RAP

RIKEN Center for Advanced Photonics
2024 - 2025

RIKEN Center for Advanced Photonics
2-1, Hirosawa, Wako, Saitama, 351-0198, Japan
https://rap.riken.jp/en/
RIKEN 2024-013

Opening up new horizons with photonics
RIKEN Center for Advanced Photonics (RAP) is helping

ever seen before. Being able to see objects helps us toto realize the dream of making the invisible visible.

understand and manipulate them.

As one example, stroboscopes, which allow us to see

The work of the Center for Advanced Photonics

high-speed phenomena by pulsing light in a shortfocuses not simply on making discoveries that will be

duration, cannot catch the movements of molecules orrecognized by the research community, but rather on

atoms because they simply move too fast. However,contributing to society by developing practical

thanks to research in photonics, lasers developed toapplications of advanced photonics.

generate pulses at even shorter duration such as 10-15

second (1 femtosecond) or 10-18 second (1 attosecond)
now allow us to see the movements of electrons inatoms or molecules.
Electron microscopy makes it possible for us toobserve objects at extremely high resolution. However
it requires the specimen to be put in a vacuum, making
it impossible to see living cells. Using an optical
microscope opens up that possibility. It was generally

Just as our social infrastructure was transformed by
the steam engine in the 19th century and by electronics
in the 20th century, photonics technology will lead toanother transformation of social infrastructure in thecurrent century.
The possibilities opened by photonics are expanding.
We are still in the very early stage of this new
revolution.

thought that it was impossible to picture objects
smaller than half of the wavelength of light in the visible

expanding the horizons of photon science.

spectrum, but the super-resolution microscopes break

Quantum Optoelectronics Research Team ................................ 07

Team Leader Yuichiro Kato

Ultrafast Coherent Soft X-ray Photonics Research Team ......... 08
Ultrashort Electron Beam Science RIKEN Hakubi Research Team ...... 09

RIKEN Hakubi Team Leader Yuya Morimoto

Subwavelength Photonics Research GroupLive Cell Super-Resolution Imaging Research Team ................ 10

Deputy Team Leader Akihiko Nakano

Image Processing Research Team ............................................. 12

destroying a sample. Terahertz wave makes thisInnovative Photon Manipulation Research Team ....................... 13

possible. Terahertz wave, which has been called theTeam Leader Takuo Tanaka“unexplored spectrum of light,” is now moving into the

Advanced Laser Processing Research Team ............................. 14

application phase thanks to advances in light sources

Team Leader Koji Sugioka

and detectors.

Digital Twin for Light-Matter Interaction RIKEN ECL Research Team .. 15

RIKEN ECL Team Leader Shutaro Tani

In addition, applications in the field of photonics areneutron source, all making visible what nobody has

Space-Time Engineering Research Team .................................. 06

Team Leader Hidetoshi Katori

Team Leader Hideo Yokota

device or look for contamination in foods without

inspection of concrete structures with a compact

Ultrafast Spectroscopy Research Team ..................................... 05

Team Leader Tahei Tahara

Team Leader Atsushi Miyawaki

We sometimes need to inspect the inner structure of aultraprecision optical lattice clocks, nondestructive

Attosecond Science Research Team .......................................... 04

Team Leader Katsumi Midorikawa

Biotechnological Optics Research Team ................................... 11

this barrier and allow us to access the nanoworld.

with metamaterials, relativistic geodesy using

Extreme Photonics Research GroupTeam Leader Eiji J. Takahashi

RIKEN Center for Advanced Photonics is committed to

expanding in areas such as light wave manipulation

RIKEN Center
for Advanced Photonics

Center Director

Katsumi Midorikawa

Terahertz-wave Research Group
Tera-Photonics Research Team ................................................. 17

Team Leader Hiroaki Minamide

Terahertz Sensing and Imaging Research Team ....................... 18

Team Leader Chiko Otani

Terahertz Quantum Device Research Team ............................... 19

Team Leader Hideki Hirayama

Advanced Photonics Technology Development Group
Photonics Control Technology Team .......................................... 20

Team Leader Satoshi Wada

Ultrahigh Precision Optics Technology Team ............................ 21

Team Leader Yutaka Yamagata

Neutron Beam Technology Team ................................................ 22

Team Leader Yoshie Otake

Advanced Manufacturing Support Team ................................... 23

Team Leader Yutaka Yamagata

Office of the Center Director Director Akihiko Nakano

Extreme Photonics Research Group

Extreme Photonics Research Group

Attosecond Science Research Team
Team Leader

Katsumi Midorikawa

Ultrafast Spectroscopy Research Team
Team Leader

Dr.Eng.

Tahei Tahara

D.Sci.

▲

Fields▲FieldsExpanding the horizon of optical scienceby attosecond photonics

Elucidating complex molecular dynamics
with femtosecond light

Recent advances in femtosecond high-intensity laser technology have made it possible

Most of the phenomena in nature are realized by the dynamic behavior of molecules.

to generate intense ultrashort pulses of a few cycles and control their phases. As a

Among them, chemical reactions are critically important, which dynamically cause the▲result, research on the nonlinear interaction between light and atoms/molecules hascleavage and formation of chemical bonds and alter the nuclear arrangement within the▲

1. Lin, Y-C., Midorikawa, K., Nabekawa, Y.:“Wavefront control of subcycle vortex pulses via
carrier-envelop-phase tailoring” , Light: Sci. &Appl. 12, 279 (2023).

progressed dramatically, and new research areas such as high-order harmonic

molecules. Even non-reactive molecules are vibrating, which provides rich information

generation, Coulomb explosion, and high-energy X-ray/particle generation have been

about the molecular properties. Because the timescale of such molecular motion isborn. High-order harmonic generation can provide intense attosecond pulses that cause

femtosecond (one quadrillionth of a second), femtosecond spectroscopy is essential

nonlinear optical phenomena in the extreme ultraviolet to soft X-ray region. The

for elucidating chemical phenomena. Our team investigates the dynamics of molecules

1. Kuramochi, H., Tsutsumi, T., Saita, K., Wei, Z.,
Osawa, M., Kumar, P., Liu, L., Takeuchi, S.,
Taketsugu T., Tahara, T.: “Ultrafast Raman
observation of the perpendicular intermediate
phantom state of stilbene photoisomerization” ,Nat. Chem. 16, 22 (2024).

generation of high-order harmonics is also a unique physical phenomenon that makes itfrom fundamental to complex systems, as well as the molecules in special

possible to observe ultrafast phenomena occurring in atoms and molecules on anenvironments such as interfaces. We extend the frontier of molecular science throughattosecond time scale. Our team is researching extreme nonlinear optics andthe development and use of advanced spectroscopic methods.

Interdisciplinary Science and Engineering,Engineering, Physics, Chemistry▲

Keywords▲

Keywords

Chemistry, Physics, Biology / Biochemistry

Attosecond Science, Ultrafast Lasers, Strong Field
Physics, Nonlinear Optics, Multiphoton Microscopy

Publications

2. Midorikawa, K.: “Progress on table-top isolated
attosecond light sources” , Nature Photonics 16,
267 (2022).
3. Matsubara, T., Fukahori, S., Lötstedt, E.,
Nabekawa, Y., Yamanouchi, K., and Midorikawa,
K.: “300 attosecond response of acetylene in
two-photon ionization/dissociation processes” ,Optica 8, 1075 (2021).
4. Lin, Y-C., Nabekawa, Y., and Midorikawa, K.:“Optical parametric amplification of sub-cycle
shortwave infrared pulses” , Nat. Commun. 11,3413 (2020).

attosecond

atomic/molecular dynamics using a high-intensity attosecond pulse lightsource.

Ultrafast spectroscopy, Nonlinear spectroscopy,
Single molecule spectroscopy,
Dynamics, Interface

Publications

2. Sung, W., Inoue, K., Nihonyanagi, S., Tahara, T.:“Unified picture of vibrational relaxation of OH
stretch at the air/water interface” , Nat. Commun.
15, 1258 (2024).
3. Kumar, P. Kuramochi, H. Takeuchi, S. Tahara, T.:"Photoexcited plasmon-driven ultrafast dynamics
of the adsorbate probed by femtosecond
time-resolved surface-enhanced time-domain
Raman spectroscopy", J. Phys. Chem. Lett. 14,2845 (2023).
4. Chang, C., Kuramochi, M., Singh, M.,
Abe-Yoshizumi, R., Tsukuda, T., Kandori, H., andTahara, T.: “A unified view on varied ultrafast
dynamics of the primary process in microbial
rhodopsins” , Angew. Chem. Int. Ed. 61,
e202111930 (2022).

5. Xue, B., Tamaru, Y., Yuan, H., Lan, P., Mücke, O. D.,
Suda, A., Midorikawa, K., and Takahashi, E. J.:“Fully stabilized multi-TW optical waveform
synthesizer: Toward gigawatt isolated attosecond
pulses” , Science Advances 6, eaay2820 (2020).

5. Kusaka, R., Nihonyanagi, S., and Tahara, T.: “Thephotochemical reaction of phenol becomes
ultrafast at the air–water interface” , Nat. Chem.
13, 306 (2021).

▲

MemberYasuo Nabekawa / Yutaka Nagata /Keisuke Isobe / Tomoya Okino /▲Takashige Fujiwara / Yu-Chieh Lin /Kaoru Yamazaki / Tohru Kobayashi /MemberKunihiko Ishii / Satoshi Nihonyanagi /Takiko Wakabayashi

Korenobu Matsuzaki / Jan Georg Borter

Autocorrelation waveform of attosecond pulse train
measured with carbon ion yield from acetylene
Coherent nuclear motion of the chromophore of a protein in reaction

04

05

Extreme Photonics Research Group

Extreme Photonics Research Group

Attosecond Science Research Team
Team Leader

Katsumi Midorikawa

Ultrafast Spectroscopy Research Team
Team Leader

Dr.Eng.

Tahei Tahara

D.Sci.

▲

Fields▲FieldsExpanding the horizon of optical scienceby attosecond photonics

Elucidating complex molecular dynamics
with femtosecond light

Recent advances in femtosecond high-intensity laser technology have made it possible

Most of the phenomena in nature are realized by the dynamic behavior of molecules.

to generate intense ultrashort pulses of a few cycles and control their phases. As a

Among them, chemical reactions are critically important, which dynamically cause the▲result, research on the nonlinear interaction between light and atoms/molecules hascleavage and formation of chemical bonds and alter the nuclear arrangement within the▲

1. Lin, Y-C., Midorikawa, K., Nabekawa, Y.:“Wavefront control of subcycle vortex pulses via
carrier-envelop-phase tailoring” , Light: Sci. &Appl. 12, 279 (2023).

progressed dramatically, and new research areas such as high-order harmonic

molecules. Even non-reactive molecules are vibrating, which provides rich information

generation, Coulomb explosion, and high-energy X-ray/particle generation have been

about the molecular properties. Because the timescale of such molecular motion isborn. High-order harmonic generation can provide intense attosecond pulses that cause

femtosecond (one quadrillionth of a second), femtosecond spectroscopy is essential

nonlinear optical phenomena in the extreme ultraviolet to soft X-ray region. The

for elucidating chemical phenomena. Our team investigates the dynamics of molecules

1. Kuramochi, H., Tsutsumi, T., Saita, K., Wei, Z.,
Osawa, M., Kumar, P., Liu, L., Takeuchi, S.,
Taketsugu T., Tahara, T.: “Ultrafast Raman
observation of the perpendicular intermediate
phantom state of stilbene photoisomerization” ,Nat. Chem. 16, 22 (2024).

generation of high-order harmonics is also a unique physical phenomenon that makes itfrom fundamental to complex systems, as well as the molecules in special

possible to observe ultrafast phenomena occurring in atoms and molecules on anenvironments such as interfaces. We extend the frontier of molecular science throughattosecond time scale. Our team is researching extreme nonlinear optics andthe development and use of advanced spectroscopic methods.

Interdisciplinary Science and Engineering,Engineering, Physics, Chemistry▲

Keywords▲

Keywords

Chemistry, Physics, Biology / Biochemistry

Attosecond Science, Ultrafast Lasers, Strong Field
Physics, Nonlinear Optics, Multiphoton Microscopy

Publications

2. Midorikawa, K.: “Progress on table-top isolated
attosecond light sources” , Nature Photonics 16,
267 (2022).
3. Matsubara, T., Fukahori, S., Lötstedt, E.,
Nabekawa, Y., Yamanouchi, K., and Midorikawa,
K.: “300 attosecond response of acetylene in
two-photon ionization/dissociation processes” ,Optica 8, 1075 (2021).
4. Lin, Y-C., Nabekawa, Y., and Midorikawa, K.:“Optical parametric amplification of sub-cycle
shortwave infrared pulses” , Nat. Commun. 11,3413 (2020).

attosecond

atomic/molecular dynamics using a high-intensity attosecond pulse lightsource.

Ultrafast spectroscopy, Nonlinear spectroscopy,
Single molecule spectroscopy,
Dynamics, Interface

Publications

2. Sung, W., Inoue, K., Nihonyanagi, S., Tahara, T.:“Unified picture of vibrational relaxation of OH
stretch at the air/water interface” , Nat. Commun.
15, 1258 (2024).
3. Kumar, P. Kuramochi, H. Takeuchi, S. Tahara, T.:"Photoexcited plasmon-driven ultrafast dynamics
of the adsorbate probed by femtosecond
time-resolved surface-enhanced time-domain
Raman spectroscopy", J. Phys. Chem. Lett. 14,2845 (2023).
4. Chang, C., Kuramochi, M., Singh, M.,
Abe-Yoshizumi, R., Tsukuda, T., Kandori, H., andTahara, T.: “A unified view on varied ultrafast
dynamics of the primary process in microbial
rhodopsins” , Angew. Chem. Int. Ed. 61,
e202111930 (2022).

5. Xue, B., Tamaru, Y., Yuan, H., Lan, P., Mücke, O. D.,
Suda, A., Midorikawa, K., and Takahashi, E. J.:“Fully stabilized multi-TW optical waveform
synthesizer: Toward gigawatt isolated attosecond
pulses” , Science Advances 6, eaay2820 (2020).

