Poster Presentations
P-001–042: October 20 (Wednesday) 18:15–19:15
P-001

Dynamic kinetic resolution of amino acids using four Ni(II) chiral Schiff bases
Arina Nakano1, Keita Nagaoka1, Jianlin Han2, Tsubasa Sakamoto3, Hiroki Moriwaki3, Hidenori Abe3,
Kunisuke Izawa3, Vadim A. Soloshonok4, Hiroyuki Konno1 (1Graduate School of Science andEngineering, Yamagata University, 2College of Chemical Engineering, Nanjing Forestry University,
3

Hamari Chemicals Ltd., 4Department of Organic Chemistry I, Faculty of Chemistry, University of

the Basque Country UPV/EHU)
P-002

Study for chemical synthesis of nanobody
Kazuki Ichihashi, Yuya Asahina, Hironobu Hojo (Institute for Protein Research)

P-003

Modular synthesis of disulfide cross-linked HIV-1 protease analogue using 4-fluorophenyl 3-nitro2-pyridinesulfenate (Npys-OPh(pF))
Yan Cui1, Akihiro Taguchi1, Hayate Shida1, Kiyotaka Kobayashi1, Sho Konno1, Kentaro Takayama1,2,
Atsuhiko Taniguchi1, Yoshio Hayashi1 (1Department of Medicinal Chemistry, Tokyo University of
Pharmacy and Life Sciences, 2Department of Environmental Biochemistry, Kyoto Pharmaceutical
University)

P-004

On-resin redox catalysts utilizing selenopeptides
Kasumi Abe, Masaki Kuroda, Michio Iwaoka (Tokai University)

P-005

Development of phosphine ligands with helical peptide for enantioselective [3+2]cycloaddition
reactions
Ryoma Nishioka1, Tomohiro Umeno1, Mitsunobu Doi2, Takuma Kato2, Atsushi Ueda1, Makoto Oba3,
Masakazu Tanaka1 (1Graduate School of Biomedical Sciences, Nagasaki University, 2Osaka Medical
and Pharmaceutical University, 3Kyoto Prefectural University of Medicine)

P-006

Effect of cis-trans transformation of benzanilide derivatives on peptide conformation
Asami Ichinose, Yuko Otani, Tomohiko Ohwada (Graduate School of Pharmaceutical Sciences, The
University of Tokyo)

P-007

Synthesis and structural characterization of β-turn mimics containing (Z)-chloroalkene dipeptide
isosteres
Yuki Kodama, Kohei Sato, Nobuyuki Mase, Tetsuo Narumi (Graduate School of Science andTechnology, Shizuoka University)

P-008

Diastereoselective synthesis of a highly functionalized (Z)-chloroalkene dipeptide isostere of LeuDap dipeptide
Daichi Toyama1, Yuki Kodama2, Junko Fujimoto3, Kohei Sato1,2,3, Nobuyuki Mase1,2,3, Kentaro
Takayama4, Tetsuo Narumi1,2,3 (1Graduate School of Integrated Science and Technology, Shizuoka
University, 2Graduate School of Science and Technology, Shizuoka University, 3Faculty ofengineering, Shizuoka University, 4Kyoto Pharmaceutical University)

P-009

Synthetic study toward the chemical synthesis of closed structure mimics of K63-linked ubiquitin
dimer with 1,2,3-triazole-tethered ubiqutin linkage region
Reon Takeuchi, Kohei Sato, Nobuyuki Mase, Tetsuo Narumi (Graduate School of Science andTechnology, Shizuoka University)
P-010

K48/K63 branched ubiquitin chain: chemical synthesis and interactome analysis
Yoshinori Taguchi1, Takuya Tomita2, Fumiaki Ohtake3, Kohei Sato1, Nobuyuki Mase1, Yasushi Saeki2,
Tetsuo Narumi1 (1Department of Engineering, Graduate School of Integrated Science and Technology,
Shizuoka University, 2Laboratory of Protein Metabolism, Tokyo Metropolitan Institute of Medical
Science, 3Institute for Advanced Life Sciences, Hoshi University)

P-011

Identification of G4-biniding peptide molecules from the RGG3 domain of translocated inliposarcoma/fused in sarcoma
Sayuri Takeo1, Maiko Tabata2, Yuki Kodama3, Kohei Sato1,3, Nobuyuki Mase1,3, Takanori Oyoshi2,3,
Tetsuo Narumi1,3 (1Department of Engineering, Graduate School of Integrated Science andTechnology, Shizuoka University, 2Department of Science, Graduate School of Integrated Science andTechnology, Shizuoka University, 3Graduate School of Science and Technology, Shizuoka University)

P-012

Total synthesis of nicrophorusamide A and B, antibacterial cyclic peptides
Yuto Katayama, Minoru Inagaki, Yuichi Masuda (Graduate School of Bioresources, Mie University)

P-013

Synthesis of β-hydroxy amino acids constituting hypeptin, an antimicrobial cyclodepsipeptide
Kazuki Hashizume, Tsubasa Itoh, Takahiro Aimi, Minoru Inagaki, Yuichi Masuda (Graduate Schoolof Bioresources, Mie University)

P-014

In vitro selection of prenylated macrocyclic peptides using a cyanobactin biosynthsis enzyme
Sumika Inoue, Rika Okuma, Yuki Goto, Hiroaki Suga (Department of Chemistry, Graduate School of
Science, The University of Tokyo)

P-015

Physiological roles of mitocryptide-3 and its derivatives in mitochondrial damage associatedmolecular patterns
Yosinori Sugimoto, Hiroki Morikawa, Takayuki Marutani, Yoshiaki Kiso, Hidehito Mukai(Laboratory of Peptide Science, Graduate School of Bio-Science, Nagahama Institute of Bio-Scienceand Technology)

P-016

Synthesis of fucosylated glycopeptide by a novelprotection scheme of sugar alcohols
Tatsuya Ando1,2, Yuya Asahina1, Hironobu Hojo1 (1Institute for Protein Research, Osaka University,
2

P-017

Graduate School of Science, Osaka University)

Trityl type solubilizing tag including trimethyllysine for preparing hydrophobic peptides
Shun Masuda, Shugo Tsuda, Taku Yoshiya (Peptide Institute, Inc.)

