Admission Guidefor International Students, 2025
(Doctoral Course)

The first examination ：5th-Nov(Tue),2024
The second examination：27th-Jan(Mon),2025

Depending on the situations of the first applications for 2025 graduate admissions,the second applications might be canceled.

Graduate School of Medicine, Nara Medical University
840 Shijo-cho, Kashihara, Nara 634-8521, Japan
Tel: +81-744-22-3051 Ext. 2401

The Details of admission requirements for
Graduate School of Medicine (Doctoral Course), Nara Medical University
1.Description for specialized subjects.
Specialized Subjects

Major Field

Field

Social andCommunity
HealthScienceSpecialized Subjects

Epidemiology
Public Health
Legal Medicine
Medicine Based Town
Medical Informatics and Hospital Management

Biomacromolecules
Molecular and Cellular Dynamics
Phasing Biology
Cellular and Molecular Anatomy

Basicscience forbiological
function anddisease
MedicalScience

Functional Morphology
Brain and Neurophysiology
Control Mechanics for Biological Function
Biology of Aging
Molecular Oncological Pathology
Bioprotection and Regeneration Medicine
Microbiology
Immunology (*NM course)
Signal Transduction in Pharmacology
Embryology
Advanced Medical Science of Thrombosis and Hemostasis
Applied Medical Science and Clinical Research
Cardiovascular System Research
Cardiovascular Medicine

Clinical and Pathological Nepkhrology
Respiratory Medicine
Hematology
Gastroenterology, Endocrinology and Metabolism
Clinicalmedicine for Diabetes and Endocrinology
Clinical Neurology and Myology
organ anddiseaseGastroenterological Surgery
control
Neurological Disorder Control
Circulatory and Respiratory Control Medicine
Musculoskeletal Reconstructive Surgery (*NM course)Sports Medicine
Bioregulatory Medicine of female genital organ-1-

Major Field

Field

Specialized Subjects

Ophthalmology and Vision Science
Newborn Health and Development
Child Health and Development
Psychiatry and Behavioral Neuroscience
Dermatology
Medical Science for Pathologic and Functional Control of
Urogenital Organs
Prostate Brachytherapy

MedicalScience

Otolaryngology-Head and Neck Surgery
Image-based Diagnosis and Minimal Invasive Therapy
Radiation Oncology
ClinicalAnesthesiology and Pain Medicine
medicine forClinical neuromonitoringorgan and
General Medicine and Clinical Pathophysiology
diseaseOral and Maxillofacial Surgery
control
Emergency Medical Science
Diagnostic Pathology
Medical Oncology
Rehabilitation Medicine
Clinical Laboratory Medicine
Bloodstream Reconstructive Medicine
Infectious Diseases
Clinical and Translational Science
Laboratory of Advanced Technology for Interventional Radiology
Proton Beam Radiation Oncology
Medical Sensing Technology

Note:
Applicants should directly ask inquiries, the details of research area or the number to be
accepted, to the supervisors related with the subject you are interested in.

*NM course
Subjects related to research and lectures in University of Michigan including

to study at University ofMichigan in the doctoral course of our university based on Memorandum of Understanding for Academic
and Scientific Cooperation Between the Regents of the University of Michigan on Behalf of its Medical
School and Nara Medical University (December 13, 2018)-2-

2.Requirements for admission
Those who have been in the university for a certain period of time (more than 6 months forstudents by private expanse) as research students of Nara Medical University and any of thefollowing (1) to (4).
(1)Those who had completed 18 years of education abroad (final courses must be medicine or
dentistry). Those who is more than 24 years old, had less than 18 years of education abroad (final
courses must be medicine or dentistry), and have studied more than approximately a year in any college,
university, or national research institution as a research student or a researcher(2) Those who given Bachelor’s Degree in medicine or dentistry as an international student in Japan(3) Those who given Master’s Degree in graduate course of the other majors as an international student inJapan or those who recognized as possessing scholastic abilities equivalent mentioned above by
graduate school of Medicine, Nara Medical University(4) Those who given Master’s Degree in graduate course of the other majors abroad or those who
recognized as possessing scholastic abilities equivalent mentioned above by graduate school of
Medicine, Nara Medical University
Note:
The graduate school committee may give the permission to those who meet in any of the above to undergo
the entrance examination.

3. Procedure for applying
Applicants need to submit documents described in (1) and (2) and pay examination fee
described in (2)-(C) to Student Division.
Documents in (1) and (2) are provided in Japanese or English(1) Documents for Judgment of eligibility for examination permission(a) Form for permission (use the form provided)(b) Resume (use the form provided)(c) Certificate of graduation or completion(d) School transcript of the most recent academic course studied(e) The Letter of recommendation: enclosed and signed by the university president or a professor of themost recent academic course studied(f) The letter of recommendation: issued by the Japanese governmental organizations or overseas
agencies of Foreign Affairs if the international student is supported by the Japanese government or
those of foreign countries(h) Certificate of identity (use the form provided)(i) Passport or a Copy of Residence card(j) Address card (for the notice of your pass and fail)Note:
If the certificate differs from the current family name, provide official documentation to provethat the family name has been changed. (Extract of family register issued within three(3)months or similar documents)-3-(2) Application for admission(a) Form for application (use the form provided)(b) Examination card and Photograph card (use the form provided)(c) Examination fee: 30,000 yen

Bank transfer(including by using a Japanese ATM) only.

Transfer the entrance examination fee (30,000 yen) to the following bank account via ATM orInternet banking.
【For Electronic Payment】
Beneficiary Name: Nara Medical University
Bank Name: Nanto Bank
Branch Name: Kashihara
Account Number: 0266177
Note 1: Enter the 'GMS' followed by the 'Applicant's Name' in the Applicant’s Name field of thetransfer information.

(e.g.) GMSTaroIdai

Note 2: Applicants will need to pay a fee when you transfer money.
Note 3: The transfer must be made within the following duration.

The first examination Tuesday, October 8 - Friday, October 11, 2024
The second examination Tuesday, Junuary 7 - Friday, Junuary 10, 2025
Note 4: The certificate of bank transfer or other payment proof of the entrance examination fee
will be attached to the Application Fee payment form. Please submit it with otherdocuments.

