Isao Yokota
Department of Biostatistics,
Graduate School of Medicine,
Hokkaido University

N15, W7, Kita-ku, Sapporo 060-8638 JAPAN
Phone:+81-11-706-5896
Fax:+81-11-706-6050
Email:
yokotai@pop.med.hokudai.ac.jp
Homepage: http://yokotai.wordpress.com/

Personal
Born on November 19, 1987.
Japan Citizen.

Education
Ph.D. Health Science, The University of Tokyo, 2015.
Master of Public Health, The University of Tokyo, 2012.
B.S. Health Science, The University of Tokyo, 2010.

Employment
Primary Appointment
Oct 2018 – present

Associate Professor, Hokkaido University

Apr 2015 – Sep 2018

Assistant Professor, Kyoto Prefectural University of Medicine

Isao Yokota

2Secondary Appointments (Academic)
Aug 2022 – present

Guest researcher, University of Copenhagen

Dec 2018 – present

Visiting lecturer, Kyoto Prefectural University of Medicine

Apr 2021 – present

Part-time Lecturer, Kyoto University

Jul 2019 – Mar 2021

Visiting researcher, National Center for Global Health and Medicine

Apr 2018 – Mar 2019

Part-time Lecturer, Kyoto University

Apr 2018 – Sep 2018

Part-time Lecturer, Mukogawa Women’s University

Apr 2017 – Sep 2017

Part-time Lecturer, Mukogawa Women’s University

Dec 2012 – Mar 2015

Research Assistant, The University of Tokyo

May 2012 – Feb 2015

Program adviser, Teikyo University

May 2012 – Nov 2012

Research Assistant, The University of Tokyo

Apr 2012 – Mar 2013

Tutor, The University of Tokyo

Oct 2011 – Mar 2012

Teaching Assistant, The University of Tokyo

Research collaboration
Lecture about biostatistics
Lecture about biostatistics for master’s student
Research collaboration
Lecture about biostatistics for master’s student
Lecture about biostatistics for master’s student
Lecture about biostatistics for master’s student
Belong to Global Creative Leadership program.
Consultation of biostatistics for medical doctors, nurses and pharmacy researchers.
Belong to graduate school of medicine.
Support for a student studying abroad.
Belong to school of public health.

Secondary Appointments (Other)
Mar 2011 – Sep 2016

Statistical Analyst, Non-Profit Organization Japan Clinical Research Support Unit
Analyze data and plan for a statistical method.

Honors and Awards
Representative of the graduating students of health science in 2010, The University of Tokyo
Elected at professor meetings.

Research award of graduation theses in 2010, Health science and nurcing, Faculty of medicine, The
University of Tokyo
Elected at professor meetings.

Teaching
Graduate School
2020-present Statistical methods for clinical trials, Hokkaido University“Clinical trial design and CONSORT”, “Interim monitoring and Independent data monitoring committee” (4classes).

2020-present Advanced biostatistics, Hokkaido University(16 classes).

Isao Yokota

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2020-present Causal inference and clinical epidemiology, Hokkaido University“Epidemiologic design”, “Bias and counterfactual outcomes”, “Causal DAG”, “Propensity score”, “Measures forprediction model” and “Construct the statistical model”(10 classes).

2020-present Basic biostatistics, Hokkaido University“Clinical research and Biostatistics”, “Descriptive statistics”, “Estimating and Testing”, “Linear regression”,“Logistic regression” and “Survival analysis”(8 classes).

2019-present Mathematical statistics for biostatistics, Hokkaido University
Mathematical statistics (8 classes).

2018-present Statistical methods for clinical trials, Kyoto University“Interim monitoring and Independent data monitoring committee” (1 class).

2016-2019,2021 Special lecture in oncology, Teikyo University“How to interpret clinical trial papers” (1 class).

2019

Basic biostatistics, Hokkaido University“Clinical research and Biostatistics”, “Descriptive statistics”, “Estimating and Testing”, “Analysis of variance”,“Linear regression”, “Clinical trial design”, “Epidemiological study design”, “Bias in epidemiology” and “Survival
analysis” (16 classes, twice a year(total 32 classes)).

2019

Statistical methods for epidemiologic research, Hokkaido University

Design and bias on epidemiologic research (8 classes).

2019

Special lecture, Tokyo University of Science

Prediction model (1 class).

2017-2018

Biostatistics, Mukogawa Women’s University“Descriptive statistics”,“Statistical test and estimation”,“Observational study”,“Analysis of variance and linear
regression”,“Confounding and logistic regression”,“Reliability and validity of questionnaires” (7.5 classes).

2017

Special lecture in biostatistics, The University of Tokyo“The measures of predictive ability in survival analysis” (1 class).

2017

Biostatisticsal method in clinical research, Kyoto University“Interim monitoring” (1 class).

Undergraduate
2020-present Medical Statistics and Medical History, Hokkaido University, B1
For medical students(8 classes).

2019-present Medical Statistics and Data Science (Freshman Seminar), Hokkaido University, B1
Introduction to biostatistics and Conducting an epidemiologic study (15 classes).

2019-2020

Translational Research, Hokkaido University, B4“Introduction to clinical research” (1 classes).

2018-present Medical statistics, Hokkaido University, B3“Clinical research and Biostatistics”, “Descriptive statistics”, “Two group comparisons”, “Analysis of Variance”,“Epidemiologic design”, “Regression models” (6 classes).

2016-2018

Medical statistics, Kyoto Prefectural University of Medicine, B5“Observational study 1”, “Observational study 2” (3 classes).

Isao Yokota

2016-2018

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Clinical Pharmacology, Kyoto Prefectural University of Medicine, B6“Observational study” (1 class).

2015-2018

Biostatistics, Kyoto Prefectural University of Medicine, B4“Descriptive statistics”, “Two group comparisons”, “Analysis of variance and Linear regression” (3 classes).

2015-2016

Medical science practice, Kyoto Prefectural University of Medicine, B1

Teach descriptive method, randomization and test using counterfactural cards and JMP®for 2 days.

Society activities
The Biometrics Society of Japan (2012-)
Councilor (2017-2018,2021-) Planning Committee (2016-)

International Biometrics Society (2012-)
Social media liaison (2018-)

International Society of Clinical Biostatistics (2013, 2015, 2017-)
ENAR (2016-)

Committee
Biostatistics committee, Japan Children Cancer Group (2014-)
Protocol review committee, Japan Clinical Oncology Group (2019-)

Publications
Peer-Reviewed Journal Articles
168. Suzuki Y, Kaneko H, Yano Y, Okada A, Itoh H, Matsuoka S, Yokota I, Imaizumi T, Fujiu K, Michihata
N, Jo T, Takeda N, Morita H, Node K, Yasunaga H, Komuro I. Interaction of blood pressure andglycemic status in developing cardiovascular disease: analysis of a nationwide real-world database. J
Am Heart Assoc. [Epub ahead of print]
167. Ono S, Ishimaru M, Yokota I, Konishi T, Okada A, Ono Y, Matsui H, Itai S, Yonenaga K, Tonosaki
K, Watanabe R, Hoshi K, Yasunaga H. Risk of post-extraction bleeding with direct oral anticoagulant
compared with warfarin: Retrospective cohort study using large scale claims data in Japan. Thromb
Res. [Epub ahead of print]
166. Oguma A, Shimizu K, Kimura H, Tanabe N, Sato S, Yokota I, Takimoto-Sato M, Matsumoto-Sasaki
M, Abe Y, Takei N, Goudarzi H, Suzuki M, Makita H, Hirai T, Nishimura M, Konno S; Hi-CARAT
investigators. Differential role of mucus plugs in asthma: Effects of smoking and association withairway inflammation. Allergol Int. [Epub ahead of print]
165. Goudarzi H, Ikeda-Araki A, Bamai YA, Ito S, Inao T, Yokota I, Miyashita C, Kishi R, Konno S.
Potential determinants of T helper 2 markers and their distribution in school-aged children. Allergol
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164. Suzuki Y, Kaneko H, Yano Y, Okada A, Hashimoto Y, Itoh H, Matsuoka S, Yokota I, Fujiu K,
Michihata N, Jo T, Takeda N, Morita H, Kamiya K, Matsunaga A, Ako J, Node K, Yasunaga H,
Komuro I. Threshold of body mass index for the development of hypertension among Japanese adults.
J Nutr. [Epub ahead of print]
163. Nakano S, Kawamoto Y, Komatsu Y, Saito R, Ito K, Yamamura T, Harada K, Yuki S, Kawakubo K,
Sugiura R, Kato S, Hirata K, Hirata H, Nakajima M, Furukawa R, Takishin Y, Nagai K, Yokota I,
Ota KH, Nakaoka S, Kuwatani M, Sakamoto N. Analysis of the pancreatic cancer microbiome using
endoscopic ultrasound-guided fine-needle aspiration-derived samples. Pancreas. [Epub ahead of print]
162. Imaizumi K, Homma S, Nishida M, Soyama T, Shimura R, Kudo Y, Omotehara S, Yokota I, Takagi
R, Matsui H, Miyaoka Y, Ichikawa N, Yoshida T, Takahashi N, Taketomi A. Transabdominal ultrasonography for preoperative diagnosis of lymph node metastasis in colon cancer: a retrospective cohort
study. Cancer Diagn Progn. [Epub ahead of print]
161. Kida T, Matsuzaki K, Yokota I, Kawase N, Kadoya M, Inoue H, Kukida Y, Kaneshita S, Inoue T,
Wada M, Kohno M, Fukuda W, Kawahito Y, Iwami T. Latent trajectory modelling of pulmonary
artery pressure in systemic sclerosis: a retrospective cohort study. RMD Open. 2022; 8: e002673.
160. Suzuki Y, Kaneko H, Yano Y, Okada A, Itoh H, Ueno K, Matsuoka S, Fujiu K, Michihata N, Jo T,
Takeda N, Morita H, Yokota I, Node K, Yasunaga H, Komuro I. Dose-dependent relationship of bloodpressure and glycemic status with risk of aortic dissection and aneurysm. Eur J Prev Cardiol. 2022;
29: 2338-2346.
159. Takai S, Nakanishi N, Yokota I, Imai K, Yamada A, Kawasaki T, Kasahara T, Okada T, Sawada
T, Matoba S. Clot-regression effects of rivaroxaban in venous thromboembolism treatment in cancer
patients – a prospective interventional study. Sci Rep. 2022; 12: 21569.
158. Okada A, Yamaguchi S, Jo T, Yokota I, Ono S, Ikeda Kurakawa K, Nangaku M, Yamauchi T,
Kadowaki T Impact of body mass index on in-hospital mortality in older patients hospitalized forbacterial pneumonia with non-dialysis-dependent chronic kidney disease. BMC Geriatr. 2022; 22:950.
157. Yoshimura T, Ushigome E, Hata S, Takegami M, Hasegawa G, Tanaka T, Tsunoda S, Ohnishi M,
Yokota I, Ushigome H, Kitagawa N, Asano M, Hamaguchi M, Yamazaki M, Fukui M. Impact ofsustained hypertension on new cardiovascular events in patients with type 2 diabetes: KAMOGAWAHBP study. J Clin Hypertens. 2022; 24: 1561-1567.
156. Yamanaka Y, Yokota I, Yasumoto A, Morishita E, Horiuchi H. Time of Day of Vaccination Does Not
Associate With SARS-CoV-2 Antibody Titer Following First Dose of mRNA COVID-19 Vaccine. J
Biol Rhythms. 2022; 37: 700-706.
155. Uchinami Y, Fujita N, Ando T, Mizunoya K, Hoshino K, Yokota I, Morimoto Y. The relationshipbetween years of anesthesia experience and first-time intubation success rate with direct laryngoscopeand video laryngoscope in infants: a retrospective observational study. J Anesth. 2022; 36: 707-714.
154. Hata S, Ushigome E, Yoshimura T, Takegami M, Kitagawa N, Tanaka T, Hasegawa G, Ohnishi M,
Tsunoda S, Yokota I, Ushigome H, Asano M, Hamaguchi M, Yamazaki M, Fukui M. Maximum home
blood pressure and cardiovascular outcomes in patients with type 2 diabetes: KAMOGAWA-HBP
study. J Hypertens. 2022; 40: 2430-2437.
153. Matsuoka M, Onodera T, Yokota I, Iwasaki K, Hishimura R, Suzuki Y, Kondo E, Iwasaki N. Comparison of clinical features between patients with bone and soft tissue fibrosarcomas. J Surg Oncol.
2022; 126: 1299-1305.

