33rd International Symposium of Radiation Biology Center, Kyoto University
URL:

http://www.rbc.kyoto-u.ac.jp/cancer_biology/33_RBC_Symposium.html

Main Theme:

Cutting Edge of Radiation and Cancer Biology

Period:Dec 4 – Dec 5, 2017.

Venue:

Hotel Co-op Inn Kyoto < http://www.coopinn.jp/kyoto_e/ >Yanaginobamba St. North of Takoyakushi, Nakagyo-ku, Kyoto, Japan.
Tel: +81-75-256-6600; e-mail: coopinn-k@univcoop.or.jp

Important date:

Abstract:

Oct 31, 2017.

Pre-registration:

Nov 30, 2017.

Registration Fee: Free
Networking/Reception Party:
18:00-20:00, Dec. 4th. in Restaurant PATIO, Hotel Co-op Inn Kyoto.
Pre-registration to the party by non-students: 2,000 JPY.
Pre-registration to the party by students: 0 JPY.
On-site registration to the party: 3,000JPY.
P.S. Note: Every payment will be made by cash on-site
Hosted by:

Radiation Biology Center, Kyoto University, Japan.

Supported by:

Japan Society for the Promotion of Science (JSPS)The Tokyo Biochemical Research Foundation
Japan Aerospace Exploration Agency
Grant-in-Aid for scientific Research on Innovative Area, MEXT Japan, to “Living inSpace”

Organizer:

Hiroshi HARADA, Radiation Biology Center, Kyoto University, Japan.

Organizing Staff: Minoru KOBAYASHI, Radiation Biology Center, Kyoto University, Japan.
Sho KOYASU, Radiation Biology Center, Kyoto University, Japan.
Symposium Secretariat:
Keiko WADA, Radiation Biology Center, Kyoto University, Japan.
Masami TANAKA, Radiation Biology Center, Kyoto University, Japan.
Atsuko YAMADA, Radiation Biology Center, Kyoto University, Japan.
Yukiko SAKAI, Radiation Biology Center, Kyoto University, Japan.
Peng FAN, Radiation Biology Center, Kyoto University, Japan.

1Access
Venue:

Hotel Co-op Inn Kyoto < http://www.coopinn.jp/kyoto_e/ >Yanaginobamba St. North of Takoyakushi, Nakagyo-ku, Kyoto, Japan.

Transportation:
From Airport to JR Kyoto Station <http://www.okkbus.co.jp/en/>●Osaka (Itami) Airport → Limousine bus (50 min, 1,310 JPY) → JR Kyoto Station●Kansai Int’l Airport → Limousine bus (90 min, 2,550 JPY) → JR Kyoto Station

From JR Kyoto Station by train:● Subway: → (Karasuma Line) → Shijo Station → 8 min walk → Hotel Co-op Inn Kyoto● Bus: Bus Stop “#A1” → (Line #5) → Bus Stop “Shijo-Takakura” → 5 min walk → Hotel Co-op Inn Kyoto● Taxi: → 15 min (about 1,500 JPY) →Hotel Co-op Inn Kyoto
Please show the following message to taxi driver.

「ホテル・コープイン京都までお願いします。」
Others:● Hankyu Railway Karasuma Station → 8 min walk → Hotel Co-op Inn Kyoto● Hankyu Railway Kawaramachi Station → 8 min walk → Hotel Co-op Inn Kyoto

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Information for Chairs and Presenters
For Every Speakers in “Keynote Lecture”, “Session 1-4”, and “Short Talk Session”
1. PC Registration
Please come to the “PC Desk” at the left-front of the room during the Coffee Break before the Scientific
Session you will give a talk in, and let the staff connect your own PC to the projector.
2. Presentation Method
Presentations are to be given with your own laptop. Please do not forget to bring your laptop. No soundoutput is available.
3. Official Language
English4. Time Allocation
The chairs and speakers are expected to ensure that all presentations start and finish punctually asscheduled.
Keynote Lecture:

50 min Presentation + 10 min Discussion

Session 1-4:

25 min Presentation + 5 min Discussion

Short Talk Session:

9 min Presentation + 3 min Discussion

Staff will assist chairs and speakers with timing. Remaining time for each presentation will be notified
with bell signals as follows;
1 ring:1 minutes to the end of presentation

2 rings:

End of presentation - Start of discussion

3 rings:

End of discussion - Time for next presentation

5. Technical requirements for your laptop
Please ensure that your computer is equipped with the proper monitor connector (e.g. D-sub 15 pin). The
organizer will prepare following 4 kinds of converters (1) HDMI to VGA (D-sub 15 pin), (2) miini
Displayport to VGA (D-sub 15 pin), (3) USB 3.1 Type C to VGA (D-sub 15 pin) (4) microHDMI to VGA(D-sub 15 pin). If your computer does not have the connection, please bring an appropriate converter withyou.
Please be sure to bring an AC adaptor. Please note that voltage in Japan is 100V and the frequency ranges
50-60 Hz depending on the area (60Hz in Kyoto). The socket is type A, which has two flat plug holes. If
your laptop is not convertible, transformers and/or plug adaptors are necessary.

3Please deactivate the screen-saver and power saving mode of your laptop.
Your laptop will be prepared on the podium for you to operate by yourself.

