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Paraformaldehyde,JUNSEI CHEMICAL CO., LTD.,58295jis_J_E1-2,25/Dec/2023
Date of issue for the 1st edition : 16/Jun/2015
Date of revision : 25/Dec/2023

Safety Data Sheet

Section 1. Identification of the substance/mixture and of the company/undertaking
Product identifier:Product name: Paraformaldehyde
Reference number(SDS):58295jis_J_E1-2
Product type：
Reagent
Details of the supplier of the safety data sheet
Manufacturer/Supplier: JUNSEI CHEMICAL CO., LTD.
Address: 1-6, Ohmano-cho, Koshigaya-shi, Saitama 343-0844, Japan
Division: Quality Assurance Department
Telephone number: +81-48-986-6161
FAX: +81-48-989-2787
e-mail address: shiyaku-t@junsei.co.jp

Section 2. Hazards identification
GHS classification and label elements of the product
Classification of the substance or mixture
PHYSICAL AND CHEMICAL HAZARDS
Flammable solids: Category 2
HEALTH HAZARDS
Acute toxicity (Oral): Category 4
Acute toxicity (Inhalation): Category 4
Skin corrosion/irritation: Category 2
Serious eye damage/eye irritation: Category 2ASpecific target organ toxicity - single exposure: Category 1 (respiratory organs)
ENVIRONMENT HAZARDS
Hazardous to the aquatic environment, short-term (acute): Category 3
Hazardous to the aquatic environment, long-term (chronic): Category 3(Note) GHS classification without description: Not classified/Classification not possible
Label elements

Signal word: Danger
HAZARD STATEMENT
H228-Flammable solid
H302-Harmful if swallowed
H332-Harmful if inhaled
H315-Causes skin irritation
H319-Causes serious eye irritation
H370-Causes damage to organs
H402-Harmful to aquatic life
H412-Harmful to aquatic life with long lasting effects
PRECAUTIONARY STATEMENT
Prevention
Avoid release to the environment.
Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking.

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Paraformaldehyde,JUNSEI CHEMICAL CO., LTD.,58295jis_J_E1-2,25/Dec/2023
Ground and bond container and receiving equipment.
Use explosion-proof electrical/ventilating/lighting equipment.
Do not breathe dust/mist.
Use only outdoors or in a well-ventilated area.
Wash contaminated parts thoroughly after handling.
Wear protective gloves/protective clothing/eye protection/face protection.
Do not eat, drink or smoke when using this product.
Response
In case of fire: Use water mist, alcohol-resistant foam, dry powder, CO2 to extinguish.
Call a POISON CENTER/doctor/physician if you feel unwell.
IF exposed or concerned: Call a POISON CENTER/doctor/physician.
IF INHALED: Remove person to fresh air and keep comfortable for breathing.
IF ON SKIN: Wash with plenty of soap and water.
If skin irritation occurs: Get medical advice/attention.
Take off contaminated clothing and wash it before reuse.
IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, ifpresent and easy to do. Continue rinsing.
If eye irritation persists: Get medical advice/attention.
IF SWALLOWED: Rinse mouth. Call a POISON CENTER/doctor/physician if you feel unwell.
Storage
Store locked up.
Disposal
Dispose of contents/container in accordance with local/national regulation.
Specific Physical and Chemical hazards
Flammable solid. Vapor/air mixture may explode.

Section 3. Composition/information on ingredients
Mixture/Substance selection:
Substance
Ingredient name:Paraformaldehyde
Content (%):95 <Chemical formula:HO(CH2O)nH n=8～100
Chemicals No, Japan:9-1941
CAS No.:30525-89-4
Note : The figures shown above are not the specifications of the product.