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152. Murakami K, Iwasaki S, Oguri S, Tanaka K, Suzuki R, Hayasaka K, Fujisawa S, Watanabe C, Konno
S, Yokota I, Fukuhara T, Murakami M, Teshima T. SARS-CoV-2 Omicron detection by antigen tests
using saliva. J Clin Virol Plus. 2022; 2: 100109.
151. Saito R, Kawamoto Y, Nishida M, Iwai T, Kikuchi Y, Yokota I, Takagi R, Yamamura T, Ito K, Harada
K, Yuki S, Komatsu Y, Sakamoto N. Usefulness of ultrasonography and elastography in diagnosing
oxaliplatin-induced sinusoidal obstruction syndrome. Int J Clin Oncol. 2022; 27: 1780-1790.
150. Kawae Y, Matsuoka M, Onodera T, Yokota I, Iwasaki K, Hishimura R, Suzuki Y, Kondo E, Iwasaki
N. Liver metastasis in soft tissue sarcoma at initial presentation J Surg Oncol. 2022; 126: 1074-1079.
149. Tsuchida KI, Taneda S, Yokota I, Okada K, Kurihara Y, Yokoyama H, Iwamoto M, Yamazaki K,
Ishigaki Y, Manda N, Maegawa H; Japan Diabetes Clinical Data Management Study Group (JDDM
study group). The renoprotective effect of once-weekly GLP-1 receptor agonist dulaglutide on progression of nephropathy in Japanese patients with type 2 diabetes and moderate to severe chronic kidneydisease (JDDM67). J Diabetes Investig. 2022; 13: 1834-1841.
148. Yoshimura M, Fujieda Y, Sugawara M, Kono M, Kato M, Yokota I, Amengual O, Ito YM, Atsumi T.
Disease activity as a risk factor for venous thromboembolism in rheumatoid arthritis analysed using
time-averaged DAS28CRP: a nested case-control study. Rheumatol Int. 2022; 42: 1939-1946.
147. Takegami M, Ushigome E, Hata S, Yoshimura T, Kitagawa N, Hasegawa G, Tanaka T, Ohnishi M,
Tsunoda S, Yokota I, Ushigome H, Asano M, Hamaguchi M, Yamazaki M, Fukui M. Home-measured
pulse pressure is a predictor of cardiovascular disease in type 2 diabetes: The KAMOGAWA-HBP
study. Nutr Metab Cardiovasc Dis. 2022; 32: 2330-2337.
146. Morino S, Hirata H, Matsumoto D, Yokota I, Aoyama T. Patterns of premenstrual syndrome incollegiate women: A cross-sectional study. Medicine (Baltimore). 2022; 101: e30186.
145. Nakamura J, Tsujino I, Ohira H, Nakaya T, Sugimoto A, Sato T, Watanabe T, Suzuki M, Kato M,
Yokota I, Konno S. VariousfFactors contributing to death among patients with different types of
pulmonary hypertension: a retrospective pilot study from a single tertiary center. Respir Investig.
2022; 60: 647-657.
144. Akutsu T, Yokota I, Watanabe K, Toyomane K, Yamagishi T, Sakurada K. Precise and comprehensive determination of multiple body fluids by applying statistical cutoff values to a multiplex reverse
transcription-PCR and capillary electrophoresis procedure for forensic purposes. Leg Med(Tokyo).
2022; 58: 102087.
143. Sugawara M, Fujieda Y, Noguchi A, Tanimura S, Shimizu Y, Nakagawa I, Yoshimura M, Abe N,
Kono M, Kato M, Oku K, Amengual O, Yokota I, Takahashi H, Atsumi T. Prediction of the intolerance or non-responder to Janus kinase inhibitors in patients with rheumatoid arthritis: a preliminary
retrospective study with integrative cluster analysis. Clin Exp Rheumatol. 2022; 40: 1674-1680.
142. Miya A, Nakamura A, Yokota I, Cho KY, Kameda H, Nomoto H, Takase T, Omori K, Ono M, Nagai
S, Taneda S, Miyoshi H, Atsumi T. The agreement between measured HbA1c and optimized target
HbA1c based on the Dementia Assessment Sheet for Community-based Integrated Care System 8-items(DASC-8): A cross-sectional study of elderly patients with diabetes. Geriatr Gerontol Int. 2022; 22:560-567.
141. Kanbayashi Y, Sakaguchi K, Ishikawa T, Tabuchi Y, Takagi R, Yokota I, Katoh N, Takayama K,
Taguchi T. Predictors of the development of nab-paclitaxel-induced peripheral neuropathy in breast
cancer patients: post hoc analysis of a prospective, phase II, self-controlled clinical trial. Med Oncol.
2022; 39: 153.