5. Kusaka, R., Nihonyanagi, S., and Tahara, T.: “Thephotochemical reaction of phenol becomes
ultrafast at the air–water interface” , Nat. Chem.
13, 306 (2021).

▲

MemberYasuo Nabekawa / Yutaka Nagata /Keisuke Isobe / Tomoya Okino /▲Takashige Fujiwara / Yu-Chieh Lin /Kaoru Yamazaki / Tohru Kobayashi /MemberKunihiko Ishii / Satoshi Nihonyanagi /Takiko Wakabayashi

Korenobu Matsuzaki / Jan Georg Borter

Autocorrelation waveform of attosecond pulse train
measured with carbon ion yield from acetylene
Coherent nuclear motion of the chromophore of a protein in reaction

04

05

Extreme Photonics Research Group

Extreme Photonics Research GroupSpace-Time Engineering Research Team
Team Leader

Hidetoshi Katori

Quantum Optoelectronics Research Team
Team Leader

D.Eng.

Yuichiro Kato

Ph.D.

Interdisciplinary Science and Engineering,Engineering

Relativistic Space-Time Engineeringwith Ultra Precise Atomic Clocks

Towards optoelectronic devices that utilize
the quantum nature of electrons and photons

Clocks have served as a tool to share time, based on universal periodic phenomena;

Advances in device fabrication techniques have enabled integration of individual

humankind relied upon the rotation of the earth from antiquity. The radiation from an atom

nanomaterials, where single electrons and single photons could be addressed. We▲

Keywords▲

Fields▲Fieldsprovides us with far more accurate periodicity. The state-of-the-art atomic clocks sense

exploit state-of-the-art nanofabrication technologies to develop and engineer

1. Takamoto, M., Ushijima, I., Ohmae, N., Yahagi, T.,
Kokado, K., Shinkai, H., and Katori, H.: "Test of generalrelativity by a pair of transportable optical latticeclocks", Nat. Photonics 14, 411-415 (2020).

the relativistic space-time curved by gravity, which reveal the difficulty of sharing time withoptoelectronic devices with novel functionalities that can only be achieved by utilizing

others. Moreover, such clocks may be used to investigate the constancy of fundamental

the quantum nature of electrons and photons at the nanoscale. We investigate devices

2. Ushijima, I., Takamoto, M., and Katori, H.: “Operational
magic intensity for Sr optical lattice clocks” , Phys.
Rev. Lett. 121, 263202 (2018).

constants, where the foundation of the atomic clocks is anchored.

that would allow for control over the interactions between electrons and photons at the

Optical lattice clocks raised the possibility of ultra-stable and accurate timekeeping by

quantum mechanical level, which would lead to quantum photon sources andapplying the "magic wavelength" protocol on optical lattices. Since the proposal of the

optical-to-electrical quantum interfaces.

3. Takano, T., Takamoto, M., Ushijima, I., Ohmae, N.,
Akatsuka, T., Yamaguchi, A., Kuroishi, Y., Munekane, H.,
Miyahara, B., and Katori, H.: “Geopotential
measurements with synchronously linked opticallattice clocks” , Nat. Photonics 10, 662-666 (2016).
4. Yamanaka, K., Ohmae, N., Ushijima, I., Takamoto, M.,
and Katori, H.: “Frequency ratio of 199Hg and 87Sr
optical lattice clocks beyond the SI limit” , Phys. Rev.
Lett. 114, 230801 (2015).
5. Ushijima, I., Takamoto, M., Das, M., Ohkubo, T., andKatori, H.: “Cryogenic optical lattice clocks” , Nat.
Photonics 9, 185-189 (2015).

the world, and the clocks are surpassing the uncertainty of the current SI second, becoming

Our team develops highly precise and transportable optical lattice clocks capable oflong time operation by introducing advanced techniques in the field of atomic physics

Masao Takamoto / Atsushi Yamaguchi / Shinji Itoultraprecise atomic clock, which may be taken out into the field, will function as a

1. Fang, N., Chang, Y. R., Fujii, S., Yamashita, D.,
Maruyama, M., Gao, Y., Fong, C. F., Kozawa D.,
Otsuka, K., Nagashio, K., Okada, S., Kato, Y. K.:“Room-temperature quantum emission frominterface excitons in mixed-dimensional
heterostructures,” Nature Commun. 15, 2871
(2024).
2. Fujii, S., Fang, N., Yamashita, D., Kozawa D., Fong,
C. F., Kato, Y. K.: “van der Waals decoration ofultra-high-Q silica microcavities for χ(2)-χ(3) hybrid
nonlinear photonics,” Nano Lett. 24, 4209 (2024).

4. Kozawa, D., Wu, X., Ishii, A., Fortner, J., Otsuka, K.,
Xiang, R., Inoue, T., Maruyama, S., Wang, Y., Kato, Y.
K.: “Formation of organic color centers in
air-suspended carbon nanotubes using
vapor-phase reaction,” Nature Commun. 13, 2814
(2022).

and quantum optics; we thus explore applications of "space-time engineering" that fully
utilize the novel time resource provided by such clocks. For example, a transportable

Publications

3. Fang, N., Chang, Y. R., Yamashita, D., Fujii, S.,
Maruyama, M., Gao, Y., Fong, C. F., Otsuka, K.,
Nagashio, K., Okada, S., Kato, Y. K.: “Resonant
exciton transfer in mixed-dimensional
heterostructures for overcoming dimensional
restrictions in optical processes,” Nature
Commun. 14, 8152 (2023).

one of the most promising candidates for the future redefinition of the second.

▲

Memberscheme in 2001, the optical lattice clocks are being developed by more than 20 groups in

Optoelectronics, Quantum devices, Nanoscale
devices, Carbon nanotubes, Photonic crystals▲▲

Publications

Keywords▲

Quantum electronics, Atomic clock, Quantum
metrology, Optical lattice clock, Relativistic geodesy

Engineering, Physics, Chemistry,
Interdisciplinary Science and Engineering

gravitational potential meter. We experimentally investigate the impact of such

5. Otsuka, K., Fang, N., Yamashita, D., Taniguchi, T.,
Watanabe, K., and Kato, Y. K.: “Deterministictransfer of optical-quality carbon nanotubes foratomically defined technology,” Nature Commun.
12, 3138 (2021).

relativistic geodesy and new roles for clocks in the future.

▲MemberHiroyuki Nishidome / Mengyue Wang /Ufuk Erkilic / Clement Deleau
Scanning electron micrograph of a suspended carbon nanotube field effect transistor

Remote frequency comparison of optical lattice clocks between RIKEN and the Universityof Tokyo (UTokyo) reveals their different tick rates as predicted by general relativity.

06

07

Extreme Photonics Research Group

Extreme Photonics Research GroupSpace-Time Engineering Research Team
Team Leader

Hidetoshi Katori

Quantum Optoelectronics Research Team
Team Leader

D.Eng.

Yuichiro Kato

Ph.D.

Interdisciplinary Science and Engineering,Engineering

Relativistic Space-Time Engineeringwith Ultra Precise Atomic Clocks

Towards optoelectronic devices that utilize
the quantum nature of electrons and photons

Clocks have served as a tool to share time, based on universal periodic phenomena;

Advances in device fabrication techniques have enabled integration of individual

humankind relied upon the rotation of the earth from antiquity. The radiation from an atom

nanomaterials, where single electrons and single photons could be addressed. We▲

Keywords▲

Fields▲Fieldsprovides us with far more accurate periodicity. The state-of-the-art atomic clocks sense

exploit state-of-the-art nanofabrication technologies to develop and engineer

1. Takamoto, M., Ushijima, I., Ohmae, N., Yahagi, T.,
Kokado, K., Shinkai, H., and Katori, H.: "Test of generalrelativity by a pair of transportable optical latticeclocks", Nat. Photonics 14, 411-415 (2020).

the relativistic space-time curved by gravity, which reveal the difficulty of sharing time withoptoelectronic devices with novel functionalities that can only be achieved by utilizing

others. Moreover, such clocks may be used to investigate the constancy of fundamental

the quantum nature of electrons and photons at the nanoscale. We investigate devices

2. Ushijima, I., Takamoto, M., and Katori, H.: “Operational
magic intensity for Sr optical lattice clocks” , Phys.
Rev. Lett. 121, 263202 (2018).

constants, where the foundation of the atomic clocks is anchored.

that would allow for control over the interactions between electrons and photons at the

Optical lattice clocks raised the possibility of ultra-stable and accurate timekeeping by

quantum mechanical level, which would lead to quantum photon sources andapplying the "magic wavelength" protocol on optical lattices. Since the proposal of the

optical-to-electrical quantum interfaces.

3. Takano, T., Takamoto, M., Ushijima, I., Ohmae, N.,
Akatsuka, T., Yamaguchi, A., Kuroishi, Y., Munekane, H.,
Miyahara, B., and Katori, H.: “Geopotential
measurements with synchronously linked opticallattice clocks” , Nat. Photonics 10, 662-666 (2016).
4. Yamanaka, K., Ohmae, N., Ushijima, I., Takamoto, M.,
and Katori, H.: “Frequency ratio of 199Hg and 87Sr
optical lattice clocks beyond the SI limit” , Phys. Rev.
Lett. 114, 230801 (2015).
5. Ushijima, I., Takamoto, M., Das, M., Ohkubo, T., andKatori, H.: “Cryogenic optical lattice clocks” , Nat.
Photonics 9, 185-189 (2015).

the world, and the clocks are surpassing the uncertainty of the current SI second, becoming

Our team develops highly precise and transportable optical lattice clocks capable oflong time operation by introducing advanced techniques in the field of atomic physics

Masao Takamoto / Atsushi Yamaguchi / Shinji Itoultraprecise atomic clock, which may be taken out into the field, will function as a

1. Fang, N., Chang, Y. R., Fujii, S., Yamashita, D.,
Maruyama, M., Gao, Y., Fong, C. F., Kozawa D.,
Otsuka, K., Nagashio, K., Okada, S., Kato, Y. K.:“Room-temperature quantum emission frominterface excitons in mixed-dimensional
heterostructures,” Nature Commun. 15, 2871
(2024).
2. Fujii, S., Fang, N., Yamashita, D., Kozawa D., Fong,
C. F., Kato, Y. K.: “van der Waals decoration ofultra-high-Q silica microcavities for χ(2)-χ(3) hybrid
nonlinear photonics,” Nano Lett. 24, 4209 (2024).

4. Kozawa, D., Wu, X., Ishii, A., Fortner, J., Otsuka, K.,
Xiang, R., Inoue, T., Maruyama, S., Wang, Y., Kato, Y.
K.: “Formation of organic color centers in
air-suspended carbon nanotubes using
vapor-phase reaction,” Nature Commun. 13, 2814
(2022).

and quantum optics; we thus explore applications of "space-time engineering" that fully
utilize the novel time resource provided by such clocks. For example, a transportable

Publications

3. Fang, N., Chang, Y. R., Yamashita, D., Fujii, S.,
Maruyama, M., Gao, Y., Fong, C. F., Otsuka, K.,
Nagashio, K., Okada, S., Kato, Y. K.: “Resonant
exciton transfer in mixed-dimensional
heterostructures for overcoming dimensional
restrictions in optical processes,” Nature
Commun. 14, 8152 (2023).

one of the most promising candidates for the future redefinition of the second.

▲

Memberscheme in 2001, the optical lattice clocks are being developed by more than 20 groups in

Optoelectronics, Quantum devices, Nanoscale
devices, Carbon nanotubes, Photonic crystals▲▲

Publications

Keywords▲

Quantum electronics, Atomic clock, Quantum
metrology, Optical lattice clock, Relativistic geodesy

Engineering, Physics, Chemistry,
Interdisciplinary Science and Engineering

gravitational potential meter. We experimentally investigate the impact of such

5. Otsuka, K., Fang, N., Yamashita, D., Taniguchi, T.,
Watanabe, K., and Kato, Y. K.: “Deterministictransfer of optical-quality carbon nanotubes foratomically defined technology,” Nature Commun.
12, 3138 (2021).

relativistic geodesy and new roles for clocks in the future.

▲MemberHiroyuki Nishidome / Mengyue Wang /Ufuk Erkilic / Clement Deleau
Scanning electron micrograph of a suspended carbon nanotube field effect transistor

Remote frequency comparison of optical lattice clocks between RIKEN and the Universityof Tokyo (UTokyo) reveals their different tick rates as predicted by general relativity.

06

07

Extreme Photonics Research Group

Extreme Photonics Research Group

Ultrafast Coherent Soft X-ray Photonics Research Team
Team Leader

Eiji J. Takahashi

Ultrashort Electron Beam Science RIKEN Hakubi Research TeamRIKEN Hakubi Team Leader Yuya Morimoto Ph.D.

D.Eng.

Interdisciplinary Science and Engineering,Engineering, Complex systems

Creating novel ultrafast soft x-ray sources
using the extreme nature of laserSpace-time imaging of the initial steps ofchemical reactions with ultrashort electron beams

Laser is the ultimate light source created by mankind, and it has become an indispensable

Electron beams are used for examples in electron microscopy and electron-beam

tool for our social life. In this laboratory, our main goal is to create an unexplored ultrafast

lithography, where high spatial resolution is required. By using state-of-the-art laser andlaser by using the extreme nature of laser such as ultrashort pulse, super broadband, highelectron-beam technologies, we control the temporal structure of an electron beam withpower, and so on. Specifically, we are developing a high-power a few-cycle laser source,

ultimate attosecond resolution and apply the controlled electron beams for imaging andand using it to develop novel laser source with full coherence in the soft x-ray region and acontrolling ultrafast chemical reactions. We explore the atomic-scale dynamics ofpulse width of attosecond region. We extend the frontier of laser science through theelectrons in a material which is the initial step of most photochemical reactions.

Chemistry, Physics,
Interdisciplinary Science and Engineering,Engineering▲

Keywords▲

Fields▲Fields

▲

1. Lu, X., and Takahashi, E.J.: “Dual-chirped opticalparametric amplification of high-energy single-cycle
laser pulses” , Nature Photonics 18, 99-106 (2024).
2. Bing, X., Tamaru, Y., Fu, Y., Yuan, H., Lan, P., Mücke,O.D., Suda, A., Midorikawa, K., and Takahashi, E.J.:“Gigawatt-class, tabletop, isolated-attosecond-pulse
light source” , Optica 9, 360-363 (2022).

development of novel laser sources.

