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Xylene,JUNSEI CHEMICAL CO., LTD.,25165jis_J_E1-7,19/Mar/2024
Date of issue for the 1st edition : 25/Sep/2013
Date of revision : 19/Mar/2024

Safety Data Sheet

Section 1. Identification of the substance/mixture and of the company/undertaking
Product identifier:Product name: Xylene
Reference number(SDS):25165jis_J_E1-7
Product type：
Reagent
Details of the supplier of the safety data sheet
Manufacturer/Supplier: JUNSEI CHEMICAL CO., LTD.
Address: 1-6, Ohmano-cho, Koshigaya-shi, Saitama 343-0844, Japan
Division: Quality Assurance Department
Telephone number: +81-48-986-6161
FAX: +81-48-989-2787
e-mail address: shiyaku-t@junsei.co.jp

Section 2. Hazards identification
GHS classification and label elements of the product
Classification of the substance or mixture
PHYSICAL AND CHEMICAL HAZARDS
Flammable liquids: Category 3
HEALTH HAZARDS
Acute toxicity (Dermal): Category 4
Acute toxicity (Inhalation): Category 4
Skin corrosion/irritation: Category 2
Serious eye damage/eye irritation: Category 2
Carcinogenicity: Category 2
Reproductive toxicity: Category 1BSpecific target organ toxicity - single exposure: Category 1 (central nervous system, respiratory system, liver,kidney)Specific target organ toxicity - single exposure: Category 3 (Narcotic effects)
Specific target organ toxicity - repeated exposure: Category 1 (respiratory system, nervous system,
auditory organ)
ENVIRONMENT HAZARDS
Hazardous to the aquatic environment, short-term (acute): Category 2
Hazardous to the aquatic environment, long-term (chronic): Category 2(Note) GHS classification without description: Not classified/Classification not possible
Label elements

Signal word: Danger
HAZARD STATEMENT
H226-Flammable liquid and vapor
H312-Harmful in contact with skinH332-Harmful if inhaled
H315-Causes skin irritation
H319-Causes serious eye irritation
H351-Suspected of causing cancer

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Xylene,JUNSEI CHEMICAL CO., LTD.,25165jis_J_E1-7,19/Mar/2024
H360-May damage fertility or the unborn child
H370-Causes damage to organs
H336-May cause drowsiness or dizzinessH372-Causes damage to organs through prolonged or repeated exposure
H401-Toxic to aquatic life
H411-Toxic to aquatic life with long lasting effects
PRECAUTIONARY STATEMENT
Prevention
Obtain special instructions before use.
Do not handle until all safety precautions have been read and understood.
Avoid release to the environment.
Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking.
Keep container tightly closed.
Ground and bond container and receiving equipment.
Use explosion-proof electrical/ventilating/lighting equipment.
Use non-sparking tools.
Take action to prevent static discharges.
Do not breathe vapors.
Use only outdoors or in a well-ventilated area.
Wash contaminated parts thoroughly after handling.
Wear protective gloves/protective clothing/eye protection/face protection.
Use personal protective equipment as required.
Do not eat, drink or smoke when using this product.
Response
In case of fire: Use water mist, foam, dry powder, CO2 to extinguish.
Collect spillage.
Get medical advice/attention if you feel unwell.
IF exposed or concerned: Get medical advice/attention.
Call a POISON CENTER/doctor/physician if you feel unwell.
IF exposed or concerned: Call a POISON CENTER/doctor/physician.
IF INHALED: Remove person to fresh air and keep comfortable for breathing.
IF ON SKIN: Wash with plenty of soap and water.
IF ON SKIN (or hair): Take off immediately all contaminated clothing. Rinse skin with water or shower.
If skin irritation occurs: Get medical advice/attention.
Take off contaminated clothing and wash it before reuse.
IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if
present and easy to do. Continue rinsing.
If eye irritation persists: Get medical advice/attention.
Storage
Store in a well-ventilated place. Keep container tightly closed.
Keep cool.
Store locked up.
Disposal
Dispose of contents/container in accordance with local/national regulation.
Specific Physical and Chemical hazards
Flammable liquid. Vapor/air mixture may explode.