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140. Uchinami Y, Katoh N, Suzuki R, Kanehira T, Tamura M, Takao S, Matsuura T, Miyamoto N, Fujita
Y, Koizumi F, Taguchi H, Yasuda K, Nishioka K, Yokota I, Kobashi K, Aoyama H. A study on
predicting cases that would benefit from proton beam therapy in primary liver tumors of less than orequal to 5 cm based on the estimated incidence of hepatic toxicity. Clin Transl Radiat Oncol. 2022;
35: 70-75.
139. Matsuoka M, Onodera T, Yokota I, Iwasaki K, Hishimura R, Suzuki Y, Iwata A, Kondo E, Iwasaki N.
Does primary tumor resection in patients with metastatic primary mobile vertebral column sarcoma
improve the survivals? World Neurosurg. 2022; 163: e647-e654.
138. Ito K, Yuki S, Nakatsumi H, Kawamoto Y, Harada K, Nakano S, Saito R, Ando T, Sawada K, Yagisawa M, Ishiguro A, Dazai M, Iwanaga I, Hatanaka K, Sato A, Matsumoto R, Shindo Y, Tateyama
M, Muranaka T, Katagiri M, Yokota I, Sakata Y, Sakamoto N, Komatsu Y. Multicenter, prospective, observational study of chemotherapy-induced dysgeusia in gastrointestinal cancer. Support Care
Cancer. 2022; 30: 5351-5359.
137. Kakutani N, Yokota T, Fukushima A, Obata Y, Ono T, Sota T, Kinugasa Y, Takahashi M, Matsuo H,
Matsukawa R, Yoshida I, Kakinoki S, Yonezawa K, Himura Y, Yokota I, Yamamoto K, TsuchihashiMakaya M, Kinugawa S. Impact of citrus fruit intake on the mental health of patients with chronic
heart failure. J Cardiol. 2022; 79: 719-726.
136. Nakano S, Kawamoto Y, Yuki S, Harada K, Miyagishima T, Sogabe S, Dazai M, Sato A, Ishiguro
A, Nakamura M, Kajiura S, Takahashi Y, Tateyama M, Hatanaka K, Tsuji Y, Sasaki T, Shindo Y,
Kobayashi T, Yokota I, Sakamoto N, Sakata Y, Komatsu Y. Study protocol of the HGCSG1803: aphase II multicentre, non-randomised, single-arm, prospective trial of combination chemotherapy withoxaliplatin, irinotecan and S-1 (OX-IRIS) as first-line treatment for metastatic or relapsed pancreaticcancer. BMJ Open. 2022; 12: e048833.
135. Kitagawa N, Ushigome E, Kitagawa N, Ushigome H, Yokota I, Nakanishi N, Hamaguchi M, Asano M,
Yamazaki M, Fukui M. Diabetic nephropathy ameliorated in patients with normal home blood pressurecompared to those with isolated high home systolic blood pressure: A 5-year prospective cohort study
among patients with type 2 diabetes mellitus. Diab Vasc Dis Res. 2022; 19: 14791641221098193.
134. Shima H, Nakaya T, Tsujino I, Nakamura J, Sugimoto A, Sato T, Watanabe T, Ohira H, Suzuki
M, Kato M, Yokota I, Konno S. Accuracy of Swan–Ganz catheterization-based assessment of rightventricular function: Validation study using high-fidelity micromanometry-derived values as reference.
Pulm Circ. 2022; 12: e12078.
133. Otsuka S, Hiraoka K, Suzuoki M, Ujiie H, Kato T, Yokota I, Yonezawa K, Oguma K, Iwashiro N, Kato
M, Ohara M. Antibody responses induced by the BNT162b2 mRNA COVID-19 vaccine in healthcare
workers in a single community hospital in Japan. J Infect Chemother. 2022; 28: 539-542.
132. Ike S, Matsuoka M, Onodera T, Yokota I, Iwasaki K, Hishimura R, Suzuki Y, Kondo E, Iwasaki N.
Primary malignant osseous neoplasms in the hand Anticancer Res. 2022; 42: 1635-1640.
131. Shimizu K, Tanabe N, Oguma A, Kimura H, Suzuki M, Yokota I, Makita H, Sato S, Hirai T, Nishimura
M, Konno S; Hi-CARAT investigators. Parenchymal destruction in asthma: Fixed airflow obstruction
and lung function trajectory. J Allergy Clin Immunol. 2022; 149: 932-942.e8.
130. Ishi Y, Harada T, Kameda H, Okada H, Yokota I, Harada T, Kameda H, Okada H, Yokota I, Okamoto
M, Sawaya R, Motegi H, Yamaguchi S, Terasaka S, Kudo K, Fujimura M. Variations and natural historyof primary intraparenchymal lesions associated with neurofibromatosis type 2. Neuroradiology. 2022;
64: 393-396.

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129. Aikawa K, Yokota I, Maeda Y, Morimoto Y. Evaluation of sensory loss obtained by modifiedthoracoabdominal nerves block through perichondrial approach in patients undergoing gynecologicallaparoscopic surgery: a prospective observational study. Reg Anesth Pain Med. 2022; 47: 134-135.
128. Iwai K, Ushigome E, Okada K, Yokota I, Majima S, Nakanishi N, Hashimoto Y, Okada H, Senmaru
T, Hamaguchi M, Asano M, Yamazaki M, Fukui M. Usefulness of aerobic exercise for home bloodpressure control in patients with diabetes: randomized crossover trial. J Clin Med. 2022; 11: 650.
127. Takahashi T, Okamoto T, Yokota I, Sato Y, Hayashi A, Ueda Y, Aoyagi H, Ueno M, Kobayashi
N, Uetake K, Nakanishi M, Ariga T. The effect of rituximab on the quality of life of children withrefractory nephrotic syndrome. Pediatr Int. 2022; 64: 95-101.
126. Omote K, Yokota I, Nagai T, Sakuma I, Nakagawa Y, Kamiya K, Iwata H, Miyauchi K, Ozaki Y,
Hibi K, Hiro T, Fukumoto Y, Mori H, Hokimoto S, Ohashi Y, Ohtsu H, Ogawa H, Daida H, Iimuro S,
Shimokawa H, Saito Y, Kimura T, Matsuzaki M, Nagai R, Anzai T. REAL-CAD study investigators.
high-density lipoprotein cholesterol and cardiovascular events in patients with stable coronary arterydisease treated with statins: an observation from the REAL-CAD Study. J Atheroscler Thromb. 2022;
29: 50-68.
125. Kinoshita F, Yokota I, Mieno H, Ueta M, Bush J, Kinoshita S, Sueki H, Asada H, Morita E, Fukushima
M, Sotozono C, Teramukai S; Japanese Research Committee on Severe Cutaneous Adverse Reaction.
Multi-state model for predicting ocular progression in acute Stevens-Johnson syndrome/toxic epidermal
necrolysis. PLoS One. 2021;16:e0260730.
124. Matsuoka M, Onodera T, Yokota I, Iwasaki K, Matsubara S, Hishimura R, Kondo E, Iwasaki N.
Surgical resection of primary tumor in the extremities improves survival for metastatic soft-tissue
sarcoma patients: a population-based study of the SEER database. Clin Transl Oncol. 2021; 41:
5611–5616.
123. Watanabe M, Yokoshiki H, Noda T, Yokota I, Nitta T, Aizawa Y, Ohe T, Kurita T. Electrical storm
as an independent mortality risk in patients with preserved or moderately reduced left ventricularfunction: Results from a Japanese nationwide registry. Int Heart J. 2021; 62: 1249–1256.
122. Itoga R, Matsuoka M, Onodera T, Yokota I, Iwasaki K, Matsubara S, Hishimura R, Suzuki Y, Iwata
A, Kondo E, Iwasaki N. Brain metastasis in soft tissue sarcoma at initial presentation. Anticancer
Res. 2021; 41: 5611–5616.
121. Kawamura T, Sakiyama N, Tanaka K, Yokota I, Uno K, Yasuda K. Ischemic colitis caused by bowel
preparation for colonoscopy.Gastroenterology Res. 2021; 14: 296-303.
120. Nakamura Y, Hieda O, Yokota I, Teramukai S, Sotozono C, Kinoshita S. Comparison of myopia
progression between children wearing three types of orthokeratology lenses and children wearing singlevision spectacles. Jpn J Opthalmol. 2021; 65: 632–643.
119. Yokota I, Shane PY, Teshima T. Logistic advantage of two-step screening strategy for SARS-CoV-2
at airport quarantine. Travel Med Infect Dis. 2021; 43: 102127.
118. Yokota I, Sakurazawa T, Sugita J, Iwasaki S, Yasuda K, Yamashita N, Fujisawa S, Nishida M, Konno
S, Teshima T. Performance of qualitative and quantitative antigen tests for SARS-CoV-2 using saliva.
Infect Dis Rep. 2021; 13: 742–747.
117. Yokota I, Shane PY, Okada K, Unoki Y, Yang Y, Inao T, Sakamaki K, Iwasaki S, Hayasaka K, Sugita
J, Nishida M, Fujisawa S, Teshima T. Mass screening of asymptomatic persons for SARS-CoV-2 using
saliva. Clin Infect Dis. 2021; 73: e559–e565.

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9116. Takei N, Suzuki M, Tanabe N, Oguma A, Shimizu K, Kimura H, Makita H, Sato S, Hirai T, Yokota
I, Konno S, Nishimura M. Combined assessment of pulmonary arterial enlargement and coronary
calcification predicts the prognosis of patients with chronic obstructive pulmonary disease. Respir
Med. 2021; 185: 106520.
115. Yokota I, Shane PY, Okada K, Unoki Y, Yang Y, Iwasaki S, Fujisawa S, Nishida M, Teshima T. A
novel strategy for SARS-CoV-2 mass-screening using quantitative antigen testing of saliva: a diagnostic
accuracy study. Lancet Microbe. 2021; 2: e397–e404.
114. Yamada T, Takao S, Koyano H, Nihongi H, Fujii Y, Hirayama S, Miyamoto N, Matsuura T, Umegaki
K, Katoh N, Yokota I, Shirato H, Shimizu S. Validation of dose distribution for liver tumors treatedwith real-time-image gated spot-scanning proton therapy by log data based dose reconstruction. J
Radiat Res. [Epub ahead of print]
113. Oyabu C, Ushigome E, Ono Y, Kobayashi A, Hashimoto Y, Sakai R, Iwase H, Okada H, Yokota I,
Tanaka T, Fukui M. Randomized controlled trial of simple salt reduction instructions by physician forpatients with type 2 diabetes consuming excessive salt. Int J Environ Res Public Health. 2021; 18:
6913.
112. Nishida M, Sugita J, Takahashi S, Iwai T, Sato M, Kudo Y, Omotehara S, Horie T, Sakano R, Shibuya
H, Yokota I, Iguchi A, Teshima T. Refined ultrasonographic criteria for sinusoidal obstruction syndrome after hematopoietic stem cell transplantation. Int J Hematol. 2021; 114: 94-101.
111. Matsuoka M, Okamoto M, Soma T, Yokota I, Arai R, Onodera T, Kondo E, Iwasaki N, Hiraga H.
Impact of smoking history on pulmonary metastasis-free survival in patients with soft-tissue sarcoma.
Cancer Diagn Progn. 2021; 1: 89-94.
110. Iwasaki K, Kondo E, Matsubara S, Matsuoka M, Endo K, Yokota I, Onodera T, Iwasaki N. Effectof high tibial osteotomy on the distribution of subchondral bone density across the proximal tibial
articular surface of the knee with medial compartment osteoarthritis. Am J Sports Med. 2021; 49:
1561–1569.
109. Kitagawa N, Kitagawa N, Ushigome E, Ushigome H, Yokota I, Nakanishi N, Hamaguchi M, Asano M,
Yamazaki M, Fukui M. Impact of isolated high home systolic blood pressure and diabetic nephropathy
in patients with type 2 diabetes mellitus: A 5-Year prospective cohort study. J Clin Med. 2021; 10:1929.
108. Yasuda K, Minatogawa H, Dekura Y, Takao S, Tamura M, Tsushima N, Suzuki T, Kano S, Mizumachi
T, Mori T, Nishioka K, Shido M, Katoh N, Taguchi H, Fujima N, Onimaru R, Yokota I, Kobashi K,
Shimizu S, Homma A, Shirato H, Aoyama H. Analysis of acute-phase toxicities of intensity-modulated
proton therapy using a model-based approach in pharyngeal cancer patients. J Radiat Res. 2021; 62:
329–337.
107. Obata Y, Kakutani N, Kinugawa S, Fukushima A, Yokota T, Takada S, Ono T, Sota T, Kinugasa Y,
Takahashi M, Matsuo H, Matsukawa R, Yoshida I, Yokota I, Yamamoto K, Tsuchihashi-Makaya M.
Impact of inadequate calorie intake on mortality and hospitalization in stable patients with chronic
heart failure. Nutrients. 2021; 13:874.
106. Ushigome E, Kitagawa N, Kitagawa N, Tanaka T, Hasegawa G, Ohnishi M, Tsunoda S, Ushigome
H, Yokota I, Nakamura N, Asano M, Hamaguchi M, Yamazaki M, Fukui M. Predictive powerof home blood pressure measurement for cardiovascular outcomes in patients with type 2 diabetes:
KAMOGAWA-HBP study. Hypertens Res. 2021; 44: 348-354.
105. Yokota I, Hattori T, Shane PY, Konno S, Nagasaka A, Takeyabu K, Fujisawa S, Nishida M, Teshima T.
Equivalent SARS-CoV-2 viral loads between nasopharyngeal swab and saliva in symptomatic patients.
Sci Rep. 2021; 11:4500

