Bioavailability and Metabolism*PA-01

Poster Room*: Poster Award Applicants

Binding profile of quercetin and its derivatives to human serum albuminmeasured by multiplex drug-site mapping
Hitomi Okuyama1, Mayumi Ikeda2, Yu Ishima2, Miyu Nishikawa3, Shinichi
Ikushiro3, Rie Mukai1

Dept. of Food Sci., Grad. Sch. of Technol., Industrial and Social Sciences, Tokushima
Univ., Japan, 2Dept. of Pharmacokinetics and Biopharmaceutics, Inst. of Biomedical
Sciences, Tokushima Univ., Japan, 3Dept. of Biotechnology, Fac. of Eng., Toyama Pref.
Univ., Japan1*PA-02Comprehensive analyses of quercetin conjugates including glucuronide
sulfate in plasma of quercetin glucosides fed rats
Seiya Tanaka1, Miyu Nishikawa2, Shinichi Ikushiro2, Hiroshi Hara3

Agilent Technologies, Inc., Japan, 2Dept., of Biotech., Fac. of Eng., Toyama Pref. Univ.,
Japan, 3Fac. of Human Life Sci., Fuji Women’s Univ., Japan

1

PA-03
PA-04

Quercetin-embedded extracellular vesicles may be released from HT29 cells
Ryosuke Sugimoto, Akari Ishisaka, Akira Murakami

Dept. of Food Sci. and Nutr., Sch. of Human Sci. and Environ., Univ. of Hyogo., Japan

Effect of inulin on phenolic acid production from flavonol-rich foods infaecal incubations and a randomised acute study in humans
Wenjuan Cong1, Jaroslav Havlik1, Vittoria Marinello1, Min Hou1, Mircea
Martiniuc1, Barbara Nemeckova1, William Mullen2, Tom Preston3, Douglas
Morrison3, Emilie Combet1, Christine Edwards1
1

PA-05

*PA-063

A practical water-soluble composition of Isoquercitrin (from Sophora
Japonica) with improved oral absorption
Naoto Yamaguchi, Hiroaki Kida, Yui Sudaka, Mitsunori Ono
ALPS Pharmaceutical Ind. Co. Ltd., Japan

New insights on the bioavailability of anthocyanins: from structural role tomolecular mechanisms
Hélder Oliveira1, Fuliang Han2, Iva Fernandes1, Victor de Freitas1, Nuno Mateus11
2

34

Human Nutr., Sch. of Med., Univ. of Glasgow, UK, 2ICAMS, Univ. of Glasgow, UK,
SUERC, Univ. of Glasgow, UK

REQUIMTE/LAQV, Chem. and Biochem. Dept., Fac. of Sciences, Univ. of Porto, Portugal,
Coll. of Enology, Northwest A&F Univ., China

PA-07In vivo digested wild strawberries (poly)phenols exert gut-protective
bioactivity
Chris I. R. Gill1, Cheryl Latimer1, Nigel G Ternan1, L Kirsty Pourshahidi1,
Massimiliano Fontana1, Roger Lawther2, Gloria O’Connor2, Lorenzo Conterno3,4,Francesca Fava3, Kieran Touhy3
Nutr. Innovation Centre for Food and Health, Ulster Univ., UK, 2Altnagelvin Area Hosp.,
Western Health and Social Care Trust, UK, 3Dept of Food Quality & Nutr., Fondazione
Edmund Mach, Italy, 4Fermentation and Distillation Group, Laimburg Res. Centre, Italy

1

PA-08

The CHARM study: assessing the cardiovascular health benefits of red
raspberry ellagitannins by stratifying according to urolithin metabotypes
Paul Young Tie Yang1, Wafa Alotaibi1, Rocío García-Villalba2, Francisco A.
Tomás-Barberán2, Ana Rodriguez Mateos1

1

PA-09

PA-11

PA-12

2

Dept. of Nutritional Sciences, SoLCS, Fac. of Life Sci. and Med., King’s Coll. London, UK,
Spanish Natl. Res. Council CEBAS-CSIC, Spain

Administration time significantly affects bioavailability of grape seedproanthocyanidin extract in Fischer 344 rats
Iván Escobar-Martínez, Melina Rojas-Criollo, Álvaro Cruz-Carrión, Francisca I.
Bravo, Anna Arola-Arnal, Manuel Suárez
Universitat Rovira i Virgili, Dept. of Biochem. and Biotechnology, Nutrigenomics Res.
Group, Spain

Comprehensive metabolic study of epigallocatechin gallate in humans:
Characterization of metabolic pathway and identification of the metabolic
enzymeAkane Hayashi, Shimpei Terasaka, Ayame Maihara, Akiyo Kameyama, Yuko
Nukada, Osamu Morita
Safety Sci. Res., Kao Co., Japan

Bioaccessibility and colonic metabolism of phenolic compounds in breads
added with green coffee infusion and enzymatically bioprocessed
Suellen Silva de Almeida1, Nathália Moura-Nunes2, Mariana Monteiro3, Daniel
Perrone1
Chem. Inst., Federal Univ. of Rio de Janeiro, Brazil, 2Nutr. Inst., State Univ. of Rio deJaneiro, Brazil, 3Nutr. Inst., Federal Univ. of Rio de Janeiro, Brazil

1

PA-13

Fermentation of soybean meal improves isoflavones metabolism after
acute intake of soy biscuits by adults
Fabricio de Oliveira Silva1,2, Thayane C.C. Lemos1,3, Diego Sandôra1, Nathália
M.B.Barreto1, Mariana Monteiro3, Daniel Perrone1

Chem. Inst., Federal Univ. of Rio de Janeiro, Brazil, 2Pharm. Fac., Federal Univ. of Rio deJaneiro, Brazil, 3Nutr. Inst., Federal Univ. of Rio de Janeiro, Brazil

135

PA-14

How apple food matrix impacts flavan-3-ols absorption and nutrigenomic
response after a high-fat challenge in minipigs
Laurent-Em.l Monfoulet1, Caroline Buffiere1, Geoffrey Istas2, Claire Dufour3,
Carine le Bourvelec3, Sylvie Mercier1, Dominique Bayle1, Celine Boby4, Didier
Remond1, Patrick Borel5, Ana Rodriguez-Mateos2, Dragan Milenkovic1, Christine
Morand1
Université Clermont Auvergne, INRA, UNH, Unité de Nutr. Humaine, France, 2Dept. of
Nutritional Sciences, King’s Coll., UK, 3INRA Sécurité & Qualité des Produits d’Origine
Végétale - UMR408 Université d’Avignon, France, 4Université Clermont Auvergne, INRA,
VetAgro Sup, UMR Herbivores, France, 5C2VN, INRA, INSERM, Université Aix Marseille,
France1