4.Deadline for applying
The first examination
For the documents related to 3-(1) described above need to submit to Student Division
9:00 am on2th-September (Mon) ～ 5:00 pm on 6th-September (Fri), 2024
*Office hours: From 9:00 to 17:00, Mon-Fri (except Japanese holiday)
If sent by mail, must arrive no later than 5:00 pm on Friday, September 6, 2024
For the documents related to 3-(2) described above need to submit to Student Division
9:00 am on 8th-Octorber (Tue)～ 5:00 pm on 11th-Octorber (Fri), 2024
*Office hours: From 9:00 to 17:00, Tue-Fri (except Japanese holiday)
If sent by mail, must arrive no later than 5:00 pm on Friday, October 11, 2024
The second examination
For the documents related to 3-(1) described above need submit to Student Division
9:00 am on 2th-December (Mon) ～ 5:00 pm on 6th-December (Fri), 2024
*Office hours: From 9:00 to 17:00, Mon-Fri (except Japanese holiday)
If sent by mail, must arrive no later than 5:00 pm on Friday, December 6, 2024
For the documents related to 3-(2) described above need to submit to Student Division
9:00 am on 7th- January (Tue)～ 5:00 pm on 10th-January (Fri), 2025
*Office hours: From 9:00 to 17:00 Tue-Fri (except Japanese holiday)
If sent by mail, must arrive no later than 5:00 pm on Friday, January 10, 2025

-4-

5.Any other inquiries
Student Division
Graduate School of Medicine, Nara Medical University
840, Shijo-cho, Kashihara, Nara 634-8521 Japan
gakuseik@naramed-u.ac.jp

6.Selection method
Admission will be determined based on the results of written examinations in foreign language and inspecialized subjects. Health certificate and transcript will be also required for consideration.
Examination
English and specialized subjects described below

The first examination
Examination date

Subjects

10:00 - 11:30

English

13:00 - 14:30

Specialized
subjects
First choice

Location

Writtentest or oral
answer test

To be notified
on the day

Oral answer test

To be notified
on the day

5th-Nov(Tue),
2024

14:40 - 16:10

Specialized
subjects
Second choice

The second examination
Examination date

10:00 - 11:30

English

13:00 - 14:30

Specialized
subjects
First choice

27th-Jan(Mon),

Subjects

2025

14:40 - 16:10

Specialized
subjects
Second choice-5-

Location

Writtentest or oral
answer test

To be notified
on the day

Oral answer test

To be notified
on the day

Note :(a)Dictionaries including medical term dictionary can be used; however, electronic dictionaries andmedical dictionary are not allowed to use(b)In case of oral examination in English is requested, schedule will be announced(c)International students will be able to take examination either Japanese or English(d)Examination for specialized subject will be performed by research instructors corresponding to thearea specified

7. Result
For the result of the first examination: 10th-December (Tue), 2024
For the result of the second examination: 4th-March (Tue), 2025
The Result will be shown on the bulletin board in our school and on our website.
The letter notice also will be delivered to successful applicants by mail later.

8. Procedure for admission
More details will be announced around on Mar, 2025.
Applicants who are granted admission will be required payment enrollment fee through any
financial institutions using our statement which will be mailed later, then need to submit
related documents described in (1) and (2) to Student Division.
(1) Documents(a) Pledge : signed by a guarantor (use the prescribed form )(b) Photograph: 4cm long x 3cm width, front view from the chest up with no hat and no backgroundtaken within the current three months (show your name and the date of taken it on the reverse side)(c)Certificate of Graduation: examinees who are expected graduation(d)Notification of Residence: use the prescribed form(e)Bank account transfer Request Form:: use the prescribed form
(2) Enrollment fee: ￥282,000, required the receipt

9. Tuition¥ 535,800 per a year: required payment in two semesters(April, October)
Note:
Graduate School of Medicine, Nara Medical University would possibly revise tuition fee without any
notification.

-6-10. Others(1) In case request to receive application form by mail, please enclosed a return envelope,size 33cm x 24cm mentioned your address and postage stamp ¥250（￥320 will be necessary after 1
October.） (domestic in Japan)(2) In case of to dispatch application documents by mail, please do so by registered express and show
“Admission application for the graduate school” with red ink on its envelope.
(3)After completed entrance formalities, specialized subjects can not be changed,and documents and fee
will not be returned for any reason.
(4)The examination card for the first examination given at Student Division ,9:00 to 9:30am on 5th-Nov (Tue), 2024
The examination card for the second examination given at Student Division,
9:00 to 9:30am on 27th-Jan (Mon), 2025
(5)Inquiries will be accepted by e-mail only. (igakukenkyuka@naramed-u.ac.jp)-7-FieldSpecialized
Subject

Professor

Saeki
Keigo
Epidemiology
ObayashiKenjiSocial andCommunity
HealthScience

ImamuraTomoakiPublic Health,
HealthManagement andPolicyNoda
Tatsuya
MyojinTomoyaResearch Field
Our chrono-epidemiologic studies are derived from data at real-lifesituation of community-based cohort. At baseline, we
simultaneously measure environment factors (temperature, light, andnoise), behavioral factors (food intake, exercise, and bathing),
biological rhythm (ambulatory blood pressure, physical activity,
body temperature, melatonin secretion, and sleep/awake status), and
we longitudinally follow the change of physical and cognitive
function and incidence of cardiovascular disease and cancer. We areinterested in the time of the exposure, and the time of outcome in theassociation between exposure and outcomes as follows:
1) Environment/behavior and biological rhythm
・Temperature vs. blood pressure
・Light vs. objective sleep, and nocturia
・Light vs. melatonin secretion
・Bathing and blood pressure
・Breakfast skipping vs. obesity2) Environment/behavior and disease
・Light vs. obesity, dyslipidemia, diabetes, depression, carotid intima
media thickness
・Light/temperature vs. incidence of cardiovascular disease andcancer3) Biological rhythm and disease
・Melatonin secretion vs. depression,cognitive function, muscle
strength, and chronic inflammation.
1. Evidence-Based Public HealthStudies on:
・Epidemiology and establishing analytical systems using big data:
National Database (NDB), National Insurance/Kokuho Database(KDB), and Diagnostic Procedure Combination (DPC)
・Consolidation of databases (DB) for medicine, healthcare, nursing
care, intractable diseases, and disorders
・Food defense and cohort study on the Kanemi Yusho incident (foodpoisoning with PCB)・Risk communication in medicine, healthcare and food・Medical care and nursing care for the aged using DBs of medicine andnursing care
・Healthcare communication between healthcare providers and patients
And their family members
2. Health Management and Policy
Studies on:
・ Investigation and policy recommendations for developing bothnational and community-based health plans as well as nursing carebusiness plans
・Cost effectiveness in medicine and health, and economically efficient
allocation and use of diagnostic imaging equipment
・Improvement in hospital management
・Reimbursement of medical service fees, and break-even point inhealthcare services
・Cooperation between medical services and nursing care the time ofpatient discharge
・Transferring and sharing workloads (task shifting and sharing) frommedical doctors to other healthcare providers-8-FieldSpecialized
Subject

