ProgramSialoglyco2022
Organizers
Ken Kitajima (Nagoya University)
Hideharu Ishida (Gifu University)(Secretariat)
Chihiro Sato (Nagoya University)
Co-organizers
The Japanese Society of Carbohydrate Research (JSCR)
Institute for Glyco-core Research (iGCORE), Nagoya University
Bioscience and Biotechnology Center, Nagoya University
JSPS Core-to-Core Program
Support Organizers
The Japan Consortium for Glycobiology and Glycotechnology (JCGG)The Sialic Acids Society
PeriodFrom 5th to 8th September, 2022
Place
Toyoda Auditorium & Sympoion at Nagoya University
Address
Nagoya University
Furo-cho, Chikusa, Nagoya 464-8601, Japan
Fee
Regular persons
55,000 yen (65,000 yen)
Accompanying persons
20,000 yen (30,000 yen)Students
20,000 yen (30,000 yen)(
) after early birds up to 1st AugustInternet
Free Wi-Fi is available. Connect “nuwnet x1-guest”. PW is on your name card.
Please ask at the registration desk.
Welcome reception
5th September, 2022; 18:30-20:00 at Toyoda Auditorium
Banquet8th September, 2022; 19:00-21:00 at COURTYARD by MARRIOTT NAGOYA(1-17-6 Sakae, Naka-ku, Nagoya 460-0008, Japan; Tel: +81-52-228-2220)
Cost: 10,000 JPY/person
Bus transportation from Nagoya University to the place.

Access to Nagoya University
From Abroad
Haneda International
Airport (HND:Tokyo)ᲽExpress bus

ᲽᲫ 

ᲽᲫ 

Higashiyama-line(16 min)Shin-kansen(94 min)

NagoyaStationJRᲾᲫ 
HarukaShin-Osaka
Station(50 min)Shin-kansen
 min)
ᲾᲫ(49

ᲾᲫ 
ᲽᲬ 

(28 min)

ᲾᲬ 

ᲾᲬ 
ᲽᲬ 

ᲾᲬ 

Engineering and Science Building

ᲿᲫ 
ᲿᲬ 

ᲾᲬ 

ᲾᲬ 

ᲾᲬ 


ᲽᲬ From
Nagoya-Daigaku-stationᲽᲭ  meijo-subway
Exits
from
ᲽᲭ 
ᲾᲭ 

Noyori Conference Hall

ᲾᲭ 

ᲿᲭ 

ᲿᲭ 
ᲾᲭ 

ᲾᲭ 

IB Building

NagoyaᲿᲬ 
University

ᲿᲬ 

ᲽᲭ 

ᲽᲭ 

Meijo-line(2 min)ᲿNagoyaᲬ 
Meijo-line
ᲾKanayamaᲬ 
Daigaku(24 min)
StationStationNoyori Materials Science Laboratory
ᲾᲬ 
ᲾᲬ 
ᲿᲬ 
ᲾᲬ 

Ჾ
Წ  µ skyMeitetsu

CentrairᲽᲬAirport(NGO:Nagoya)ᲽᲬ Motoyama
Station

JR Narita ExpressᲾᲫ (75 min)ᲽᲫ 

Kansai InternationalᲽᲫ 
Airport (KIX:Osaka)
ᲽᲫ 

Ჿ

Ჾ

Tokyo
Station~70minᲾᲭ Conference placeen Belt

Monorail/
JR Line(25min)NaritaAirport (NRT:Tokyo)

ori 3

Shinagawa Shin-kansen(87 min)
StationKeikyu Line
(21min)Toyoda AuditoriumᲾᲭ 
Symposion

᳀Ჭ
ᲿᲭ 

ᲾᲭ 

Nagoya Univ. S.

ᲾᲮ 

ᲽᲮ 
ᲽᲮ 
ᲽᲮ 
ᲽᲮ 

NU Museum

Information Plaza

ᲾᲮ 

ᲾᲮ 
ᲾᲮ 

Yamate-dori 1

ᲿᲮ 

ᲽᲮ 

ᲽᲯ 

ᲿᲮ 

information

TEL 052-789-5111

Tennis Courts

ᲿᲯ 
ᲿᲯ 

ᲽᲯ 

for YYagoto
gotBToyoda Auditorium

PosterCloak

entrance

Symposion(Presentation)

entrance

Main entrance

Registration
desk
entrance

Information for Oral Presenters
Presentation time・Plenary Lecture: 50 min Talk, 10 min Discussion
・Invited Lecture: 15 min Talk, 5 min Discussion
・Oral Presentation: 10 min Talk, 2 min Discussion
・Young scientist presentation: 6 min Talk, 2 min Discussion (Please bring your poster
as well for poster session)
Oral presentations: Three-types
Type1: In person, Presenters are on-site
Type2: Presenters are on-line and live performing
Type3: Presenters are on-line, but in video. If possible, participating in live discussion only
# For Type 1 presenters, please use your own PC for presentation. Please save your file in
USB and bring it to the conference just in case for some PC troubles. Please connect to
ZOOM during your session via Wi-Fi.
# For Type2 or Type3 presenters, the video should be sent to the organizers beforehand.
The video preparation for Type2 is just in case for some troubles.
See the website in detail: https://www.agr.nagoya-u.ac.jp/~sialogly/
For all oral presenters in person
Please come to the PC-desk in the conference room before your session during breaktime. You can check if you come earlier.

Information for Poster Presenters
Poster display
From 6th to 8th September, 2022 (For 3 days)
You can put your poster from 5th September, 2022.
Poster presentation
We provide poster numbers on the board.
The board size is 180 cm (height) x 120 cm (width).
Please use the double-sided tape provided by the Sialoglyo2022 Office.
Discussion time
Odd:
Session I (14:00-14:30)
Session II (17:15-17:45)
Session III (13:30-14:00)
Even: Session I (14:30-15:00)
Session II (17:45-18:15)
Session III (14:00-14:30)

Scientific Advisory Board
Andrew J Bennet, Burnaby, Canada
Nicolai Bovin, Moscow, Russia
Paul Crocker, Dundee, UK
Philippe Delannoy, Lille, France
Jukka Finne, Helsinki, Finland
Rita Gerardy-Schahn, Hanover, Germany
Hideharu Ishida, Gifu, JapanMark von Itzstein, Gold Coast, Australia
Kay-Hooi Khoo, Taipei, Taiwan
Ken Kitajima, Nagoya, Japan
Jamey Marth, Santa Barbara, USA
James C Paulson, San Diego, USA
Yasuo Suzuki, Aichi, Japan
Sandro Sonnino, Milan, Italy
Garry Taylor, St Andrews, UK
Ajit Varki, San Diego, USA

Domestic Board Member, Sialoglyco 2022
Ken Kitajima (Nagoya University)
Chihiro Sato (Nagoya University)
Masaya Hane (Nagoya University)
Di Wu (Nagoya University)
Hideharu Ishida (Gifu University)
Hiromune Ando (Gifu University)
Akihiro Imamura (Gifu University)
Hidenori Tanaka (Gifu University)
Naoko Komura (Gifu University)
Tadanobu Takahashi (University of Shizuoka)
Akira Minami (University of Shizuoka)
Yuki Kurebayashi (University of Shizuoka)
Koichi Furukawa (Chubu University)

Sialoglyco 2022 Organizer
Ken Kitajima, Nagoya University
Hideharu Ishida, Gifu University

Sialoglyco 2022 Office
Chihiro Sato, Di Wu, Masaya Hane, Chikara Abe, andYoshiko Shibagaki (Secretary)
Bioscience and Biotechnology Center, Nagoya University
Chikusa, Nagoya 464-8601, Japan
Tel: +81-52-789-4297, FAX: +81-52-789-5228
E-mail: sialogly@agr.nagoya-u.ac.jp

Program

14:00-14:30

PosterdisplayO-5
O-6

Peng Wu (The Scripps Research Inst)
Yuko Naito-Matsui (Fujita Health Univ)

12:34-12:46

12:46-12:58

15:40-15:52

15:20-15:40

15:00-15:20

14:00-15:00

17:37-17:57

CE-2

CE-3

Chihiro Sato (Nagoya Univ)

Ken Kitajima (Nagoya Univ)

Welcome Reception

18:00-18:20

18:20-18:40

18:40-20:00

17:57-18:17

17:25-17:37

CE-1

Commemorative speech

Vered Padler-Karavani (Tel Aviv Univ)

17:30-18:00

17:05-17:25

17:00-17:30

16:45-17:05

Alice Yu (Chang Gung Univ)

V. Lokesh Battula (MD Anderson Cancer Ctr )Kei Kaneko (Chubu Univ)

Yusuke Ohmi (Chubu Univ)

Richard Jennemann (German Cancer Res Ctr)

IL-13

IL-12

O-10

IL-11

IL-10

O-13

IL-20

IL-19

IL-18

IL-17

Session: B-4 Young Researcher's Topics

Coffee BreakYuemei Lin (Delft Univ of Technology)

Chengcheng Huang (RIKEN)

Lucy K. Shewell (Griffith Univ)

Dirk J. Lefeber (Radboud UMC)