PA-15

Gallotannins and Lactobacillus plantarum mitigate biomarkers of nonalcoholic fatty liver disease in gnotobiotic mice
Susanne U. Mertens-Talcott1, Chuo Fang1, Zehuan Ding1, Linglin Xie1, Huijuan
Zhou2, Stephen Talcott1, Ke K. Zhang3
Dept. of Nutr. and Food Sci., Coll. of Agric. & Life Sciences., Texas A&M Univ., USA,
Dept. of Statistics., Coll. of Sci., Texas A&M Univ., USA, 3Cent. for Epigenetics & Dis.
Prevention, Inst. of Biosciences & Tech., Coll. of Med., Texas A&M Univ., USA

1
2

PA-16

Whole cell-dependent preparation of 8-prenylnaringenin glucuronides
using UDP-glucuronosyltransferase expressing yeast
Manamu Kitami1, Rie Mukai2, Miyu Nishikawa1, Keisuke Fukaya1, Daisuke
Urabe1, Toshiyuki Sakaki3, Shinichi Ikushiro1

Dept. of Biotech., Fac. of Engineer., Toyama Pref. Univ., Japan, 2Dept. of Food Sci., Grad.
Sch. of Technol., Industrial and Social Sci., Tokushima Univ., Japan, 3Dept. of Pharm., Fac.
of Engineer., Toyama Pref. Univ., Japan

1

PA-17

Metabolism of silymarin in human hepatocytes
Jitka Ulrichová1, Vladimír Křen2, Jiří Vrba1

Dept. of Med. Chem. and Biochem., Palacky Univ., Czech Republic, 2Inst. of Microbiol.,
Czech Acad. of Sci., Czech Republic

1

PA-18

Incomplete hydrolysis of curcumin conjugates by β-glucuronidase
Paula B. Luis1, Andrew G. Kunihiro2, Janet L. Funk3, Claus Schneider1

PA-19

Human urinary excretion of amla (Emblic myrobalan) polyphenols
Ayaka Mori1, Taishi Koyama2, Hideyuki Ito1

1
Dept. of Pharmacology, Vanderbilt Univ. Medical Sch., USA, 2Dept. of Nutritional
Sciences, Univ. of Arizona, USA, 3Dept. of Med., Univ. of Arizona, USA1*PA-202

Dept. of Nutr. Sci., Grad. Sch. of Health and Welfare Sci., Okayama Pref. Univ., Japan,
R&D. Inst., Miki Co., Japan

Protective effect of Mori Cortex Radicis extract against oxidative stress on
PC12 cells and mice brain tissue under hyperglycemia
SoHyeon You1, YunMin Hong1, SukJin Kim1, GaYeong Won1, Su-im Choi1, GunHee Kim2

1
Dept. of Health Fuctional Materials, Grad. Sch. of Duksung Women’s Univ., Korea, 2Dept.
of Food and Nutr. of Duksung Women’s Univ., Korea

36

PA-21

PA-22

Pineapple by-products functional flours –Stability upon to simulated GIT
and human intestinal microbiota–
Débora A. Campos, Ricardo Gómez-García, Ana A. Vilas-Boas, Manuela Pintado
CBQF - Portuguese Catholic Univ., Sch. of Biotechnology, Portugal

PhytoHub, a comprehensive database for metabolites of food
phytochemicals
Frank Giacomoni1, Pierre Micheau1, Jarlei Fiamoncini1,2, Andreia Bento da Silva3,
Yannick Djoumbou Feunang4, David Wishart4, C. Knox5, Claudine Manach1 andall data curators6
Human Nutr. Unit, INRA, Univ. Clermont-Auvergne, France, 2Dept. of Food andExperimental Nutr., Univ of Sao Paulo, Brazil, 3Inst. of Chemical and Biological Technol.,
Univ. NOVA of Lisboa, Portugal, 4Dept. of Biological Sciences, Univ. of Alberta, Canada,
5
OMx Personal Health Analytics, Canada, 6List available on www.phytohub.eu
1

PA-23
A new natural turmeric extract formula increased curcumin (oids)(SY04-5) bioavailability in healthy humans
Pascale Fanca-Berthon1, Mathieu Tenon1, Alexis Manfré1, Corinne Maudet2,
Angelina Dion2, Hélène Chevallier2, Sabrina Lebouter-Banon2
1

Naturex SA, France, 2Biofortis SAS, France*PA-24 Lactobacillus boost bioavailability of polyphenols in onion(SY03-5) Miriam Dormeyer1, Lisa Garbe1, Denis Gyonnet2, Rüdiger Wittlake3, Christin
Koch1

PA-27

1
Symrise AG, Global Innovation Cosmetic Ingredients, Microbiology, Germany, 2Diana
Nova, France, 3Symrise AG, Global Innovation Res. & Technol., Analytical Res. Cent.,
Germany

Comparative study of flavanol bioavailability after consumption of two
soluble cocoa products with different polyphenolic content.
Laura Bravo, Miren Gómez-Juaristi, Sara Martínez-López, Beatriz Sarriá, Raquel
Mateos-BrizInst. of Food Sci., Technol. and Nutri. (ICTAN-CSIC), Natl. Res. Council, Spain

Biomarkers: Analytical Methods, Usability and Omics
PB-01

Temporal variability of isoflavone and lignan concentrations in spot urine
samples in 50 North Carolina adults over a six-week period
Michael Rybak1, Maya Sternberg1, Patrick Simon1, Jon Sobus2, Marsha Morgan2
US Centers for Dis. Control and Prevention, USA, 2US Environmental Protection Agency,
USA

1

PB-02
New simple HPLC-UV/LC-MS analysis of silymarin flavonolignans:(SY04-4) quantification of previously undetectable and/or non-separable
components
Lucie Petrásková, Kristýna Káňová, Kateřina Valentová
Lab. of Biotransformation, Inst. of Microbiology of the CAS, Czechia37

PB-03

Orange juice intake lowers plasma triglycerides in obese patients: acomparative study between traditional lipid measures and lipidomics
Karina Gama dos Santos1,3, Marcos Yukio Yoshinaga2, Adriano de Britto Chaves
Filho2, Aline Alves de Santana1, Franco Maria Lajolo1, Cristiane Kovacs3, Carlos
Daniel Magnoni3, Sayuri Miyamoto2, Neuza Mariko Aymoto Hassimotto1

