YUKAKO KOMAKI
Research Assistant Professor
University of Shizuoka
School of Food and Nutritional Sciences
Department of Environmental and Life Sciences
Graduate Division of Nutritional and Environmental Sciences52-1 Yada, Suruga-ku, Shizuoka 422-8526, Japan
E-mail: ykomaki@u-shizuoka-ken.ac.jp
Phone: +81-54-264-5795

EDUCATION
Ph.D.

Environmental Engineering, University of Illinois, Urbana, IL, USA

2013

M.S.

Urban and Environmental Engineering, Kyoto University, Japan (Honor admission)

2007

B.S.

Global Engineering, Kyoto University, Japan

2005

PROFESSIONAL & RESEARCH EXPERIENCES
Research Assistant Professor
University of Shizuoka, Shizuoka, Japan
Department of Environmental and Life Sciences
Project: Nucleotide excision repair inhibition by dibromoacetonitrile
Project: Cell cycle disruption by haloacetonitriles
Project: Cellular senescence induced by cigarette sidestream smoke

7/1/2017present

Postdoctoral Scholar/JSPS Overseas Research Fellow
Stanford University, Stanford, CA, USA
Department of Civil and Environmental Engineering(PI: William A. Mitch)
Project: Protein degradation by reactive halogen species
Description: The objective of this project is to evaluate the contribution of blood plasma
halide to oxidative damage in proteins resulting in 1) amino acid residue degradationand 2) enzymatic activity destruction, via exposure to free radicals (e.g., OH*, CO3*−,
Cl*, Cl2*−, Br2*−, ClBr*−).
Project: Characterizing the formation of vegetable-derived disinfection byproducts
Description: The objective of this project is to investigate the formation of volatile
disinfection byproducts and oxidized amino acid residues during chlorination in foodprocessing.

6/18/20166/17/2017

Postdoctoral Research Associate
University of Illinois, Urbana, IL, USA
Department of Civil and Environmental Engineering
Project: Molecular mechanism for wavelength-specific UV inactivation of bacteriophage
PR772, a potential surrogate for waterborne human adenovirus (PI: Benito J. Mariñas)
Project: Investigating nuclear enzyme topoisomerase II as a putative molecular target of
haloacetonitriles in mammalian cell toxicity (PI: Michael J. Plewa)

12/1/20136/17//2016

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Project: Comparative cell toxicity of disinfection byproduct mixture(PIs: Benito J. Mariñas, Michael J. Plewa)
Graduate Research Assistant
University of Illinois, Urbana, IL, USA
Department of Civil and Environmental Engineering
Project: Mode of toxic action of DBPs: Genomic DNA damage induction, DNA damage
repair and cell cycle alterations induced by haloacetonitriles and haloacetic acids(PIs: Benito J. Mariñas, Michael J. Plewa)
Project: Development of a point-of-care platform for cytotoxicity assessment of DBPs
(PIs: Benito J. Mariñas, Michael J. Plewa, Logan G. Liu)
Project: Bone char fixed-bed reactor for fluoride removal (PI: Benito J. Mariñas)

8/16/200711/30/2013

Post-master Research Assistant
Kyoto University, Kyoto, Japan
Department of Urban and Environmental Engineering
Project: Elemental analysis of mineral scale from the remains of water towers in Pompeii,
Italy, using X-ray fluorescence (PI: Yoshihisa Shimizu)

4/1/20077/31/2007

M.S. Research
Kyoto University, Kyoto, Japan
Department of Urban and Environmental Engineering
Project: Microbial community analysis in bioremediation of oil contaminated soil undersulfate reducing conditions (PI: Yoshihisa Shimizu)

4/20053/2007

Study Abroad
University of Illinois, Urbana, IL, USA
Department of Civil and Environmental Engineering
Project: Trichloroethylene biodegradation using Dehalococcoides ethenogenes strain FL2
with varied amendments (PI: Kevin T. Finneran)

9/200512/2005

Senior Research
Kyoto University, Kyoto, Japan
Department of Global Engineering
Project: Microbial community analysis in polycyclic aromatic hydrocarbon degradation
experiment for oil contaminated soil (PI: Yoshihisa Shimizu)

4/20043/2005

TEACHING EXPERIENCES
Co-instructor, University of Shizuoka, Shizuoka, Japan
Introduction to Environmental Sciences (7037200)
Advanced Topics in Radiation Biology (26302800)
Environmental Sciences English II (7273000)
Experiments in Environmental and Life Sciences II (7272300)
Fundamental Experiments in Environmental (7276000)
Environmental Measuring (7271700)

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Spring 2019-2023
Spring 2018-2023
Spring 2018
Spring 2018, 2019, 2021-2023,
Fall 2020
Spring 2019, 2021-2023,
Fall 2020
Fall 2017, 2018
Spring 2019-2023