Kay-Hooi Khoo (Academia Sinica)

O-15

O-14

IL-23

IL-22

IL-21

Chair: Yann Guerardel (Univ of Lille), Ken Kitajima (Nagoya Univ)

Session B-3: Metabolism and Diseases II

Lunch

Jin-ichi Inokuchi (Tohoku Med Pharm Univ)

Sophie Groux-Degroote (Univ of Lille)

Martina Muhlenhoff (Hanover Med Sch)John S. Klassen (Univ of Alberta)

Simonetta Sipione (Univ of Alberta)

Y-11
Y-12

Daiki Kobayashi (Hokkaido Univ)

16:58-17:06

Poster Session II and Mixer

Jitske van Ede (Delft Univ of Technology)

16:50-16:58

17:15-19:00

Y-10

Y-9

Y-8

Y-7

Y-6

Y-5

Y-4

Y-3

Y-2

Y-1

Cristina Di Carluccio (Univ of Federico)Dani Zalem (Univ of Gothenburg)

Md Amran Howlader (Univ of Alberta)

Lareno L. Villones Jr. (Hokkaido Univ)

Larissa Schröter (Hanover Med Sch)

Sepideh Soukhtehzari (Univ of British Columbia)

Rina Hatanaka (Nagoya Univ)

Jing Wang (Griffith Univ)

Jiangming Zhong (Univ of Hong Kong)

Arno Fenske (Hanover Med Sch)

16:42-16:50

16:34-16:42

16:26-16:34

16:18-16:26

16:10-16:18

16:02-16:10

15:54-16:02

15:38-15:46

15:30-15:38

15:46-15:54

O-9

O-12

Chair: Naoko Komura (Gifu Univ), Di Wu (Nagoya Univ), Masaya Hane (Nagoya Univ)

Session: A-4 Sialic Acids in Gangliosides I

Coffee Break

Noriko Suzuki (Nagoya City Univ)

O-8

O-7

Emiel Rossing (Radboud Univ)
Akira Minami (Univ of Shizuoka)

14:54-15:30

14:42-14:54

14:30-14:42

IL-9

Go Hirai (Kyusyu Univ)

IL-8

Chair: Hideharu Ishida (Gifu Univ), Mark von Itzstein (Griffith Univ)
Elisa Fadda (Maynooth Univ)

14:10-14:30

Session: A-3 Chemistry and New Technology I

Chair: Koichi Furukawa (Chubu Univ), Philippe Delannoy (Univ of Lille)

16:16-16:45

Chair: Ken Kitajima (Nagoya Univ)

Coffee Break

Posterdisplay

12:32-13:30

13:50-14:10

O-4

Alba Silipo (Univ of Naples Federico II)

12:22-12:34

12:20-12:32

13:30-13:50

O-3

Simon Wisnovsky (Univ of British Columbia)

12:10-12:22

12:00-12:20

11:40-12:00

11:20-11:40

11:00-11:20

Poster Session I

IL-7

11:50-12:10

Coffee BreakJun Tsukimoto (Tokushima Univ)

Session: B-2 Sialic Acids in Gangliosides II

O-11

IL-16

Shinobu Kitazume (Fukushima Med Univ)

Arun Everest-Dass (Griffith Univ)

IL-14
IL-15

Amanda Lewis (Univ of California, San Diego)
Jamey D. Marth (SBP Medical Discovery Institute)

Chair: Koichi Furukawa (Chubu Univ), Philippe Delannoy (Univ of Lille)

10:24-11:00

10:12-10:24

10:00-10:12

Luncheon Seminar

IL-6

Takashi Angata (Academia Siica)

11:30-11:50

13:00-14:00

IL-5

Matthew Macauley (Univ of Alberta)
Herbert Hildebrandt (Hanover Med Sch)

11:10-11:30

16:04-16:16

David Crich (Univ of Georgia)

Session: A-2 Sialic Acids in Immunity
Chair: Takashi Angata (Academia Sinica), Matthew Macauley (Univ of Alberta)

Chair: Hiromune Ando (Gifu Univ)

PL-2

O-2

Commemorative event in memory of Profs. Roland Schauer,
Tamio Yamakawa, and Frederic A. Troy II

16:40-17:00

15:40-16:40

O-1

Yasuo Suzuki (Univ of Shizuoka)

10:32-10:44
Coffee Break

Robert P. de Vries (Utrecht Univ)

10:20-10:32

10:44-11:10

IL-4

9:40-10:00

IL-3

Yoichiro Fujioka (Hokkaido Univ)
Tadanobu Takahashi (Univ of Shizuoka)

9:40-10:00

IL-2

Takao Hashiguchi (Kyoto Univ)

9:20-9:40

10:00-10:20

9:20-9:40

IL-1

Victor Nizet (Univ of California, San Diego)

9:00-9:20

Chair: Yann Guerardel (Univ of Lille), Ken Kitajima (Nagoya Univ)
9:00-9:20

Oral

September 7, 2022 (Wednesday)

Chair: Tadanobu Takahashi (Univ of Shizuoka), Victor Nizet (Univ of California, San Diego)

PosterSession: B-1 Metabolism and Diseases I

Oral

September 6, 2022 (Tuesday)

Session: A-1 Sialic Acids in Infection

15:52-16:04

Coffee Break

15:30-15:40

PL-1

PosterPlenary Lecture 2

Ajit Varki (Univ of California, San Diego)

14:30-15:30

Chair: Rita Gerardy-Schahn (Hanover Med Sch)

Plenary Lecture 1

Registration

Opening Remarks

13:00-14:00

JSPS Core to Core Program meeting (9:00-13:00)

Oral

September 5, 2022 (Monday)

Posterdisplay

PosterSession C-2: Sialyltransferases in Diseases

Coffee BreakThomas Rexer (Max Planck Inst)

Ryo Okamoto (Osaka Univ)

Yuta Maki (Osaka Univ)

Michel Gilbert (HHTRC)

Christopher W. Cairo (Univ of Alberta)

Xuechen Li (Univ of Hong Kong)

Hiroshi Tanaka (Tokyo Inst Tech)

Chair: Hideharu Ishida (Gifu Univ), Mark von Itzstein (Griffith Univ)

O-19

O-18

O-17

O-16

IL-26

IL25

IL-24

Chihiro Sato (Nagoya Univ)

Yijuang Chern (Academia Sinica)

Session C-3: Glyco-genomics and Informatics

Poster Session III

Lunch

Kunio Kawanishi (Univ of Tsukuba)

John Yu (Chang Gung Univ)

Jianguo Gu (Tohoku Med Pharm Univ)

O-22

O-21

O-20

IL-28

IL-27

19:00-21:00

17:45-18:00

16:45-17:45

16:12-16:45

16:00-16:12

15:40-16:00

15:20-15:40

15:00-15:20

14:40-15:00

BanquetClosing Remarks

James C. Paulson (The Scripps Research Institute)

Chair: Ken Kitajima (Nagoya Univ)

Plenary Lecture 3

Coffee BreakHiroaki Tateno (AIST)

Hiren Joshi (Univ of Copenhagen)Anne Harduin-Lepers (Univ of Lille)

Kiyoko F. Aoki-Kinoshita (Soka Univ)

Toshiyuki Hayakawa (Kyushu Univ)

PL-3

O-23

IL-32

IL-31

IL-30

IL-29

Chair: Kiyoko F. Aoki-Kinoshita (Soka Univ), Anne Harduin-Lepers (Univ of Lille)

13:30-14:30

12:36-13:30

12:24-12:36

12:12-12:24

12:00-12:12

11:40-12:00

11:20-11:40

Chair: Rita Gerardy-Schahn (Hanover Med Sch), Chihiro Sato (Nagoya Univ)

10:48-11:20

10:36-10.48

10:24-10.36

10:12-10.24

10:00-10:12

9:40-10:00

9:20-9:40

9:00-9:20

Session: C-1 Chemistry and New technology 2

Oral

September 8, 2022 (Thursday)

Posterdisplay

Poster

Program at a glance

Unauthorized photography and audio/video recording are NOT permitted.

