2023 Final Priorities Groupings for New Reports
2023 Reports – per cause

HC Blue No. 15 – proposed PCPC Hair Color Technical Committee(HCTC)

FOU = 22

Reported Function: Hair ColorantNotes: Since FOU might not be a very accurate surrogate for exposure, with regard to hair dyes, the PCPCHCTC proposes one hair dye ingredient annually for Panel review. The HCTC typically submits a proposed
hair dye ingredient between the 1st and 2nd meetings of the year.
Grouping: None

Prostaglandins analogs – e.g., Isopropyl Cloprostenate

FOU = 3– Alert from Dr. Belsito about SCCS activity; conformation from FDA about cosmetic use

Reported Functions: Hair Conditioning Agents; Eyelash Conditioning Agents; Nail Conditioning Agents;
Antimicrobial Agents; Antioxidants; Skin-Conditioning Agents - Miscellaneous
Notes: These are prostaglandin analogs that might be in use as cosmetic ingredients, despite morecommon usage as drugs.
Grouping: (2 ingredients proposed with a total FOU = 3)
Isopropyl Cloprostenate
Ethyl Tafluprostamide

FOU3-1|Page2023 Reports – per FOU

Sodium Hydrosulfite

FOU = 246

Definition: Sodium Hydrosulfite is the inorganic salt that conforms to the formula Na2S2O4.

Reported Function: Reducing Agents
Grouping: None

Pelargonium Graveolens Flower Oil

FOU = 236

Definition: Pelargonium Graveolens Flower Oil is the volatile oil obtained from the flowers of Pelargonium
graveolens.

Reported Functions: Fragrance Ingredients; Skin-Conditioning Agents - Miscellaneous
Notes: (CAS Nos. 90082-51-2 (generic) and 8000-46-2) Pelargonium Graveolens Oil (FOU 179),
Pelargonium Graveolens Leaf Oil (FOU 13), and Pelargonium Graveolens Flower/Leaf/Stem Water (FOU9) are fragrance only ingredients.
Grouping: (5 ingredients proposed with a total FOU = 294)
Pelargonium Graveolens Flower Oil
Pelargonium Graveolens Extract
Pelargonium Graveolens Flower Water
Pelargonium Graveolens Flower Extract
Pelargonium Graveolens Leaf Extract (VCRP name only)

FOU
236
49
4322|Page

Phytosteryl/Isostearyl/Cetyl/Stearyl/Behenyl
Dimer Dilinoleate

FOU = 234

Definition: Phytosteryl/Isostearyl/Cetyl/Stearyl/Behenyl Dimer Dilinoleate is the ester of Dilinoleic Acidwith a mixture of Phytosterols, Isostearyl Alcohol, Cetyl Alcohol, Stearyl Alcohol, and Behenyl Alcohol.

wherein the carboxylic acid functional groups are esterified with Phytosteryl, Isostearyl, Cetyl, Stearyl,and/or Behenyl chains.
Reported Functions: Hair Conditioning Agents; Skin-Conditioning Agents - Occlusive; Viscosity Increasing
Agents – Nonaqueous
Notes: Final Amended Safety Assessment of Dialkyl Dimer Dilinoleates as Used in Cosmetics finalized in2018 with a safe as used conclusion for all 8 ingredients therein. Final assessment on Diisostearoyl
Polyglyceryl-3 Dimer Dilinoleate finalized in 2016 with a safe when formulated to be non-irritatingconclusion.
Grouping: (7 ingredients proposed with a total FOU = 398)
Phytosteryl/Isostearyl/Cetyl/Stearyl/Behenyl Dimer Dilinoleate
Bis-Behenyl/Isostearyl/Phytosteryl Dimer Dilinoleyl Dimer Dilinoleate
Stearyl/PPG-3 Myristyl Ether Dimer Dilinoleate
Dimer Dilinoleyl Dimer Dilinoleate
Bis-Behenyl/Phytosteryl Dimer Dilinoleate
Phytosteryl Isostearyl Dimer Dilinoleate
Octyldodecyl/PPG-3 Myristyl Ether Dimer Dilinoleate

FOU234823323
196
13|PageDiglycerin & Polyglycerin-3

FOU = 211
FOU = 208

Definition: Diglycerin is a dimer of Glycerin. Dimerization (and resultant connectivity) can occur at any of the alcoholgroups (although less substituted alcohols are energetically favored (i.e., primary > secondary >> tertiary).
OHHOOH

OOH

Reported Functions: Humectants; Skin-Conditioning Agents - Humectant
Notes: (CAS No. 59113-36-9) Polyglycerin-3 is essentially “triglycerin.”
Grouping: (4 ingredients proposed with a total FOU = 451)
Diglycerin
Polyglycerin-3
Polyglycerin-10
Polyglycerin-6

FOU
211
208
29
3

Sigesbeckia Orientalis Extract

FOU = 202

Definition: Sigesbeckia Orientalis Extract is the extract of Sigesbeckia orientalis.

Reported Functions: Skin-Conditioning Agents - Miscellaneous
Notes: VCRP name is “Sigesbeckia Orientalis (Eastern St. Paul's Wort) Extract”
Grouping: None4|PageHouttuynia Cordata Extract

FOU = 201

Definition: Houttuynia Cordata Extract is the extract of the herb, Houttuynia cordata.

