡪ཧ⪃㈨ᩱ

䝅䝱䜽䝲䜽䛾⸆⸆⏝ရရ✀䛻䛻䛴䛔䛶㻌㻌

་⸆ᇶ┙◊✲ᡤ㻌⸆⏝᳜≀㈨※◊✲䝉䞁䝍䞊໭ᾏ㐨◊✲㒊䛷⥔ᣢ䛧䛶䛔䜛61⣔⤫䊺㻌ዉⰋ┴䛷ྂ䛟䛛䜙⸆⏝✀䛸䛧䛶⥔ᣢ䛥䜜䛶䛔䜛⣔⤫䛂Კኳ䛃䠄ⓑⰼ䚸ඵ㔜䠅䊺䊺㻌─ 66 ─㻌 㻌 㻌 㻌 ⸆⏝ရ✀䛂໭ᐓ┦䛃㻌
ရ✀Ⓩ㘓䠄1996ᖺ䚸No.5005䠈 ␊ᒣ䜙䠅໭ᐓ┦㻌㻥᭶ୖ᪪䛻䛚䛡䜛ᯤ䜜ୖ䛜䜚䛾ẚ㍑㻌

䛂໭ᐓ┦䛃䛾ⰼ䛂໭ᐓ┦䛃䛾᰿䛂໭ᐓ┦䛃䛾᰿ရ✀䛾≉㛗䠖ⴥ䛾ᯤ䜜ୖ䛜䜚䛜㐜䛔䛯䜑䚸㧗཰㔞䜢♧䛩䚹
Paeoniflorinྵ㔞䛜Ᏻᐃ䛧䛶JPつ᱁್䜢༑ศ䜽䝸䜰䛩䜛䚹
Gallotanninྵ㔞䛜ẚ㍑ⓗ㧗䛔䚹ḞⅬ䛿albiflorin ྵ㔞䛜ప䛟䠄0.02
ࠥ0.06%)䚸᰿䛾Ⰽ䛜㉥䜏䜢ᖏ䜃䚸஝⇱䛩䜛䛸ⓑ䛟௙ୖ䛜䜙䛺䛔䚹䛂໭ᐓ┦䛃䛾ⰼ஝⇱᰿཰㔞䠄10aᙜ䛯䜚䠅㻌䠏ᖺ⏕㻌 1,266kg
䠑ᖺ⏕㻌 1,674ࠥ 2,342kg

Paeoniflorin㻌㻌 䠏ᖺ⏕ 3.9䠂䠗㻌 㻌 䠑ᖺ⏕㻌 4.4ࠥ4.8䠂
Gallotannin㻌㻌 䠏ᖺ⏕㻌 0.29䠂䠗䠑ᖺ⏕㻌 0.36䠂䠄ᘬ⏝ᩥ⊩䠖␊ᒣ䜙䚸Nat. Med. 52, 103-108 (1998)䜘䜚䠅㻌─ 67 ─㻌 㻌 ⸆⏝ရ✀䛂䜉䜉䛻䛧䛪䛛䛃
ရ✀Ⓩ㘓䠄2015ᖺ䚸No. 24367䠈⳻⏣䜙䠅㻌㻌
ᰴศ䛡䠏
䠏ᖺ┠ᰴ
ᰴ䛾㛤ⰼ≧ἣẚ㍑

໭ᐓ┦㻌䜉䛻䛧䛪䛛㻌
䜉䛻䛧䛪䛛㻌

䛂䜉䛻䛧䛪䛛䛃䛾᰿ရ✀䛾≉㛗䠖㻌
㛤ⰼ⋡䠑㻑䛸ప䛔䛯䜑䚸᦬ⷣసᴗ
䛜䜋䜌┬␎ྍ⬟䚹໭ᐓ┦䛻ẚ䜉䚸㻌
཰㔞ᛶ䛿ຎ䜛䛜䚸
paeoniflorinྵ㔞䛿䜋䜌ྠ➼䚸
gallotanninྵ㔞䜔albiflorinྵ㔞䛿㧗䛔䚹
᰿䛾Ⰽ䛿ⓑ䛔䚹

㻺㻻㻚㻚㻌㻡㻡㻝㻥㻌㻌䛂䜉䛻䛧䛪䛛䛃䛾ⰼ஝⇱᰿཰㔞䠄10aᙜ䛯䜚䠅䠏ᖺ⏕㻌 535ࠥ914kg

Paeoniflorin䠏ᖺ⏕㻌 4.30ࠥ4.77䠂
Gallotannin䠏ᖺ⏕㻌 0.43ࠥ0.74䠂
Albiflorin䠏ᖺ⏕㻌 0.26ࠥ0.30䠂 㸦ᘬ⏝ᩥ⊩䠖ᯘ䜙䚸⏕⸆Ꮫ㞧ㄅ㻌65(2),129-133㸦2011) ࡼࡾ㸧
─ 68 ─

䝉䞁䜻䝳䜴᱂ᇵ䛻䛴䛔䛶䝉䞁䜻䝳䜴㻌㻌
⏕⸆ྡ䠖䝉䞁䜻䝳䜴䠄ᕝᕝⰠ䠅㻌ᇶཎ᳜≀䠖Cnidium officinale Makino 㻔䝉䝸⛉㻕㻌㻌ཎ⏘ᆅ䠖୰ᅜ䠄㔝⏕ᰴ䛿䜏䛴䛛䛳䛶䛔䛺䛔䠅㻌฼⏝㒊఩䠖᰿ⱼ㻌⸆ຠ䠖㈋⾑ࠊ ෭䛘⑕ࠊ ⓶⭵⑌ᝈࠊ ᾘ⅖᤼⮋㻌₎᪉ฎ᪉䠖ᙜᖐⰟ⸆ᩓ䚸ᅄ≀‫‮‬䚸㜵㢼㏻⪷ᩓ䚸㻌㻌 㻌 ༑࿡ᩋẘ‫‮‬䛺䛹䚸୍⯡⏝₎᪉〇๣㻞㻥㻠ฎ᪉䛾ෆ䚸㻌㻌 㻌 㻡㻞ฎ᪉䛻㓄ྜ䛥䜜䜛䚹㻌⏕⏘ᆅ䠖᪥ᮏ䠄໭ᾏ㐨䚸ᮾ໭䚸㛵ᮾ໭㒊㻕㻌㻌 㻌 㻌 㻌 ୰ᅜ䠄ᮾ໭㒊䚸ᅄᕝ┬㻕㻌㻌㻌 㻌 㻌 㻌 㻌㻌㻌 ⏕⸆ྡ䛿ྠ୍䛷䛒䛳䛶䜒᪥ᮏ䛸୰ᅜ䛷䛿䛭䛾ཎ᳜≀䛜␗䛺䜛㻔Ligusticum chuanxiong Hort㻚㻕䛯䜑䚸᪥ᮏ䛛䜙✀䜲䝰䛜୰ᅜ䜈ᣢ䛱㎸䜎䜜䚸⏕⏘䛥䜜䛶᪥ᮏ䜈㍺ධ䛥䜜䛶䛔䜛䜒䛾䛜䛒䜛䚹㻌ࢭࣥ࢟ࣗ࢘

⏕⸆ᕝⰠ㸦໭ᾏ㐨⏘㸧─ 71 ─

䝉䞁䜻䝳䜴䠄ᕝⰠ䠅䛾つ᱁䠄JP17䠅
䝉䞁䜻䝳䜴
Cnidium Rhizome
CNIDII RHIZOMAᕝⰠᮏရ䛿䝉 䞁 䜻 䝳 䜴 Cnidium officinale Makino(Umbelliferae)䛾᰿ⱼ䜢䠈㏻౛䠈‫‮‬㏻䛧䛧䛯䜒䛾䛷䛒䜛.
⣧ᗘヨ㦂(1) 㔜㔠ᒓ䚾1.07䚿 ᮏရ䛾⢊ᮎ3.0g䜢䛸䜚䠈➨3ἲ䛻䜘 䜚᧯స䛧䠈ヨ㦂䜢⾜䛖. ẚ㍑ᾮ䛻䛿㖄ᶆ‽ᾮ3.0 mL䜢ຍ䛘䜛(10 ppm௨ୗ).
(2) 䝠⣲䚾1.11䚿 ᮏရ䛾⢊ᮎ0.40g䜢䛸䜚䠈➨4ἲ䛻䜘䜚 ᳨ᾮ䜢ㄪ〇䛧䠈ヨ㦂䜢⾜䛖(5 ppm௨ୗ).
⅊ศ䚾5.01䚿 6.0%௨ୗ.
㓟୙⁐ᛶ⅊ศ䚾5.01䚿 1.0%௨ୗ.
㈓ἲᐜჾ ᐦ㛢ᐜჾ.

─ 72 ─

䝉䞁䜻䝳䜴䠄ᕝⰠ䠅䛾つ᱁䠄JP17䠅⏕⸆䛾ᛶ≧㻌 ᮏရ䛿୙つ๎䛺ሢ≧䜢࿊䛧䠈䛸䛝䛻䛿⦪๭䛥䜜,㛗䛥5 ࠥ 10 cm䠈ᚄ3 ࠥ 5 cm䛷䛒䜛. እ㠃䛿⅊〓Ⰽࠥᬯ〓Ⰽ䛷䠈㔜䛺䜚ྜ䛳䛯⤖⠇䛜䛒䜚䠈䛭䛾⾲㠃䛻䛣䜆≧䛾㝯㉳䛜䛒䜛.㻌 ⦪᩿㠃䛿㎶⦕䛜୙ᩚ䛻ศᯞ䛧䠈ෆ㠃䛿⅊ⓑⰍࠥ⅊〓Ⰽ䠈༙㏱᫂䛷䛸䛝䛻䛿䛖䛴䜝䛜䛒䜛. ᮏရ䛾㉁䛿ᐦ䛷ሀ䛔. 㻌 㻌 㻌 㻌 㻌 㻌 㻌 㻌 㻌 㻌 㻌ᮏရ䛿≉␗䛺䛻䛚䛔䛜䛒䜚䠈࿡䛿ഹ䛛䛻ⱞ䛔.㻌 㻌 㻌 㻌 㻌 㻌 㻌 㻌ᮏရ䛾ᶓษ∦䜢㙾᳨䚾5.01䚿䛩䜛䛸䛝䠈⓶㒊ཬ䜃㧊䛻䛿Ἔ㐨䛜ᩓᅾ䛩䜛. ᮌ㒊䛻䛿ཌቨ䛷ᮌ໬䛧䛯ᮌ㒊⧄⥔䛜኱ᑠ୙ྠ䛾⩌䜢䛺䛧䛶Ꮡᅾ䛩䜛. 䛷䜣䜇䜣⢏䛿䠈㏻౛䠈⢶໬䛧䛶䛔䜛䛜䠈䜎䜜䛻ᚄ5 ࠥ 25 ʅŵ䛾⢏䛸䛧䛶ㄆ䜑䜛䛣䛸䛜䛒䜛. 䝅䝳 䜴㓟䜹䝹䝅䜴䝮䛾⤖ᬗ䛿ㄆ䜑䛺䛔.

─ 73 ─

⏕⸆䝉䞁䜻䝳䜴䛾ရ㉁䘆࿴₎⸆䛾Ⰻྰ㚷ูἲཬㄪ〇᪉䠄୍Ⰽ┤ኴ㑻⦅㻌 ྤ㬅ᇽ᭩ᗑ䠅 㻌㻌 䘆⌫ᙧ䛒䜛䛔䛿㛗෇ᙧ䛾ሢ≧᰿䛷䛒䛳䛶䚸እ⓶䛜㯮〓Ⰽ䡠ෆ㒊䛜㯤ⓑⰍ䛷䚸኱䛝䛟䛶Ẽ࿡䛾㎞Ⅿ䛺䜛䜒䛾䛜䜘䛔㻌䚹㻌㻌㻌䘆⸆⏝᳜≀᱂ᇵ᥇཰ἲ䠄ส⡿㐩ኵ䚸ⱝᯘᴿ
ᅄ㑻ඹⴭ㻌 ༡ᲄ᭩ᗑ䠅㻌 䘆ᅵ◁䛾௜╔䛧䛯䜒䛾䚸᫓ᇼ䜚䛾䜒䛾䚸᰿⌫㐃᥋䛧䛯䜒䛾䛿୙Ⰻ䛷䛒䜛䚹

