Health and Environmental Risk Division

Health and Environmental Risk Domain

The Health and Environmental Risk Division, one of six in the National Institute for Environmental Studies (NIES),

Research and studies for protecting human health andpreserving ecosystems from harmful factors in theenvironment, such as deleterious chemical contaminants

promotes several researches to protect human health and preserve ecosystems from environmental hazards, such as
chemical contaminants. The research includes the identification of hazardous factors; clarification of effectmechanisms, environmental fate, and exposure pathways; and development of testing, measurement, prediction,
environmental risk assessment and management methodologies.
National Institute for Environmental Studies
Audit Office

AuditorAdministration Department

Director

Planning Division
Research Collaboration Division

President

DeputyDirector

General Affairs Division

Environmental Exposure and Effect Research Section

contribute to the protection of human health andStrategic Risk Management Research Section

Foresight andAdvanced Basic
Research

the preservation of ecosystems from harmfulenvironmental factors, such as chemical

Health Effect Assessment Section

Earth System Division
Center for Global Environmental ResearchSatellite Observation Center
Material Cycles Division
Health and Environmental Risk Division
Regional Environment Conservation Division
Biodiversity Division
Social Systems Division
Center for Climate Change Adaptation
Fukushima Regional Collaborative
Research Center (FRECC)

Exposure Dynamics Research Section
Environmental Epidemiology Section
Research Office for Environmental Risk Science

Japan Environment and Children's Study Programme Office
Project Management Office

Lake Biwa Branch Office

Risk
Assessment

Integrated Health Risk Research Section

Environmental Exposure andEffect Research Section

Exposure
index

Exposure Dynamics Research Section

Ecotoxicity Research Section

Impactassessment

The foresight and advanced basic research includes

Policy-Oriented
Research

the following: (1) evaluation of the toxic effects of aIntellectual
Research
Infrastructure
Development

Group
analysis

Ecosystem Impact Research Section

variety of chemicals on organisms in theenvironment, from the molecular level to theCenter for Environmental Standards and Measurement
Environmental Standards Section
Environmental Measurement and Analysis Section

Environmental impacts
on human healthStrategic Risk Management
Research Section

contaminants.

Molecular Pathology Section

Research Department
Vice President

basic research and policy-oriented research toIntegrated Health Risk Research Section

Environmental Information Division

Organization

Ecotoxicity Research Section
Ecosystem Impact Research Section

Environmental impacts
on ecosystem

In this domain, we promote foresight and advanced

Health and Environmental Risk Division

PolicyOriented
Research

individual and population levels; (2) studies of
exposure to chemicals in the environment, andadvancement of methods for understanding andpredicting actual states of exposure;

Molecular Pathology Section
Health Effect Assessment Section
Environmental Epidemiology Section

Research Office forEnvironmental Risk Science

Center for
Environmental Standards Section
Environmental Standards
Environmental Measurement andand Measurement
Analysis Section

Related
Projects
Japan Environment
and Children's Study
Programme Office(3) development of new methods to assess theimpacts of ecosystem disturbance factors by using surveys, experiments, and model analysis; (4) systematization of chemical risk

The Division comprises nine sections, the Research Office for Environmental Risk Science, one center and one
program office. The sections are the Ecotoxicity Research Section, Environmental Exposure and Effect Research
Section, Ecosystem Impact Research Section, Strategic Risk Management Research Section, Integrated Health Risk
Research Section, Molecular Pathology Section, Health Effect Assessment Section, Exposure Dynamics Research
Section, and Environmental Epidemiology Section. Each section promotes research ranging from basic science toproject research such as strategic research programs. The Center for Environmental Standards and Measurement
has two laboratories – an Environmental Standards Section and an Environmental Measurement and Analysis
Section – which are responsible for fundamental work on environmental measurements, as well as for research anddevelopment. The Japan Environment and Children’s Study (JECS) Programme Office manages and coordinates
operations of this large-scale national project.

management and assessment of chemical kinetics and exposure; (5) development of methods for evaluating the health effects of
microplastics and environmental pollutants such as PM2.5, and elucidation of the effect mechanisms; (6) new health impact assessmentand mechanism elucidation considering multiple environmental factors, multiple diseases, and next-generation effects; (7) evaluation of
biological effects on the cranial nervous system and elucidation of mechanisms; (8) development of a biomarker-based method formeasuring lifetime exposure to pollutants; and (9) elucidation of the health effects of environmental pollutants and environmental
factors by using epidemiological methods and statistical analysis methods for epidemiological studies as a basis for JECS.
In our policy-oriented research, we promote regulatory science research that is based on the latest scientific findings, including theresults of our foresight and advanced basic research and our comprehensive environmental risk research program. We contribute toenvironmental policy through these results and promote our efforts as a reference laboratory.