Curriculum Vitae

Primary Instructor, University of Illinois, Urbana, IL, USA
Water Quality Control Process I (CEE 537)
Co-Instructor, University of Illinois, Urbana, IL, USA
Environmental Engineering Laboratory (CEE 449)
Water Quality Control Process I (CEE 537)
Head Teaching Assistant, University of Illinois, Urbana, IL, USA
Environmental Engineering Laboratory (CEE 449)
Instructor: Professor Benito J. Mariñas
Duty: Tanzania field trip; Course material and assignment
preparation; Student advising for the team reports andpresentations
Guest Lectures, University of Illinois, Urbana, IL, USA
Environmental Engineering Laboratory (CEE 449)
Environmental Engineering Laboratory (CEE 449)
Water Quality Control Process I (CEE 537)
Certificate in Foundation of Teaching, Center for Innovation in
Teaching & Learning, University of Illinois, Urbana, IL, USA

Fall 2013, 2014

Spring 2016
Fall 2015
Spring 2013

Spring 2014
Spring 2013
Fall 2011
April 2013

PUBLICATIONS
Peer-Reviewed Journal Articles
1. Komaki, Y., Ono, S., Okuya, T., Ibuki, Y. Glucose starvation impairs NER and γ-H2AX after UVB
irradiation. Toxicol. In Vitro 2023, 86, 105503.
2. Tanaka, M., Komaki, Y., Toyooka, T., Ibuki, Y. Butyrate Enhances γ-H2AX Induced by
Benzo[a]pyrene. Chem. Res. Toxicol. 2022, 35(12), 2241-2251.
3. Komaki, Y., Suganuma, K., Ibuki, Y. Protective role of electrophile-reactive glutathione for DNA
damage repair inhibitory effect of dibromoacetonitrile. J. Environ. Sci. 2022, 117, 305-314.
4. Komaki, Y., Ibuki, Y., Inhibition of nucleotide excision repair and damage response signaling bydibromoacetonitrile: a novel genotoxicity mechanism of a water disinfection byproduct. J. Hazard.
Mater. 2022, 423, 127194.
5. Shikata, M., Toyooka, T., Komaki, Y., Ibuki, Y. 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanoneInduced Histone Acetylation via α7nAChR-Mediated PI3K/Akt Activation and Its Impact on γ-H2AX
Generation. Chem. Res. Toxicol. 2021, 34(12), 2512-2521.
6. Fukuda, T., Komaki, Y., Mori, Y., Ibuki, Y. Low extracellular pH inhibits nucleotide excision repair.
Mutat. Res. 2021, 867, 503374.
7. Ibuki, Y., Komaki, Y., Yang, G., Toyooka, T. Long-wavelength UVA enhances UVB-induced cell
death in cultured keratinocytes: DSB formation and suppressed survival pathway. Photochem.
Photobiol. Sci. 2021, 20(5), 639-652.
8. Choe, J. K., Hua, L.-C., Komaki, Y., Simpson, A. M. A., McCurry, D. L., Mitch, W. A. Evaluation ofhistidine reactivity and byproduct formation during peptide chlorination. Environ. Sci. Technol. 2021,
55(3), 1790-1799.
9. Yamashita, R., Komaki, Y., Yang, G., Ibuki, Y. Cell line-dependent difference in glutathione levels
affects the cigarette sidestream smoke-induced inhibition of nucleotide excision repair. Mutat. Res.
2020, 858-860, 503273.
10. Yang, G., Komaki, Y., Yoshida, I., Ibuki, Y. Formaldehyde inhibits UV-induced phosphorylation ofhistone H2AX. Toxicol. In Vitro 2019, 61, 104687.