─ 74 ─

᪥ᮏ䛾ᕝⰠ䠄䛫䜣䛝䜕䛖䠅䛸୰ᅜ䛾ᕝⰠ(Chuanxiong)䛿ඖ䛻䛺䜛᳜≀䠄ᇶཎ᳜≀䠅䛜␗䛺䜛䟿 ୰ᅜ࡛ࡶᕝⰠࡣ౑ࢃࢀ࡚࠸ࡿࡀࠊ୰ᅜ䛷䛿䝖䜴䝉䞁
䜻䝳䜴Ligusticum chuanxiong Hort 䛾஝⇱䛧䛯᰿ⱼ䛸つᐃ䛥䜜䛶䛔䜛䚹㻌 ྠ䛨䝉䝸⛉ 䛾᳜≀䛷䛒䜛䛜䚸ูᒓู✀䛾᳜≀䛜౑⏝䛥䜜䛶䛔䜛䚹䛣䛾䜘䛖䛻⏕⸆ྡࡣྠ୍࡛࠶ࡗ࡚
ࡶ᪥ᮏ࡜୰ᅜ࡛ࡣࡑࡢཎ᳜≀ࡀ␗࡞ࡿࡓࡵࠊ᪥ᮏ࡛ࡣ
୰ᅜ⏘ᕝⰠࡣ౑࠼࡞࠸ࠋ
䝖䜴䜻䛾ሙྜ䜒ྠ䛨䜿䞊䝇䛷䛒䜛䚹Ĺ㻌 ࢭࣥ࢟ࣗ࢘
Cnidium officinale MakinoĹ㻌 䝖䜴䝉䞁䜻䝳䜴
Ligusticum chuanxiong Hort
─ 75 ─ ࢭࣥ࢟ࣗ࢘᱂ᇵࡢᐇ㝿䝉䞁䜻䝳䜴䛾᱂ᇵ㐺ᆅ䞉⪏ᐮᛶ䛿ᙉ䛟䚸⪏ᬬᛶ䛿ᙅ䛔䛯䜑䚸ኟᮇ෭ᾴ䛺ᆅ᪉䛜㐺䛧䛶䛔䜛䚹㻌 ኟ䛻㧗 䞉ከ‵䛜⥆䛔䛯䜚䚸ᖸ䜀䛴䛻䛺䜛䛸䚸ⲡໃ䛜ᙅ䜚䚸⑓⹸ᐖ䛜ከⓎ䛧䛶ῶ཰䛾ཎᅉ䛸䛺䜛䚹≉䛻䚸ᆅୗ㒊䠄ሢ᰿㸧ࡀ⫧኱ࡍࡿ㸷᭶௨㝆࡟Ẽࡀపୗࡍࡿᆅᇦ࡛ࡢ᱂ᇵ࡟㐺ࡋ࡚࠸ࡿࠋࡇ
ࡢࡓࡵࠊ᪥ᮏ䛷䛿໭ᾏ㐨䚸ᮾ໭ࠥ㛵ᮾ໭㒊ᆅ᪉䛜᱂ᇵ㐺ᆅ䛸䛥䜜䛶䛔䜛䚹 䞉ᅵተ䛿᤼Ỉᛶ䛜Ⰻዲ䛺⏿䛜Ⰻ䛟䚸ᆅୗỈ఩䛾㧗䛔䛸䛣䜝䛷䛿䚸༑ศ⏕⫱䛧䛺䛔䚹᫓ඛ䛻㞷ゎ䛡Ỉ䛜೵⁫䛩䜛䛸ሢ᰿ࡣ⭉ࡗ࡚ᯤṚࡍࡿࠋ䞉⛅䛻཰✭䛧䚸✀䜲䝰䜢ᐃ᳜䛩䜛䛾䛷䚸⛅㞵䛜ከ䛔ᆅᇦ䛷䛿సᴗ䛻 ᅔ㞴䜢䛝䛯䛩䚹䛂⸆⏝᳜≀㻌 ᱂ᇵ䛸ရ㉁ホ౯䛃Part 2㻌㻔⸆஦᪥ሗ♫䚸㻝㻥㻥㻟ᖺ㻕㻌䜘䜚㻌─ 79 ─

䝉䞁䜻䝳䜴᱂ᇵ䛾せⅬ䚸᳜≀䛾≉㉁1䠅ᢳⱏ䛿䜎䜜䛷䛒䜛䛜䚸䠎ᖺ┠௨㝆䛿඲ᰴᢳⱏ䞉㛤ⰼ䛩䜛䚹㛤ⰼ䛧䛶䜒ᰁⰍయ୙ᑐྜ䛾䛯䜑✀Ꮚ䛜䛷䛝䛺䛔䚹її⦾Ṫ䛿ሢ᰿࡟ࡼࡿ䚹
2䠅᱂ᇵᙧែ䛸᱂ᇵᖺᩘ䠖⛅䛻✀䜲䝰䠄ሢ᰿㸧ࢆᐃ᳜ࡋࠊ⩣᫓࡟ⴌⱆࡋࡓᚋࠊ⛅࡟᥀ࡾୖࡆ
࡚཰✭ࡋࠊ᥀ࡾୖࡆࡓሢ᰿ࡢ୍㒊ࢆ⩣ᖺࡢ⦾Ṫ⏝࡟⏝࠸ࠊṧࡾࢆ⏕⸆࡜ࡋ࡚ㄪ〇ຍᕤࡍࡿ㸦㉺ᖺ㸰ᖺ᱂ᇵ㸧ࠋ⠇㛫䛜ఙ㛗䛧䛶䝋䝻䝞䞁⋢≧䛻䛺䛳䛯ሢ᰿ࢆࠕ䝋䝻䝞䞁᰿䛃䛸࿧䜃䚸⦾Ṫ䛻䛿౑䜟䛺䛔䚹⏕⸆䛸䛧䛶䜒ຎရ䛸䛺䜛䠄ᐇ㟂⪅䛻䜘䛳䛶䛿㈙䛳䛶䜒䜙䛘䛺䛔䠅䚹3䠅⦾Ṫ䛿ᚲ䛪⛅䛻⾜䛖䚹᫓䛻⾜䛖䛸䚸ⴭ䛧䛟ῶ཰䛩䜛䚹

─ 80 ─

䝉䞁䜻䝳䜴䛾᱂ᇵᬺ䠄໭ᾏ㐨䠅஧ᖺ ┠‫ڹ̿ڹ‬
ࠉ㏣⫧⏕⫱┦࡜సᴗ

సᴗࡢෆᐜ

─ 81 ─

䛂⸆⏝᳜≀㻌 ᱂ᇵ䛸ရ㉁ホ౯䛃Part 2㻔⸆஦᪥ሗ♫䠈1993ᖺ㻕㻌ᨵኚ㻌䠄཰㔞䛿⩣ᖺ䛾✀䜲䝰ศ䜢㝖䛔䛶䛺䛟䠈䛩䜉䛶䜢⏕⸆⏝䛻౑⏝䛧䛯ሙྜ䛾ᩘᏐ䠅‫ڹ̿ڹ ̿ڹ ڹ̿ڹ‬ࠉ ࠉ⑓⹸ᐖ㜵㝖ࠉ ཰✭ Ὑίࠊ‫‮‬㏻ࡋࠊ஝⇱ࠉḟᖺస⏝✀࢖ࣔ‽ഛ‫ڹ̿ڹ‬
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㝖ⲡ
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㝖ⲡ
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‫ۼ‬ᇶ⫧ࠉ㸦Dᙜࡾ㸧㸸‫ۼ‬㝖ⲡ๣㸸   ‫✭཰ۼ‬㸸ⴥࡀ㯤Ⰽࢆᖏࡧ࡚ࡁࡓࡽᆅୖ㒊ࢆสࡾྲྀࡾࠊ
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‫⑓ۼ‬ᐖ⹸㜵㝖㸸
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ࠉࠉ᰿⭉⑓㸸࣮࣋ࣥࣞࢺỈ࿴๣㸦✀࢖ࣔᾘẘ㸧ࠉࠉࠉࠉࠉࠉ
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ࠉࠉ࣋ࢺ⑓㸸࢚࣒ࢲ࢖ࣇ࢓࣮
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ࠉࠉ࠺࡝ࢇࡇ⑓㸸ࢲࢥࢽ࣮࢚࣮ࣝࢫ
ࠉࠉ✀࢖ࣔ㸸㹼NJ ࡚௙ୖࡆࡿࠋ
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ࠉࠉࡑࡢ௚㸸㔝⳯㢮࡟㐺⏝ࡢ࠶ࡿ㎰⸆ࠉࠉᰴࠉ㛫㸸FP‫཰ۼ‬㔞㸸Dᙜࡓࡾ஝⇱ရ࡛㹼NJ
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ࠉࠉࠉࠉᰴ࡜ࡍࡿ㸧ࠉࠉࠉ ‫ۼ‬㏣⫧㸦Dᙜࡾ㸧㸸
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ࠉࠉⱆࢆᚲࡎୖྥࡁ࡟᳜࠼ࠊ
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ࠉࠉ㸳᭶୰㹼ୗ᪪㸸໬ᡂ⫧ᩱࠉ1㸸.
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ࠉࠉそᅵࡣFP⛬ᗘ⾜࠺ࠋ
‫ۑ̿ۑ‬
ⴌⱆ

‫ڹ̿ڹڹ̿ڹ‬ᩚᆅ࣭ᇶ⫧✀࢖ࣔᾘẘ࣭ᐃ᳜

᭶

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᪪ ୖ ୰ ୗ ୖ ୰ ୗ ୖ ୰ ୗ ୖ ୰ ୗ ୖ ୰ ୗ ୖ ୰ ୗ ୖ ୰ ୗ ୖ ୰ ୗ ୖ ୰ ୗ ୖ ୰ ୗ ୖ ୰ ୗୖ ୰ ୗ୍ᖺ ┠─ 82 ─ࢭࣥ࢟ࣗ࢘࡟㐺⏝ࡢ࠶ࡿ㎰⸆౛᪋㻌 㻌 ⫧
䠍ᖺ┠䠄⛅䛻✀䜲䝰ᐃ᳜䠅㻌 㻌 㻌 㻌 䠎ᖺ┠䠄⛅䛻཰✭䠅ᇶ⫧㻌 䠄✀䜲䝰ᐃ᳜᫬䠅㻌㻌㻌㻌㻌ሁ⫧䠖 2,000kg/10aⅣ㓟▼⅊䜎䛯䛿ⱞᅵ▼⅊䠖㻌 100kg/10a㻌 㻌 㻌 㻌 㻌 㻌 㻌 ❅⣲䠖㻌 㻌 㻌 6kg/10a㻌 㻌 㻌 㻌 㻌 㻌 㻌 ⇥㓟䠖 㻌 6kg/10a㻌 㻌 㻌 㻌 㻌 㻌 㻌 ຍ㔛䠖㻌
6kg/10a㻌㻌㻌

㏣⫧䠄䠑᭶୰䡚ୗ᪪䠅㻌 㻌 㻌 㻌 㻌 㻌 ❅⣲䠖㻌 6䡚8kg/10a㻌 㻌 㻌 㻌 㻌 㻌 ຍ㔛䠖 4䡚6kg/10a㏣⫧䠄䠔᭶ୖ᪪䠅䠘⏕⫱≧ែ䛻䜘䜚ุ᩿䠚㻌 㻌 㻌 㻌 㻌 㻌 ❅⣲䠖 㻌 㻌 3kg/10a㻌 㻌 㻌 㻌 㻌 㻌 ຍ㔛䠖㻌 2䡚3kg/10a㻌㻌ࠕ⸆⏝᳜≀ ᱂ᇵ࡜ရ㉁ホ౯ࠖPart 2 (薬事日報社、1993年) 改変ᅵተ䛾✀㢮䚸๓స䛾≧ἣ䛻䜘䛳䛶␗䛺䜛䛾䛷䛒䛟䜎䛷୍౛䛷䛒䜛䚹

─ 83 ─

✀䜲䝰䛾ᐃ᳜

Ќ᥀ࡾୖࡆࡽࢀࡓᆅୗ㒊㸦⛅㸧Ꮚ䜲䝰䜢䛿䛜䛧䛶
✀䜲䝰䛻䛩䜛䚹

јᅡሙ䜈䛾ᐃ᳜䠄⛅䛾సᴗ䠅そᅵ䛿䠎cm⛬ᗘ䛻䛩䜛䟿そЌ᳜௜ࡅ⏝ࡢ✀࢖ࣔ㸦⛅㸧✀䜲䝰䛿ᚲ䛪䝧䞁䝺䞊䝖䛷ẅ⳦䛧䛶䛛䜙ᐃ᳜䛩䜛䟿─ 84 ─

ᚲ䛪ⱆ䜢
ୖ䛻ྥ䛡䛶
᳜䛘䜛䟿䟿

ࢯࣟࣂࣥ᰿࡟ࡘ࠸࡚
䝋䝻䝞䞁
䝋䝻䝞䞁

䝋䝻䝞䞁

䝋䝻䝞䞁

ࢯࣟࣂࣥ᰿ࡀከⓎࡋࡓᰴ⠇㛫䛜ఙ㛗䛧䛶䝋䝻䝞䞁⋢䛾䜘䛖䛻䛺䛳䛯᰿ⱼ䜢䛂䝋䝻䝞䞁᰿䛃䛸࿧䜆䚹䝋䝻䝞䞁᰿䛿✀䜲䝰䛻䛿౑⏝䛧䛺䛔䚹䜎䛯䚸⏕⸆䛸䛧䛶䛾ရ㉁䛜ຎ䜛䚹

─ 85 ─

᫓䛾ⴌⱆཬ䜃⏕⫱ึᮇ䛾ᵝᏊ䠄໭ᾏ㐨໭㒊䠅јⴌⱆ䚸㞷ゎ䛡ᚋ䠍㐌㛫䚸䠐᭶ୗ᪪ј⏕⫱ึᮇ䚸䠑᭶୰ࠥୗ᪪
㻌 ㏣⫧䛾㐺ᮇ䟿

─ 86 ─

⏕⫱୰ࠥ┒ᮇ䛾ᵝᏊ䠄໭ᾏ㐨໭㒊䠅ј⏕⫱୰ᮇ䚸䠒᭶ୖ᪪ј ⏕⫱┒ᮇ䚸䠓᭶ୖ᪪䛣䛾᫬ᮇ䛻䝝䝎䝙
䜔⑓ᐖ䛻䜘䜚ᆅୖ㒊䛜䝎䝯䞊䝆䜢ཷ䛡䜛䛸ⴭ䛧䛟ῶ཰䛩䜛䛾䛷䚸㜵㝖䜢ᚲ䛪⾜䛖䟿ј⏕⫱┒ᮇ䚸䠔᭶ୖ᪪㻌 ᚎ䚻䛻␇㛫䛜䜅䛥䛜䛳䛶䛟䜛䚹─ 87 ─