3. Lu, X., Bing, X., Ishii, N., Itatani, J., Midorikawa, K., andTakahashi, E.J.: “100-mJ class, sub-two-cycle,
carrier-envelope phase-stable dual-chirped opticalparametric amplification” , Opt Lett 47, 3371-3374(2022).

Ultrashort electron beam, Electron beam imaging,
Nonlinear optics, Attosecond science,
Atomic collisions

Publications▲

Publications

Keywords▲

High-power single-cycle laser, Attosecond laser,
MIR laser, Coherent soft x-ray, Strong-field physics

1. Morimoto, Y.: "Attosecond electron-beamtechnology: a review of recent progress” ,Microscopy 72, 2-17 (2023).
2. Morimoto, Y., Shinohara, Y., Tani, M., Chen, B.H.,
Ishikawa, K.L., and Baum, P.: “Asymmetric
single-cycle control of valence electron motion inpolar chemical bonds” , Optica 8, 382 (2021).
3. Morimoto, Y., Hommelhoff, P., and Madsen, L.B.:“Coherent scattering of an optically-modulated
electron beam by atoms” , Phys. Rev. A 103,
043110 (2021).
4. Morimoto, Y., and Baum, P.: “Single-Cycle OpticalControl of Beam Electrons” , Phys. Rev. Lett. 125,
193202 (2020).

4. Bing, X., Tamaru, Y., Fu, Y., Yuan, H., Lan, P., Mücke,O.D., Suda, A., Midorikawa, K., and Takahashi, E.J.: “ACustom-Tailored Multi-TW Optical Electric Field for
Gigawatt Soft-X-Ray Isolated Attosecond Pulses” ,Ultrafast Science 2021: 9828026 (2021).

5. Morimoto, Y., and Baum, P.: “Diffraction andmicroscopy with attosecond electron pulse
trains” , Nat. Phys. 14, 252 (2018).

5. Bing, X., Tamaru, Y., Fu, Y., Yuan, H., Lan, P., Mücke,O.D., Suda, A., Midorikawa, K., and Takahashi, E.J.:“Fully stabilized multi-TW optical waveform
synthesizer: Toward gigawatt isolated attosecond
pulses” , Science Advances 6: eaay2802 (2020).

▲

MemberYuichi Tachibana / Marie Ouille / Yui Yamashita▲

MemberYasuo Nabekawa / Natsuki Kanda /Kotaro Imasaka / Kaito Nishimiya /Dai Ikeda / Rambabu Rajpoot /Ahmed Ramadan Ibrahim / Dianhong Dong /Minshuang Xia

Amplification of single-cycle laser pulses

08

Light-wave modulation of an electron beam09

Extreme Photonics Research Group

Extreme Photonics Research Group

Ultrafast Coherent Soft X-ray Photonics Research Team
Team Leader

Eiji J. Takahashi

Ultrashort Electron Beam Science RIKEN Hakubi Research TeamRIKEN Hakubi Team Leader Yuya Morimoto Ph.D.

D.Eng.

Interdisciplinary Science and Engineering,Engineering, Complex systems

Creating novel ultrafast soft x-ray sources
using the extreme nature of laserSpace-time imaging of the initial steps ofchemical reactions with ultrashort electron beams

Laser is the ultimate light source created by mankind, and it has become an indispensable

Electron beams are used for examples in electron microscopy and electron-beam

tool for our social life. In this laboratory, our main goal is to create an unexplored ultrafast

lithography, where high spatial resolution is required. By using state-of-the-art laser andlaser by using the extreme nature of laser such as ultrashort pulse, super broadband, highelectron-beam technologies, we control the temporal structure of an electron beam withpower, and so on. Specifically, we are developing a high-power a few-cycle laser source,

ultimate attosecond resolution and apply the controlled electron beams for imaging andand using it to develop novel laser source with full coherence in the soft x-ray region and acontrolling ultrafast chemical reactions. We explore the atomic-scale dynamics ofpulse width of attosecond region. We extend the frontier of laser science through theelectrons in a material which is the initial step of most photochemical reactions.

Chemistry, Physics,
Interdisciplinary Science and Engineering,Engineering▲

Keywords▲

Fields▲Fields

▲

1. Lu, X., and Takahashi, E.J.: “Dual-chirped opticalparametric amplification of high-energy single-cycle
laser pulses” , Nature Photonics 18, 99-106 (2024).
2. Bing, X., Tamaru, Y., Fu, Y., Yuan, H., Lan, P., Mücke,O.D., Suda, A., Midorikawa, K., and Takahashi, E.J.:“Gigawatt-class, tabletop, isolated-attosecond-pulse
light source” , Optica 9, 360-363 (2022).

development of novel laser sources.

3. Lu, X., Bing, X., Ishii, N., Itatani, J., Midorikawa, K., andTakahashi, E.J.: “100-mJ class, sub-two-cycle,
carrier-envelope phase-stable dual-chirped opticalparametric amplification” , Opt Lett 47, 3371-3374(2022).

Ultrashort electron beam, Electron beam imaging,
Nonlinear optics, Attosecond science,
Atomic collisions

Publications▲

Publications

Keywords▲

High-power single-cycle laser, Attosecond laser,
MIR laser, Coherent soft x-ray, Strong-field physics

1. Morimoto, Y.: "Attosecond electron-beamtechnology: a review of recent progress” ,Microscopy 72, 2-17 (2023).
2. Morimoto, Y., Shinohara, Y., Tani, M., Chen, B.H.,
Ishikawa, K.L., and Baum, P.: “Asymmetric
single-cycle control of valence electron motion inpolar chemical bonds” , Optica 8, 382 (2021).
3. Morimoto, Y., Hommelhoff, P., and Madsen, L.B.:“Coherent scattering of an optically-modulated
electron beam by atoms” , Phys. Rev. A 103,
043110 (2021).
4. Morimoto, Y., and Baum, P.: “Single-Cycle OpticalControl of Beam Electrons” , Phys. Rev. Lett. 125,
193202 (2020).

4. Bing, X., Tamaru, Y., Fu, Y., Yuan, H., Lan, P., Mücke,O.D., Suda, A., Midorikawa, K., and Takahashi, E.J.: “ACustom-Tailored Multi-TW Optical Electric Field for
Gigawatt Soft-X-Ray Isolated Attosecond Pulses” ,Ultrafast Science 2021: 9828026 (2021).

5. Morimoto, Y., and Baum, P.: “Diffraction andmicroscopy with attosecond electron pulse
trains” , Nat. Phys. 14, 252 (2018).

5. Bing, X., Tamaru, Y., Fu, Y., Yuan, H., Lan, P., Mücke,O.D., Suda, A., Midorikawa, K., and Takahashi, E.J.:“Fully stabilized multi-TW optical waveform
synthesizer: Toward gigawatt isolated attosecond
pulses” , Science Advances 6: eaay2802 (2020).

▲

MemberYuichi Tachibana / Marie Ouille / Yui Yamashita▲

MemberYasuo Nabekawa / Natsuki Kanda /Kotaro Imasaka / Kaito Nishimiya /Dai Ikeda / Rambabu Rajpoot /Ahmed Ramadan Ibrahim / Dianhong Dong /Minshuang Xia

Amplification of single-cycle laser pulses

08

Light-wave modulation of an electron beam09

Subwavelength Photonics Research Group

Subwavelength Photonics Research GroupLive Cell Super-Resolution Imaging Research Team
Deputy Team Leader

Akihiko Nakano

Biotechnological Optics Research Team
Team Leader

D.Sci.

Atsushi Miyawaki

M.D., Ph.D▲

Fields▲FieldsLight is a cutting-edge tool for life science research. Development of useful fluorescent

We label a fluorescent probe on a specific region of a biological molecule and bring itprobes and the advancement of light microscope technologies have brought us a new

back into a cell. We can then visualize how the biological molecule behaves in responseworld of “live” imaging within a cell. We are developing super-resolution confocal live

to external stimulation. Since fluorescence is a physical phenomenon, we can extract▲

imaging microscopy (SCLIM) by the combination of a high-speed confocal scanner and avarious kinds of information by making full use of its characteristics. For example, the

1. Tojima, T., Suda, Y., Jin, N., Kurokawa, K., andNakano，A.: “Spatiotemporal dissection of theGolgi apparatus and the ER-Golgi intermediate
compartment in budding yeast” , eLife 13,
e92900 (2024).

high-sensitivity camera system. With this method we will observe membrane trafficking

excited energy of a fluorescent molecule donor transfers to an acceptor relative to theand organellar dynamics in living cells at high-speed and sub-wavelength space resolution

distance and orientation between the two fluorophores. This phenomenon can be used

(4D) and elucidate underlining molecular mechanisms. We will also try to extend thisto identify interaction between biological molecules or structural change in biological

technology to medical and pharmacological applications.

molecules. Besides, we can apply all other characteristics of fluorescence, such as▲

Keywords

Membrane traffic, Vesicular transport,
Super-resolution live imaging,
Confocal microscopy, Organelles

Publications

2. Obata, Y., Kurokawa, K., Tojima, T., Natsume, M.,
Shiina, I., Takahashi, T., Abe, R., Nakano, A., andNishida, T.: “Golgi retention and oncogenic KIT
signaling via PLCγ2-PKD2-PI4KIIIβ activation in
gastrointestinal stromal tumor cells” , Cell Rep.
42, 113035 (2023).

polarization, quenching, photobleaching, photoconversion, and photochromism, inexperimentation. Cruising inside cells in a super-micro corps, gliding down in a

3. Toshima, J. Y., Tsukahara, A., Nagano, M.,
Tojima, T., Siekhaus, D. E., Nakano, A., andToshima, J.: “The yeast endocytic early/sorting
compartment exists as an independentsub-compartment within the trans-Golgi
network” , eLife 12, e84850 (2023).

microtubule like a roller coaster, pushing our ways through a jungle of chromatin while

4. Shimizu, Y., Takagi, J., Ito, E., Ito, Y., Ebine, K.,
Komatsu, Y., Goto, Y., Sato M., Toyooka, K., Ueda,
T., Kurokawa, K., Uemura, T., and Nakano, A.:“Cargo sorting zones in the trans-Golgi network
visualized by super-resolution confocal live
imaging microscopy in plants” , Nat. Commun.
12:1901 (2021).

science and giving full play to our imagination.

adventurous perspective at all times. What matters is mobilizing all capabilities of

Keywords

Bio-imaging, Fluorescence protein,
Chromophore group

Publications

1. Hirano M., Yonemaru Y., Shimozono S., Sugiyama M,
Ando R, Okada Y, Fujiwara T, and Miyawaki A.
“StayGold photostability under different illumination
modes.” Sci. Rep. 14, 5541 (2024).
2. Ando R, Shimozono S, Ago H, Takagi M, Sugiyama M,
Kurokawa H, Hirano M, Niino Y, Ueno G, Ishidate F,
Fujiwara T, Okada Y, Yamamoto M, and Miyawaki A.
“StayGold variants for molecular fusion andmembrane-targeting applications.” Nat. Methods(2023).
3. Hirano, M., Ando, R., Shimozono, S., Sugiyama, M.,
Takeda, N., Kurokawa, H., Deguchi, R., Endo, K., Haga,
K., Takai-Todaka, R., Inaura, S., Matsumura, Y., Hama,
H., Okada, Y., Fujiwara, T., Morimoto, T., Katayama,K.,
Miyawaki, A.: “A highly photostable and bright green
fluorescent protein” , Nat Biotechnol. 40, 1132–1142(2022).
4. Michikawa, T., Yoshida, T., Kuroki, S., Ishikawa, T.,
Kakei, S., Kimizuka, R., Saito, A., Yokota, H., Shimizu, A.,
Itohara, S., and Miyawaki, A.: “Distributed sensory
coding by cerebellar complex spikes in units ofcortical segments” , Cell Rep.37(6), 109966 (2021).
5. Katayama, H., Hama, H., Nagasawa, K., Kurokawa, H.,
Sugiyama, M., Ando, R., Funata, M., Yoshida, N.,
Homma, M., Nishimura, T., Takahashi, M., Ishida, Y.,
Hioki, H., Tsujihata, Y., and Miyawak,i A.: “Visualizing
and Modulating Mitophagy for Therapeutic Studies of
Neurodegeneration” , Cell 181(5), 1176-1187 (2020).

(Left) SCLIM2 microscope.
(Right) Yeast trans-Golgi network (red) and clathrin-coated vesicles (green) assembling andleaving there. Captured from a high-speed 3D movie taken by SCLIM2.

Member

▲5. Rodriguez-Gallardo, S., Kurokawa, K.,
Sabido-Bozo, S., Cortes-Gomez, A., Ikeda, A.,Zoni, V., Aguilera-Romero, A., Perez-Linero, A.M.,
Lopez, S., Waga, M., Araki, M., Nakano, M.,
Riezman, H., Funato, K., Vanni, S., Nakano, A.,
and Muñiz, M.: “Ceramide chain
length-dependent protein sorting into selective
endoplasmic reticulum exit sites” , Sci. Adv.
6:eaba8237 (2020).

hoisting a flag of nuclear localization signal --- we are reminded to retain a playful andMedicine, dentistry, and pharmacy,
Engineering, Biological Sciences,
Biology / Biochemistry▲

Bioimaging Technologies
by use of glowing proteins▲

Observe nano-scale activities within a living cellby sub-wavelength high-speed imaging

Biological Sciences, Complex systems,
Interdisciplinary science and engineering,
Biology / Biochemistry

Asako Sakaue-Sawano / Masahiko Hirano /Asako Tosaki▲

MemberTakuro Tojima / Kumi Matsuura / Natsuko Jin /Daisuke Miyashiro / Kumiko Ishii / Miho Waga /Hideo Hirukawa

10

Cultured HeLa cells expressing the photoconvertible fluorescent protein, Keade.
Before (left) and after (right) multiple, local irradiation of violet laser light,
green-to-red color conversion occurred in the cytosol or nucleus of targeted cells.

11Subwavelength Photonics Research Group

Subwavelength Photonics Research GroupLive Cell Super-Resolution Imaging Research Team
Deputy Team Leader

Akihiko Nakano

Biotechnological Optics Research Team
Team Leader

D.Sci.