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11. Komaki, Y., Simpson, A. M., Choe, J. K., Pinney, M. M., Herschlag, D., Chuang, Y. H., Mitch, W. A.
Serum electrolytes can promote hydroxyl radical-initiated biomolecular damage from inflammation.
Free Radic. Biol. Med. 2019, 141, 475-482.
12. Yang, G., Komaki, Y., Ibuki, Y. Aldehyde-mediated protein degradation is responsible for the
inhibition of nucleotide excision repair by cigarette sidestream smoke. Mutat. Res. 2018, 834, 42-50
13. Komaki, Y., Simpson, A. M.-A. Choe, J. K., Plewa, M. J., Mitch, W. A. Chlorotyrosines versus
volatile byproducts from chlorine disinfection during washing of spinach and lettuce. Environ. Sci.
Technol. 2018, 52(16), 9361-9369.
14. Komaki, Y., Plewa, M. J. Investigation of nuclear enzyme topoisomerase as a putative moleculartarget of monohaloacetonitrile disinfection by-products. J. Environ. Sci. 2017, 58, 231-238.
15. Kimura, S. Y., Vu, T. N., Komaki, Y., Plewa, M. J., Mariñas, B. J. Acetonitrile and Nchloroacetamide formation from the reaction of acetaldehyde and monochloramine. Environ. Sci.
Technol. 2015, 49(16), 9954-9963.
16. Yang, Y.*, Komaki, Y.*, Kimura, S. Y.*, Hu, H.-Y., Wagner, E. D., Mariñas, B. J., Plewa, M. J.
Toxic impact of bromide and iodide on drinking water disinfected with chlorine or chloramines.
Environ. Sci. Technol. 2014, 48(20), 12362-12369. (*These authors contributed equally to this work)
17. Komaki, Y., Mariñas, B. J., Plewa, M. J. Toxicity of drinking water disinfection byproducts: Cell
cycle alterations induced by the monohaloacetonitriles. Environ. Sci. Technol. 2014, 48(19), 1166211669.
18. Kimura, S. Y., Komaki, Y., Plewa, M. J., Mariñas, B. J. Chloroacetonitrile and N,2dichloroacetamide formation from the reaction of chloroacetaldehyde and monochloramine in water.
Environ. Sci. Technol. 2013, 47(21), 12382-12390.
19. Saenz de Jubera, A. M., Herbison, J. H., Komaki, Y., Plewa, M. J., Moore, J. S., Cahill, D. G.,
Mariñas, B. J. Development and performance characterization of a polyamide nanofiltration
membrane modified with covalently bonded aramide dendrimers. Environ. Sci. Technol. 2013,
47(15), 8642-8649.
20. Hsiao, A.*, Komaki, Y.*, Imaad, S. M., Mariñas, B. J., Plewa, M. J., Liu, G. L. Cytotoxicity analysis
of water disinfection byproducts with a micro-pillar microfluidic device. Lab Chip 2012, 12(20),3891-3900. (*These authors contributed equally to this work)
21. Komaki, Y., Pals, J., Wagner, E. D., Mariñas, B. J., Plewa, M. J. Mammalian cell DNA damage andrepair kinetics of monohaloacetic acid drinking water disinfection by-products. Environ. Sci. Technol.
2009, 43(21), 8437-8442.
22. Kumada, Y., Kisa, T., Ohkuma, T., Kuwano, Y., Tanaka, H., Shimizu, Y. Effects of surfactant addition
on PAHs degradation and microbial community. Journal of EICA 2007, 12(2/3), 45-52. (in Japanese)

PRESENTATIONS
Conference Oral Presentations
1. Ibuki, Y., Suzuki, T., Komaki, Y., Amamo, M. Aldehyde-induced premature senescence and DNA
damage repair. The The 52nd Annual Meeting of the Japanese Environmental Mutagen and Genome
Society, Fukuoka, Japan, November 11-12, 2023.
2. Komaki, Y., Katayama, K., Ibuki, Y. Effect on cell cycle by disinfection byproducts haloacetonitriles.
The 57th Annual Conference of Japan Society on Water Environment, Matsuyama, Japan, March 1517, 2023.
3. Mori, Y., Komaki, Y., Toyooka, T., Ibuki, Y. Heat stress-induced deoxyribonuclease I release andphosphorylation of histone H2AX. The 95th Annual Meeting of the Japanese Biochemical Society,
Nagoya, Japan, November 9-11, 2022.

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4. Suzuki, T., Amano, M., Komaki, Y., Ibuki, Y. Delay of nucleotide excision repair and the formationof DSBs in senescence cells. The 95th Annual Meeting of the Japanese Biochemical Society, Nagoya,Japan, November 9-11, 2022.
5. Suzuki, T., Amano, M., Komaki, Y., Ibuki, Y. Delay of nucleotide excision repair and DSBs
formation in senescence cells. The 65th Annual Meeting of the Japanese Radiation Research Society,
Osaka, Japan, September 15-17, 2022.
6. Ibuki, Y., Komaki, Y., Kumagai, H. Delayed UV-induced DNA damage repair and translocation of
XPC to nucleolus by heat stress. The 44th Annual Meeting of the Japanese Society for Photomedicine
and Photobiology, Tokyo, Japan, June 25-26, 2022.
7. Komaki,Y., Suganuma, K., Ibuki, Y. The role of glutathione in the toxicity of disinfection by-productdibromoacetonitrile. The 56th Annual Conference of Japan Society on Water Environment, March 1618, 2022. (Online)
8. Suzuki, T., Amano, M., Komaki, Y., Ibuki, Y. Senescence delayed UV-induced DNA damage repair
in association with DDR factor phosphorylated histone H2AX. The 94th Annual Meeting of theJapanese Biochemical Society, Japan, November 3-5, 2021. (Online)
9. Mori, Y., Komaki, Y., Fukuda, T., Toyooka, T., Ibuki, Y. Heat stress-caused actin disruption andphosphorylation of histone γ-H2AX. The 64th Annual Meeting of the Japanese Radiation ResearchSociety, Japan, September 22-24, 2021. (Online)
10. Okuya, T., Ono, S., Komaki, Y., Ibuki, Y. Histone modification and UV-induced DNA damage repair
response by cigarette sidestream smoke. The 42nd Annual Meeting of the Japanese Society for
Photomedicine and Photobiology, Online, Japan, January 22-23, 2021.
11. Mori, Y., Fukuda, T., Komaki, Y., Toyooka, T., Ibuki, Y. Heat stress-induced cytoskeleton change andphosphorylation of histone H2AX. The 49th Annual Meeting of the Japanese Environmental Mutagen
Society, Numadzu, Japan, November 26-27, 2020.
12. Suzuki, T., Amano, M., Komaki, Y., Ibuki, Y. Senescence-associated alteration of UV-induced
histone γ-H2AX. The 49th Annual Meeting of the Japanese Environmental Mutagen Society,
Numadzu, Japan, November 26-27, 2020.
13. Okuya, T., Yang, G., Komaki, Y., Ibuki, Y. Cigarette side stream smoke decrease UV-induced DNA
damage repair and changes histone levels. The 49th Annual Meeting of the Japanese Environmental
Mutagen Society, Numadzu, Japan, November 26-27, 2020.
14. Komaki, Y., Ibuki, Y. Nucleotide excision repair inhibition by dibromoacetonitrile. The 54th Annual
Meeting of the Japan Society on Water Environment, Morioka, Japan, March 16-18, 2020.
(Cancelled)
15. Komaki, Y., Ibuki, Y. Nucleotide excision repair disruption by dibromoacetonitrile. The 6th AsianCongress on Environmental Mutagens and the 48th Annual Meeting of the Japanese Environmental
Mutagen Society, Tokyo, Japan, November 18-20, 2019.
16. Amano, M., Komaki, Y., Ibuki, Y. Histone modification change with aging and repair response to
UV-induced DNA damage. The 92nd Annual Meeting of the Japanese Biochemical Society,
Yokohama, Japan, September 18-20, 2019.
17. Amano, M., Komaki, Y., Ibuki, Y. Histone modification change with aging and repair response to
UV-induced DNA damage. The 41st Annual Meeting of the Japanese Society for Photomedicine andPhotobiology, Toyama, Japan, July 19-20, 2019.
18. Tanaka, M., Komaki, Y., Toyooka, T., Ibuki, Y. HDAC inhibitor enhances γ-H2AX induced bybenzo[a]pyrene. The 47th Annual Meeting of the Japanese Environmental Mutagen Society, Kyoto,
Japan, November 1-2, 2018.