September 5, 2022 (Monday)
Oral

Poster

JSPS Core to Core Program meeting (9:00-13:00)

13:00-14:00
14:00-14:30

Registration

Opening Remarks
Plenary Lecture 1
Chair: Rita Gerardy-Schahn (Hanover Med Sch)

14:30-15:30

Ajit Varki (Univ of California, San Diego)

15:30-15:40

Coffee Break

PL-1

Plenary Lecture 2
Chair: Hiromune Ando (Gifu Univ)
15:40-16:40
16:40-17:00

David Crich (Univ of Georgia)

PL-2

Coffee BreakCommemorative event in memory of Profs. Roland Schauer,
Tamio Yamakawa, and Frederic A. Troy II
Chair: Ken Kitajima (Nagoya Univ)
17:00-17:30

Commemorative speech

17:30-18:00

Vered Padler-Karavani (Tel Aviv Univ)

CE-1

18:00-18:20

Chihiro Sato (Nagoya Univ)

CE-2

18:20-18:40

Ken Kitajima (Nagoya Univ)

CE-3

18:40-20:00

Welcome Reception

PosterdisplaySeptember 6, 2022 (Tuesday)
Oral

PosterSession: A-1 Sialic Acids in Infection
Chair: Tadanobu Takahashi (Univ of Shizuoka), Victor Nizet (Univ of California, San Diego)
9:00-9:20

Victor Nizet (Univ of California, San Diego)

IL-1

9:20-9:40

Takao Hashiguchi (Kyoto Univ)

IL-2

9:40-10:00

Yoichiro Fujioka (Hokkaido Univ)

IL-3

10:00-10:20

Tadanobu Takahashi (Univ of Shizuoka)

IL-4

10:20-10:32

Robert P. de Vries (Utrecht Univ)

O-1

10:32-10:44

Yasuo Suzuki (Univ of Shizuoka)

O-2

10:44-11:10

Coffee BreakSession: A-2 Sialic Acids in Immunity
Chair: Takashi Angata (Academia Sinica), Matthew Macauley (Univ of Alberta)
11:10-11:30

Matthew Macauley (Univ of Alberta)

IL-5

11:30-11:50

Herbert Hildebrandt (Hanover Med Sch)IL-6

11:50-12:10

Takashi Angata (Academia Sinica)

IL-7

12:10-12:22

Simon Wisnovsky (Univ of British Columbia)

O-3

12:22-12:34

Alba Silipo (Univ of Naples Federico II)

O-4

12:34-12:46

Peng Wu (The Scripps Research Inst)O-5

12:46-12:58

Yuko Naito-Matsui (Fujita Health Univ)

O-6

13:00-14:00

Luncheon Seminar

14:00-15:00

Poster Session I
Session: A-3 Chemistry and New Technology I
Chair: Hideharu Ishida (Gifu Univ), Mark von Itzstein (Griffith Univ)

15:00-15:20

Elisa Fadda (Maynooth Univ)

IL-8

15:20-15:40

Go Hirai (Kyusyu Univ)

IL-9

15:40-15:52

Emiel Rossing (Radboud Univ)

O-7

15:52-16:04

Akira Minami (Univ of Shizuoka)

O-8

16:04-16:16

Noriko Suzuki (Nagoya City Univ)

O-9

16:16-16:45

Coffee BreakSession: A-4 Sialic Acids in Gangliosides I
Chair: Koichi Furukawa (Chubu Univ), Philippe Delannoy (Univ of Lille)
16:45-17:05

Richard Jennemann (German Cancer Res Ctr)

IL-10

17:05-17:25

Yusuke Ohmi (Chubu Univ)

IL-11

17:25-17:37

Kei Kaneko (Chubu Univ)

O-10

17:37-17:57

V. Lokesh Battula (MD Anderson Cancer Ctr )IL-12

17:57-18:17

Alice Yu (Chang Gung Univ)

IL-13

PosterdisplaySeptember 7, 2022 (Wednesday)
Oral

PosterSession: B-1 Metabolism and Diseases I
Chair: Yann Guerardel (Univ of Lille), Ken Kitajima (Nagoya Univ)
9:00-9:20

Amanda Lewis (Univ of California, San Diego)

IL-14

9:20-9:40

Jamey D. Marth (SBP Medical Discovery Institute)

IL-15

9:40-10:00

Arun Everest-Dass (Griffith Univ)

IL-16

10:00-10:12

Shinobu Kitazume (Fukushima Med Univ)

O-11

10:12-10:24

Jun Tsukimoto (Tokushima Univ)

O-12

10:24-11:00

Coffee BreakSession: B-2 Sialic Acids in Gangliosides II
Chair: Koichi Furukawa (Chubu Univ), Philippe Delannoy (Univ of Lille)
Simonetta Sipione (Univ of Alberta)

IL-17

11:20-11:40

John S. Klassen (Univ of Alberta)

IL-18

11:40-12:00

Martina Muhlenhoff (Hanover Med Sch)IL-19

12:00-12:20

Sophie Groux-Degroote (Univ of Lille)

IL-20

12:20-12:32

Jin-ichi Inokuchi (Tohoku Med Pharm Univ)

O-13

11:00-11:20

12:32-13:30

Lunch (Photo session)

Session B-3: Metabolism and Diseases II
Chair: Yann Guerardel (Univ of Lille), Ken Kitajima (Nagoya Univ)
13:30-13:50

Kay-Hooi Khoo (Academia Sinica)

IL-21

13:50-14:10

Dirk J. Lefeber (Radboud UMC)

IL-22

14:10-14:30

Lucy K. Shewell (Griffith Univ)

IL-23

14:30-14:42

Chengcheng Huang (RIKEN)

O-14

14:42-14:54

Yuemei Lin (Delft Univ of Technology)

O-15

14:54-15:30

Coffee BreakSession: B-4 Young Researcher's Topics
Chair: Naoko Komura (Gifu Univ), Di Wu (Nagoya Univ), Masaya Hane (Nagoya Univ)
15:30-15:38

Arno Fenske (Hanover Med Sch)Y-1

15:38-15:46

Jiangming Zhong (Univ of Hong Kong)

Y-2

15:46-15:54

Jing Wang (Griffith Univ)

Y-3

15:54-16:02

Rina Hatanaka (Nagoya Univ)

Y-4

16:02-16:10

Sepideh Soukhtehzari (Univ of British Columbia)

Y-5

16:10-16:18

Larissa Schröter (Hanover Med Sch)Y-6

16:18-16:26

Lareno L. Villones Jr. (Hokkaido Univ)

Y-7

16:26-16:34

Md Amran Howlader (Univ of Alberta)

Y-8

16:34-16:42

Dani Zalem (Univ of Gothenburg)

Y-9

16:42-16:50

Cristina Di Carluccio (Univ of Federico)

Y-10

16:50-16:58

Jitske van Ede (Delft Univ of Technology)

Y-11

16:58-17:06

Daiki Kobayashi (Hokkaido Univ)

Y-12

17:15-19:00

Poster Session II and Mixer

PosterdisplaySeptember 8, 2022 (Thursday)
Oral

PosterSession: C-1 Chemistry and New technology 2
Chair: Hideharu Ishida (Gifu Univ), Mark von Itzstein (Griffith Univ)
9:00-9:20

Hiroshi Tanaka (Tokyo Inst Tech)

9:20-9:40

Xuechen Li (Univ of Hong Kong)IL25

9:40-10:00

Christopher W. Cairo (Univ of Alberta)

IL-26

10:00-10:12

Michel Gilbert (HHTRC)

O-16

10:12-10.24

Yuta Maki (Osaka Univ)

O-17

10:24-10.36

Ryo Okamoto (Osaka Univ)

O-18

10:36-10.48

Thomas Rexer (Max Planck Inst)O-19

10:48-11:20

IL-24

Posterdisplay

Coffee BreakSession C-2: Sialyltransferases in Diseases
Chair: Rita Gerardy-Schahn (Hanover Med Sch), Chihiro Sato (Nagoya Univ)
Yijuang Chern (Academia Sinica)

IL-27

11:40-12:00

Chihiro Sato (Nagoya Univ)

IL-28

12:00-12:12

Jianguo Gu (Tohoku Med Pharm Univ)

O-20

12:12-12:24

John Yu (Chang Gung Univ)

O-21

12:24-12:36

Kunio Kawanishi (Univ of Tsukuba)

O-22

12:36-13:30

Lunch

11:20-11:40

13:30-14:30

Poster Session III
Session C-3: Glyco-genomics and Informatics

Chair: Kiyoko F. Aoki-Kinoshita (Soka Univ), Anne Harduin-Lepers (Univ of Lille)
14:40-15:00

Toshiyuki Hayakawa (Kyushu Univ)

IL-29

15:00-15:20

Kiyoko F. Aoki-Kinoshita (Soka Univ)

IL-30

15:20-15:40

Anne Harduin-Lepers (Univ of Lille)

IL-31

15:40-16:00

Hiren Joshi (Univ of Copenhagen)

IL-32

16:00-16:12

Hiroaki Tateno (AIST)

O-23

16:12-16:45

Coffee BreakPlenary Lecture 3
Chair: Ken Kitajima (Nagoya Univ)
16:45-17:45

James C. Paulson (The Scripps Research Institute)

17:45-18:00

Closing Remarks

19:00-21:00

BanquetPL-3#Unauthorized photography and audio/video recording
are NOT permitted.