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104. Minatogawa H, Yasuda K, Dekura Y, Takao S, Matsuura T, Yoshimura T, Suzuki R, Yokota I, Fujima
N, Onimaru R, Shimizu S, Aoyama H, Shirato H. Potential benefits of adaptive intensity-modulated
proton therapy in nasopharyngeal carcinomas. J Appl Clin Med Phys. 2021; 22: 174-183.
103. Yamamoto M, Mori T, Toki T, Itosu Y, Kubo Y, Yokota I, Morimoto Y. The relationships of cerebral and somatic oxygen saturation with physiological parameters in pediatric cardiac surgery withcardiopulmonary bypass: analysis using the random-effects model. Pediatr Cardiol. 42: 370–378
102. Taki K, Yokota I, Fukumoto T, Iwasaki S, Fujisawa S, Takahashi M, Negishi S, Hayasaka K, SatoK, Oguri S, Nishida M, Sugita J, Konno S, Saito T, Teshima T. SARS-CoV-2 detection by fluorescence loop-mediated isothermal amplification with and without RNA extraction. J Infect Chemother.
2021;27:410–412.
101. Iwai T, Nishida M, Sugita J, Kudo Y, Takasugi R, Yokota I, Takagi R, Shibuya H, Takahashi S,
Teshima T. Reliability of an ultrasonographical scoring system for sinusoidal obstruction syndrome/ veno-occlusive disease diagnosis in patients with hematopoietic stem cell transplantation. J Med
Ultrasonics. 2021; 48: 45–52.
100. Nakamura H, Fujieda Y, Tarumi M, Kitakawa H, Hisada R, Nakagawa I, Noguchi A, Kurita T, Kataoka
H, Kasahara H, Amasaki Y, Yokota I, Atsumi T. Calcineurin inhibitors for adult-onset Still’s disease:a multicentre retrospective cohort study. Clin Exp Rheumatol. 2020; 38: 11–16.
99. Iwai K, Ushigome E, Yokota I, Majima S, Nakanishi N, Hashimoto Y, Okada H, Senmaru T, Hamaguchi M, Asano M, Yamazaki M, Fukui M. Usefulness of exercise for home blood pressure control inpeople with diabetes: A study protocol for a crossover randomized controlled trial. Diabetes Metab
Syndr Obes. 2020; 13: 4747–4753.
98. Chinen Y, Tanba K, Takagi R, Uchiyama H, Uoshima N, Shimura K, Fuchida SI, Kiyota M, Nakao M,
Tsukamoto T, Shimura Y, Kobayashi T, Horiike S, Wada K, Shimazaki C, Kaneko H, Kobayashi Y,
Taniwaki M, Yokota I, Kuroda J; Kyoto Clinical Hematology Study Group investigators. Second primary malignancy after rituximab-containing immunochemotherapy for diffuse large B cell lymphoma.
Leuk Lymphoma. 2020; 61: 3378–3386.
97. Fujioka A, Yanishi K, Shoji K, Hori Y, Kawamata H, Yukawa A, Yokota I, Teramukai S, YamadaA, Matoba S. Therapeutic angiogenesis using bone marrow-derived mononuclear cell implantation forpatients with critical limb-threatening ischemia caused by thromboangiitis obliterans - study protocol
for a multicenter prospective interventional trial. Circ Rep. 2020 Sep 15;2:630-634.
96. Hane Y, Tsuchikawa T, Nakamura T, Hatanaka KC, Saito T, Tanaka K, Nakanishi Y, Asano T, Noji T,
Okamura K, Shichinohe T, Yokota I, Hatanaka Y, Hirano S. Immunological gene signature associatedwith the tumor microenvironment of pancreatic cancer after neoadjuvant chemotherapy. Pancreas.
2020; 49: 1240–1245.
95. Abe T, Yokota T, Fukushima A, Kakutani N, Katayama T, Shirakawa R, Maekawa S, Nambu H, Obata
Y, Yamanashi K, Nakano I, Takada S, Yokota I, Okita K, Kinugawa S, Anzai T. Type 2 diabetes is
an independent predictor of lowered peak aerobic capacity in heart failure patients with non-reduced
or reduced left ventricular ejection fraction. Cardiovasc Diabetol. 2020;19:142.
94. Watanabe-Hosomi A, Mizuta I, Koizumi T, Yokota I, Mukai M, Hamano A, Kondo M, Fujii A,
Matsui M, Matsuo K, Ito K, Teramukai S, Yamada K, Nakagawa M, Mizuno T. Effect of lomerizinehydrochloride on preventing strokes in patients with cerebral autosomal dominant arteriopathy with
subcortical infarcts and leukoencephalopathy. Clin Neuropharmacol. 2020; 43: 146–150
93. Noguchi A, Hosokawa K, Amaya F, Yokota I. Factors related to memory absence and delusional
memories in patients in intensive care units managed with light sedation. Intensive Crit Care Nurs.
2020;59:102830.

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92. Miyake M, Matsuyama H, Teramukai S, Kinoshita F, Yokota I, Matsumoto H, Shimada K, Kinjyo M, Shimokama T, Okumura K, Yomenori M, Enokida H, Nakagawa M, Nakai Y, Fujimoto K;
Nishinihon Uro-oncology Extensive Collaboration group. A new risk stratification model for intravesical recurrence, disease progression, and cancer-specific death in patients with non-muscle invasive
bladder cancer: the J-NICE risk tables. Int J Clin Oncol. 2020;25:1364–76.
91. Iwasaki K, Inoue M, Kasahara Y, Tsukuda K, Kawahara H, Yokota I, Kondo E, Iwasaki N, Yasuda
K. Inclination of Blumensaat’s line influences on the accuracy of the quadrant method in evaluation foranterior cruciate ligament reconstruction. Knee Surg Sports Traumatol Arthrosc. 2020;28: 1885–1893.
90. Ohara M, Suda G, Kimura M, Maehara O, Shimazaki T, Shigesawa T, Suzuki K, Nakamura A, Kawagishi N, Nakai M, Sho T, Natsuizaka M, Morikawa K, Ogawa K, Kobayashi T, Uebayashi M, Takagi R,
Yokota I, Shimamura T, Sakamoto N. Analysis of the optimal psoas muscle mass index cut-off values,
as measured by computed tomography, for the diagnosis of loss of skeletal muscle mass in Japanesepeople. Hepatol Res. 2020; 50:715–725.
89. Yoshikawa Y, Ueta M, Fukuoka H, Inatomi T, Yokota I, Teramukai S, Yokoi N, Kinoshita S, Tajiri
K, Ikeda T, Sotozono C. Long-term progression of ocular surface disease in Stevens-Johnson syndrome
and toxic epidermal necrolysis. Cornea. 2020; 39: 745–753.
88. Akutsu T, Yokota I, Watanabe K, Sakurada K. Development of a multiplex RT-PCR assay andstatistical evaluation of its use in forensic identification of vaginal fluid. Leg Med(Tokyo). 2020; 45:
101715.
87. Kato M, Kaneko Y, Tanaka Y, Inoo M, Kobayashi-Haraoka H, Amano K, Miyata M, Murakawa Y,
Yasuoka H, Hirata S, Nagasawa H, Tanaka E, Miyasaka N, Yamanaka H, Yamamoto K, Yokota I,
Atsumi T, Takeuchi T. Predictive value of serum amyloid A levels for requirement of concomitant
methotrexate in tocilizumab initiation: A post-hoc analysis of the SURPRISE study. Mod Rheumatol.
2020; 30: 442–449.
86. Kawamura T, Takeuchi Y, Yokota I, Takagaki N. Indications for cold polypectomy stratified by thecolorectal polyp size: a systematic review and meta-Analysis. J Anus Rectum Colon. 2020;4:67–78.
85. Kawamura T, Inoue T, Shinomiya R, Sakai H, Amamiya K, Sakiyama N, Shirakawa A, Okada Y,
Sanada K, Nakase K, Mandai K, Suzuki A, Kamaguchi M, Morita A, Nishioji K, Tanaka K, Uno K,
Yokota I, Kobayashi M, Yasuda K. Significance of fecal hemoglobin concentration for predicting riskof colorectal cancer after colonoscopy. JGH Open. 2020;4:898–902.
84. Itoi M, Kitazawa K, Yokota I, Wakimasu K, Cho Y, Nakamura Y, Hieda O, Teramukai S, Kinoshita
S, Sotozono C. Anterior and posterior ratio of corneal surface areas: A novel index for detecting earlystage keratoconus. PLoS One. 2020;15:e0231074.
83. Fujikawa K, Teramukai S, Yokota I, Daimon T. A Bayesian basket trial design that borrows information across strata based on the similarity between the posterior distributions of the response probability.
Biom J. 2020;62:330–338.
82. Kida T, Tanaka T, Yokota I, Tamagaki K, Sagawa T, Kadoya M, Yamada T, Fujioka K, Wada
M, Kohno M, Hiraoka N, Omoto A, Fukuda W, Kawahito Y. Association between preexisting lunginvolvements and the risk of diffuse alveolar hemorrhage in patients with microscopic polyangiitis: amulti-center retrospective cohort study. Mod Rheumatol. 2020;30:338–344.
81. Wakimasu K, Kitazawa K, Kayukawa K, Yokota I, Inatomi T, Hieda O, Sotozono C, Kinoshita S. Fiveyear follow-up outcomes after Descemet’s stripping automated endothelial keratoplasty: a retrospective
study. BMJ Open Ophthalmol. 2020; 5: e000354.

