International Atomic Energy Agency
Department of Technical Cooperation
AndNuclear Medicine and Diagnostic Imaging Section
Division of Human Health
RAS6074
Improving Quality of Life of Cancer Patients through Streamlined and Emerging
Therapeutic Nuclear Medicine Techniques

Workshop and Final Coordination Meeting on Nuclear
Medicine Techniques in Neurological Diseases II (ICNMP-PA)
June 26-30, 2017
Multimedia Hall, the Center of Medical Innovation and Translational
Research building 1F,
Osaka University Graduate School of Medicine,
Osaka, Japan

Local Course Director
HATAZAWA, Jun
Osaka University Graduate School of Medicine
Department of Nuclear Medicine and Tracer Kinetics
565-0871 OsakaJapan
Tel: 81668793461
Fax: 81668793469
E-mail: hatazawa@tracer.med.osaka-u.ac.jp

IAEA TECHNICAL OFFICER
Mr. PASCUAL Thomas NB
Section of Nuclear Medicine and Diagnostic Imaging
Division of Human HealthInternational Atomic Energy Agency, Vienna International Centre, PO Box
100, 1400 Vienna, Australia

IAEA PROJECT MANAGEMENT OFFICER:
Mr SHAKHASHIRO, Abdulghani
Asia and the Pacific Section 1
Division for Asia and the Pacific
Department of Technical Cooperation
A.Shakhashiro@iaea.org

PROGRAM
Monday 26 June 2017
09:00-09:30

Opening remarks
Pre-Course Evaluation

Pascual, Thomas(Technical Officer,IAEA)
Shakhashiro,Abdulghani(IAEA ProgrammeManagement Officer)
Prof. Jun Hatazawa
Course Director

SESSION 1Chair
GIESEL, Frederik
University Hospital Heidelberg
Department of Nuclear Medicine Clinic of Radiology
69120 Heidelberg
Germany
Pascual, Thomas (Technical Officer, IAEA)
Instrumentation of SPECT/CT, PET/CT, and PET/MR
09:30- 10:30
ILO: Review and discuss the importance of Instrumentations
used in SPECT and PET combined with CT or MR for
Neurological Imaging using Nuclear Medicine techniques

10:30-11:30

Handling computer software, modeling, and image analysis
ILO: Review and discuss the importance of handlingcomputer software, modeling, and image analysis for
Neurological Imaging using Nuclear Medicine techniques

11:30:12:30

Brain anatomy and molecular imaging
ILO:
1.Discuss the role of Brain Anatomy and Molecular Imaging
in relation to practice of nuclear medicine
2. Integrate the concepts discussed in relation to bestpractices of brain imaging using nuclear techniques.

Dr. Seiichi Yamamoto
Nagoya University,
Nagoya, Japan

Dr. Masanori Ichise
National Institute ofRadiological Sciences,Chiba, Japan

Dr. GIESEL, Frederik
University Hospital
Heidelberg
Department ofNuclear Medicine
Clinic of Radiology
69120 Heidelberg
Germany

12:30-13:30

Lunch Break

13:30-14:00

Public special lecture:
Introduction of “Quantum Scalpel“ Project and future
perspectives (tentative).

Dr. Toshio Hirano
President, Quantum
and Radiological
Science andTechnology, Chiba,Japan

14:00-14:45

Radiopharmaceuticals in brain imaging: SPECT andSPECT/CT.

Dr. Hiroshi Toyama
Fujita HealthUniversity, Nagoya,
Japan

ILO:
1. Recognize the significance of radiopharmaceuticals
used in SPECT/CT brain imaging.
2. Integrate the concepts of radiopharmaceuticals inbrain imaging within the context of best practices ofthe nuclear technology on the brain imaging
14:45-15:30

Radiopharmaceuticals in brain imaging: PET/CT and PET/MRILO:

Dr. Tadashi Watabe,Osaka University,Osaka, Japan

1. Summarize the Radiopharmaceuticals used in
PET/CT or PET/MR brain imaging
2. List examples of diseases that can be diagnosed by
FDG-PET scans.
3. Discuss principal differences between FDG and nonFDG agents in brain imaging.
16:00-16:30

SPECT and PET in stroke: Theory and case presentation
ILO:

1. Discuss the utilization of SPECT and PET imaging
modalities in the evaluation of ischemic stroke
2. Determine the limitations SPECT and PET imaging
technique in stroke in relation to CT and MR

Dr. Eku Shimosegawa
Osaka University,Osaka, Japan16:30-17:00

Boron Neutron Capture Therapy and Nuclear Medicine

Dr. Koji Ono
Kyoto University

ILO: understand the principle of boron neutron capture
therapy and importance of nuclear medicine imaging incancer patients.

End of session 1
17:30- Welcome Reception(Venue: Minerva, Second floor of Ginkgo Kaikan)
Hosted by Osaka University and IAEA

Tuesday, 27 June 2017
SESSION 2
Chair:GIESEL, Frederik
University Hospital Heidelberg
Department of Nuclear Medicine Clinic of Radiology
69120 Heidelberg
Germany
Shakhashiro, Abdulghani(IAEA Programme Management Officer)
09:00-10:00
Alzheimer’s Disease
ILO:
1. Understand the pathophysiology of Alzheimer’sdisease.

Dr. Hiroshi Matsuda
National Center of
Neurology andPsychiatry, Tokyo,Japan

2. Discuss the risk factors of Alzheimer’s disease.
3. Discuss the role of nuclear medicine imaging in
Alzheimer’s dieases
10:00-11:00

Movement Disorder
ILO:
1. Understand the pathophysiology of Movementdisorders.