Atsushi Miyawaki

M.D., Ph.D▲

Fields▲FieldsLight is a cutting-edge tool for life science research. Development of useful fluorescent

We label a fluorescent probe on a specific region of a biological molecule and bring itprobes and the advancement of light microscope technologies have brought us a new

back into a cell. We can then visualize how the biological molecule behaves in responseworld of “live” imaging within a cell. We are developing super-resolution confocal live

to external stimulation. Since fluorescence is a physical phenomenon, we can extract▲

imaging microscopy (SCLIM) by the combination of a high-speed confocal scanner and avarious kinds of information by making full use of its characteristics. For example, the

1. Tojima, T., Suda, Y., Jin, N., Kurokawa, K., andNakano，A.: “Spatiotemporal dissection of theGolgi apparatus and the ER-Golgi intermediate
compartment in budding yeast” , eLife 13,
e92900 (2024).

high-sensitivity camera system. With this method we will observe membrane trafficking

excited energy of a fluorescent molecule donor transfers to an acceptor relative to theand organellar dynamics in living cells at high-speed and sub-wavelength space resolution

distance and orientation between the two fluorophores. This phenomenon can be used

(4D) and elucidate underlining molecular mechanisms. We will also try to extend thisto identify interaction between biological molecules or structural change in biological

technology to medical and pharmacological applications.

molecules. Besides, we can apply all other characteristics of fluorescence, such as▲

Keywords

Membrane traffic, Vesicular transport,
Super-resolution live imaging,
Confocal microscopy, Organelles

Publications

2. Obata, Y., Kurokawa, K., Tojima, T., Natsume, M.,
Shiina, I., Takahashi, T., Abe, R., Nakano, A., andNishida, T.: “Golgi retention and oncogenic KIT
signaling via PLCγ2-PKD2-PI4KIIIβ activation in
gastrointestinal stromal tumor cells” , Cell Rep.
42, 113035 (2023).

polarization, quenching, photobleaching, photoconversion, and photochromism, inexperimentation. Cruising inside cells in a super-micro corps, gliding down in a

3. Toshima, J. Y., Tsukahara, A., Nagano, M.,
Tojima, T., Siekhaus, D. E., Nakano, A., andToshima, J.: “The yeast endocytic early/sorting
compartment exists as an independentsub-compartment within the trans-Golgi
network” , eLife 12, e84850 (2023).

microtubule like a roller coaster, pushing our ways through a jungle of chromatin while

4. Shimizu, Y., Takagi, J., Ito, E., Ito, Y., Ebine, K.,
Komatsu, Y., Goto, Y., Sato M., Toyooka, K., Ueda,
T., Kurokawa, K., Uemura, T., and Nakano, A.:“Cargo sorting zones in the trans-Golgi network
visualized by super-resolution confocal live
imaging microscopy in plants” , Nat. Commun.
12:1901 (2021).

science and giving full play to our imagination.

adventurous perspective at all times. What matters is mobilizing all capabilities of

Keywords

Bio-imaging, Fluorescence protein,
Chromophore group

Publications

1. Hirano M., Yonemaru Y., Shimozono S., Sugiyama M,
Ando R, Okada Y, Fujiwara T, and Miyawaki A.
“StayGold photostability under different illumination
modes.” Sci. Rep. 14, 5541 (2024).
2. Ando R, Shimozono S, Ago H, Takagi M, Sugiyama M,
Kurokawa H, Hirano M, Niino Y, Ueno G, Ishidate F,
Fujiwara T, Okada Y, Yamamoto M, and Miyawaki A.
“StayGold variants for molecular fusion andmembrane-targeting applications.” Nat. Methods(2023).
3. Hirano, M., Ando, R., Shimozono, S., Sugiyama, M.,
Takeda, N., Kurokawa, H., Deguchi, R., Endo, K., Haga,
K., Takai-Todaka, R., Inaura, S., Matsumura, Y., Hama,
H., Okada, Y., Fujiwara, T., Morimoto, T., Katayama,K.,
Miyawaki, A.: “A highly photostable and bright green
fluorescent protein” , Nat Biotechnol. 40, 1132–1142(2022).
4. Michikawa, T., Yoshida, T., Kuroki, S., Ishikawa, T.,
Kakei, S., Kimizuka, R., Saito, A., Yokota, H., Shimizu, A.,
Itohara, S., and Miyawaki, A.: “Distributed sensory
coding by cerebellar complex spikes in units ofcortical segments” , Cell Rep.37(6), 109966 (2021).
5. Katayama, H., Hama, H., Nagasawa, K., Kurokawa, H.,
Sugiyama, M., Ando, R., Funata, M., Yoshida, N.,
Homma, M., Nishimura, T., Takahashi, M., Ishida, Y.,
Hioki, H., Tsujihata, Y., and Miyawak,i A.: “Visualizing
and Modulating Mitophagy for Therapeutic Studies of
Neurodegeneration” , Cell 181(5), 1176-1187 (2020).

(Left) SCLIM2 microscope.
(Right) Yeast trans-Golgi network (red) and clathrin-coated vesicles (green) assembling andleaving there. Captured from a high-speed 3D movie taken by SCLIM2.

Member

▲5. Rodriguez-Gallardo, S., Kurokawa, K.,
Sabido-Bozo, S., Cortes-Gomez, A., Ikeda, A.,Zoni, V., Aguilera-Romero, A., Perez-Linero, A.M.,
Lopez, S., Waga, M., Araki, M., Nakano, M.,
Riezman, H., Funato, K., Vanni, S., Nakano, A.,
and Muñiz, M.: “Ceramide chain
length-dependent protein sorting into selective
endoplasmic reticulum exit sites” , Sci. Adv.
6:eaba8237 (2020).

hoisting a flag of nuclear localization signal --- we are reminded to retain a playful andMedicine, dentistry, and pharmacy,
Engineering, Biological Sciences,
Biology / Biochemistry▲

Bioimaging Technologies
by use of glowing proteins▲

Observe nano-scale activities within a living cellby sub-wavelength high-speed imaging

Biological Sciences, Complex systems,
Interdisciplinary science and engineering,
Biology / Biochemistry

Asako Sakaue-Sawano / Masahiko Hirano /Asako Tosaki▲

MemberTakuro Tojima / Kumi Matsuura / Natsuko Jin /Daisuke Miyashiro / Kumiko Ishii / Miho Waga /Hideo Hirukawa

10

Cultured HeLa cells expressing the photoconvertible fluorescent protein, Keade.
Before (left) and after (right) multiple, local irradiation of violet laser light,
green-to-red color conversion occurred in the cytosol or nucleus of targeted cells.

11Subwavelength Photonics Research Group

Subwavelength Photonics Research Group

Image Processing Research Team
Team Leader

Hideo Yokota

Innovative Photon Manipulation Research Team
Team Leader

D.Eng.

Takuo Tanaka

D.Eng.

▲

Keywords▲

Publications

1. Sasaki, S., Mori, T., Enomoto, H., Nakamura, S.,
Yokota, H., Yamashita, H., Goto-Inoue, N.:“Assessing Molecular Localization of Symbiont
Microalgae in Coral Branches Through Mass
Spectrometry Imaging” , Mar Biotechnol (2024).
2. Wang, J., Maeda, E., Tsujimura, Y., Abe, T., Kiyonari,H., Kitaguchi, T., Yokota, H., Matsumoto, T.: “In situ
FRET measurement of cellular tension using
conventional confocal laser microscopy in newly
established reporter mice expressing actinin
tension sensor” , Scientific Reports. 13, Article
number, 22729 (2023).

Lightwave manipulation
by subwavelength structures

Our goal is to develop original RIKEN data processing technology and multidimensional

Our team intensively studies novel photon manipulation technologies using knowledge

measurement technology in order to contribute to understanding biological phenomena.

and experiences obtained from the researches on light wave interaction withWe are especially contributing to the fields of mathematical biology, bio-medical

sub-wavelength fine structures. These photon manipulation technologies will be applied

simulations as well as medical diagnostic and treatment technology by researching andfor three-dimensional nanofabrication systems, ultra-high sensitive molecular sensing

developing new data and image processing technologies and establishing new tools fordevices, and so on. Figure (a) shows a scanning electron microscope image of RIKEN’ squantification of biological phenomena, intended for researchers both inside and outside

logo consists of a sub-wavelength aluminum structure, which absorbs light of certain

1. Chu, C. H., Chia, Y.-H., Hsu, H.-C, Vyas, S., Tsai
C.-M., Yamaguchi, T., Tanaka, T., Chen, H.-W., Luo,
Y. , Yang P.-C., and Tsai, D. P.: "Intelligent Phase
Contrast Meta-Microscope System", Nano Letters23, 24, 11630-11637 (2023).

RIKEN.

wavelength determined by its size and shape. Figure (b) shows an observed image of
the RIKEN’ s logo under white light illumination. Figure (c) shows a demonstrated color
palette covering a broad gamut of colors.

3. Takemoto, S., Hori, K., Yoshimasa, S., Nishimura,M., Nakajo, K., Inaba, A., Sasabe, M., Aoyama, N.,
Watanabe, T., Minakata, T., Ikematsu, H., Yokota, H.,
Yano, T.: “Computer-aided demarcation of earlygastric cancer: a pilot comparative study withendoscopists” , Journal of Gastroenterology(2023).

Keywords

Metamaterials, Plasmonics, Nanophotonics,
Near-ﬁeld Optics, Applied Optics

Publications

2. Chen, M. K., Chu, C. H., Liu, X., Zhang, J., Sun, L.,
Yao, J., Fan, Y., Liang, Y., Yamaguchi, T., Tanaka, T.,
and Tsai, D. P.: "Meta-Lens in the Sky", IEEE Access
10, 46552-46557 (2022).
3. Tanaka, T., Yano T., and Kato, R.:"Nanostructure-enhanced infrared spectroscopy",
Nanophotonics 11, 2541-2561 (2022).
4. Jung, W., Jung, Y., Pikhitsa, P., Feng, J., Yang, Y.,
Kim, M., Tsai, H., Tanaka, T., Shin, J., Kim, K., Choi,
H., Rho, J., and Choi, M.: "Three-dimensional
nanoprinting via charged aerosol jets", nature 592,
54 (2021).
5. Olaya, C. M., Hayazawa, N., Hermosa, N., andTanaka, T.: "Angular Goos-H nchen shift sensor
using gold film enhanced by surface plasmon
resonance", J. Phys. Chem. A 125, 451-458(2021).

4. Umebayashi, M., Takemoto, S., Reymond, L.,
Sundukova, M., Hovius, R., Bucci, A., Heppenstall,P.A., Yokota, H., Johnsson, K., Riezman, H.: “Acovalently-linked probe to monitor local membrane
properties surrounding plasma membraneproteins” , Journal of Cell Biology, 222(3):e202206119 (2023).

Member

▲5. Mitsui, T., Mori, A., Takamatsu, T., Kadota, T., Sato,
K., Fukushima, R, Okubo, K., Umezawa, M.,
Takemura, H., Yokota, H., Kuwata, T., Kinoshita, T.,
Ikematsu, H., Yano, T., Maeda, S., Soga, K.,“Evaluating the identification of the extent ofgastric cancer by over-1000 nm near-infrared
hyperspectral imaging using surgical specimens” ,Journal of Biomedical Optics. Vol. 28. Issue 8,086001 (2023).

Engineering, Complex systems,
Interdisciplinary science and engineering▲

Multi dimensional image processing,Multi dimensional imaging, Bioengineering,
Image analysis, Medical engineering

Image processing researchfor scientific information▲

Engineering, Informatics, Computer Science▲

Fields▲FieldsNorihiko Hayazawa /Maria Vanessa Balois Oguchi /Cherrie May Mogueis Olaya /Takeshi Yamaguchi
Image Processing Cloud▲

MemberShin Yoshizawa / Satoshi Oota / Shigeho Noda /Takashi Michikawa / Satoko Takemoto /Sakiko Nakamura / Yuki Tsujimura /Masaomi Nishimura / Shuning Han /Kotaro Oikawa

12

Colors created by metamaterial absorber that consists of subwavelength aluminum structure.

13

Subwavelength Photonics Research Group

Subwavelength Photonics Research Group

Image Processing Research Team
Team Leader

Hideo Yokota

Innovative Photon Manipulation Research Team
Team Leader

D.Eng.

Takuo Tanaka

D.Eng.

▲

Keywords▲

Publications

1. Sasaki, S., Mori, T., Enomoto, H., Nakamura, S.,
Yokota, H., Yamashita, H., Goto-Inoue, N.:“Assessing Molecular Localization of Symbiont
Microalgae in Coral Branches Through Mass
Spectrometry Imaging” , Mar Biotechnol (2024).
2. Wang, J., Maeda, E., Tsujimura, Y., Abe, T., Kiyonari,H., Kitaguchi, T., Yokota, H., Matsumoto, T.: “In situ
FRET measurement of cellular tension using
conventional confocal laser microscopy in newly
established reporter mice expressing actinin
tension sensor” , Scientific Reports. 13, Article
number, 22729 (2023).

Lightwave manipulation
by subwavelength structures

Our goal is to develop original RIKEN data processing technology and multidimensional

Our team intensively studies novel photon manipulation technologies using knowledge

measurement technology in order to contribute to understanding biological phenomena.

and experiences obtained from the researches on light wave interaction withWe are especially contributing to the fields of mathematical biology, bio-medical

sub-wavelength fine structures. These photon manipulation technologies will be applied

simulations as well as medical diagnostic and treatment technology by researching andfor three-dimensional nanofabrication systems, ultra-high sensitive molecular sensing

developing new data and image processing technologies and establishing new tools fordevices, and so on. Figure (a) shows a scanning electron microscope image of RIKEN’ squantification of biological phenomena, intended for researchers both inside and outside

logo consists of a sub-wavelength aluminum structure, which absorbs light of certain

1. Chu, C. H., Chia, Y.-H., Hsu, H.-C, Vyas, S., Tsai
C.-M., Yamaguchi, T., Tanaka, T., Chen, H.-W., Luo,
Y. , Yang P.-C., and Tsai, D. P.: "Intelligent Phase
Contrast Meta-Microscope System", Nano Letters23, 24, 11630-11637 (2023).