Food Res. Cent. (FoRC), Sch. of Pharm. Sci., Univ. of Sao Paulo, Brazil, 2Biochem. Dept.,
Inst. of Chem., Univ. of Sao Paulo, Brazil, 3Amb. Nutr., Dante Pazzanese Inst. of Cardiol.,
Brazil

1

PB-04

PB-05

Metabolomic unveiling of a diverse range of Malaysia Hibiscus sabdariffa
L. metabolites dependent on location
Maizatul Hasyima Omar, Adlin Afzan, Mohamad Isa Wasiman

Phytochemistry Unit, Herbal Med. Res. Centre, Natl. Inst. of Health (NIH), Malaysia

A novel multi-targeted quantitative approach for nutrimetabolomics
research
Raúl González-Domínguez1,2, Cristina Andrés-Lacueva1,2

Biomarkers and Nutrimetabolomics Lab., Dept. of Nutr., Food Sciences and Gastronomy,
Food Technol. Reference Net (XaRTA), Nutr. and Food Safety Res. Inst. (INSA), Fac. of
Pharm. and Food Sciences, Univ. of Barcelona, Spain, 2CIBER Fragilidad y Envejecimiento
Saludable (CIBERfes), Instituto de Salud Carlos III, Spain

1

Molecular Targets
PC-01

Exploring target genes involved in the effects of quercetin on response tostress in Caenorhabditis elegans
Begoña Ayuda-Durán, Susana González-Manzano, Sofía Martínez GutiérrezZetina, Eva Sánchez-Hernández, Ana M. González-Paramás, Celestino
Santos-Buelga
Grupo de Investigación en Polifenoles (GIP-USAL), Campus Miguel de Unamuno,
Universidad de Salamanca, Spain*PC-02 Molecular targets of epicatechin: gene expression assessment in(SY06-4) Caenorhabditis elegans
Begoña Ayuda-Durán, Susana González-Manzano, Sofía Martínez GutiérrezZetina, Eva Sánchez-Hernández, Celestino Santos-Buelga, Ana M.
González-Paramás
PC-03

Grupo de Investigación en Polifenoles (GIP-USAL), Campus Miguel de Unamuno,
Universidad de Salamanca, Spain

Chrysin reduces protein level and activity of mature forms of sterol
regulatory element-binding proteins
Kyoko Watanabe1, Masamori Iwase2, Makoto Shimizu2, Tsukasa Suzuki1, Yuji
Yamamoto1, Ryuichiro Sato2, Jun Inoue1

Dept. of Agric. Chem., Fac. of Appl. Biosci., Tokyo Univ. of Agric., Japan, 2Dept. of Appl.
Biol. Chem., Grad. Sch. of Agric. Life Sci., Univ. Tokyo, Japan138

*PC-04

PC-05

PC-06

*PC-07

PC-08

Microbial metabolites of gallotannins attenuate inflammation in RAW 264.7
macrophages through the regulation of the AMPK pathway
Maria J. Castellon Chicas, Chuo Fang, Stephen T. Talcott, Susanne U. MertensTalcott
Dept. of Nutr. and Food Sci., Coll. of Agric. & Life Sci., Texas A&M Univ., USA

Effects and molecular targets of phenolic acids on the stress resistanceand lifespan in Caenorhabditis elegans
Sofía Martínez Gutiérrez-Zetina, Susana González-Manzano, Begoña AyudaDurán, Eva Sánchez-Hernández, Celestino Santos-Buelga, Ana M.
González-Paramás

Grupo de investigación en Polifenoles., Campus Miguel de Unamuno., Salamanca Univ.,Spain

The direct activation of PPARα by 4′-hydroxyl group of resveratrol and afeedforward regulation via cAMP
Rieko Nakata, Yuki Tamori, Mizuki Ito, Shouko Hongo, Hiroyasu Inoue
Dept. of Food Sci. & Nutr., Nara Women’s Univ., Japan

From chemistry to biological implications of polyphenols in Celiac Disease
Ricardo Dias, Catarina Pereira, Rosa Pérez-Gregorio, Nuno Mateus, Victor deFreitas
LAQV/REQUIMTE, Departamento de Química e Bioquímica, Faculdade de Ciências da
Universidade do Porto, Portugal

Sulfotransferase SULT1A expression in the human brain and comparativein silico binding energies of dietary polyphenols to hSULT1A alloenzymes
Arnaud B. Nicot1,2, Elodie Goldwaser3, Céline Labbé3, Jean Harb1,2, Camille
Mathe1,2, Alexandra Garcia1,2, Laureline Berthelot1,2, David A. Laplaud1,2,4, Maria
A. Miteva3
CRTI UMR 1064, Inserm, Nantes Univ., France, 2ITUN, CHU Nantes, France, 3ERL
UMR_S1268 INSERM - UMR8038, Université Paris Descartes, France, 4Dept. of
Neurology, CHU Nantes, France
1

PC-09

miR-222-3p as mediator in the beneficial effects of grape pomace
polyphenols on glycemic control
Asier Léniz1,2,3, María P. Portillo2,3,4, Daniel Martínez-Maqueda5, Jara PérezJiménez5, Alfredo Fernández-Quintela2,3,4

Araba Integrated Health Care Organization. Basque Health Service (Osakidetza), Spain,
Nutr. and Obesity Group, Univ. of the Basque Country (UPV/EHU), Spain, 3Lucio Lascaray
Res. Centre, Spain, 4CIBER Physiopathology of Obesity & Nutr., Inst. Health Carlos III,
Spain, 5Dept. Metab. & Nutr., Inst. Food Sci., Technol., Nutr. (ICTAN-CSIC), Spain12

39

PC-10

Pterostilbene improves triglyceride and phospholipid fatty acid profiles inlivers showing steatosis
Alfredo Fernández-Quintela1,2,3, Leixuri Aguirre1,2,3, Elisabeth Hijona4,5, Luis
Bujanda4,5, María P. Portillo1,2,3

Nutr. and Obesity Group, Univ. of the Basque Country (UPV/EHU), Spain, 2Lucio Lascaray
Res. Centre, Spain, 3CIBER Physiopathology of Obesity and Nutr., Inst. Health Carlos III,
Spain, 4Dept. Gastroenterology (UPV/EHU), Donostia Hosp., Biodonostia Inst., Spain,
5
CIBER Hepatic and Digestive Pathologies (CIBERehd), Inst. of Health Carlos III, Spain
1