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19. Mitch, W., Komaki, Y., Choe, J. K. When ROS are not ROS: The effect of salts on the degradation ofprotein. The 255th American Chemical Society (ACS) National Meeting, New Orleans, LA, USA,
March 18-22, 2018.
20. Mitch, W., Komaki, Y., Simpson, A. Chlorotyrosines versus volatile byproducts from disinfection
during washing of lettuce and spinach. The 255th ACS National Meeting, New Orleans, LA, USA,
March 18-22, 2018.
21. Komaki, Y., Plewa, M. J. Investigation of molecular target of haloacetonitrile disinfection
byproducts. The 52nd Annual Meeting of the Japan Society on Water Environment, Sapporo, Japan,
March 15-17, 2018.
22. Mitch, W., Komaki, Y., Simpson, A. Chlorotyrosines as byproducts of disinfection during washing oflettuce and spinach. Pittcon 2018, Orlando, FL, USA, February 26-March 1, 2018.
23. Komaki, Y., Choe, J. K., Mitch, W. Formation of vegetable-derived disinfection byproducts. The
253rd ACS National Meeting, San Francisco, CA, USA, April 2-6, 2017.
24. Komaki, Y., Choe, J. K., Mitch, W. Impact of halides on the degradation of amino acid residues inbiomolecules. The 253rd ACS National Meeting, San Francisco, CA, USA, April 2-6, 2017.
25. Komaki, Y., Mariñas, B. J., Plewa, M. J. Cell cycle alterations induced by haloacetonitrile
disinfection byproducts. The 248th ACS National Meeting, San Francisco, CA, USA, August 10-14,
2014.
26. Komaki, Y., Kimura, S. Y., Yang, Y., Mariñas, B. J., Wagner, E. D., Plewa, M. J. Comparative
toxicity of free and combined chlorination with different levels of halide ions. The 248th ACS
National Meeting, San Francisco, CA, USA, August 10-14, 2014.
27. Komaki, Y., Mariñas, B. J., Plewa, M. J. Analyses of cell cycle alteration induced byhaloacetonitriles: Toxicity of drinking water disinfection by-products. The 4th Annual Postdoctoral
Research Symposium. University of Illinois, Urbana, IL, USA, January 31, 2014.
28. Komaki, Y., Mariñas, B. J., Plewa, M. J. Measurement of genotoxicity induction and subsequent
repair efficiency rate of monohaloacetonitriles using mammalian cells. The 4th International Water
Association Asia-Pacific Region Conference, Tokyo, Japan, October 2-6, 2011.
29. Kumada, Y., Kisa, T., Ohkuma, T., Kuwano, Y., Shimizu, Y. Surfactant enhanced bioremediation ofoil contaminated soil. The 2nd International Conference on Environmental Science and Technology,
Houston, TX, USA, August 19-22, 2006.
30. Kumada, Y., Kisa, T., Ohkuma, T., Kuwano, Y., Tanaka, H., Shimizu, Y. Evaluation on the effect of
surfactants for bioremediation of oil contaminated soil. The 28th Symposium of the Association ofEnvironmental and Sanitary Engineering Research, Kyoto, Japan, July 18-19, 2006 (in Japanese).
31. Kumada, Y., Kisa, T., Kuwano, Y., Koshikawa, H., Tashiro, E., Yasukagawa, T., Shimizu, Y.
Microbial community analysis of PAHs degradation in soil. Korea-Japan Joint Seminar on
Geoenvironmental Engineering, Seoul, South Korea, June 2005.
Conference Poster Presentations
32. Komaki, Y., Ibuki, Y. Cigarette sidestream smoke-induced cellular senescence and the effect ofhistone H2AX knockdown. The 52nd Annual Meeting of the Japanese Environmental Mutagen and
Genome Society, Fukuoka, Japan, November 11-12, 2023.
33. Narimichi, M., Komaki, Y., Ibuki, Y. Formation of DNA double strand breaks after coexposure to
UVA1 and UVB-relationship with cytosolic DNA-. The 52nd Annual Meeting of the JapaneseEnvironmental Mutagen and Genome Society, Fukuoka, Japan, November 11-12, 2023.
34. Shobu, K, Komaki, Y., Mori, Y., Ibuki, Y. Heat stress-induced DNA damage and cellular senescence.
The 96th Annual Meeting of the Japanese Biochemical Society, Fukuoka, Japan, October 31November 2, 2023.