Professor

Research Field
1. Study on effect of ethanol on vascular function

Legal Medicine

Kasuda2. Study on relationship between vascular function and sudden death

Shogo

3. Study on effect of ethanol on sepsis
4. Study on effect of ethanol on thromsosis
1. Designing a concept for social hospital associated withmedical knowledge and technology
2. Evaluation systems of IoT-oriented environmental data andvital signs
3. An administration model and policy toward making society where
people live independently
4. Healthcare management systems and its platforms
5. Evaluation methods and analysis of BIC data from medical healthdata
6. Healthcare index, and the prediction of illness risk
7. Tools for rehabilitation and care management
8. Locomotive syndrome and the extension of healthy life

Medicine BasedUmeda

expectancy

Town

Tomohiro

9. MBT creating innovation
What is MBT?
It stands for medicine based town. You can see a lot of system andarchitectures using medical knowledge/ wisdoms in this type ofSocial andCommunity
HealthSciencetown. Medical knowledge/wisdoms come from many kinds ofclinical doctors or scientists in medical university, and therefore itis huge. Using medical knowledge adds extra values on thetowns. This concept would be novel for creating new types of town,
creating new industry and stimulating local community.
IoT: Internet of ThingsAbout IoT
IoT stands for Internet of Things, indicating that any types of things
are connected to IT-related apparatuses such as a mainly PC, aserver and the printer1. Strategic promotion of medical information cooperation
2. Telemedicine support using mobile devices
3. Implementation of standards in the hospital information system
Tamamoto
Medical Informatics
and HospitalManagement

TetsuroSuto
Shunji

4. Effective utilization of the patient condition adaptive path system
5. Improvement and improvement of the quality of medical carebased on medical information data
6. Medical safety based on medical information data
7. Medical management based on medical information data
8. Human resource development and career support to promote theutilization of medical information
9. Human resource development and career support for the practiceof hospital management-9-FieldSpecialized
Subject

Professor

Research Field

Sakai

1. Design and synthesis of artificial red cells and transfusion

Hiromialternatives
2. In vivo efficacy evaluation of artificial red cells

Biomacromolecules

Yamamoto

3. New clinical application of artificial red cells

Keizo

4. Study on new micro-and nano-encapsulation
5. Purification and chemical modification of biomacromolecules

Matsuhira

6. X-ray crystallography and functional evaluation of proteinsTakashi

7. Study on new materials for biomedical application

Nagafuchi
Molecular andCellular Dynamics

Akira
Kobayashi
Chiyoko

1. Cytoplasmic regulation of cadherin-mediated cell adhesion
2. Contact regulation of cell growth
3. Contact regulation of cell rearrangement
4. The roles of cadherin-based cell adhesion on epithelial
morphogenesis
5. Abberant cell-cell adhesion system and cancers
1. Biological roles of LC-domains in phase separationBasicscience forbiological
function anddiseasePhasing Biology

Mori
Eiichiro

2. Pathological mechanisms of uncontrolled phase separation
3. Atomic resolution molecular structure of phase separation
4. Genomic stability maintenance5. Controlling organogenesis in a dish1. Vascular endothelial function in health and diseases

Cellular andMolecular Anatomy

Inoue
Koichi

2. Optogenetic approach to the non-neural systems
3. Molecular mechanism of stroke and neuropsychiatric disorders
4. Dynamics and importance of zinc in the nervous system
1. Molecular mechanisms of development and differentiation of thenervous system

TatsumiFunctional
Morphology

Kouko
TanakaTatsuhide

2. Molecular mechanisms of stress or injury responses of neurons andglia
3. Functions of Glial cells in the nervous system
4. Development of regenerative therapy for injured neurons
5. Differentiation of neuronal stem cells and its application toregenerative medicine
1. Neural mechanisms of velocity-position signal transformation in

Brain and
Neurophysiology

Saito
Yasuhikoeye movement system
2. Electrophysiological properties of brainstem neurons thatparticipate in eye movement-10-FieldSpecialized
Subject

Professor

Research Field
1. Identification of novel regulators of ES cell pluripotency

Control Mechanics
for Biological
Function

Horie
Kyoji

2. Epigenetic regulation of ES cell pluripotency
3. Mechanism of iPS cell generation
4. Development of genetic method for high-throughput analysis
of gene function
1. Elucidation of molecular and cellular mechanism of aging using
model organisms (yeast, nematode, mouse, etc.)
2. Elucidation of role and regulation of autophagy in aging and age-

Biology of Aging

Nakamura
Shuheirelated diseases
3. Elucidation of molecular and cellular mechanism to maintainlysosomal homeostasis and its role in aging
4. Elucidation of molecular and cellular mechanism of inter-organelle
communication and its role in aging
1. Molecular mechanisms of cancer development and metastasis in
human digestive organ cancers