September 5, 2022
(Day 1)

Opening Remarks
14:00-14:30
Opening remark

Ken Kitajima (Nagoya University)

Welcome addressKenji Kadomatsu (Nagoya University)

Plenary Lecture 1
14:30-15:30
Chair：Rita Gerardy-Schahn (Hanover Medical School)

14:30

PL-01

"Serendipity in the Discovery of Vertebrate SialoglycanRecognizing Proteins: The Tip of an Iceberg?”
Ajit Varki
University of California, San Diego, USA[15:30-15:40 Break]

Plenary Lecture 2
15:40-16:40
Chair：Hiromune Ando (Gifu University)

15:40

PL-02

Recent advances in the chemistry of sialic acids andsialyl donors
David Crich
University of Georgia, USA[16:40-17:00 Coffee Break]Commemorative event in memory ofProfs. Roland Schauer, Tamio Yamakawa, and
Dr. Frederic A. Troy II
17:00-18:40
Chair：Ken Kitajima (Nagoya University)

17:00

Commemorative speech
Elfriede Schauer
Nissi Varki
University of California, San Diego, USA

Akemi Suzuki
Tohoku Medical and Pharmaceutical University, Japan

17:30

CE-01

Effects of immunological responses against glycosylated
biodevices in humans
Vered Padler-Karavani
Tel Aviv University, Israel

18:00

CE-02

Polysialylation in animals
Chihiro Sato
Nagoya University, Japan

18:20

CE-03

Sulfation of sialic acid is ubiquitous and essential for
vertebrate development
Ken Kitajima
Nagoya University, Japan

Welcome Reception
18:30-

September 6, 2022
(Day 2)

A-1: Sialic Acids in Infection
9:00Chair：Tadanobu Takahashi (Univ of Shizuoka) Victor Nizet (UCSD)

9:00

IL-01

Sialobiology of platelet-bacterial interactions in infection
Victor Nizet
University of California, San Diego, USA

9:20

IL-02

Glycan receptor and entry mechanism of mumps virus
Takao Hashiguchi
Kyoto University, Japan

9:40

IL-03

Mechanism of influenza A virus entry via calcium signalingmediated endocytosis
Yoichiro Fujioka
Hokkaido University, Japan

10:00

IL-04

Fluorescence imaging of viral sialidase activity by using
a new probe
Tadanobu Takahashi
University of Shizuoka, Japan

10:20

O-01

Sialyl-LewisX presented on N-glycans are conserved receptors
for influenza A viruses on the avian-mammalian interface
Robert P. de Vries
Utrecht University, The Netherlands

10:32

O-02

Significant role of host sialylated glycans in the infection andspread of SARS-CoV-2
Yasuo Suzuki
University of Shizuoka, Japan[10:44-11:10 Coffee Break]A-2: Sialic acids in Immunity
11:10Chair：Takashi Angata (Academia Sinica) Matthew Macauley (Univ of Alberta)

11:10

IL-05

Probing Siglec-glycolipid interactions
Matthew S. Macauley
University of Alberta, Canada

11:30

IL-06

Regulation of microglia and macrophage activity by thepolysialic acid-Siglec-16 axis is linked to survival of
glioblastoma patients
Herbert Hildebrandt
Hanover Medical School, Germany

11:50

IL-07

Molecular basis and role of Siglec-7 ligand expression on
chronic lymphocytic leukemia B cells
Takashi Angata
Academia Siica, Taiwan

12:10

O-03

Identification and functional characterization of ligands for the
Siglec family of glycan-binding immune receptors
Simon Wisnovsky
University of British Columbia, Canada

12:22

O-04

Fusobacterium LPS recognition of Siglec-7: a molecular view
Alba Silipo
University of Naples Federico II, Italy

12:34

O-05

Enhancing the anti-tumor efficacy of Bispecific T cell engagers
via cell surface sialoglycan editing
Peng Wu
The Scripps Research Institute, USA

12:46

O-06

Modulation of B cell receptor signaling in germinal center
Yuko Naito-Matsui
Fujita Health University, Japan[13:00-14:00 Luncheon Seminar]Poster session I
14:00-15:00
Odd: 14:00-14:30, Even: 14:30-15:00

A-3: Chemistry and New Technology 1
15:00Chair：Hideharu Ishida (Gifu Univ) Mark von Itzstein (Griffith Univ)

15:00

IL-08

Fine-tuning the spike: How the nature and topology of theglycan shield affect the SARS-CoV-2 S mechanism andviral infection
Elisa Fadda
Maynooth University, Ireland

15:20

IL-09

3-Exomethylene sialic acid disaccharides as substrate-typesialidaseinhibitors
Go Hirai
Kyusyu University, Japan

15:40

O-07

Improving the potency and selectivity of metabolic inhibition of
sialylation
Emiel Rossing
Radboud University Nijmegen, The Netherlands

15:52

O-08

The function of sialidase revealed by sialidase activity
imaging probe
Akira Minami
University of Shizuoka, Japan

16:04

O-09

N-Glycan structures of chicken trachea, lung, and colon
Noriko Suzuki
Nagoya City University, Japan[16:16-16:45 Coffee Break]A-4: Sialic acids in Gangliosides I
16:45Chair：Koichi Furukawa (Chubu Univ) Philippe Delannoy (Univ of Lille)

16:45

IL-10

Interrupting macrophage GSL metabolism triggers liver
inflammation and hepatocellular cancer growth in vivo
Richard Jennemann
German Cancer Research Center, Germany

17:05 IL-11

Analysis of proteins interacting with gangliosides in the lipid
rafts
Yusuke Ohmi
Chubu University, Japan

17:25

O-10

Roles of disialyl ganglioside-containing extracellular vesicles inmelanomas
Kei Kaneko
Chubu University, Japan

17:37

IL-12

Targeting ganglioside GD2 in breast cancer stem-like cells
V. Lokesh Battula
MD Anderson Cancer Center, USA

17:57

IL-13

GD2-targeted immunotherapy of cancer
Alice Yu
Chang Gung Memorial Hospital & Chang Gung University, Taiwan

September 7, 2022
(Day 3)B-1: Metabolism and Diseases I
9:00Chair：:Yann Guérardel (Univ of Lille) Ken Kitajima (Nagoya Univ)

9:00

IL-14

Digestion of epithelial sialoglycans in the bacterial vaginosis
microbiome
Amanda Lewis
University of California, San Diego, USA

9:20

IL-15

Sialyltransferase and sialidase enzymes in the onset andprogression of colitis
Jamey D. Marth
SBP Medical Discovery Institute, La Jolla, California, USA

9:40

IL-16

Glycosphingolipids are mediators of cancer plasticity throughindependent signalling pathways
Arun Everest-Dass
Griffith University, Australia

10:00

O-11

Non-classical glycosylation determines intracellular traffickingof APP
Shinobu Kitazume
Fukushima Medical University, Japan

10:12

O-12

Inhibition of in cellulo crystallization of human neuraminidase 1
and application for gene therapy of lysosomal storage disease
Jun Tsukimoto
Tokushima University, Japan[10:24-11:00 Coffee Break]B-2: Sialic acids in Gangliosides II
11:00Chair：Koichi Furukawa (Chubu Univ) Philippe Delannoy (Univ of Lille)

11:00 IL-17

Novel roles for gangliosides in neurodegeneration andneuroinflammation
Simonetta Sipione
University of Alberta, Canada

11:20 IL-18

Advances in mass spectrometry-based shotgun glycomics andapplications to sialic acid-binding lectins
John S. Klassen
University of Alberta, Canada

11:40 IL-19

Biosynthesis and pan-specific detection of 9-O-acetylated
gangliosides
Martina Mühlenhoff
Hanover Medical School, Germany

12:00 IL-20

Deciphering and targeting GD2 ganglioside O-acetylation
pathways in neuroectoderm-derived cancers
Sophie Groux-Degroote
University of Lille, France

12:20

O-13

Regulation of innate immune receptors by ganglioside GM3
Jin-ichi Inokuchi
Tohoku Medical and Pharmaceutical University, Japan[12:32-13:30 Lunch](Photo session)

B-3: Metabolism and Diseases II
13:30Chair: Ken Kitajima (Nagoya Univ) Yann Guérardel (Univ of Lille)

13:30 IL-21

Distinct O-GalNAc and O-Man glycomic landscapes of mousebrain carrying myriad sulfated sialylated glycotopes?
Kay-Hooi Khoo
Academia Sinica, Taiwan

13:50 IL-22

A tissue-specific view on sialic acid metabolism
Dirk J. Lefeber
Radboud University Medical Center, The Netherlands

14:10 IL-23

Serum Neu5Gc-glycoconjugates in diagnosis and monitoring ofbreast and ovarian cancer
Lucy K. Shewell
Griffith University, Australia

14:30 O-14

Can hepatocytes secrete free oligosaccharides?
-Possible mechanism for the occurrence of serum freeoligosaccharidesChengcheng Huang
RIKEN, Japan

14:42 O-15

The biosynthesis and catabolism of sialic acids in
non-pathogenic microbial community cultivated in thebioreactor under environmental conditions
Yuemei Lin
Delft University of Technology, The Netherlands[14:54-15:30 Coffee Break]B-4: Session for Young Researcher(Sponsored by JSPS Core-to-Core Program)
15:30Chair: Naoko Komura (Gifu Univ) Di Wu (Nagoya Univ) Masaya Hane (Nagoya Univ)

15:30 Y-1

Complement activation in asialo pregnancies
Arno Fenske
Hanover Medical School, Germany

15:38 Y-2

Regulation of uterine gland secretome sialylation andits implications in the pathogenesis of preeclampsia
Jiangming Zhong
The University of Hong Kong, Hong Kong

15:46 Y-3

Multiple human cancer cell lines produce Neu5Gc de novo
when cultured in serum-free, Neu5Gc-free media
Jing Wang
Griffith University, Australia