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35. Narimichi, M., Komaki, Y., Ibuki, Y. DNA double strand breaks formation and PARP1 activation byco-exposure to long-wavelength UVA1 and UVB. The 96th Annual Meeting of the Japanese
Biochemical Society, Fukuoka, Japan, October 31-November 2, 2023.
36. Komaki, Y., Ibuki, Y. Cigarette sidestream smoke-induced cellular senescence and associated role ofhistone H2AX. The 51st Annual Meeting of the Japanese Environmental Mutagen and Genome
Society, Hiroshima, Japan, November 15-16, 2022.
37. Suzuki, T., Komaki, Y., Ibuki, Y. Formaldehyde induces premature senescence and delayed
nucleotide excision repair. The 51st Annual Meeting of the Japanese Environmental Mutagen and
Genome Society, Hiroshima, Japan, November 15-16, 2022.
38. Mori, Y., Komaki, Y., Toyooka, T., Ibuki, Y. A novel mechanism of γ-H2AX induction via nuclease
release from endoplasmic reticulum. The 51st Annual Meeting of the Japanese Environmental
Mutagen and Genome Society, Hiroshima, Japan, November 15-16, 2022.
39. Narimichi, M., Komaki, Y., Ibuki, Y. DNA double strand breaks formation and DNA release tocytosol by co-exposure to long-wavelength UVA1 and UVB. The 95th Annual Meeting of theJapanese Biochemical Society, Nagoya, Japan, November 9-11, 2022.
40. Ito, R., Komaki, Y., Ibuki, Y. Relationship between cellular senescence and MMP-1 elevated bycigarette smoke and ultraviolet rays. The 95th Annual Meeting of the Japanese Biochemical Society,
Nagoya, Japan, November 9-11, 2022.
41. Suzuki, T., Amano, M., Komaki, Y., Ibuki, Y. Delay of nucleotide excision repair and the formationof DSBs in senescence cells. The 95th Annual Meeting of the Japanese Biochemical Society, Nagoya,Japan, November 9-11, 2022.
42. Mori, Y., Komaki, Y., Toyooka, T., Ibuki, Y. Heat stress-induced deoxyribonuclease I release andphosphorylation of histone H2AX. The 95th Annual Meeting of the Japanese Biochemical Society,
Nagoya, Japan, November 9-11, 2022.
43. Mori, Y., Suzuki, T., Toyooka, T., Komaki, Y., Ibuki Y. Development of assessment method fortissue-aging using histone H2AX phosphorylation induced by heat stress. The 94th Annual Meeting of
the Japanese Biochemical Society, Japan, November 3-5, 2021. (Online)
44. Suganuma, K, Komaki, Y., Ibuki, Y. Disinfection byproducts dibromoacetonitrile facilitated cellularsenescence and affected DNA damage repair. The 94th Annual Meeting of the Japanese Biochemical
Society, Japan, November 3-5, 2021. (Online)
45. Kumagai, H., Mori, Y., Komaki, Y., Ibuki, Y. Elevated skin temperature inhibited UV-induced DNA
damage repair and the phosphorylation of histone H2AX. The 94th Annual Meeting of the Japanese
Biochemical Society, Japan, November 3-5, 2021. (Online)
46. Mori, Y., Suzuki, T., Toyooka, T., Komaki, Y., Ibuki, Y. A novel assessment method for tissue-aging
using histone H2AX phosphorylation induced by heat stress. The 50th Anniversary Annual Meeting of
the Japanese Environmental Mutagen Genome Society, Yokosuka, Japan, November 1-2, 2021.
47. Suzuki, T., Amano, M., Komaki, Y., Ibuki, Y. Senescence-caused change of γ-H2AX induction after
UV irradiation―relationship with delayed NER-protein release from damaged sites. The 50th
Anniversary Annual Meeting of the Japanese Environmental Mutagen Genome Society, Yokosuka,
Japan, November 1-2, 2021.
48. Komaki, Y., Ibuki, Y. Cigarette sidestream smoke induced cellular senescence and altered DNA
damage response. The 50th Anniversary Annual Meeting of the Japanese Environmental Mutagen
Genome Society, Yokosuka, Japan, November 1-2, 2021.
49. Okuya, T., Komaki, Y., Ibuki, Y. Alteration of γ-H2AX by glucose environment. The 50th
Anniversary Annual Meeting of the Japanese Environmental Mutagen Genome Society, Yokosuka,
Japan, November 1-2, 2021.