P-018

A reversible method for the detection of amines groups during solid-phase peptide synthesis
Tomohiro Umeno, Kazuteru Usui, Satoru Karasawa (Faculty of Pharmaceutical Sciences, Showa
Pharmaceutical University)

P-019

Development of one-pot synthesis of cyclic disulfide peptide using water-soluble Npys derivative
Megumi Sakata1, Akihiro Taguchi1, Saeka Kuraishi1, Sho Konno1, Kentaro Takayama1,2, Atsuhiko
Taniguchi1, Yoshio Hayashi1 (1School of Pharmacy, Tokyo University of Pharmacy and Life Sciences,
2

P-020

Kyoto Pharmaceutical University)

Synthesis of peptide selenoester through diketopiperazine formation for efficient peptide ligation
Masaya Hashimoto, Koki Nakatsu, Gosuke Hayashi, Hiroshi Murakami (Graduate School ofEngineering, Nagoya University)P-021Synthesis of dual-mono ubiquitinated PAF15 for elucidation of maintenance methylation
mechanism
Yuya Takahashi1, Satomi Kori2, Kyohei Arita2, Gosuke Hayashi1, Hiroshi Murakami1 (1Nagoya
University, 2Yokohama City University)

P-022

One-pot disulfide-driven cyclic peptide synthesis of oxytocin using 4-fluorophenyl 3-nitro-2pyridinesulfenate (Npys-OPh(pF))
Hayate Shida1, Akihiro Taguchi1, Kiyotaka Kobayashi1, Yan Cui1, Sho Konno1, Kentaro Takayama1,2,
Atsuhiko Taniguchi1, Yoshio Hayashi1 (1School of Pharmacy, Tokyo University of Pharmacy and Life
Sciences, 2Department of Environmental Biochemistry, Division of Biological Sciences, Kyoto
Pharmaceutical University)

P-023

Expanded late-stage solubilization of peptide hydrazide applicable to subsequent ligation
Shoko Tanaka1, Kohei Sato1,2, Tetsuo Narumi1,2,3, Nobuyuki Mase1,2,3 (1Graduate School of Scienceand Technology, Shizuoka University, 2Graduate School of Integrated Science and Technology,
Shizuoka University, 3Research Institute of Green Science and Technology, Shizuoka University)

P-024

Residue-specific modification reaction using S-acetamidomethyl cysteine sulfoxide, Cys(Acm)(O)
Kaito Anzaki1, Kento Ohkawachi1, Daishiro Kobayashi1, Ryuji Kyan2, Masaya Denda1, Akira
Shigenaga2, Akira Otaka1 (1Institute of Biomedical Sciences and Graduate School of Pharmaceutical
Sciences, Tokushima University, 2Faculty of Pharmacy and Pharmaceutical Sciences, Fukuyama
University)

P-025

Overexpression of a human antimicrobial peptide LL-37 and its orthologs using novel calmodulin
fusion system
Mitsuki Shibagaki1, Waka Ueda1, Kohei Kano2, Hao Gu2, Tomoyasu Aizawa1,2,3 (1School of Science,
Hokkaido University, 2Graduate School of Science, Hokkaido University, 3Faculty of Advanced Life
Science, Hokkaido University)

P-026

Oligo(N-methylalanine) as a molecular scaffold for designing protein ligands
Marin Yokomine1, Daisuke Kuroda1, Takumi Ueda2, Koh Takeuchi3, Kouhei Tsumoto1,4,

JumpeiMorimoto1, Shinsuke Sando1 (1Graduate School of Engineering, The University of Tokyo, 2Graduate
School of Pharmaceutical Sciences, The University of Tokyo, 3Cellular and Molecular Biotechnology
Research Institute, National Institute of Advanced Industrial Science and Technology, 4Institute ofMedical Science, The University of Tokyo)
P-027

Construction of β-barreled peptide nanopores by cell-free expression
Shoko Fujita, Miyu Fukuda, Ikuro Mizoguchi, Ryuji Kawano (Department of Biotechnology and Life
Science, Tokyo University of Agriculture and Technology)

P-028

Synthesis of macrocycles by peptide catalyst with a nitrogen-containing cyclic α,α-disubstituted αamino acid
Yuto Yamaberi1, Tomohiro Umeno1, Atsushi Ueda1, Makoto Oba2, Masakazu Tanaka1 (1Graduate
School of Biomedical Sciences, Nagasaki University, 2Graduate School of Medicine, Kyoto
Prefectural University of Medicine)

P-029

Single-molecule detection of polypeptides using monodisperse β-barrel nanopore
Ikuro Mizoguchi1, Masataka Usami1, Keisuke Shimizu1, Taichi Isozaki2, Yoshio Hamada2, KenjiUsui2, Ryuji Kawano1 (1Department of Biotechnology and Life Science, Tokyo University ofAgriculture and Technology, 2Faculty of Frontiers of Innovative Research in Science and Technology,
Konan University)
P-030