PC-11

*PC-12

Effect of chronic cocoa flavanol supplementation on extracellular vesicles
in healthy older adults
Nouf Alroqaiba, Dionne Tannetta, Georgina Dodd, Gessica Serra, Jeremy
Spencer, Parveen Yaqoob
Hugh Sinclair Unit of Human Nutr., Univ. of Reading, UK

A systematic and comprehensive analytical strategy to identify quercetinmodified proteins
Yuki Nakagawa1, Yosuke Iizumi2, Takeshi Ishii3, Hitoshi Ashida4, Mitsugu
Akagawa1

Div. of Appl. Life Sci., Grad. Sch. of Life & Environmental Sci., Osaka Pref. Univ., Japan,
Dept. of Mol.-Targeting Cancer Prevention, Grad. Sch. of Med. Sci., Kyoto Pref. Univ. ofMed., Japan, 3Fac. of Nutr., Kobe Gakuin Univ., Japan, 4Dept. of Agrobiosci., Grad. Sch. ofAgric. Sci., Kobe Univ., Japan1
2*PC-13

Establishment of a novel in vitro TRPV1 ligand evaluation method toassess the effect on sympathetic nerve system
Yuma Unno1, Naomi Osakabei1, Maya Kamao2, Yoshihisa Hirota1

Syst. Eng. & Sci., Grad. Sch. of Eng. & Sci., Shibaura Inst. of Technol., Japan, 2Ext. Ctr.,
Kobe Pharm. Univ., Japan

1

PC-14

PC-15

PC-16

Towards polyphenolic modulators of inflammation and endoplasmic
reticulum stress
Daniela Correia da Silva, Patrícia Valentão, Paula B. Andrade, David M. Pereira

REQUIMTE/LAQV, Laboratório de Farmacognosia, Departamento de Química, Faculdadede Farmácia, Universidade do Porto, Portugal

Effect of in vivo (−)-epicatechin metabolites on eNOS activity in vascularendothelial cells
Tony Y. Momma1, Hagen Schroeter2, Javier I. Ottaviani2
1

Dept. of Nutr., Univ. of California, USA, 2Mars Inc., USA

Identification of the target proteins of quercetin glycoside catabolites ascytoprotective agent
Kouki Morita, Sayaka Nakashima, Toshiyuki Nakamura, Shintaro Munemasa,
Yoshiyuki Murata, Yoshimasa Nakamura
Grad. Sch. of Environmental and Life Sci., Okayama Univ., Japan40

*PC-17 The effect of kaempferol on glucose uptake in L6 myotubes(SY06-6) Hao Jiang1, Yasukiyo Yoshioka2, Yoko Yamashita1, Hitoshi Ashida1

Dept. of Agrobiosci., Grad. Sch. of Agric. Sci., Kobe Univ., Japan, 2Grad. Sch. of Sci.,
Tech. and Innov., Kobe Univ., Japan

1

PC-18

Epicatechin metabolites exert epigenetic regulation in endothelial cells by
modulating DNA methylation profile
Dragan Milenkovic1,2, Ken Declerck3, Yelena Guttman4, Zohar Kerem4, Sylvain
Claude1, Christine Morand1, Wim Vanden Berghe3
INRA, UNH, Université Clermont Auvergne, France, 2Dept. of Internal Med., Div. of
Cardiovascular Med., Sch. of Med., Univ. of California Davis, USA, 3PPES, Dept. of
Biomedical Sciences,Univ. of Antwerp, Belgium, 4Inst. of Biochem., Food Sci. and Nutr.,
The Robert H. Smith Fac. of Agric., Food and Environment, The Hebrew Univ. of
Jerusalem, Israel

1

Target Tissues, Brain-gut-axis and Microflora
PD-01*PD-02

PD-03

Modulation of oxidative stress by dual probiotics/polyphenols systems in
C. elegans
Eva Sánchez-Hernández, Begoña Ayuda-Durán, Sofía Martínez GutiérrezZetina, Susana González-Manzano, Ana M. González-Paramás, Celestino
Santos-Buelga
Grupo de Investigación en Polifenoles (GIP-USAL), Campus Miguel de Unamuno,
Universidad de Salamanca, Spain

Prebiotic mechanistic study of phlorizin, phloretin and chlorogenic acidpolyphenols on Akkermansia muciniphila
Ayano Hojo, Giséle LaPointe
CRIFS, Dept. of Food Sci., Univ. of Guelph, Canada

Differences between apple polyphenols and pectin on the gut microbiota indiet-induced obesity mice
Takayuki Goto, Shiori Aoki, Mina Obara, Toshihiko Shoji
Div. of Food Function Res., Food Res. Inst., NARO, Japan

Disease Prevention: Aging, Metabolic Syndrome, Obesity, Diabetes,
Cardiovascular Disease, Cancer, Muscle Atrophy, Locomotive Syndrome,
Cognitive Disorder, etc
PE-01

Anti-cancer proprieties of natural and synthetic flavonoids which show
inhibitory effects on aurora kinases
Dongsoo Koh1, Miri Yoo1, Yoongho Lim2, Seunghyun Ahn1
1
Dept. of Appl. Chem., Dongduk Women’s Univ., Korea, 2Div. of Bioscience andBiotechnology, BMIC, Konkuk Univ., Korea

41

PE-02

Induction of melanogenesis by 4′-O-methylated flavonoids in B16F10
melanoma cells
Ippei Horibe1,3, Ayako Kumagai1, Hiroshi Takemori2, Yasuo Nagaoka1

Dept. of Life Sci. and Biotechnol., Fac. of Chem., Materials and Bioeng., Kansai Univ.,
Japan, 2United Grad. Sch. of Drug Discovery and Medical Information Sciences, Gifu Univ.,
Japan, 3Nakano Seiyaku Co. Ltd., Japan

1

PE-03

Hydroxytyrosol, a phenolic of virgin olive oil, inhibits cell proliferation andtargets cancer stemness in a 3D cell model of colorectal cancer
Rafaela Pereira1, Sheila Alves1, Sandra Silva1, Inês A. Isidro1,2, , Patrícia GomesAlves1,2, Cristina Albuquerque3, Maria R. Bronze1,2,4, Ana T. Serra1,2
1
iBET, Instituto de Biologia Experimental e Tecnológica, Portugal, 2ITQB NOVA, Portugal,
3