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50. Ibuki, Y., Komaki, Y., Yang, G., Toyooka, T. Long-wavelength UVA enhances UVB-induced cell
death in cultured keratinocytes: DSB formation and survival signal suppression. The 64th Annual
Meeting of the Japanese Radiation Research Society, Japan, September 22-24, 2021. (Online)
51. Suganuma, K., Komaki, Y., Ibuki, Y. Relationship between nucleotide excision repair inhibition andglutathione depletion by dibromoacetonitrile. The 55th Annual Meeting of the Japan Society on Water
Environment, Kyoto, Japan, March 10-12, 2021. (Online)
52. Komaki, Y., Ibuki, Y. Nucleotide excision repair disruption by dibromoacetonitrile. The 6th AsianCongress on Environmental Mutagens and the 48th Annual Meeting of the Japanese Environmental
Mutagen Society, Tokyo, Japan, November 18-20, 2019.
53. Ibuki,Y., Fukuda, T., Komaki, Y. Acid condition delays nucleotide excision repair. The 6th AsianCongress on Environmental Mutagens and the 48th Annual Meeting of the Japanese Environmental
Mutagen Society, Tokyo, Japan, November 18-20, 2019.
54. Shindo, T., Komaki, Y., Ibuki, Y. Chlorination of bisphenol A changed histone acetylation and DNA
damage response. The 6th Asian Congress on Environmental Mutagens and the 48th Annual Meetingof the Japanese Environmental Mutagen Society, Tokyo, Japan, November 18-20, 2019.
55. Fukuda, T., Komaki, Y., Ibuki, Y. Actin disruption causes DNA double strand breaks. The 6th AsianCongress on Environmental Mutagens and the 48th Annual Meeting of the Japanese Environmental
Mutagen Society, Tokyo, Japan, November 18-20, 2019.
56. Ibuki, Y., Ono, S., Okuya, T., Komaki, Y. Energy metabolism changes histone H2AX
phosphorylation after UV irradiation. The 62nd Annual Meeting of the Japanese Radiation ResearchSociety, Kyoto, Japan, November 14-16, 2019.
57. Amano, M., Komaki, Y., Ibuki, Y. Aging altered histone modification and repair response to UVinduced DNA damage. The 24th Shizuoka Forum on Health and Longevity, Shizuoka, Japan,
November 9-10, 2019.
58. Okuya, T., Komaki, Y., Ibuki, Y. Repair response to DNA damage altered by glucose concentration.
The 24th Shizuoka Forum on Health and Longevity, Shizuoka, Japan, November 9-10, 2019.
59. Fukuda, T., Komaki, Y., Ibuki, Y. Acidic condition delays nucleotide excision repair. The 24th
Shizuoka Forum on Health and Longevity, Shizuoka, Japan, November 9-10, 2019.
60. Ono, S., Komaki, Y., Ibuki, Y. The effect of glucose concentration in culture medium on
phosphorylation of histone H2AX induced by ultraviolet irradiation. The 92nd Annual Meeting of theJapanese Biochemical Society, Yokohama, Japan, September 18-20, 2019.
61. Amano, M., Komaki, Y., Ibuki, Y. Histone modification change with aging and repair response to
UV-induced DNA damage. The 92nd Annual Meeting of the Japanese Biochemical Society,
Yokohama, Japan, September 18-20, 2019.
62. Yang, G., Komaki, Y., Ibuki, Y. Formaldehyde inhibits UV induced phosphorylation of histone
H2AX. The 16th International Congress of Radiation Research, Manchester, UK, August 25-29, 2019.
63. Komaki, Y., Ibuki, Y. Dibromoacetonitrile disrupts nucleotide excision repair. Gordon Research
Conference on Water Disinfection, Byproducts and Health, South Hadley, MA, July 28-August 2,
2019.
64. Yang, G., Komaki, Y., Ibuki, Y. Cigarette sidestream smoke delays nucleotide excision repair:inhibited accumulation of repair proteins at DNA lesions. The 23rd Shizuoka Forum on Health andLongevity, Shizuoka, Japan, November 16-17, 2018.
65. Tanaka, M., Komaki, Y., Toyooka, T., Ibuki, Y. HDAC inhibitor enhances γ-H2AX induced bybenzo[a]pyrene. The 47th Annual Meeting of the Japanese Environmental Mutagen Society, Kyoto,
Japan, November 1-2, 2018.
66. Hirai, M., Komaki, Y., Ibuki, Y. Phosphorylation of histone H3 at serine 10 after exposure to UVA1,
Consortium of Biological Sciences (ConBio) 2017, Kobe, Japan, December 6-9, 2017