15:54 Y-4

Effects of a sialyltransferase ST8Sia6 in endoplasmic reticulumon malignant features
Rina Hatanaka
Nagoya University, Japan

16:02 Y-5

The different prognostic significance of polysialic acid,sialyltranferases and cd56 expression in tumor cells andlymphocytes identified in breast cancer
Sepideh Soukhtehzari
The University of British Columbia, Canada

16:10 Y-6

CASD1 and α2,8-sialyltransferases drive the formation of
9-O-acetylated sialoglycans
Larissa Schröter
Hanover Medical School, Germany16:18Y-7α2,3-Sialylation of α-dystroglycan O-mannosylated core M1
glycopeptides fine tunes its interaction with humanadhesion/growth regulatory Galectins
Lareno L. Villones Jr.
Hokkaido University, Japan

16:26

Y-8

Selective inhibitors of human neuraminidase enzymes in cell
migration, inflammation, and proliferation
Md Amran Howlader
University of Alberta, Canada

16:34

Y-9

Ganglioside recognition profile of the heat-labile enterotoxins
LT-IIB and LT-IIC from enterotoxigenic Escherichia coli
Dani Zalem
University of Gothenburg, Sweden

16:42

Y-10

Molecular details of N- and O-glycans recognition by Siglec-likeadhesins from Streptococcus gordonii and mitis
Cristina Di Carluccio
University Federico II, Italy

16:50

Y-11

The chemical diversity of the nonulosonic acids of a clinicalC. jejuni isolate and a related ΔCas9 mutant strain
Jitske van Ede
Delft University of Technology, The Netherlands

16:58

Y-12

Glycoscientific approaches to understand the ecology of avian
influenza viruses
Daiki Kobayashi
Hokkaido University, Japan

Poster session II & Mixer
17:15-19:00
Odd: 17:15-17:45, Even: 17:45-18:15

September 8, 2022
(Day 4)C-1: Chemistry and New Technology 2
9:00Chair：Hideharu Ishida (Gifu University) & Mark von Itzstein (Griffith University)

9:00

IL-24

Toward to chemical synthesis of polysialic acids
Hiroshi Tanaka
Tokyo Institute of Technology, Japan

9:20

IL-25

Chemical biology studies on bacterial pseudaminic acid
Xuechen Li
The University of Hong Kong, Hong Kong, China

9:40

IL-26

Inhibitors of the human neuraminidase enzymes as probes forglycobiology
Christopher W. Cairo
University of Alberta, Canada

10:00

O-16

Single-domain antibodies with engineered O-glycosylationsequons for site-specific conjugation through 9-azido-Nacetylneuraminic acid
Michel Gilbert
Human Health Therapeutics Research Centre, Canada

10:12

O-17

Chemical synthesis of an erythropoietin glycoform having asemisynthesized complex-type triantennary N-glycan andits biological evaluation
Yuta Maki
Osaka University, Japan

10:24

O-18

Study of the hydration property of sialyloligosaccharides onproteins using homogeneous glycoproteins prepared bytotal chemical synthesis
Ryo Okamoto
Osaka University, Japan

10:36

O-19

Synthesis of cytidine 5'-monophospho-N-acetylneuraminic acidThomas Rexer
Max Planck Institute for Dynamics of Complex Technical Systems, Germany[10:48-11:20 Coffee Break]C-2: Sialyltransferases in diseases
11:20Chair：Rita Gerardy-Schahn (Hanover Medical School) Chihiro Sato (Nagoya Univ)

11:20 IL-27

Downregulation of ST8SIA3 in Huntington’s disease
Yijuang Chern
Academia Sinica, Taiwan

11:40 IL-28

Polysialyltransferases in diseases
Chihiro Sato
Nagoya University, Japan

12:00 O-20

A novel regulatory mechanism for sialylation via the integrinFAK-PI4K-GOLPH3-ST axis
Jianguo Gu
Tohoku Medical and Pharmaceutical University, Japan

12:12 O-21

Identification of substrates of ST3GAL1 and the biologicalimpacts of their sialylation in cancer
John Yu
Chang Gung Memorial Hospital & Chang Gung University, Taiwan

12:24 O-22

Identification of sialic acid-containing molecules to establish a
new sialoglyco-biomarker for acquired cystic diseaseassociated renal cell carcinoma (ACD-RCC)
Kunio Kawanishi
Tsukuba University, Japan[12:36-13:30 Lunch]

Poster session III
13:30-14:30
Odd: 13:30-14:00, Even: 14:00-14:30(Poster Off: 14:30-14:40)

C-3 : Glyco-genomics and Informatics
14:40Chair ：Kiyoko F. Aoki-Kinoshita (Soka Univ) Anne Harduin-Lepers (Univof Lille)

14:40 IL-29

Adaptive evolution of the ST8SIA2 gene in anatomically modern
humansToshiyuki Hayakawa
Kyushu University, Japan

15:00 IL-30

Integration of data surrounding sialic acids through the
GlyCosmos Portal
Kiyoko F. Aoki-Kinoshita
Soka University, Japan

15:20 IL-31

Molecular and functional evolution of vertebrate alpha2,8sialyltransferases
Anne Harduin-Lepers
University of Lille, France

15:40 IL-32

Bioinformatic tools to dissect and simplify the informational
content of the glycome
Hiren Joshi
University of Copenhagen, Denmark

16:00 O-23

Integrated analysis of glycan and RNA in single cells
Hiroaki Tateno

National Institute of Advanced Industrial Science and Technology, Japan[16:12-16:45 Coffee Break]Plenary Lecture 3
16:45-17:45
Chair ：Ken Kitajima (Nagoya Univ)
16:45

PL-03

Exploiting Siglecs to suppress unwanted immune responses
James C. Paulson
The Scripps Research Institute, USA

Concluding Remarks
17:45Next Organizer’s address

Yann Guérardel (University of Lille)

Closing remark

Hideharu Ishida (Gifu University)

Poster Presentation(Display：September 6-8)

Poster session I, II, and III
P-01
(Y-7)

α2,3-Sialylation of α-dystroglycan O-mannosylated core M1
glycopeptides fine tunes its interaction with human adhesion/growth
regulatory Galectins
Lareno L. Villones Jr.a, Anna-Kristin Ludwigb, Hiroyuki Kumetaa,
Seiya Kikuchia, Rika Ochia, Tomoyasu Aizawaa, Shin-Ichiro Nishimuraa,
Hans-Joachim Gabiusb,†, Hiroshi Hinoua(aGraduate School of Life Science and Faculty of Advanced Life Science, Frontier
Research Center for Advanced Material & Life Science, Hokkaido University, Japan;
bPhysiological Chemistry, Department of Veterinary Sciences, Faculty of Veterinary

Medicine, Ludwig-Maximilians-University Munich, Germany;†Died on August 2, 2021)

P-02

Aging and sialylation changes in fibroblasts derived fromvarious tissues
Yoko Itakura, Norihiko Sasaki, Masashi Toyoda(Tokyo Metropolitan Institute of Gerontology, Japan)

P-03

Quantitative analysis of the polySia expression in brain during aging
Ayane Naramura1,2, Hirotake Nihei1,2, Masaya Hane1,2,3, Di Wu1,2,3, Ken
Kitajima1,2,3, Chihiro Sato1,2,3(1Biosci. Biotech. Center, Nagoya Univ., 2Grad. Sch. Bioagr. Sci., Nagoya
Univ., 3iGCORE, Nagoya Univ., Japan)

P-04

Analysis of free N-glycans in fish serum
Akinobu Honda, Junichi Seino, Tadashi Suzuki(Glycometabolic Biochemistry Lab., CPR, RIKEN, Japan）

P-05

Symbiotic Sialic Acid : An actor in symbiosis between anemonefish
and its host
Clément Delannoy1, Natacha Roux1, Chihiro Sato2, Ken Kitajima2,
Yann Guerardel1,3, Vincent Laudet1,4)（1UGSF UMR CNRS 8576, Université de Lille, France; 2iGCORE, Nagoya
University, Japan; 3 iGCORE, Gifu University, Japan; Marine Eco-Evo-Devo
Unit, OIST, Japan）

P-06

Expression of the human ST6GalNAc I to VI in Komagataella phaffii toelucidate their role in the synthesis of human milk oligosaccharides(HMOs)
Romane Breysse1, 2, Tom Verhaeghe1, Dries Van Herpe1, Michael
Muylaert1, Joeri Beauprez1,Wim Soetaert1, 2(1Inbiose N.V. 2University of Ghent, Belgium)

P-07(Y-11)

The chemical diversity of the nonulosonic acids of a clinical C. jejuni
isolate and a related ΔCas9 mutant strain
Jitske van Ede1, Chinmoy Saha2, Mark van Loosdrecht1, Rogier Louwen2 andMartin Pabst1(1Department of Biotechnology, Delft University of Technology, 2629 HZ Delft,
The Netherlands; 2Department of Medical Microbiology and Infectious Diseases,
University Medical Center Rotterdam, Rotterdam, The Netherlands)