Signaling mechanisms for mitocryptids derived from mitochondrial transit sequences inneutrophlilc cells
Koji Ohura, Takayuki Marutani, Ryota Tanemura, Takumi Sasaki, Shinichiro Tamura, Kenta
Nakashima, Yoshiaki Kiso, Hidehito Mukai (Laboratory of Peptide Science, Graduate School of BioScience, Nagahama Institute of Bio-Science and Technology, Nagahama, Shiga)

P-031

Interaction of mitocryptide-2 and its derivatives with formyl peptide receptor 2 for the neutrophilic
activation
Hiroki Hirai, Takayuki Marutani, Kodai Nishino, Yoshiaki Kiso, Hidehito Mukai (Laboratory ofPeptide Science, Graduate School of Bio-Science, Nagahama Institute of Bio-Science andTechnology)

P-032

Development of helical antimicrobial peptides containing non-proteinogenic amino acids
Motoharu Hirano1,2, Chihiro Saito3, Ryuji Kawano3, Takashi Misawa2, Yosuke Demizu1,2 (1Graduate
School of Medical Life Science, Yokohama City University, 2 National Institute of Health Sciences,
3

P-033

Department of Biotechnology and Life Science, Tokyo University of Agriculture and Technology)

Analysis of oligomerized bioactive peptides for eukaryotic and prokaryotic cells
Yuna Nunokawa, Shuya Sakaguchi, Rui Kamada, Kazuyasu Sakaguchi (Laboratory of Biological
Chemistry, Department of Chemistry, Faculty of Science, Hokkaido University)

P-034

Utility verification of screening method of membrane-permeable cyclic peptides
Yusuke Inoue, Minoru Inagaki, Yuichi Masuda (Graduate School of Bioresources, Mie University)

P-035

Withdrawal

P-036

Peptide length optimization of lysine-specific demethylase 1 inhibitors
Masaki Asakawa1, Taeko Kakizawa1, Takayoshi Suzuki2 (1Graduate School of Materials and Life
Sciences, Kanto Gakuin University, 2The Institute of Scientific and Industrial Research, Osaka
University)

P-037

PURE system-based mRNA display evolution of unnatural cyclic peptides via genetic code
expansion for allergic disease treatment
Daisuke Fuji1,2, Yuta Shiojima1,3, Takumi Yokoyama1,2, Takehiro Ando1,4, Mizuki Yamamoto1,4,
Takashi Kawakami1,5,6 (1University of Yamanashi, 2Department of Life and Environmental Sciences,
Integrated Graduate School of Medicine, Engineering and Agricultural Sciences, 3Department of
Biotechnology, Faculty of Life and Environmental Sciences, 4Department of Integrated Applied Life
Science, Integrated Graduate School of Medicine, Engineering, and Agricultural Sciences, 5Faculty ofLife and Environmental Sciences, Graduate Faculty of Interdisciplinary Research, 6JST, PRESTO)

P-038

Construction of cyclic peptide library containing aryl fluorosulfate warhead on T7 phage
Riku Katsuki, Yudai Tabuchi, Masumi Taki (The university of electro-communication)

P-039

Physiological significance of different receptor selectivities between FPR2 and FPR1 formitocryptide-2 and its derivatives depending on their molecular forms
Tomoyuki Miyaji, Takayuki Marutani, Kodai Nishino, Yoshito Takamuro, Takenori Yamada, HirokiMorikawa, Tatsuya Hattori, Yoshiaki Kiso, Hidehito Mukai (Laboratory of Peptide Science, Graduate
School of Bio-Science, Nagahama Institute of Bio-Science and Technology)
P-040

Activation mechanisms of neutrophils stimulated by mitochondrial transit signal sequences
including mitocryptide-3
Ryota Tanemura, Takayuki Marutani, Koji Ohura, Yoshiaki Kiso, Hidehito Mukai (Laboratory ofPeptide Science, Graduate School of Bio-Science, Nagahama Institute of Bio-Science andTechnology)

P-041

Peptide stapling improves the sustainability of a peptide-based degraders against estrogen receptors
Hidetomo Yokoo1,2, Nobumichi Ohoka2, Takahito Ito2, Makoto Oba1, Takao Inoue2, Mikihiko Naito3,
Yosuke Demizu2 (1Kyoto Prefectural University of Medicine, 2National Institute of Health Sciences,
3

P-042

The University of Tokyo)

CEACAM3 splicing is altered by PPM1D inhibition in HL-60 cells
Tatsuya Kodama, Shoma Kura, Fuki Kudoh, Kei Kawamura, Kazuyasu Sakaguchi, Rui Kamada(Laboratory of Biological Chemistry, Department of Chemistry, Faculty of Science, Hokkaido
University)

P-043–084: October 21 (Thursday) 17:20–18:20
P-043

Evaluation of the peptide derived from the N- and C-terminal regions of kinase domain for allostericcontrol of receptor tyrosine kinase cMet
Yuki Tanaka1, Takayoshi Kinoshita1, Kunio Matsumoto2 (1Graduate School of Science, Osaka
Prefecture University, 2Cancer Research Institute, Kanazawa University)

P-044

Synthesis of biotin-labeled probes of a cyclic pentapeptide PF1171B for identification of its target
molecules
Taiga Oda, Minoru Inagaki, Yuichi Masuda (Graduate School of Bioresources, Mie University)

P-045

Development of a novel in vitro screening system for backbone macrocyclic peptides
Koki Shinbara, Ryo Takatsuji, Takayuki Katoh, Hiroaki Suga (Department of Chemistry, Graduate
School of Science, The University of Tokyo)

