Detailed Rules of Contract in Preparation of Genetically Modified Mice and OtherServices in Laboratory Animal Resource Center, National University Corporation
University of Tsukuba
July 24, 2013
Detailed Departmental Rules No. 9, Faculty of Medicine	 

Detailed Rules of Contract in Preparation of Genetically Modified Mice and Other Services inLaboratory Animal Resource Center, National University Corporation University of Tsukuba	 	 (Purport)
Article 1: These Detailed Departmental Rules shall stipulate the matters required for the preparationand supply of genetically modified mice (hereinafter referred to as “preparation”) as contract
services by Laboratory Animal Resource Center (hereinafter referred to as “Center”) in accordancewith the stipulations in Detailed Rules of Laboratory Animal Resource Center, National University
Corporation University of Tsukuba (Detailed Departmental Rules No.

, Faculty of Medicine, 2013),

Article 6.	 
(Preparation)
Article 2: Preparation of genetically modified mice conducted as contract services by the Center
shall refer to the followings:(1) Preparation of transgenic mice by use of submitted DNA samples(2) Preparation of chimeric mice by use of submitted ES cells(3) Preparation of mutant ES cells by use of submitted gene-targeting vectors(4) Preparation of gene-targeting vectors	 
(Consignment of preparation)
Article 3: Those who desire to consign preparation of genetically modified mice (hereinafter referredto as “Consignors”) shall submit the Form for Preparation of Genetically Modified Mice which isAppended Forms 1 and 3 in the cases of Numbers 1/2 and Number 3 referred to in the preceding
Article, respectively, to the director of the Center (hereinafter referred to as “Director”). Consignors
for the service of Preparation of Gene-Targeting Vectors shall submit Appended Form 5 in the caseof Number 4 referred to in the said Article to the Director.

2. Upon contract of Preparation of Genetically Modified Mice, Director shall notify Consignor byuse of the Letter of Notice of Contract Decision for Preparation of Genetically Modified Mice,
which is Appended Form 3. Upon contract of Preparation of Vectors for Genetic Transformation,
Director shall notify Consignor by use of the Letter of Notice of Contract Decision for Preparationof Vectors for Genetic Transformation, which is Appended Form 6.	 
(Payment of fees)
Article 4: Consignor shall pay the fee stipulated in the appended table in advance upon receipt of thenotice referred to in the preceding Article. However, this is not applicable to the National
Government, National University Corporations, Inter-University Research Institute Corporations,
Independent Administrative Institutions, and local public organizations.
2. Paid fees are not refundable.	 
(Supply)
Article 5: Director shall supply Consignor with the product of Preparation of Genetically Modified
Mice upon completion, with the Cover Letter for Genetically Modified Mice which is Appended
Form 4. Director shall supply Consignor with the product of Preparation of Vectors for Genetic
Transformation upon completion, with the Cover Letter for Vectors for Genetic Transformation,
which is Appended Form 7.	 
(Miscellaneous rules)
Article 6: Director shall separately stipulate matters required for Preparation of Genetically Modified
Mice that are not stipulated in these Detailed Departmental Rules.	 
Supplementary rules
1. These Detailed Departmental Rules shall be put into force on July 24, 2013, and applied from
April 1, 2013.
2. The Detailed Rules of Contract in Preparation of Genetically Modified Mice in Laboratory
Animal Research Center, National University Corporation Tsukuba University (Detained
Departmental Rules No. 3, Graduate School of Comprehensive Human Sciences, March 18, 2005)
shall be repealed.