P-08

Bifunctional sialidase/β-N-acetylgalactosaminidase from bifidobacteria
acting on Sda antigen/GM2
Shogo Kataoka1, Junya Kawasaki1, Keijiro Kamio2, Toshihiko Katoh3, Takane
Katayama3, Hisashi Ashida1,2(1Graduate School of Biology-Oriented Science and Technology, Kindai
University; 2Faculty of Biology-Oriented Science and Technology, Kindai
University; 3Graduate School of Biostudies, Kyoto University, Japan)

P-09

Transglycosylation activity of Bifidobacterium dentium amylosucrase
Te-Sheng Chang(Department of Biological Sciences and Technology, National University of Tainan,
Taiwan)P-10

Glycomic profiling of the gut microbiota of depressive mice
by Glycan-seq
Sunanda Keisham1, Lalhaba Oinam2, Fumi Minoshima2, Hirotaka
Yamagata3, Hiroaki Tateno1,2(1University of Tsukuba; 2National Institute of Advanced Industrial Science andTechnology (AIST), Tsukuba; 3Yamaguchi University, Japan)

P-11

Elucidating the mechanism of N-linked glycosylation in humanmalaria parasitesLọla Fagbami, Vasant Muralidharan(Center for Tropical and Emerging Global Diseases, Athens, Georgia, USA)

P-12
(Y-12)

Glycoscientific approaches to understand the ecology of avian influenza
viruses
Daiki Kobayashi1, Yuto Kikutani1, Rio Harada1, Masatoshi Okamatsu1,
Norikazu Isoda1,2, Yoshihiro Sakoda1,2, Takahiro Hiono1,2(1Laboratory of Microbiology, Department of Disease Control, Faculty of
Veterinary Medicine, Hokkaido University, Sapporo, Hokkaido, Japan;
2International Collaboration Unit, International Institute for Zoonosis Control,
Hokkaido University, Sapporo, Hokkaido, Japan)

P-13

Ezo red foxes and tanukis were naturally susceptible for the infection ofhighly pathogenic avian influenza viruses
Takahiro Hiono1,2, Daiki Kobayashi1, Rio Harada1, Atsushi Kobayashi3,4,
Tamami Suzuki3, Yuki Satake3, Keita Matsuno2,4, Mariko Sashika5,
Hinako Ban1, Maya Kobayashi1, Keisuke Aoshima3, Fumihito Takaya6,
Hiroko Fujita6, Norikazu Isoda1,2,4, Takashi Kimura3, Yoshihiro
Sakoda1,2,4(1Laboratory of Microbiology, Faculty of Veterinary Medicine, Hokkaido University;
2International Institute for Zoonosis Control, Hokkaido University; 3Laboratory ofComparative Pathology, Faculty of Veterinary Medicine, Hokkaido University;
4One Health Research Center (OHRC), Hokkaido University; 5Laboratory of Wildlife
Biology and Medicine, Faculty of Veterinary Medicine, Hokkaido University; 6Field
Science Center for Northern Biosphere (FSC), Hokkaido University)

P-14

Receptor structures that contribute to the propagation of human H1N1
influenza A viruses in embryonated chicken eggs
Sayaka Takase-Yoden1,2, Tomomi Ichimiya2, Masatoshi Okamatsu3, Takaaki
Kinoshita2,4, Daiki Kobayashi3, Osamu Ichii3, Naoki Yamamoto3,5, Yoshihiro
Sakoda3,6, Hiroshi Kida6, Hiroto Kawashima7, Kazuo Yamamoto8, Shoko
Nishihara1,2(1Glycan and Life Systems Integration Center (GaLSIC), Soka University, Japan;
2Graduate School of Science and Engineering, Soka University, Japan; 3Faculty of
Veterinary Medicine, Hokkaido University, Japan; 4Institute of Tropical Medicine,Nagasaki University, Japan; 5Tokyo Metropolitan Institute of Medical Science, Japan;
6International Institute for Zoonosis Control, Hokkaido University, Japan; 7Graduate
School of Pharmaceutical Sciences, Chiba University, Japan; 8Graduate School of
Medicine, Chiba University, Japan)

P-15

Development of MDCK cell lines expressing sialylated extended
N-glycan receptors for recent H3N2 influenza viruses
Chika Kikuchi1, Aristotelis Antonopoulos2, Andrew J. Thompson1, Stuart M.
Haslam2, and James C. Paulson1(1Departments of Molecular Medicine & Immunology and Microbiology, The Scripps
Research Institute, La Jolla, California, USA, 2 Department of Life Sciences, Imperial
College London, London, United Kingdom)

P-16

The SARS-CoV-2 N-terminal spike domain is primed to engage 9-Oacetylated 2-8-linked sialic acids
Ilhan Tomris1, Luca Unione2, Linh Nguyen3, Pouya Zaree1, Kim M.
Bouwman1, Lin Liu4, Zeshi Li1, María Ríos Carrasco1, Roosmarijn vander Woude1, Anne Kimpel1, Mirte Linthorst1, Enrico Verpalen1, Jelle A.
Fok1, Tom Caniels5, Rogier W. Sanders5,6, Balthasar A. Heesters1,
Roland J. Pieters1, Jesus Jimenez-Barbero2, John Klassen3, Geert-Jan
Boons1,4 and Robert P. de Vries1*(1Department of Chemical Biology & Drug Discovery, Utrecht Institute for
Pharmaceutical Sciences, Utrecht University, Utrecht, The Netherlands;
2CICbioGUNE, Basque Research & Technology Alliance (BRTA), Bizkaia, Spain;
3Department of Chemistry, University of Alberta, Edmonton, Canada;
4Complex Carbohydrate Research Center, University of Georgia, Athens, USA.
5Department of Medical Microbiology and Infection Prevention, Amsterdam University
Medical Centers, Location AMC, University of Amsterdam, Amsterdam,
The Netherlands; 6Department of Microbiology and Immunology, Weill Medical Centerof CornellUniversity, New York, USA)

P-17

Sialylated free-glycans in urine and their alterations in cancer
Ken Hanzawa1,2, Miki Tanaka-Okamoto2,3, Hiroko Murakami2,3, Yasuhide
Miyamoto2,4(1iGCORE, Gifu Univ, 2Dept Mol Biol, OICI, 3Dept Glyco-Oncol, OICI, 4Endocrin
Metab, Clin Lab OICI)

P-18

Gangliosides are novel modulators of extracellular vesicle secretion:
Dissecting structural requirements and glycan specificity
John Monyror1,2, Vaibhavi Kadam2, Luis C. Morales1, Diego Ordóñez1,
Elena Posse de Chaves1,2, Simonetta Sipione1,2(1Department of Pharmacology, 2Neuroscience and Mental Health Institute,
University of Alberta, Edmonton, AB., Canada)

P-19

GD3/GD2-positive glioma cell-derived exosomes enhance cancer
phenotypes
Mohammad A. Hasnat1, Qi Li1, Yuhsuke Ohmi2, Yukika Sugiura2, Farhana
Yesmin1,3, Robiul H. Bhuiyan1, Momoka Mizutani1, Yoshiyuki Kawamoto1,
Keiko Furukawa1, Koichi Furukawa1,3(1Department of Biomedical Sciences, Chubu University college of Life and Health
Sciences, Kasugai, 487-8501, Japan; 2Department of Clinical Engineering, Chubu
University college of Life and Health Sciences, Kasugai, 487-8501, Japan;
3Department of Molecular Biochemistry, Nagoya University Graduate School of
Medicine, Nagoya 466-0065, Japan)

P-20

Co-operation of ganglioside GD2 and integrins enhances in lipid rafts
malignant properties and signals in melanoma cells
Farhana Yesmin1,3*, Robiul H. Bhuiyan1, Yuhsuke Ohmi2, Orie Tajima1,

Kei Kaneko1, Tetsuya Okajima3, Keiko Furukawa1, Koichi Furukawa1,3(1Department of Biomedical Sciences, Chubu University College of Life and Health
Sciences, 2Department of Clinical Engineering, Chubu University College of Life and
Health Sciences 3Department of Molecular Biochemistry, Nagoya University Graduate
School of Medicine, Japan)

P-21

Analysis and prediction of sialoglycoconjugates in cancer cells
Masaya Hane1,2,3, Ken Kitajima1,2,3, Chihiro Sato1,2,3(1iGCORE, 2Grad. Sch. Bioagr. Sci, 3Biosci. Biotech. Center, Nagoya Univ.,
Japan)

P-22(Y-3)

Multiple human cancer cell lines produce Neu5Gc de novo
when cultured in serum-free, Neu5Gc-free media
Jing Wang1, Lucy K. Shewell1, Christopher J. Day1, Tiago Oliveira1, Daniel
Kolarich1 and Michael P. Jennings1*(1Institute for Glycomics, Griffith University, Gold Coast, Australia)

P-23

Identification of sulfated sialic acid-bearing glycoconjugates in cultured
cells expressing the sialate:O-sulfotransferases 1 and 2 genes
Sota Yamashita1,2, Di Wu1,2,3, Masaya Hane1,2,3, Chihiro Sato1,2,3, Ken
Kitajima1,2,3(1Grad. Sch. Bioagr. Sci, Nagoya Univ.; 2Biosci. Biotech. Center, Nagoya Univ.;
3iGCORE, Nagoya Univ., Japan)