Dr. Etsuko
Imabayashi
National Center ofNeurology andPsychiatry, Tokyo,Japan

2. Discuss the utilization of nuclear medicine imaging
modalities in the evaluation of movement disorders
11:00:12:00

Brain tumor
ILO:
1. Understand the pathophysiology of Movement

Dr. Frederik Giesel
IAEA Experts

disorders.
2. Discuss the utilization of nuclear medicine imaging
modalities in the evaluation of movement disorders
12:00-14:00

Lunch Break

14:00-14:30

Seizures
ILO:
1. Understand the pathophysiology of seizures

Dr. Daichi Sone
National Center of
Neurology andPsychiatry, Tokyo,Japan

2. Discuss the risk factors
3. Discuss the role of nuclear medicine imaging inseizures
14:30-15:00

Pediatric Nuclear Medicine
ILO:

Dr. Mayuki Uchiyama
The Jikei MedicalUniversity

1. Understand the pathophysiology/ classification ofdifferent paediatric brain tumours and neurologicaldisorders
2. Discuss the role of nuclear medicine imaging in
paediatric brain imaging
15:00-15:30

Brain Death
ILO:
Discuss the role of nuclear medicine imaging
techniques in brain death imaging

16:00-16:30

Brain Trauma
ILO:
Discuss the role of nuclear medicine imaging in brain
traumaDr. Toshimitsu
MomoseInternational
University of Healthand Welfare, Chiba,Japan
Dr. Toru Shiga
Hokkaido University,Sapporo, Japan

16:30-17:00

SPECT and PET in Psychiatry
ILO:
1. Understand the pathophysiology/ classification ofdifferent psychiatric cases in relation to brain imaging
2. Discuss the role of nuclear medicine imaging inpsychiatry

End of session 2

Dr. Tetsuya Suhara
National Institute ofRadiological
Sciences, Chiba,Japan

Wednesday, 28 June 2017
SESSION 3
Chair:
GIESEL, Frederik
University Hospital Heidelberg
Department of Nuclear Medicine Clinic of Radiology
69120 Heidelberg
Germany
9:00-10:00
Statistical Parametric Analysis in Nuclear Medicine
ILO:

Dr. Hiroki Kato
Osaka University

Review and understand basic concept of statisticalparametric analysis used in SPECT and PET combined withCT or MR for Neurological Imaging using Nuclear Medicine
techniques

10:00-10:30

Normal data base for statistical parametric analysis

11:00-12:00

ILO: understand the importance of normal data basefor statistical parametricHandling software and data analysis

Dr. Hiroki Kato
Osaka University
Dr. Hiroki Kato
Osaka University

12:00-13:00

Lunch BreakLunch buffet hosted by Osaka University(Venue: Resting area in front of Multimedia Hall)

13:00-15:30Review Meeting for Counterparts·Presentation of country reports (5minutes each)·Collection of country reports·Summarization of report

IAEA, Participant
One Participant fromeach country willneed to present theproject achievements,
lessons learned andway forward andprepare the meetingfinal report forRAS6074.
Please coordinate
who will present fromyour country
16:00-17:30

Technical visit: Tenma-Tenjin PET centerEnd of session 3

Thursday 29 June 2017
SESSION 4:
Chair:

09:00-12:00

Case presentation (including report writing and groupdiscussion):
ILO:

Dr. Jun Hatazawa
Dr. Tadashi WatabeOsaka University,
Osaka, Japan

1. Describe appropriate ways of report writing inneurological cases with CT and/or MR interpretation
2. Discuss the role of Brain Imaging using actual cases
for image interpretation and its relevance in clinicalpractice
12:00-14:00

Lunch Break

14:00-17:00

Parametric image analysis of brain images (includingsoftware practice):
ILO:
1. Enumerate and discuss the different Parametricimage analysis used in brain imaging

END OF SESSION 4

Dr. Hiroki Kato
Osaka University,
Osaka, Japan
Dr. Tadashi Watabe
Osaka University,
Osaka, Japan

Friday 30 June 2017
SESSION 5
CHAIR:GIESEL, Frederik
University Hospital Heidelberg
Department of Nuclear Medicine Clinic of Radiology
69120 Heidelberg
Germany
9:00-10:00

Nuclear Medicine Theranostics (1)10:00-11:00

ILO:
Understand the concept of nuclear medicine
theranostics, production of radionuclides, andapplication
Nuclear Medicine Theranostics (2)ILO:
Understand alpha-emitting radionuclide based therapyof brain tumors and prostate cancer

11:00-11:30

Future application of Brain Nuclear Medicine
ILO:
1.Describe and explain future application of brain
imaging using nuclear medicine techniques
2.Explore possibilities on how these newer
technologies will have a positive impact on nuclear
medicine practice

11:30-12:00

Closing Remarks
Post course evaluation

Dr. Mitsuaki Tatsumi
Osaka University,Osaka, Japan
Dr. Jun Hatazawa,
Osaka University,Osaka, Japan
Dr. Frederik Giesel
IAEA Expert

Dr. HATAZAWA, Jun
Osaka University
Graduate School ofMedicine
Department of
Nuclear Medicineand Tracer Kinetics
Osaka

Pascual, Thomas(Technical Officer,IAEA)
Shakhashiro,Abdulghani(IAEA ProgrammeManagementOfficer)
Prof. Jun Hatazawa
Course Director