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Takahashi T, Suzuki H, Imai T, Shibata S, Tabuchi Y, Tsuchimoto K, Okano H, Hibi T. Musashi-1
post-transcriptionally enhances phosphotyrosine-binding domain-containing m-Numb protein expression inregenerating gastric mucosa. PLoS One. 8(1):e53540. 2013.
Takahara M, Nemoto Y, Oshima S, Matsuzawa Y, Kanai T, Okamoto R, Tsuchiya K, Nakamura T, Yamamoto K,Watanabe M. IL-7 promotes long-term in vitro survival of unique long-lived memory subset generated frommucosal effector memory CD4+ T cells in chronic colitis mice. Immunol Lett. 156(1-2):82-93. 2013 Nov-Dec.
Miyoshi J, Matsuoka K, Inoue N, Hisamatsu T, Ichikawa R, Yajima T, Okamoto S, Naganuma M, Sato T, Kanai T,
Ogata H, Iwao Y, Hibi T. Mucosal healing with oral tacrolimus is associated with favorable medium- andlong-term prognosis in steroid-refractory/dependent ulcerative colitis patients. J Crohns Colitis. 7(12):e609-14.
2013 Dec.
Uo M, Hisamatsu T, Miyoshi J, Kaito D, Yoneno K, Kitazume MT, Mori M, Sugita A, Koganei K, Matsuoka K, Kanai
T, Hibi T. Mucosal CXCR4+ IgG plasma cells contribute to the pathogenesis of human ulcerative colitis throughFcgammaR-mediated CD14 macrophage activation. Gut. 62(12):1734-44. 2013.
Nemoto Y, Kanai T,Takahara M, Oshima S, Nakamura T,Okamoto R,Tsuchiya K,Wanabe M. Bonemarrow-mesenchymal stem cells are a major source of interleukin-7 and sustain colitis by forming the niche forcolitogenic CD4 memory T cells. Gut. 62(8):1142-52. 2013.
Morita Y, Ogihara N, Kanai T, Suzuki H. Technical note: Quantification of neurocranial shape variation using theshortest paths connecting pairs of anatomical landmarks. Am J Phys Anthropol. 151(4):658-66. 2013.
Miyake M, Toguchi H, Nishibayashi T, Higaki K, Sugita A, Koganei K, Kamada N, Kitazume MT, Hisamatsu T, SatoT, Okamoto S, Kanai T, Hibi T. Establishment of novel prediction system of intestinal absorption in humans
using human intestinal tissues. J Pharm Sci. 102(8):2564-71. 2013.
Koike S, .Sujino T, Ohmori H, Shimazaki K, Fukuyama E, Kanai T, Hibi T,Ono T. Gastric emptying rate in subjects
with malocclusion examined by [(13) C] breath test J Oral Rehabil 40(8):574-81. 2013.
Chu PS, Nakamoto N, Ebinuma H, Usui S, Saeki K, Matsumoto A, Mikami Y, Sugiyama K, Tomita K, Kanai T, Saito
H, Hibi T. C-C motif chemokine receptor 9 positive macrophages activate hepatic stellate cells and promote liver
fibrosis in mice. Hepatology. 58(1):337-50. 2013
Hosoe N, Matsuoka K, Naganuma M, Ida Y, Ishibashi Y, Kimura K, Yoneno K, Usui S, Kashiwagi K, Hisamatsu T,Inoue N, Kanai T, Imaeda H, Ogata H, Hibi T. Applicability of second-generation colon capsule endoscope toulcerative colitis: a clinical feasibility study. J Gastroenterol Hepatol 28(7):1174-9. 2013.
Tomita K, Teratani T, Suzuki T, Shimizu M, Sato H, Narimatsu K, Okada Y, Kurihara C, Irie R, Yokoyama H,Shimamura K, Usui S, Ebinuma H, Saito H, Watanabe C, Komoto S, Kawaguchi A, Nagao S, Sugiyama K, Hokari R,Kanai T, Miura S, et al. Free cholesterol accumulation in hepatic stellate cells: Mechanism of liver fibrosis
aggravation in nonalcoholic steatohepatitis in mice. Hepatology. 2013
Matsuoka K, Kanai T. Mechanism and Therapeutic Strategy of Secondary Failure to Anti-Tumor Necrosis Factor-ﾎｱ Monoclonal Antibody Treatment for Crohn's Disease. Digestion. 88(1):17-9. 2013.
