SAFETY DATA SHEET
Issuing Date: 24Oct18

Revision Date: 24Oct18

1.

PRODUCT AND COMPANY IDENTIFICATION

1.1

Product Identifier
Product Name
Product Number(s)Other means of identificationRev. 01

SMRTbell® Express Template Prep Kit 2.0
100-938-900
This product is a kit box containing 17 reagent tubes.
Subcomponent Name

1.2

SDS PN: 101-692-200

Part ## tubes

Cap Color

DNA Prep Buffer

101-653-300

1GoldNAD

101-653-400

1Red

Enzyme Dilution Buffer

101-653-500

1PurpleNuclease-free Water

101-654-400

1WhiteDNA Prep Additive

101-653-600

1Light Purple

DNA Prep Enzyme

101-653-700

1Blue

DNA Damage Repair Mix v2101-653-800

1

Green

End Prep Mix

101-653-900

1Orange

Overhang Adapter v3101-654-000

1Light Green

Ligation Mix

101-654-100

1Yellow

Ligation Additive

101-654-200

1Light Blue

Ligation Enhancer

101-654-300

1Red

Sequencing Primer v4

101-654-600

1Light Blue

10X Primer Buffer v2001-560-849

1Blue

1X Elution Buffer

100-159-800

3WhiteRelevant Identified Uses of the Substance or Mixture and Uses Advised Against
Identified Use
Restrictions on Use

For use with the Pacific Biosciences PacBio® Sequel® system.
FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC
PROCEDURES.

1.3

Details of the Supplier of the Substance or Mixture
Supplier Name and Address Pacific Biosciences of CA, Inc.
1305 O’Brien Drive
Menlo Park, CA 94025
U.S.A
www.pacificbiosciences.com

1.4

Emergency Telephone Number

Supplier phone
Within USA & Canada
Outside USA and Canada+1 650-521-8000
Call CHEMTREC 1-800-424-9300 (reference CCN# 656805)
techsupport@pacb.com

2.

HAZARD(S) IDENTIFICATION

2.1

Classification of the substance or mixture
The kit is not a hazardous substance or mixture.1 Subcomponents are classified as follows.

1Classification in accordance with 29CFR1910 (OSHA HCS) and UN Globally Harmonized system of classification and labelling of chemicals

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Subcomponent Name

2.2

Part #Classification

DNA Prep Buffer

101-653-300

Not a hazardous substance or mixture.

NAD101-653-400

Not a hazardous substance or mixture.

Enzyme Dilution Buffer

101-653-500

Not a hazardous substance or mixture.

Nuclease-free Water

101-654-400Not a hazardous substance or mixture.

DNA Prep Additive

101-653-600

Not a hazardous substance or mixture.

DNA Prep Enzyme

101-653-700

Not a hazardous substance or mixture.

DNA Damage Repair Mix v2

101-653-800

Not a hazardous substance or mixture.

End Prep Mix

101-653-900

Not a hazardous substance or mixture.

Overhang Adapter v3

101-654-000

Not a hazardous substance or mixture.

Ligation Mix

101-654-100

Not a hazardous substance or mixture.

Ligation Additive

101-654-200

Not a hazardous substance or mixture.

Ligation Enhancer

101-654-300

Not a hazardous substance or mixture.

Sequencing Primer v4

101-654-600

Not a hazardous substance or mixture.

10X Primer Buffer v2001-560-849

Not a hazardous substance or mixture.

1X Elution Buffer

100-159-800

Not a hazardous substance or mixture.

GHS Label Elements and precautionary statements
Not a hazardous substance or mixture.

2.3

Hazards not otherwise classified (HNOC) or not covered by GHS
Subcomponent DNA Prep Enzyme PN# 101-653-700 contains BSA. Country of origin USA. The BSA in thissubcomponent has been granted an EDQM “Certificate of Suitability” from the European Directorate for theQuality of Medicine (# R1-CEP-2003-204-Rev00) and has been granted a USDA Certificate for Export of Bovine
Blood Plasma/Serum for Manufacture into Pharmaceutical Products.

3.

COMPOSITION / INFORMATION ON INGREDIENTS

3.1

Substances
Common Name and Synonyms

3.2

SMRTbell® Express Template Prep Kit 2.0

CAS Number

None

Other unique identifiers

None

Hazardous components
No ingredients are hazardous according to OSHA or GHS criteria.

4.

FIRST AID MEASURES

4.1

Description of First Aid Measures
General advice
If inhaled

If breathed in, move person into fresh air. If not breathing, give artificial respiration

In case of skin contact

Wash off with water.

In case of eye contact

Flush eyes with water.

If swallowed
4.2

Consult a physician. Show this safety data sheet to the physician.

Never give anything by mouth to an unconscious person. Rinse mouth with water.

Most important symptoms/effects, both acute and delayed
No data available. Refer to section 2.2 and section 11 for additional information.

4.2

Indication of any immediate medical attention and special treatment needed
No data available

5.

FIRE-FIGHTING MEASURES

5.1

Suitable Extinguishing Media

5.2

Special hazards arising from the substance or mixture

5.3

Advice for firefighters (special protective equipment or precautions)

Dry chemical, carbon dioxide, foam or water.
Combustion will produce oxides of carbon, nitrogen and sulfur.
Wear self-contained breathing apparatus for fire-fighting as necessary.
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6.

ACCIDENTAL RELEASE MEASURES

6.1

Personal precautions, protective equipment and emergency procedures
Avoid breathing vapors, mists or gas. For personal protection see section 8.0.

6.2

Environmental precautions
Avoid release to the environment. Report spills and releases as required to appropriate authorities.

6.3

Methods and materials for cleanup
Wear personal protective equipment, wipe up with paper towel (or similar), and contain in closed containers.