Section 3. Composition/information on ingredients
Mixture/Substance selection:
MixtureIngredient name:Xylene (Mixture of isomers)
Content (%):85
Chemical formula:C8H10

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Xylene,JUNSEI CHEMICAL CO., LTD.,25165jis_J_E1-7,19/Mar/2024
Chemicals No, Japan:3-3;3-60
CAS No.:1330-20-7
MW:106.17
EC No.:215-535-7
Ingredient name:Ethylbenzene
Content (%):15
Chemical formula:C8H10
Chemicals No, Japan:3-28;3-60
CAS No.:100-41-4
MW:106.17
EC No.:202-849-4
Note : The figures shown above are not the specifications of the product.

Section 4. First-aid measures
Descriptions of first-aid measures
General measures
Get medical advice/attention if you feel unwell.
Keep victim warm and quiet.
Call emergency medical service.
Effects of exposure (inhalation, ingestion or skin contact) to substance may be delayed.
IF INHALED
Remove person to fresh air and keep comfortable for breathing.
Give artificial respiration if victim is not breathing.
Administer oxygen if breathing is difficult.
Call a POISON CENTER/doctor/physician if you feel unwell.
IF ON SKIN (or hair）
Take off immediately all contaminated clothing. Rinse skin with water or shower.
Wash with plenty of soap and water.
If skin irritation or rash occurs: Get medical advice/attention.
If skin irritation occurs: Get medical advice/attention.
In case of burns, immediately cool affected skin for as long as possible with cｈild water.
Do not remove clothing if adhering to skin.
Remove and isolate contaminated clothing and shoes.
IF IN EYES
Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy
to do. Continue rinsing.
If eye irritation persists: Get medical advice/attention.
IF SWALLOWED
Rinse mouth.
Call a POISON CENTER/doctor/physician if you feel unwell.
Most important symptoms and effects, both acute and delayed(Symptoms when inhalation or ingestion)
Dizziness. Drowsiness. Headache. Nausea. Burning sensation. Abdominal pain.
(Symptoms when skin and/or eye contact)
Dry skin. Conjunctival redness of the eyes. Redness of the skin. Pain of the eyes.
Indication of any immediate medical attention and special treatment needed
Ensure that medical personnel are aware of the material(s) involved, and take precautions
to protect themselves.

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Section 5. Fire-fighting measures
Extinguishing media
Suitable extinguishing media
In case of fire, use water mist, foam, dry powder, CO2 to extinguish.
Unsuitable extinguishing media
Unsuitable extinguishing media data is not available.
Specific hazards arising from the substance or mixture
Containers may explode when heated.
Fire may produce irritating, corrosive and/or toxic gases.
Runoff from fire control or dilution water may cause pollution.
Advice for firefighters
Specific fire-fighting measures
Evacuate non-essential personnel to safe area.
Cool container with water spray.
Special protective equipment and precautions for fire-fighters
Wear fire resistant or flame retardant clothing.
Wear protective gloves/protective clothing/eye protection/face protection.
Firefighters should wear self-contained breathing apparatus with a full facepiece operated
in the positive pressure mode.

Section 6. Accidental release measures
Personnel precautions, protective equipment and emergency procedures
Keep unauthorized personnel away.
In case of contact with substance, immediately flush skin or eyes with running water for atleast 20 minutes.
Ventilate area until material pick up is complete.
Wear proper protective equipment.
PUBLIC SAFTY: Ventilate closed spaces before entering.
Do not touch or walk through spilled material.
Environmental precautions
Runoff to sewer may create fire or explosion hazard.
Vapors may form explosive mixtures with air.
Avoid release to headsprings, rivers, lakes, ocean and groundwater.
Methods and materials for containment and cleaning up
Absorb or cover with dry earth, sand or other non-combustible material and transfer to containers.
Use clean non-sparking tools to collect absorbed material.
All equipment used when handling the product must be grounded.
Preventive measures for secondary accident
Collect spillage.
Stop leak if you can do it without risk.
ELIMINATE all ignition sources (no smoking, flares, sparks or flames in immediate area).
Prevent entry into waterways, sewers, basements or confined areas.
Keep out of low areas.