For Poster Presenters
1. Set up, Presentation/ Discussion, RemovalPlease set up your poster just after you come to the symposium venue. Push pins are prepared by theorganizer.
Please stand by your poster, respond to questions, and enjoy discussion during the following time period
in the Poster Session.
Odd poster number 12:05 – 12:30, Dec. 5th, 2017.
Even poster number 12:30 – 12:55, Dec. 5th, 2017.
Please remove your poster before you leave the symposium venue. The organizer does not keep or return
any of the posters left.
2. Posting Information
2.1. Location
The presentation number is on the upper left of each panel. Please use the panel that matches yourpresentation number.
2.2 Panel size
Each panel space available is 80 cm wide x 120 cm high. Please indicate your presentation title,author(s), and affiliation(s) on top of the poster. Your presentation title, author(s), and affiliation(s) must bewritten big enough to see from 5 meters away.
2.3. Language
Posters are to be written in English.

4Timetable

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Program
Day 1: Dec 4 (Mon), 2017.
12:00-13:00

Registration

13:00-13:10

Opening Remarks
Minoru TAKATA, Kyoto University, Japan

13:10-14:40

Session 1: Radiation Biology and Oncology (Page 10-12)

Session Chair:

Minoru TAKATA, Kyoto University, Japan(13:10-13:40)

Ester M HAMMOND, University of Oxford, UK
Understanding and exploiting the hypoxia-induced DNA damage
response (P10)(13:40-14:10)

Geoffrey S HIGGINS, University of Oxford, UK
Altering oxygen consumption to alleviate tumour hypoxia (P11)(14:10-14:40)

David FERNANDEZ-ANTORAN , Wellcome Trust Sanger Institute,UK
Low-doses of gamma-radiation alter epithelial cell behaviour andpromote mutant clone expansion (P12)

14:40-15:00

Coffee Break

15:00-16:30

Session 2: Cancer Biology (Page 13-15)

Session Chair:

Tomohiro MATSUMOTO, Kyoto University, Japan(15:00-15:30)

Tatsushi IGAKI, Kyoto University, Japan.
Epithelial tumor suppression by cell competition (P13)(15:30-16:00)

Yasuyuki FUJITA, Hokkaido University, Japan.
Cell competition between normal and transformed epithelial cells(P14)(16:00-16:30)

Chiaki TAKAHASHI, Kanazawa University, Japan.
Regulation of metabolism by RB tumor suppressor (P15)

16:30-16:50

Coffee Break

16:50-17:50

Keynote Lecture (Page 9)6

Session Chair:

Hiroshi HARADA, Kyoto University, Japan
Ruth J MUSCHEL, University of Oxford, UK.
The role of macrophages in the tumor response to radiation (P9)

17:50-18:00

Group Photo

18:00-20:00

Networking/Reception Party

Day 2: Dec 5 (Tue), 2017. a
9:00-10:30

Session 3: DNA Damage Response and Repair-1 (Page 16-18)

Session Chair:

Masamichi ISHIAI, Kyoto University, Japan(9:00-9:30)

Hiroyuki SASANUMA, Kyoto University, Japan.
The essential role of Mre11-Rad50-Nbs1 complex in the removal ofabortive Top2-DNA complex (P16)(9:30-10:00)

Orlando D. SCHÄRER, Ulsan National Institute of Science andTechnology, Korea.
Regulation of Dual Incision and Repair Synthesis in Human
Nucleotide Excision Repair (P17)(10:00-10:30)

Kiyoshi MIYAGAWA, The University of Tokyo, Japan.
Regulation of checkpoint strength in the DNA damage response(P18)

10:30-10-50

Coffee Break

10:50-11:50

Short Talk Session (Page 22-26)

Session Chair:

Junya KOBAYASHI, Kyoto University, Japan(10:50-11:02)

Kanji FURUYA, Kyoto University, Japan.
CDK-PLK1 axis targets DNA checkpoint sensor protein RAD9,
promoting tolerance to genotoxic stress and cell proliferation (P22)(11:02-11:14)

Ryotaro NISHI, Ritsumeikan University, Japan.
A deubiquitylating enzyme, UCHL3, enhances non-homologous
end-joining by regulating Ku ubiquitylation (P23)(11:14-11:26)

Atsushi KAIDA, Tokyo Medical and Dental University, Japan.
Determining radiosensitivity of quiescent and proliferating tumor
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cells irradiated under different tumor microenvironments (P24)(11:26-11:38)

Yusuke OKAMOTO, Kyoto University, Japan.
Replication stress induces R-loop-dependent accumulation ofFANCD2 at large fragile genes (P25)(11:38-11:50)

Eiichiro MORI, Nara Medical University, Japan.
Effects of aliphatic alcohols on labile amyloid-like cross-β polymers
formed from low complexity domain of fused in sarcoma (FUS)(P26)

11:50-12:00

Short Break

12:00-13:00

Poster Session with Lunch (Page 27-47)

13:00-14:30

Session 4: DNA Damage Response and Repair-2 (Page 19-21)

Session Chair:

Tsuyoshi IKURA, Kyoto University, Japan(13:00-13:30)

Kyungjae MYUNG, Ulsan National Institute of Science and Technology,Korea.
Molecular mechanisms of DNA repair (P19)(13:30-14:00)

Natsuko CHIBA, Tohoku University, Japan.
BRCA1-interacting protein OLA1 is involved in the centrosomal
duplication and response to DNA damage (P20)(14:00-14:30)

Akira YASUI, Tohoku University, Japan.
Frequent defect in the nucleosome remodeling complexes belonging
to SWI/SNF family significantly reduces DNA repair and otheractivities, leading to cell death and tumorigenesis (P21)

14:30-14:40

Closing Remarks
Hiroshi HARADA, Kyoto University, Japan.

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