Environmental Risk Research Laboratory

Micro-nanoparticle Research Laboratory

Animal Experimental Research Laboratory

Environmental Health Research Laboratory

AquatronThis is a comprehensive research facility thatplays a central role in research and studies
on environmental risks. It has experimental
facilities for a freshwater environment, aseawater environment, and chemical
analysis, and conducts research on
ecological impact
pact assessments, healthimpact assessments,
ments, and exposure
assessments.

In the Micro-nanoparticle ResearchLaboratory we investigate the physical andchemical properties of anthropogenic
aerosols, such as atmospherically-aged
aerosols and microplastics, from ultrafine
particles to micro-sized particles. We also
use inhalation chambers and exposure in
vitro to examine the health effects ofparticulate matter.

To clarify the effects of environmental
factors on human health, this researchlaboratory uses animal models andalternative methods, in compliance withethical guidelines for the use of animals, toconduct studies on the health hazards ofvarious environmental factors, including
chemical contaminants.

The Environmental Health ResearchLaboratory includes a variety of facilities
to evaluate pollution effects oncommunity health throughepidemiological studies on humans andexperimental studies on animals toevaluate the effects of environmental
pollutants.

The Aquatron is a research laboratory
consisting of thermostatic chambers, acontinuous flow through system, and an
aquarium to breed and culture various
aquatic organisms such as fishes andcrustaceans for use in ecotoxicity testing
and to distribute to other researchcompanies and institutes, universities, andschools.

Long-term Storage Facility of Environmental
Samples and Genetic Resources

Fundamental Instruments for Measurement
and Analysis/ Chemical Hazard Laboratories（Research buildings）

This Facility is for long-term storage ofenvironmental samples. To develop an
intellectual foundation for environmental
research, it plays a role in long-term
storage of biological samples, including
cells of endangered wildlife, andenvironmental samples, such asatmospheric dust.

The Fundamental Instruments for
Measurement and Analysis (FIMA) unit
facilitates general analysis within theinstitute. Chemical hazard laboratories,
which allow experiments with highly toxic
chemicals, such as dioxins, to be safely
used.

Research Facilities

12Sections and research office for basic and fundamental research
EEnvironmentali
t l iimpacts on ecosystemRisk
assessment

Environmental impacts on human healthStrategic Risk Management
Research Section

Impactassessment

Ecotoxicity Research Section
The Ecotoxicity Research Section isdeveloping ecotoxicity test methods andmodels to assess the ecological impact ofindividual chemicals and mixtures by using
techniques from molecular (e.g., genes andproteins) to organism levels (e.g., lethality,
growth, and reproduction).

We help to systematically manage the risks
to health and the environment by chemicals
and other risk factors. The study topics
include the occurrence and fate ofchemicals, emission and exposure modeling,
bioaccumulation, and the development andapplication of mathematical methods.
For example, we study
biogeochemical cycles of global
pollutants such as mercury (Hg) andestimate the Hg levels in seafood. We
also collect and statistically analyze
field data and develop mathematicalmodels to study the effects ofchemical substances on wildlife.

Exposure
index

Environmental Exposure andEffect Research Section

We use various organisms such as
fishes and invertebrates toinvestigate the adverse effects ofvarious chemicals, such as
endocrine-disrupting chemicals,pesticides, pharmaceuticals,surfactants, metals and microplastics, and their mixture; effluents; andambient water samples.

Group
analysis

Exposure
index

Ecosystem Impact Research Section
The Ecosystem Impact Research Section
elucidates the present status of exposure to
and adverse effects of environmental risk
factors in coastal ecosystems, the analysis ofmodes of action (mechanisms), andproposals for countermeasures to restore
the ecosystems. Environmental samples

have been collected in
the intertidal zone andcoastal waters of
Fukushima Prefecture
as well as Tokyo Bay,and analyzed bychemical, biological and histological techniques. Exposure experiments
are also conducted in the laboratory to identify causal factors.