Section 7. Handling and storage
Precautions for safe handling
Preventive measures(Exposure Control for handling personnel)
Do not breathe vapors.
(Protective measures against fire and explosion)
Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking.

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Ground and bond container and receiving equipment.
Use explosion-proof electrical/ventilating/lighting equipment.
Use non-sparking tools.
Take action to prevent static discharges.
(Exhaust/ventilator)
Exhaust/ventilator should be available.
(Safety treatments)
Avoid contact with skin.
Avoid contact with eyes.
Safety Measures
Obtain special instructions before use.
Do not handle until all safety precautions have been read and understood.
Use only outdoors or in a well-ventilated area.
Wear protective gloves/protective clothing/eye protection/face protection.
Use personal protective equipment as required.
When using do not eat, drink or smoke.
Any incompatibilities
Strong acids, Strong oxidizing agents should not be mixed with the chemicals.
Advice on general occupational hygiene
Wash contaminated parts thoroughly after handling.
Do not eat, drink or smoke when using this product.
Take off contaminated clothing and wash it before reuse.
Storage
Conditions for safe storage
Store in a well-ventilated place. Keep container tightly closed.
Keep cool. Protect from sunlight.
Store in accordance with local/national regulation.
Store locked up.
Container and packaging materials for safe handling data is not available.
Specific end use(s)See information in Section 7.1 and 7.2 for handling and storage recommendations. See
Section 8 for exposure controls and personal protection recommendations.

Section 8. Exposure controls/personal protection
Control parameters
Control value and Concentration standard value(Xylene (Mixture of isomers))
Japan control value 50ppm(Ethylbenzene)
Japan control value 20ppm
Adopted value(Xylene (Mixture of isomers))
JSOH(2001) 50ppm; 217mg/m3
ACGIH(2021) TWA: 20ppm (Eye & URT irr; hematologic eff; ototoxicity; CNS impair)(Ethylbenzene)
JSOH(2020) 20ppm; 87mg/m3 (skin)
ACGIH(2021) TWA: 20ppm (URT & eye irr; ototoxicity; kidney eff; CNS impair)[ACGIH] Notation(Xylene (Mixture of isomers))
OTO(Ethylbenzene)
OTO

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Xylene,JUNSEI CHEMICAL CO., LTD.,25165jis_J_E1-7,19/Mar/2024
Exposure controls
Appropriate engineering controls
Do not use in areas without adequate ventilation.
Eye wash station should be available.
Washing facilities should be available.
Individual protection measures
Respiratory protection
Wear respiratory protection.
Recommended respiratory protection：Gas mask(e.g. JIS T8152)
Hand protection
Wear protective gloves. Recommended material(s): viton
Inspect before use and replace worn or damaged gloves.
Contact the glove manufacturer for specific advice on glove selection and breakthroughtimes for your use conditions.
Chemical-resistant, impervious gloves complying with an approved standard (e.g. JIS T8116)
should be used.
Eye protection
Wear safety glasses with side-shields.
Wear eye/face protection.
Skin and body protection
Wear impervious clothing and boots in case of repeated or prolonged treatment.
Personal protective equipment for the body and skin should be selected based on the task
being performed and the risks involved.