PE-04

4

Unidade de Investigação em Patobiologia Molecular (UIPM), IPOLFG, EPE, Portugal,
iMED, Faculdade de Farmácia da Universidade de Lisboa, Portugal

The effect of olive oil derived compounds in melanoma and melanocyte
cells viability
Cheila Brito1, Ana T. Serra2,3, Sandra Silva2, Maria R. Bronze2,3,4, Marta Pojo1

UIPM, Instituto Português de Oncologia de Lisboa Francisco Gentil E.P.E., Portugal,
IBET- Instituto de Biologia Experimental e Tecnológica, Portugal, 3ITQB NOVA, Portugal,
4iMED, Faculdade de Farmácia da Universidade de Lisboa, Portugal
1
2

PE-05

Evaluation of melanogenesis inhibitor effect of purple plant extracts
Pakinee Bua-on, Kazuhisa Maeda

PE-06

Effects of p-coumaric acid on cell growth and transcriptome profiles in
SNU-16 gastric cancer cells
Mi Gyeong Jang1, Hee Chul Ko2, Jung Min Oh1, Jeong Yong Park1, Se Jae Kim1,2

Dept. of Biosci., Grad. Sch. of Biotech. Sci., Tokyo Univ. of Technol., Japan

Dept. of Biol., Jeju Natl. Univ., Korea, 2Biotechnology Regional Innovation Cent., Jeju Natl.
Univ., Korea
1

PE-07

Clerodendrum trichotomun leaf extract improves potassium oxonateinduced hyperuricemia in mice
Mi Gyeong Jang1, Jung Min Oh1, Jung Young Park1, Songyee Baek2, Hee Chul
Ko2, Sung-Pyo Hur3, Se Jae Kim1, 2

Dept. of Biol., Jeju Natl. Univ., Korea, 2Biotechnology Regional Innovation Cent., Jeju Natl.
Univ., Korea, 3Korea Inst. of Ocean Sci. & Technol., Korea
1

PE-09

ECG and EGCG dimeric procyanidins reduced CRC proliferation andpromoted apoptotic cell death by targeting the lipid rafts-associatedreceptor EGFR
Wei Zhu1,2,3, Ruifeng Wang1, Chunmei Li1, Gerardo G. Mackenzie2, Patricia I.
Oteiza2,3

Coll. of Food Sci. and Technol., Huazhong Agricultural Univ., China, 2Dept. of Nutr., Univ.
of California, USA, 3Dept. of Environmental Toxicology, Univ. of California, USA1

42

PE-10Effect of catechins on activation of JAK/STAT signaling pathway bystaphylococcal enterotoxin A
Yuko Shimamura1, Ami Kurokawa1, Mio Utsumi1, Sohei Ito1, Toshiyuki Kan2,
Shuichi Masuda1

Sch. Food Nutr. Sci., Univ. of Shizuoka, Japan, 2Sch. Pharm. Sci., Univ. of Shizuoka,
Japan

1

*PE-11(−)-Epicatechin mitigates high fat diet-induced hippocampal inflammationand impaired memory in mice
Jiye Kang1,2, Ziwei Wang1,2, Promise Lee1,2, Patricia I. Oteiza1,2
Dept. of Nutr., Univ. of California, USA, 2Dept. of Environmental Toxicology, Univ. of
California, USA

1

PE-12

PE-13

Polyphenols improve redox, vasoactive and permeability markers in
cerebral endothelial cells during diabetes-related hyperglycemia
Janice Taïlé1, Angélique Arcambal1, Anne Gauvin-Bialecki2, Marie-Paule
Gonthier1

1

Université de La Réunion, INSERM, France, 2Université de La Réunion, France

Intake of apple procyanidin improves cognitive function and gut microbiota
in senescence accelerated mice.
Nozomi Tokuzato1, Hiroshi Sakaue1, Masashi Kuroda1, Rie Tsutsumi1, Toshihiko
Shoji3, Saeko Masumoto1,2Dept. of Nutr. and Metab., Grad. Sch. of Nutr. and Bioscience.,Tokushima Univ., Japan,
The Fac. of Food and Agric. Sci., Fukushima Univ., Japan, 3Div. of Food Function Res.,
Food Res. Inst., NARO, Japan

1
2

PE-14

Cerebroprotective effect against cerebral ischemia of the combined extractof black rice and dill in metabolic syndrome rats
Jintanaporn Wattanathorn1,2, Warin Ohnon1

Res. Inst. For HHP&HP, Khon Kaen Univ., Thailand, 2Physiol. Dept, Fac. Med, Khon Kaen
Univ., Thailand
1

PE-15

*PE-16

Tomato decrease oxidative stress in high-fat diet-induced obese anddiabetic mice
Manabu Wakagi, Masao Goto, Naoto Hashimoto, Yuko Takano-Ishikawa
Food Res. Inst., NARO, Japan‘Viking’ aronia berry powder inhibits T cell transfer-induced colitis by
reducing oxidative stressRuisong Pei1, Jiyuan Liu1,2, Derek A. Martin1, Jonathan C. Valdez1, Justin
Jeffery3, Gregory A. Barrett-Wilt4, Zhenhua Liu5, Bradley W. Bolling1

Dept. of Food Sci., Univ. of Wisconsin-Madison, USA, 2Coll. of Food Sci. and Nutr. Engr.,
China Agric. Univ., China, 3Wisconsin Inst. for Med. Res., Univ. of Wisconsin-Madison,
USA, 4Biotech. Cent., Univ. of Wisconsin-Madison, USA, 5Sch. of Public Health and HealthSci., Univ. of Massachusetts, USA1

43

PE-17

Seasonal variation in the phenolic compounds and antioxidant activity of
Sasa quelpaertensis
Hee Chul Ko1, Mi Gyeong Jang2, Jung Min Oh2, Jeong Yong Park2, Mi-Ran Yi1,
Jae-Won Kim1, Songyee Baek1, Se-Jae Kim1,2

Biotechnology Regional Innovation Cent., Jeju Natl. Univ., Korea, 2Dept. of Biol., Jeju Natl.
Univ., Korea

1*PE-18*PE-19*PE-20Modulating lipid and glucose metabolism by glycosylated kaempferol richroasted leaves of Lycium Chinense via upregulating adiponectin and AMPK
activation in obese mice-induced type 2 diabetes
Eunhye Choi, Soon-Mi Shim
Dept. of Food Sci. and Biotechnology, Sejong Univ., Korea