⏕⫱┒ᮇࠥ⤊ᮇ䛾ᵝᏊ䠄໭ᾏ㐨໭㒊䠅Ⰻዲ䛺⏕⫱≧ែ䛾⏿ј⏕⫱⤊ᮇ䠄ᆅୗ㒊⫧኱䚸඘ᐇ䠅䚸䠕᭶ୖ᪪␇㛫䛜䜋䜌䜅䛥䛜䛳䛶䛟䜛䚹─ 88 ─

཰㻌 ✭䠄໭ᾏ㐨໭㒊䠅᣺ື௜䛝䝕䜺䞊䠄䝞䜲䝤䝻䝇䞊䝟䞊䝋䜲䝷䞊䚸K ♫〇ࠊ
30㤿ຊ௨ୖ䛾䝖䝷䜽䝍䞊䛻⿦╔ 䠅䛻䜘䜛཰✭౛䚹䠕᭶ୗ᪪ࠥ10᭶ୖ᪪䚹䜋䜌᏶඲䛻᥀ୖ䛢䜛䛣䛸䛜䛷䛝䜛䚹㻌 ⴥ䛜䜔䜔㯤Ⰽ࿡䜢ᖏ䜃䛶䛝䛯㡭䛛䜙䛜㐺ᮇ䚹⛅㐜䛟཰✭䛧䛯᪉䛜཰㔞䛿ୖ䛜䜛䛜䚸ḟᖺᗘ⏝䛾᳜䛘௜䛡䜢⾜䛖㛵ಀ䛷10᭶ୖࠥ୰᪪䜎䛷䛻䛿཰✭䛩䜛ᚲせ䛜䛒䜛䚹─ 89 ─

཰✭ࡋࡓᆅୗ㒊
䝋䝻䝞䞁᰿

Ĺṇᖖ࡞ᰴ
୰ᚰ䛻ぶ䜲䝰䛜䛒䜚䚸࿘䜚䜢ྲྀ䜚ᅖ䜐䜘䛖䛻Ꮚ䜲䝰䛜䛷䛝䜛䚹Ĺࢯࣟࣂࣥ᰿ࡀከⓎࡋࡓᰴ㻌 㻌 㻌 㻌 㻌 㻌 㻌 㻌 ཰㔞䛻䛴䛔䛶཰ 㔞 䛻䛴䛔 䛶Ќ᳜௜ࡅ⏝ࡢ✀࢖ࣔ⏕᰿䛾཰✭㔞:㻌 㻌 㻌 㻌 㻌 2,000kgࠥ2,500kg/10a✀䜲䝰⏝䠖㻌 ⣙270kg/10a䠄30g㽢9,000ᰴ䠅⏕⸆⏝䠄✀䜲䝰ศ䜢㝖䛔䛯㔜㔞䠅䠖㻌 㻌 㻌 㻌 㻌 㻌 1,730ࠥ2,230kg/10a஝⇱Ṍ␃䜎䜚䠖30%䛸௬ᐃ䛩䜛஝⇱᰿㔜㔞䠖520ࠥ670kg/10a

─ 90 ─

ࢭࣥ࢟ࣗ࢘ཧ⪃㈨ᩱ
㸦᱂ᇵヨ㦂ࢹ࣮ࢱ㸧ཧ⪃㈨ᩱ

Ꮚ䜲䝰䛜ศ໬䛧䛶䛟䜛䛾䛿䠒᭶୰䡚ୗ᪪䛛䜙䛷
䛒䜚䚸௨ᚋḟ䚻䛸Ꮚ䜲䝰䜢ᙧᡂ
䛧䠔᭶㡭ቑຍ䛿Ṇ䜎䜛䚹ᅗᏊ࢖ࣔᩘࡢ᥎⛣䠄ᰘ⏣ (1994)䠖⸆⏝᳜≀᱂ᇵᢏ⾡䝣䜷䞊䝷䝮ㅮ₇せ᪨㞟䠄䛴䛟䜀䚸1991ᖺ7᭶䠅䚸pp1-6䚸ᨵኚ 䠅

─ 93 ─ཧ⪃㈨ᩱ

ᅗ䠎ᆅୗ㒊஝≀㔜䛾᥎⛣䠄ᰘ⏣ (1994)䠖⸆⏝᳜≀᱂ᇵᢏ⾡䝣䜷䞊䝷䝮ㅮ₇せ᪨㞟䠄䛴䛟䜀䚸1991ᖺ7᭶䠅䚸pp1-6䚸ᨵኚ 䠅 㻌ᆅୗ㒊䛿䠔᭶୰᪪䜎䛷䜖䜛䜔䛛䛻⫧኱䛧䛯ᚋ䠈䠕᭶ୖ᪪௨㝆ᛴ⃭䛻⫧኱䛧䚸䛣䛾䠍䞄᭶༙䡚䠎䞄᭶䛷஝≀㔜䛿ಸຍ䛩䜛䚹─ 94 ─ཧ⪃㈨ᩱ䠄᳜௜ࡅ᪉ἲ࡟ࡘ࠸࡚㸧㸧ᅗ㸱 ✀⌫ࡢᙧែ࡜኱ࡁࡉูࡢ᰿ⱼ㸦໭ぢ㎰ヨ㸪ᖺ㸧㻌 㻌 20䡚30䡃䛾✀䜲䝰䜢ᾘẘ䠄䝧䞁䝺䞊䝖䠅ᚋ䚸ⱆ䜢ୖ䛻ྥ䛡䛶⨨䛝䚸㍍䛟そᅵ䠄䠎cm⛬ᗘ䠅䛩䜛䚹
─ 95 ─ཧ⪃㈨ᩱ䠄᳜௜ࡅ᪉ἲ࡟ࡘ࠸࡚㸧㸧⾲㻌 ᳜௜䛡᫬ᮇ䛜⏕⫱཰㔞䛻ཬ䜌䛩ᙳ㡪
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⏕᰿ⱼ཰㔞䠄kg/10a䠅᳜௜䛡᫬ᮇ㻌
ⴌⱆ᫬ᮇ䠄᭶᪥䠅㻌⛅᳜䛘㻌᫓᳜䛘㻌 ⛅᳜䛘㻌 ᫓᳜䛘㻌 㻌 ⛅᳜䛘㻌 ᫓᳜䛘㻌 ᫓᳜䛘㻛⛅᳜䛘㻌㻌    

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  

 㻌 

䠄໭ぢ㎰ヨ䚸1988ᖺᨵኚ䠅⾲䠐㻌 ᱂᳜ᐦᗘ䛜᰿ⱼ཰㔞䛻ཬ䜌䛩ᙳ㡪㻌 䠄1979䡚1ϵ81ᖺ䛾ᖹᆒ䠅㻌 㻌 㻌 㻌 㻌 ᙧ㉁㻌
ᙧ㉁ 㻌 㻌 㻌 〇ရ᰿ⱼ㔜䠄kg/10a䠅㻌 㻌 㻌 㻌 㻌 ྠᕥ䛾␇ᖜ60cm x ᰴ㛫24cm༊ᑐẚ(%)
㻌 㻌 㻌 㻌 㻌 ᰴ㛫㻌
ᰴ㛫
␇ ᖜ
␇㻌
ᖜ㻌 㻌 㻌 㻌 㻌 㻌 㻌 16 cm 㻌

24 cm㻌 㻌

32 cm㻌 㻌

16 cm㻌 㻌

24 cm㻌 㻌

32 cm

㻌 40 㻌 cm

765

716

610

120

112

95

50㻌 cm

761

659

604

119

103

95

60 㻌 cm

686

639

496

107

100

78

䞉㻤㻘㻜㻜㻜䡚㻥㻘㻜㻜㻜ᰴ䠋㻝㻜䠽⛬ᗘ䛜ᐇ⏝ᛶ䛜㧗䛔䚹㻌䞉ᚲ䛪⛅᳜䛘䛩䜛䚹㻌─ 96 ─ཧ⪃㈨ᩱ䠄᪋⫧᪉ἲ࡟ࡘ࠸࡚㸧㸧(ᰘ⏣䜙 (1993)䠖
⏕⸆Ꮫ㞧ㄅ䚸
47 (1)䚸5-11.ᨵኚ䠅─ 97 ─ཧ⪃㈨ᩱ䠄᪋⫧᪉ἲ࡟ࡘ࠸࡚㸧㸧㻌㻌ヨ㦂༊ Dᙜ䛯䜚஝⇱཰㔞 NJD䠅
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DEF䛿␗䛺䜛➢ྕ㛫䛷༴㝤⋡䛷᭷ព䠄OVG 䠅(ᰘ⏣䜙 (1993)䠖⏕⸆Ꮫ㞧ㄅ䚸47 (1)5-11.)䠑᭶ᮇ䛾㏣⫧䛜᭱䜒ຠᯝⓗ䛷䛒䜛䛣䛸䛜ุ᫂䛧䠈㻌㻌㻤᭶ୖ᪪䛾᪋⫧䛿཰✭ᮇ䛜㻝㻜᭶ୖ䡚୰᪪䛸䛺䜛㐨໭ᆅ᪉㻌䛾᱂ᇵᙧែ䛷䛿䛭䛾ຠᯝ䛿ᑡ䛺䛔䛸⪃䛘䜙䜜䛯䚹㻌─ 98 ─ཧ⪃㈨ᩱ䠄཰✭ᚋ䛾ㄪ〇᪉ἲ䛻䛴䛔䛶䠅䠅㻌⾲㻤㻌 ஝⇱᪉ἲ䛜ရ㉁䛻ཬ䜌䛩ᙳ㡪
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㻌㻌

ㄪ〇᪉ἲ
㻌 ᅵ௜䛝䛾䜎䜎ᒇእ⮬↛஝⇱㻢㻝᪥㛫㻌㻌㻌㻌㻌㻌㻌㻌㻌㻌㻌㻌㻌㻌㻌㻌㻌㻌㻌㻌㻌㻌㻌㻌䊻 㢼஝⇱䠄㻡㻜䉝䠅㻞᪥㛫㻌㻌 ỈὙ䊻ᒇእ⮬↛஝⇱㻢㻝᪥㛫㻌㻌 㻌 㻌 㻌 㻌 㻌 㻌 㻌 㻌㻌㻌 㻌䊻 㢼஝⇱㻔㻡㻜䉝㻕㻞᪥㛫㻌㻌 ỈὙ䊻‫‮‬㏻䛧㻞㻜ศ㛫䊻ᒇእ⮬↛஝⇱㻢㻝᪥㛫㻌㻌㻌㻌㻌㻌㻌㻌㻌㻌㻌㻌㻌㻌㻌㻌㻌㻌㻌㻌㻌㻌㻌㻌䊻 㢼஝⇱䠄㻡㻜䉝䠅㻞᪥㛫㻌
㻌 ỈὙ䊻

㻌㻌

㻌㻌

㸨
ᕼ䜶䝍䝜䞊䝹䝅䝵⢾ 䝸䜾䝇䝏䝷䜲䝗
䜶䜻䝇
%/DW
%/DW
%/DW

㢼஝⇱㻔㻡㻜䉝㻕㻟᪥㛫㻌㻌 ỈὙ䊻෾⤖஝⇱㻌

46.7

36.0

0.46

46.4

34.4

0.46

13.6

3.7

0.41

18.0

6.1

0.39

15.5

4.6

0.18

1996ᖺ10᭶25᪥཰✭㻌䠄ጜᖏ䜙䠄2001䠅䚸㐨⾨◊ᡤሗ51ᕳ䠈13-17.ᨵኚ䠅䠆⾑ᾮจᅛ㜼ᐖάᛶ䠄㥑䛚⾑స⏝䠅䜢♧䛩ᡂศ䛾୍䛴䛸⪃䛘䜙䜜䛶䛔䜛䚹㻌ᕼ䜶䝍䝜䞊䝹䜶䜻䝇ྵ㔞䛿཰✭ᚋ䚸⮬↛஝⇱୰䛻ቑຍ䛩䜛䚹㻌䝸䜾䝇䝏䝷䜲䝗䠆䜒ྠᵝ䛾ഴྥ䜢♧䛩䚹㻌

─ 99 ─ཧ⪃㈨ᩱ䠄཰✭ᚋ䛾ㄪ〇᪉ἲ࡟ࡘ࠸࡚㸧㸧⾲㻌 ⮬↛஝⇱ᮇ㛫䛜ရ㉁䛻ཬ䜌䛩ᙳ㡪
㻌

㻌

㻌㻌

ᕼ䜶䝍䝜䞊䝹䜶䜻䝇䠄%/DW)ẕ䜲䝰㻌Ꮚ䜲䝰 㻌 㻌䝅䝵⢾䠄%/DW)ẕ䜲䝰㻌Ꮚ䜲䝰 㻌 䝸䜾䝇䝏䝷䜲䝗㻖㻌䠄%/DW)ẕ䜲䝰㻌Ꮚ䜲䝰 㻌 

0

1㐌㛫

2㐌㛫

3㐌㛫

4㐌㛫

6㐌㛫

14.9
16.3

32.1
35.4

36.4
39.7

38.9
43.2

41.7
44.9

40.9
44.6

5.8
6.4

23.5
26.0

29.1
32.5

31.8
36.0

33.8
36.8

33.7
36.8

0.24

0.38

0.48

0.38

0.38

0.48

0.29

0.44

0.46

0.40

0.41

0.48

2000ᖺ10᭶30᪥཰✭䚸ᅵ௜䛝䛾≧ែ䛷㢼஝⯋䛾Ჴୖ䛻ᡤᐃ䛾ᮇ㛫ᨺ⨨ᚋ䚸10ศ㛫⵨䛧䛯ᚋ䚸 65᪥㛫⮬↛஝⇱䛧䚸䛭䛾ᚋ䠈50Υ䛷3᪥㛫 㢼஝⇱䛧䛯䚹䠄ጜᖏ䜙䠄2008䠅་⸆ရ◊✲ 39ᕳ7ྕ䠈427-435.ᨵኚ䠅㸨⾑ᾮจᅛ㜼ᐖάᛶ㸦㥑࠾⾑స⏝㸧ࢆ♧ࡍᡂศࡢ୍ࡘ࡜⪃࠼ࡽࢀ࡚࠸ࡿࠋ