Section 9. Physical and Chemical Properties
Information on basic physical and chemical properties
Physical state: Liquid
Color: Colorless
Odor: Characteristic odor
Odor threshold: 60 mg/m3(as Xylene (Mixture of isomers)); 8.7～870.0 mg/m3(as Ethylbenzene)
Melting point/Freezing point: <-25℃ (Xylene (Mixture of isomers))
Boiling point or initial boiling point: 139.1℃(Xylene (Mixture of isomers))
Boiling range data is not available.
Flammability (gases, liquids and solids): Ignitable
Lower and upper explosion limit/flammability limit:
Lower explosion limit: 1.0 vol %(Ethylbenzene)
Upper explosion limit: 6.7 vol %(Ethylbenzene)
Flash point: 29℃(Xylene (Mixture of isomers))
Auto-ignition temperature: 432℃(Ethylbenzene)
Decomposition temperature data is not available.
Self-Accelerating Decomposition Temperature/SADT data is not available.
pH data is not available.
Dynamic viscosity data is not available.
Kinematic viscosity data is not available.
Solubility:
Solubility in water: Insoluble
Solubility in solvent: Miscible with the usual organic solvents.
n-Octanol/water partition coefficient data is not available.
Vapor pressure data is not available.
Density and/or relative density: 0.860～0.870 g/ml (20℃)
Relative vapor density (Air=1) data is not available.
Relative density of the Vapor/air - mixture at 20℃ (Air = 1) data is not available.
Particle characteristics data is not available.

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Other information
Critical temperature data is not available.
Evaporation rate data is not available.
VOC data is not available.
Other information is not available.

Section 10. Stability and Reactivity
Reactivity
Runaway polymerization will not occur.
Chemical stability
Stable under normal storage/handling conditions.
Flammable.
Possibility of hazardous reactions
As a result of flow, agitation, etc., electrostatic charges can be generated.
Reacts with strong acids and strong oxidants.
Conditions to avoid
Contact with incompatible materials.
Open flames. Heating. Sparks.
Incompatible materials
Strong acids, Strong oxidizing agents
Hazardous decomposition products
Carbon oxides

Section 11. Toxicological Information
The product has not been subjected to toxicological testing. Refer to the available data on
the constituents.
Information on toxicological effects
Acute toxicity
Acute toxicity (Oral)[Product]Classification not possible (Insufficient data available or no data available).
[Data for components of the product][GHS Cat. Japan, base data](Xylene (Mixture of isomers))
rat LD50=3500～8800mg/kg (NITE risk assessment, 2008)(Ethylbenzene)
rat LD50=3500～4700mg/kg (AICIS IMAP, 2020)
Acute toxicity (Dermal)[Product]Category 4, Harmful in contact with skin
[Data for components of the product][GHS Cat. Japan, base data](Xylene (Mixture of isomers))
rabbit LD50=1700mg/kg (EPA Pesticide, 2005)(Ethylbenzene)
rabbit LD50=15400mg/kg (ACGIH, 2011)
Acute toxicity (Inhalation)[Product]Category 4, Harmful if inhaled8/13
Xylene,JUNSEI CHEMICAL CO., LTD.,25165jis_J_E1-7,19/Mar/2024[Data for components of the product][GHS Cat. Japan, base data](Xylene (Mixture of isomers))
vapor: rat LC50=6350～6700ppm/4hr (NITE Initial Risk Assessment Report, 2008)(Ethylbenzene)
vapor: rat LC50=4000ppm/4hr (OEL Documentations (JSOH), 2020)
mist: rat LC50=55mg/L/2hr (calc.: 27.5mg/L/4hr)(MOE Result of the initial environmental risk assessment of chemicals, 2015)
Irritant properties
Skin corrosion/irritation[Product]Category 2, Causes skin irritation[Data for components of the product][GHS Cat. Japan, base data](Xylene (Mixture of isomers))
rabbit : erythema, edema, necrosis (CERI/NITE Hazard Assessment Report, 2008)
Serious eye damage/irritation[Product]Category 2, Causes serious eye irritation[Data for components of the product][GHS Cat. Japan, base data](Xylene (Mixture of isomers))
rabbit : mild～moderate irritation (CERI/NITE Hazard Assessment Report, 2008)(Ethylbenzene)
rabbit : mild irritation (NITE Initial Risk Assessment Report, 2007 et al)
Sensitization
Respiratory sensitization[Product]Classification not possible (Insufficient data available or no data available).
[Data for components of the product]
No data available.
Skin sensitization[Product]Classification not possible (Insufficient data available or no data available).
[Data for components of the product]
No data available.
Germ cell mutagenicity[Product]Classification not possible (Insufficient data available or no data available).
[Data for components of the product]
No data available.
Carcinogenicity[Product]Category 2, Suspected of causing cancer[Data for components of the product][GHS Cat. Japan, base data](Ethylbenzene)
cat.2; IARC Gr. 2B (IARC, 2000)[IARC](Xylene (Mixture of isomers))
Group 3 : Not classifiable as to its carcinogenicity to humans(Ethylbenzene)
Group 2B : Possibly carcinogenic to humans