P-046

Screening of drug candidates from cyclic β-amino acid-containing helical peptide library
Marina Kawai1, Takayuki Katoh1, Toru Sengoku2, Hiroaki Suga1 (1Department of Chemistry, Graduate
School of Science, The University of Tokyo, 2Department of Biochemistry, Graduate School of
Medicine, Yokohama City University)

P-047

Fluorescent silica nanoparticles modified with cell-penetrating peptides toward a drug delivery
carrier
Daiki Kawahara, Ukyo Matsuura, Ryota Kawawaki, Takayuki Miki, Hisakazu Mihara, Hiroshi
Tsutsumi (School of Life Science and Technology, Tokyo Institute of Technology)

P-048

Photothermal therapeutic effects of polyhistidine peptide-modified gold nanoparticles
Kosuke Hori, Tsuyoshi Kawano, Takashi Iwasaki (Graduate School of Sustainability Science, Tottori
University)P-049Effect of microwave irradiation on cellular uptake using arginine-rich peptide
Momo Hirata1, Yonejiro Arimoto2, Ryuji Osawa3, Nobuhiro Nakanishi4, Kenji Usui1 (1Graduate
School of Frontiers of Innovative Research in Science and Technology (FIRST), Konan University,
2

Minato Medical Science Co. Ltd., 3Seikoh Giken Co. Ltd., 4DSP Research, Inc.)

P-050

Withdrawal

P-051

Development of amphiphilic YK peptide tags for bottom-up construction of liquid-liquid phaseseparation
Hiroki Takahashi, Takayuki Miki, Taichi Nakai, Masahiro Hashimoto, Hisakazu Mihara (School ofLife Science and Technology, Tokyo Institute of Technology)

P-052

Construction of photoreactive group-modified phage libraries and selection against hDM2
Keigo Namii, Takayuki Miki, Hisakazu Mihara (School of Life Science and Technology, Tokyo
Institute of Technology)

P-053

Polymer binding peptide as a molecular tool for cell imaging
Chihiro Inaba1, Toshiki Sawada1, Tetsuya Kadonosono2, Takeshi Serizawa1 (1School of Materials andChemical Technology, Tokyo Institute of Technology, 2School of Life Science and Technology, Tokyo
Institute of Technology)

P-054

Development of therapeutic antibody-modified nanobubbles using Fc-binding peptide and theiranti-cancer effects with therapeutic antibody
Yusuke Yano1, Kenshin Haruta1, Nobuhito Hamano1, Yamato Kikkawa1, Yoko Endo-Takahashi1,
Motoyoshi Nomizu1, Ryo Suzuki2, Kazuo Maruyama2, Yoichi Negishi1 (1School of Pharmacy, Tokyo
University of Pharmacy and Life Sciences, 2School of Pharmacy, Teikyo University)

P-055

A non-transgenic plant genome editing method using cell-penetrating peptides: polyhistidine
peptidesYoshino Tanaka1, Yoshihiko Nanasato2, Kousei Omura1, Tsuyoshi Kawano1, Keita Endoh3, Takashi
Iwasaki1 (1Department of Agriculture, Graduate School of Sustainability Science, Tottori University,
2

Forest Bio-Research Center, Forestry and Forest Products Research Institute, 3Forest Tree Breeding

Center, Forestry and Forest Products Research Institute)
P-056

Synthesis and property of water-soluble cyclic peptides modified with two pyrenyl groups
Sora Sakura, Yuhi Maekawa, Mizuki Kitamatsu (Kindai University)

P-057

Identification of RGD-containing sequences that promote induced pluripotent stem cell adhesion
Toru Onda, Yuji Yamada, Ayami Hagiuda, Keisuke Hamada, Yamato Kikkawa, Motoyoshi Nomizu(School of Pharmacy, Tokyo University of Pharmacy and Life Sciences, Hachioji)

P-058

Integration of phthalocyanine into self-assembling peptides nanostructures
Sohma Hizawa, Takayouki Miki, Hisakazu Mihara, Hiroshi Tsutsumi (School of Life Science andTechnology, Tokyo Institute of Technology)

P-059

Construction of circularly permutated soybean peroxidase
Taisei Iwabuchi, Tsuyoshi Takahashi (Graduate School of Science and Technology, Gunma
University)

P-060

Development of temperature-responsive peptides by EDTA-mediated multimerization of short(FPGVG)n chainsNaoki Tanaka1, Keitaro Suyama2, Keisuke Tomohara2, Iori Maeda3, Takeru Nose1,2 (1Department ofChemistry, Faculty and Graduate School of Science, Kyushu University, 2Faculty of Arts and Science,
Kyushu University, 3Department of Physics and Information Technology, Kyushu Institute ofTechnology)
P-061

Creation of artificial E3s with specific E2-binding capabilities by amino acid replacements
Ayumi Fukuda, Kazuhide Miyamoto (Pharmaceutical Sciences, Sanyo-Onoda City University)

P-062

Regulatory mechanism of larval diapause by C. elegans neuropeptide, FLP-6, in intestine
Masahiro Ono1, Yohei Matsunaga2, Tomohiro Bito1, Takashi Iwasaki1, Tsuyoshi Kawano1(1Department of Bioresources Science, The United Graduate School of Agriculture, Tottori University,
2

P-063

SRL)

Regulatory mechanism of larval development by a C. elegans neuropeptide, FLP-3
Masayo Nose1, Natsumi Kageyama1, Yohei Matsunaga2, Takashi Iwasaki1, Tsuyoshi Kawano1(1Department of Agricultural Science, Graduate School of Sustainability Science, Tottori University,
2

P-064

SRL)

Development of antibody-mimetic small proteins targeting tumor-associated phosphatase PPM1D
Megumi Ikeura1, Hiroto Tashiro1, Junki Shinada1, Kazuhiro Furukawa2, Yoshiro Chuman1(1Laboratory of Biological Chemistry, Graduate School of Science and Technology, Niigata University,
2