RIKEN.

wavelength determined by its size and shape. Figure (b) shows an observed image of
the RIKEN’ s logo under white light illumination. Figure (c) shows a demonstrated color
palette covering a broad gamut of colors.

3. Takemoto, S., Hori, K., Yoshimasa, S., Nishimura,M., Nakajo, K., Inaba, A., Sasabe, M., Aoyama, N.,
Watanabe, T., Minakata, T., Ikematsu, H., Yokota, H.,
Yano, T.: “Computer-aided demarcation of earlygastric cancer: a pilot comparative study withendoscopists” , Journal of Gastroenterology(2023).

Keywords

Metamaterials, Plasmonics, Nanophotonics,
Near-ﬁeld Optics, Applied Optics

Publications

2. Chen, M. K., Chu, C. H., Liu, X., Zhang, J., Sun, L.,
Yao, J., Fan, Y., Liang, Y., Yamaguchi, T., Tanaka, T.,
and Tsai, D. P.: "Meta-Lens in the Sky", IEEE Access
10, 46552-46557 (2022).
3. Tanaka, T., Yano T., and Kato, R.:"Nanostructure-enhanced infrared spectroscopy",
Nanophotonics 11, 2541-2561 (2022).
4. Jung, W., Jung, Y., Pikhitsa, P., Feng, J., Yang, Y.,
Kim, M., Tsai, H., Tanaka, T., Shin, J., Kim, K., Choi,
H., Rho, J., and Choi, M.: "Three-dimensional
nanoprinting via charged aerosol jets", nature 592,
54 (2021).
5. Olaya, C. M., Hayazawa, N., Hermosa, N., andTanaka, T.: "Angular Goos-H nchen shift sensor
using gold film enhanced by surface plasmon
resonance", J. Phys. Chem. A 125, 451-458(2021).

4. Umebayashi, M., Takemoto, S., Reymond, L.,
Sundukova, M., Hovius, R., Bucci, A., Heppenstall,P.A., Yokota, H., Johnsson, K., Riezman, H.: “Acovalently-linked probe to monitor local membrane
properties surrounding plasma membraneproteins” , Journal of Cell Biology, 222(3):e202206119 (2023).

Member

▲5. Mitsui, T., Mori, A., Takamatsu, T., Kadota, T., Sato,
K., Fukushima, R, Okubo, K., Umezawa, M.,
Takemura, H., Yokota, H., Kuwata, T., Kinoshita, T.,
Ikematsu, H., Yano, T., Maeda, S., Soga, K.,“Evaluating the identification of the extent ofgastric cancer by over-1000 nm near-infrared
hyperspectral imaging using surgical specimens” ,Journal of Biomedical Optics. Vol. 28. Issue 8,086001 (2023).

Engineering, Complex systems,
Interdisciplinary science and engineering▲

Multi dimensional image processing,Multi dimensional imaging, Bioengineering,
Image analysis, Medical engineering

Image processing researchfor scientific information▲

Engineering, Informatics, Computer Science▲

Fields▲FieldsNorihiko Hayazawa /Maria Vanessa Balois Oguchi /Cherrie May Mogueis Olaya /Takeshi Yamaguchi
Image Processing Cloud▲

MemberShin Yoshizawa / Satoshi Oota / Shigeho Noda /Takashi Michikawa / Satoko Takemoto /Sakiko Nakamura / Yuki Tsujimura /Masaomi Nishimura / Shuning Han /Kotaro Oikawa

12

Colors created by metamaterial absorber that consists of subwavelength aluminum structure.

13

Subwavelength Photonics Research Group

Subwavelength Photonics Research Group

Advanced Laser Processing Research Team
Team Leader

Koji Sugioka

Digital Twin for Light-Matter Interaction RIKEN ECL Research TeamRIKEN ECL Team Leader Shuntaro Tani Ph.D

D.Eng.

▲

Fields▲FieldsEngineering, Materials Sciences,
Interdisciplinary science and engineering,Multidisciplinary

Femtosecond laser, Laser processing,Micro/nanofabrication, 3D fabrication, Biochip

1. Zhang, J., Obata, K., Ozasa, K., Uzawa, T., Ito, Y.,
Sugioka, K.: “Rapid manufacturing of glass-based
digital nucleic acid amplification chips by ultrafast
Bessel pulses” , Small Sci. 4, 2300166 (2024).
2. Kawabata, S., Bai, S., Obata, K., Miyaji, G., and
Sugioka, K.: “Two-dimensional laser-induced
periodic surface structures formed on crystalline
silicon by GHz burst mode femtosecond laser
pulses” , Int. J. Extreme Manuf. 5, 015004 (2023).
3. Bai, S., Serien, D., Ma, Y., Obata, K., and Sugioka,
K.: “Attomolar sensing based on liquid-interface
assisted surface enhanced Raman scattering in
microfluidic chip by femtosecond laser
processing” , ACS Appl. Mater. Interfaces 12,42328–4233 (2020).

Our research team is developing advanced laser processing techniques which realize

With the advancement of laser technology, we can now apply laser fields onto materials,

low environmental load, high quality, high efficiency fabrication of materials. In

the strength of which is comparable to the interatomic bonds of the materials

particular, by using femtosecond lasers, novel material processing techniques including

themselves. These strong and controllable light electric fields are expected to be

3D fabrication, surface nanostructuring, novel nanomaterial synthesis, and tailoredutilized in precise laser processing and various forms of material state control.

beam processing are developed, which are applied to fabricate highly functional

However, the physics underlying irreversible processes, such as the fragmentation of a

micro/nanodevices. As one of examples, our team successfully fabricated 3D

continuous solid into discrete atoms, remains not fully understood. At present,

microfluidic surface enhanced Raman spectroscopy (SERS) chips by combining

extensive trial and error is necessary to control these processes. In this researchdifferent types of femtosecond laser processing (hybrid femtosecond laser processing).

project, we aim to develop a method to extract the 'context' of phenomena by

The fabricated SERS chips enabled real-time sensing of trace substances as well as

extensively observing microscopic processes beginning with photoexcitation, throughultrasensitive detection of analytes at attomolar-level concentrations. The developed

the complete automation of experiments. Utilizing this technique, we intend to elucidate

technique will offer high sensitivity diagnosis of diseases such as viral infection andthe governing equations of materials' irreversible transformation and construct a digital

Alzheimer's disease in early stages.

twin for optimizing these processes.

4. Bai, S., Serien, D., Hu, A., and Sugioka, K.:“Three-dimensional microfluidic SERS chips
fabricated by all-femtosecond-laser- processing
for real-time sensing of toxic substances” , Adv.
Funct. Mater. 28, 1706262 (2018).

Interdisciplinary science and engineering,
Physics, Engineering

Keywords

Precision laser processing, Ultrafast spectroscopy,
Deep learning, Digital Twin, Autonomous experiment

Publications▲▲

Publications

Constructing Digital Twinfor Multi-Scale Phenomena Driven by Photo-Excitation▲▲

Keywords

Femtosecond Laser 3D Processing:
Fabrication of Highly Functional Micro/Nanosystems

1. Endo, T., Tani, S., Sakurai, H., and Kobayashi, Y.:“Probing thermal dissipation dimensionality tolaser ablation in the pulse duration range from 300
fs to 1 µs” , Opt. Express 31, 36027 (2023).
2. Tani, S., and Kobayashi, Y.:"Pulse-by-pulse
evolution of surface morphology driven by
femtosecond laser pulses", J. Appl Phys. 133,
143104 (2023).
3. Shimahara, K., Tani, S., Sakurai, H., and Kobayashi,Y.:” A deep learning-based predictive simulator forthe optimization of ultrashort pulse laser drilling",
Commun. Eng. 2, 1 (2023).
4. Tani, S., Sugiyama, K., Sukegawa, T., Sato, T.,
Ishizuka, Y., Taya, S., Feng, F., Komeda, O., Suto, H.,
Saitoh, H., and Kobayashi, Y.:” Real-timehigh-spectral-resolution mid-infrared spectroscopy
with a signal-to-noise ratio of ten thousand” , Opt.
Express 30, 36813 (2022).
5. Tani, S., and Kobayashi, Y.:"Ultrafast laser ablation
simulator using deep neural networks” , Sci. Rep.
12, 5837 (2022).

5. Wu, D., Xu, J., Niu, L., Wu, S., Midorikawa, K., and
Sugioka, K.: “In-channel integration of designablemicrooptical devices using flat
scaffold-supported femtosecond-laser
microfabrication for coupling-free optofluidic cellcounting” , Light Sci. Appl. 4, e228 (2014).

▲

Member▲MemberKotaro Obata / Shi Bai / Jiawei Zhang /Ashkan MomeniBidzard / Kazunari Ozasa /Shota Kawabata(Left) Schematic illustration of a new SERS sensing scheme (Liquid Interface Assisted SERS:
LI-SERS) enabling attomolar sensing.
(Right) Analysis of R6G solution at a concentration of 10-17 M by LI-SERS using a microfluidic SERS chip.

14

Energy diagram of material destruction driven by ultrafast laser pulses

15

Subwavelength Photonics Research Group

Subwavelength Photonics Research Group

Advanced Laser Processing Research Team
Team Leader

Koji Sugioka

Digital Twin for Light-Matter Interaction RIKEN ECL Research TeamRIKEN ECL Team Leader Shuntaro Tani Ph.D

D.Eng.

▲

Fields▲FieldsEngineering, Materials Sciences,
Interdisciplinary science and engineering,Multidisciplinary

Femtosecond laser, Laser processing,Micro/nanofabrication, 3D fabrication, Biochip

1. Zhang, J., Obata, K., Ozasa, K., Uzawa, T., Ito, Y.,
Sugioka, K.: “Rapid manufacturing of glass-based
digital nucleic acid amplification chips by ultrafast
Bessel pulses” , Small Sci. 4, 2300166 (2024).
2. Kawabata, S., Bai, S., Obata, K., Miyaji, G., and
Sugioka, K.: “Two-dimensional laser-induced
periodic surface structures formed on crystalline
silicon by GHz burst mode femtosecond laser
pulses” , Int. J. Extreme Manuf. 5, 015004 (2023).
3. Bai, S., Serien, D., Ma, Y., Obata, K., and Sugioka,
K.: “Attomolar sensing based on liquid-interface
assisted surface enhanced Raman scattering in
microfluidic chip by femtosecond laser
processing” , ACS Appl. Mater. Interfaces 12,42328–4233 (2020).

Our research team is developing advanced laser processing techniques which realize

With the advancement of laser technology, we can now apply laser fields onto materials,

low environmental load, high quality, high efficiency fabrication of materials. In

the strength of which is comparable to the interatomic bonds of the materials

particular, by using femtosecond lasers, novel material processing techniques including

themselves. These strong and controllable light electric fields are expected to be

3D fabrication, surface nanostructuring, novel nanomaterial synthesis, and tailoredutilized in precise laser processing and various forms of material state control.

beam processing are developed, which are applied to fabricate highly functional

However, the physics underlying irreversible processes, such as the fragmentation of a

micro/nanodevices. As one of examples, our team successfully fabricated 3D

continuous solid into discrete atoms, remains not fully understood. At present,

microfluidic surface enhanced Raman spectroscopy (SERS) chips by combining

extensive trial and error is necessary to control these processes. In this researchdifferent types of femtosecond laser processing (hybrid femtosecond laser processing).

project, we aim to develop a method to extract the 'context' of phenomena by

The fabricated SERS chips enabled real-time sensing of trace substances as well as

extensively observing microscopic processes beginning with photoexcitation, throughultrasensitive detection of analytes at attomolar-level concentrations. The developed

the complete automation of experiments. Utilizing this technique, we intend to elucidate

technique will offer high sensitivity diagnosis of diseases such as viral infection andthe governing equations of materials' irreversible transformation and construct a digital

Alzheimer's disease in early stages.

twin for optimizing these processes.

4. Bai, S., Serien, D., Hu, A., and Sugioka, K.:“Three-dimensional microfluidic SERS chips
fabricated by all-femtosecond-laser- processing
for real-time sensing of toxic substances” , Adv.
Funct. Mater. 28, 1706262 (2018).

Interdisciplinary science and engineering,
Physics, Engineering

Keywords

Precision laser processing, Ultrafast spectroscopy,
Deep learning, Digital Twin, Autonomous experiment

Publications▲▲

Publications

Constructing Digital Twinfor Multi-Scale Phenomena Driven by Photo-Excitation▲▲

Keywords

Femtosecond Laser 3D Processing:
Fabrication of Highly Functional Micro/Nanosystems

1. Endo, T., Tani, S., Sakurai, H., and Kobayashi, Y.:“Probing thermal dissipation dimensionality tolaser ablation in the pulse duration range from 300
fs to 1 µs” , Opt. Express 31, 36027 (2023).
2. Tani, S., and Kobayashi, Y.:"Pulse-by-pulse
evolution of surface morphology driven by
femtosecond laser pulses", J. Appl Phys. 133,
143104 (2023).
3. Shimahara, K., Tani, S., Sakurai, H., and Kobayashi,Y.:” A deep learning-based predictive simulator forthe optimization of ultrashort pulse laser drilling",
Commun. Eng. 2, 1 (2023).
4. Tani, S., Sugiyama, K., Sukegawa, T., Sato, T.,
Ishizuka, Y., Taya, S., Feng, F., Komeda, O., Suto, H.,
Saitoh, H., and Kobayashi, Y.:” Real-timehigh-spectral-resolution mid-infrared spectroscopy
with a signal-to-noise ratio of ten thousand” , Opt.
Express 30, 36813 (2022).
5. Tani, S., and Kobayashi, Y.:"Ultrafast laser ablation
simulator using deep neural networks” , Sci. Rep.
12, 5837 (2022).

5. Wu, D., Xu, J., Niu, L., Wu, S., Midorikawa, K., and
Sugioka, K.: “In-channel integration of designablemicrooptical devices using flat
scaffold-supported femtosecond-laser
microfabrication for coupling-free optofluidic cellcounting” , Light Sci. Appl. 4, e228 (2014).

▲

Member▲MemberKotaro Obata / Shi Bai / Jiawei Zhang /Ashkan MomeniBidzard / Kazunari Ozasa /Shota Kawabata(Left) Schematic illustration of a new SERS sensing scheme (Liquid Interface Assisted SERS:
LI-SERS) enabling attomolar sensing.
(Right) Analysis of R6G solution at a concentration of 10-17 M by LI-SERS using a microfluidic SERS chip.

