Data Collection ServiceC-Collection
X-ray diﬀraction data collection service at DLS, UKThe service for a protein X-ray diﬀraction data collection.
◇The mail-in service of Diamond Light Source (DLS), a synchrotron radiation facility in the UK, is used.

◇Customers can obtain diﬀraction data without leaving the laboratory.

◇No prolonged shutdowns. Can be used for urgent data acquisition.

Features1.

Easy application
Confocal Science takes care of all the procedures such as export of protein crystal
samples and application for use to DLS.
The customer is expected to send the necessary data and frozen protein crystals.

2.

Data acqusistion in a short time from application
The data will be delivered in as fast as about one month from the application.
DLS has no long-term shutdowns and is available year-round.

3.

High performance X-ray detector
High-performance X-ray detectors, PILATUS 6M or Eiger2 XE 16M are used for the data collection.
They are 2-dimensional single-photon counting pixel array type detectors, with high dynamic range andsignal-to-noise ratio.

4.

Conﬁdentiality
It is not necessary to disclose a protein name, etc.
Upon request, Confocal Science will ﬁx a conﬁdentiality agreement.

5.

Sending the crystal
Please store the frozen crystals in the designated location in the UNIPUCK and send them to Confocal Science by dryshipper. (Option: Confocal Science will freeze crystals. For this case, it is required to send the protein crystals and theharvest and cryoprotectant solutions.)

6.

Delivery of the data set
A set of raw data ﬁles output by PILATUS6M or Eiger2 XE 16M will be deliverd.
(Option: Confocal Science will perform scaling, evaluation and converting the data to F datawith statistical information. A customer can start structural analysis immediately after receivingthe data)

7.

Safe Overseas Transportation
A reliable courier carrier completes customs clearance to the UK prior to export.
The frozen crystals are transported to DLS quickly and reliably.

Process
UserApplication

ＣＳ

Export Procedures / Determination ofExport and Experimental Dates◇ Required information

Freez crystals

UserSend unfrozen crystals

User Send frozen crystals

ＣＳ Freez crystal (option)

UserＣＳ

Export to UKＤＬＳ

X-ray diﬀraction data collection

ＣＳ

Check the collected data set
Raw Data

ＣＳ① Sample name for descrimination (acronym)② Biological information (for the export
procedures, certificate of non-applicability
and the safety assessment for DLS)
③ cell constant, space group and maximum
resolution (if known)◇ Data collection
Confocal Science will monitor the status ofdata collection during diffraction
experiments in real time. Additional datacollection is available upon request (extracharge).

ＣＳ Scaling (option)

Deliver the data set※

Protein crystals will not be returned usually.

Application

1 Contact us

2 Scheduling

3 Application
One month before
the experimentaldateOption (extra fee)
●Cryo-cooling the protein crystals●Scaling the collected data set

Contact
Confocal Science Inc.
Musashino Bld. 2F, Fukasawa 5-14-15
Setagaya-ku, Tokyo 158-0081 JapanTEL 03-5809-1561 FAX 03-6411-6261

MAIL：info@confsci.co.jp
Website: http://www.confsci.co.jp/●The contents of this catalog are subject to change without notice.（Ver. 2406)

4 DataCollection