Chang J, Hisamatsu T, Shimamura K, Yoneno K, Adachi M, Naruse H, Igarashi T, Higuchi H, Matsuoka K, Kitazume
MT, Ando S, Kamada N, Kanai T, Hibi T. Activated hepatic stellate cells mediate the differentiation ofmacrophages. Hepatol Res. 43(6):658-69. 2013.
Hayashi A, Sato T, Kamada N, Mikami Y, Matsuoka K, Hisamatsu T, Hibi T, Roers A, Yagita H, Ohteki T, Yoshimura
A, Kanai T. A single strain of Clostridium butyricum induces intestinal IL-10-producing macrophages to suppress
acute experimental colitis in mice. Cell Host Microbe. 13(6):711-22. 2013.
Nemoto Y,Kanai T, Takahara M, Oshima S, Okamoto R, Tsuchiya K, Matsumoto S, Watanabe M.
Th1/Th17-mediated interstitial pneumonia in chronic colitis mice independent of intestinal microbiota. Journal ofimmunology. 190(12):6616-25. .2013.
Yoneno K, Hisamatsu T, Shimamura K, Kamada N, Ichikawa R, Kitazume MT, Mori M, Uo M, Namikawa Y,Matsuoka K, Sato T, Koganei K, Sugita A, Kanai T, Hibi T. TGR5 signalling inhibits the production of
pro-inflammatory cytokines by in vitro differentiated inflammatory and intestinal macrophages in Crohn's
disease. Immunology. 139(1):19-29. 2013.
Kanai T, Kamada N, Hisamatsu T. Clinical Strategies for the Blockade of IL-18 in Inflammatory Bowel Diseases.
Curr Drug Targets. 2013.
Mizuno S, Yamagishi Y, Ebinuma H, Nakamoto N, Katahira M, Sasaki A, Sakamoto M, Suzuki H, Kanai T, Hibi T.
Progressive liver failure induced by everolimus for renal cell carcinoma in a 58-year-old male hepatitis B virus
carrier. Clin J Gastroenterol. 6(2):188-192. 2013.
Matsumoto A, Kanai T, Mikami Y, Chu PS, Nakamoto N, Ebinuma H, Saito H, Sato T, Yagita H, Hibi T.

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IL-22-producing RORgammat-dependent innate lymphoid cells play a novel protective role in murine acutehepatitis. PLoS One. 8(4):e62853. 2013.
Nakamura Y, Kanai T, Saeki K, Takabe M, Irie J, Miyoshi J, Mikami Y, Teratani T, Suzuki T, Miyata N, Hisamatsu T,Nakamoto N, Yamagishi Y, Higuchi H, Ebinuma H, Hozawa S, Saito H, Itoh H, Hibi T. CCR2 knockout
exacerbates cerulein-induced chronic pancreatitis with hyperglycemia via decreased GLP-1 receptor expression
and insulin secretion. Am J Physiol Gastrointest Liver Physiol. 304(8):G700-7. 2013.
Takayama T, Kanai T, Matsuoka K, Okamoto S, Sujino T, Mikami Y, Hisamatsu T, Yajima T, Iwao Y, Ogata H, Hibi T.
Long-term prognosis of patients with ulcerative colitis treated with cytapheresis therapy. J Crohns Colitis.
7(2):e49-54. 2013.
Sujino T, Ebinuma H, Hosoe N, Okamoto S, Imaeda H, Hayashi Y, Mukai M, Ogata H, Kanai T, Hibi T. Epstein-barr
virus-associated gastritis: a case report. Dig Dis Sci
58(3):883-6. 2013.
Hisamatsu T, Kanai T, Mikami Y, Yoneno K, Matsuoka K, Hibi T.
Immune aspects of the pathogenesis ofinflammatory bowel disease. Pharmacol Ther. 137(3):283-97. 2013.
Handa T, Kanai T, Sato T, Mikami Y, Sujino T, Hayashi A, Mizuno S, Matsumoto A, Hisamatsu T, Hibi T. Dendritic
cells administered intrarectally penetrate the intestinal barrier to break intestinal tolerance via Th2-medeiatedcolitis in mice .Immunol Lett. 150(1-2):123-9. 2013.
Akagi H, Higuchi H, Sumimoto H, Igarashi T, Kabashima A, Mizuguchi H, Izumiya M, Sakai G, Adachi M,Funakoshi S, Nakamura S, Hamamoto Y, Kanai T, Takaishi H, Kawakami Y, Hibi T. Suppression of myeloid cellleukemia-1 (Mcl-1) enhances chemotherapy-associated apoptosis in gastric cancer cells. Gastric Cancer.
16(1):100-10. 2013.