ᕼ䜶䝍䝜䞊䝹䜶䜻䝇ྵ㔞䛿཰✭ᚋ䛾⮬↛஝⇱୰䛻ቑຍ䛩䜛䚹㻌䝸䜾䝇䝏䝷䜲䝗䠆䜒ྠᵝ䛾ഴྥ䜢♧䛩䛸⪃䛘䜙䜜䜛䚹㻌─ 100 ─ཧ⪃㈨ᩱ䠄཰✭ᚋ䛾ㄪ〇᪉ἲ࡟ࡘ࠸࡚㸧㸧⾲㻌 ㄪ〇᮲௳䛜ရ㉁䛻ཬ䜌䛩ᙳ㡪
ㄪ〇᪉ἲ

㏻
ᖖ
⾜
䛖
‫‮‬
㏻
䛧
ฎ
⌮
ᗘ

㻌㻌

㻌㻌

ᕼ䜶䝍䝜䞊䝹䜶䜻䝇䝅䝵⢾ 䝸䜾䝇䝏䝷䜲䝗
%/DW
%/DW
%/DW

㢼஝⇱䠄㻡㻜䉝䠅㻡᪥㛫㻌⮬↛஝⇱䠄㻙㻝㻞ࠥ㻥䉝䠅㻢㻥᪥㛫䊻 㢼஝⇱䠄㻡㻜䉝䠅㻟᪥㛫㻌㻌㻌
‫‮‬㏻䛧ฎ⌮䠄㻠㻜䉝䠅㻞㻜ศ㛫㻌㻌㻌䊻⮬↛஝⇱䠄㻙㻝㻞ࠥ㻥䉝䠅㻢㻥᪥㛫䊻 㢼஝⇱䠄㻡㻜䉝䠅㻟᪥㛫㻌
‫‮‬㏻䛧ฎ⌮䠄㻠㻡䉝䠅㻞㻜ศ㛫㻌㻌㻌䊻⮬↛஝⇱䠄㻙㻝㻞ࠥ㻥䉝䠅㻢㻥᪥㛫䊻 㢼஝⇱䠄㻡㻜䉝䠅㻟᪥㛫㻌
‫‮‬㏻䛧ฎ⌮䠄㻡㻜䉝䠅㻞㻜ศ㛫㻌

23.9
47.3
㻌

12.5
38.2
㻌

0.33
0.39
㻌

37.4

28.0

0.34

11.6

1.7

0.24

㻌㻌䊻⮬↛஝⇱䠄㻙㻝㻞ࠥ㻥䉝䠅㻢㻥᪥㛫䊻㢼஝⇱䠄㻡㻜䉝䠅㻟᪥㛫㻌

13.7

3.5

0.23

㢼஝⇱䠄㻡㻜䉝䠅㻟᪥㛫㻌

20.7

4.1

0.29

㢼஝⇱䠄㻡㻜䉝䠅㻟᪥㛫㻌

24.3

4.7

0.24

㢼஝⇱䠄㻡㻜䉝䠅㻟᪥㛫㻌

21.4

4.8

0.23

㢼஝⇱䠄㻡㻜䉝䠅㻟᪥㛫㻌

17.9

5.6

0.23

㢼஝⇱䠄㻡㻜䉝䠅㻟᪥㛫㻌

15.2

5.9

0.24

㢼஝⇱䠄㻡㻜䉝䠅㻟᪥㛫㻌

14.5

5.2

0.26

㢼஝⇱䠄㻡㻜䉝䠅㻟᪥㛫㻌

14.0

5.2

0.26

‫‮‬㏻䛧ฎ⌮䠄㻡㻡䉝䠅㻞㻜ศ㛫㻌㻌㻌䊻⮬↛஝⇱䠄㻙㻝㻞ࠥ㻥䉝䠅㻢㻥᪥㛫䊻
‫‮‬㏻䛧ฎ⌮䠄㻢㻜䉝䠅㻞㻜ศ㛫㻌㻌㻌䊻⮬↛஝⇱䠄㻙㻝㻞ࠥ㻥䉝䠅㻢㻥᪥㛫䊻
‫‮‬㏻䛧ฎ⌮䠄㻢㻡䉝䠅㻞㻜ศ㛫㻌㻌㻌䊻⮬↛஝⇱䠄㻙㻝㻞ࠥ㻥䉝䠅㻢㻥᪥㛫䊻
‫‮‬㏻䛧ฎ⌮䠄㻣㻜䉝䠅㻞㻜ศ㛫㻌㻌㻌䊻⮬↛஝⇱䠄㻙㻝㻞ࠥ㻥䉝䠅㻢㻥᪥㛫䊻
‫‮‬㏻䛧ฎ⌮䠄㻣㻡䉝䠅㻞㻜ศ㛫㻌㻌㻌䊻⮬↛஝⇱䠄㻙㻝㻞ࠥ㻥䉝䠅㻢㻥᪥㛫䊻
‫‮‬㏻䛧ฎ⌮䠄㻤㻜䉝䠅㻞㻜ศ㛫㻌㻌㻌䊻⮬↛஝⇱䠄㻙㻝㻞ࠥ㻥䉝䠅㻢㻥᪥㛫䊻
‫‮‬㏻䛧ฎ⌮䠄㻤㻡䉝䠅㻞㻜ศ㛫㻌㻌㻌䊻⮬↛஝⇱䠄㻙㻝㻞ࠥ㻥䉝䠅㻢㻥᪥㛫䊻

2000ᖺ10᭶30᪥཰✭䚸ỈὙ䛧䛯Ꮚ䜲䝰䜢ᮦᩱ䛻䛧䛯䚹䠄ጜᖏ䜙䠄2007䠅䚸་⸆ရ◊✲ 38ᕳ9ྕ䠈435-441.ᨵኚ䠅ᕼ࢚ࢱࣀ࣮࢚ࣝ࢟ࢫྵ㔞ࡣ཰✭᫬ᮇࡼࡾࡶࠊ཰✭ᚋࡢ஝⇱࣭ㄪ〇᮲௳࡛኱ࡁࡃኚ໬ࡍࡿࠋ
ࣜࢢࢫࢳࣛ࢖ࢻࡶ⮬↛஝⇱ᮇ㛫࡟ቑຍࡍࡿഴྥࢆ♧ࡍࠋ‫‮‬㏻ࡋ࡟ࡼࡾ᫂ࡽ࠿࡟పୗࡍࡿࠋ
─ 101 ─䝭䝅䝬䝃䜲䝁᱂᱂ᇵ䛻䛴䛴䛔䛶䝭䝅䝬䝃䜲䝁
⏕⸆ྡ䠖䝃䜲䝁䠄ᰘ⬌䠅ᇶཎ᳜≀䠖Bupleurum falcatum L. 䠄䝉䝸⛉䠅ཎ⏘ᆅ䠖᪥ᮏ
฼⏝㒊఩䠖᰿
⸆ຠ䠖ゎ⇕䚸ゎẘ䚸㙠③䚸⫢ᶵ⬟ᨵၿ₎᪉ฎ᪉䠖ᑠᰘ⬌‫‮‬䚸኱ᰘ⬌‫‮‬䚸⿵୰┈Ẽ‫‮‬䚸ຍ࿡ゎ㻌 㻌 㻌 㻌 㻌 㻌 ẘ‫‮‬䛺䛹䚸୍⯡⏝₎᪉〇๣294ฎ᪉䛾ෆ䚸㻌 㻌 㻌 㻌 㻌 㻌 43ฎ᪉䛻㓄ྜ䚹⏕⏘ᆅ䠖㧗▱䚸ឡ፾䚸⇃ᮏ䚸㟼ᒸ䚸⩌㤿䛺䛹⏕⸆෗┿䠖་⸆ᇶ┙೺ᰤ◊䞉⸆⏝᳜≀⥲ྜ᝟ሗ䝕䞊䝍䝧䞊䝇䜘䜚─ 105 ─䝃䜲䝁䠄ᰘ⬌䠅䛾つ᱁䠄䠦䠬17䠅䝃䜲䝁
Bupleurum Root
BUPLEURI RADIXᰘ⬌㻌 ᮏရ䛿䝭䝅䝬䝃䜲䝁Bupleurum falcatum Linné(Umbelliferae)䛾᰿䛷䛒䜛.
㻌 ᮏရ䛿ᐃ㔞䛩䜛䛸䛝䠈᥮⟬䛧䛯⏕⸆䛾஝⇱≀䛻ᑐ䛧䠈⥲䝃ポニ
䝙䞁(䝃䜲䝁䝃䝫䝙䞁aཬ䜃䝃䜲䝁䝃䝫䝙䞁d) 0.35%௨
ୖ 䜢ྵ䜐.
⣧ᗘヨ㦂㻌 (1)㻌 ⱼཬ䜃ⴥ㻌 ᮏရ䛿䠈␗≀䚾5.01䚿䛻ᚑ䛔ヨ㦂䜢⾜䛖䛸䛝䠈ⱼཬ䜃ⴥ10.0%௨ୖ䜢ྵ䜎䛺䛔.
㻌 (2)㻌 㔜㔠ᒓ䚾1.07䚿㻌 ᮏရ䛾⢊ᮎ3.0 g䜢䛸䜚䠈➨3ἲ䛻䜘䜚᧯స䛧䠈ヨ㦂䜢⾜䛖.ẚ㍑ᾮ䛻䛿㖄ᶆ‽ᾮ3.0 mL䜢ຍ䛘䜛(10 ppm௨ୗ).
㻌 (3)㻌 䝠⣲䚾1.11䚿㻌 ᮏရ䛾⢊ᮎ0.40 g䜢䛸䜚䠈➨4ἲ䛻䜘䜚᳨ᾮ䜢ㄪ〇䛧䠈ヨ㦂䜢⾜䛖(5 ppm௨ୗ).
㻌 (4)㻌 ␗≀䚾5.01䚿㻌 ᮏရ䛿ⱼཬ䜃ⴥ௨እ䛾␗≀1.0%௨ୖ
䜢ྵ䜎䛺䛔.
஝⇱ῶ㔞䚾5.01䚿㻌 12.5%௨ୗ(6᫬㛫).
⅊ศ䚾5.01䚿㻌 6.5%௨ୗ.
㓟୙⁐ᛶ⅊ศ䚾5.01䚿㻌 2.0%௨ୗ.
䜶䜻䝇ྵ㔞䚾5.01䚿㻌 ᕼ䜶䝍䝜䞊䝹䜶䜻䝇 11.0%௨ୖ.
㈓ἲ㻌 ᐜჾ㻌 ᐦ㛢ᐜჾ.

─ 106 ─䝃䜲䝁䠄ᰘ⬌䠅䛾つ᱁䠄䠦䠬17䠅⏕⸆䛾ᛶ≧㻌㻌 ᮏရ䛿⣽㛗䛔෇㗹ᙧࠥ෇ᰕᙧ䜢࿊䛧䠈༢୍ཪ䛿ศᯞ䛧䠈㛗䛥10 ࠥ20 cm䠈ᚄ0.5 ࠥ1.5 cm䠈᰿㢌䛻䛿ⱼ䛾ᇶ㒊䜢௜䛡䛶䛔䜛䛣䛸䛜䛒䜛.እ㠃䛿ῐ〓Ⰽࠥ〓Ⰽ䛷䠈῝䛔䛧䜟䛜䛒䜛䜒䛾䜒䛒䜛.ᢡ䜚䜔䛩䛟䠈ᢡ㠃䛿䜔䜔⧄⥔ᛶ䛷䛒䜛.
㻌 ᮏရ䛿≉␗䛺䛻䛚䛔䛜䛒䜚䠈࿡䛿ഹ䛛䛻ⱞ䛔.
㻌 ᮏရ䛾ᶓษ∦䜢㙾᳨䚾5.01䚿䛩䜛䛸䛝䠈⓶㒊䛾ཌ䛥䛿༙ᚄ 䛾1/3 ࠥ1/2䛷䠈⓶㒊䛻䛿䛧䜀䛧䜀᥋⥺᪉ྥ䛻㛗䛔⿣䛡┠䛜䛒䜚䠈ᚄ15 ࠥ35 ʅŵ䛾Ἔ㐨䛜䜔䜔ከᩘᩓᅾ䛩䜛.ᮌ㒊䛻䛿㐨⟶䛜ᨺᑕ≧ཪ䛿䜋䜌㝵ẁ≧䛻㓄ิ䛧䠈䛸䛣䜝䛹䛣䜝䛻⧄⥔⩌䛜䛒䜛.᰿㢌㒊䛾㧊䛻䛿⓶㒊䛸ྠᵝ䛾Ἔ㐨䛜䛒䜛.ᰂ⣽⬊୰䛻䛿䛷䜣䜇䜣⢏ཬ䜃Ἔ⁲䜢ㄆ䜑䜛.䛷䜣䜇䜣⢏䛿༢⢏ཪ䛿」⢏䛷䠈༢⢏䛾ᚄ䛿2 ࠥ10 ʅŵ䛷䛒䜛.