Section 4. First-aid measures
Descriptions of first-aid measures
General measures
Call a POISON CENTER/doctor/physician if you feel unwell.
Keep victim warm and quiet.
Call emergency medical service.
IF INHALED
Remove person to fresh air and keep comfortable for breathing.
Give artificial respiration if victim is not breathing.
Administer oxygen if breathing is difficult.
Call a POISON CENTER/doctor/physician if you feel unwell.
IF ON SKIN (or hair）
Take off immediately all contaminated clothing. Rinse skin with water or shower.
Wash with plenty of soap and water.
If skin irritation or rash occurs: Get medical advice/attention.
If skin irritation occurs: Get medical advice/attention.

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Paraformaldehyde,JUNSEI CHEMICAL CO., LTD.,58295jis_J_E1-2,25/Dec/2023
Removal of solidified molten material from skin requires medical assistance.
Remove and isolate contaminated clothing and shoes.
IF IN EYES
Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy
to do. Continue rinsing.
If eye irritation persists: Get medical advice/attention.
IF SWALLOWED
Rinse mouth. Do NOT induce vomiting.
If victim is conscious, give 1 - 2 glasses of water.
Call a POISON CENTER/doctor/physician if you feel unwell.
Most important symptoms and effects, both acute and delayed(Symptoms when inhalation or ingestion)
Cough. Sore throat. Burning sensation. Laboured breathing.
(Symptoms when skin and/or eye contact)
Conjunctival redness of the eyes. Redness of the skin. Pain. Burns of the eyes.
Indication of any immediate medical attention and special treatment needed
Ensure that medical personnel are aware of the material(s) involved, and take precautions
to protect themselves.

Section 5. Fire-fighting measures
Extinguishing media
Suitable extinguishing media
In case of fire, use water mist, alcohol-resistant foam, dry powder, CO2 to extinguish.
Unsuitable extinguishing media
Unsuitable extinguishing media data is not available.
Specific hazards arising from the substance or mixture
Containers may explode when heated.
Fire may produce irritating, corrosive and/or toxic gases.
Runoff from fire control or dilution water may cause pollution.
Advice for firefighters
Specific fire-fighting measures
Evacuate non-essential personnel to safe area.
Special protective equipment and precautions for fire-fighters
Wear fire resistant or flame retardant clothing.
Wear protective gloves/protective clothing/eye protection/face protection.
Firefighters should wear self-contained breathing apparatus with a full facepiece operated
in the positive pressure mode.

Section 6. Accidental release measures
Personnel precautions, protective equipment and emergency procedures
Keep unauthorized personnel away.
In case of contact with substance, immediately flush skin or eyes with running water for atleast 20 minutes.
Ventilate area until material pick up is complete.
Wear proper protective equipment.
Do not touch or walk through spilled material.
Environmental precautions
Avoid release to headsprings, rivers, lakes, ocean and groundwater.
Methods and materials for containment and cleaning up
Sweep up, place in a bag and hold for waste disposal.
If appropriate, moisten first to prevent dusting.

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Paraformaldehyde,JUNSEI CHEMICAL CO., LTD.,58295jis_J_E1-2,25/Dec/2023
Preventive measures for secondary accident
Collect spillage.
ELIMINATE all ignition sources (no smoking, flares, sparks or flames in immediate area).
Keep out of low areas.

Section 7. Handling and storage
Precautions for safe handling
Preventive measures(Exposure Control for handling personnel)
Do not breathe dust/mist.
(Protective measures against fire and explosion)
Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking.
Ground and bond container and receiving equipment.
Use explosion-proof electrical/ventilating/lighting equipment.
(Exhaust/ventilator)
Exhaust/ventilator should be available.
(Safety treatments)
Avoid contact with skin.
Avoid contact with eyes.
Safety Measures
Use only outdoors or in a well-ventilated area.
Wear protective gloves/protective clothing/eye protection/face protection.
Use personal protective equipment as required.
When using do not eat, drink or smoke.
Any incompatibilities
Acids, Bases, Oxidizing agents should not be mixed with the chemicals.
Advice on general occupational hygiene
Wash contaminated parts thoroughly after handling.
Do not eat, drink or smoke when using this product.
Take off contaminated clothing and wash it before reuse.
Storage
Conditions for safe storage
Store in a well-ventilated place.
Keep container tightly closed.
Keep cool. Protect from sunlight.
Store in accordance with local/national regulation.
Store locked up.
Container and packaging materials for safe handling data is not available.
Specific end use(s)See information in Section 7.1 and 7.2 for handling and storage recommendations. See
Section 8 for exposure controls and personal protection recommendations.