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80. Kanbayashi Y, Sakaguchi K, Ishikawa T, Ouchi Y, Nakatsukasa K, Tabuchi Y, Kanehisa F, Hiramatsu
M, Takagi R, Yokota I, Katoh N, Taguchi T. Comparison of the efficacy of cryotherapy and compression therapy for preventing nanoparticle albumin-bound paclitaxel-induced peripheral neuropathy: aprospective self-controlled trial. Breast. 2020; 49: 219–224.
79. Ushigome E, Kitagawa N, Kitae A, Kimura T, Iwai K, Oyabu C, Ushigome H, Yokota I, Hamaguchi M,
Asano M, Yamazaki M, Fukui M. Seasonal variation in home blood pressure and its relationship withroom temperature in patients with type 2 diabetes. Diab Vasc Dis Res. 2020; 17:1479164119883986.
78. Kaneshita S, Kida T, Yokota I, Nagahara H, Seno T, Wada M, Kohno M, Kawahito Y. Risk factors
for cytomegalovirus disease with cytomegalovirus re-activation in patients with rheumatic disease. Mod
Rheumatol. 2020;30:109–115.
77. Ushigome E, Oyabu C, Shiraishi M, Kitagawa N, Kitae A, Iwai K, Ushigome H, Yokota I, Hamaguchi
M, Yamazaki M, Fukui M. Evaluation of the efficacy of simplified nutritional instructions from physicians on dietary salt restriction for patients with type 2 diabetes mellitus consuming excessive salt:
protocol for a randomized controlled trial. Trials. 2019;20:761.
76. Kitagawa N, Ushigome E, Tanaka T, Hasegawa G, Nakamura N, Ohnishi M, Tsunoda S, Ushigome H,
Yokota I, Kitagawa N, Hamaguchi M, Asano M, Yamazaki M, Fukui M. Isolated high home systolicblood pressure in patients with type 2 diabetes is a prognostic factor for the development of diabetic
nephropathy: KAMOGAWA-HBP study. Diabetes Res Clin Pract. 2019;158:107920.
75. Taniguchi Y, Kitamura A, Ishizaki T, Fujiwara Y, Shinozaki T, Seino S, Mitsutake S, Suzuki H,
Yokoyama Y, Abe T, Ikeuchi T, Yokota I, Matsuyama Y, Shinkai S. Association of trajectories ofcognitive function with cause-specific mortality and medical and long-term care costs. Geriatr Gerontol
Int. 2019; 19: 1236–1242.
74. Yamaguchi J, Chinen Y, Takimoto-Shimomura T, Nagata H, Muramatsu A, Kuriyama K, Ohshiro
M, Hirakawa Y, Iwai T, Uchiyama H, Uoshima N, Kaneko H, Nakao M, Tsukamoto T, Shimura
Y, Kobayashi T, Horiike S, Yokota I, Kuroda J; KOTOSG Investigators. Prediction of delayed
platelet engraftment after autologous stem cell transplantation for B-cell non-Hodgkin lymphoma.
Leuk Lymphoma. 2019; 60:3434–3441.
73. Yamauchi Y, Nakamura A, Takahashi K, Takase T, Yamamoto C, Yokota I, Atsumi T, Miyoshi H.
Factors with remission of fatty liver in patients with type 2 diabetes treated with ipragliflozin. Endocr
J. 2019; 66:995-1000.
72. Takai S, Nakanishi N, Yokota I, Imai K, Yamada A, Kawasaki T, Okada T, Sawada T, Fujita H,
Matoba S. Clot regression effects of rivaroxaban in the treatment of venous thromboembolism inpatients with cancer (CRERIT-VTE cancer): study protocol. BMJ Open. 2019;9:e031698.
71. Iwai K, Ushigome E, Matsumoto S, Kitagawa N, Ushigome H, Yokota I, Asano M, Hamaguchi M,
Yamazaki M, Fukui M. Home blood pressure is associated with cognitive impairment among elderly
patients with type 2 diabetes: KAMOGAWA-HBP study. Diab Vasc Dis Res. 2019;16:506–512.
70. Ushigome E, Oyabu C, Iwai K, Kitagawa N, Kitae A, Kimura T, Yokota I, Ushigome H, Hamaguchi
M, Asano M, Yamazaki M, Fukui M. Effects of dietary salt restriction on home blood pressure indiabetic patients with excessive salt intake: a pilot study. J Clin Biochem Nutr. 2019;65:252–257.
69. Okamura T, Ushigome E, Kitagawa N, Oyabu C, Tanaka T, Hasegawa G, Nakamura N, Ohnishi M,
Tsunoda S, Ushigome H, Yokota I, Hamaguchi M, Asano M, Yamazaki M, Fukui M. Maximum
morning home systolic blood pressure is an indicator of the development of diabetic nephropathy: The
KAMOGAWA-HBP study. J Diabetes Investig. 2019;10:1543–1549.

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68. Iehara T, Yoneda A, Yokota I, Takahashi H, Teramukai S, Kamijyo T, Nakazawa A, Takimoto T,
Kikuta A, Yagyu S, Ikeda H, Nakagawara A, Tajiri T, Japan Childhood Cancer Group Neuroblastoma
Committee (JNBSG). Results of a prospective clinical trial JN-L-10 using image-defined risk factors
to inform surgical decisions for children with low-risk neuroblastoma disease: A report from the Japan
Children’s Cancer Group Neuroblastoma Committee. Pediatr Blood Cancer. 2019; 66:e27914
67. Shimizu M, Amaya F, Kinoshita M, Yamasaki M, Yokota I, Sawa T. Reduction of the rocuroniuminduced withdrawal reflex by MR13A10A, a generic rocuronium with a novel solution: A randomized,
controlled study. PLoS One. 2019;14:e0223947.
66. Taniguchi Y, Kitamura A, Kaito S, Yokoyama Y, Yokota I, Shinozaki T, Seino S, Murayama H,
Matsuyama Y, Ikeuchi T, Fujiwara Y, Shinkai S. Albumin and hemoglobin trajectories and incident
disabling dementia in community-dwelling older Japanese. Dement Geriatr Cogn Disord. 2019; 47:
233–242.
65. Zen Y, Chiyonobu T, Yuge M, Yokota I, Morimoto M, Teramukai S, Hosoi H. Gender differences inoccurrence of behavioral and emotional problems at the lower grades of elementary school: association
with developmental and behavioral characteristics at 5years. Brain Dev. 2019;41:760–768.
64. Nakao R, Konishi E, Fujiwara H, Otsuji E, Yokota I, Urata Y, Yanagisawa A. Residual cancer
volume predicts clinical outcome in patients with esophageal squamous cell carcinoma after neoadjuvant
chemotherapy. Int J Surg Pathol. 2019;27:713-721.
63. Sagawa T, Kida T, Inaba T, Yokota I, Sagawa R, Kasahara A, Kaneshita S, Inoue T, Nagahara H,
Fujioka K, Wada M, Kohno M, Kawahito Y. Utility of coagulation markers for the prediction of rapidly
progressive interstitial lung disease in patients with dermatomyositis. Lung. 2019;197:437–442.
62. Sakaguchi K, Ono H, Nakatsukasa K, Ishikawa T, Hasegawa Y, Takahashi M, Niikura N, Koizumi K,
Sakurai T, Shigematsu H, Takahashi S, Taira S, Suzuki M, Narui K, Miura D, Yamada K, Yoshimura
M, Shioya H, Konishi E, Yokota I, Imai K, Fujikawa K, Taguchi T; Collaborative Study Groupof Scientific Research of the Japanese Breast Cancer Society. Efficacy of denosumab for restoring
normal bone mineral density in women receiving adjuvant aromatase inhibitors for early breast cancer.
Medicine (Baltimore). 2019;98:e16770
61. Morio K, Maeda I, Yokota I, Niki K, Murata T, Matsumura Y, Uejima E. Risk factors for polypharmacy in elderly patients with cancer pain. Am J Hosp Palliat Care. 2019; 36:598–602.
60. Tsuboi H, Yokota I, Miyamori D, Akasaka Y, Yamada A, Ikegaya H. Age estimation based on visualparameters of the skin of cadavers. Skin Res Technol. 2019;25:532–537.
59. Mihara Y, Kado H, Yokota I, Shiotsu Y, Sonomura K, Kusaba T, Hatta T, Matoba S, Tamagaki K.
Rapid weight loss with dietary salt restriction in hospitalized patients with chronic kidney disease. Sci
Rep. 2019;9:8787.
58. Sowa Y, Yokota I, Fujikawa K, Morita D, Taguchi T, Numajiri T. Objective evaluation of fat tissue
induration after breast reconstruction using a deep inferior epigastric perforator (DIEP) flap. J Plast
Surg Hand Surg. 2019;53:125–129.
57. Yokota J, Fukutani N, Nin K, Yamanaka H, Yasuda M, Tashiro Y, Matsushita T, Suzuki Y, Yokota
I, Teramukai S, Aoyama T. Association of low back pain with presenteeism in hospital nursing staff.
J Occup Health. 2019;61:219–226.
56. Shinomoto M, Kasai T, Tatebe H, Kondo M, Ohmichi T, Morimoto M, Chiyonobu T, Terada N,
Allsop D, Yokota I, Mizuno T, Tokuda T. Plasma neurofilament light chain: A potential prognostic
biomarker of dementia in adult Down syndrome patients. PLoS One. 2019;14:e0211575.