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67. Komaki, Y., Choe, J. K., Mitch, W. A. Application of disinfection chemistry to biochemistry:
Reactive halogen species as a potential culprit of oxidative stress in biological systems. Gordon
Research Conference on DBPs, South Hadley, MA, July 30-August 4, 2017.
68. Simpson, A., Komaki, Y., Choe, J. K., Mitch, W. A. Juxtaposing volatile DBP formation with theformation of tyrosine derivatives during the chlorination of spinach and lettuce. Gordon Research
Seminar & Conference on DBPs, South Hadley, MA, July 29-August 4, 2017.
69. Komaki, Y., Mariñas, B. J., Plewa, M. J. Inhibition of topoisomerase enzyme by haloacetonitrile
disinfection byproducts. Gordon Research Seminar & Conference on DBPs, South Hadley, MA,
August 8-14, 2015.
70. Komaki, Y., Mariñas, B. J., Plewa, M. J. Biological mechanism of the toxicity of haloacetonitrile
disinfection byproducts. Association of Environmental Engineering and Science Professors Research& Education Conference, New Haven, CT, June 13-16, 2015.
71. Komaki, Y., Mariñas, B. J., Plewa, M. J. DNA damage induction, DNA repair, and cell cycle
alterations by monohalogenated disinfection byproducts: Haloacetic acids and haloacetonitriles. The
248th ACS National Meeting, San Francisco, CA, August 10-14, 2014.
72. Komaki, Y., Mariñas, B. J., Plewa, M. J. Cell cycle blockage effect induced by haloacetonitriles in
Chinese hamster ovary cells. Association of Environmental Engineering and Science Professors
Research & Education Conference, Golden, CO, July 14-16, 2013.
73. Komaki, Y., Mariñas, B. J., Plewa, M. J. Toxicity of haloacetonitrile DBPs. Gordon Research
Conference on DBPs. South Hadley, MA, August 5-10, 2012.
74. Komaki, Y., Mariñas, B. J., Plewa, M. J. Elucidating DNA repair kinetics of haloacetonitriles in
Chinese hamster ovary cells and effect on cell cycle arrest. The 42nd Environmental Mutagen Society
Annual Meeting, Montréal, Québec, October 15-19, 2011.
75. Komaki, Y., Pals, J., Wagner, E. D., Mariñas, B. J., Plewa, M. J. Comparative DNA damage andrepair kinetics study of monohaloacetonitriles in mammalian cells. The 41st Environmental Mutagen
Society Annual Meeting, Fort Worth, TX, October 23-27, 2010.
76. Komaki, Y., Kimura, S., Pals, J., Wagner, E. D., Plewa, M. J., Mariñas, B. J. DNA repair kinetics
study of monohaloacetonitriles in mammalian cells. The 239th ACS National Meeting, San Francisco,
CA, March 21-25, 2010.
77. Komaki, Y., Pals, J., Wagner, E. D., Mariñas, B. J., Plewa, M. J. Comparative DNA damage andrepair kinetics study in mammalian cells by chloro-, bromo-, and iodoacetic acid. The 40th
Environmental Mutagen Society Annual Meeting, St. Louis, MO, October 24-28, 2009.
78. Komaki, Y., Pals, J., Wagner, E. D., Mariñas, B. J., Plewa, M. J. Comparative DNA damage andrepair kinetics study in mammalian cells by chloro-, bromo-, and iodoacetic acid. Gordon Research
Conference on DBPs. South Hadley, MA, August 9-14, 2009.
79. Pals, J., Komaki, Y., Wagner, E. D., Mariñas, B. J., Plewa, M. J. Comparative DNA damage andrepair kinetics study in mammalian cells by chloro-, bromo-, and iodoacetic acid. Material ResearchSociety Spring Meeting, San Francisco, CA, April 13-17, 2009.
80. Kumada, Y., Kimura, S., Mariñas, B. J., Pals, J., Wagner, E. D., Plewa M. J. DNA damage andrepair kinetics in mammalian cells by reactants, intermediates and products associated with thereaction of combined chlorine and formaldehyde in drinking water. The 235th ACS National Meeting,
New Orleans, LA, April 6-10, 2008.
81. Kumada, Y., Kisa T., Kuwano, Y., Koshikawa, H., Tashiro, E., Yasukagawa, T., Shimizu, Y.
Microbial community analysis in PAHs degradation experiment for oil contaminated soil. Workshop
on Groundwater and Soil Contamination and Prevention Measures against those Contamination,
Chiba, Japan, June 2005 (in Japanese).