Cell Regulation Laboratory in Biochemistry, Graduate School of Science and Technology, Niigata

University)
P-065

Identification of inhibitors for disease-related phosphatase Scp1 using antibody-like adnectin
Junki Shinada1, Kazuki Yamazaki1, Megumi Ikeura1, Kazuhiro Furukawa2, Yoshiro Chuman1(1Laboratory of Biological Chemistry, Graduate School of Science and technology, Niigata University,
2

Cell Regulation Laboratory in Biochemistry, Graduate School of Science and technology, Niigata

University)
P-066

Neuropeptide gene expression in the fetal mouse brain exposed to an endocrine-disrupting chemical
Mari Hosose1, Kyota Shirane1, Tomoka Ishibashi1, Kotone Ito1, Koki Tagawa1, Ayami Matsushima1,2(1Department of Chemistry, Graduate School of Science, Kyushu University, 2Department ofChemistry, Faculty of Science, Kyushu University)

P-067

Synthesis of novel cyclic peptides for inclusion of polypeptides and characterization of their
inclusion ability
Taichi Kurita1, Joan Gimenez-Dejoz2, Seiya Fujita1, Hirotaka Uji1, Keiji Numata1,2 (1Graduate Schoolof Engineering, Kyoto University, 2RIKEN Center for Sustainable Resource Science)

P-068

Anti-nucleation peptide screened from a phage displayed peptide library
Sora Okamoto1, Seijiro Matsuki1, Yoshio Katakura1,2, Yoshiaki Hirano1,2 (1Faculty of Chemistry,
Materials and Bioengineering, Kansai University, 2Organization for Research and Development of
Innovative Science and Technology, Kansai University)

P-069

De novo discovery of macrocyclic peptide ligands containing N-alkyl amino acids
Naoya Kawakami, Toby Passioura, Naohiro Terasaka, Hiroaki Suga (Department of Chemistry,
Graduate School of Science, The University of Tokyo)

P-070


Density functional theory study of the mechanism of amide bond formation of amino acid-derived
active esters
Junko Fujimoto1, Kohei Sato1,2, Nobuyuki Mase1,2, Tetsuo Narumi1,2 (1Faculty of Engineering,
Shizuoka University, 2Department of Engineering, Graduate School of Integrated Science andTechnology)
P-071

Ser/Thr phosphatase PPM1D regulates neutrophil-differentiation and subset polarization
Shoma Kura, Tatsuya Kodama, Fuki Kudoh, Kazuyasu Sakaguchi, Rui Kamada (Laboratory of
Biological Chemistry, Department of Chemistry, Faculty of Science, Hokkaido University)

P-072

Optimization of HPLC columns in peptide analysis with ColumnViewer software and optimizationof separation with OffLine software
Masaaki Suzuki, Yuko Aoki, Shigenori Sonoki, Kazuhide Konishi (Chromsword Japan Co., Ltd.)

P-073

Regulation of amyloid fibrillation by high-power terahertz waves
Takayasu Kawasaki1, Yuusuke Yamaguchi2, Hideaki Kitahara2, Akinori Irizawa3, Masahiko Tani2(1Accelerator Laboratory, High Energy Accelerator Research Organization, 2Research Center for
Development of Far-Infrared Region, University of Fukui, 3The Institute of Scientific and Industrial
Research, Osaka University)

P-074

Withdrawal

P-075

Photoreaction-induced SDS-resistant PrPSc/res oligomer formation
Kenta Teruya, Toshiya Ishikawa, Sara Iwabuchi, Miki Watanabe-Matsui, Katsumi Doh-ura (Tohoku
University, Graduate School of Medicine)

P-076

PreQ1 facilitates DNA strand invasion by PNA
Shun-suke Moriya1, Yuki Yoneta1, Keiko Kuwata2, Yasutada Imamura3, Yosuke Demizu4, Masaaki
Kurihara5, Atsushi Kittaka1, Toru Sugiyama1 (1Faculty of Pharma-Sciences, Teikyo University,
2

Institute of Transformative Bio-Molecules (WPI-ITbM), Nagoya University, 3School of Advanced

Engineering, Kogakuin University, 4Division of Organic Chemistry, National Institute of Health
Sciences, 5Department of Pharmaceutical Sciences, International University of Health and Welfare)
P-077

Broad substrate tolerance of an engineered aryl acid adenylation domains with an enlarged
substrate binding site
Fumihiro Ishikawa, Maya Nohara, Natsuki Miyano, Kana Kinoshita, Hinano Kitayama, Katsuki
Takashima, Genzoh Tanabe (Faculty of Pharmacy, Kindai University)

P-078

Cloning and enzyme activation of a saliva protease derived from Nephila Clavata
Misaki Nishimura1, Ayumi Ogata1, Teruki Hagiwara1, Mitsuhiro Miyazawa2, Shigeru Shimamoto1,
Yuji Hidaka1 (1Graduate School of Science and Engineering Research, Kindai University, 2Institute ofAgrobiological Sciences, National Agriculture and Food Research Organization)

P-079

Maturation of the disulfide-coupled folding of prouroguanylin in molecular evolution
Koki Mizoe, Ryota Shinto, Masaya Goto, Kota Fujiwara, Shigeru Shimamoto, Yuji Hidaka (Graduate
School of Science and Engineering Research, Kindai University)

P-080

Preparation of mutant proteins of the cystatin-related epididymal spermatogenic protein
Sayuri Murata, Shigeru Shimamoto, Yuji Hidaka (Graduate School of Science and Engineering
Research, Kindai University)