Basicscience forbiological
function anddisease

2. Animal models for environmental and genetic factors incarcinogenesis
Molecular
Oncological
Pathology

3. Animal models for cancer metastasis and its prevention andKuniyasu
Hirokitreatment
4. Prediction of metastatic capacity in human cancers
5. Cancer and life styles
6. Cancer-host microenvironment
7. Differences in carcinogenic mechanisms between experimental
animals and humans
8. Association of cancer with lifestyle and lifestyle-related diseases
1. Reserch on ES/iPS cell differentiation– Induction of hepatocytes , insulin-producing cells, dopamine
producing cells, inner ear hair cells, alveolar epithelial cells, etc.–
2. Cell transplantation therapies for spinal cord injury,

Bioprotection andRegeneration
Medicine

Ouji
Yukiteru

Parkinson’s disease, liver diseases, diabetes mellitus, and deafness
3. Regenerative medicine using mesenchymal stem cells and follicle
stem cells
4. Analysis of signal transduction in trichogenesis
5. Host responses against intestinal helminth and protozoa
6. Rerearch on infection control using trematodes
7. Research on tick-borne infections-11-

FieldSpecialized
Subject

Professor

Research Field
1. Research on mechanisms of β-lactam-resistant bacteria

Yano
Hisakazu
Microbiology

2. Molecular epidemiology of β-lactamase-producing Gram-negative
bacilli
3. Analysis for spread of drug-resistant bacteria in a clinical setting

NakanoRyuichi

4. Pathogenicity and drug resistance of bacteria causing respiratory
tract infection
5. Infection control for drug-resistant bacteria in a hospital
1. Immunological analysis of pathogenesis using various kinds ofmouse model-Respiratory infectious model, Bronchial asthma model, Lung
fibrosis model, Sepsis model, Autoimmune disease model, Cancer

Ito
Immunology(NM course)

Toshihiromodel, Inflammatory bowel disease model (NM course)
2. Analysis of immune regulation mechanism by epigenetics-Influenza virus, Allergy(NM course)

Kitabatake
MasahiroBasicscience forbiological
function anddisease

3. Analysis of the linkage between innate and acquired immunity by
Notch signaling
4. Analysis of host immune mechanism and development of vaccines
against multi-drug resistant bacteria
5. Immunological analysis of multiple functions for non classical
HLA
1. Explore the role of oxidative stress in the progression ofatherosclerosis
2. Development of new drugs for atherosclerosis from natural foodnutrients
3. Mechanisms of vasoactive substance-induced vascular remodelingSignal Transductionin Pharmacology

Yoshizumi
Masanoriin hypertension and atherosclerosis
4. Investigation into the molecular mechanisms and pharmacologicalintervention for angiogenesis

Nakahira
Kiichi5. Analysis of intracellular signal transduction of insulin resistance invascular smooth muscle cells
6. Explore the role of oxidative stress in the progression ofneurodegenerative diseases
7. Protein S-nytorsylation and diseases
8. Investigation into the mechanisms of intracellular signaltransduction in neural type nicotinic acetylcholine receptor-12-FieldSpecialized
Subject

Professor

Research Field
1. Development of single-cell omics methods combined withhistology
2. Research for mechanisms of germ cell development

Embryology

Kurimoto

3. Research for mechanisms of quality control of germ cells

Kazuki

4. Research for mechanisms of epigenome reprogramming ofprimordial germ cells
5. Research for mechanisms of potential pluripotency in primordial
germ cells
1. Research of coagulation and fibrinolytic factors in inflammatory
diseases
2. Research of coagulation and fibrinolytic factors in metabolic
diseases
3. Research of coagulation and fibrinolytic factors in diseases ofAdvanced MedicalBasicscience forbiological
function anddiseaseScience of

TatsumiThrombosis andKohei

premature infants
4. Study on the relationship between aging and coagulation /fibrinolytic factors

Hemostasis

5. Research on the treatment of blood coagulation disorders using
mesenchymal stem cells, ES cells, and iPS cells
6. Research on the molecular pathogenesis of cancer-associatedthrombosis
7. Research of coagulation and fibrinolysis system in organ linkage
Yoshizumi
Applied Medical
Science and ClinicalResearch

Masanori
KashinoGenrouKokameKoichi
Cardiovascular
System Research(Central Medical Research Facilities)
Research of the radiation effect

1. Functional Regulation of the Cardiovascular and Coagulation
System
2. Signal Transduction and Transcriptional Regulation in

Nakagawa
Osamu

Cardiovascular and Coagulation Systems
3. Etiologies of Human Congenital/Hereditary Diseases Related to
Cardiovascular Development and Blood Coagulation-13-

FieldSpecialized
Subject

Professor

Research Field
1. Study for molecular mechanism of heart failure
2. Study for molecular mechanism of multi-organ interactionin heart failure
3. Genetic analysis of cardiomyopathy and its clinical application for
diagnosis
4. Clinical study using biopsied samples in left ventricle

HikosoCardiovascular
Medicine

Shungo5. Study for pathophysiology of coronary artery diseases using
optical coherence tomography
6. Registry study of heart failure and acute myocardial infarction

Watanabe

7. Development of new quality indicators for healthy life expectancy

Makoto8. Study for new cardiovascular imaging technique using MRI
9. Development of new technology for Imaging Analysis using
Artificial Intelligence
10. Epidemiological study for cardiovascular managing using current
big data
11. Research for the utility of arrhythmia detection with implantableloop recorder on management in patients with heart failure
1. Involvement of kidney interstitial fibrosis in the progression ofClinicalmedicine fororgan anddiseasecontrolchronic kidney disease
2. Involvement of kidney tubular damage in nephrotic syndrome
3. Involvement of dyslipidemia in the development and progressionof chronic kidney disease
4. Investigation of factors affecting postoperative acute kidney injury
5. Elucidation of the mechanism of vascular calcification associatedTsuruyaKazuhiko
Clinical andPathological
Nephrology