Y. Komaki – University of Shizuoka

9 of 11Curriculum Vitae

INVITED TALKS
1. Komaki, Y. A novel genotoxicity mechanism of a water disinfection byproduct: Inhibition of
nucleotide excision repair and damage response signaling by dibromoacetonitrile. HKUST Forum on
Innovative Disinfection and Emerging Disinfection Byproducts, Hong Kong, March 25-26, 2023.
(Online)
2. Komaki, Y. The future of bioassay – DNA damage induction and repair of drinking water disinfection
byproducts. The 23rd Japan Society on Water Environment Symposium, Japan, September 9-10, 2020.
(Online)
3. Komaki, Y. Disinfection byproducts and their toxicity evaluations in wastewater reuse. The 2nd
Lecture Series on Leading Edge Wastewater Technologies, Environmental Engineering andSurrounding Areas, Japanese Society of Civil Engineers, Tokyo, Japan, January 31, 2019.
4. Komaki, Y. Protecting water and human health: Understanding toxicological property of
haloacetonitrile disinfection byproducts. The George Washington University, DC, August 7, 2017.
5. Komaki, Y. Characterize the formation of volatile disinfection byproducts and chlorinated tyrosine
during fresh produce washing. RIKEN Sakura Symposium, RIKEN, Yokohama, Japan, March 29-30,
2017.
6. Komaki, Y. Toward safe drinking water: How can toxicity assays play a role in environmental
engineering? Civil and Environmental Engineering Rising Stars workshop, Massachusetts Institute ofTechnology, Cambridge, MA, October 15-16, 2015.

AWARDS & HONORS
Selected for 15 Oral Presenters at RIKEN Sakura Symposium, RIKEN
Japan Science for the Promotion of Science Postdoctoral Fellowships for Research Abroad(189 out of 977, ~$100,000)
Elected Co-Chair of the 5th Disinfection Byproducts Gordon Research Seminar
Selected for Civil and Environmental Engineering Rising Stars workshop (20 out of 122),
Massachusetts Institute of Technology“Outstanding” in the List of Teachers Ranked as Excellent by Their Students (CEE 449:
Environmental Engineering Laboratory), Center for Innovation in Teaching and Learning,
University of Illinois at Urbana-Champaign
Gordon Conference Young Researcher FellowshipBest poster award, The 18th Annual Environmental Engineering and Science Spring
Symposium, University of Illinois at Urbana-Champaign
Racheff Graduate Student Travel Award, Environmental Engineering Science, University of
Illinois at Urbana-Champaign
WaterCAMPWS Student Leadership Council Conference Travel Grant
Student Travel Award, Environmental Mutagen Society
Graduate College Conference Travel Award (declined)
Invited to the Phi Kappa Phi Honor Society
Heiwa Nakajima Foundation Scholarship (24 out of 227, ~$48,000)
Exempt from repayment (~$9,000), Japanese Student Services Organization scholarship loan
program
Honor admission to the graduate college of Kyoto University

Y. Komaki – University of Shizuoka

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2012
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2009, 2011
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2007-2009
2007
2005

Curriculum Vitae

PROFESSIONAL SERVICES & ACTIVITIESAcademic Service Organizing Committee, The 47th Annual Meeting of the JapaneseEnvironmental Mutagen Society
Co-chair, Gordon Research Seminar on DBPs (elected)
Member, WASH-Toxics Interdisciplinary Working Group
Discussion Leader, Gordon Research Seminar on DBPs
Seminar Coordinator, Environmental Engineering Program Seminar(CEE 595AG), UIUC
Advisor to Student CEE 595AG Seminar Committee, UIUC
Graduate Student Organizer, Water for Life: Addressing a 21stCentury Crisis, Graduate College Focal Point Project, UIUC
Student Officer, Phi Kappa Phi Honor Society, UIUC
Departmental
Member, Cultural Awareness and Speech Enhancement, UIUC
Activity
Coordinator, Mariñas research group meeting, UIUC
Journal Review
Chemosphere
Environmental and Molecular Mutagenesis
Environmental Science and Technology
Environment International
Frontiers of Environmental Science and Engineering
Genes and Environment
Journal - American Water Works Association
Journal of Environmental Sciences
Journal of Hazardous Materials
Journal of Water and HealthNature Sustainability
Ozone Science & Engineering
Science of Total Environment
Water Research
MembershipJapan Society on Water Environment
The Molecular Biology Society of JapanThe Japanese Environmental Mutagen Society
Community
Volunteer for Japan Bio Community forum
Service & Activity Volunteer for Community and Campus Day of Service
Volunteer for Boneyard Creek Community Day litter clean up event
Engineering open house, exhibition of “Drinking Water Treatment,”
2nd place in the real-world division

Y. Komaki – University of Shizuoka

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Nov. 2018
July 2017
Since 2016
August 20152014-20152014- 20152010-20112009
2007-2012
2008

2016
2014
2012
2009

Curriculum Vitae