14

Energy diagram of material destruction driven by ultrafast laser pulses

15

Terahertz-wave Research Group

Tera-Photonics Research Team0\
.DJDNXGRTeam Leader

Hiroaki Minamide

D.Eng.

$WWUDFWHGE\WKHLQILQLWHSRVVLELOLWLHVRIODVHUV'LUHFWRU
5,.(1&HQWHUIRU$GYDQFHG3KRWLQLFV'U.DWVXPL0LGRULNDZD▲

Fields.ZFODPVOUFSXJUIMBTFST     "CPVU  ZFBST BHP  XIFO * XBT B HSBEVBUF TUVEFOU  * CFHBO SFTFBSDIJOH MBTFST BT B NFBOT PG HFOFSBUJOH
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Our team develops state-of-the-art frequency-tunable THz-wave sources which exploit
new THz-wave application fields. A nonlinear optical process is utilized for realizing theTHz-wave source which lights up the THz-wave gray zone, and our original design andmethod will be demonstrated. We develop THz sources with high output, wide tunability,
high stability and narrow linewidth.
Active collaboration with both internal and external research groups is carried out for
exploring new applications by development of instrument combined with new THz-wave
sources. Advanced THz-wave technologies are also being developed in cooperation

0OFEJTDPWFSZBGUFSBOPUIFSNBEFUIFJNQPTTJCMFQPTTJCMF     *O UIF FBSMZ T  UIF MBTFS DPNNVOJUZ XBT FYDJUFE CZ UIF JEFB UIBU 9SBZT XPVME CF UIF OFYU CJH UIJOH)PXFWFS  BU 3*,&/ XF DPVME OPU QSPEVDF 9SBZ MBTFST BU UIBU UJNF  BT JU SFRVJSFE B IVHF FYDJUBUJPO MBTFS 8IJMF
XF XFSF UIJOLJOH BCPVU XIBU UP EP  B SFWPMVUJPOBSZ NFUIPE DBMMFE iDIJSQFEQVMTF BNQMJGJDBUJPOw GPS XIJDI UIF/PCFM1SJ[FJO1IZTJDTXBTBXBSEFE XBTEFWFMPQFE BMMPXJOHBESBNBUJDJODSFBTFJOMBTFSJOUFOTJUZ BOEXF
SFBMJ[FEUIBUJUNJHIUCFQPTTJCMFUPVTFUIJTNFUIPEUPEFWFMPQBEFTLUPQTJ[FEMBTFSEFWJDF     )PXFWFS  BT XF TUBSUFE EFWFMPQJOH UIF EFWJDF  XF GPVOE UIBU UIF MBDL PG BO 9SBZ NJSSPS NBEF JU JNQPTTJCMF
UP BNQMJGZ UIF 9SBZT XJUI UIF QIBTF QPTJUJPO PG UIF XBWFhT QFBLT BOE WBMMFZT  BMJHOFE "SPVOE UIBU UJNF UIFQIFOPNFOPOPGiIJHIPSEFSIBSNPOJDT wGPSXIJDIUIF/PCFM1SJ[FJO1IZTJDTXBTBXBSEFE XBTEJTDPWFSFE 
BOEJUXBTGPVOEUIBUBMUIPVHIUIFPVUQVUXPVMECFXFBL JUXBTQPTTJCMFUPTIPSUFOUIFXBWFMFOHUIJOBQIBTFBMJHOFE NBOOFS 6TJOH UIJT QIFOPNFOPO  JO  XF TVDDFFEFE JO EFWFMPQJOH BO BUUPTFDPOE QVMTF MBTFS XJUIIJHI PVUQVU QPXFS JO UIF 9SBZ XBWFMFOHUI SBOHF 5IF NFUIPE XF VTFE JT OPX UIF JOUFSOBUJPOBM TUBOEBSE GPSIJHIPSEFSIBSNPOJDT"MUIPVHIUIFEFWFMPQNFOUPGUIJTEFWJDFXBTNBEFQPTTJCMFCZEJTDPWFSJFTXIJDIDPVMECFOPNJOBUFEGPSUIF/PCFM 1SJ[F  UIF BDUVBM EFWFMPQNFOU PG UIF EFWJDF XBT WFSZ EJGGJDVMU 8F TUSVHHMFE XJUI UIF MBDL PG MBTFSJOUFOTJUZ EVSJOH UIF EFWFMPQNFOU CVU XFSF MVDLZ  CFDBVTF XF VOJOUFOUJPOBMMZ SFNPWFE UIF IPMMPX GJCFS VTFE UP
DPOGJOFUIFMBTFSCFBN BOEGPVOEUIBUEPJOHUIJTJNQSPWFEUIFJOUFOTJUZBOETPMWFEUIFQSPCMFN

with industry to establish practical THz-wave sources and technologies in the world.

Development of kilo-watt-power Terahertz-wave
source, Sensitive Terahertz-wave detection,
Terahertz-wave applications,Nondestructive measurements, Nonlinear optics

Publications

1. Nishida, M., Notake, T., Takida, Y., Hirosawa, K.,
Ohata, N., and Minamide, H.: “High-repetition-rate
injection-seeded terahertz-wave parametric
generation pumped by a 1.5 μm sub-nanosecond
laser” , Appl. Phys. Lett. 124, 12 121105 (2024).
2. Satou, A., Negoro, T., Narita, K., Hosotani, T.,
Tamura, K., Tang, C., Lin, T.-T., Retaux, P.-E., Takida,Y., Minamide, H., Suemitsu, T., and Otsuji, T.:“Gate-readout and a 3D rectification effect for
giant responsivity enhancement of asymmetricdual-grating-gate plasmonic terahertz detectors” ,Nanophotonics 12, 23 4283–4295 (2023).
3. Shirato, M., Takida, Y., Kanno, T., Matsuura, H.,
Niwano, Y., Minamide, H., Nakamura, K.:“Mutagenicity assessment of high-power 1.6-THz
pulse laser radiation” , Photochem. Photobiol. 100,
146-158 (2023).
4. Muldera, J.E., Nawata, K., Takida, Y., Yadav, D., andMinamide, H.: “Tunable backward terahertz-wave
parametric oscillator centered at a high frequencyof 0.87 THz with injection seeding” , Opt. Express
31, 15 23966-23973 (2023).
5. Tamura, K., Tang, C., Ogiura, D., Suwa, K.,
Fukidome, H., Takida, Y., Minamide, H., Suemitsu,
T., Otsuji, T., and Satou, A.: “Fast and sensitive
terahertz detection with a current-driven
epitaxial-graphene asymmetric dual-grating-gate
field-effect transistor structure” , APL Photonics 7,
12 126101 (2022).

"UUPTFDPOEQVMTFMBTFSTIBWFDIBOHFEUIFXPSME

0OFPGUIFUIJOHTXFXBOUFEUPEPXBTUPCFBCMFNFBTVSFUIFMFOHUIPGBUUPTFDPOEQVMTFT8IFOZPVMPPL

Member▲

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Engineering,Interdisciplinary science and engineering▲

Leading Terahertz science & applications
with innovative Tera-photonics technology

Yuma Takida / Joselito Muldera /Deepika Yadav / Alexander De Los Reyes /Backward terahertz parametric oscillator（left）, PPLN crystals（top right）,
and THz-wave imaging (bottom right)

Yuehong Xu*OUFSWJFXTBOEDPNQPTJUJPO"LJLP*LFEB 1IPUPHSBQIZ5BEBTIJ"J[BXB

Reprinted from RIKEN NEWS 2024 Summer
16

17

Terahertz-wave Research Group

Tera-Photonics Research Team0\
.DJDNXGRTeam Leader

Hiroaki Minamide

D.Eng.

$WWUDFWHGE\WKHLQILQLWHSRVVLELOLWLHVRIODVHUV'LUHFWRU
5,.(1&HQWHUIRU$GYDQFHG3KRWLQLFV'U.DWVXPL0LGRULNDZD▲

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Our team develops state-of-the-art frequency-tunable THz-wave sources which exploit
new THz-wave application fields. A nonlinear optical process is utilized for realizing theTHz-wave source which lights up the THz-wave gray zone, and our original design andmethod will be demonstrated. We develop THz sources with high output, wide tunability,
high stability and narrow linewidth.
Active collaboration with both internal and external research groups is carried out for
exploring new applications by development of instrument combined with new THz-wave
sources. Advanced THz-wave technologies are also being developed in cooperation

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DPOGJOFUIFMBTFSCFBN BOEGPVOEUIBUEPJOHUIJTJNQSPWFEUIFJOUFOTJUZBOETPMWFEUIFQSPCMFN

with industry to establish practical THz-wave sources and technologies in the world.

Development of kilo-watt-power Terahertz-wave
source, Sensitive Terahertz-wave detection,
Terahertz-wave applications,Nondestructive measurements, Nonlinear optics

Publications

1. Nishida, M., Notake, T., Takida, Y., Hirosawa, K.,
Ohata, N., and Minamide, H.: “High-repetition-rate
injection-seeded terahertz-wave parametric
generation pumped by a 1.5 μm sub-nanosecond
laser” , Appl. Phys. Lett. 124, 12 121105 (2024).
2. Satou, A., Negoro, T., Narita, K., Hosotani, T.,
Tamura, K., Tang, C., Lin, T.-T., Retaux, P.-E., Takida,Y., Minamide, H., Suemitsu, T., and Otsuji, T.:“Gate-readout and a 3D rectification effect for
giant responsivity enhancement of asymmetricdual-grating-gate plasmonic terahertz detectors” ,Nanophotonics 12, 23 4283–4295 (2023).
3. Shirato, M., Takida, Y., Kanno, T., Matsuura, H.,
Niwano, Y., Minamide, H., Nakamura, K.:“Mutagenicity assessment of high-power 1.6-THz
pulse laser radiation” , Photochem. Photobiol. 100,
146-158 (2023).
4. Muldera, J.E., Nawata, K., Takida, Y., Yadav, D., andMinamide, H.: “Tunable backward terahertz-wave
parametric oscillator centered at a high frequencyof 0.87 THz with injection seeding” , Opt. Express
31, 15 23966-23973 (2023).
5. Tamura, K., Tang, C., Ogiura, D., Suwa, K.,
Fukidome, H., Takida, Y., Minamide, H., Suemitsu,
T., Otsuji, T., and Satou, A.: “Fast and sensitive
terahertz detection with a current-driven
epitaxial-graphene asymmetric dual-grating-gate
field-effect transistor structure” , APL Photonics 7,
12 126101 (2022).

"UUPTFDPOEQVMTFMBTFSTIBWFDIBOHFEUIFXPSME

0OFPGUIFUIJOHTXFXBOUFEUPEPXBTUPCFBCMFNFBTVSFUIFMFOHUIPGBUUPTFDPOEQVMTFT8IFOZPVMPPL

Member▲

BU UIF DPNCMJLF TQFDUSB PG IJHI PSEFS IBSNPOJDT  JU JT FBTZ UP JNBHJOF B TFSJFT PG BUUPTFDPOE QVMTFT XJUI UJNFXJEUIT CFJOH BMJHOFE )PXFWFS  NFBTVSJOH QVMTF XJEUIT JO UIF 9SBZ SFHJPO  XIFSF  VOMJLF JO UIF WJTJCMF
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Keywords▲     " iMBTFSw JT BO BSUJGJDJBMMZ DSFBUFE CFBN PG MJHIU UIBU USBWFMT JO B TUSBJHIU MJOF BU B TJOHMF XBWFMFOHUI -BTFSTIBWF B XJEF SBOHF PG BQQMJDBUJPOT JODMVEJOH NJDSP QSPDFTTJOH  DPNNVOJDBUJPOT  BOE NJDSPTDPQJD PCTFSWBUJPO 
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Engineering,Interdisciplinary science and engineering▲

Leading Terahertz science & applications
with innovative Tera-photonics technology

Yuma Takida / Joselito Muldera /Deepika Yadav / Alexander De Los Reyes /Backward terahertz parametric oscillator（left）, PPLN crystals（top right）,
and THz-wave imaging (bottom right)

Yuehong Xu*OUFSWJFXTBOEDPNQPTJUJPO"LJLP*LFEB 1IPUPHSBQIZ5BEBTIJ"J[BXB

Reprinted from RIKEN NEWS 2024 Summer
16

17

Terahertz-wave Research GroupTerahertz-wave Research GroupTerahertz Sensing and Imaging Research Team
Team Leader

Chiko Otani

D.Sci

Terahertz Quantum Device Research Team
Team Leader

Hideki Hirayama

D.Eng.

▲

Fields

1. De Miguel, J., Hernández-Cabrera, J. F.,
Hernández-Suárez, E., Joven-Álvarez, E. Otani, C.,
and Rubiño-Martín, J. A.: “Discovery prospects
with the Dark-photons & Axion-Like particles
Interferometer” , Physical Review. D 19, 6, 062002(2024).
2. Feng, C. H., Otani, C., and Hoshina, H.:“Characterization of Different Types of Crystallizationfrom Cocoa Butter by Using Terahertz Spectroscopy,”
Appl. Sci. 14, 35 (2024).

soft materials and their spectral absorption features. These characteristics can be utilized
for many applications in various scientific and industrial fields. In this team, we aredeveloping novel technologies, science and applications in THz sensing, imaging, anddetection. In particular, we are conducting research and development on the control ofmolecular structure and function by THz-wave irradiation, high-sensitivity imaging andobservations using superconducting detectors as well as the collaborative research anddevelopment with companies.

Development ofcompact and potable terahertz laser source
Terahertz light having both the transparency of radio wave and the high resolution of lightis expected to be used in a wide range of application fields as a light source for various
perspective and nondestructive inspections. We are developing THz-QCL (terahertz
quantum-cascade laser), which is expected to be a very compact, portable, high power
terahertz light source. Through the introduction of a new quantum subband structure
and/or nitride semiconductors, THz-QCL aiming for implementation in society is being
developed by performing room temperature oscillation and enlarging the operating
frequency region which have been impossible so far. By developing the next generationcompact terahertz imaging devices, we would like to contribute to the realization of aprosperous society in the near future.