Section 8. Exposure controls/personal protection
Control parameters
Control value and concentration standard value are not available in ISHA.
Adopted value
Adopted value in JSOH is not available.
Adopted value in ACGIH is not available.
Exposure controls
Appropriate engineering controls
Do not use in areas without adequate ventilation.
Eye wash station should be available.

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Paraformaldehyde,JUNSEI CHEMICAL CO., LTD.,58295jis_J_E1-2,25/Dec/2023
Washing facilities should be available.
Individual protection measures
Respiratory protection
Wear respiratory protection.
Recommended respiratory protection：Dust mask(e.g. JIS T8151)
Hand protection
Wear protective gloves. Recommended material(s): nitrile
Inspect before use and replace worn or damaged gloves.
Contact the glove manufacturer for specific advice on glove selection and breakthroughtimes for your use conditions.
Chemical-resistant, impervious gloves complying with an approved standard (e.g. JIS T8116)
should be used.
Eye protection
Wear chemical safety goggle.
Wear eye/face protection.
Skin and body protection
Wear impervious clothing and boots in case of repeated or prolonged treatment.
Personal protective equipment for the body and skin should be selected based on the task
being performed and the risks involved.

Section 9. Physical and Chemical Properties
Information on basic physical and chemical properties
Physical state: Solid～Powder
Color: White
Odor: Irritant odor
Odor threshold data is not available.
Melting point/Freezing point: 120～180℃
Boiling point or initial boiling point data is not available.
Boiling range data is not available.
Flammability (gases, liquids and solids) data is not available.
Lower and upper explosion limit/flammability limit:
Lower explosion limit: 7.0 vol %Upper explosion limit: 73.0 vol %Flash point: (c.c.)71℃
Auto-ignition temperature: 300℃
Decomposition temperature: 120～180℃
Self-Accelerating Decomposition Temperature/SADT data is not available.
pH data is not available.
Dynamic viscosity data is not available.
Kinematic viscosity data is not available.
Solubility:
Solubility in water: 200 g/L (18℃)
Solubility in solvent: Insoluble in alcohol, ether.
n-Octanol/water partition coefficient data is not available.
Vapor pressure: ＜0.16 kPa （25℃）
Density and/or relative density: 1.46(15℃)
Relative vapor density (Air=1): 1.03
Relative density of the Vapor/air - mixture at 20℃ (Air = 1) data is not available.
Particle characteristics data is not available.
Other information
Critical temperature data is not available.
Evaporation rate data is not available.
VOC data is not available.

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Paraformaldehyde,JUNSEI CHEMICAL CO., LTD.,58295jis_J_E1-2,25/Dec/2023
Section 10. Stability and Reactivity
Reactivity
Reactivity data is not available.
Chemical stability
Stable under normal storage/handling conditions.
Possibility of hazardous reactions
May form explosive dust-air mixtures.
If dry, it can be charged electrostatically by swirling, pneumatic transport, pouring, etc.
Decomposes on heating and on contact with acids, bases and oxidants. This produces
flammable formaldehyde.
Conditions to avoid
Contact with incompatible materials.
Open flames. Heating.
Incompatible materials
Acids, Bases, Oxidizing agents
Hazardous decomposition products
Carbon oxides, Formaldehyde