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55. Kaibori M, Yoshii K, Yokota I, Hasegawa K, Nagashima F, Kubo S, Kon M, Izumi N, Kadoya M,
Kudo M, Kumada T, Sakamoto M, Nakashima O, Matsuyama Y, Takayama T, Kokudo N; Liver
Cancer Study Group of Japan. Impact of advanced age on survival in patients undergoing resection ofhepatocellular carcinoma: report of a Japanese nationwide survey. Ann Surg. 2019; 269:692–699.
54. Noguchi A, Inoue T, Yokota I. Promoting a nursing team’s ability to notice intent to communicate in lightly sedated mechanically ventilated patients in an Intensive Care Unit: an action researchstudy.Intensive Crit Care Nurs. 2019; 51: 64–72.
53. Goto M, Sakai K, Yokota H, Kiba M, Yoshida M, Imai H, Weiland E, Yokota I, Yamada K. Diagnostic
performance of initial enhancement analysis using ultra-fastdynamic contrast-enhanced MRI for breast
lesions. Eur Radiol. 2019;29:1164-1174.
52. Yokota I, Matsuyama Y. Dynamic prediction of repeated events data based on landmarking model:
application to colorectal liver metastases data. BMC Med Res Methodol. 2019;30:31.
51. Yasuda H, Kataoka K, Takeyama Y, Takeda K, Ito T, Mayumi T, Isaji S, Mine T, Kitagawa M,Kiriyama
S, Sakagami J, Masamune A, Inui K, Hirano K, Akashi R, Yokoe M, Sogame Y, Okazaki K, Morioka C,
Kihara Y, Kawa S, Tanaka M, Andoh A, Kimura W, Nishimori I, Furuse J, Yokota I, Shimosegawa
T. Usefulness of urinary trypsinogen-2 and trypsinogen activation peptide in acute pancreatitis: A
multicenter study in Japan. World J Gastroenterol. 2019; 25: 107-117.
50. Kunikane H, Yokota I, Katakami N, Takeda K, Takayama K , Sawa T, Saito H, Harada M, Yokota S,
Ando K, Saito Y, Ohashi Y, Eguchi K. Prospective analysis of the association between skeletal-related
events and quality of life in patients with advanced lung cancer (CSP-HOR13). Oncol Lett. 2019; 17:1320-1326.
49. Miyake H, Sakagami J, Yasuda H, Sogame Y, Kato R, Suwa K, Dainaka K, Takata T, Yokota I, ItohY. Association of fatty pancreas with pancreatic endocrine and exocrine function. PLOS One. 2018;
13: e0209448.
48. Kaibori M, Yoshii K, Yokota I. Reply to ”Relative survival instead of overall survival should be usedas outcome when analyzing the effect of age after treatment of hepatocellular carcinoma”. Ann Surg.
2018; 268:e76-e77.
47. Toyama T, Yoshimura A, Hayashi T, Kobatashi N, Saito K, Tsuneizumi M, Sawaki M, Hattori M,
Nakada T, Yokota I, Iwata H. A randomized phase II study evaluating pyridoxine for the preventionof hand-foot syndrome associated with capecitabine therapy for advanced or metastatic breast cancer.
Breast Cancer. 2018; 25: 729-735.
46. Yamazaki S, Numata S, Inoue T, Itatani K, Morimoto K, Ohira S, Manabe K, Yokota I, Yaku H.
Impact of right ventricular volume and function evaluated using cardiovascular magnetic resonanceimaging on outcomes after surgical ventricular reconstruction. Eur J Cardiothorac Surg. 2018. 2018;
54: 867-874.
45. Kawamura T, Takeuchi Y, Asai S, Yokota I, Akamine E, Kato M, Akamatsu T, Tada K, Komeda Y,
Iwatate M, Kawakami K, Nishikawa M, Watanabe D, Yamauchi A, Fukata N, Shimatani M, Ooi M,
Fujita K, Sano Y, Kashida H, Hirose S, Iwagami H, Uedo N, Teramukai S, Tanaka K. A comparisonof the resection rate for cold and hot snare polypectomy for 4-9 mm colorectal polyps: a multicentre
randomised controlled trial (CRESCENT study). Gut. 2018. 67: 1950-1957.
44. Kitazawa K, Itoi M, Yokota I, Wakimasu K, Cho Y, Nakamura Y, Hieda O, Kinoshita S, Sotozono
C. Involvement of anterior and posterior corneal surface area imbalance in the pathological change of
keratoconus. Sci Rep. 2018; 8:14993.

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43. Okamoto A, Yamasaki M, Yokota I, Mori M, Matsuda M , Yamaguchi Y , Yamakita S, Ueno H,
Sawa T, Taguchi T, Hosokawa T, Amaya F. Classification of acute pain trajectory after breast cancer
surgery identifies patients at risk for persistent pain: a prospective observational study. J Pain Res.
2018; 11: 2197-2206.
42. Kitazawa K, Wakimasu K, Kayukawa K, Yokota I, Inatomi T, Hieda O, Sotozono C, Kinoshita S.
Moderately long-term safety and efficacy of repeat penetrating keratoplasty. Cornea. 2018; 37: 12551259.
41. Hishiki T, Matsumoto K, Ohira M, Kamijo T, Shichino H, Kuroda T, Yoneda A, Soejima T, Nakazawa
A, Takimoto T, Yokota I, Teramukai S, Takahashi H, Fukushima T, Kaneko T, Hara J, Kaneko
M, Ikeda H, Tajiri T, Nakagawara A; Japan Childhood Cancer Group Neuroblastoma Committee(JNBSG).Results of a phase II trial for high-risk neuroblastoma treatment protocol JN-H-07: a reportfrom the Japan Childhood Cancer Group Neuroblastoma Committee (JNBSG). Int J Clin Oncol. 2018.
2018; 23: 965-973.
40. Katayama K, Imai T, Abe Y, Nawa T, Maeda N, Nakanishi K, Wada H, Fukui K, Ito Y, Yokota I,
Ohkawa K. Number of nodules but not dize of hepatocellular carcinoma can predict refractoriness totransarterial chemoembolization and poor prognosis. J Clin Med Res. 2018; 10: 765-771.
39. Hagiwara N, Watanabe M, Iizuka-Ohashi M, Yokota I, Toriyama S, Sukeno M, Tomosugi M, Sowa Y,
Hongo F, Mikami K, Soh J, Fujito A, Miyashita H, Morioka Y, Miki T, Ukimura O, Sakai T. Mevalonate
pathway blockage enhances the efficacy of mTOR inhibitors with the activation of retinoblastoma
protein in renal cell carcinoma. Cancer Lett. 2018; 431:182-189.
38. Watanabe A, Nakamae T, Sakai Y, Nishida S, Abe Y, Yamada K, Yokota I, Narumoto J. The
detection of white matter alterations in obsessive-compulsive disorder revealed by TRActs Constrainedby UnderLying Anatomy (TRACULA). Neuropsychiatr Dis Treat. 2018; 14: 1635-1643.
37. Kitagawa N, Ushigome E, Matsumoto S, Oyabu C, Ushigome H, Yokota I, Asano M, Tanaka M,
Yamazaki M, Fukui M. Prognostic significance of home pulse pressure for progression of diabetic
nephropathy: KAMOGAWA-HBP study. Hypertens Res. 2018; 41: 363-371.
36. Matsumura-Kimoto Y, Kuroda J, Kaneko H, Kamitsuji Y, Fuchida SI, Nakaya A, Shibayama H,
Uoshima N, Yokota I, Uchiyama H, Yagi H, Kosugi S, Matsui T, Ishikawa J, Matsuda M, Ohta K,
Iida M, Tanaka H, Kobayashi M, Wada K, Shimazaki C, Nomura S, Imada K, Hino M, Matsumura I,
Kanakura Y, Takaori-Kondo A; Kansai Myeloma Forum Investigators. Pomalidomide with or without
dexamethasone for relapsed/refractory multiple myeloma in Japan: a retrospective analysis by the
Kansai Myeloma Forum. Int J Hematol. 2018; 107: 541-550.
35. Ushigome E, Oyabu C, Tanaka T, Hasegawa G, Ohnishi M, Tsunoda S, Ushigome H, Yokota I,
Nakamura N, Oda Y, Asano M, Tanaka M, Yamazaki M, Fukui M. Impact of masked hypertension
on diabetic nephropathy in patients with type II diabetes: a KAMOGAWA-HBP study. J Am Soc
Hypertens. 2018;12:364-371.
34. Ushigome E, Matsumoto S, Oyabu C, Kitagawa N, Tanaka T, Hasegawa G, Ohnishi M, Tsunoda S,
Ushigome H, Yokota I, Nakamura N, Oda Y, Asano M, Tanaka M, Yamazaki M, Fukui M. Prognostic
significance of day-by-day variability of home blood pressure on progression to macroalbuminuria inpatients with diabetes. J Hypertens. 2018; 36: 1068-1075.
33. Kinoshita S, Koizumi N, Ueno M, Okumura N, Imai K, Tanaka H, Yamamoto Y, Nakamura T, Inatomi
T, Bush J, Toda M, Hagiya M, Yokota I, Teramukai S, Sotozono C, Hamuro J. Injection of cultured
cells with ROCK inhibitor for bullous keratopathy. N Engl J Med. 2018;378:995-1003.