─ 107 ─⏕⸆䝃䜲䝁䛾ရ㉁䘆࿴₎⸆䛾Ⰻྰ㚷ูἲཬㄪ〇᪉䠄୍Ⰽ┤ኴ㑻⦅㻌 ྤ㬅ᇽ᭩ᗑ䠅㻌㻌 䘆㰡䛾ᑿ䛾䜘䛖䛺ᙧ≧䜢䛧䛶䛔䜛⣽㛗᰿䚹㻌 䘆⓶䛜㉥㯮Ⰽ䛷ෆ㒊䛜ῐ〓Ⰽ䛷䚸࿡䛾ⱞ䛔ᚤ䛻㤶Ẽ䛾䛒䜛䜒䛾䛜䜘䛔䚹㻌 䘆䛺䜛䜉䛟ศᒱ䛧䛶䛔䛺䛔┿┤䛺᰿䛷䚸ෆ㒊䛾Ⰽ䛾ῐ䛔ᮙ䛱䛶䛔䛺䛔ኴ䛔䜒䛾䜢㑅䜆䚹㻌 䘆Ἔ䛟䛥䛔䜒䛾䜔⒓䛫䛯ᑠ䛥䛔䜒䛾䛿Ⰻ䛟䛺䛔䚹䘆⸆⏝᳜≀᱂ᇵ᥇཰ἲ䠄ส⡿㐩ኵ䚸ⱝᯘᴿᅄ
㑻ඹⴭ㻌 ༡ᲄ᭩ᗑ䠅㻌㻌 䘆᰿㒊䛜⫧኱䛧䛯䜒䛾䛷䚸᰿䛾䛧䜎䜚Ⰻ䛟ษ䜚ཱྀ䛾ⓑ䛔䜒䛾䛜Ⰻရ䚹㻌 䘆ኴ䛟䛸䜒Ὕ䛾䛒䜛䜒䛾䛿୙Ⰻရ䚹

─ 108 ─䝭䝅䝬䝃䜲䝁᱂᱂ᇵ䛾ᐇ㝿䝭䝅䝬䝃䜲䝁᱂ᇵ㐺ᆅ䞉Ẽೃ䛿 ᬮ䛺ᆅᇦ䛻㐺䛩䜛䚹䞉ᅵ㉁䛿⪔ᅵ䛜䜔䜔῝䛟䚸⫧Ỻ䛺ተᅵࠥᇰᅵ䛻㐺䛩䜛䚹䞉᪥↷୪䜃䛻᤼ỈⰋዲ䛺ᅵᆅ䛻㐺䛩䜛䚹᪥㝜䜔᤼Ỉ୙Ⰻᆅ䛷䛾᱂ᇵ䛿㑊䛡䜛䚹䝭䝅䝬䝃䜲䝁᱂ᇵ䛾せⅬ䚸᳜≀䛾≉㉁1䠅⦾Ṫ䛿✀Ꮚ䛻䜘䜛䚹
2䠅᰿䛾⏕⏘䜢┠ⓗ䛸䛩䜛᱂ᇵᖺᩘ䛿䠍ᖺཪ䛿䠎ᖺ䚹᥇✀䛿䠎ᖺ⏕௨ୖ䛾ᰴ䛛䜙⾜䛖䚹3䠅᧛✀䛛䜙Ⓨⱆ䜎䛷⣙䠍䞄᭶䜢せ䛧䚸ึᮇ⏕⫱䛿⦆៏䛷䛒䜛䚹⏕⫱ึᮇ䛾㞧ⲡ㜵㝖䛻ດ䜑䚸ⱑ❧䛱ᩘ䜔ᰴᩘ䜢☜ಖ䛩䜛䚹
4䠅⏕⫱ᮇ㛫୰䚸䠎䡚䠏ᅇ䚸ᆅୖ㒊䜢᦬ⰺ䛧䚸᰿䛾ᡂ㛗䜢ಁ䛩䛸䛸䜒䛻ᰴ䛾ಽఅ㜵Ṇ䜔✀Ꮚ䛾඘ᐇ䜢ᅗ䜛䚹─ 111 ─‫ڹࠉࠉࠉڹ‬᧛ࠉ✀⑓ ᐖ⹸㜵 㝖

㛫ᘬ ࡁ

୍ᖺ ┠

஧ᖺ ┠

‫ࠉࠉࠉࠉڹ‬‫ڹࠉࠉࠉࠉࠉࠉࠉڹ‬
᥇ࠉ✀
཰ࠉ ࠉ✭

‫ڹࠉࠉࠉࠉࠉࠉࠉڹ‬཰ࠉ ࠉ✭⏕⫱┦࡜సᴗ

─ 112 ─సᴗࡢෆᐜ‫ۼ‬㛫ᘬࡁ㸦㹼ⴥᮇ㸧ࠉࠉᰴ㛫ࠉFP㛫㝸㸦༓㫽≧㸧‫ۼ‬㝖ⲡ๣ᩓᕸ㸦᧛✀ᚋ㹼ฟⱆ๓ࠊⓎⱆᮇ㸧ࠉࠉࢦ㸫ࢦ㸫ࢧࣥங๣ࠉPODࠉࠉࢦ㸫ࢦ㸫ࢧࣥ⣽⢏๣)ࠉ㹼NJD‫✀᧛ۼ‬ࠉࠉ᮲㛫ࠉ㹼FP࡟᮲᧛‫✀᧛ۼ‬㔞㸦Dᙜࡓࡾ㸧ࠉࠉ㹼J䛂⸆⏝᳜≀㻌 ᱂ᇵ䛸ရ㉁ホ౯䛃㻌 Part 1 㻔⸆஦᪥ሗ♫䚸1992ᖺ㻕㻌ᨵኚ㻌‫ۼ‬᥇✀ࠉࠉ㸰ᖺ⏕ᰴ࠿ࡽ✀Ꮚࢆ᥇ࡿࠋ

‫཰ۼ‬㔞㸦Dᙜࡓࡾ஝⇱㔜㔞㸧ࠉࠉ㸯ᖺ⏕ࠉ㹼NJࠊ㸰ᖺ⏕ࠉ㹼NJ‫ۼ‬ㄪ〇ࠉࠉᆅୖ㒊ࢆᆅ㝿࠿ࡽษࡾⴠ࡜ࡍࠋ
ࠉࠉὙίࡋࡓ᰿ࡀ༙஝⇱ࡢ᫬࡟ࠊࣄࢤ᰿ࢆྲྀࡾ㝖ࡃࠋࠉࠉᙧࢆᩚ࠼ࡿࠋ
ࠉࠉỈศྵ㔞㸣⛬ᗘࡲ࡛஝⇱ࡍࡿࠋ‫✭཰ۼ‬ࠉࠉ㝆㟖ᚋࠊᆅୖ㒊ࡀᯤṚࡋࡓ᫬ᮇ࡟⾜࠺ࠋࠉࠉᆅୖ㒊ࢆFP⛬ᗘṧࡋ࡚สࡾྲྀࡾࠊ᰿ࢆ᥀ࡾ㉳ࡇࡍࠋࠉࠉ᰿ࢆⰋࡃỈὙ࠸ࡋࠊᅵ◁ࢆⴠ࡜ࡍࠋ

㏣
ࠉ ⫧
‫ۼ‬㏣⫧
ࠉ㸯ᖺ┠
ࠉࠉ㸯ᅇ┠㸦୰㹼ୗ㸧
ࠉࠉࠉ1.໬ᡂ㸦㸧㸸㹼NJࠉࠉ㸰ᅇ┠㸦ୖ㹼୰㸧
ࠉࠉࠉ1.໬ᡂ㸦㸧㸸㹼NJࠉ㸰ᖺ┠ࠉࠉ㸯ᅇ┠㸦ୗ㹼ୖ㸧ࠉࠉࠉⱞᅵ▼⅊㸸㹼NJ
ࠉࠉࠉ⳯✀Ἔ⢑㸸㹼NJࠉࠉࠉ㭜ࠉࠉ⣅㸸㹼NJ
ࠉࠉࠉ໬ᡂ⫧ᩱ㸦㸧㸸㹼NJࠉࠉ㸰ᅇ┠㸦ୗ㹼ୖ㸧
ࠉࠉࠉ1.໬ᡂ㸦㸧㸸㹼NJ୰ࠉ ⪔‫✀ۼ‬Ꮚணᥐ
ࠉࠉὶỈ᫬㛫ᾐₕⓎࠉ ⱆ‫ⰺ᦬ۼ‬㸦╔ⷣᮇ㸧ࠉࠉᆅୖ㒊ࡀ⦾ⱱࡋࡓ᫬
ࠉࠉᆅୖ㒊㹼FP࡛ษ㝖ࠉࠉ᦬ⰺᮇ㛫୰࡟㹼ᅇᐇ᪋㏣ࠉ ⫧‫⑓ۼ‬ᐖ⹸㜵㝖
ࠉࠉⅣࠉࡑࠉ⑓㸸ᱵ㞵ᮇࠊ⛅㞵ᮇࠉࠉ᰿ࠉᮙࠉ⑓㸸⏕⫱ᚋᮇࠉࠉ࢔ࣈ࣒ࣛࢩ㸸⏕⫱ᮇ඲⯡㝖ࠉ ⲡ‫ۼ‬ᇶ⫧㸦Dᙜࡓࡾ㸧ࠉࠉሁࠉࠉ⫧㸸㹼NJ
ࠉࠉⱞᅵ▼⅊㸸㹼NJ
ࠉࠉ໬ᡂ⫧ᩱ㸦㸧㸸㹼NJ‫ۑࠉࠉࠉࠉࠉࠉࠉࠉࠉࠉࠉࠉࠉۑ‬㛤ࠉⰼࠉᮇ‫ڹࠉࠉࠉࠉࠉࠉڹ‬
᦬ࠉࠉⰺ
㏣ࠉ⫧

‫ۑࠉࠉࠉࠉࠉࠉࠉࠉࠉࠉۑ‬㛤ࠉⰼࠉᮇ‫ڹࠉࠉࠉࠉࠉࠉڹ‬
᦬ࠉࠉⰺ
㏣ࠉ⫧

᭶












᪪ ୖ ୰ ୗ ୖ ୰ ୗ ୖ ୰ ୗ ୖ ୰ ୗ ୖ ୰ ୗ ୖ ୰ ୗ ୖ ୰ ୗ ୖ ୰ ୗ ୖ ୰ ୗ ୖ ୰ ୗ ୖ ୰ ୗୖ ୰ ୗ䝭䝅䝬䝃䜲䝁䛾᱂ᇵᬺ㏣
ࠉ ⫧─ 113 ─

2017.1.11⌧ᅾ䝁䝔䝒䝣䝻䜰䝤䝹

㻰㻙㻰๣䠄ྛ✀䠅䝖䝑䝥䝆䞁㻹Ỉ࿴๣䝎䝁䝙䞊䝹㻝㻜㻜㻜䜰䝭䝇䝍䞊㻞㻜䝣䝻䜰䝤䝹 Ⅳ⑋⑓䝂䞊䝂䞊䝃䞁ங๣㻟㻜 ୍ᖺ⏕㞧ⲡ䝂䞊䝂䞊䝃䞁⣽⢏๣㻲

ẅ⹸๣

ẅ⹸๣

ẅ⳦๣

ẅ⳦๣

ẅ⳦๣

㝖ⲡ๣

㝖ⲡ๣

㻢㻌㼗㼓㻛㻝㻜㼍
㻞㻜㻜㻜ಸ

㻝㻜㻜㻜ಸ

㻝㻜㻜㻜ಸ
ⴌⱆ⑓

཰✭㻟㻜᪥๓䜎䛷཰✭㻟㻜᪥๓䜎䛷
䠍ᅇ

䠏ᅇ௨ෆ

䠏ᅇ௨ෆ

一ᖺ⏕㞧ⲡ

୍ᖺ⏕㞧ⲡ

Ⅳ⑋⑓

Ⅳ⑋⑓

㻟㻜㻜䡚㻡㻜㻜㻌㼙㻸㻛㻝㻜㼍㻟䡚㻡㻌㼗㼓㻛㻝㻜㼍㻟㻜㻜㻌㼙㻸㻛㻝㻜㼍

㻞㻜㻜㻜ಸ

㻤㻜㻜ಸ

㻝㻜㻜㻜ಸ

཰✭䠓᪥๓䜎䛷

᧛✀ᚋ䡚Ⓨⱆᮇ

᧛✀ᚋฟⱆ๓

཰✭㻞㻝᪥๓䜎䛷཰✭㻟㻜᪥๓䜎䛷཰✭㻟㻜᪥๓䜎䛷

䠏ᅇ௨ෆ

䠍ᅇ

䠍ᅇ

䠐ᅇ௨ෆ

䠏ᅇ௨ෆ

䠎ᅇ௨ෆ

䝝䝇䝰䞁䝶䝖䜴
཰✭㻞㻝᪥๓䜎䛷 䠎ᅇ௨ෆ䝛䜾䝃䝺䞉䝛䝁䝤䝉䞁㻝㻡䡚㻞㻜㻌㻸㻛㻝㻜㼍 స௜䛾㻝㻜䡚㻝㻡᪥๓䜎䛷 䠍ᅇ䝏䝳䜴䚸䝁䜺䝛䝮䝅㢮ᗂ⹸䝛䜻䝸䝮䝅㢮

䛭䛾௚䚸䛂㔝⳯㢮䛃䛻㐺⏝䛾䛒䜛㎰⸆㝖ⲡ๣䚷䚷䚷㻌䝞䝇䝍ᾮ๣䝣䜷䞊䝇⢏๣

ẅ⹸๣䜰䝤䝷䝮䝅㢮

䜰䝗䝬䜲䜰䞊㢛⢏Ỉ࿴๣ẅ⹸๣䜰䝤䝷䝮䝅㢮

䜸䝹䝖䝷䞁Ỉ࿴๣ẅ⹸๣඲㠃ᅵተᩓᕸ

඲㠃ᅵተᩓᕸ

ᩓᕸ

ᩓᕸ

ᩓᕸ

ᩓᕸ
඲㠃ฎ⌮
స᮲ฎ⌮

ᰴඖᩓᕸ

ᩓᕸ

ᩓᕸ

㎰⸆䛾✀㢮䚷䚷䚷䚷䚷㎰⸆ྡ䚷䚷䚷䚷䚷㐺⏝⑓ᐖ⹸䞉㞧ⲡ䚷䚷䚷䚷䚷ᕼ㔘ಸ⋡䚷䚷䚷䚷䚷౑⏝᫬ᮇ䚷䚷䚷䚷౑⏝ᅇᩘ䚷䚷䚷䚷౑⏝᪉ἲ䝭䝅䝬䝃䜲䝁䛻㐺⏝䛾䛒䜛㎰⸆౛඲㠃ᅵተᩓ✀Ꮚ䞉᧛✀
䛔䜝䛔䜝䛺᧛✀ἲ