P-24
(Y-6)

CASD1 and α2,8-sialyltransferases drive the formation of 9-O-acetylated
sialoglycans
Larissa Schröter, Malena Albers, Melanie Grove, Maike Hartmann, andMartina Mühlenhoff(Institute of Clinical Biochemistry, Hannover Medical School, Hannover, Germany)

P-25
(Y-4)

Effects of a sialyltransferase ST8Sia6 in endoplasmic reticulum on
malignant features
Rina Hatanaka1,2, Masaya Hane1,2,3, Di Wu1,2,3, Ken Kitajima1,2,3, Chihiro
Sato1,2,3(1Bioscience and Biotechnology Center, Nagoya University; 2Graduate School of
Bioagricultural Sciences, Nagoya University,3iGMED and iGCORE, Nagoya
University, Japan)

P-26
(Y-5)

The different prognostic significance of polysialic acid,sialyltransferases
and cd56 expression in tumor cells and lymphocytes identified in breast
cancer
Sepideh Soukhtehzari1, Richard B. Berish1, Ladan Fazli2, Peter H. Watson3,
and Karla C. Williams1*(1Faculty of Pharmaceutical Sciences, The University of British Columbia, Vancouver,
Canada; 2Pathology, Vancouver Prostate Centre, Vancouver, British Columbia,
Canada; 3BC Cancer, Victoria Centre, Victoria, British Columbia, Canada)

P-27

Effect of the lysosomal inhibitors and the proteasome inhibitoron the activity of the polysialyltransferases
Miho Ishikawa1,2, Masaya Hane1,2,3, Di Wu1,2,3, Ken Kitajima1,2,3, Chihiro
Sato1,2,3(1Biosci. Biotech. Center, Nagoya Univ., 2Bioagr. Sci. Nagoya Univ., 3iGCORE,
Nagoya Univ., Japan)

P-28

Promotion of sialylation of recombinant glycoprotein by tagging it with a
specific sequence recognized by a cargo receptor complex
Hirokazu Yagi1,2, Rino Yamada1, Shungo Adachi 3, Jun-ichi Furukawa4, Taiki
Saito1,5, Kengo Inutsuka1, Rio Nakano1, Saeko Yanaka1,2,5, Rena Honda2,5,

Kazuhiro Aoki2,6, Takuro Tojima7, Maho Yagi-Utsumi1,2,5, and Koichi Kato1,2,5(1Graduate School of Pharmaceutical Sciences, Nagoya City University, 2Exploratory
Research Center on Life and Living Systems (ExCELLS), National Institutes of Natural
Sciences, 3National Institute of Advanced Industrial Science and Technology (AIST),
4Institute for Glyco-core Research (iGCORE), Nagoya University, 5Institute for
Molecular Science, National Institutes of Natural Sciences, 6National Institute for Basic
Biology, National Institutes of Natural Sciences, 7 RIKEN Center for Advanced
Photonics)

P-29

Biological significance of α2,6-sialylation in early development of
medaka fish
Takayuki Omoto1,2, Di Wu1,2,3, Hisashi Hashimoto4, Masahiko Hibi4, Masaya
Hane1,2,3, Chihiro Sato1,2,3, Ken Kitajima1,2,3(1Grad. Sch. Bioagr. Sci., Nagoya Univ.; 2Biosci. Biotech. Center, Nagoya Univ.;
3iGCORE, Nagoya Univ.; 4Grad. Sch. Sci., Nagoya Univ., Japan)

P-30

Effects of acute stress on the polysialylated neural cell adhesion
molecule (polySia-NCAM) expression in mouse brain
Chikara Abe1,2, Yang Yi1,2, Masaya Hane1,2,3, Ken Kitajima1,2,3, Chihiro
Sato1,2,3(1Biosci. Biotech. Center, Nagoya Univ.; 2Grad. Sch. Bioagr. Sci., Nagoya Univ.
3iGCORE, Nagoya Univ.)

P-31

Biological significance of the polysialyltransferase St8sia2 in medaka,
Oryzias latipes
Tan Poh Ling1,2, Di Wu1,2,3, Masaya Hane1,2, Ken Kitajima1,2,3, Chihiro Sato1,2,3(1Biosci. Biotech. Center, Nagoya Univ, 2Grad. Sch. Bioagr. Sci., Nagoya Univ.,
3iGCORE, Nagoya Univ., Japan)

P-32

Significance of sialic acid 9-phospate synthase (SPS) and sialatepyruvate synthase (SPL)
Takahiro Nakagawa1,2, Di Wu1,2,3, Masaya Hane1,2,3, Chihiro Sato1,2,3, Ken
Kitajima1,2,3(1Biosci. Biotech. Center, Nagoya Univ., 2Grad. Sch. Bioagr. Sci., Nagoya Univ.,
3iGCORE, Nagoya Univ., Japan)

P-33

Substrate specificity and intracellular localization of the deuterostome
CMP-sialic acid synthetases
Misato Bessho1,2, Di Wu1,2,3, Masaya Hane1,2,3, Chihiro Sato1,2,3, Ken
Kitajima1,2,3(1Biosci. Biotech. Center, Nagoya Univ.; 2Grad. Sch. Bioagr. Sci., Nagoya Univ.;
3iGCORE, Nagoya Univ., Japan)

P-34

Study on the dynamic localization of the mouse CMP-sialic acidsynthetase
Mizuno Hidenori1,2,*, Hiromu Arakawa1,2,*, Di Wu1,2,3, Masaya Hane1,2,3, Chihiro
Sato1,2,3, Ken Kitajima1,2,3(1Grad. Sch. Bioagr. Sci, Nagoya Univ.; 2Biosci. Biotech. Center, Nagoya Univ.;
3iGCORE, Nagoya Univ. , Japan. *Equally contributed.)

P-35

Functional elucidation of the C-domain of vertebrate CMP-sialic acidsynthetase (CSS)
Sakura Toda1,2, Di Wu1,2,3, Masaya Hane1,2,3, Chihiro Sato1,2,3, Ken Kitajima1,2,3(1Grad. Sch. Bioagr. Sci.Naogya Univ., 2Biosci. Biotech. Center, Nagoya
Univ.,3iGCORE, Nagoya Univ., Japan)

P-36

The novel functions of N-domain and C-domain of CMP-sialic acidsynthetase at organism levelDi Wu1,2,3, Hisashi Hashimoto4, Masahiko Hibi4, Yasuhiro Kamei5, Kiyoshi
Naruse5, Chihiro Sato1,2,3, Ken Kitajima1,2,3(1Biosci. Biotech. Center, 2Grad. Sch. Bioagr. Sci., Nagoya Univ.; 3iGCORE,
Nagoya Univ.; 4Grad. Sch. Sci., Nagoya Univ.; 5Nat. Inst. Basic Biol.)

P-37
(Y-1)

Complement activation in asialo pregnancies
Arno Fenske1, Henri Wedekind1, Andreas Tiede2, Anja MünsterKühnel1, Birgit Weinhold1, Markus Abeln1(1Institute for Clinical Biochemistry, Hannover Medical School. 2Department of
Hematology, Hemostasis, Oncology, and Stem Cell Transplantation, Hannover
Medical School)

P-38

Complementary role of GlcNAc6ST2 and GlcNAc6ST3 in synthesis of
CL40-reactive sialylated and sulfated glycans in the pleural
mesothelium
Yoshiko Takeda-Uchimura1, Midori Ikezaki2, Tomoya O. Akama3, Kaho
Nishioka4, Yoshito Ihara2, Fabrice Allain1, Kazuchika Nishitsuji2 andKenji Uchimura1*(1Univ. Lille, CNRS, UMR 8576 - UGSF - Unité de Glycobiologie Structurale etFonctionnelle, Lille, France; 2Department of Biochemistry, 4Department of Obstetrics
and Gynecology, School of Medicine, Wakayama Medical University, Wakayama,
Japan; 3Department of Pharmacology, Kansai Medical University, Osaka, Japan)

P-39

Expression and function of sialyl Lewis X glycans on mouse regulatory
T cells
Kanae Ohishi, Shogo Nshida, Asaki Ishikura, Hirohito Abo, Hiroto Kawashima(Laboratory of Microbiology and Immunology, Graduate School of Pharmaceutical
Sciences, Chiba University)

P-40

Chemical Generation of Checkpoint Inhibitory T cell Engager (CiTEs) For
The Treatment of Cancer
Peter A. Szijja, Mikaela K. Ribib,†, Melissa A. Grayb,†, Calise Bahoua,João C. F. Nogueiraa, L Handyb, Carolyn R. Bertozzib*, Vijay Chudasamaa*(Stanford University, University College London)

P-41

Siglecs in the porcine oviduct and sialylated ligands on sperm:
potential role in sperm reservoir formation
Leonardo M. Molina1; Lauren E. Pepi2; Asif Shajahan2; Parastoo Azadi2;
Daniel B. McKim1; David J. Miller1(1Department of Animal Sciences, University of Illinois at Urbana-Champaign,
2Complex Carbohydrate Research Center, University of Georgia, USA)