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32. Mizuno Y, Tsukamoto T, Kawata E, Uoshima N, Uchiyama H, Yokota I, Maegawa S, Takimoto
T, Tanba K, Matsumura-Kimoto Y, Kuwahara-Ota S, Fujibayashi Y, Yamamoto-Sugitani M, Chinen
Y, Shimura Y, Horiike S, Taniwaki M, Kobayashi T, Kuroda J. Chromosomal abnormality variation
detected by G-banding is associated with prognosis of diffuse large B-cell lymphoma treated by RCHOP-based therapy. Cancer Med. 2018;7:655-664.
31. Kitagawa N, Ushigome E, Matsumoto S, Oyabu C, Ushigome H, Yokota I, Asano M, Tanaka M,
Yamazaki M, Fukui M. Threshold value of home pulse pressure predicting arterial stiffness in patientswith type 2 diabetes: KAMOGAWA-HBP study. J Clin Hypertens. 2018;20:472-477.
30. Shimoyama H, Isotani S, China T, Nagata M, Yokota I, Kitamura K, Wakumoto Y, Ide H, Muto S,
Tujimura A, Yamaguchi R, Horie S. Automated renal cortical volume measurement for assessment ofrenal function in patients undergoing radical nephrectomy. Clin Exp Nephrol. 2017;21:1124-1130.
29. Kan H, Arai Y, Kobayashi M, Nakagawa S, Inoue H, Hino M, Komaki S, Ikoma K, Ueshima K, Fujiwara
H, Yokota I, Kubo T. Fixed-flexion view X-ray of the knee superior in detection and follow-up of knee
osteoarthritis. Medicine. 2017; 96:e9126.
28. Oyabu C, Ushigome E, Matsumoto S, Tanaka T, Hasegawa G, Nakamura N, Ohnishi M, Tsunoda S,
Ushigome H, Yokota I, Tanaka M, Asano M, Yamazaki M, Fukui M. Maximum home blood pressure
is a useful indicator of diabetic nephropathy in patients with type 2 diabetes mellitus: KAMOGAWAHBP study. Diab Vasc Dis Res. 2017; 14: 477-484.
27. Taniguchi Y, Kitamura A, Murayama H, Amano H, Shinozaki T, Yokota I, Seino S, Nofuji Y, Nishi M,
Yokoyama Y, Matsuyama Y, Fujuwara Y, Shinkai S. Mini-mental state examination score trajectories
and incident disabling dementia among community-dwelling older Japanese. Geriatr Gerontol Int.
2017;17:1928-1935.
26. Kitazawa K, Kayukawa K, Wakimasu K, Yokota I, Inatomi T, Hieda O, Mori K, Sotozono C, Kinoshita
S. Predictive clinical factors of cystoid macular edema in patients with Descemet’s stripping automatedendothelial keratoplasty. Sci Rep. 2017; 7: 7412.
25. Kawamura T, Wada H, Sakiyama N, Ueda Y, Shirakawa A, Okada Y, Sanada K, Nakase K, Mandai K,
Suzuki A, Kamaguchi M, Morita A, Nishioji K, Tanaka K, Mochizuki N, Uno K, Yokota I, Kobayashi
M, Yasuda K. Examination time as a quality indicator of screening upper gastrointestinal endoscopy
for asymptomatic examinees. Dig Endosc. 2017;29:569-575.
24. Masuda N, Lee SJ, Ohtani S, Im YH, Lee ES, Yokota I, Kuroi K, Im SA, Park BW, Kim SB, Yanagita
Y, Ohno S, Takao S, Aogi K, Iwata H, Jeong J, Kim A, Park KH, Sasano H, Ohashi Y, Toi M. Adjuvant
capecitabine for breast cancer after preoperative chemotherapy. N Engl J Med. 2017;376:2147-2159.
23. Yamaue H, Shimizu A, Hagiwara Y, Sho M, Yanagimoto H, Nakamori S, Ueno H, Ishii H, Kitano M,
Sugimori K, Maguchi H, Ohkawa S, Imaoka H, Hashimoto D, Ueda K, Nebiki H, Nagakawa T, Isayama
H, Yokota I, Ohashi Y, Shirasaka T. Multicenter, randomized, open-label phase II study comparing
S-1 alternate-day oral therapy with the standard daily regimen as a first-line treatment in patientswith unresectable advanced pancreatic cancer. Cancer Chemother Pharmacol. 2017;79:813-823.
22. Kitazawa K, Kayukawa K, Wakimasu K, Yokota I, Inatomi T, Hieda O, Mori K, Sotozono C, Kinoshita
S. Cystoid macular edema after Descemet’s stripping automated endothelial keratoplasty. Ophthalmology. 2017;124:572-3.
21. Ushigome E, Matsumoto S, Oyabu C, Ushigome H, Yokota I, Hasegawa G, Nakamura N, Tanaka M,
Yamazaki M, Fukui M. Olmesartan with azelnidipine versus with trichlormethiazide on home bloodpressure variability in patients with type II diabetes mellitus. J Am Soc Hypertens. 2017: 11; 140-147.

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20. Nagao M, Yamamoto M, Matsumura Y, Yokota I, Takakura S, Teramukai S, Ichiyama S. Complete
adherence to evidence-based quality-of-care indicators for Staphylococcus aureus bacteremia resulted
in better prognosis. Infection. 2017; 45:83-91.
19. Kanezaki S, Nakamura S, Nakamura M, Yokota I, Matsushita T. Curtain osteophyte is one of therisk factors for poor outcome of rotational acetabular osteotomy. Int Orthop. 2017;41:265-70.
18. Taniguchi Y, Kitamura A, Seino S, Murayama H, Amano H, Nofuji Y, Nishi M, Yokoyama Y, Shinozaki T, Yokota I, Matsuyama Y, Fujiwara Y, Shinkai S. Gait performance trajectories and incident
disabling dementia among community-dwelling older Japanese. J Am Med Dir Assoc. 2017;18:192.e13192.e20.
17. Matsuda M, Oh-hashi K, Yokota I, Sawa T, Amaya F. Acquired exchange protein directly activated bycyclic adenosine monophosphate activity induced by p38MAPK in primary afferent neurons contributes
to sustaining postincisional nociception. Anesthesiology. 2017;126:150-162.
16. Sowa Y, Yokota I, Itsukage S, Nakatsukasa K, Sakaguchi K, Taguchi T, Numajiri T. Evaluationof the severity of capsular contracture using elastography after breast implant reconstruction. Clin
Hemorheol Microcirc. 2017;66:1-6.
15. Harada K, Ochi K, Taguchi T, Nakamura T, Kanazawa M, Yoshida N, Neriya H, Okagaki M, Nishida
N, Takishita Y, Yamamoto Y, Wada S, Kuwahata M, Yokota I, Sekido K, Higashi A. Validity of theshort nutritional assessment questionnaire for Japanese patients with cancer undergoing outpatientchemotherapy. J Med Invest. 2017;64:117-121.
14. Yanishi K, Nakamura T, Nakanishi N, Yokota I, Zen K, Yamano T, Shiraishi H, Shirayama T, Shiraishi
J, Sawada T, Kohno Y, Kitamura M, Furukawa K, Matoba S. A simple risk stratification model for STelevation myocardial infarction (STEMI) from the combination of blood examination variables: acute
myocardial infarction-Kyoto multi-center risk study group. PLoS One. 2016 Nov 11;11:e0166391.
13. Taniguchi Y, Fujiwara Y, Murayama H, Yokota I, Matsuo E, Seino S, Nofuji Y, Nishi M, Matsuyama Y, Shinkai S. Prospective study of trajectories of physical performance and mortality amongcommunity-dwelling older Japanese. J Gerontol A Biol Sci Med Sci. 2016; 71:1492-9.
12. Minamisawa A, Narumoto J, Yokota I, Fukui K. Evaluation of factors associated with psychiatricpatient dropout at a university outpatient clinic in Japan. Patient Prefer Adherence. 2016; 10: 190311.
11. Tatekawa S, Kohno A, Ozeki K, Watamoto K, Ueda N, Yamaguchi Y, Kobayashi T, Yokota I, Teramukai S, Taniwaki M, Kuroda J, Morishita Y. A novel diagnostic and prognostic biomarker panel
for endothelial cell damage-related complications in allogeneic transplantation. Biol Blood Marrow
Transplant. 2016; 22: 1573-81.
10. Kitazawa K, Yokota I, Sotozono C, Kinoshita S. Measurement of corneal endothelial surface area
using anterior segment optical coherence tomography in normal subjects. Cornea. 2016; 35: 1229-33.
9. Nakamura Y, Hieda O, Yamamura K, Wakimasu K, Yokota I, Kinoshita S. Comparative study ofseven-year outcomes following laser in situ keratomileusis with those of trans-epithelial photorefractive
keratectomy. Nihon Ganka Gakkai Zasshi. 2016; 120: 487-93.
8. Tsuji Y, Noto Y, Shiga K, Yokota I, Nakagawa M, Mizuno T. Does hand dominance affect peripheral
nerve excitability? Clin Neurophysiol. 2016; 127: 1921-2.
7. Kadoya A, Ogawa G, Kawakami S, Yokota I, Hatanaka Y, Uchibori A, Chiba A, Sonoo M. The
correlation between the change of distal motor latency of the median nerve and the abundant A-waves
in Guillain-Barre syndrome. J Neurol Neurosurg Psychiatry. 2016; 87: 444-6.

