05/21/14

Order No.
Ref No.

Sequence - HPLC purification

825546596581811

100 nmole DNA Oligo, 50 Bases

5- TTT CGA GTG ATG GTT GTG CCT GCA CGA GAT TCA CAT TCA CGT CTC GGG AA -3

Properties

Amount of Oligo

Tm (50 nM naCl): 70.2 °C
GC Content: 50%
Molecular Weight: 15423
nmoles/OD260: 2.1

1.3
OD 260=ug/OD260: 32.5
Ext. Coefficient: 474400 L/(mole·cm)

Oligo Base Types
DNA Bases

Quantity

502.7
nMolesShipped To=0.04
mg

MBL ADMIN
MEDICAL AND BIOLOGICALLABORATORIES CO., LTD.
MBL DELIVERY CENTER, NIPPONEXPRESSNAGOYA-SHI, AICHI 457-0067
JAPAN(815) 261-9357
Customer No. 4407194 PO No. 22637

Modifications and Services
HPLC Purification
Mfg. ID 171266055•

Lyophilized contents may appear as either a translucent film or awhite powder. This variance does not affect the quality of the oligo.

•Please centrifuge tubes prior to opening. Some of the product may
have been dislodged during shipping.

Quantity1I.

Use Restrictions: Oligonucleotides and nucleic acid products are manufactured and sold by IDT for thecustomer's research purposes only. Resale of IDT products requires the express written consent of IDT.
Unless pursuant to a separate signed agreement by authorized IDT officials, IDT products are not soldfor (and have not been approved) for use in any clinical, diagnostic or therapeutic applications.
Obtaining license or approval to use IDT products in proprietary applications or in any non-research(clinical) applications is the customer's exclusive responsibility. IDT will not be responsible or liable forany losses, costs, expenses, or other forms of liability arising out of the unauthorized or unlicensed useof IDT products. Purchasers of IDT products shall indemnify and hold IDT harmless for any and alldamages and/or liability, however characterized, related to the unauthorized or unlicensed use of IDT
products. Under no circumstances shall IDT be liable for any consequential damages, resulting fromany use (approved or otherwise) of IDT products. All orders received by IDT, and all sales of IDT
products are made subject to the aforementioned use restrictions and customer indemnification of IDT.

II.

General Warranty: IDT's products are guaranteed to meet or exceed our published specifications for
identity, purity and yield as measured under normal laboratory conditions. If our product fails to meetsuch specifications, IDT will promptly replace the product. All other warranties are hereby expressly
disclaimed, including but not limited to, the implied warranties of merchantability and fitness for aparticular purpose, and any warranty that the products, or the use of products, manufactured by IDT will
not infringe the patents of one or more third-partiesAll orders received by IDT, and all sales of IDT
products are made subject to the aforementioned disclaimers of warranties.

III.

See http://www.idtdna.com/Catalog/Usage/Page1.aspx for further detailsa) Cy Dyes: The purchase of this Product includes a limited non-exclusive sublicense under U.S
Patent Nos. 5 556 959 and 5 808 044 and foreign equivalent patents and other foreign and U.S
counterpart applications to use the amidites in the Product to perform research. NO OTHER
LICENSE IS GRANTED EXPRESSLY, IMPLIEDLY OR BY ESTOPPEL. Use of the Product forcommercial purposes is strictly prohibited without written permission from Amersham Biosciences
Corp. For information concerning availability of additional licenses to practice the patented
methodologies, please contact Amersham Biosciences Corp, Business Licensing Manager,
Amersham Place, Little Chalfont, Bucks, HP79NA.
b)

BHQ: Black Hole Quencher, BHQ-0, BHQ-1, BHQ-2 and BHQ-3 are registered trademarks ofBiosearch Technologies, Inc., Novato, California, U.S.A Patents are currently pending for the BHQ
technology and such BHQ technology is licensed by the manufacturer pursuant to an agreementwith BTI and these products are sold exclusively for research and development use only. They
may not be used for human veterinary in vitro or clinical diagnostic purposes and they may not be
re-sold, distributed or re-packaged. For information on licensing programs to permit use for humanor veterinary in vitro or clinical diagnostic purposes, please contact Biosearch atlicensing@biosearchtech.com.