Promotion of lipolysis and browning by Ashitaba chalcones indifferentiated 3T3-L1 cells via AMPK pathway
Risa Hasegawa, Yiyun Liu, Tomoya Kitakaze, Yoko Yamashita, Hitoshi Ashida
Dept. of Agrobiosci., Grad. Sch. of Agric. Sci., Kobe Univ., Japan

Enzymatically modified isoquercitrin promotes lipid and glucose
metabolism through activating AMPKα in C57BL/6 mice
Hao Jiang1, Yasukiyo Yoshioka2, Sihao Yuan1, Yoko Yamashita1, Hitoshi Ashida1
Dept. of Agrobiosci., Grad. Sch. of Agric. Sci., Kobe Univ., Japan, 2Grad. Sch. of Sci.,
Tech. and Innov., Kobe Univ., Japan1*PE-21Chlorogenic and caffeic acids counteract lipid accumulation in THP-1
derived macrophages and reduce monocytes adhesion to endothelial cells
Mirko Marino1, Massimiliano Tucci1, Samuele Venturi1, Marisa Porrini2, Dorothy
Klimis-Zacas2, Patrizia Riso1, Cristian Del Bo’1
Dept. of Food, Environmental and Nutritional Sci. Univ. of Milan, Italy, 2Sch. of Food andAgric. Univ. of Maine, Orono, ME, USA

1

PE-22

PE-23

Time-of-day dependent effect of grape-seed procyanidins on white adipose
tissue in diet-induced obese rats
Marina Colom-Pellicer, Álvaro Cruz-Carrión, Anna Arola-Arnal, Manuel Suárez,Gerard Aragones
Universitat Rovira i Virgili, Dept. of Biochem. and Biotechnology, Nutrigenomics Res.
Group, Spain

Effect of Bifidobacterium fermented milk on anti-obesity
Hitomi Maruta1, Chengduo Wang2, Haruna Tenma1, Yun Ma2, Syoji Nakamura3,
Yusuke Fujii3, Naoki Toyokawa3, Hiromi Yamashita1

Dept. of Nutri. Sci., Okayama Pref. Univ., Japan, 2Dept. of Nutri. Sci., Grad. Sch. of Healthand Welfare Sci., Okayama Pref. Univ., Japan, 3Ohayo Dairy Products Co. Ltd., Japan1*PE-24

Black soybean seed coat extract prevents obesity and its signalingmechanism
Mariko Shiraiwa1, Hitoshi Ashida2, Yoko Yamashita2Fac. of Agric., Kobe Univ., Japan, 2Dept. of Agrobiosci., Grad. Sch. of Agric. Sci., Kobe
Univ., Japan1

44

PE-25(−)-Epicatechin reverses energy metabolism changes associated with theconsumption of a high-fat diet in mice
Ezequiel J. Hid1,2, Ivana Rukavina-Mikusic1,2, Barbara Piotrkowski1,2, Laura
Fischerman1,2, Paula D. Prince1,2, Cesar G. Fraga1,2,3, Laura B. Valdez1,2, Monica
Galleano1,2
Fisicoquímica, Facultad de Farmacia y Bioquímica, Universidad de Buenos Aires,
Argentina, 2CONICET-Universidad de Buenos Aires, IBIMOL, Argentina, 3Dept. of Nutr.,
Univ. of California, USA

1

PE-26

Proinflammatory and antioxidant signaling pathways in kidney of high-fat
fed mice: effect of (−)-epicatechin dietary administration
María C. Litterio1,2, Laura Fischerman1,2, Eleonora Cremonini3, Patricia I. Oteiza3,
Monica Galleano1,2, Cesar G. Fraga1,2,3

Fisicoquímica, Facultad de Farmacia y Bioquímica, Universidad de Buenos Aires,
Argentina, 2CONICET-Universidad de Buenos Aires, IBIMOL, Argentina, 3Dept. of Nutr. andof Environmental Toxicology, Univ. of California, USA1*PE-27

Apple procyanidins facilitate PGC-1α-associated mitochondrial biogenesis
and proteoglycan biosynthesis in chondrocytes
Isao Masuda1, Masato Koike1,2, Kenji Watanabe1,3, Hidetoshi Nojiri2, Koutaro
Yokote1, Takahiko Shimizu1,3

Dept. of Endocrinol. Hematol. and Geriatr., Grad. Sch. of Med., Chiba Univ., Japan, 2Dept.
of Orthop., Grad. Sch. of Med., Juntendo Univ., Japan, 3Dept. of Mech. Aging, Natl. Ctr.
Geriatr. Gerontol., Japan1*PE-28Anthocyanidins promotes beiging of white adipose tissue in mice fed ahigh fat diet via regulation of mitochondrial dynamics
Eleonora Cremonini1, Cecilia M. Rodriguez-Lanzi1,2, Mirko Marino1, Dario E.
Iglesias1, Cesar G. Fraga1,3,4, Patricia I. Oteiza1

Dept. of Nutr. and Environmental Toxicology, Univ. of California USA, 2Instituto de Med y
Biología Experimental de Cuyo (CONICET), - Facultad de Ciencias Médicas, Universidad
Nacional de Cuyo, Argentina, 3Fisicoquímica, Facultad de Farmacia y Bioquímica,
Universidad de Buenos Aires, Argentina, 4Instituto de Bioquímica y Medicina Molecular(IBIMOL), Universidad de Buenos Aires-CONICET, Argentina
1*PE-29PE-30

Flavan 3-ols represent browning ability in white adipose tissue.
Yuiko Ishii, Masaki Kamino, Tomohiro Teshima, Minami Sakou, Yasuyuki Fujii,
Naomi Osakabe
Dept. of Bio-science and Eng., Shibaura Inst. of Technol., Japan

Ameliorative effects of acylated flavonol glycosides on lipid and glucose
metabolisms in HepG2: structural requirements and mode of action
Akifumi Nagatomo1,3, Kiyofumi Ninomiya1,2, Hirosato Kawakami3, Toshio
Morikawa1,2
1
3

Pharm. Res. Technol. Inst., Kindai Univ., Japan, 2Antiaging Cent., Kindai Univ., Japan,
Morishita Jintan Co. Ltd., Japan

45

PE-31

Effects of raw and sun-dried radish roots (Raphanus sativus cv. YR-HyugaRisou) consumption on blood lipid levels in ApoE deficient mice
Hiroki Matsuyama1, Wataru Tanaka1, Yu Suzuki2, Noriyuki Miyoshi2, Yasushi
Matsuura3, Chizuko Yukizaki3, Tatsuo Miyazaki4, Hideyuki Michimoto4, Masanobu
Sakono1, Hiroyuki Sakakibara1