Section 11. Toxicological Information
Information on toxicological effects
Acute toxicity
Acute toxicity (Oral)[Product]Category 4, Harmful if swallowed[Data for components of the product][GHS Cat. Japan, base data]
rat LD50=800mg/kg (Canada CMP, 2019)
Acute toxicity (Dermal)[Product]
Based on available data, the classification criteria are not met.
[Data for components of the product][GHS Cat. Japan, base data]
rabbit LD50=10000mg/kg (Canada CMP, 2019)
Acute toxicity (Inhalation)[Product]Category 4, Harmful if inhaled[Data for components of the product][GHS Cat. Japan, base data]
dust: rat LC50=1.07mg/L/4hr (Canada CMP, 2019)
Irritant properties
Skin corrosion/irritation[Product]Category 2, Causes skin irritation[Data for components of the product][GHS Cat. Japan, base data]skin irritant（Canada CMP, 2019）
Serious eye damage/irritation[Product]Category 2A, Causes serious eye irritation[Data for components of the product][GHS Cat. Japan, base data]eye irritant（Canada CMP, 2019）7/10
Paraformaldehyde,JUNSEI CHEMICAL CO., LTD.,58295jis_J_E1-2,25/Dec/2023
Sensitization
Respiratory sensitization[Product]Classification not possible (Insufficient data available or no data available).
[Data for components of the product]
No data available.
Skin sensitization[Product]Classification not possible (Insufficient data available or no data available).
[Data for components of the product]
No data available.
Germ cell mutagenicity[Product]Classification not possible (Insufficient data available or no data available).
[Data for components of the product]
No data available.
Carcinogenicity[Product]Classification not possible (Insufficient data available or no data available).
[Data for components of the product]
No data available.
Reproductive toxicity[Product]Classification not possible (Insufficient data available or no data available).
[Data for components of the product]
No data available.
Specific target organ toxicity (STOT)
STOT-single exposure[Product]Category 1, Causes damage to organs[Data for components of the product][cat.1][GHS Cat. Japan, base data]
respiratory system (AICIS IMAP, 2019)
STOT-repeated exposure[Product]Classification not possible (Insufficient data available or no data available).
[Data for components of the product]
No data available.
Aspiration hazard[Product]Classification not possible (Insufficient data available or no data available).
[Data for components of the product]
No data available.

Section 12. Ecological Information
Toxicity
Aquatic toxicity[Product]Category 3, Harmful to aquatic life
Category 3, Harmful to aquatic life with long lasting effects

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Paraformaldehyde,JUNSEI CHEMICAL CO., LTD.,58295jis_J_E1-2,25/Dec/2023[Data for components of the product]
Hazardous to the aquatic environment, short-term (acute)[GHS Cat. Japan, base data]
Fish (bluegill) LC50=39.1mg/L/96hr (EPA AQUIRE 2018 et al.)
Water solubility[Data for components of the product]
200 g/L (18℃) (HSDB)
Persistence and degradability
Persistence and degradability data is not available.
Bioaccumulative potential
Bioaccumulative potential data is not available.
Mobility in soil
Mobility in soil data is not available.
Other adverse effects
Ozone depleting chemical data is not available.

Section 13. Disposal considerations
Description of waste residues and information on their safe handling and methods of disposal,
including the disposal of any contaminated packaging
Waste treatment methods
Avoid release to the environment.
Dispose of contents/container in accordance with local/national regulation.

Section 14. Transport Information
UN No., UN CLASS
UN Number or ID Number : 2213
UN Proper Shipping Name : PARAFORMALDEHYDEClass or division (Transport hazard class) : 4.1
Packing group : III
ERG GUIDE No.: 133
IMDG Code (International Maritime Dangerous Goods Regulations)
UN Number or ID Number : 2213
UN Proper Shipping Name : PARAFORMALDEHYDEClass or division (Transport hazard class) : 4.1
Packing group : III
IATA (Dangerous Goods Regulations)
UN Number or ID Number : 2213
UN Proper Shipping Name : PARAFORMALDEHYDEClass or division (Transport hazard class) : 4.1
Hazard labels : Flamm.solid
Packing group : III
Environmental hazards
Marine pollutants (yes/no) : noTransport in bulk according to Annex II of MARPOL 73/78 and the IBC CodeNot applicable to Transport in bulk according to Annex II of MARPOL and the IBC CodeSection 15. Regulatory Information
Safety, health and environmental regulations/legislation specific for the substance or mixture
Mutagen [MHLW_J Notice]
Paraformaldehyde