P-081


Structural analyses of a linker region of the pathogenic amyloid precursor protein
Yusaku Hanagaki1, Shingo Kanemura1, Masaki Okumura1, Hiroshi Yamaguchi1, Shigeru Shimamoto1,
Yuji Hidaka1 (1Graduate School of Science and Engineering Research, Kindai University, 2School of
Science and Technology, Kwansei Gakuin University, 3Frontier Research Institute for Interdisciplinary
Sciences)
P-082

Disulfide-coupled folding of de novo designed eel prouroguanylin protein
Ryota Shinto, Koki Mizoe, Masaya Goto, Norie Nakajima, Shigeru Shimamoto, Yuji Hidaka(Graduate School of Science and Engineering Research, Kindai University)

P-083

Mutational analyses of the enzymatic activities of a Bombyx mori cocoonase
Ayumi Ogata1, Misaki Nishimura1, Nana Sakata1, Mitsuhiro Miyazawa2, Shigeru Shimamoto1, Yuji
Hidaka1 (1Graduate School of Science and Engineering Research, Kindai University, 2Institute ofAgrobiological Sciences, National Agriculture and Food Research Organization)

P-084

Synthesis of immobilized gold nanoparticles with catalytic activity using resin conjugated with gold
mineralizing peptide
Shuhei Yoshida, Takaaki Tsuruoka, Kenji Usui (Graduate School of Frontiers of Innovative Researchin Science and Technology (FIRST), Konan University)

P-085–125: October 22 (Friday) 11:20–12:20
P-085

Remineralization potential of bioactive glass and foldamer-based peptides on enamel
Enrique Ezra Zuniga Heredia1, Fernando Arteaga Arteaga2,3, Masaya Sawamura2, Masahiro Iijima1(1Division of Orthodontics and Dentofacial Orthopedics, Health Sciences University of Hokkaido,
2

School of Sciences, Hokkaido University, 3Institute for the Advancement of Higher Education,

Hokkaido University)
P-086

Amine-selective reaction of 2H-azirine for synthesis of peptidemimetics
Hiroto Takahashi1, Makoto Roppongi2, Shingo Tamesue1, and Toru Oba1 (1Department of Materialand Environmental Chemistry, Graduate School of Engineering, Utsunomiya University, 2Advanced
Instrumental Analysis Department, Utsunomiya University)

P-087

Functional analysis of cell-aggregate inducing peptide
Ikumi Amimoto1, Rino Watanabe1, Yoshiaki Hirano1,2 (1Faculty of Chemistry, Materials andBioengineering, Kansai University, 2Organization for Research and Development of Innovative
Science and Technology, Kansai University)

P-088

Artificially designed α-helical peptide nanofibers showing liquid-crystal like thermal behavior
Minami Kurokawa1, Mika Hirose2, Akihiro Kawamoto2, Atsuo Tamura1 (1Grad. Sch. Sci., Univ. Kobe.,
2

P-089

IPR, Osaka Univ.)

Development of temperature-responsive short-chain peptide analogues based on elastin-like
peptide FPGVG
Keitaro Suyama1, Shogo Sumiyoshi2, Naoki Tanaka2, Takumi Ando2, Akihiko Nagata3, Keisuke
Tomohara1, Suguru Taniguchi4, Iori Maeda4, Takeru Nose1,2 (1Faculty of Arts and Science, Kyushu
University, 2Department of Chemistry, Faculty and Graduate School of Science, Kyushu University,3

Department of Chemistry, Faculty of Science, Kyushu University, 4Department of Physics andInformation Technology, Kyushu Institute of Technology)
P-090

Synthesis of two pyrene-modified peptide nucleic acid probes and detection of DNA and by theprobes
Koki Ishii, Sakura Tsuchitani, Miyu Toyama, Mizuki Kitamatsu (Graduate School of Science andEngineering, Kindai University)

P-091

Peptide conjugated microspheres newly designed from hepatitis E virus ORF2 capsid protein to
improve their reactivity against sera from wild boars
Hiroyuki Oku1, Kaito Takeda1, Yuya Tatsumi2, Yuko Oku2 (1Graduate School of Science &Engineering, Gunma University, 2Aoi-Tori Family Clinic)

P-092

Nanotube formation of amphiphilic polypeptide having hydrophobic helix composed of repeated
Leu-Aib sequence
Abosheasha Mohammed1,2, Toru Itagaki1, Yoshihiro Ito1,2,3, Motoki Ueda1,3 (1RIKEN Cluster for
Pioneering Research, 2Tokyo Metropolitan University, 3RIKEN Center for Emergent Matter Science)

P-093

Fluorescent PPI-visualization for the inhibitory activity of helix-loop-helix peptides against p53HDM2 interaction
Daisuke Fujiwara, Kazunori Zikihara, Ryohei Konda, Shunsuke Inaura, Hidekazu Kitada, Masataka
Michigami, Ikuhiko Nakase, Ikuo Fujii (Department of Biological Science, Graduate School of
Science, Osaka Prefecture University)

P-094

A FRET-based assay system for protein kinase C ligand screening using 1,2-diacylglycerol-lactone
derivative
Kohei Tsuji, Takahiro Ishii, Takuya Kobayakawa, Nami Ohashi, Wataru Nomura, Hirokazu Tamamura(Institute of Biomaterials and Bioengineering, Tokyo Medical and Dental University (TMDU))

P-095

De novo designed Aβ14-23 peptidomimetics combat amyloidogenic stress induced cellular toxicity
and stiffness
Debasis Ghosh, Mouli Konar, Sourav Samanta, Thimmaiah Govindaraju (Bioorganic Chemistry
Laboratory, New Chemistry Unit and School of Advanced Materials (SAMat), Jawaharlal Nehru
Centre for Advanced Scientific Research)