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Xylene,JUNSEI CHEMICAL CO., LTD.,25165jis_J_E1-7,19/Mar/2024[ACGIH](Xylene (Mixture of isomers))
A4(2021) : Not Classifiable as a Human Carcinogen(Ethylbenzene)
A3(2021) : Confirmed Animal Carcinogen with Unknown Relevance to Humans[EPA](Xylene (Mixture of isomers))
I; Data are inadequate for an assessment of human carcinogenic potential(1999)(Ethylbenzene)
Group D; Not classifiable as to human carcinogenicity(1986)[JSOH](Ethylbenzene)
Group 2B: The agents which are probably or possibly carcinogenic to humans
Reproductive toxicity[Product]Category 1B, May damage fertility or the unborn child[Data for components of the product][GHS Cat. Japan, base data](Xylene (Mixture of isomers))
cat. 1B; ATSDR, 2007
(Ethylbenzene)
cat. 1B; Recommendation of Occupational Exposure Limits (JSOH), 2021; ACGIH 7th, 2011 et al.
Specific target organ toxicity (STOT)
STOT-single exposure[Product]Category 1, Causes damage to organs
Category 3, May cause drowsiness or dizziness[Data for components of the product][cat.1][GHS Cat. Japan, base data](Xylene (Mixture of isomers))
liver, central nervous system, respiratory system, kidneys (CERI/NITE Hazard Assessment Report, 2008)[cat.3 (respiratory tract irritation)][GHS Cat. Japan, base data](Ethylbenzene)
respiratory tract irritation (ACGIH, 2011; AICIS IMAP, 2020)[cat.3 (narcotic effects)][GHS Cat. Japan, base data](Xylene (Mixture of isomers))
narcotic effect (CERI/NITE Hazard Assessment Report, 2008)(Ethylbenzene)
narcotic effect (ACGIH, 2011)
STOT-repeated exposure[Product]Category 1, Causes damage to organs through prolonged or repeated exposure[Data for components of the product][cat.1][GHS Cat. Japan, base data](Xylene (Mixture of isomers))
nervous system, respiratory system (CERI/NITE Hazard Assessment Report, 2008)(Ethylbenzene)
auditory organ, nervous system (JSOH OEL Documentations, 2020)10/13
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Aspiration hazard[Product]Classification not possible (Insufficient data available or no data available).
[Data for components of the product][cat.1][GHS Cat. Japan, base data](Xylene (Mixture of isomers))
cat. 1; hydrocarbon, kinematic viscosity=0.86(o-), 0.67(m-), 0.70(p-) mm2/s (25℃)(HSDB, Access on December 2014)(Ethylbenzene)
cat. 1; hydrocarbon, kinematic viscosity=0.63 mm2/s (40℃) (CLH Report, 2010)

