長崎大学医学部業績集 2.研究業績

原爆後障害医療研究施設分子医療部門分子診断研究分野
At0π'C Bomb D娩磁 1鵬ti加te MoleC址ar MediC血e unit, D叩artment of Nat11te Me'ichle

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1. K. Akino, A. oh橋Uru, M. Nakashima, M.1to, Y. Ting‑Ting, T. Kawawaki, J Baba, S. Yamashita, N IW且hori:

Distribution ofthe parathyroid hormone‑related peptide and its receptor in the saccus vasculosus and choroid
Plexus in the Ted stingray (Dasyatis akajei: Elasmobranch). ce11 MOI Neurobi01 18,361‑368 a998)*
2. S. Nagataki, K. AshizaWヨ, S. Ya訂la5hita: C且Use of childhood thyroid cancer 且tter the chernobyl accident‑Thyroid 8,115‑117 a"8)、
3. T. Har且, H. N且mb且, T.T. Y且ng, Y. N且g且y且m且, K. Kuma, N.1Shik且、va, K.1to, S. Yamashita:10nizingradiation
activates c‑Jun NH2‑terminal kinase σNK/SAPK)via a pKC‑dependent pa血Way in human thyroid ce11S.
Biophys Biochem Res commUΠ 2",41‑U (1998)* 0
4. K. Tanaka, Y. Nagayama, T. Nak且no, N. Tak且mura, H. Namba,S. Fukada, K. Kum且, S. Yam日Shit且, M. Niwa:Expression profile of receptor‑type protein tyrosine kinase genes ln the human thyroid. Endocrin010gy ]39,3,852‑858 (1998)、

5. S. Yamash辻a: Endocrine Disease and APOP加Sis.1ntern Med 37,2,194‑196 (1998)
6. K. Ashizawa, T. Krupnik, S. Nag且t且ki, S. Yamashita: Tr且nsient Thyrotoxicosis aTound chernobyl. Thyミ0id
8,6,535‑536 (1998)、

フ. E. Nishihar日, Y. N日g且yama, M. NaTimatsu, H. Namb且, M. wat且n且be, M. N武Va, S. Yamashita: Treatment ofthyroid cardnoma ce11S wlth four different suicide gene/prodTug combin且tions in vitTO. AntiC且ncer ReS 18,1521‑ 1526 (1998)・
8. T. Motomura, Y.E. Nikiforov, H. Namba, K. AshizaW且, S. Nag且t且ki, S. Yamashita, J.A. Fagln: RetTearrange・

ments in Japanese pedltric and 且dult P且PiⅡ且ry thyroid cance玲. Thyroid 8,6,蝿5‑4釣住的8)*
9. N. Takamura, S. Yamashita, H. Namba, G. Alipov, M.1to,1, sekine, M. Espenhetova, B. Gusev: Need forinvestigation of thyroid dise且Se around semipalatinsk nuclear testing site, Kazakhstan. T11yroid 8,フ,635‑636(1998)、

10.0.Fof且noV且, N. Takamura, E. Kinoshita, M. Yoshimoto, Y, Tsuji, V,A. peterokova,0.V. Evgafov,1.1. Dedov,N.P. Goncharov, S. Yam且Shit2: R且rity of plTlinvolvement ln chⅡdren fTom RU鵠ia with combined pituitaryhormone deficiency. Am J Med GeneticS 7フ,360‑3儒(1998)*
11. Y. Cヨ0, T. M且tsumoto, K. Motomuta, A. ohtsuru, S. Yamashita, M. Kosaka:1mpaired induction ofhe日t chockProteln implicated in decreased thermot010erance in a tempoaTatute‑se力Sitive multinudeated ceⅡ line.
Pflugers ATch Europ J physi01 437,15‑20 (1998)、
12.0. Fofanova, N. Takamura, E, Kinoshita, J,S. patks, M.R, Brown, V.A, peterkova,0.V. Evgrafov, N.P.
Gonchar0ν, A, A. Bulatov,1.1. Dedov, S. Y2mashita: A mutation且l hot spot in the prop‑1 gene in Russi且nChildren 工Vith combined pituit且ry hormone deficiency. pituitary l,45一四(1998)
13.0. Fofanova, N. Takamura, E. Kinoshita, J.S. parks, M. Brown, V. peterkova,0. Evgrafov, N. Goncharov, A.
Bulatov,1.1. Dedov, S. Yam且Shita: compound heterozygous deletion of the prop‑1 gene in children with

Combined pituitary hormone deficiency. J clin Endocrine Metab 鉛,フ,2601‑2604 (1998)*

14. V, Btaiden, Y, Nagay且ma, M.1it且ka, H. N且mb且, M. NiW且, S. Y且m且Shita: Retrovirus‑mediated suicide gene/Prodrug theτ且Py 捻rgeting thyroid carcinoma using a thyroid‑specific promoter. Endocrin010gy 139,9,3996‑3999 a998)、

15. T.1Sukazaki, T. chi且n, A. Davison, L. A廿iS且no, J.L. W'r且na: SARA,且 FYVE dofnain protein that tectuits
Sm且d 2 to the TGFB receP加r, ce11 96,6,フ79‑791 (1998)*
16. Y. shirahlge, M.1to, K. AshlzaW且, T. Nishikawa, N. Yokoyama, H. Namba, N.1Shikawa, T. Mimura, S.
Fukata, T. Yokozawa, S. Yam且Shita: ch且r且Cteristic features ofchildhood thyroid canceriヨ Japan and Belarus.

Endocrine J 45,203‑2佃 a998)、
17. H. Yoshimoto, H. Yano, K. Kob且yashi, A. HiTano, K. Motomur且, A. ohtsuru, S. Yamashita, T. Fuj":1nce且Sed
Prolifer且tive 且C6Vity of osteoblasts in congenit且l hemifacialhypertrophy. plastic and RecoDstructive suTgery
102,5,16妬一16]0 (]99幻*18. M. Nari1Πatsu, Y. Nagayama, K. Aklno, M. Y且Sud且, T. Y且m且moto, T.T. Yang, A. ohtsuru, H. Namba, S.
Y且mashita, H. Ay日be, M. N武Va; Therapeutic usefulness of WⅡd‑type P53 gene introduction in 且 P53‑nUⅡ
anaplastic thyroid carcinoma ceⅡ line. J clin Endocrinol Metab 83,10,3668‑3672 a998)*
19. S. Ya訂lashita, Ed此orial: sporadic multiple endocrine neoP1日Si且 type 2A.1ntern Med 37,12 a998)*‑49‑