Samejima
Kenichi
EriguchiMasahirowith chronic kidney disease
6. Investigation of factors associated with mortality and kidney
prognosis in patients with chronic kidney disease using specified
health check-up mega-data
7. Association between kidney biopsy pathologically findings andkidney prognosis in diabetic nephropathy
8. Association between urinary FSP-1 and kidney prognosis inchronic kidney disease
9. Association between steroid treatment during relapse phase andkidney prognosis in IgA nephropathy
10. Efficacy of low-dose steroid therapy in minimal change disease
11. Involvement of sympathetic nervous system in cardiorenal
syndrome
12. Relationship between dialysis modality and progression ofcoronary artery calcification and brain atrophy-14-FieldSpecialized
Subject

Professor

Research Field

Muro
Shigeo

1. Pathogenesis and mechanisms of airway remodeling / pulmonary

Yamauchi
Motoo
Respiratory Medicine

HontsuShigetoYamamoto
Yoshifumi

vascular remodeling
2. Regenerative medicine in epithelial and endothelial cells of the lungin patients with pulmonary emphysema
3. Analysis of the pathogenesis, nutritional metabolism anddevelopment of new treatment for COPD
4. Establishment of disease diversity and individualized treatment of
sleep apnea syndrome
5. The role of chemokines and dendritic cells in the autoimmune andallergic diseases

FujitaYukio

6. Molecular mechanisms of growth and progression in lung cancer
7. Construction of the “tailor-made therapy” for lung cancer
1.Pathophysiological analysis of thrombosis and bleeding events
associated with myeloproliferative neoplasms (MPNs)
・Pathophysiology of acquired von Willebrand syndrome (AVWS)
associated with MPN・Development of a novel method to assess thrombotic and bleedingrisk in MPN
・Analysis of platelet function in MPN

Clinicalmedicine fororgan anddiseasecontrol

2. Pathophysiological analysis of complications in hematopoietic
Hematology

Masanori
Matsumotostem cell transplantation
・Pathophysiological analysis and investigation of early diagnostic
markers for transplantation-associated thrombotic microangiopathy(TA-TMA) and sinusoidal obstruction syndrome (SOS)・Pathophysiological analysis of complement involvement intransplantation-associated complications
3. Pathophysiological analysis and investigation of treatment for
thrombotic and hemorrhagic complications associated withhematologic malignancies and their therapeutic agents
4. Development of a new rapid diagnostic assay for ADAMTS13 inthrombotic thrombocytopenic purpura (TTP)

Yoshiji
Hitoshi

1. Pathophysiology of ascites and spontaneous bacterial peritonitis
2. Endotoxin, innate immunity and digestive diseases
3. ADAMTS13 abnormality in liver, biliary and pancreatic diseases

MitoroGastroenterology andMetabolism

Akira

4. Liver regeneration (from embryonic stem cells to hepatic stem
cells)
5. Pathophysiology of nonalcoholic steatohepatitis

NamisakiTadashi

6. Anti-angiogenesis treatment for hepatocellular carcinoma
7. Pathophysiology of liver fibrosis
8. Pathophysiology and treatment of acute hepatic failure

Kaji
Kosuke9. Liver transporter in liver diseases
10. Pathophysiology of digestive and liver disorders in the elderly-15-FieldSpecialized
Subject

Professor

Research Field
1. Big data analysis of diabetes, endocrine and metabolic diseases
using claimed data base including National Database
2. Elucidation of pathophysiology of diabetes, endocrine andDiabetes andEndocrinology

Takahashimetabolic diseases, especially pituitary and adrenal diseases

Yutaka

3. Pathophysiological study of endocrine immune related adverse
event in immune checkpoint inhibitor

Okada

4. Epidemiological study on the risk of diabetes and obesity

Sadanori

5. Pathophysiological study on diabetes and obesity
6. Pathophysiological study of paraneoplastic autoimmune
hypophysitis including Anti-PIT-1 hypophysitis, isolated ACTH
deficiency, and immune checkpoint inhibitor-related hypophysitis

Sugie
KazumaKataoka
Hiroshi

Clinicalmedicine fororgan anddiseasecontrol

Clinical Neurology

Saito

and Myology

Kozue
Izumi
Tesseki
Kiriyama
Takao

1.Neurogenetic and pathological mechanism of neuromusculardisorders
2.Molecular mechanism of autophagy in neurological andmycological disorders
3.Pathomechanism of Parkinson’s disease
4.Pathomechanism and therapeutic study of central vervous system
infections
5.Neuroradiological study of stroke
6.Pathomechanism of demyelinationg disorders in central nervous
system
7.Neurophysiological study of neuromuscular ddisorders

1. Molecular biological study for development,progression andmetastasis of gastorointestinal and hepato-biliary-pancreatic cancer
Sho
Masayuki

Gastroenterological
Surgery

KoyamaFumikazu

2. Less-invasive surgery and functional surgery for resection of
gastorointestinal and hepato-biliary-pancreatic cancer
3. Development of new strategy of chemotherapy,immunotherapy andgene therapy for digestive for gastorointestinal andhepato-biliary-pancreatic cancer
4. Research for pathogenesis and treatment for inflammatory bowel

Matsumoto
Sohei
Akahori
Takahirodisease5. Clinical and experimental research for liver,pancreas,and small
bowel transplantation
6. Study for gastorointestinal motility in digestive surgery
7. Development of new techniques in abdominal and transplantation
surgery-16-

FieldSpecialized
Subject

Professor

Nakagawa
Ichiro
Neurological

Boku

Disorder Control

Eishu

Nishimura
Fumihiko

HosonoCirculatory andRespiratory Control
Medicine

Mitsuharu
Sawabata
Noriyoshi

Clinicalmedicine fororgan anddiseasecontrol

TanakaYasuhito
Omokawa
Shohei
Honoki
Kanya
Kido
Akira
Musculoskeletal
Reconstructive
Surgery(NM course)