P-096

Effects of replacing the Glu residues of Pep-1 peptide with hydrophobic amino acids
Takuma Kato, Hiroaki Numa, Mihoko Nakamachi, Akiko Asano, Mitsunobu Doi (Faculty of
Pharmacy, Osaka Medical and Pharmaceutical University)

P-097

A discovery of novel bioactive peptides from rice protein controlling ghrelin release
Kentaro Kaneko1, Yuki Tokuyama1, Eriko Taniguchi1, Shimon Abe1, Junya Nakato1, Hiroshi Iwakura2,
Masaru Sato3, Atsushi Kurabayashi3, Hideyuki Suzuki3, Akira Ito4, Yuki Higuchi4, Ryoko Nakayama4,
Kimiko Uchiyama4, Hajime Takahashi4, Kousaku Ohinata1 (1Division of Food Science andBiotechnology, Graduate School of Agriculture, Kyoto University, 2First Department of Medicine,
Wakayama Medical University, 3Department of Applied Genomics, Kazusa DNA Research Institutes,
4

P-098

Rice Research Institute, Kameda Seika CO., LTD.)

The docking simulation of the 23-mer inhibitory peptide to myostatin
Tomo Asari1, Hiroaki Ikeyama1, Akihiro Taguchi1, Atsuhiko Taniguchi1, Yoshio Hayashi1, Kentaro
Takayama1,2 (1Department of Medicinal Chemistry, Tokyo University of Pharmacy and Life Sciences,





2

P-099

Department of Environmental Biochemistry, Kyoto Pharmaceutical University)

Fragment-matching survey for amyloid-core region of amyloid-β (1-42)
Hisayuki Morii, Masayuki Nara (Department of Chemistry, College of Liberal Arts and Sciences,
Tokyo Medical and Dental University)

P-100

Peptide library synthesis and enzymatic digestion for future drug design
Reo Yamada, Norimasa Takasu, Masaki Midorikawa, Ren Fujii, Taeko Kakizawa (College of Scienceand Engineering, Kanto Gakuin University)

P-101

Conjugates of MAP(Aib) and cRGD through disulfide linkages as siRNA carriers
Shun-ichi Wada, Makoto Kusuyama, Junsuke Hayashi, Hidehito Urata (Department of Bioorganic
Chemistry, Faculty of Pharmacy, Osaka Medical and Pharmaceutical University)

P-102

Substituted indolizidinone peptidomimetic modulators of the prostaglandin-F2α receptor
Ramakotaiah Mulamreddy, Christiane Quiniou, Xin Hou, Sylvian Chemtob, William D. Lubell(University of Montreal)P-103

Hybrid molecules of CD4 mimic and HIV-1 gp41-related peptides as fusion inhibitors
Rongyi Wang1, Kohei Tsuji1, Yishan Liu1, Takuya Kobayakawa1, Shigeyoshi Harada2, Hirokazu
Tamamura1 (1Institute of Biomaterials and Bioengineering, Tokyo Medical and Dental University,
2

P-104

AIDS Research Center, National Institute of Infectious Diseases)

Investigation of the antimicrobial activity, cell viability and emolytic activity of N-fatty acylated
myticalin A6 (3-23)-OH derivatives
Keiko Okimura, Tatsuo Takahashi, Atsuya Sawada, Chinami Katsui, Tamako Shiratori, Risa Sugita,
Sayuri Suzuki, Tohru Daikoku (Faculty of Pharmaceutical Sciences, Hokuriku University)

P-105

Synthesis of oxytocin analogues focused on the hydrophobic structures and their positive allostericmodulator effect on µ opioid receptor
Takaaki Mizuguchi1, Risa Yamauchi1, Haruka Ono1,2, Miku Inagaki1, 3, Ami Yamazaki1, Kennosuke
Itoh1, Kanako Miyano2,3, Miki Nonaka3, Yasuhito Uezono3, Hideaki Fujii1 (1Laboratory of Medicinal
Chemistry, School of Pharmacy, Kitasato University, 2Division of Cancer Pathophysiology, National
Cancer Center Research Institute, 3Department of Pain Control Research, The Jikei University Schoolof Medicine)

P-106

Combination study of partial structures in Phe-Tyr derivatives for antibacterial activity against
Stenotrophomonas maltophilia
Koushi Hidaka1, Yuko Tsuda2, Mizuki Sekiya3, Yasumitsu Sakamoto3, Saori Roppongi4, AkihikoNakamura5, Yoshiyuki Suzuki5, Wataru Ogasawara5, Nobutada Tanaka6 (1Graduate School of Health
Sciences, Kobe University, 2Faculty of Pharmaceutical Sciences, Kobe Gakuin University, 3School of
Pharmacy, Iwate Medical University, 4School of Medicine, Iwate Medical University, 5Department of
Science of Technology Innovation, Nagaoka University of Technology, 6School of Pharmacy, Kitasato
University)

P-107

Fluorescently labeled Heat-stable enterotoxin to detect cancer cells
Masaya Goto, Shinya Yoshino, Ryota Shinto, Koki Mizoe, Shigeru Shimamoto, Yuji Hidaka (Graduate
School of Science and Engineering Research, Kindai University)

P-108


ATR-FTIR study of synthetic peptide analogs of the calcium-binding site III of rabbit skeletalmuscle troponin C: Effects of amino-acid replacement
Masayuki Nara1, Hisayuki Morii1, Akira Sakamoto2, Takuya Miyakawa3, Masaru Tanokura3 (1Collegeof Liberal Arts and Sciences, Tokyo Medical and Dental University, 2College of Science andEngineering, Aoyama Gakuin University, 3Graduate School of Agricultural and Life Sciences,
University of Tokyo)
P-109