3. Ikari, T., Sasaki, Y., and Otani, C.: “275-305 GHz
FM-CW radar 3D imaging for walk-throughsecurity body scanner” , Photonics. 10, 3, 343(2023).

5. Lee, K., Génova-Santos, R. T., Hazumi, M., Honda, S.,
Kutsuma, H., Oguri, S., Otani, C., Peel, M. W., Suzuki, J.,
Tajima, O., Won, E.: “A forecast of the sensitivity on themeasurement of the optical depth to reionization with
the GroundBIRD experiment” , Astrophys. J., 915, 88(2021).

1. Wang, L., Lin, T. T., Wang, K., and Hirayama, H.:“Clean three-level direct-phonon injection terahertz
quantum cascade laser” , Applied Physics Letters,Vol. 122, pp. 221103 (2023).
2. Wang, L., Chen, M., Lin, T. T., Wang, K., andHirayama, H.: “Interdiffusion limiting on
self-consistent optical gain in terahertz quantum
cascade lasers” , Applied Physics Express Vol. 16,072004 (2023).
3. Wang, L., Lin, T. T., Chen, M., Wang, K., andHirayama, H.: “Terahertz quantum cascade laser
considering compositional interdiffusion effect” ,Applied Physics Express Vol. 16, pp. 032007(2023).

Member▲▲Javier De Miguel Hernandez / Shinsuke Uno /Publications

5. Lin, T. T., Wang, L., Wang, K., Grange, T., Birner, S.,
and Hirayama, H.:” Over one watt output power
terahertz quantum cascade lasers by using highdoping concentration and variable barrier-wellheight” , physica status solidi RRL, Vol. 16, pp.
2200033 (2022).

Member

Shusaku Nakajima / Yuto Kamei /Terahertz, Quantum cascade lasers,
Inter-subband transition,
Nitride semiconductors lasers,
Molecular-beam epitaxy

4. Lin, T. T., Wang, L., Wang, K., Grange, T., Birner, S.,
Miyoshi, T., and Hirayama, H.:” Increasing theoutput power of a heavily doped terahertz
quantum cascade laser by avoiding the subband
misalignment” , Journal of Applied Physics, Vol.
132, pp. 173101-1-10 (2022).

4. Yamazaki, S., Ueno, Y., Hosoki, R., Saito, T., Idehara, T.,
Yamaguchi, Y., Otani, C., Ogawa, Y., Harata, M., andHoshina, H.: “THz irradiation inhibits cell division byaffecting actin dynamics” , PloS One 16, e0248381(2021).

Hiromichi Hoshina / Yoshiaki Sasaki /Keywords▲▲

Publications

Terahertz (THz) wave has the unique characteristics such as the transparency to many

Fields

Optical Devise Engineering, Quantum Electronics,
Semiconductor Physics▲▲

Keywords

Terahertz wave, Spectroscopy and Imaging, Sensing,
Structural and Functional control of biological tissues,
Superconducting detector

Terahertz Sensing,
Imaging and Applications▲

Engineering, Space Science,
Molecular Biology / Genetics, Physics,
Agricultural Sciences, Chemistry,
Interdisciplinary science and engineering

Li Wang / Krishan Kumar /(Left) Inhibition of cell division by actin protein fibrillation in cells by terahertz-wave irradiation (microscopic image).

Shashank Shekhar Mishra / Takayuki Ishida /(Right) VNA spectrum of a thin-film superconducting microwave resonator with a high quality factor (Qi~108).

Kenji Yamazawa / Manabu Kadowaki

Yuya Ueno / Ryota Ito
Photograph and operating properties of terahertz quantum-cascade laser (THz-QCL)

18

19

Terahertz-wave Research GroupTerahertz-wave Research GroupTerahertz Sensing and Imaging Research Team
Team Leader

Chiko Otani

D.Sci

Terahertz Quantum Device Research Team
Team Leader

Hideki Hirayama

D.Eng.

▲

Fields

1. De Miguel, J., Hernández-Cabrera, J. F.,
Hernández-Suárez, E., Joven-Álvarez, E. Otani, C.,
and Rubiño-Martín, J. A.: “Discovery prospects
with the Dark-photons & Axion-Like particles
Interferometer” , Physical Review. D 19, 6, 062002(2024).
2. Feng, C. H., Otani, C., and Hoshina, H.:“Characterization of Different Types of Crystallizationfrom Cocoa Butter by Using Terahertz Spectroscopy,”
Appl. Sci. 14, 35 (2024).

soft materials and their spectral absorption features. These characteristics can be utilized
for many applications in various scientific and industrial fields. In this team, we aredeveloping novel technologies, science and applications in THz sensing, imaging, anddetection. In particular, we are conducting research and development on the control ofmolecular structure and function by THz-wave irradiation, high-sensitivity imaging andobservations using superconducting detectors as well as the collaborative research anddevelopment with companies.

Development ofcompact and potable terahertz laser source
Terahertz light having both the transparency of radio wave and the high resolution of lightis expected to be used in a wide range of application fields as a light source for various
perspective and nondestructive inspections. We are developing THz-QCL (terahertz
quantum-cascade laser), which is expected to be a very compact, portable, high power
terahertz light source. Through the introduction of a new quantum subband structure
and/or nitride semiconductors, THz-QCL aiming for implementation in society is being
developed by performing room temperature oscillation and enlarging the operating
frequency region which have been impossible so far. By developing the next generationcompact terahertz imaging devices, we would like to contribute to the realization of aprosperous society in the near future.

3. Ikari, T., Sasaki, Y., and Otani, C.: “275-305 GHz
FM-CW radar 3D imaging for walk-throughsecurity body scanner” , Photonics. 10, 3, 343(2023).

5. Lee, K., Génova-Santos, R. T., Hazumi, M., Honda, S.,
Kutsuma, H., Oguri, S., Otani, C., Peel, M. W., Suzuki, J.,
Tajima, O., Won, E.: “A forecast of the sensitivity on themeasurement of the optical depth to reionization with
the GroundBIRD experiment” , Astrophys. J., 915, 88(2021).

1. Wang, L., Lin, T. T., Wang, K., and Hirayama, H.:“Clean three-level direct-phonon injection terahertz
quantum cascade laser” , Applied Physics Letters,Vol. 122, pp. 221103 (2023).
2. Wang, L., Chen, M., Lin, T. T., Wang, K., andHirayama, H.: “Interdiffusion limiting on
self-consistent optical gain in terahertz quantum
cascade lasers” , Applied Physics Express Vol. 16,072004 (2023).
3. Wang, L., Lin, T. T., Chen, M., Wang, K., andHirayama, H.: “Terahertz quantum cascade laser
considering compositional interdiffusion effect” ,Applied Physics Express Vol. 16, pp. 032007(2023).

Member▲▲Javier De Miguel Hernandez / Shinsuke Uno /Publications

5. Lin, T. T., Wang, L., Wang, K., Grange, T., Birner, S.,
and Hirayama, H.:” Over one watt output power
terahertz quantum cascade lasers by using highdoping concentration and variable barrier-wellheight” , physica status solidi RRL, Vol. 16, pp.
2200033 (2022).

Member

Shusaku Nakajima / Yuto Kamei /Terahertz, Quantum cascade lasers,
Inter-subband transition,
Nitride semiconductors lasers,
Molecular-beam epitaxy

4. Lin, T. T., Wang, L., Wang, K., Grange, T., Birner, S.,
Miyoshi, T., and Hirayama, H.:” Increasing theoutput power of a heavily doped terahertz
quantum cascade laser by avoiding the subband
misalignment” , Journal of Applied Physics, Vol.
132, pp. 173101-1-10 (2022).

4. Yamazaki, S., Ueno, Y., Hosoki, R., Saito, T., Idehara, T.,
Yamaguchi, Y., Otani, C., Ogawa, Y., Harata, M., andHoshina, H.: “THz irradiation inhibits cell division byaffecting actin dynamics” , PloS One 16, e0248381(2021).

Hiromichi Hoshina / Yoshiaki Sasaki /Keywords▲▲

Publications

Terahertz (THz) wave has the unique characteristics such as the transparency to many

Fields

Optical Devise Engineering, Quantum Electronics,
Semiconductor Physics▲▲

Keywords

Terahertz wave, Spectroscopy and Imaging, Sensing,
Structural and Functional control of biological tissues,
Superconducting detector

Terahertz Sensing,
Imaging and Applications▲

Engineering, Space Science,
Molecular Biology / Genetics, Physics,
Agricultural Sciences, Chemistry,
Interdisciplinary science and engineering

Li Wang / Krishan Kumar /(Left) Inhibition of cell division by actin protein fibrillation in cells by terahertz-wave irradiation (microscopic image).

Shashank Shekhar Mishra / Takayuki Ishida /(Right) VNA spectrum of a thin-film superconducting microwave resonator with a high quality factor (Qi~108).

Kenji Yamazawa / Manabu Kadowaki

Yuya Ueno / Ryota Ito
Photograph and operating properties of terahertz quantum-cascade laser (THz-QCL)

18

19

Advanced Photonics Technology Development Group

Advanced Photonics Technology Development Group

Ultrahigh Precision Optics Technology Team

Photonics Control Technology Team
Team Leader

Satoshi Wada

Team Leader

Ph.D.

Yutaka Yamagata

D.Eng.

FieldsEngineering, Physics, Biology / Biochemistry,
Agricultural Sciences,
Medicine, dentistry, and pharmacy

Particle control and measurement, Medical andagricultural measurement, Trace gas measurement,
Natural energy, Space applications

Our team investigates new optical technologies for solving world-wide environmental

Our team develops advanced ultrahigh-precision/micro fabrication technologies and theirand energy problems. We are mainly developing remote-sensing system of poisonous

application to scientific apparatuses and devices to support advanced scientific research▲

Publications

gas, lidar as an atmospheric monitor for high energy cosmic ray observation, andat RIKEN. Research and development plans of our team include the following four topics:

1. Nakamura, Y., Moriyama, D., Isomura A., Sasoh, A.,
Tsuno, K., Ogawa, T., Wada, S., and Fukushima, T.:“Laser ablation impulse dependence on beam
Spatial-Profile” Optics & Laser Technology,
Volume 169, 110160 (2024).

solar-pumped laser for advanced energy source. We are also developing tunable(1) Development of ultrahigh-precision optics including design, fabrication, metrology andlaser-based biosensors for biomedical and agricultural applications. These researches

computational simulation; (2) Development of ultrahigh-precision/micro fabrication

2. Yumoto, M., Miyata, K., Kawata, Y., and Wada, S.:“Mid-infrared self-difference frequency generation
via random quasi-phase-matching in Cr:ZnSelaser” , Optics & Laser Technology, Volume 169,
110161 (2024).

will contribute to build and to maintain social environment that humans can live safely.

technologies; (3) Development of materials and devices for biology or biochemistry such

Moreover, we are investigating fundamental research topics including particle control

as microfluidic immunoassay devices.

3. Murakami, T., Morishita, K., Koike, K., Fujii, K., andWada, S.: ” Electrolyte potentials and impedance
measurement of polymer electrolyte membrane
CO2 reduction electrolyzer” , Japanese Journal ofApplied Physics, Volume 62, Number SK (2023).

with high power Lyman α coherent source, and development of laser pumped neutron

In all R&D topics, our team collaborates with laboratories inside and outside of RIKEN andsource. New applied researches were performed on the basis of basic research of laser

helps them to construct the most advanced experimental apparatuses, which will lead tomaterials, and nonlinear optics. We are also interested in space debris removable with

innovative scientific research results.

4. Tsuno, K., Koike, K., Fujii, K., Ogawa, T., and Wada,
S.: “User-on-demand Renewable Energy Supply
System Using Modified DC-bus Signaling” ,IFAC-PapersOnLine, Volume 56, Issue 2, Pages
9098-9103 (2023).
5. Nozawa, S., Saito, N., Kawahara, T., Wada, S.,
Tsuda, T. T., Maeda, S., Takahashi, T., Fujiwara, H.,
Narayanan, V. L., Kawabata, T., and Johnsen, M.
G.: “A statistical study of convective and dynamic
instabilities in the polar upper mesosphere above
Tromsø” , Earth, Planets and Space volume 75,
Article number: 22 (2023).

space laser technology.

(a)

(b)

(c)

(d)

Publications

1. Fujiie T., Hino M., Hosobata T., Ichikawa G.,
Kitaguchi M., Mishima K., Seki Y, Shimizu M. H.,
and Yamagata Y.: “Development of NeutronInterferometer Using Multilayer Mirrors andMeasurements of Neutron-Nuclear Scattering
Length with Pulsed Neutron Source” , Phys. Rev.
Lett. 132, 023402 (2024).
2. Iwaguchi, S., Nishizawa, A., Chen, Y., Kawasaki,Y., Ishikawa, T., Kitaguchi, M., Yamagata, Y., Wu,
B., Shimizu, R., Umemura, K., Tsuji, K., Shimizu,
H., Michimura, Y., and Kawamura, S.:"Displacement-noise-free interferometericgravitational-wave detector using unidirectional
neutrons with four speeds", Phys. Lett. A 458,
128581 (2023).

4. Heacock, B., Fujiie, T., Haun, W.R.,.Henins, A.,
Hirota, K., Hosobata, T., Huber, M.G., Kitaguchi,
M., Pushin, D.A., Shimizu, H., Takeda, M.,
Valdillez, R., Yamagata, Y., and Young, A.R.:“Pendellosung interferometry probes theneutron charge radius, lattice dynamics, andfifth forces", Science 373, 1239-1243 (2021).

▲(a) Sodium LIDAR(b) Coherent Lyman-α resonance radiation source for ultra-slow muon generation(c) Laser inspection of infrastructure by courtesy of Shizuoka Pref. and Topcon Corp.
(d) Application of photonics control technology to plant cultivation

Newly Developed Supermirror Neutron Interferometer

5. Yamada, N., L., Hosobata, T., Nemoto, F., Hori, K.,
Hino, M., Izumi, J., Suzuki, K., Hirayama, M.,
Kanno, R., and Yamagata, Y.: “Application of
precise neutron focusing mirrors for neutronreflectometry: latest results and future
prospects” , J. Appl. Cryst. 53 (2020).