Taniguchi
Akira
Ogawa
Munehiro
Kawamura
Kenji
Shigematsu
Hideki
InagakiYuusukeResearch Field
1. Basic study on pathophysiology of brain ischemia
2. Basic study on pathophysiology of cerebral venous circulation
disorders
3. Basic study on hypoxic brain injury (neuron damage)
4. Basic and clinical study of the acquisition of epileptogenesity
5. Study of the mechanism of electroencephalographic activity
6. Study on the mechanism and surgical management of spinal cord
injury7. Analysis for the regulatory mechanism of brain tumor
8. Experimental study of the mechanisms responsible for thedevelopment and growth of dural arteriovenous fistula
9. Clinical and basic study of the treatment for involuntary movement
1. Research on surgical treatment for valvular disease
2. Research on ischemic heart disease
3. Research on circulatory assist device
4. Research on regenerative medicine of the heart
5. Research on less(minimally) invasive cardiovascular surgery
6. Research on ischemic reperfusion injury of the heart
7. Basic and clinical research on the occurrence,metastasis,andrecurrenceof pulmonary and mediastinal malignancies
8. Research on minimally invasive surgery for pulmonary andmediastinal malignsncies
9. Basic and clinical research on small circulation function in thoracic
surgery
10. Basic and clinical research on degenerative lung deseases(emphysema,pulmonary fibrosis,etc.)in thoracic surgery
1. Explication for pathogenesis of musculoskeletal diseases
2. Elucidation for biomechanical genesis of degenerative diseases
3. Experimental study for bone regeneration using mesenchymal stemcells
4. Clinical research of bone regeneration using bone marrow
5. Basic and clinical research of regenerative cartilage using MSC
6. Development and clinical application of orthpaedic artificial
material
7. Development of new surgical treatment for rheumatoid arthritis(NM course)
8. Explication for a fracture healing process and development of
fracture treatments
9. Explication for pathogenesis of enthesopathy and clinicalapplication of its treatments
10. New developments for total ankle prostheses
11. Development of stem cell biology to elucidation and treatment ofsarcoma
12. Development of new donor-site for extremity reconstruction withmicrosurgical technique
13. Bone and joint reconstruction with the use of tissue engineeringand microsurgery
14. Development of ultrasonography assisted procedure fororthopedic surgery
15. Clinical research on microsurgery(NM course)
16. Development of new rehabilitation approach-17-FieldSpecialized
Subject

Professor

Research Field
1. Elucidation of the mechanism for musculoskeletal overuse

TanakaYasuhitoSports Medicine

Ogawa
Munehirosyndrome
2. Ultrasonographycal analysis for the pathomechanism of sports
related injuries
3. Clinical utility of acceleration training for the functional recoveryof sports related injuries

Inoue
Kazuya4. Basic research of the cycling(pedaling) exercise for locomotive
syndrome
5. Utility of medical fitness for community medicine
1. Investigator-initiated clinical trial for patients with gynecologicalcancers through the treatment of anti-metastatic compounds
2. Development of anti-metastatic gene therapy for patients withovarian cancer
3. Development of a drug discovery system for anti-metastatic
compounds based on quantum chemical calculations
4. Elucidation of the invasion mechanism of gynecological cancers

Clinicalmedicine fororgan anddiseasecontrol

5. Elucidation of genes that regulate drug sensitivity to anticancer
agents
6. Elucidation of genes involved in malignant transformation ofendometriosis
KimuraBioregulatory
Medicine of female
genital organ

Fuminori

7. Genetic analysus of familial uterine cancer and elucidation of
causative genes
8. Development of diagnostic criteria for adenoma malignum and

Kawaguchi
Ryujirelated diseases
9. Research on mass screening for early detection of ovarian cancer
10. Investigation of the mechamism of deep vein thrombosis during
pregnancy and the postpartum period
11. Research on analysis of the mechanism of onset of preeclampsia
12. Research on the effects of anti-inflammatory compounds on
preeclampsia
13. Research on the prevention of endometriosis and development of
the method for its symptom relief
14. Research on the efficacy of ovarian tissue cryopreservation forcancer patients
15. Research on the development of a procedure for ovarian tissue
cryopreservation and autologous transplantation for cancer patients-18-

FieldSpecialized
Subject

Professor

Research Field

1. Research on Retinal pigment epithelium and cytokine
2. Studies of development in pediatric visual function
Ueda
TetsuoOphthalmology and

Nishi

Vision ScienceTomo

3. Mechanism of age-related macular degeneration
4. Studies of clinical treatment on age-related macular degenerationand macular hole
5. Mechanism of diabetic retinopathy
6. Studies of clinical treatment on diabetic retinopathy

Tsujinaka

7. Studies of neuroprotection

Hiroki

8. Studies of ocular blood flow
9. Cohort studies of visual acuity on aged people
10. The effect of the ocular diseases to the circadian rhythm
1. Biochemical and molecular studies on pathogenesis andpathophysiology of congenital hemorrhagic disorders(hemophilia,von Wiillebrand disease,etc.)

Clinicalmedicine fororgan anddiseasecontrol

2. Biochemical and molecular studies on pathogenesis andpathophysiology of congenital thrombotic disorders
NogamiNewborn Health andDevelopment

Keiji(antithrombin,protein C,protein S,ADAMTS 13 deficiency,etc)
3. Pathogenesis and pathophysiology of acquired hemorrhagic andOgiwaraKenichithrombotic disorders
4. Physiological and pathological analysis of thrombus formation
5. Liver transplantation (APOLT) and gene/cell therapy for hemophilia
6. Studies on hemorrhagic and thrombotic disorders in premature andneonatal infants
7. Genetic councelling for congenital and hereditary diseases
1. Pathological analysis of neonatal intraventricular hemorrhage fromblood coagulation mechanism

Child Health andDevelopment

UchidaYumiko2. Elucidation of blood coagulation control mechanism involved in
the development of neonatal chronic lung disease
3. Pathophysiological analysis of bilirubin encephalopathy in preterm
infants-19-

FieldSpecialized
Subject

Professor

Research Field

1. Research on early interventions for neuropsychiatric disorders
2. Neurophysiological studies of neuropsychiatric disorders inchildren and adolescents
3. Neuromodulation research for neuropsychiatric disorders
4. Cognitive rehabilitation of neuropsychiatric disorders
5. Brain imaging and neurophysiological research on
Okada
Takashi
Psychiatry and
Behavioral