Grad. Sch. of Agric., Univ. of Miyazaki, Japan, 2Grad. Div. of Nutritional and Environmental
Sciences, Univ. of Shizuoka, Japan, 3Miyazaki Pref. Food Res. and Dev. Cent., Japan,
4Michimoto Foods Products Co. Ltd, Japan1*PE-32

PE-33

Effects of daily consumption of monoglucosyl-rutin on diet-induced obese
mice
Wataru Tanaka1, Hiroki Matsuyama1, Daigo Yokoyama1, Yushi Hashizume2,
Mahamadou Tandia2, Masanobu Sakono1, Hiroyuki Sakakibara1
1

Grad. Sch. of Agric., Univ. of Miyazaki., Japan, 2Toyo Sugar Refining Co. Ltd., Japan

Boysenberry polyphenol inhibits capillary rarefaction in brown adipose
tissue and maintains systemic metabolic health in obesity
Ryo Furuuchi1,2, Ippei Shimizu2, Tohru Minamino2
Bourbon Institutes of Health, Bourbon Co., Japan, 2Dept. of Cardiovascular Biol. andMed., Niigata Univ. Grad. Sch. of Medical and Dental Sciences, Japan

1

PE-34

Lipase-catalyzed synthesis of epigallocatechin gallate-based polymer for
long-term release of epigallocatechin gallate with antioxidant property
Sachiko Nitta1, Hiroyuki Iwamoto1,2
Res. Cent. for Green Sci., Fukuyama Univ., Japan, 2Dept. of Biotech., Fukuyama Univ.,
Japan

1

PE-35

*PE-36

Gut microbiota-Tea polyphenols interplay and Celiac Disease
Lucinda J. Bessa, Peter Eaton, Ricardo Dias, Nuno Mateus, Victor de Freitas,
Rosa Pérez-Gregorio

LAQV-REQUIMTE, Dept. of Chem. and Biochem. Univ. of Porto, Portugal

Glucose uptake activity of EGCG analogs in skeletal muscle cells
Ryan Noboru Rutherford1, Shinji Ura2, Noriyuki Natsume3, Aki Yamano4, TakHang Chan5, Kozo Fukumoto2, Andrea Renzetti6, Toshiaki Teruya2

Sci. Education Academy of the Ryukyus, Univ. of the Ryukyus, Japan, 2Fac. of Education,
Univ. of the Ryukyus, Japan, 3Grad. Sch. of Sci., Univ. of the Ryukyus, Japan, 4Okinawa
Res. Cent. Company, Ltd., Japan, 5Dept. of Chem., McGill Univ., Canada, 6Global
Education Inst., Univ. of the Ryukyus, Japan
1

PE-37

A polyphenol-rich strawberry extract have no effect on postprandial
glycemia in a murine model of diet-induced obesity
Paola Galindo-Vidales1, Jesus Espinoza-Alderete1, Lorena Serrano-Corral1, Alma
Felix-Heras1, Veronica Lopez-Teros2, Monica Castro-Acosta1, Marcela de Jesus
Vergara-Jimenez1, Francisco Cabrera-Chavez1
Unidad Académica Ciencias de la Nutricion y Gastronomia, Universidad Autónoma deSinaloa, México, 2Dept. de Ciencias Químico-Biológicas, Universidad de Sonora, Mexico146

PE-39PE-40

Novel phytopharmaceutical derived from leaves of Clerodendrum
colebrookianum Walp. exhibits hepatoprotective and antidiabetic potential
Prashanta Kumar Deb, Biswatrish Sarkar
Dept. of Pharmaceutical Sciences & Technol., Birla Inst. of Technol., India

Antifibrotic effect of methylated quercetin derivatives on TGFβ-induced
hepatic stellate cells
Munkhzul Ganbold1, Yasuhiro Shimamoto2, Farhana Ferdousi3, Kenichi
Tominaga2, Hiroko Isoda1,2,3Sch. of Integrative and Global Majors (SIGMA), Univ. of Tsukuba, Japan, 2Interdisciplinary
Res. Cent. for Catalytic Chem., AIST, Japan, 3Alliance for Res. on the Mediterranean andNorth Africa (ARENA), Univ. of Tsukuba, Japan
1

PE-41

Pterostilbene reduces liver steatosis and the progression to steatohepatitis
in a model of fatty acid induced by a high-fat high-sucrose feeding
Saioa Gómez-Zorita1,2,3, Nerea M. Segues4, Ana Goitia4, Luis Bujanda4,5, María P.
Portillo1,2,3
Nutr. and Obesity Group, Univ. of the Basque Country (UPV/EHU), Spain, 2Lucio Lascaray
Res. Centre, Spain, 3CIBER Physiopathology of Obesity and Nutr. (CIBERobn), Inst. of
Health Carlos III, Spain, 4Dept. Gastroenterology (UPV/EHU), Donostia Hosp., Biodonostia
Inst., Spain, 5CIBER Hepatic and Digestive Pathologies (CIBERehd), Inst. of Health Carlos
III, Spain

1

PE-42

*PE-43The potential of cyanidin 3-O-glucoside in preventing cardiovasculardiseaseThomas Netticadan
Canadian Centre for Agri-Food Res. in Health and Med., Canada

Higher habitual flavonoid intake is associated with lower peripheral arterydisease hospitalizations
Nicola P. Bondonno1,2,3, Kevin Murray4, Catherine P. Bondonno1,2, Joshua R.
Lewis1,2, Kevin D. Croft2, Cecilie Kyrø5, Gunnar Gislason3, Anne Tjønneland5,
Augustin Scalbert6, Aedin Cassidy7, Kim Overvad8, Jonathan M. Hodgson1,2,Frederik Dalgaard3

Sch. of Med. and Health Sciences, Edith Cowan Univ., Australia, 2Sch. of Biomedical
Sciences, The Univ. of Western Australia, Australia, 3Dept. of Cardiology, Herlev &Gentofte Univ. Hosp., Denmark, 4Sch. of Population and Global Health, Univ. of Western
Australia, Australia, 5The Danish Cancer Soc. Res. Centre, Denmark, 6Intl. Agency for Res.
on Cancer, France, 7Norwich Medical Sch., Univ. of East Anglia, UK, 8Dept. of Public
Health, Aarhus Univ., Denmark
147

