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MI were younger (59.9+/-10.9 years) than controls (66.1+/-10.0 years) (P=0.004). The prevalence of smokers was higher in thecontrol group (35.9% vs. 30.2%, P=0.015). Unadjusted genotype and allele frequencies were similar between the 2 groups. We
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P=0.003, and OR=1.41, 95% CI: 1.01-1.98, P=0.04, respectively). However, no significant association was found between
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1.02-1.90, P=0.04, respectively). Genetic variation of VEGF is associated with increased risk of MI.Embryonic stem cellderived hepatocyte-like cells as a platform for drug discovery. One of the most promising strategies for drug discovery is the useof mammalian stem cells to generate functional cells that can then be used as a platform for high-throughput screening of drugcandidates. Among various stem cells, embryonic stem cells (ESCs

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