Policyoriented
research

Integrated Health Risk
Research Section

Our research focuses on thedevelopment of methods formeasuring the properties ofatmospheric particulate matter ofnanometer to micrometer sizes, suchas microplastics and PM2.5, and thedevelopment of in vitro and in vivo
systems to evaluate the impacts ofatmospheric particulate matter on respiratory/cardiovascular organs
on present and future generations. We have also focused on
reproductive tissues, including germ cells, which atmosphericparticulate matter directly or indirectly affect. We search forbiological markers, such as the dynamics of germ cell organelles, by
taking advantage of genetic engineering and microscopic
technologies.

The Environmental Exposure and EffectResearch Section develops methods forunderstanding and predicting
environmental exposure to and effects ofchemical substances. To this end, we
conduct research on environmental
analysis of chemicals and air particles,
total toxicity assessments bybioassays, and process andproperty evaluation for new
environmental contaminants.
Our research is driven by
urgent social issues as well as
medium- to long-term
needs.

Risk
assessment

Exposure Dynamics Research Section
The research in this section focuses on
measuring and estimating lifetime exposures
to environmental stressors that may cause
adverse health effects in humans. These
environmental stressors include chemical
substances, the physical environment, anddiet, as well as socio-economic status andthe built environment. The totality of theenvironmental exposure is called theSocialEcosystems
exposome. The section is a leading
research group on the exposome in
Exposome
Japan. Human biomonitoring andexposure modelling are key tools in thisresearch. Imaging mass spectrometry is
PhysicalLifestyle
Chemicala flagship tool of this research section.

Research Office forEnvironmental Risk Science

The Research Office for Environmental Risk
Science provides domestic leadership for thepromotion of regulatory science based on
current scientific findings. The Office also aims
to implement environmental risk sciences
into environmental policies in Japan throughthe development and dissemination of
aquatic and avian ecotoxicological tests and the use of environmental
risk assessments. The Research Office consists of two teams. The
Environmental Risk Assessment Team conducts research on risk assessment
methods, and also works with government agencies to support scientificenvironmental risk assessment based on environmental laws. The
Ecotoxicity Reference Laboratory Team conducts research on ecotoxicity
testing methods using aquatic organisms. This team also co-operates
internationally to develop and standardize new testing methods.

3

Impactassessment

The Molecular Pathology Section provides
scientific knowledge that contributes tohealth risk assessments by evaluating theeffects of environmental factors such as
chemical contaminants on the onset andprogression of diseases and their molecularmechanisms.
We will evaluate the effects of environmental
factors (chemicals derived from consumer
products, air pollutants, etc.) on health andaging of the present and future generations,and elucidate the molecular mechanisms ofthese effects. We will analyze not only target
organ toxicity but also interactions of biological systems (immune
system, metabolic/endocrine system, brain and nervous system, etc.).

Impactassessment

Health Effect Assessment Section

We contribute to the prevention andreduction of adverse effects fromenvironmental pollutants and otherenvironmental factors on health bydeveloping methods to evaluate theireffects on the brain and nervous system,and other systems. We aim to develop asensitive evaluation methodby analyzing at various levels,
including the molecular,
cellular (embryonic stem cells,
primary cell culture),tissue/individual, andbehavioral levels, as well as byusing fragile animal models.

Group
analysis

The above Sections in the Health and Environmental Risk Division promote basic andfundamental research and policy-oriented research to reduce the environmental risks tohuman health and ecosystems associated with harmful environmental factors such as
chemical contaminants. We aim to contribute to the management of chemicals andenvironmental health policies through our policy-oriented research. Our basic andfundamental research includes the identification of toxic factors; their effects on sensitive
biological receptors and health risks; chemical kinetics and exposure pathways; thedevelopment of testing, measurement and prediction methods; and environmental
biophysical and epidemiological studies. In policy-oriented research, we promote regulatory
science research based on the latest scientific findings, risk assessment projects, chemical
substance database operations, and the distribution of experimental aquatic organisms.

Molecular Pathology Section

Environmental Epidemiology Section

The Environmental Epidemiology Section
conducts epidemiological surveys andother research to clarify the effects ofenvironmental pollutants andenvironmental factors on health andprovides knowledge that contributes tohealth impact assessments and healthhazard prevention policies. We are also developing and upgrading
epidemiological research methods. Specifically, in addition topromoting JECS, we are investigating the relationship between
exposure to air pollution and health effects, the critical period of
health-promoting factors in life-course epidemiology, and theinteraction between humans and animals, and epidemiologicallystudying global health related to food and health in developing
countries.