P-42

The impact of sialylated glycocalyx of brain metastatic tumors on
immunosuppressive myeloid cells＊

Chin-Shan Fang, Tai-Yang Chen, Wen-Chin Yang, Hui-Ming Chen
(Agricultural Biotechnology Research Center, Academia Sinica, Taiwan)

P-43
(Y-2)

Regulation of uterine gland secretome sialylation and its implicationsin the pathogenesis of preeclampsia
Jiangming Zhong, Cheuk-Lun Lee, Philip C.N. Chiu
(Department of Obstetrics and Gynecology, LKS Faculty of Medicine,
The University of Hong Kong, Hong Kong SAR)

P-44

Interactions between the sialic acid-specific lectin Siglec-7 andacidic polysaccharides
Sayo Morishita1,2, Masaya Hane1,2,3, Hinano Komura1,2, Di Wu1,2,3,
Ken Kitajima1,2,3, Chihiro Sato1,2,3(1Biosci. Biotech. Center, Nagoya Univ., 2Grad. Sch. Bioagr. Sci., Nagoya Univ.,
3iGCORE, Nagoya Univ., Japan)

P-45

Disruption of Muc5b sialylation and Siglec-F signaling prevents
bleomycin-induced lung fibrosis
Naoko Hara, William J. Janssen, Christopher M. Evans(University of Colorado School of Medicine)

P-46

Carbohydrate-binding properties of a novel sialic acid binding siteon Siglec-9
Hinano Komura1,2, Yuki Asahina1,2, Atsushi Yoshimura1,2, Masaya Hane1,2,3,
Di Wu1,2,3, Ken Kitajima1,2,3, Chihiro Sato1,2,3(1Biosci. Biotech. Center, Nagoya Univ., 2Grad. Sch. Bioagr. Sci., Nagoya Univ.,
3iGCORE, Nagoya Univ., Japan)

P-47(Y-10)

Molecular details of N- and O-glycans recognition by Siglec-likeadhesins from Streptococcus gordonii and mitis
Cristina Di Carluccio1, Linda Cerofolini2, Antonio Molinaro1, Marco Fragai2,
Barbara A. Bensing3, Roberta Marchetti1, Alba Silipo1(1University Federico II, Department of Chemical Sciences, Via Cintia 4I, Naples, Italy;
2Magnetic Resonance Center (CERM), Via L. Sacconi 6, 50019 Sesto Fiorentino,
Italy: 3San Francisco Veterans Affairs Medical Center, San Francisco, USA)

P-48
(Y-9)

Ganglioside recognition profile of the heat-labile enterotoxins LT-IIb and
LT-IIc from enterotoxigenic escherichia coli
Dani Zalem1, Martin Juhas1,5, João P. Ribeiro4, Manuela Terrinoni2, Natalie
King-Lyons3, Michael Lebens2, Annabelle Varrot4, Anne Imberty4, Terry D.
Connell3, Susann Teneberg1(1Department of Medical Biochemistry and Cell Biology, Sahlgrenska Academy,
Institute of Biomedicine, University of Gothenburg, Gothenburg, Sweden;
2Department of Microbiology and Immunology, Sahlgrenska Academy, Institute of
Biomedicine, University of Gothenburg, Gothenburg, Sweden;
3Department of Microbiology & Immunology and The Witebsky Center for Microbial
Pathogenesis and Immunology, The Jacobs School of Medicine and Biomedical
Sciences, The University at Buffalo, State University of New York, Buffalo, USA;
4University Grenoble Alpes, CNRS, CERMAV, Grenoble, France
5Department of Pharmaceutical Chemistry and Pharmaceutical Analysis, Charles
University, Faculty of Pharmacy in Hradec Králové, Akademika Heyrovského 1203,
Hradec Králové, Czech Republic)

P-49

Ganglioside binding beta-trefoil lectin and its dual cellular function
Yuki Fujii1, Jun Koseki2, Kenichi Kamata3, Fujita Hideaki1, Ryuya Ishiwata4,
Ryuhei Hayashi4, Yasuhiro Ozeki4(1Nagasaki Int Univ, 2Nagoya Univ, 3KU Leuven Univ, 4Yokohama City Univ, Japan)

P-50

Evaluation of binding affinity of anti-glycan antibodies using thebiomolecular interaction analysis system
Kaito Hayakawa1,2, Masaya Hane1,2,3, Di Wu1,2,3, Ken Kitajima1,2,3,
Chihiro Sato1,2,3(1Grad. Sch. Bioagr. Sci, Nagoya Univ.; 2 Biosci. Biotech. Center, Nagoya Univ.;
3iGCORE, Nagoya Univ., Japan)

P-51

Binding analysis of pradimicin A with oligosaccharide motifs fromN-linked glycans
Masato Fujii,1 Makoto Ojika,1 Dai Akase,2 Misako Aida,2 Yasuhiro Igarashi,3
Yukishige Ito,4,5 Yu Nakagawa1,5,6(1Nagoya Univ., 2Hiroshima Univ., 3Toyama Prefectural Univ., 4Osaka Univ.,
5RIKEN, 6iGCORE, Japan)

P-52

Development of antibody-recruiting strategy using metabolic glycan
labeling to enhance immune responses
Hersa Milawati, Yoshiyuki Manabe, Kazuya Kabayama, Koichi Fukase(Department of Chemistry, Graduate School of Science, Osaka University, Japan)

P-53

Investigation of the reactivities of halogen-substituted bicyclic sialic aciddonors
Sakuma Yasutake1, Naoko Komura2, Taro Udagawa3, Hide-Nori
Tanaka2, Akihiro Imamura1,2, Hideharu Ishida1,2, Hiromune Ando2(1Dept. of Applied Bioorganic Chemistry, Gifu Univ., Japan, 2iGCORE, Gifu Univ.,
Japan, 3Faculty of Engineering, Gifu Univ., Japan)

P-54

Development of a fluorescent GD2 analog for single molecule imaging
Eriko Yamaguchi1, Naoko Komura1, Hide-Nori Tanaka1,2, Akihiro
Imamura1,2, Hideharu Ishida1,2, Sophie Groux-Degroote3, Martina
Mühlenhoff4, Hiromune Ando1,2(1Institute for Glyco-core Research (iGCORE), Gifu Univ., Japan,
2Depart. of Applied Bioorganic Chemistry, Gifu Univ., Japan, 3Univ.
Lille, CNRS, France, 4Institute of Clinical Biochemistry, Hannover
Medical School, Germany)

P-55

Development of a fluorescent ganglioside probe for single-molecule
imaging via late-stage sialylation
Maina Takahashi2, Naoko Komura1, Hide-Nori Tanaka1,2, Akihiro Imamura1,2,
Hideharu Ishida1,2, Kenichi G. N. Suzuki1,2 and Hiromune Ando1,2(1Institute for Glyco-core Research (iGCORE), Gifu University, Japan
2The United Graduate School of Agricultural Science, Gifu University, Japan)

P-56

Synthetic study of sialyl N-glycan: efficient glycosylation by controllingthe molecular aggregation
Kumpei Yano, Yoshiyuki Manabe, Asuka Shirakawa, Koichi Fukase(Department of Chemistry, Graduate School of Science, Osaka University)

P-57

Synthetic study of sialic acid-containing glycans derived from Nesseria
meningitidis W135
Hiro Yamamoto1, Naoko Komura2, Masahiro Kato1, Hide-Nori Tanaka2, Akihiro
Imamura1,2, Hideharu Ishida1,2, Hiromune Ando2(1Dept of Applied Bioorganic Chemistry, Gifu Univ., Japan, 2 iGCORE, Gifu Univ.,
Japan)

P-58

Efficient synthetic method for C3-modified sialoglycans and theirinhibitory activity for sialidases
Keiya Uezono, Risa Maeda, Hiroaki Matoba, Makoto Yoritate, Go Hirai(Graduate School of Pharmaceutical Sciences, Kyushu University)

P-59

Sialylgalactose analogue with exomethylene group acts as a substrate
but inhibits sialidase activity
Risa Maeda, Keiya Uezono, Ryo Fukazawa, Hiroaki Matoba, Makoto Yoritate,
Mikiko Sodeoka, Go Hirai(Graduate School of Pharmaceutical Sciences, Kyushu University, Japan)

P-60
(Y-8)

Selective inhibitors of human neuraminidase enzymes in cell migration,
inflammation, and proliferation
Md Amran Howlader, Christopher W. Cairo(University of Alberta, Alberta, Canada)

P-61

Investigating the CASD1 enzyme as a novel therapeutic target against
melanoma
Samuel J Heddes1, Thomas Litfin1, Alpesh Malde1, Lauren Hartley-Tassell1,
Martina Mühlenhoff2, Andrea Maggioni1 and Mark von Itzstein1(1Institute for Glycomics, Griffith University Gold Coast Campus, Queensland 4222,
Australia; 2Hannover Medical School, Hannover, Germany)

Sialoglyco 2022
Nagoya University
Chikusa, Nagoya 464-8601, Japan
TEL：81-52-789-4297
FAX：81-52-789-5228
September 2022