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6. Kobayashi T, Kuroda J, Yokota I, Tanba K, Fujino T, Kuwahara S, Isa R, Yamaguchi J, Kawata E,
Akaogi T, Uchiyama H, Kaneko H, Uoshima N, Kobayashi Y, Teramukai S, Taniwaki M. The Kyoto
Prognostic Index for patients with diffuse large B-cell lymphoma in the rituximab era. Blood Cancer
J. 2016; 6: e383;
5. Isotani S, Shimoyama H, Yokota I, Noma Y, Kitamura K, China T, Saito K, Hisasue SI, Ide H,
Muto S, Yamaguchi R, Ukimura O, Gill IS, Horie S. Novel prediction model of renal function after
nephrectomy from automated renal volumetry with preoperative multidetector computed tomography(MDCT). Clin Exp Nephrol. 2015; 19: 974-81.
4. Isotani S, Shimoyama H, Yokota I, China T, Hisasue SI, Ide H, Muto S, Yamaguchi R, Ukimura
O, Horie S. Feasibility and accuracy of computational robot-assisted partial nephrectomy planning byvirtual partial nephrectomy analysis. Int J Urol. 2015; 22:439-46.
3. Kitamura K, Muto S, Yokota I, Hoshimoto K, Kaminaga T, Noguchi T, Sugiura S, Ide H, Yamaguchi
R, Furui S, Horie S. Feasibility of multiparametric prostate magnetic resonance imaging in the detectionof cancer distribution: histopathological correlation with prostatectomy specimens. Prostate Int. 2014;
2:188-95.
2. Aihara T, Yokota I, Hozumi Y, Aogi K, Iwata H, Tamura M, Fukuuchi A, Makino H, Kim R, Andoh
M, Tsugawa K, Ohno S, Yamaguchi T, Ohashi Y, Watanabe T, Takatsuka Y, Mukai H. Anastrozole
versus tamoxifen as adjuvant therapy for Japanese postmenopausal patients with hormone-responsive
breast cancer: efficacy results of long-term follow-up data from the N-SAS BC 03 trial. Breast Cancer
Res Treat. 2014; 148: 337-43.
1. Katakami N, Kunikane H, Takeda K, Takayama K, Sawa T, Saito H, Harada M, Yokota S, Ando K,
Saito Y, Yokota I, Ohashi Y, Eguchi K. Prospective Study on the incidence of bone metastasis (BM)and skeletal-related events (SREs) in Patients (pts) with stage IIIB and IV lung cancer–CSP-HOR 13.
J Thorac Oncol. 2014; 9:231-8.

Reviews and Others
5. Yokota I, Okada K, Takagi R. Use of basket trial design in investigator initiated clinical trials formolecular-targeted agents. Jpn Pharmacol Ther 49: s12–15; 2021. (in Japanese)
4. Shinozaki T, Yokota I, Oba K, Kozuma K, Sakamaki K. Measures for evaluating risk prediction
models: a review. Japanese Journal of Biometrics 41:1–36; 2020. (in Japanese)
3. Yokota I. Single-arm design with time-to-event outcome. The Japanese Journal of Pediatric Hematology/Oncology 56:429–31; 2019. (in Japanese)
2. Yokota I. Reproducibility, Correlation coefficient and Bland-Altman plot. Coronary Intervention 13:
47–52; 2017. (in Japanese)
1. Yokota I, Teramukai S. Pitfalls in meta-analysis. Cardioangiology 79: 267–70; 2016. (in Japanese)

Presentations (Major’s only)
About biostatistical methodology
Okada K, Yokota I. Two one-sided test-then-pool method for clinical trials. 43rd Annual Conference of
the International Society of Clinical Biostatistics. Newcastle, UK Aug 24, 2022.
Inao T, Yokota I. Exact sequential design in a single-arm study with early termination for binary
outcome. 2022 Japan Biometrics Society, Tokyo, Japan, May 14, 2022.

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Yokota I. Impact of the effective sample size of survival rate by right censoring. 2022 Japan Biometrics
Society, Tokyo, Japan, May 13, 2022.
Inao T, Yokota I. Comparison of sequential test for binary outcome. Japanese Classification Society
2021 symposium, Okinawa, Japan, Dec 12, 2021.
Okura H, Inao T, Yokota I. Estimation of restricted mean survival time for interval-censored data using
midpoint imputation. Japanese Classification Society 2021 symposium, Okinawa, Japan, Dec 11, 2021.
Yokota I, Sakamaki K. Chance of a longer survival using pseudo-observations. Japanese Joint Statistical
Meeting 2021, Virtual, Sep 9, 2021.
Inao T, Okada K, Yang Y, Yokota I. Estimation of sensitivity and specificity in the absence of a gold
standard for data with rare positive frequencies. Japanese Classification Society 39th Annual meeting,
Kyoto, Japan, Nov 7, 2020.
Yokota I, Sakamaki K. Regression model for personalized chance of longer survival using pseudoobservations. 41st Annual Conference of the International Society of Clinical Biostatistics, Krakow,
Poland (Virtual), Aug 25, 2020.
Yokota I, Uemura Y. Using restricted mean survival time in a non-inferiority trial. The VIth International Society for Biopharmaceutical Statistics, Kyoto, Japan, Aug 28, 2019.
Yokota I. Landmarking model for dynamic prediction. The biometrics society of Japan seminar 2018,
Kyoto, Japan, Dec 7, 2018.
Yokota I. Single-arm clinical trial design with time-to-event outcome. Development and application of
statistical methods for clinical research and epidemiology, Shizuoka, Japan, May 11, 2018.
Yokota I. United milestones survival analysis in single-arm trial. 2nd Pacific Rim Cancer Biostatistics
Workshop, Kanazawa, Japan, August 13, 2017.
Yokota I, Teramukai S. United milestones survival analysis in single-arm trial. 38th Annual Conferenceof the International Society for Clinical Biostatistics, Vigo, Spain, July 11, 2017. Abstract T31.
Yokota I. Comparing the tests for a survival curve at a fixed time point in single arm study. ENAR
2017 Spring meeting, Washington DC, Canada, March 12-15, 2017. Posters 8j.
Yokota I, Kashiwabara K, Sakamaki K, Teramukai S. Comparison of sequential clinical trial designs with
time-to-event outcomes in small populations. XXVIIIth International Biometric Conference, Victoria,
BC, Canada, July 10-15, 2016. Abstract 2464724.
Yokota I, Matsuyama Y. Dynamic prediction for repeated events data based on landmark model using
dynamic pseudo observations. 36th Annual Conference of the International Society for Clinical Biostatistics, Utrecht, The Netherlands, August 23-27, 2015. Abstract P07-5.
Yokota I, Matsuyama Y. Evaluation of surrogate endpoint by dynamic prediction approach. 2015 annual
meeting of the biometric society of Japan, Kyoto, Japan, March 12, 2015.
Yokota I, Matsuyama Y, Ohashi Y. Extension on a landmarking model using a fractional polynomial
function for dynamic prediction. 34th Annual Conference of the International Society for Clinical Biostatistics, Munich, Germany, August 25-29, 2013. Abstract P136.
Yokota I, Matsuyama Y, Ohashi Y. Comparison of the tests for interval-censored data with differential
assessment times. XXVIth International Biometric Conference, Kobe, Japan, August 28, 2012. Abstract338.

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Yokota I, Matsuyama Y, Ohashi Y. Simulation studies on the analysis of interval-censored survival
data with differential assessment times. 2012 Joint Statistical Meetings, San Diego, CA, July 30, 2012.
Abstract 253.
Yokota I. Analysis of interval-censored survival data with differential assessment times. 6th Biostatistics
Network, Fukuoka, August 3, 2011.

About medical research
Yokota I. Visualizing statistical models via R-shiny. DIA Japan annual meeting 2021. Tokyo, Japan,
Oct 26, 2021.
Yokota I, Takagi R, Okada K. Use of basket study design in clinical trials with molecular targeted drugs.
The 12th annual meeting of Japan Society of Clinical Trials and Research, Tokyo, Japan (Virtual), Feb
12, 2021.
Yokota I. Single-arm design with time-to-event outcome. The 60th Annual Meeting of the JapaneseSociety of Pediatric Hematology/Oncology, Kyoto, Japan, Nov 16, 2018.
Yokota I. Survival analysis: to develop a prediction model. Hokkaido university hospital the clinicalresearch and medical innovation center, Sapporo, Japan, Jun 28, 2018.
Yokota I. Overview of statistical analysis in clinical research. The 33rd annual meeting of Japanesesociety for infection prevention and control, Tokyo, Japan, Feb 24, 2018.
Yokota I. Statistical method for interim analysis/monitoring. 5th biostatistics seminar in TOKYO (byARO Council), Tokyo, Japan, Feb 3, 2018.
Yokota I. Statistical method for observational study -Beyond P-value-. Japanese red cross Kyoto daiichi
hospital, Kyoto, Japan, Jan 18, 2018.
Yokota I. Statistical method for interim analysis/monitoring. 5th annual meeting of ARO Council,
Nagoya, Japan, Sep 25, 2017.

Last updated: January 5, 2023