5cm

䝭䝅䝬䝃䜲䝁䛾✀Ꮚ

20 cm

90ࠥ100 cm

15ࠥ20 cm⦾ Ṫ ἲ 㻌 ✀Ꮚ⦾Ṫ䠄100⢏㔜䠖⣙150 mg䠅᧛✀᫬ᮇ㻌 㛵ᮾᆅ᪉㻌 3᭶୰᪪ࠥ4᭶ୖ᪪㻌 㻌 㻌 㻌 㻌 㻌 㻌 䠄Ⓨⱆ㐺 20Υ๓ᚋ䠅㻌 㻌 㻌 㻌 㻌 㻌 㻌 ᫓ඛ䛻㝆Ỉ㔞䛜ᑡ䛺䛔ᆅ᪉䛷䛿㻌 㻌 㻌 㻌 㻌 㻌 㻌 ⛅᧛䛝䚹᧛ ✀ 㔞㻌 800 gࠥ1 kg/10 a㻌 㻌 㻌 㻌 㻌 㻌 㻌 ᧛✀㔞䛿500 g䛟䜙䛔䛷䜒䜘䛔䛜䚸㻌 㻌 㻌 㻌 㻌 㻌 㻌 ከ䜑䛜↓㞴䛷䛒䜛䚹᧛✀᪉ἲ㻌 15ࠥ20 cm䛾᧛䛝ᗋ䛻ᩓ᧛䚸1᮲㻌 㻌 㻌 㻌 㻌 㻌 㻌 ཪ䛿2᮲䛾᧛✀ᶵ䜢⏝䛔䛶┤᧛䚸㻌 㻌 㻌 㻌 㻌 㻌 㻌 ᗋ᧛䛝䛺䛹䚹
─ 114 ─

᪋㻌 ⫧
㻌

ᇶ⫧

㏣⫧

䠄10 aᙜ䛯䜚 䠅ሁ⫧㻌
1,000ࠥ2,000 kgⱞᅵ▼⅊㻌㻌 50ࠥ100 kg໬ᡂ⫧ᩱ䠄8-8-8䠅㻌 㻌 25ࠥ30 kg㻌㻌 1ᅇ┠䠄6/୰ࠥୗ䠅㻌 㻌 NK໬ᡂ䠄17-0-17䠅㻌 㻌㻌 㻌 㻌 㻌 㻌 㻌 㻌 12ࠥ15 kg㻌 2ᅇ┠䠄9/ୖࠥ୰䠅㻌 㻌 NK໬ᡂ䠄17-0-17䠅㻌 㻌 㻌㻌 㻌 㻌 㻌 㻌 㻌 㻌 12ࠥ15 kg䛂⸆⏝᳜≀㻌 ᱂ᇵ䛸ရ㉁ホ౯䛃㻌 Part 1 (⸆஦᪥ሗ♫䚸1992ᖺ) ᨵኚᅵተ䛾✀㢮䚸๓స䛾≧ἣ䛻䜘䛳䛶␗䛺䜛䛾䛷䛒䛟䜎䛷୍౛䛷䛒䜛䚹䞉䠎ᖺ┠䛾㏣⫧䛿䠍ᖺ┠䛻‽䛨䛶⾜䛖䚹䞉䝭䝅䝬䝃䜲䝁䛾ึᮇ⏕⫱䛿⦆៏䛺䛯䜑䚸ᇶ⫧䛿⦆⾜ᛶ⫧ᩱ䜔᭷ᶵ㉁⫧ᩱ䛜ᮃ䜎䛧䛔䚹䞉໬ᡂ⫧ᩱ䛿᰿䛾ᡂ㛗䜢ಁ㐍䛩䜛䛜䚸᰿䛜◳䛟䛺䜛ഴྥ䛜䛒䜛䛯䜑䚸᭷ᶵ㉁⫧ᩱ䛾᪋⏝䛻ᚰ䛜䛡䜛䚹
─ 115 ─

㛫ᘬ䛝

㛫ᘬ䛝
䛝๓

Ⓨⱆ䠖᧛✀ᚋ䚸Ꮚⴥ䛾ฟ⌧䜎䛷䠍䞄᭶⛬ᗘ䜢せ䛩䜛䚹䝭䝅䝬䝃䜲䝁䛾ึᮇ⏕⫱䛿⦆៏䛷䚸㞧ⲡ䛻㈇䛡䛶䛧䜎䛖䛯䜑䚸᧛✀ᚋ䛾㝖ⲡ๣䛾ᩓᕸ䛿㞧ⲡ㜵㝖䛻᭷ຠ䛷䛒䜛䚹㛫ᘬ䛝ᚋ䠖1ᖺ⏕᱂ᇵ䛷䛿ᰴ㛫䜢༑ศ䛻䛸䜚䚸㛫ᘬ䛟䚹
2ᖺ⏕᱂ᇵ䛷䛿ᐦ䛺⟠ᡤ䜢㛫ᘬ䛝䚸䜔䜔ᐦ᳜䛸䛩䜛䚹
─ 116 ─1ᖺ⏕ᰴ䛾⏕⫱䠒᭶ୗ᪪䚸ᢳⱏጞ䜎䜚䠓᭶୰᪪䚸㛤ⰼጞ䜎䜚䠔᭶ୖ᪪䚸᦬ⰺ┤ᚋј᦬ⰺ䛺䛧䚸䠕᭶ୖ᪪12᭶䚸཰✭ᮇ཰✭๓䛻ᆅୖ㒊䜢ษ㝖䛩䜛䚹

─ 117 ─᦬㻌 ⰺ᦬ⰺ๓䠄2ᖺ⏕ᰴ䚸1ᅇ┠6᭶ୗ᪪䠅᦬ⰺ䠄ᆅୖ㒊䜢ษ㝖䠅᦬ⰺᚋ
䠄50䠿䡉䛾㧗䛥䛷ษ㝖䠅᦬ⰺ䠖᰿䛾ᡂ㛗䜢ಁ䛩䛯䜑䚸⏕⫱ᮇ㛫୰䛻ᆅୖ㒊䜢2ࠥ3ᅇษ㝖䛩䜛䚹
1ᅇ┠䠄╔ⷣᮇࠥ㛤ⰼึᮇ䠅䚸2ᅇ┠䠄㛤ⰼᮇ䠅䚸3ᅇ┠䠄✀Ꮚᡂ⇍ᮇ䚸1ᖺ⏕ᰴ䠅
䘆3ᅇ┠䛿1ᖺ⏕ᰴ䜢ᑐ㇟䛻⾜䛔䚸✀Ꮚ䛾ⴠୗ䜢㜵䛠䚹2ᖺ⏕ᰴ䛿3ᅇ┠䛾᦬ⰺ䜢⾜䜟䛪䚸᥇✀䜢⾜䛖䚹
䘆2ᅇ┠䛾᦬ⰺ䛿䚸1ᅇ┠䛾ษ㝖㒊఩䛾10ࠥ20cmୖ㒊䜢ษ㝖䛩䜛䛸䜘䛔䚹⏕⫱䜔᥇✀㔞䛻᭷ຠ䛷䛒䜛䚹
─ 118 ─⑓ᐖ⹸㜵㝖
Ⅳ⑋⑓䠄ᆅୖ㒊䠅᰿ᮙ⑓䠄᰿䠅

᫛࿴61ࠥ62ᖺ䛻඲ᅜⓗ䛻኱Ⓨ⏕Colletotrichum sp.
Alternaria sp. 䛺䛹᰿᰿ᮙ⑓Phoma terrestris
Phomopsis sp.
Fusarium oxysporum
䛺䛹䛾」ྜឤᰁ
─ 119 ─཰㻌 ✭཰✭ᮇ䠖12᭶ࠥ1᭶㝆㟖ᚋ䚸ᆅୖ㒊䛜ᯤṚ䛧䛯ᚋ䚸ᅵ䛜෾⤖䛩䜛๓䚹ᆅୖ㒊䜢ส䜚ྲྀ䜚䚸᰿䜢㘵䜔䝇䝁䝑䝥ཪ䛿ᶵᲔ䛷᥀䜚ྲྀ䜚䚸Ỉ䛷Ⰻ䛟Ὑ䛔䚸ᅵ◁䜢ⴠ䛸䛩䚹㻌 ་⸆ᇶ┙೺ᰤ◊䞉⟃⟃Ἴ◊✲㒊䛻䛚䛡䜛཰཰✭㢼ᬒ䠄1990ᖺ䠅1ᖺ⏕᰿─ 120 ─

2ᖺ⏕᰿

᰿䛾ㄪ〇
ỈὙ䛧䛯᰿䛻ṧ䛳䛯ᆅୖ㒊䜢ᆅ㝿䛛䜙ษ䜚ⴠ䛸䛩䚹䝠䝀᰿䜢ྲྀ䜚㝖䛟䠄༙஝⇱䛾᫬䛻⾜䛖䠅䚹᰿䛾஝⇱䛿▷ᮇ㛫䛻⾜䛔䚸ಖᏑ䛩䜛䚹㻌⟃Ἴ◊✲㒊䛻䛚䛡䜛᰿䛾ㄪ〇㢼ᬒỈὙ䛧䛯᰿䜢㝧஝䛧䚸᰿䛜⏕஝䛝䛾᫬䛻ᡭ䛾ᖹ䛷ᥣ䜣䛷䚸䝠䝀᰿䜢ⴠ䛸䛧䚸᰿䜢ㄪ〇䛩䜛䚹

⏕⸆䛸䛸䛧䛶ㄪ〇䛥䛥䜜䛯᰿⏕⸆
─ 121 ─཰㻌 㔞ᖹᆒ཰㔞䠄஝⇱᰿䠅㻌 20ࠥ50 kg/10a 䠄1ᖺ⏕䠅
50ࠥ80 kg/10a 䠄2ᖺ⏕䠅㻌 ཰㔞せᅉ㻌 䘆ᰴᩘ䛾☜ಖ㻌 㻌㻌 ஝⇱᰿㔜1ᮏ=1 g䚸3୓ᮏ/10 a㻌㻌㻌㻌㻌㻌㻌㻌㻌㻌㻌㻌㻌㻌㻌㻌㻌㻌 㻌 㻌 㻌 㻌 㻌 㻌 㻌 㻌 㻌 㻌 㻌 ཰㔞30 kg/10 a㻌 䘆1ᮏᙜ䛯䜚᰿㔜䛾ቑຍ㻌 㻌 㻌 㻌 㻌 㻌 㻌 㻌 㻌 㻌 㻌 㻌 㛫ᘬ䛝䚸㏣⫧䛺䛹─ 122 ─᥇✀䛸✀Ꮚ䛾ㄪ〇䞉᥇᥇㻌 ✀䠖䠎ᖺ⏕௨ୖ䛾ᰴ䛛䜙᥇✀䛩䜛䚹䞉᥇᥇✀ἲ䠖✀Ꮚ䛜඘ᐇ䛧䛶䛝䛯䜙䠄✀Ꮚ䛾୍㒊䛜㯮Ⰽ໬䠅䚸ᰴ䛾ᆅ㝿䠑䡚10 cm䛾䛸䛣䜝䛷ษ㝖䛧䚸㞵Ỉ䛾ᙜ䛯䜙䛺䛔䛸䛣䜝䛷஝䛛䛧䚸✀Ꮚ䜢ᚋ⇍䛥䛫䜛䚹ส䜚ྲྀ䜚䛜㐜䛟䛺䜛䛸✀Ꮚ䛜⬺⢏䛩䜛䛯䜑䚸᪩䜑䛻ส䜚ྲྀ䜛䚹䞉ㄪㄪ㻌 〇䠖ᰴ䛜஝⇱䛧䛯䜙䚸✀Ꮚ䜢ⴠ䛸䛧䚸ỈὙ䛧䛶ỿ䜣䛰✀Ꮚ䜢㞟䜑䚸㏿䜔䛛䛻஝⇱䛥䛫䜛䚹䞉ಖಖ㻌 Ꮡ䠖஝⇱䛧䛯✀Ꮚ䜢ᐦᑒ䛧䚸෭ⶶᗜෆ➼ప䛷ಖᏑ䛩䜛䚹㻌

