HEALTH - FOODSLEEP WELL AND LIVE BETTERRELISSA™

MELISSA PHYTOSOME®

Please note this documentation is available for various countries all over the world and hence it may containstatements or product classification not applicable to your country. The claims made are in reference toingredients only, hence they do not refer to finished products and they may not comply with Regulation ECn. 1924/2006. The marketer of any finished product containing any ingredient is responsible for assuringthat the destination of the product and the claims made for the finished product are lawful and complywith all applicable laws and regulations of the country or countries in which the product is to be sold.

TRADEMARKSRELISSA™ is a trademark of Indena S.p.A.
and its logo and usage guidelines are available
from Indena.
DID YOU KNOW?
The scientific name Melissa officinalis L.
clearly reveals a direct ancient connection
with bees.
The blooming plant attracts scores of bees,
which feed on the tiny white flowers, and thegenus name Melissa is in fact derived fromthe Greek word for “bee”.
References
Indena internal data
Shakeri, F. et al., Journal of ethnopharmacology 188 (2016): 204-228
3Swiader, J. Appl. Bot. Food Qual 92 (2019): 327-335.
4
European commission Monography – Melissa Officinalis
5ESCOP - Melissa Officinalis
6
WHO Monography - Folium Melissae
7Thompson RS et al. Front Behav Neurosci 2017
8Dalile B. et al. Nat Rev Gastroenterol Hepatol 20199
Indena internal data
10
Bano A, et al. (2023) Front. Pharmacol. 14:1250560. doi: 10.3389/fphar.2023.1250560
11
Rondanelli M. et al., Journal of Food Science and Nutrition Research. 7 (2024): 125-130.
12DPR 0313 - 05/2022*07/2024

Not to mention, it’s made by Indena with a circular processthat starts with organic Melissa officinalis grown in Europe
and dried with the help of solar energy, and ends withsoil improver instead of waste. All made with strong
commitment to sustainability, in a certified ISO 14001 andISO 45001 plant where CO2 emissions are reduced, theenergy transition is underway, and occupational health andsafety are a priority.
Clinical evidences confirms its supportive action in balancing
moods and contrasting stress generated during the day, tocreate the conditions for a more serene life 24/7.2-6,10
Furthermore, its effectiveness has now been proven by thelatest scientific evidence on humans also at lower dosages,
proven its effectiveness in enhancing sleep quality, mentalwellbeing, and overall quality of life even when reducing thedaily supplementation from 400 to 200 mg.11
This makes RELISSA™ your new ally for relaxation andpeaceful sleep: proved by science and approved by nature.
RELISSA™ is formulated with Indena Phytosome®
technology to allow a better dispersion in gastrointestinal
fluids, optimizing bioabsorption profile and performances.1
Lately, there has been an increased interest in how themicrobiome may influence our wellbeing, especially in therealm of mood and sleep.

Lactobacillus rhamnosus - a bacteria able to colonize thegastrointestinal tract - has been proven able to improvenight rest and rapid eye movement (REM) sleep7, thanks
to a positive influence over short-chain fatty acids (SCFAs)
controlling the expression of genes responsible for sleepwake rhythms.8
RELISSA™ has shown no negative interactions with
Lactobacillius rhamnosus, thus safeguarding its beneficial
effect.9

trademarks of Indena S.p.A. © 2024, Indena S.p.A. Italy

RECOMMENDED USE AND DOSERELISSA™ is a light brown powder for use innutritional supplements.
Recommended dose: 200-400 mg/day

Indena’s RELISSA™ positively impacts the amount andquality of sleep, leveraging Indena Phytosome® technology
to optimize the bioaccessibility of Melissa officinalis in theintestinal tract.

,SPECIFICATIONSRELISSA™ is standardized to contain:≥17% ≤ 23% of hydroxycinnamic acids byHPLC.

WHAT MAKES RELISSA™ UNIQUE?

® TM

WHAT IS RELISSA™?
RELISSA™ is not the usual lemon balm
ingredient: it is a standardized Melissa
officinalis leaves extract with high content
of hydroxycinnamic and rosmarinic acid,blended with an innovative formulativetechnology.1

RELISSA™ can also be formulated also in gummies, anincreasingly popular solution on the market.

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