Section 12. Ecological Information
The product has not been subjected to ecotoxicological testing. Refer to the available dataon the constituents.
Toxicity
Aquatic toxicity[Product]Category 2, Toxic to aquatic life
Category 2, Toxic to aquatic life with long lasting effects[Data for components of the product]
Hazardous to the aquatic environment, short-term (acute)[GHS Cat. Japan, base data](Xylene (Mixture of isomers))
Fish (rainbow trout) LC50=3.3mg/L/96hr (NITE Initial Risk Assessment, 2005)(Ethylbenzene)
Crustacea (bayshrimp) LC50＝0.42mg/L/96hr (NITE Initial Risk Assessment Report, 2007)
Hazardous to the aquatic environment, long-term (chronic)[GHS Cat. Japan, base data](Ethylbenzene)
Crustacea (Ceriodaphnia reticulata) NOEC=0.956mg/L/7days(MOE Result of the initial environmental risk assessment of chemicals, 2015)
Water solubility(Xylene (Mixture of isomers))
160 mg/L (25℃) (HSDB)(Ethylbenzene)
0.015 g/100 ml (20℃) (ICSC, 2007)
Persistence and degradability[Data for components of the product](Xylene (Mixture of isomers))
Not rapidly degradable [BOD_Degradation : 39% (NITE Initial Risk Assessment Report, 2005)](Ethylbenzene)
Not rapidly degradable [BOD_Degradation : 0% (MITI official bulletin, 1990)]
Bioaccumulative potential[Data for components of the product](Xylene (Mixture of isomers))
log Pow=3.16 (PHYSPROP DB, 2005)(Ethylbenzene)log Pow=3.15 (PHYSPROP DB, 2005)
Mobility in soil
Mobility in soil data is not available.
Other adverse effects
Ozone depleting chemical data is not available.

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Section 13. Disposal considerations
Description of waste residues and information on their safe handling and methods of disposal,
including the disposal of any contaminated packaging
Waste treatment methods
Avoid release to the environment.
Dispose of contents/container in accordance with local/national regulation.

Section 14. Transport Information
UN No., UN CLASS
UN Number or ID Number : 1307
UN Proper Shipping Name : XYLENESClass or division (Transport hazard class) : 3
Packing group : II
ERG GUIDE No.: 130
IMDG Code (International Maritime Dangerous Goods Regulations)
UN Number or ID Number : 1307
UN Proper Shipping Name : XYLENESClass or division (Transport hazard class) : 3
Packing group : II
IATA (Dangerous Goods Regulations)
UN Number or ID Number : 1307
UN Proper Shipping Name : XYLENESClass or division (Transport hazard class) : 3
Hazard labels : Flamm.liquid
Packing group : II
Environmental hazards
Marine pollutants (yes/no) : yes
Transport in bulk according to Annex II of MARPOL 73/78 and the IBC Code
Noxious Liquid Substances ; Cat. Y
Ethylbenzene; Xylene (Mixture of isomers)
MARPOL Annex V - HME (Harmful to the Marine Environment)
Reproductive toxicity: cat.1, 1A, 1B
Xylene (Mixture of isomers); Ethylbenzene
Specific target organ toxicity - repeated exposure: cat.1
Xylene (Mixture of isomers); Ethylbenzene
Hazardous to the aquatic environment - short-term (acute): cat.1
Ethylbenzene
Hazardous to the aquatic environment - long-term (chronic): cat.1, 2
Xylene (Mixture of isomers); Ethylbenzene

Section 15. Regulatory Information
Safety, health and environmental regulations/legislation specific for the substance or mixture
Labor Standards Act, Japan
Chemical substances or compounds (including alloys) causing disease (Regulation, Appended Table1-2-4-1)
Xylene (Mixture of isomers)
U.S. Toxic Substances Control Act (TSCA) Inventory
Chemicals listed in TSCA Inventory
100-41-4; 1330-20-7
All components are listed or exempted.