Member▲20

Ultrahigh Precision Machining,
Ultrahigh Precision Metrology, Aspherical Optics,
Production Technology, Neutron Optics

3. Aoki, H., Yuki, M., Shimizu, M., Hongoh, Y.,
Ohkuma, M., and Yamagata, Y.: "Agarose gel
microcapsules enable easy-to-prepare,picolitre-scale, single-cell genomics, yielding
high-coverage genome sequences", Sci. Rep. 12,17014–17026 (2022).

MemberNorihito Saito / Kiwamu Kase /Tomoki Matsuyama / Takafumi Sassa /Shigeharu Moriya / Takayo Ogawa /Katsushi Fujii / Kentaro Miyata / Masato Otagiri /Takeharu Murakami / Manabu Inukai /Tatsuya Shinozaki / Hiroshi Kasuga /Michio Sakashita / Katsuhiko Tsuno /Kei Morishita / Yasushi Kawata /Akihiro Tanabashi / Saki Miyajima /Hiroshi Matsutaka /Aya Kashifuku /Tomohiro Tsukihana / Norihiro Matsuyama /Noriko Kurose / Yoko Ono / Takeshi Matsumoto /Miyuki Nara

Keywords▲

Developing advanced optical components
by ultrahigh precision technology▲

Development of photonics control technology
for science and social issues▲

Keywords▲▲

FieldsEngineering,Interdisciplinary science and engineering

Koichiro Shirota / Yusuke Tajima /Yoshiyuki Takizawa / Tetsuya Aoyama /Noboru Ebizuka / Hiroyoshi Aoki /Takuya Hosobata / Masahiro Takeda

21

Advanced Photonics Technology Development Group

Advanced Photonics Technology Development Group

Ultrahigh Precision Optics Technology Team

Photonics Control Technology Team
Team Leader

Satoshi Wada

Team Leader

Ph.D.

Yutaka Yamagata

D.Eng.

FieldsEngineering, Physics, Biology / Biochemistry,
Agricultural Sciences,
Medicine, dentistry, and pharmacy

Particle control and measurement, Medical andagricultural measurement, Trace gas measurement,
Natural energy, Space applications

Our team investigates new optical technologies for solving world-wide environmental

Our team develops advanced ultrahigh-precision/micro fabrication technologies and theirand energy problems. We are mainly developing remote-sensing system of poisonous

application to scientific apparatuses and devices to support advanced scientific research▲

Publications

gas, lidar as an atmospheric monitor for high energy cosmic ray observation, andat RIKEN. Research and development plans of our team include the following four topics:

1. Nakamura, Y., Moriyama, D., Isomura A., Sasoh, A.,
Tsuno, K., Ogawa, T., Wada, S., and Fukushima, T.:“Laser ablation impulse dependence on beam
Spatial-Profile” Optics & Laser Technology,
Volume 169, 110160 (2024).

solar-pumped laser for advanced energy source. We are also developing tunable(1) Development of ultrahigh-precision optics including design, fabrication, metrology andlaser-based biosensors for biomedical and agricultural applications. These researches

computational simulation; (2) Development of ultrahigh-precision/micro fabrication

2. Yumoto, M., Miyata, K., Kawata, Y., and Wada, S.:“Mid-infrared self-difference frequency generation
via random quasi-phase-matching in Cr:ZnSelaser” , Optics & Laser Technology, Volume 169,
110161 (2024).

will contribute to build and to maintain social environment that humans can live safely.

technologies; (3) Development of materials and devices for biology or biochemistry such

Moreover, we are investigating fundamental research topics including particle control

as microfluidic immunoassay devices.

3. Murakami, T., Morishita, K., Koike, K., Fujii, K., andWada, S.: ” Electrolyte potentials and impedance
measurement of polymer electrolyte membrane
CO2 reduction electrolyzer” , Japanese Journal ofApplied Physics, Volume 62, Number SK (2023).

with high power Lyman α coherent source, and development of laser pumped neutron

In all R&D topics, our team collaborates with laboratories inside and outside of RIKEN andsource. New applied researches were performed on the basis of basic research of laser

helps them to construct the most advanced experimental apparatuses, which will lead tomaterials, and nonlinear optics. We are also interested in space debris removable with

innovative scientific research results.

4. Tsuno, K., Koike, K., Fujii, K., Ogawa, T., and Wada,
S.: “User-on-demand Renewable Energy Supply
System Using Modified DC-bus Signaling” ,IFAC-PapersOnLine, Volume 56, Issue 2, Pages
9098-9103 (2023).
5. Nozawa, S., Saito, N., Kawahara, T., Wada, S.,
Tsuda, T. T., Maeda, S., Takahashi, T., Fujiwara, H.,
Narayanan, V. L., Kawabata, T., and Johnsen, M.
G.: “A statistical study of convective and dynamic
instabilities in the polar upper mesosphere above
Tromsø” , Earth, Planets and Space volume 75,
Article number: 22 (2023).

space laser technology.

(a)

(b)

(c)

(d)

Publications

1. Fujiie T., Hino M., Hosobata T., Ichikawa G.,
Kitaguchi M., Mishima K., Seki Y, Shimizu M. H.,
and Yamagata Y.: “Development of NeutronInterferometer Using Multilayer Mirrors andMeasurements of Neutron-Nuclear Scattering
Length with Pulsed Neutron Source” , Phys. Rev.
Lett. 132, 023402 (2024).
2. Iwaguchi, S., Nishizawa, A., Chen, Y., Kawasaki,Y., Ishikawa, T., Kitaguchi, M., Yamagata, Y., Wu,
B., Shimizu, R., Umemura, K., Tsuji, K., Shimizu,
H., Michimura, Y., and Kawamura, S.:"Displacement-noise-free interferometericgravitational-wave detector using unidirectional
neutrons with four speeds", Phys. Lett. A 458,
128581 (2023).

4. Heacock, B., Fujiie, T., Haun, W.R.,.Henins, A.,
Hirota, K., Hosobata, T., Huber, M.G., Kitaguchi,
M., Pushin, D.A., Shimizu, H., Takeda, M.,
Valdillez, R., Yamagata, Y., and Young, A.R.:“Pendellosung interferometry probes theneutron charge radius, lattice dynamics, andfifth forces", Science 373, 1239-1243 (2021).

▲(a) Sodium LIDAR(b) Coherent Lyman-α resonance radiation source for ultra-slow muon generation(c) Laser inspection of infrastructure by courtesy of Shizuoka Pref. and Topcon Corp.
(d) Application of photonics control technology to plant cultivation

Newly Developed Supermirror Neutron Interferometer

5. Yamada, N., L., Hosobata, T., Nemoto, F., Hori, K.,
Hino, M., Izumi, J., Suzuki, K., Hirayama, M.,
Kanno, R., and Yamagata, Y.: “Application of
precise neutron focusing mirrors for neutronreflectometry: latest results and future
prospects” , J. Appl. Cryst. 53 (2020).

Member▲20

Ultrahigh Precision Machining,
Ultrahigh Precision Metrology, Aspherical Optics,
Production Technology, Neutron Optics

3. Aoki, H., Yuki, M., Shimizu, M., Hongoh, Y.,
Ohkuma, M., and Yamagata, Y.: "Agarose gel
microcapsules enable easy-to-prepare,picolitre-scale, single-cell genomics, yielding
high-coverage genome sequences", Sci. Rep. 12,17014–17026 (2022).

MemberNorihito Saito / Kiwamu Kase /Tomoki Matsuyama / Takafumi Sassa /Shigeharu Moriya / Takayo Ogawa /Katsushi Fujii / Kentaro Miyata / Masato Otagiri /Takeharu Murakami / Manabu Inukai /Tatsuya Shinozaki / Hiroshi Kasuga /Michio Sakashita / Katsuhiko Tsuno /Kei Morishita / Yasushi Kawata /Akihiro Tanabashi / Saki Miyajima /Hiroshi Matsutaka /Aya Kashifuku /Tomohiro Tsukihana / Norihiro Matsuyama /Noriko Kurose / Yoko Ono / Takeshi Matsumoto /Miyuki Nara

Keywords▲

Developing advanced optical components
by ultrahigh precision technology▲

Development of photonics control technology
for science and social issues▲

Keywords▲▲

FieldsEngineering,Interdisciplinary science and engineering

Koichiro Shirota / Yusuke Tajima /Yoshiyuki Takizawa / Tetsuya Aoyama /Noboru Ebizuka / Hiroyoshi Aoki /Takuya Hosobata / Masahiro Takeda

21

Advanced Photonics Technology Development Group

Neutron Beam Technology Team
Team Leader

Yoshie Otake

Advanced Photonics Technology Development Group

Advanced Manufacturing Support Team
Team Leader

D.Sci.

D.Eng.

▲

in steels▲

Publications

1. Otake, Y., Wakabayashi, Y., Takamura, M., Mizuta, M., andTakanashi, T.: “RIKEN Compact Neutron Source Systems
RANS Project” , Nuclear Physics News, Volume 33, Issue
2, Pages 17-21, (2023).
2. Hatsuda, M., Kawasaki, H., Yamakura, F., Taketani , A.,
Takanashi, T., Wakabayashi, Y., Otake, Y., Kamata, Y.,
Kurokawa, C., Ikeda, K., Shigenaga, A., Iesaki, T., andNagaoka, I.: “Effects of neutron radiation as cosmic
radiation on food resources” , Journal of Neutron
Research, 25, 41–46, (2023).

Research and development of compact neutron systemfor practical use at anytime, anywhere

Example of manufactured partsfor scientific apparatus and number of requests

The project of RIKEN accelerator-driven compact neutron system (RANS) has two main

It is inevitably required to devise and/or maintain variety of advanced researchdevelopment goals: the first is the realization of an evaluation and analysis system for

instruments and equipments to promote and support laboratories for wide ranges ofuse in the field of manufacturing, and the second is the development of non-destructive

research fields from fundamental to practical phases. The main duty of our team is toinspection techniques and equipment for preventive maintenance at infrastructure sites.

develop those instruments required by researchers, and also this duty should be

RANS-II with a total length of 5 m, which can be introduced into the onsite of

conducted consequently from concept design to manufacture through detailed design

manufacturing field, has been successfully developed. Neutron salt meter, RANS-μ forand instrumentation. Our team also deals with improvement and maintenance of working

outdoor use was successfully used to measure bridge salt density on national

scientific experimental equipments. For these purposes, we are constantly making efforts

1. Heacock, B., Fujiie, T., Haun, W.R.,.Henins, A.,
Hirota, K., Hosobata, T., Huber, M.G., Kitaguchi, M.,
Pushin, D.A., Shimizu, H., Takeda, M., Valdillez, R.,
Yamagata, Y., and Young, A.R.: "Pendellosunginterferometry probes the neutron charge radius,
lattice dynamics, and fifth forces", Science 373,
1239-1243 (2021).

highways, and inspection support performance catalogue of MILT. The transportable

to improve our design, manufacturing and engineering capabilities for rapid services.

RANS-III will finally be installed inside a tractor.

Production technology, Mechanical machining,
Laser machining, CAD/CAM/CAE, 3D printerPublications

2. Teshima, Y., Hosoya, Y., Sakai, K., Nakano, T., Tanaka, A.,
Aomatsu, T., Yamazawa, k., Ikegami, Y., and Watanabe,
Y.: “Development of Tactile Globe by Additive
Manufacturing” , Springer LNCS 12376, 419-426 (2020).

4. Oouchi, S., Yamazawa, K., and Secchi, L.: “Reproductionof Tactile Paintings for Visual Impairments Utilized
Three-Dimensional Modeling System and the Effect ofDifference in the Painting Size on Tactile Perception” ,Springer LNCS 6180, 527-533 (2010).

4. 大竹淑恵，水田真紀.: “中性子技術を用いたコンクリートの評価技術の最前線③小型中性子源の開発と維持管理への活用最前線，” , コンクリート工学. Vol.60，No.4，
pp.406-411 (2022).

5. Yamazawa, K., Hashizume, D., Nakao, A., Anzai, M.,
Narahara, H., and Suzuki, H.: “Proposal for Artificial
Bone Formation using Powder-layered
Manufacturing: Surface and Internal ChemicalComposition of Formed Artificial Bone” ,Transactions of the Japanese Society for Medical
and Biological Engineering Vol.47 No. 4, 359-365(2009).

5. Wakabayashi, Y., Yan, M., Takamura, M., Ooishi, R.,
Watase, H., Ikeda, Y., and Otake,Y.: “I Development of
neutron salt-meter RANS-μ for non-destructive inspectionof concrete structure at on-site use” , J. Neutron Res. 24,
no. 3-4, pp. 411-419 (2022).

▲

MemberMember▲22

Keywords

3. Yamazawa, K., Teshima, Y., Watanabe, Y., Ikegami,Y., Fujiyoshi, M., Oouchi, S., and Kaneko, T.:“Three-Dimensional Model Fabricated by Layered
Manufacturing for Visually Handicapped Persons
to Trace Heart Shape” , Springer LNCS 7383,
505-508 (2012).

3. Ikeda, S., Kobayashi, T., Otake, Y., Matsui, R., Okamura, M.,
and Hayashizaki, N.: “Fabrication and RF test of the 500
MHz-RFQ linear accelerator for a transportable neutron
source RANS-III” , J. Neutron Res. vol. 24, no. 3-4, pp.
249-259 (2022).

Tomohiro Kobayashi / Maki Mizuta /Takaoki Takanashi / Yasuki Okuno /Tomonori Fukuchi / Yasuo Wakabayashi /Abdul Muneem / Sho Otsuka

Engineering,Interdisciplinary science and engineering▲

Keywords

Accelerator-based compact neutron system,
Research and development of non-destructive inspection
for infrastructures, Detection of salt damage in theconcrete by promptgamma neutron activation analysis,
Visualization of water and air hole in concrete slabs,
Characterization of microstructure and texture evaluation

Fields▲Physics, Engineering,Interdisciplinary science and engineering▲▲

FieldsYutaka Yamagata

Takuya Hosobata / Shigeru Ikeda /Takeshi Fujimoto / Masahiro Takeda /The future imaging of compact neutron non-destructive test system on-site

Examples of manufactured components forscientific apparatuses and number of requests in FY2023

Masaharu Watanuki / Takayo Ogawa

23