https://dfns.u-shizuoka-ken.ac.jp/graduate/laboratory/112.html

Curriculum Vitae

Yuko Shimamura, Ph.D.
Position:

Assistant Professor

Laboratory: Laboratory of Food Hygiene
University:

School of Food and Nutritional Sciences, University of Shizuoka, 52-1 Yada,
Suruga-ku, Shizuoka, 422-8526, Japan
Tel: +81-54-264-5526
Fax: +81-54-264-5528
E-mail: shimamura@u-shizuoka-ken.ac.jp

Website:https://dfns.u-shizuoka-ken.ac.jp/labs/foodhygn/
https://dfns.u-shizuoka-ken.ac.jp/graduate/laboratory/112.html

Education
Ph.D. 2007,

Ochanomizu University, Tokyo, Japan
Human Environmental Science, Humanities and Science

M.S. 2004,

Ochanomizu University, Tokyo, Japan
Department of Lifescience, Humanities and Science

B.A. 2002,

Gakushuin Women's College, Tokyo, Japan
Faculty of International Cultural Communications

Experience
2011-PresentAssistant Professor, School of Food and Nutritional
Sciences, University of Shizuoka, Shizuoka, Japan

2008-2011

Postdoctoral Fellow, Institute of Environmental Science for Human Life,
Ochanomizu University, Tokyo, Japan

2007-2008

Postdoctoral Fellow, Graduate School of Humanities and Sciences,
Ochanomizu University, Tokyo, Japan

Publication◆ Papers (2019- Present)
1) Shimamura Y, Miyazaki M, Sawaki S, Inagaki R, Honda H, and Masuda S.: Formation ofglycidol fatty acid esters and 3-monochloro-1,2-propanediol fatty acid esters in heated foods.
J. Food Meas. Charact. 1-12 (2024).
2) Shimamura Y, Oura Y, Tsuchiya M, Yamanashi Y, Ogasawara A, Oishi M, Komuro M,
Sasaki K, and Masuda S.: Slightly acidic electrolyzed water inhibits inflammation induced bymembrane vesicles of Staphylococcus aureus. Front. Microbiol. 14: 1328055 (2023).
3) Shimamura Y, Wada Y, Tashiro M, Honda H, and Masuda S.: A comparison of the exposuresystem of glycidol‐related chemicals on the formation of glycidol‐hemoglobin adducts.
Food Sci. Nutr. (2023) First published: 30 October 2023
4) Shimamura Y, Noaki R, Oura Y, Ichikawa K, Kan T, and Masuda S.: Regulation ofstaphylococcal enterotoxin-induced inflammation in spleen cells from diabetic mice bypolyphenols. Microorganisms, 11(4): 1039 (2023).
5) Shimamura Y, Inagaki R, Oike M, Wada Y, Honda H, and Masuda S.: Potential role oflipase activity on the internal exposure assessment of glycidol released from its fatty acid
esters. Toxics, 11(2): 175 (2023).
6) Shimamura Y, Yui T, Horiike H, and Masuda S.: Toxicity of combined exposure toacrylamide and Staphylococcus aureus. Toxicol. Rep., 9: 876–882 (2022).
7) Mukaide K, Shimamura Y, Masuda S, Vongsak B, and Kumazawa S.: Antibacterial andantibiofilm activities of Thailand propolis against Escherichia coli. Nat. Prod. Commun.,
17(4): 1–5 (2022).
8) Noda K, Ando H, Tada K, Satake M, Nakauchi F, Tsutsuura S, Shimamura Y, Masuda S,and Murata M.: Acrylamide formation during pan-frying of mung bean sprouts. Food Sci.
Technol. Res., 28(4): 307–315 (2022).
9) Yamanashi Y, Shimamura Y#, Sasahara H, Komuro M, Sasaki K, Morimitsu Y, and Masuda
S.: Effects of growth stage on the characterization of enterotoxin A-producing
Staphylococcus aureus-derived membrane vesicles. Microorganisms, 10(3): 574 (2022).
#equal contribution10) Kitayama S, Igoshi A, Shimamura Y, Noda K, and Murata M.: Formation scheme and someproperties of a thiamine-derived pigment, pyrizepine, formed through the Maillard reaction.
Biosci. Biotechnol. Biochem., 86(5): 672–680 (2022).
11) Shimamura Y, Okuda A, Ichikawa K, Inagaki R, Ito S, Honda H, and Masuda S.: Factors
influencing the formation of chemical–hemoglobin adducts, Toxics, 10(1): 2 (2022).
12) Shimamura Y, Inagaki R, Oike M, Dong B, Gong W, and Masuda S.: Glycidol fatty acid
ester and 3-monochloropropane-1,2-diol fatty acid ester in commercially prepared foods.
Foods, 10(12): 2905 (2021).
13) Shimamura Y, Noaki R, Kurokawa A, Utsumi M, Hirai C, Kan T, and Masuda S.: Effect of(−)-epigallocatechin gallate on activation of JAK/STAT signaling pathway by staphylococcal
enterotoxin A. Toxins, 13(9): 609 (2021).
14) Kobayashi T, Toyoda T, Tajima Y, Kishimoto S, Tsunematsu Y, Sato M, Matsushita K,Yamada T, Shimamura Y, Masuda S, Ochiai M, Ogawa K, Watanabe K, Takamura-Enya T,Totsuka Y, Wakabayashi K, and Miyoshi N.: o-Anisidine dimer, 2-methoxy-N4-(2-methoxyphenyl) benzene-1,4-diamine, in rat urine associated with urinary bladdercarcinogenesis. Chem. Res. Toxicol., 34(3): 912-919 (2021).
15) Shimamura Y, Sei S, Nomura S, and Masuda S.: Protective effects of dried mature Citrus
unshiu peel (Chenpi) and hesperidin on aspirin-induced oxidative damage. J. Clin. Biochem.
Nutr., 68(2): 149-155 (2021).
16) Shimamura Y, Inagaki R, Honda H, and Masuda S.: Does external exposure of glycidolrelated