c)

MPI dyes: MPI dyes. This product is provided under license from Molecular Probes, Inc., forresearch use only, and is covered by pending and issued patents.

d)Molecular Beacons: Molecular Beacons. This product is sold under license from the Public HealthResearch Institute only for use in the purchaser’s research and development activities.

e)ddRNAi: This product is sold solely for use for research purposes in fields other than plants. Thisproduct is not transferable. If the purchaser is not willing to accept the conditions of this label
license, supplier is willing to accept the return of the unopened product and provide the purchaser
with a full refund. However if the product is opened, then the purchaser agrees to be bound by theconditions of this limited use statement. This product is sold by supplier under license from
Benitec Australia Ltd and CSIRO as co-owners of U.S Patent No. 6,573,099 and foreigncounterparts. For information regarding licenses to these patents for use of ddRNAi as atherapeutic agent or as a method to treat/prevent human disease, please contact Benitec atlicensing@benitec.com. For the use of ddRNAi in other fields, please contact CSIRO at
www.pi.csiro.au/RNAi.

f)

Dicer Substrate RNAi:•These products are not for use in humans or non-human animals and may not be used forhuman or veterinary diagnostic, prophylactic or therapeutic purposes. Sold under license ofpatents pending jointly assigned to IDT and the City of Hope Medical Center.
•This product is licensed under European Patents 1144623, 121945 and foreign equivalentsfrom Alnylam Pharmaceuticals, Inc., Cambridge, USA and is provided only for use inacademic and commercial research whose purpose is to elucidate gene function, including
research to validate potential gene products and pathways for drug discovery anddevelopment and to screen non-siRNA based compounds (but excluding the evaluation orcharacterization of this product as the potential basis for a siRNA based drug) and not for
any other commercial purposes. Information about licenses for commercial use (includingdiscovery and development of siRNA-based drugs) is available from Alnylam
Pharmaceuticals, Inc., 300 Third Street, Cambridge MA 02142, USA•
License under U.S. Patent # 6506559; Domestic and Foreign Progeny; including European
Patent Application # 98964202g)

LNAs: Protected by US. Pat No. 6,268,490 and foreign applications and patents owned orcontrolled by Exiqon A/S. For Research Use Only. Not for resale or for therapeutic use or use inhumansh)

Other siRNA duplexes: This product is provided under license from Molecular Probes, Inc., forresearch use only, and is covered by pending and issued patents.

i)

Acrydite: IDT is licensed under U.S Patent Number 6,180,770 and 5,932,711 to sell this productfor use solely in the purchaser’s own life sciences research and development activities. Resale, or
use of this product in clinical or diagnostic applications, or other commercial applications, requires
separate license from Mosaic, Inc.

j)

Iso-Bases: Licensed under EraGen, Inc. United States Patents Number 5,432,272; 6,001,983;6,037,120; and 6,140,496. For research use Only.

k)

Dig: Licensed from Roche Diagnostics GmbHl)

5' Nuclease Assay: The 5' Nuclease Assay and other homogenous amplification methods used inconnection with the Polymerase Chain Reaction (PCR) process are covered by patents owned byRoche Molecular Systems, Inc. and F. Hoffman La-Roche Ltd (Roche). No license to use the 5'
Nuclease Assay or any Roche patented homogenous amplification process is conveyed expressly
or by implication to the purchaser by the purchase of the above listed products or any other IDTproducts.

m)

Iowa Black® FQ and RQ: Iowa Black is a registered trademark of IDT, and Iowa Black-labeledoligos are covered by pending patents owned and controlled by IDT.

n)

IRDye® 700 and IRDye® 800: IRDye® 700 and IRDye® 800 are products manufactured underlicense from LI-COR® Biosciences, which expressly excludes the right to use this product inqPCR or AFLP applications.