Yamauchi

Neuroscience

Takahira

neuropsychiatric disorders
6. Research on interventions for individuals with challenging
behavior
7. Research on animal models of neuropsychiatric disorders using
behavior science and cell histology
8. Research using animal models by manipulating gene expression
and environmental factors
9. Pathophysiological and cognitive neuroscience research onneurodevelopmental disorders
10. Mental health literacy and stigma research

Clinicalmedicine fororgan anddiseasecontrol

11. Artificial intelligence (AI) analysis of large-scale clinicalinformation
1. Studies on innate immunity in atopic dermatitis and developmentof new treatments
2. Studies on pathogenic role for microorganisms in allergic skindiseases
Asada
Hideo
Kuwahara
Dermatology

Masamitsu
Shinkuma
Satoru3. Studies on pathogenic mechanism of severe drug eruption anddevelopment of new diagnostic methods
4. Development of a novel herpes zoster vaccine
5. Studies on pathogenic mechanism of SLE
6. Studies on the orientation of cutaneous collagen fibers
7. Immunohistochemical studies on cutaneous adnexal tumors
8. Studies on the usefulness of ultrasonography in dermatology

MiyagawaFumi

9. Development of a new treatment for porokeratosis
10. Elucidation of the pathological mechanism of hereditary skindiseases
11. Development of regenerative medicine and gene therapy for
epidermolysis bullosa-20-

FieldSpecialized
Subject

Professor

Research Field
1. Urodynamics○Development of novel urodynamic evaluation using telemetry
system○Mechanism of nocturnal polyuria: the effect of body water
distribution
2. Chronic renal failure and renal transplantation

Fujimoto○Influence of microflora on Chronic renal transplantation patients

Kiyohide○Body composition analysis for optimal hemodialysis

Medical Science for3. Renal cell carcinoma

Pathologic andTanaka○Evaluation of split renal function following renal surgery;

Functional Control of

Nobumichi

3D-image analysis

Urogenital Organs○Immunological mechanism of combination with cytokine andYonedaTatsuomolecular targeting therapy
4. Urotherial carcinoma○Photodynamic diagnosis of superficial bladder cancer○Methylation analysis in urotherial carcinoma
5. Prostate carcinoma○Radiosensitization○Chemoprevention for prostate cancer

Clinicalmedicine fororgan anddiseasecontrol

6. Sleep disorder and voiding dysfuncton
TanakaNobumichi

Clinical and basic research for low-dose-rate brachytherapy and highdose-rate brachytherapy concerning improvement of oncologic

Prostate

Fujimoto

outcomes, preservation of quality of life (QOL) and control ofbrachytherapy

Kiyohide

adverse events

Asakawa
Isao

Focal therapy of brachytherapy
Development of radiation modifiers

1. Molecular Mechanisms of tinnitus generation in thauditory
pathway
2. Stress and Meniere’s disease

Otolaryngology-Headand Neck Surgery

Kitahara

3. Equilibrium disturbance and vertigo

Tadashi

4. Sensory medicine in sports
5. Molecular Mechanisms of cholesteatoma generation

Yamanaka

6. Ultrasound hearing

Toshiaki

7. Development of ultrasound hearing aids
8. Evaluation of the speech perception ability and hearing aids
9. Molecular biology for head and neck cancer
10. Thyroid gland and salivary glands-21-

FieldSpecialized
Subject

Professor

Research Field

1. Diagnostic imaging and IVR in neuroradiology
2. Throracic imaging and IVR
TanakaToshihiro

3. Endovascular therapy for aortic disease
4. MRI study for abdomen and pelvis
5. IVR for malignant tumor

Image-based
Diagnosis andNishiofuku

6. IVR for chronic pain

Minimal Invasive

Hideyuki

7. IVR in palliative treatment

Therapy

8. IVR for emergency disease
Ichihashi
Shigeo9. Radiation dose reduction during IVR procedure
10. Percutaneous biopsy and gene diagnosis
11. Inovation of new contrast agents
12. Tumor immune microenvironment in IVR

Clinicalmedicine fororgan anddiseasecontrol

Radiation Oncology

Isohashi
Fumiaki

1. LQ model and fractionation schedules in radiation therapy

AsakawaIsao

3. Radiation biology of heavy ion therapy and proton therapy

Tamamoto
TetsuroKawaguchi
Masahiko

2. Radiation biology and physics of high-precision radiotherapy

4. Optimization in radiotherapy for lung cancer
5. Optimization in brachytherapy for prostate cancer
6. Optimization in radiotherapy for brain tumor
1. Study on cerebral and spinal cord protection
2. Study on cerebral and spinal cord monitoring

Anesthesiology andPain Medicine

Hayashi
Hironobu

3. Study on postoperative complications
4. Study on safety and quality of perioperative managements

Egawa
Jinji

5. Study on airway managements
6. Study on pain management for cancer patients

Naito
YusukeKawaguchi
Masahiko

Clinicalneuromonitoring

Nakagawa
IchiroHayashi
Hironobu
Shigematsu
Hideki

7. Study on chronic pain management
1. Study on EEG in perioperative period
2. Clinical research on neuromonitoring
3. Basic research on neuromonitoring
4. Study on monitoring of blood flow and metabolism in brain andspinal cord
5. Research on new instruments in neuromonitoring-22-

FieldSpecialized
Subject

Professor

Research Field
1. Theoretical analysis of the practice of general medicine
2. Study for evaluating clinical significance of the physicalexamination
3. Pathophysiological analysis for various diseases based onhemostatic perspective
4. Pathophysiological analysis for various diseases using

General Medicine andClinicalPathophysiology

Yoshimoto
Kiyomiexperimental mouse model
5. Study for the pathophysiology of collagen disease
6. Study for the practice of disaster medicine
7. Research on the Effectiveness of Primary Care in Health Care
8. Clinical research on epidemiology, diagnosis, and treatment inprimary care settings
9. Research on health care delivery systems regarding team building,information sharing, and service delivery systems
10. Educational research on medical education and lifelong learning
1. Minimally invasive surgery and functional preservation for oral
cancer patients

Clinicalmedicine fororgan anddiseasecontrol

2. Preoperative adjuvant therapy for advanced oral cancer
3. Clinical and besic study on prevention of ARONJ
4. Malignant transformation of oral precancerous lesions
Yamakawa
Oral and
Maxillofacial Surgery