chemicals

influence

theformingof

thehemoglobin

adduct,N-(2,3-dihydroxypropyl)valine, as a biomarker of internal exposure to Glycidol? Toxics, 8: 119(2020)．
17) Shimamura Y, Shibata M, Sato M, Nagai R, Yang P, Shiokawa K, Kikuchi H, and Masuda
S.: Anti-hyperglycemic activity and inhibition of advanced glycation end products byLonicera japonica Thunb. in streptozotocin-induced diabetic rats. Food Sci. Technol. Res.,
26(6): 825-835 (2020).
18) Noda K, Amano Y, Shimamura Y, and Murata M.: Distribution of pyrrolothiazolate, apigment formed through the Maillard reaction between cysteine and glucose, in foods andbeverages and some of its properties. Food Sci. Technol. Res., 26(6): 735-742 (2020).
19) Shimamura Y, Shinke M, Hiraishi M, Tsuchiya Y, Egawa M, Ohashi N, and Masuda S.:
Influence of muscle fiber direction on migration of Salmonella Enteritidis, Staphylococcus
aureus, and Escherichia coli into raw chicken breast. J. Food Prot., 83(6): 928-934 (2020).
20) Shimamura Y, Utsumi M, Hirai C, Kurokawa A, Kan T, Ohashi N, and Masuda S.: Effect of(−)-epigallocatechin gallate to staphylococcal enterotoxin A on toxin activity. Molecules,25(8): 1867 (2020).
21) Matsuzaki K, Iwai K, Yoshikawa Y, Shimamura Y, Miyoshi N, Hiramoto S, Asada, K,Fukutomi R, Su, H, and Ohashi N.: Wheat bran intake enhances the secretion of bacteriabinding IgA in a lumen of the intestinal tract by incrementing short chain fatty acidproduction through modulation of gut microbiota. Nat. Prod. Commun., 15(4): 1-11 (2020).
22) Inagaki R, Uchino K, Shimamura Y, and Masuda S.: Investigation of DNA damage ofglycidol and glycidol fatty acid esters using Fpg-modified comet assay. Fundam. Toxicol.
Sci., 6(1): 9-14 (2019).
23) Inagaki R, Ito F, Shimamura Y, and Masuda S.: Effect of chloride on the formation of 3monochloro-1, 2-propanediol fatty acid diesters and glycidol fatty acid esters in fish, meats
and acylglycerols during heating. Food. Addit. Contam. A, 36(2): 236-243 (2019).
24) Su H, Sato A, Onoda E, Fujita H, Sakabe S, Akachi S, Oishi S., Abe F, Kanda T,Shimamura Y, Masuda S. and Ohashi N.: Molecular detection and characterization ofp44/msp2 multigene family of Anaplasma phagocytophilum from haemaphysalis longicornis
in Mie prefecture, Japan. Jpn. J. Infect. Dis., 72(3): 199-202 (2019).
◆ Chief Literary Works (2013- Present)
1)

Masuda S, Shimamura Y: Chapter 26. Radioprotactive Effects of Green Tea, Health
Benefits of Green Tea. An Evidence-based Approach, CABI, 220-229 (2017).

2)

Masuda S, Shimamura Y: 10. Radioprotective effects of green tea, Scientific evidence forthe health benefits of green tea, Japan Tea Central Public Interest Incorporated Association,
162-172 (2015).

3) Oguni I and Shimamura Y: 1.3. Anti-bacterial and anti-viral actions, ～Health bnefits ofgreen tea ～ Navigation to functional and mechanistic aspects 2013, World green tea
association, 6-8 (2013).
4) Masuda S, Shimamura Y, Shimoi K, and Kinae N: Radioactive Contamination andRadioprotective Activity of Green Tea, Foods & Food Ingredients Journal of Japan. 218(3):224-233 (2013).

Research objectives
The objective of research is to find the novel methods for controlling pathogenic factors andfoodborne pathogenic bacteria by molecular-based analysis.
◆ Present Research1) Development of novel control methods to reduce food-poisoning
2) Molecular characterization of pathogenic factors of Staphylococcus aureus and genetransfer of staphylococcal toxin3) Molecular characterization of Staphylococcus aureus-derived membrane vesicles

Update: 02/19/2024