Reported Functions: Skin-Conditioning Agents - Miscellaneous
Notes: (CAS No. 164288-50-0)Grouping: (2 ingredients proposed with a total FOU = 203)
Houttuynia Cordata Extract
Houttuynia Cordata Powder

Malva Sylvestris (Mallow) Extract

FOU201
2FOU = 198

Definition: Malva Sylvestris (Mallow) Extract is the extract of the whole plant, Malva sylvestris.

Reported Functions: Skin-Conditioning Agents - Miscellaneous
Notes: Related to Althaea officinalis or marshmallow.
Grouping: (8 ingredients proposed with a total FOU = 287)
Malva Sylvestris (Mallow) Extract
Malva Sylvestris (Mallow) Flower Extract
Malva Sylvestris (Mallow) Flower/Leaf/Stem Extract
Malva Sylvestris (Mallow) Flower/Leaf Extract
Malva Sylvestris (Mallow) Leaf Extract
Malva Sylvestris (Mallow) Oil (VCRP name only)
Malva Sylvestris (Mallow) Leaf Powder
Malva Sylvestris (Mallow) Flower

FOU198725442115|Page

Palmitoyl Pentapeptide-4

FOU = 198

Definition: Palmitoyl Pentapeptide-4 is the reaction product of palmitic acid and Pentapeptide-4. Pentapeptide-4 isa synthetic peptide containing lysine, serine and threonine (PAL-LYS-THR-THR-LYS-SER).

Reported Functions: Skin-Conditioning Agents - MiscellaneousNotes: (CAS Nos. 214047-00-4 & 521091-64-5) the 3 proposed ingredients all share the same peptide
sequence
Grouping: (3 ingredients proposed with a total FOU = 202)
Palmitoyl Pentapeptide-4
Pentapeptide-4
Myristoyl Pentapeptide-4

Salix Alba (Willow) Bark Extract

FOU198
13FOU = 197

Definition: Salix Alba (Willow) Bark Extract is the extract of the bark of Salix alba.

Reported Functions: Hair Conditioning Agents; Skin-Conditioning Agents - Occlusive
Notes: (CAS No. 84082-82-6) Willow tree
Grouping: (2 ingredients proposed with a total FOU = 238)
Salix Alba (Willow) Bark Extract
Salix Alba (Willow) Leaf Extract

FOU
197
416|Page

Centaurea Cyanus Flower Extract

FOU = 196

Definition: Centaurea Cyanus Flower Extract is the extract of the flowers of the cornflower, Centaurea cyanus.

Reported Functions: Cosmetic Astringents; Skin-Conditioning Agents - Miscellaneous
Notes: (CAS No. 84012-18-0) “Cornflower”
Grouping: (3 ingredients proposed with a total FOU = 265)
Centaurea Cyanus Flower Extract
Centaurea Cyanus Flower Water
Centaurea Cyanus Flower Petals (VCRP name only)

Lactobacillus Ferment

FOU
196
68
1

FOU = 196

Definition: Lactobacillus Ferment is the product obtained through fermentation by the microorganism, Lactobacillus.

Reported Functions: Not Reported
Notes: (CAS No. 2380025-37-4 (generic)) Probiotics?
Grouping: (4 ingredients proposed with a total FOU = 213)
Lactobacillus Ferment
Lactobacillus Ferment Lysate
Lactobacillus Ferment Lysate Filtrate
Lactobacillus Ferment Filtrate

Copper Gluconate

FOU196863

FOU = 192

Definition: Copper Gluconate is the copper salt of gluconic acid that conforms to the formula:

Reported Function: Skin-Conditioning Agents – Miscellaneous
Notes: (CAS No. 527-09-3)
Grouping: None

7|PageInositol

FOU = 190

Definition: Inositol is the cyclic polyol that conforms generally to the formula:

Reported Function: Hair Conditioning Agents; Humectants
Notes: (CAS Nos. 643-12-9 & 87-89-8)
Grouping: None

Paeonia Suffruticosa Root Extract

FOU = 189

Definition: Paeonia Suffruticosa Root Extract is the extract of the roots of Paeonia suffruticosa.

Reported Functions: Skin-Conditioning Agents - Miscellaneous
Notes: (CAS No. 223747-88-4 (generic))
Grouping: (5 ingredients proposed with a total FOU = 216)
Paeonia Suffruticosa Root Extract
Paeonia Suffruticosa Extract
Paeonia Suffruticosa Bark Extract
Paeonia Suffruticosa Seed Oil
Paeonia Suffruticosa (Tree Peony) Root Bark Extract (VCRP name only)

FOU189137528|PageNelumbo Nucifera Flower Extract

FOU = 182

Definition: Nelumbo Nucifera Flower Extract is the extract of the flower of Nelumbo nucifera.

Reported Functions: Skin-Conditioning Agents - Miscellaneous
Notes: (CAS No. 85085-51-4 (generic)) “Lotus”
Grouping: (13 ingredients proposed with a total FOU = 285)
Nelumbo Nucifera Flower Extract
Nelumbo Nucifera Seed Extract
Nelumbo Nucifera Leaf Extract
Nelumbo Nucifera Root Extract
Nelumbo Nucifera Flower Water
Nelumbo Nucifera Flower Oil (VCRP name only)
Nelumbo Nucifera Callus Culture Extract
Nelumbo Nucifera Germ Extract
Nelumbo Nucifera Extract
Nelumbo Nucifera Stamen Extract
Nelumbo Nucifera Flower/Leaf/Stem Juice
Nelumbo Nucifera Seed Powder
Nelumbo Nucifera Root Water

FOU
182
26171614978211119|Page