Preparation of cyclic peptide by the use of CPE peptide
Toru Kawakami, Eri Sasakura, Yohei Miyanoiri, Hironobu Hojo (Institute for Protein Research, Osaka
University)

P-110

Aqueous microwave-assisted solid phase peptide synthesis using Boc strategy II
Keiko Hojo1,2, Suzuko Fujiwara1, Hoshito Inai1, Yuki Manabe1, Koushi Hidaka3, Yuko Tsuda1,2(1Faculty of Pharmaceutical Sciences, Kobe Gakuin University, 2Cooperative Research Center of Life,
Kobe Gakuin University, 3Graduate School of Health Sciences, Kobe University)

P-111

Structural characterization of relaxin-like gonad-stimulating peptide from the starfish Astropecten
scoparius
Hidekazu Katayama1, Masatoshi Mita2 (1Tokai Univesrity, 2Showa University School of Medicine)

P-112

Total chemical synthesis of coronavirus-binding monobody through organopalladium chemistry
Eichi Ozawa, Gosuke Hayashi, Hiroshi Murakami (Nagoya University Gradute School go
Engineering)

P-113

Synthesis of a peptide-based drug carrier with endosome-disruptive activity
Shogo Hirota1, Takahito Imai 1, Masayuki Yamasaki2, Kin-ya Tomizaki1 (1Department of Materials
Chemistry, Ryukoku University, 2Department of Food Science and Human Nutrition, Ryukoku
University)

P-114

Synthesis of collagen model peptides with a phosphate group and a cell recognition site, andcharacterization
Garyu Hori, Kin-ya Tomizaki (Ryukoku University, Materials Chemistry)

P-115

Structural stability of collagen model peptides containing carboxyl groups
Naoki Takemura, Kin-ya Tomizaki (Ryukoku University, Materials Chemistry)

P-116

Selective gold ion reduction with an anthracene derivative
Shungo Teramura1, Masahiro Asano2, Kin-ya Tomizaki1 (1Department of Materials Chemistry,
Ryukoku University, 2Course of Environmental Ecological Engineering, Ryukoku University)

P-117

Synthesis of collagen model peptide with titanium and cell recognition sequences
Shun Tanaka, Kin-ya Tomizaki (Ryukoku University Graduate School)

P-118

Synthesis of analogs of a mitochondria targeting signal peptide from aldehyde dehydrogenase andeffects on cellular uptakes
Kei Takayama1, Masayuki Yamasaki2, Kin-ya Tomizaki1 (Department of Materials Chemistry,
Ryukoku University, 2Department of Food Science and Human Nutrition, Ryukoku University)

P-119

Synthesis of a mitochondrial targeting signal peptide and gold nanorods toward photothermal
therapy
Shoya Nakamura, Takahito Imai, Kin-ya Tomizaki (Ryukoku University Materials Chemistry)

P-120


Synthesis of nano-sized ribbon-shaped gold crystals using a peptide containing a nuclear
localization signal as a template
Kazutishi Ishida, Kin-ya Tomizaki (Ryukoku University)
P-121

Synthetic study of the selenocysteine-substituted epidermal growth factor
Toshiki Takei, Nobuaki Okumura, Hironobu Hojo, Toshifumi Takao (Institute for Protein Research,
Osaka University)

P-122

Almiramide peptide structure anti-leishmanial activity relationship
Anh Minh Thao Nguyen1, Noélie Douanne2,3, Claudia Duquette2,3, Audrey Corbeil2,3, Emanuella F.
Fajardo4, Martin Olivier4, Christopher Fernandez Prada2,3, William D. Lubell1 (1Department ofChemistry, Universite; de Montreal, Montreal, QC, 2Department of Pathology and Microbiology,
Faculty of Veterinary Medicine, Universite de Montreal, QC, 3The Research Group on Infectious
Diseases in Production Animals (GREMIP), Faculty of Veterinary Medicine, Universitde Montal,
4

P-123

Research Institute of the McGill University Health Center, Montréal, QC)

Synthetic strategies to unnatural prolines for constraining peptide backbone and side chain
geometry
Nassim Maarouf, Ramakotaiah Mulamreddy, William D. Lubell (Département de Chimie, Universitéde Montréal)

P-124

Peptidomimetic approach to allosteric modulators of the interleukin 1 receptor for delaying birthand improving neonatal outcomes
Charity D. Yongo-Luwawa1, Sylvain Chemtob2, William D. Lubell1 (1Department of Chemistry,
University of Montréal,

2

Departments of Pediatrics, Pharmacology and Physiology, andOphthalmology, University of Montréal)
P-125

Development of conformationally restricted negamycin derivatives for potent readthrough activity
Noriko Omura1, Akihiro Taguchi1, Keisuke Hamada1, Tomoki Kuwahara2, Mizuki Watanabe2,
Masanori Nakakuki3, Sho Konno1, Kentaro Takayama1, Atsuhiko Taniguchi1, Toshifumi Nomura4,5,
Satoshi Shuto2, Yoshio Hayashi1 (1Department of Medicinal Chemistry, Tokyo University of
Pharmacy and Life Sciences,
3

2

Faculty of Pharmaceutical Sciences, Hokkaido University,

Development Research, Mochida Pharmaceutical Co., Ltd., 4Department of Dermatology, Hokkaido

University Graduate School of Medicine, 5Department of Dermatology, Faculty of Medicine,
University of Tsukuba)