6.4

Reference to other sections
For disposal see section 13.

7.

HANDLING AND STORAGE

7.1

Precautions for safe handling

7.2

Conditions for safe storage, including any incompatibilities

Utilize standard good lab practices. Use in a well-ventilated area and wear standard PPE.
Keep containers tightly closed at the recommended storage temperature.

8.

EXPOSURE CONTROLS / PERSONAL PROTECTION

8.1

Control Parameters
Contains no substances with occupational exposure limit values.

8.2

Exposure Controls
Appropriate engineering controls:
General industrial hygiene practice. No special ventilation required for normal use
Personal Protective Equipment (PPE):
Eye/Face Protection
Skin and Body Protection
Respiratory Protection

Safety glasses
Latex or nitrile gloves; lab coat /apron
None required9.

PHYSICAL AND CHEMICAL PROPERTIES

9.1

Information on basic physical and chemical properties
Appearance
Odor
Odor ThresholdpH

Each reagent tube contains clear colorless liquid.
None
Not applicable
7.0-8.0

Melting point/freezing point

No data available.

Initial boiling point and boiling range

No data available

Flash point

No data available

Evaporation rate

No data available

Flammability (solid, gas)

No data available

Upper/lower flammability limit

No data available

Vapor pressure

No data available

Relative density

No data available

Solubility(ies)

No data available

Partition coefficient: n-octonal/water

No data available

Auto-ignition temperature

No data available

Decomposition temperature

No data available

Viscosity

No data available

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10.

STABILITY AND REACTIVITY
Reactivity
Chemical Stability

This product is not reactive under normal conditions of storage and use.
Stable under recommended storage conditions.

Possibility of Hazardous Reactions

No data availableConditions to Avoid

No data available

Incompatible Materials
Hazardous Decomposition Products

Avoid contact with strong oxidizers
No data available. In the event of fire see section 5.

11.

TOXICOLOGICAL INFORMATION

11.1

Information on likely routes of exposure

11.2

Symptoms related to the physical, chemical and toxicological characteristics

11.3

Delayed and immediate effects and also chronic effects from short and long-term exposure

The most likely route of exposure is via skin or eye contact. Exposure via inhalation or ingestion is less likely.
No data available

11.4

11.5

Eyes

No data available

Skin

No data available

Inhalation

No data available

Ingestion

No data available

Chronic Effects

No data available

Aggravated Medical Conditions

No data available

Interactions with other Chemicals

No data available

Numerical measures of toxicity
Acute toxicity

No data available

Skin corrosion/irritation

No data available

Serious eye damage/irritation

No data available

Respiratory or skin sensitization

No data available

Germ cell mutagenicity

No data available

Reproductive toxicity

No data available

Specific target organ toxicity

No data available

Carcinogenicity
No ingredients in this product are listed as carcinogens by ACGIH, IARC, NTP or OSHA.

12.

ECOLOGICAL INFORMATION
Ecotoxicity

No data available

Persistence and Degradability

No data available

Bioaccumulative Potential

No data available

Mobility in soil

No data available

Results of PBT and vPvB Assessment
Other adverse effects

13.

None Required
No data available

DISPOSAL CONSIDERATIONS
Dispose all waste in accordance with local, regional and national regulations.

14.

Product

See above

Contaminated Packaging

See above

US EPA Waste Number

No EPA ID number. Not regulated as a US federal hazardous waste. Notregulated under Title 22 as a California hazardous waste.

TRANSPORT INFORMATION
Transportation of this product is not regulated under ICAO, IMDG or US DOT.

15.

REGULATORY INFORMATION

15.1

USA Federal Regulations
SARA 302

No chemicals in this material are subject to the reporting requirements of SARA Title III, Section 302
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SARA 313
SARA 311/312
TSCA
15.2

This material does not contain any chemical components with known CAS numbers that exceed thethreshold reporting levels established by SARA Title III, Section 313
No SARA 311/312 hazards
Research use only

USA State Regulations
CA Prop 65

This product does not contain any chemicals known to the State of California to cause cancer oradverse reproductive health effects

16. OTHER INFORMATION
Prepared By

Pacific Biosciences of California, Inc.
Environment, Health and Safety
1305 O’Brien Drive
Menlo Park, CA 94025
U.S.A.
safety@pacb.com

FurtherInformation

The above information is believed to be correct but does not purport to be all inclusive and shall be
used only as a guide. The information in this document is based on the present state of ourknowledge and is applicable to the product with regard to appropriate safety precautions. It does not
represent any guarantee of the properties of the product. It is not a warranty or quality specification.
This information relates only to the specific material designated and may not be valid for use incombination with any other material or in any other process.
For Research Use Only. Not for use in diagnostic procedures. © Copyright 2018, Pacific Biosciencesof California, Inc. All right reserved. Information in this document is subject to change without notice.
Pacific Biosciences assumes no responsibility for any errors or omissions in this document. Certain
notices, terms, conditions and/or use restrictions may pertain to your use of Pacific Biosciences
products and/or third-party products. Please refer to the applicable Pacific Bioscience Terms andConditions of Sale and to the applicable license terms at http://www.pacb.com/legal-andtrademarks/product-license-and-use-restrictions/.
Pacific Biosciences, the Pacific Biosciences logo, PacBio, SMRT, SMRTbell, Iso-Seq, and Sequel
are trademarks of Pacific Biosciences. BluePippin and SageELF are trademarks of Sage Science.
NGS-go and NGSengine are trademarks of GenDx. FEMTO Pulse and Fragment Analyzer aretrademarks of Advanced Analytical Technologies. All other trademarks are the sole property of theirrespective owners.

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P/N: 101-648-100, Rev: 01
Governing Procedure: 101-647-900 WI, Creation of Product Safety Data Sheet Rev01