1st International Symposium on Flow Science and Technology(ISFST-1)
Monday, March 7, 2022 - Tuesday, March 8, 2022

Program■ Monday, March 7, 2022
13:10 - Opening Remarks
Shū Kobayashi (The University of Tokyo, National Institute of Advanced
Industrial Science and Technology (AIST))
13:20 - Invited lecture (IL-1)“One-flow, Short Step Sequential Continuous-flow Synthesis of Valuable
Small Molecules with Heterogeneous Catalysts”
Haruro Ishitani (The University of Tokyo)
14:00 - Oral presentation (OP-01)“Second Generation Phenolsulfonic Acid-Formaldehyde Resin Catalyst(PAFR II) for Continuous Flow Esterification of Carboxylic Acids andAlcohols”
Yoichi M. A. Yamada (RIKEN Center for Sustainable Resource Science)
14:20 - Oral presentation (OP-02)“Continuous–Flow Reactions over Highly Durable Heterogeneous Catalysts”○Koichiro Masuda,1 Rashed Nurnobi,1 Shū Kobayashi,1,2 and Kazuhiko Sato1(1National Institute of Advanced Industrial Science and Technology (AIST), 2The
University of Tokyo)
14:40 - Oral presentation (OP-03)“Development of Heterogeneous Metal Nanoparticle Catalysts forContinuous Flow Synthesis of Chiral Molecules”○Tomohiro Yasukawai,1 Shū Kobayashi1,2 (1The University of Tokyo, 2National
Institute of Advanced Industrial Science and Technology (AIST))
15:00 - Break15:20 - Invited lecture (IL-2)
Aaron B. Beeler
16:00 - Oral presentation (OP-04)“Development of continuous-flow hydrogenation methods of nitriles intotertiary, secondary, and primary amine”
Kwihwan Kobayashi, Tsuyoshi Yamada, Hironao Sajiki (Gifu PharmaceuticalUniversity)
16:20 - Oral presentation (OP-05)“A Novel and Versatile Immobilization Method of Chiral Metal
Catalysts Utilizing Non-covalent Interactions for ContinuousFlow Enantioselective Catalysis”○Yuki Saito,1 Shū Kobayashi2 (1 The University of Tokyo) （2National Institute ofAdvanced Industrial Science and Technology (AIST)

16:40 - Exhibition and poster session
18:20

End

■ Tuesday, March 8, 2022
10:30 - Invited lecture (IL-3)“API Continuous Cooling and Antisolvent Crystallization for Kinetic
Impurity Rejection in cGMP Manufacturing”○Martin D. Johnson,1 Christopher L. Burcham,1 Scott A. May,1 Joel R. Calvin,1Jennifer McClary Groh,1 Steven S Myers,1 Luke P. Webster,1 Jeffrey C. Roberts,1Carla V. Luciani,1 Aoife P. Corrigan,2 Richard D. Spencer,2 Robert Moylan,2Raymond Boyse,2 John D. Murphy,2 James R. Stout3 (1Eli Lilly and Company,
2Eli Lilly Kinsale, 3D&M Continuous Solutions)
11:10 - Oral presentation (OP-06)“Proposal for Energy Efficient Strategy toward Carbon Recycle Society:Aerobic Oxidations of Alkanes in Flow”

Tetsuo Nakajo (National Institute of Advanced Industrial Science andTechnology (AIST))
11:30 - Oral presentation (OP-07)“Roadmap for Practical Use of Continuous Manufacturing SystemiFactory® by 2030”○Joji Tsurumoto,1 ○Yousuke Maezawa,2 Takao Saito1,3 (1Takasago ChemicalCorporation, 2Yokogawa Solution Service Corporation, 3iFactory Inc.)
12:00 - Lunch
12:40 - Exhibition and poster session
14:20 - Invited lecture (IL-4)“Scalable Flow Synthesis of Drug Scaffolds and Emulsion by Numberingup Microreactor Systems”
Dong-Pyo Kim (Pohang University of Science and Technology (POSTECH))
15:00 - Oral presentation (OP-08)“Scale-up of Flow Fine Synthesis”(1National Institute of Advanced Industrial Science and Technology (AIST), 2TOKYORIKAKIKAI CO, LTD (EYELA), 3The University of Tokyo)○Yasukazu Kobayashi,1 Yasuharu Morii,2 Teruhiko Tanaka,1 Nagatoshi Koumura,1 HajimeKawanami,1 Koichiro Masuda,1 Shun-ya Onozawa,1 Kazuhiko Sato,1 and, Shū Kobayashi1,3

15:20 - Oral presentation (OP-09)“Development of flow membrane reactor for esterification of acetic acid byzeolite membrane”○Motomu Sakai, Yuma Sekine, Masahiko Matsukata (Waseda University)
15:40 - Break
16:00 - Oral presentation (OP-10)“Pore-size tuned organosilica membranes for improved pervaporation
separation of organic solvent mixtures”○Toshinori Tsuru, Ufafa Anggarini, Hiroki Nagasawa, Masakoto Kanezashi(Hiroshima University)

16:20 - Oral presentation (OP-11)“Development of a continuous flow process for biaryls based on sequential
Suzuki-Miyaura coupling and supercritical carbon dioxide extraction”○Tomohiro Ichitsuka, Tatsuya Fujii, Marina Kobune, Takashi Makino, Shinichiro Kawasaki (National Institute of Advanced Industrial Science andTechnology (AIST))
16:40 - Invited lecture (IL-5)
Andreas Kirschning
17:20

Closing