䠄1䠅

ୗ

䠄2䠅

⏕⫱ᮇ䠄9.14䠅䠄3䠅
᥇✀ᮇ䠄11.21䠅

᦬ⰺ䛧䛯᥇✀⏝䠎ᖺ⏕ᰴ䠖ᡭ๓䛛䜙䠎ᅇ᦬ⰺ༊䠄50-50䠿䡉䛷᦬ⰺ䚸5070䠿䡉䛷᦬ⰺ䠅ཬ䜃䠍ᅇ᦬ⰺ༊─ 123 ─✀Ꮚ䛾ㄪ〇䠖஝⇱䛥䛫䛯ᆅୖ㒊䠄1䠅䛛䜙✀Ꮚ䜢ⴠ䛸䛧䚸⠠䛷኱䛝䛺䝂䝭䜢ྲྀ䜚㝖䛟䠄2䠅䚹ỈὙ䛧䚸ỿ䜣䛰✀Ꮚ䜢㞟䜑䚸㏿䜔䛛䛻஝⇱䛧䚸ಖᏑ䛩䜛䠄3䠅䚹䝆䜸䜴᱂ᇵ䛻䛴䛴䛔䛶䝆䜸䜴⏕⸆ྡ䠖䝆䜸䜴䠄ᆅ㯤䠅ᇶཎ᳜≀䠖䜰䜹䝲䝆䜸䜴㻌 Rehmannia glutinosa Liboschitz
var. purpurea Makinoཪ䛿䜹䜲䜿䝆䜸䜴Rehmannia
glutinosa Liboschitz䠄䝂䝬䝜䝝䜾䝃⛉䠅ཎ⏘ᆅ䠖୰ᅜ
฼⏝㒊఩䠖᰿
⸆ຠ䠖Ṇ№䚸⦆ୗ䚸฼ᒀ₎᪉ฎ᪉䠖භ࿡ᆅ㯤୸䚸ඵ࿡ᆅ㯤୸䚸ᅄ≀‫‮‬䛺䛹 䚸୍⯡⏝₎᪉〇๣294ฎ᪉䛾ෆ䚸39ฎ᪉䛻㓄ྜ䚹⏕⏘ᆅ䠖᪥ᮏ䠄໭ᾏ㐨䚸㛗㔝䚸ዉⰋ䠅䚸୰ᅜ䠄ᒣす┬䚸Ἑ༡
┬䠅

஝䝆䜸䜴

䜰䜹䝲䝆䜸䜴

䜹䜲䜿䜲䝆䜸䜴

⏕⸆෗┿䠖་⸆ᇶ┙೺ᰤ◊䞉⸆⏝᳜≀⥲ྜ᝟ሗ䝕䞊䝍䝧䞊䝇䜘䜚─ 127 ─⇍䝆䜸䜴䝆䜸䜴䠄ᆅ㯤䠅䛾つ᱁䠄JP17䠅
䝆䜸䜴
Rehmannia Root
REHMANNIAE RADIXᆅ㯤㻌 ᮏရ䛿䜰䜹䝲ジオ䜴Rehmannia glutinosa Liboschitz
var. purpurea Makinoཪ䛿Rehmannia glutinosa
Liboschitz (Scrophulariaceae)䛾᰿(஝䝆䜸䜴)ཪ䛿䛭䜜䜢⵨䛧䛯䜒䛾(⇍䝆䜸䜴)䛷䛒䜛.
⣧ᗘヨ㦂
 (1) 㔜㔠ᒓ䚾1.07䚿㻌 ᮏရ䛾⢊ᮎ3.0 g䜢䛸䜚䠈➨3ἲ䛻䜘 䜚᧯స䛧䠈ヨ㦂䜢⾜䛖.ẚ㍑ᾮ䛻䛿㖄ᶆ‽ᾮ3.0
mL䜢ຍ䛘䜛(10 ppm௨ୗ).
 (2) 䝠⣲䚾1.11䚿㻌 ᮏရ䛾⢊ᮎ0.40 g䜢䛸䜚䠈➨4ἲ䛻䜘䜚᳨ᾮ䜢ㄪ〇䛧䠈ヨ㦂䜢⾜䛖(5 ppm௨ୗ).
⅊ศ䚾5.01䚿㻌 6.0%௨ୗ.
㓟୙⁐ᛶ⅊ศ䚾5.01䚿㻌 2.5%௨ୗ.
㈓ἲ㻌 ᐜჾ㻌 ᐦ㛢ᐜჾ.

─ 128 ─䝆䜸䜴䠄ᆅ㯤䠅䛾つ᱁䠄JP17䠅⏕⸆䛾ᛶ≧㻌 1) ஝䝆䜸䜴㻌 ᮏရ䛿䠈୍➃ⱝ䛧䛟䛿୧➃䛜⣽䛟䛺䛳䛯ሢ≧ཪ䛿⣳㗽ᙧ䜢࿊䛧䠈㛗䛥5 ࠥ 10 cm䠈ᚄ0.5 ࠥ3.0 cm䛷䠈䛸 䛝䛻ᢡ䜜䠈ཪ䛿ⴭ䛧䛟ኚᙧ䛧䛶䛔䜛.እ㠃䛿㯤〓Ⰽ䠈㯮〓Ⰽཪ䛿㯮Ⰽ䜢࿊䛧䠈῝䛔⦪⁁ཬ䜃䛟䜃䜜䛜䛒䜛.㉁䛿ᰂ䜙䛛䛔. ᶓษ㠃䛿㯤〓Ⰽ䠈㯮〓Ⰽཪ䛿㯮Ⰽ䛷䠈࿘㎶㒊䜋䛹Ⰽ䛜⃰䛔.
㻌 ᮏရ䛿≉␗䛺䛻䛚䛔䛜䛒䜚䠈࿡䛿ึ䜑ഹ䛛䛻⏑䛟䠈ᚋ䛻䜔䜔ⱞ䛔.
㻌 ᮏရ䛾ᶓษ∦䜢㙾᳨䚾5.01䚿䛩䜛䛸䛝䠈䝁䝹䜽ᒙ䛿7 ࠥ15 ᒙ䛷䠈⓶㒊䛿඲䛶ᰂ⤌⧊䛛䜙䛺䜚䠈〓Ⰽ䛾ศἪ≀䜢ྵ䜐⣽⬊䛜ᩓᅾ䛩䜛.ᮌ㒊䛿䜋䛸䜣䛹ᰂ⤌⧊䛛䜙䛺䜚䠈㐨⟶䛿ᨺᑕ≧䛻㓄ิ䛧䠈୺䛸䛧䛶⥙⣠㐨⟶䛷䛒䜛.
㻌 2) ⇍䝆䜸䜴㻌 ᮏရ䛿䠈୙つ๎䛺ሢ≧䠈୍➃ⱝ䛧䛟䛿୧➃䛜⣽䛟䛺䛳䛯ሢ≧ཪ䛿⣳㗽ᙧ䜢࿊䛧䠈㛗䛥5 ࠥ10 cm䠈ᚄ0.5 ࠥ3.0cm䛷䛒䜛.እ㠃䛿㯮Ⰽ䜢࿊䛧䠈㏻౛ගἑ䛜䛒䜚䠈῝䛔⦪⁁ཬ䜃䛟䜃䜜䛜䛒䜛.㉁䛿ᰂ䜙䛛䛟⢓ᛶ䛷䛒䜛.ᶓษ㠃䛿㯮Ⰽ䛷䛒䜛.
㻌 ᮏရ䛿≉␗䛺䛻䛚䛔䛜䛒䜚䠈࿡䛿ึ䜑⏑䛟䠈ᚋ䛻ഹ䛛䛻ⱞ䛔.
㻌 ᮏရ䛾ᶓษ∦䜢㙾᳨䚾5.01䚿䛩䜛䛸䛝䠈䝁䝹䜽ᒙ䛿7 ࠥ15 ᒙ䛷䠈⓶㒊䛿඲䛶ᰂ⤌⧊䛛䜙䛺䜚䠈〓Ⰽ䛾ศἪ≀䜢ྵ䜐⣽⬊䛜ᩓᅾ䛩䜛.ᮌ㒊䛿䜋䛸䜣䛹ᰂ⤌⧊䛛䜙䛺䜚䠈䛧䜀䛧䜀ᰂ⤌⧊䛾୍㒊䛜ቯ䜜✵㝽䛜ぢ䜙䜜䜛.㐨⟶䛿ᨺᑕ≧䛻㓄ิ䛧䠈୺䛸䛧䛶⥙⣠㐨⟶䛷䛒䜛.

─ 129 ─⏕⸆䝆䜸䜴䛾ရ㉁䘆࿴₎⸆䛾Ⰻྰ㚷ูἲཬㄪ〇᪉䠄୍Ⰽ┤ኴ㑻⦅㻌 ྤ㬅ᇽ᭩ᗑ䠅㻌䘆⏕ᆅ㯤䛿ᙧ䛜ᑠᣦ䛾䜘䛖䛷䚸㯤㉥Ⰽ䛾⫧䛳䛯㛗䛔₶䛔䛾ከ䛔䜒䛾䛜䜘䛔䚹⒓䛫䛶ᑠ䛥䛔⇱䛔䛶䛔䜛䜒䛾䛿䜘䛟䛺䛔䚹䘆஝ᆅ㯤䛿෤ᮇ䛻᥇㞟䛧䚸┤䛠䛻᪥ග䛻ᙜ䛶䛶஝䛛䛧䛯䜒䛾䚹⫧䛘䛯኱䛝䛔ရ䛾እ⓶䛜⅊Ⰽ䛷䚸ෆ㒊䛜⣸㯮Ⰽ䛷࿡䛾⏑䛔ᑡ䛧ⱞ䛔䜒䛾䛜䜘䛔䚹
䘆⇍ᆅ㯤䛿⵨䛧䛶஝䛛䛧䛯䜒䛾䛷䚸኱䛝䛔Ⰽ䛾⁽䛾䜘䛖䛻㯮䛔ග⃝䛾䛒䜛⏑䛔䜒䛾䛜Ⰻရ䛷䛒䜛䚹䘆⸆⏝᳜≀᱂ᇵ᥇཰ἲ䠄ส⡿㐩ኵ䚸ⱝᯘᴿ
ᅄ㑻ඹⴭ㻌 ༡ᲄ᭩ᗑ䠅㻌䘆⏕ᆅ㯤䛿᩿㠃㯤㉥Ⰽ䜢࿊䛧䚸㛗኱䛻䛧䛶₶䛔䛾䛒䜛䜒䛾䜢Ⰻရ䛸䛩䜛䚹䘆⇍ᆅ㯤䛿᩿㠃⣸㯮Ⰽ䜢࿊䛧䚸⁠࿡䛒䜛䜢Ⰻရ䛸䛩䜛䚹
─ 130 ─✀㻌 㢮䜰䜹䝲䝆䜸䜴

䜹䜲䜿䜲䝆䜸䜴

ⴥ䛾ୖ㠃䛾Ⰽ䛿⃰⥳Ⰽ䚸⿬㠃䛿㉥࿡䜢ᖏ䜃䜛䚹ⴥᩘ䛿ᑡ䚹ⰼ䛾௜䛝᪉䛿ᐦ䚹᰿䛿⣽䛟䚸㛗䛟䚸ඛ➃㒊䛿⣽㛗䛔⣳㗽ᙧ䛷䚸Ⰽ䛿㯤ᶳⰍ䚹ⴥ䛾ୖ㠃䛾Ⰽ䛿䜔䜔ⷧ䛔⥳Ⰽ䚸⿬㠃䛿䜋䛸䜣䛹㉥࿡䜢ᖏ䜃䛺䛔䚹ⴥᩘ䛿ከ䚹ⰼ䛾௜䛝᪉䛿⢒䚹᰿䛿ኴ䛟䚸㛗䛥䛿୰䚸ඛ➃㒊䛿ኴ䛔⣳㗽ᙧ䛷䚸Ⰽ䛿ῐ㯤ᶳⰍ䚹䛂⸆⏝᳜≀㻌 ᱂ᇵ䛸ရ㉁ホ౯䛃㻌 Part 1㻌 䠄⸆஦᪥ሗ♫䚸1992ᖺ䠅 䜘䜚