Nobuhiro
YagyuuTakahiro

5. Reconstruction of oral and maxillofacial region
6. Diagnosis and treatment for temporomandibular joint disorders
7. Oral management in patients with dry mouth
8. Oral management in patients with systemic disease
9. Sedative control during oral surgery
10. Clinical study on speech, swallowing and masticatory disorders
11. Fixation of maxillary and maudibular bone flagments based on
biomechanics
12. Development of maxillofacial structure
13. Regenerative medicine of maxillofacial bone using tissue
engineering
1. Study of prehospital care for out-of-hospital arrest

Emergency Medical
Science

Fukushima
Hidetada

2. Developmennt of rapid identification for blood stream infection
3. Study of coagulation abnormalities in emergency and critical care
4. Geospatial analysis of prehospital emergency care
5. Immediate implementation of hemodialysis for acute kidney injury-23-

FieldSpecialized
Subject

Professor

Research Field
1.Clinicopathological studies using surgical, cytological and autopsy
specimens＊Histologic and morphologic study

Yoshizawa＊Immunohistochemical study

Akihiro＊Molecular study
2. Pathological image analysis using deep learning model

Diagnostic Pathology

TakedaMaiko＊Development of morphological recognition algorithm using weakly
supervised data
＊Investigation of tumor grading using multiscale network

Uchiyama
Tomoko3. Study of disease mechanisms by molecular biological analysis
using human tumor cells＊Molecular biological studies on tumor development andprogression＊Study for Epigenetic tumor-related genes
1.Investigation of molecular mechanisms related to the cancer

Clinicalmedicine fororgan anddiseasecontroldevelopment, progression and prognosis.
Takeda2.Functional analysis of novel genetic mutations identified in

Masayuki

precision medicine.

Medical Oncology

3.Investigation of resistance mechanisms in driver-positive tumors.
Yoshii

4.Development of new drugs across organs

Yumi

5.Genomic pharmacological research
6.Research contributing to standardization of supportive andpalliative fields

Kido

1. Pedagogy for rehabilitation medicine

Akira

2. Impairments-driven cancer rehabilitation
3. Physical activity in the frail elderly

Rehabilitation

Mano

MedicineTomoo

4. A novel multimodal prehabilitation program for perioperative
patients
5. The fun in the acquisition process of the activity

TanakaYasuhito

6. Activity-included life style model for extension of healthy life
expectancy
1.Research on usability of clinical examination

Clinical Laboratory

Yamazaki

2.Reaearch on prevention of reactivation of hepatitis B virus infection

Medicine

Masaharu

3.Research on pathophysiology of heart failure using
echocardiography-24-FieldSpecialized
Subject

Professor

Research Field
1. Analysis of thrombotic maicroangiopathy (TMA)・Japanese TMA registry
・ADAMTS13 gene analysis in congenital thrombotic
thrombocytopenic purpura (cTTP or Upshaw-Schulamn syndrome)
・Development of novel therapeutic agents for TTP

Matsumoto
Bloodstream

Masanori

Reconstructive
Medicine

Sakai
Kazuya・Analysis of pathophysiology in patients with TMA associated withhematopoietic cell transplantation
2. Diagnosis and treatment of von Willebrand disease
3. Analysis of acquired von Willebrand syndrome (AVWS)
・AVWS associated with myeloproliferative neoplasm
・AVWS associated with cardiovascular disorders
・Development of a therapeutic anti-ADAMTS13 inhibitory
antibody for AVWS
4. Dynamic analysis of von Willebrand factor (VWF)/ADAMTS13
axis under sheer stress
5. Research on VWF/ADAMTS13 axis in hepatic disorders.
1. COVID-19 infection

Clinicalmedicine fororgan anddiseasecontrol

2. Interaction between host and microorganism in
infectious diseases
3. Host defense and its control in respiratory tract infection
4. Biological activity of antimicrobial agents against
Infectious Diseases

Kasahara
Kei

resistant bacteria
5. Pathogenesis and treatment of HIV infection
6. Early diagnosis and multidisciplinary treatment of
deep-seated fungal diseases
7. Molecular epidemiology of drug resistant bacteria
8. Appropriate use of antimicrobial agents
9. Prevention of healthcare-associated infections
10. Social implementation of infection prevention technologies

Kasahara
MasatoClinical andTranslational Science

Asada
Kiyoshi
Kurakami
Hiroyuki

1. A research regarding the implementation and support of theindustry-initiated clinical trials and investigator-initiated clinical
trials
2. A research regarding the implementation and support ofthe post-marketing clinical trials
3. A research regarding the implementation and support of

TakeuchiJiro

the cohot study-25-

FieldSpecialized
Subject

Professor

Research Field
The aim of our laboratory is to investigate advanced and novel

Laboratory of
Advanced
Technology forInterventional

technology for interventional radiology.
Anai
HiroshiRadiology

1. Fundamental research of percutaneous ablation
2. Fundamental and innovative research of devices for interventional
radiology
3. Research and development of image guidance
4. Clinical application of new technology for interventional radiolog
1. Research on the range calculation with dual energy CT in proton
radiotherapy
2. Research on the range measurement in patients with off-line PET

Clinicalmedicine fororgan anddiseasecontrol

3. Research on the relative biological effectiveness of proton beams
4. Research on the effect of neutron in proton radiotherapy
Proton BeamYoshimura

Radiation Oncology

Hitoshi

5. Research on the inter-fractional variation measurement with inroom CT
6. Research on the variation of the bladder volume estimation
between in-room CT and echography
7. Research on the robust treatment planning of proton radiotherapy
8. Research on the dose distribution comparison between proton
radiotherapy and photon radiotherapy

Yamamoto
Medical Sensing
Technology

Kouhei
KodamaHidekazu

1. Mechanism of bone, cartilage and air conductions hearing andoptimum of cartilage conduction hearing aids.
2. Development of vital signal sensing methods utilizing electroacoustic transducers combined with hearing aids.

-26-

11

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