4Comprehensive Environmental Risk Research Program
Research Program on Comprehensive Assessment and Managementof Human and Ecological Health Risk Caused by Chemicals and Other Pollutomes.
In this program, we are conducting research to promote the comprehensive risk assessment and management of chemicals and the total of all forms of pollution that can harm human and ecological health (i.e., the pollutome). To assess and manage the greaterpart of chemicals originating from human activities, we expanded the target chemicals to all chemicals of concern and considered vulnerable groups and life stages of humans and other organisms. In addition, we upgraded our comprehensive measurements andmathematical models to better assess those effects and risks that have been hard to quantify. As a result of these efforts, we are helping to establish comprehensive health risk indexes and ecological risk indexes.

Brain &
nervoussystemImmunesystemEnvironmental factors

Chemicals

Health Hazards Project
Health hazard assessment considering
the real-life environment andvulnerabilities

Metabolic/endocrine
systemReproducƟve
systemHealth hazard assessment of chemicals
with endpoints of effects on health(immune diseases, metabolic diseases,
neurodevelopmental disorders, etc.),
reproduction, and future generations.

Pollutome Measurement Project
Comprehensive pollutome measurement
This project develops methods to measure and understandexposure to all environmental chemical substances of concern. We

The health effects of chemicals vary with exposure level and sensitivity,
but their effects in the real world are not fully understood. The Health
Hazards Project will conduct systematic research on the health effects
of environmental factors, including chemicals, over the lifetimes ofpresent and future generations. We will evaluate the health hazards,

Comprehensive Risk Indexes
Projectmechanism-based impact indicators, and propose new evaluation andDevelopment of comprehensive health risk
and ecological risk indexes

prediction methods. These contributions will facilitate theThis project proposes and develops comprehensive health risk anddevelopment of comprehensive health risk indexes.

ecological risk indexes considering factors not currently involved inconsidering the real-life environment and vulnerabilities, findwill also develop new methods of analyzing chemical substancesthat have been hard to identify and quantify, as well as establish ascheme that will facilitate identification of causative factors when
new effects become apparent. To efficiently search forcontributors to bioactivity, we will also develop selective collection
materials and data analysis methods for substances that sharecommon structures.

Triple quadrupole mass spectrometers,
high-resolution mass spectrometers,
microflow systems, etc. are used todevelop comprehensive measurement
methods for organic pollutants.

quantitative risk assessment schemes. The factors include toxic
effects that are difficult to assess quantitatively, consideration of

PJ2

Ecological Hazards Project
Environmental surveys along the coast of
Fukushima Prefecture, Japan. Fisheriesindependent bottom-trawl surveys andenvironmental monitoring since October 2012
include nine sites at 10-, 20-, and 30-m water
depths. Spatiotemporal patterns in the
megabenthic community along the Fukushimacoast after the 2011 earthquake, tsunami, andnuclear disaster have been investigated.

Potentially
Affected Fraction

x
x
x
x

Ecological hazards and factor analysis
considering vulnerabilities

vulnerable populations, environmental fate of chemical mixturesand degraded products, and grouping of similar substances.
Scientific information and findings from the four other PJ projects
are being assembled, and comprehensive risk indexes will be
proposed. The outcome of the project is contributing to both
domestic and international environmental policies.

chemicals and other pollution factors, but their causal analysis has
been insufficient. To understand the factors that cause suchimpacts and evaluate control measures, we collaborate on field

investigate ecological hazards. Comprehensive ecological risk
indexes are also developed to assess the combined effects ofvarious factors.

xx Example of Species
Sensitivity Distribution (SSD)x

We are developing and improving methods to derive emission

Approaches bycomprehensive
hazard indicators

Comprehensive
indicators

Developmentof comprehensive
risk indexes

Number of chemicals
simultaneously assessed

surveys of biota, laboratory experiments, and mathematicalmodels. By focusing on vulnerable species and life stages, we

Modeling the environmental fateof the pollutome

H
Hazardassessment index

There have been many studies on the ecological impacts ofSingleSimilarChemicals

Current regulatory
scheme ofrisk assessment

Environmental Fate Project

Structure SameAll chemicals
class
application of concern
purposeApproaches bygrouping of chemicals

inventories, physicochemical parameters, bioaccumulation
properties, and multimedia models to evaluate the environmental
fate of all substances of concern for which we have only limited
risk evaluation information; these methods will contribute toexposure assessments. These methods include a novel emission
estimation method, focusing on substances categorized into theionic organic substances.
Simulated concentrations of a pollutant in
the atmosphere by a global environmental
model FATE (upper map) and simulated
concentrations of a pollutant in river waterby a regional model G-CIEMS (lower map)

Conceptual diagram of comprehensive assessmentsof health and ecological risks.