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Superfund Amendments and Reauthorizations Act (SARA), Title III
SARA 313 (TRI)
Ethylbenzene; Xylene (Mixture of isomers)
Other regulatory information
We are not able to check up the regulatory information with regard to the substances inyour country or region, therefore, we request this matter would be filled by yourresponsibility.
Regulatory information with regard to this substance in your country or in your region
should be examined by your own responsibility.
Ensure this material in compliance with federal requirements and ensure conformity to local
regulations.
Regulatory information in this section are limited to intentional ingredient(s), but does
not contain information on non-intentional ingredients or impurities which are not informedby supplier(s).
Chemical safety assessment
Advice on safe handling for this product can be found in sections 7 and 8 of this SDS.

Section 16. Other information
GHS classification and labellingH226-Flammable liquids, Category 3: H226 Flammable liquid and vapour
H312-Acute toxicity, Category 4: H312 Harmful in contact with skinH332-Acute toxicity, Category 4: H332 Harmful if inhaled
H315-Skin corrosion/irritation, Category 2: H315 Causes skin irritation
H319-Serious eye damage/eye irritation, Category 2: H319 Causes serious eye irritation
H351-Carcinogenicity, Category 2: H351 Suspected of causing cancer
H360-Reproductive toxicity, Category 1B: H360 May damage fertility or the unborn child
H370-STOT - single exposure, Category 1: H370 Causes damage to organs
H336-STOT - single exposure, Category 3, Narcotic effects: H336 May cause drowsiness or dizziness.
H372-STOT - Repeated exposure, Category 1: H372 Causes damage to organs through prolonged
or repeated exposure
H401-Hazardous to the aquatic environment, short-term (acute), Category 2: H401 Toxic to aquatic life
H411-Hazardous to the aquatic environment, long-term (chronic), Category 2: H411 Toxic toaquatic life with long lasting effects
References and sources for data
Globally Harmonized System of classification and labelling of chemicals, UN
Recommendations on the TRANSPORT OF DANGEROUS GOODS 22nd edit., 2021 UN
IMDG Code, 2022 Edition (Incorporating Amendment 41-22)
IATA Dangerous Goods Regulations (65th Edition) 20242020 EMERGENCY RESPONSE GUIDEBOOK (US DOT)
2024 TLVs and BEIs. (ACGIH)
JIS Z 7252 : 2019
JIS Z 7253 : 20192023 Recommendation on TLVs (JSOH)
Notification No. 0111-1 (January 11, 2022), Chemical Hazards Control Division, Industrial
Safety and Health Department, Labour Standards Bureau, MHLW in Japan
Supplier's data/information
Chemicals safety data management system "GHS Assistant" Version 4.27 (https://www.asahi-ghs.com/)
NITE Chemical Risk Information Platform "NITE-CHRIP"(https://www.nite.go.jp/en/chem/chrip/chrip_search/systemTop)
GHS Classification Guidance for Enterprises 2019 Revised Edition (Ver. 2.0) （Mar. 2020, METI)
Abbreviations and acronyms
SDS (Safety Data Sheet)
LD50 (Lethal Dose, 50％)

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LC50 (Lethal Concentration, 50％)
IARC (International Agency for Research on Cancer)
ACGIH (American Conference of Governmental Industrial Hygienists)
EPA (US Environmental Protection Agency)
NTP (US National Toxicology Program)
JSOH (Japan Society for Occupational Health)EU (European Union)
EC50 (Effective Concentration, 50％)
NOEC (No Observed Effect Concentration)
BOD (Biochemical Oxygen Demand)
COD (Chemical Oxygen Demand)
BCF (Bioconcentration Factor)anh (anhydride)
General Disclaimer
This data sheet was created based on the information we currently have and may be revised
according to new information. In addition, the precautions apply only to normal handling,
and in the case of special handling, please make adequate countermeasure to maintain yoursafety.
The data given here is based on current knowledge and experience. The purpose of this
Safety Data Sheet is to describe the products in terms of their safety requirements. The
data does not signify any warranty with regard to the products' properties.
The GHS classification data given here is based on current Japan official data (NITE
published in 2022).