─ 131 ─䝆䜸䜴᱂ᇵ䛾ᐇ㝿䝆䜸䜴᱂ᇵ㐺ᆅ䞉Ẽೃ䛿 ᬮ䛺ᆅᇦ䛻㐺䛩䜛䚹䞉ᅵ㉁䛿⪔ᅵ䛜῝䛟䛶⭾㌾䛺ᇰᅵ䚸ᇰተᅵ䚸◁ተᅵ䛻㐺䛩䜛䚹
䞉᪥↷୪䜃䛻᤼ỈⰋዲ䛺⫧Ỻᆅ䛻㐺䛩䜛䚹ከ‵䛾ኳೃ䛸᤼Ỉ୙Ⰻ䛾ᅵᆅ䛜᭱䜒୙㐺䛷䛒䜛䚹䝆䜸䜴᱂ᇵ䛾せⅬ䚸᳜≀䛾≉㉁1䠅⦾Ṫ䛿᰿䠄᰿ⱼ䠅䛻䜘䜛䚹
2䠅᱂ᇵᖺᩘ䛿䠍ᖺ䚹䠐᭶ୗ᪪ࠥ䠑᭶ୖ᪪䛻✀᰿䜢᳜䛘௜䛡䚸11᭶ୗ᪪ࠥ12᭶䛻཰✭䛩䜛䚹
3䠅ⴥ⿬䛻ᅵ䛜௜╔䛩䜛䛾䜢᎘䛖䛯䜑䚸᮲㛫䚸ᰴ㛫䛻ᩜⲡ䜢᪋䛩䚹
4䠅㐃స䜢᎘䛖䛯䜑䚸ྠ୍ᆅ䛷䛾᱂ᇵ䛿ᩘᖺ䜢㝸䛶䛶⾜䛖䚹5䠅✀᰿䛾㈓ⶶ䛿↓⑓䛾ᰴ䛛䜙㑅䜃䚸඲ᙧ䛾䜎䜎㈓䛘䜛䚹ప ཬ䜃ຍ‵᮲௳ୗ䛷䛾㈓ⶶ䛿᰿䜢⭉䜙䛫䜛䛯䜑䚸༑ศ␃ព䛩䜛䚹─ 135 ─㏣ ⫧⏕⫱┦࡜సᴗ

─ 136 ─‫ۼ‬㏣⫧ࠉ㸦Dᙜࡾ㸧ࠉࠉࠉ㸯ᅇ┠
ࠉࠉࠉࠉ❅ࠉ⣲㸸㸱NJ
ࠉࠉࠉࠉ⇥ࠉ㓟㸸㸰NJ
ࠉࠉࠉࠉຍࠉ㔛㸸㸱NJ‫ۑ̿ۑ‬ᩜࠉࡁࠉⲡ

సᴗࡢෆᐜ✀ࠉ᰿ࠉ㈓ࠉⶶ

‫ⱑ✀ۼ‬㸦⩣ᖺࡢ✀᰿㸧ࡢಖᏑࠉࠉࠉ೺඲࡞᰿ⱼࢆ㛗࠸ࡲࡲ࡛㸪࢖ࣔ✰࡟㈓ⶶࡍࡿࠋ

‫཰ۼ‬㔞ࠉࠉࠉDᙜࡾ㸸㹼NJࠉ㸦⏕᰿㔜㔞㸧‫࣭✭཰ۼ‬ㄪ〇ࠉࠉࠉ᭶ୗ᪪㹼᭶ୗ᪪࡟࠿ࡅ࡚᥀ࡾྲྀࡿࠋ
ࠉࠉࠉὶỈ࡛ᅵ◁ࢆὙ࠸ⴠ࡜ࡋ㸪஝⇱ࡍࡿࠋ‫ۑ̿ۑ‬཰ࠉ✭ࠉᮇ

䛂⸆⏝᳜≀㻌 ᱂ᇵ䛸ရ㉁ホ౯䛃㻌 Part 1㻌 䠄⸆஦᪥ሗ♫䚸1992ᖺ䠅 䜘䜚ࠉࠉࠉ㸰ᅇ┠‫ۼ‬᳜࠼௜ࡅ
ࠉࠉࠉࠉ❅ࠉ⣲㸸㸱NJ
ࠉࠉࠉ᮲㛫㸸⣙FPࡢ㧗␏ࠉࠉࠉࠉ⇥ࠉ㓟㸸㸰NJ
ࠉࠉࠉᰴ㛫㸸⣙FPࡢ㸰᮲᳜࠼ࠉࠉࠉࠉຍࠉ㔛㸸㸱NJࠉࠉࠉ✀᰿㸸㹼FP࡟ษ᩿ࡋࡓࡶࡢ

‫ۼ‬ᇶ⫧ࠉ㸦Dᙜࡾ㸧ࠉࠉࠉሁࠉࠉ⫧㸸NJ
ࠉࠉࠉ⳯✀Ἔ⢑㸸NJ‫‽ࡢ⏿ۼ‬ഛࠉࠉࠉⱞᅵ▼⅊㸸S+㹼ࢆ┠ᶆ᳜࠼௜ࡅ‫ۑ̿ۑ‬

᭶
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

᪪ୖ ୰ ୗ ୖ ୰ ୗ ୖ ୰ ୗ ୖ ୰ ୗ ୖ ୰ ୗ ୖ ୰ ୗ ୖ ୰ ୗ ୖ ୰ ୗ ୖ ୰ ୗ䝆䜸䜴䛾᱂ᇵᬺ㻌

㏣ ⫧


᪋㻌 ⫧
ᇶ⫧

㏣⫧

䠄10 aᙜ䛯䜚䠅ሁ⫧㻌 㻌 㻌 㻌 1,000ࠥ2,000 kgⱞᅵ▼⅊㻌 㻌 㻌 㻌 50ࠥ100 kg⳯✀Ἔ⢑㻌 㻌 㻌 㻌 㻌 㻌 㻌 120 kg㻌 1ᅇ┠䠄䠒᭶୰᪪䠅㻌 㻌 㻌 ❅⣲㻌 㻌 㻌 3 䡇䡃㻌 㻌 㻌 䝸䞁㓟㻌 㻌 2 䡇䡃
㻌 㻌 㻌 䜹䝸㻌3 䡇䡃

㻌 2ᅇ┠䠄10᭶ୖ᪪䠅㻌 㻌 㻌 ❅⣲㻌
䝸䞁㓟
䜹䝸

3 䡇䡃
2 䡇䡃
3 䡇䡃㻌

䛂⸆⏝᳜≀㻌 ᱂ᇵ䛸ရ㉁ホ౯䛃㻌 Part 1 (⸆஦᪥ሗ♫䚸1992ᖺ) ᨵኚᅵተ䛾✀㢮䚸๓స䛾≧ἣ䛻䜘䛳䛶␗䛺䜛䛾䛷䛒䛟䜎䛷୍౛䛷䛒䜛䚹䞉❅⣲䜢ከ㔞䛻᪋䛧䚸㐺ᐅ䜹䝸⫧ᩱ䜢ే⏝䛩䜛䚹ⲡᮌ⅊䛿❅⣲⫧ᩱከ⏝䛾ሙྜ୪䜃䛻⑓ᐖண㜵ୖ᭷ຠ䛷䛒䜛䚹㻌㻌䞉䝆䜸䜴䛾᰿ⱼ䛿⛅ᮇᛴ㏿䛻⫧኱䛩䜛䛛䜙䚸䠕᭶ୖ᪪㡭䜘䜚10᭶୰ୗ᪪㡭䜎䛷䛻ከ㔞᪋䛩䚹㻌㻌㻌 㻌 㻌 㻌 㻌 䠄௨ୖ䚸ส⡿䜙䚸䛂⸆⏝᳜≀᱂ᇵ᥇཰ἲ䛃䠄༡ᲄ᭩ᗑ䠅䜘䜚䠅㻌─ 137 ─⦾Ṫἲ䞉᳜䛘௜䛡䜰䜹䝲䝆䜸䜴䛾✀᰿ⱼ䜹䜲䜿䜲䝆䜸䜴䛾✀✀᰿ⱼ⦾Ṫἲ䠖᰿ⱼ䜢⏝䛔䜛䚹᳜䛘௜䛡䠖᳜䛘௜䛡᫬ᮇ䛿䠐᭶ୗ᪪䛛䜙䠑᭶ୖ᪪㻌 㻌 㻌 㻌 㻌 㻌 㻌 䠄ᐮ෭ᆅ䛷䛿䠑᭶୰᪪䡚䠒᭶ୖ᪪䠅䜰䜹䝲䝆䜸䜴䠖✀᰿䜢㛗䛥10 cm๓ᚋ䛻ษ᩿䛧䛶⏝䛔䜛䠄✀᰿䛾≧ែ䛻䜘䜚䚸㐺ᐅ኱䛝䛥䜢ㄪᩚ䛩䜛䠅䚹
䜹䜲䜿䜲䝆䜸䜴䠖ᑠ䛥䛔᰿ⱼ䜢䛭䛾䜎䜎⏝䛔䜛䚹

─ 138 ─

᳜䛘௜䛡
ᖹ␇᱂ᇵ

㧗␇䞉䝬䝹䝏᱂ᇵ䜹䜲䜿䜲䝆䜸䜴
⟶⌮ᶵ䛷䛾㧗␇䞉䝬䝹䝏䛾タ⨨䜰䜹䝲䝆䜸䜴

䝬䝹䝏䛻✰䜢㛤䛡䚸✀᰿䜢᳜䛘௜䛡䚸そᅵ䛩䜛䚹─ 139 ─㧗␇䞉䝬䝹䝏᱂ᇵ⏕⫱ึᮇ䠄䠒
䠒᭶䠅⏕⫱୰ᮇ䠄䠕
䠕᭶䠅⏕⫱ᚋᮇ䠄11᭶᭶䠅㧗␇䞉䝬䝹䝏᱂ᇵ
␇ᖜ80ࠥ100 cm䚸ᰴ㛫
20 cm䠄෗┿䛿䝅䝹䝞䞊䝬䝹䝏䚸
␇ᖜ100 cm䚸ᰴ㛫 50 cm䠅
䜰䜹䝲䝆䜸䜴䠄䠕
䠕᭶䠅䘆䜾䝸䞊䞁䝬䝹䝏ཬ䜃㯮䝬䝹䝏䛿ⓑ㯮䝬䝹䝏䚸〄ᆅ䛻ẚ䜉ᆅ 䛜㧗䛟䚸ⴌⱆ䚸ᆅୖ㒊䛾⏕⫱ᗘྜཬ䜃ᆅୗ㒊཰㔞䛜㧗䛔ሗ࿌䛜䛒䜛㻌 䠄ὠᆏ䜙䚸᪥ᮏ⏕⸆Ꮫ఍➨63ᅇᖺ఍ᐩᒣ2016䠅䚹─ 140 ─⑓ᐖ⹸䜴䜲䝹䝇⑓䝰䝄䜲䜽⑕≧

䝛䝁䝤䝉䞁䝏䝳䜴
䝛䝁䝤䝉䞁䝏䝳䜴

䝛䜾䝃䝺䝉䞁䝏䝳䜴㢮
㢮䛻䜘䜛
᰿䛾⭉ᩋ

䝶䝖䜴䝮䝅

᰿䛾⭉䜚

䝶䝖䜴䝮䝅

䝆䜸䜴䛻㐺ᛂ䛾䛒䜛㎰⸆䛿䛺䛟䚸䛂㔝⳯㢮䛃䛻㐺⏝䛾
䛒䜛㎰⸆䛻‽ᣐ䛩䜛䚹

─ 141 ─཰✭䞉཰㔞
཰✭ᮇ䠖11᭶ୗ᪪ࠥࠥ12᭶ᆅୖ㒊䛜ᯤ䜜ጞ䜑䛯㡭䛻᰿䜢᥀䜚ྲྀ䜛䚹ỈὙᚋ䚸᰿䛾୰䛜㯮ኚ䛩䜛䜎䛷஝⇱䛩䜛䚹᰿䛿ㄪ〇ἲ䛻䜘䜚㩭ᆅ㯤䚸஝ᆅ㯤䚸⇍ᆅ㯤䛜䛒䜛䛜䚸⇍ᆅ㯤䛾ㄪ〇䛿ᢏ⾡䜢せ䛩䜛䚹་⸆ᇶ┙೺ᰤ◊䞉⟃Ἴ◊✲㒊䛻䛚䛡䜛཰✭㢼ᬒ䠄1988ᖺ䠅䜹䜲䜿䜲䝆䜸䜴

䜰䜹䝲䝆䜸䜴

཰㔞䠖10aᙜᙜ䛯䜚⏕⏕᰿㔜㔞㻌㻌 1,500ࠥ
ࠥ1,800 kg✀᰿䛾䛾㈓ⶶ䠖೺඲䛺᰿ⱼ䜢㑅䜃䚸ᰴ䛾䜎䜎䜸䜺䜽䝈䜔䝰䝭䜺䝷䛾୰䛻ධ䜜㈓ⶶ䛩䜛䚹㈓ⶶ
ⶶ䛻‽䛨䚸13ࠥ15Υ䛜ᮃ䜎䛧䛔䚹
─ 142 ─ᗘ䛿䝃䝒䝬䜲䝰䛾㈓⸆⏝స≀⏘ᆅᨭ᥼༠㆟఍㻌୍⯡♫ᅋἲே
඲ᅜ㎰ᴗᨵⰋᬑཬᨭ᥼༠఍
䛈107-0052
ᮾி㒔 ༊㉥ᆏ1-9-13 ୕఍ᇽ䝡䝹9㝵
TEL 03䠄5561䠅9562
URL http://www.jadea.jp
E-MAIL yakuyo@jadea.jp᪥ᮏ₎᪉⏕⸆〇๣༠఍
䛈103-0001
ᮾி㒔୰ኸ༊᪥ᮏᶫᑠఏ㤿⏫16-19㻌 㻌 㻌 㻌 㻌 㻌 㻌 㻌 㻌 Ώᯘ᪥ᮏᶫ䝡䝹3㝵
TEL 03䠄6264䠅8087
URL http://www.yakusankyo-n.org
E-MAIL soudan@yakusankyo-n.org