Assessment of ecological impacts of a chemical
on vulnerable species by investigating thespecies sensitivity distribution.
5

G-CIEMSsame usage, and bioaccumulation models applicable to polar andIndividual endpoints

Concentration of a Chemical

FATE

6

Center for Environmental Standards and Measurement

Japan Environment and Children's Study Programme Office

Research and development on environmental reference materials andon methods to improve the accuracy of chemical measurements

Provides core administrative and technical support for the conduct of
the Japan Environment and Children’s Study (JECS).

To understand the environment surrounding us, identify problems as quickly as possible, and respond appropriately, it is important to observeJECS is a nationwide birth cohort study funded by the Ministry of the Environment. It aims to identify environmental factors that affect the healthand measure the environment. It is also important to continue to observe and measure the environment to determine the progress ofand development of children. The Programme Office in NIES manages the study in collaboration with the National Center for Child Health andenvironmental problems and the effectiveness of countermeasures. The Center for Environmental Standards and Measurement provides

Development, which serves as the Medical Support Centre and provides the Programme Office with medical expertise, as well as with 15 Regional

high-quality technology and data for environmental measurement and contributes to solving environmental problems and improving theCentres based at universities and research institutes throughout Japan.

environment by ensuring its reliability as a national research institute. In order to maintain and improve measurement accuracy, we develop
environmental reference materials and apply observation, measurement, and analysis methods. This center is also actively engaged in basic
Recruitment of pregnant women to the study began in 2011;

research to clarify phenomena and principles.

■ Study Locations ■by the end of 2014, more than 100,000 mother–child pairs
In this Center, the Environmental Standards Section and the Environmental

Medical Support Centre

for collecting data, starting from pregnancy and following

Measurement and Analysis Section are responsible for fundamental

the children over the long term. In the main study, biannual

measurement work in an inter-disciplinary manner, as well as advanced

participants, such as their health and development, and theperforming requested chemical analyses using instruments, the laboratory

Kanagawa

measurements, and psycho-developmental tests; pediatricenvironment, we are also promoting a long-term preservation project for

Aichi

examinations more thoroughly investigate the impact ofenvironmental samples, including collection, long-term preservation, andStorage of environmental samples in liquid nitrogen tanks

Chiba

Fukuokameasurement methods such as home visits, ambient air

increase their utility. In addition, to understand the status of chemicals in the

Fukushima
Programme Office

Tottoriselected from the main cohort, and more in-depth

values and reference values to existing environmental reference materials to

MiyagiHyogo

A sub-cohort study involves 5000 children randomlyinternational standards in response to social needs. We also add certified

ToyamaKyoto

environmental factors to which they are exposed.

also prepares and provides environmental reference materials that meet

KoshinProgramme Office
Medical Support Centre
Regional Centre

questionnaires are used to collect information on themeasurement research in cooperation with other fields. In addition to

analysis of bivalve mollusks from the coast of Japan.

Hokkaido

had been registered. The Regional Centres are responsible

Osaka
Kochi

environmental factors on outcome variables.

South Kyushu/Okinawa

The Programme Office develops standard operation
Environmental
Reference
Materials

Environmental Standards Section

Environmental
Measurement

We are contributing to the realization ofquality control by producing and distributing
certified reference materials. Environmental
samples are systematically collected,
homogenized, and stored for long periods
for future chemical analysis.

Environmental Measurement andAnalysis Section
We believe that producing primary data
through original experiments and observations
is one of our advantages. We provide
high-quality environmental measurement data
and develop and apply observation,measurement, and analysis methods tomaintain and improve measurement accuracy.

We present scientific methods anddirections for monitoring environmental
pollutants, which are regulated
internationally in line with environmental
policies. We are also developing andapplying rapid sampling methods toestimate the effects of chemicals leaked
during disasters.

We are also actively engaged ininnovative studies, such asmeasurement-based research toaddress future environmental
issues and the development ofadvanced environmental
measurement methods tofacilitate scientific breakthroughs.

7

procedures, centralizes the data collected by the Regional
Centres, administers the data management system,
maintains the repository of biological and environmental
samples, and performs exposure measurements; it is also
responsible for risk management and participant retention.
In addition, the Programme Office takes a leadership role infacilitating collaboration among the domestic andinternational research groups involved in the environmental
birth-cohort study and provides a platform for the efficientexchange of information among the various researchgroups involved.