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Paraformaldehyde,JUNSEI CHEMICAL CO., LTD.,58295jis_J_E1-2,25/Dec/2023
U.S. Toxic Substances Control Act (TSCA) Inventory
Chemicals listed in TSCA Inventory
30525-89-4
All components are listed or exempted.
Other regulatory information
We are not able to check up the regulatory information with regard to the substances inyour country or region, therefore, we request this matter would be filled by yourresponsibility.
Regulatory information with regard to this substance in your country or in your region
should be examined by your own responsibility.
Ensure this material in compliance with federal requirements and ensure conformity to local
regulations.
Regulatory information in this section are limited to intentional ingredient(s), but does
not contain information on non-intentional ingredients or impurities which are not informedby supplier(s).
Chemical safety assessment
Advice on safe handling for this product can be found in sections 7 and 8 of this SDS.

Section 16. Other information
GHS classification and labellingH228-Flammable solids, Category 2: H228 Flammable solid
H302-Acute toxicity, Category 4: H302 Harmful if swallowed
H332-Acute toxicity, Category 4: H332 Harmful if inhaled
H315-Skin corrosion/irritation, Category 2: H315 Causes skin irritation
H319-Serious eye damage/eye irritation, Category 2A: H319 Causes serious eye irritation
H370-STOT - single exposure, Category 1: H370 Causes damage to organs
H402-Hazardous to the aquatic environment, short-term (acute), Category 3: H402 Harmful to aquatic life
H412-Hazardous to the aquatic environment, long-term (chronic), Category 3: H412 Harmful toaquatic life with long lasting effects
References and sources for data
Globally Harmonized System of classification and labelling of chemicals, UN
Recommendations on the TRANSPORT OF DANGEROUS GOODS 22nd edit., 2021 UN
IMDG Code, 2020 Edition (Incorporating Amendment 40-20)
IATA Dangerous Goods Regulations (64th Edition) 2023
2020 EMERGENCY RESPONSE GUIDEBOOK (US DOT)
2023 TLVs and BEIs. (ACGIH)
JIS Z 7252 : 2019
JIS Z 7253 : 20192022 Recommendation on TLVs (JSOH)
Notification No. 0111-1 (January 11, 2022), Chemical Hazards Control Division, Industrial
Safety and Health Department, Labour Standards Bureau, MHLW in Japan
Supplier's data/information
Chemicals safety data management system "GHS Assistant" Version 4.26 (https://www.asahi-ghs.com/)
NITE Chemical Risk Information Platform "NITE-CHRIP"(https://www.nite.go.jp/en/chem/chrip/chrip_search/systemTop)
GHS Classification Guidance for Enterprises 2019 Revised Edition (Ver. 2.0) （Mar. 2020, METI)
Abbreviations and acronyms
SDS (Safety Data Sheet)
LD50 (Lethal Dose, 50％)
LC50 (Lethal Concentration, 50％)
IARC (International Agency for Research on Cancer)
ACGIH (American Conference of Governmental Industrial Hygienists)
EPA (US Environmental Protection Agency)

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NTP (US National Toxicology Program)
JSOH (Japan Society for Occupational Health)EU (European Union)
EC50 (Effective Concentration, 50％)
NOEC (No Observed Effect Concentration)
BOD (Biochemical Oxygen Demand)
COD (Chemical Oxygen Demand)
BCF (Bioconcentration Factor)anh (anhydride)
General Disclaimer
This data sheet was created based on the information we currently have and may be revised
according to new information. In addition, the precautions apply only to normal handling,
and in the case of special handling, please make adequate countermeasure to maintain yoursafety.
The data given here is based on current knowledge and experience. The purpose of this
Safety Data Sheet is to describe the products in terms of their safety requirements. The
data does not signify any warranty with regard to the products' properties.
The GHS classification data given here is based on current Japan official data (NITE
published in 2022).