Storage of biospecimens collected as part of JECS.

Japan Environment andChildren’s Studyin Japanese

8

https://www.nies.go.jp/jecs/index.html

Databases and websites managed by Health and Environmental Risk Division
KAshinhou Tool for Ecotoxicity (KATE)
https://kate.nies.go.jp/index-e.html

Prediction tool of a chemical’s aquatic toxicity to fish, daphnid, and algae
KATE is a web application tool that predicts ecotoxicity values to aquatic organisms (fish, water flea (Daphnia magna) and algae) according to“OECD Test Guidelines for Chemicals.” The tool is based on quantitative structure-activity relationship (QSAR) models and predicts both acute andchronic ecotoxicity values.

Collection of reference materials for the establishment of Environmental Quality Standards
https://www.nies.go.jp/eqsbasis/index.html

What are the bases for establishing environmental quality standards in Japan?
The environmental quality standards (EQSs) for air, water, soil, and noise have been established and revised by the Ministry of the Environment, Governmentof Japan. This website collects references regarding the establishment and revision of EQSs and related items such as guideline values. The documents,
references, and main texts on this website are written in Japanese, but summaries for each environmental medium will be translated into English.

Chemical Substance Database (Webkis-Plus)
https://www.nies.go.jp/kisplus/(in Japanese)

Get comprehensive information on chemical substances by extensive search functions
Webkis-Plus is a website providing comprehensive information relating to environmental risk management. This site contains information on
physicochemical properties; regulations (related mainly to environmental pollution); environmental concentrations from surveys; volumes ofsubstances manufactured, imported, or both; volumes of agricultural chemicals shipped to each prefecture; Pollutant Release and Transfer Register(PRTR) emissions and transportation amounts; risk assessment results; and so on.

Grid-Catchment Integrated Environmental Modeling System (G-CIEMS)
https://www.nies.go.jp/rcer_expoass/gciems/gciems.html(in Japanese)

Simulates the environmental fate of contaminants throughout Japan
G-CIEMS is a spatially resolved and geo-referenced, dynamic, multimedia environmental fate model. This model predicts the concentrations ofchemicals in the atmosphere, surface waters, surface water sediments, surface soils, coastal waters, and sewage collection areas based on
environmental emissions and physicochemical properties of the target substances and use of geographical and meteorological information.

National Institute for Environmental Studies

Health and Environmental Risk Division

Simulation Models and Tools for Exposure Assessment
https://www.nies.go.jp/rcer_expoass/index.html(in Japanese)

Get models and tools for simulating environmental fates and visualizing geographic data
This website provides the following models and tools: G-CIEMS; the Multimedia Simplebox-systems Environmental Model (MuSEM), which is an
integrated tool for assessing environmental risk; and a tool for visualizing geographic data containing simulation results obtained by G-CIEMS, andso on.

Tools for GC(×GC)-MS

https://www.nies.go.jp/risk_health/analysis/gcgcms.html(in Japanese & English)

A collection of programs designed for accurate mass spectrometry data analysis (for researchers)
This page provides original software to analyze data from a gas chromatograph-mass spectrometer (GC-MS) or a comprehensive two-dimensional
gas chromatograph (GC×GC)-MS. A GC×GC is an instrument that can separate dozens of times more components than a conventional GC, allowing
simultaneous separation of many kinds of chemicals. In addition, the high-resolution time-of-flight mass spectrometer (HRToFMS) is capable ofextremely fast, accurate mass analysis. The combination of these instruments contributes to research on environmental pollution caused by a wideand complex variety of chemicals.

Tsukuba Air Quality Monitoring Data
https://www.nies.go.jp/aqrs/index.html(in Japanese)

Real-time PM2.5 and other air quality concentrations are reported.
As a part of quality control of the measurements, continuous air quality monitoring has been conducted at the Atmospheric Measurement andExperiment Laboratory (Air Quality Research Station) of NIES since 1978. The measurement results since 1995 are available on our website, and moredetailed information and data can be provided upon request.

The fifth five-year plan（2021-2025）
Health and Environmental Risk Division

2022.12National Institute for Environmental Studies

Health and Environmental Risk Division
Address : 16-2 Onogawa, Tsukuba, Ibaraki 305-8506 JAPANURL: https://www.nies.go.jp/risk_health/index-e.html
This publication is printed on paper manufactured entirely from recycled material (Rank A),
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The fifth five-year plan（2021-2025）