*PE-44

Flavonoid intake and atrial fibrillation in the Danish Diet Cancer and HealthcohortNicola P. Bondonno1,2,3, Kevin Murray4, Catherine P. Bondonno1,2, Joshua R.
Lewis1,2, Kevin D. Croft2, Cecilie Kyrø5, Gunnar Gislason3, Anne Tjønneland5,
Augustin Scalbert6, Aedin Cassidy7, Jonathan P. Piccini8, Kim Overvad9,10,
Jonathan M. Hodgson1,2, Frederik Dalgaard3

Sch. of Med. and Health Sciences, Edith Cowan Univ., Australia, 2Sch. of Biomedical
Sciences, The Univ. of Western Australia, Australia, 3Dept. of Cardiology, Herlev &Gentofte Univ. Hosp., Denmark, 4Sch. of Population and Global Health, Univ. of Western
Australia, Australia, 5The Danish Cancer Soc. Res. Centre, Denmark, 6Intl. Agency for Res.
on Cancer, France, 7Norwich Medical Sch., Univ. of East Anglia, UK, 8Duke Clinical Res.
Inst., USA, 9Dept. of Public Health, Aarhus Univ., Denmark, 10Dept. of Cardiology, Aalborg
Univ. Hosp., Denmark
1

PE-45

PE-46

Polyphenols protect from the cerebrovascular damage of diabetes-related
hyperglycemia in a stroke mouse model and cerebral endothelial cells
Angélique Arcambal, Janice Taïlé, Marie-Paule Gonthier
Université of de La Réunion, INSERM, France

Blueberry anthocyanin improves postprandial cardiometabolic healthfollowing energy-dense food intake: a RCT in metabolic syndrome
participantsPeter J. Curtis1, Lindsey Berends1, Vera van der Velpen1, Amy Jennings1, Laura
Haag1, Colin D. Kay2, Eric B. Rimm3, Aedin Cassidy4
Norwich Med. Sch. Univ. East Anglia, UK, 2North Carolina State Univ. Plants for Human
Health Inst., USA, 3Dept.’s of Epidemiology & Nutr., Harvard T.H. Chan Sch. of Public
Health, USA, 4Inst. for Global Food Security, Queen’s Univ. Belfast, Northern Ireland

1

PE-47

*PE-48*PE-49Effect of Polyphenols obtained from the Flowers of Syringa vulgaris on the
Stagnant Blood Syndrome
Hisae Oku, Maki Maeda, Fumika Kitagawa, Kyoko Ishiguro
Sch. Pharm. Pharmaceutical Sci, Mukogawa Women’s Univ., Japan

Black soybean seed coat polyphenols improve vascular function bypromoting NO production via GLP-1 secretion
Chiaki Domae1, Fumio Nanba2, Toshinari Maruo2, Toshio Suzuki2, Hitoshi
Ashida1, Yoko Yamashita11Dept. of Agrobiosci., Grad. Sch. of Agric. Sci., Kobe Univ., Japan, 2Fujicco Co., Ltd., Japan

Shikimic acid attenuates skeletal muscle atrophy by activating protein
turnoverJihee Yoo, Changhee Kim, Jae-Kwan Hwang

Dept. of Biotechnology, Yonsei Univ., Korea

48

PE-50

PE-51

PE-52

Cinnamtannin A2 induces skeletal muscle hypertrophy in mice
Masaki Kamino, Kenta Suzuki, Yuiko Ishii, Nayuta Hirashima, Minami Sakou,
Shiori Oyama, Naomi Osakabe
Dept. of Bio-sci. and Eng., Shibaura Inst. of Technol., Japan

Inhibitory effect of 5,7-dimethoxyflavone on muscle atrophy by improving
protein turnover and mitochondrial biogenesis in vitro and in vivo
Changhee Kim, Jae-Kwan Hwang
Dept. of Biotechnology, Yonsei Univ., Korea

Anti-periodontitis effect of macelignan by regulating gingival inflammation
and bone homeostasis
Nahyun Choi1, Changhee Kim2, Jae-Kwan Hwang1,2
Dept. of Biomaterials Sci. and Eng., Yonsei Univ., Korea, 2Dept. of Biotechnology, Yonsei
Univ., Korea

1*PE-53

Theaflavins delay the progression of disuse atrophy induced by hindlimb
suspension in mice
Kenta Suzuki1, Nayuta Hirashima1, Ryo Sukegawa1, Yasuyuki Fujii1, Ayaka
Yamamoto2, Tomoya Ueno2, Naomi Osakabe1
Dept. of Bio-sci. and Eng., Shibaura Inst. of Technol., Japan, 2R&D Div., Yaizu
Suisankagaku Ind. Co., Ltd., Japan
1

PE-54

4-Hydroxyderricin and xanthoangelol from Ashitaba (Angelica keiskei)
prevent dexamethasone-induced muscle atrophy
Hitoshi Ashida1, Yumi Samukawa1, Yasukiyo Yoshioka2, Yusuke Kubota1, Yoko
Yamashita1
Dept. of Agrobiosci., Grad. Sch. of Agric. Sci., Kobe Univ., Japan, 2Grad. Sch. Sci.
Technol. innovation., Kobe Univ., Japan1*PE-55

Ellagic acid in the control of intestinal inflammation/oxidative stressinduced barrier permeabilization
Dario E. Iglesias1,2,3, Cesar G. Fraga1,2,3, Patricia I. Oteiza1,4

Dept. of Nutr., Univ. of California, Davis, USA, 2Physical Chem., Sch. of Pharm. andBiochem., Univ. of Buenos Aires, Argentina, 3IBIMOL, UBA-CONICET, Sch. of Pharm. andBiochem., Univ. of Buenos Aires, Argentina, 4Dept. of Environmental Toxicology, Univ. of
California, USA
1

PE-56

Synthetic ester conjugates of ferulic acid demonstrate anti-inflammatory
and antioxidant activity in human monocytic cells
Nursabah Atli1, Andrew Beekman1, Saurabh Prabhu1, Richard Draijer2, Mark
Searcey1, Colin Kay3, Maria A. O’Connell1
1
3Sch. of Pharm., Univ. of East Anglia, UK, 2Unilever R&D Vlaardingen B.V., Netherlands,
Plants for Human Health Inst., USA49

PE-57

PE-58

Quercetin regulates expression of ACMSD, a key enzyme in tryptophanNAD pathway, and inflammatory mediators in LPS-stimulated microglial
cells
Yukari Egashira, Manami Koshiguchi, Nana Matsumoto, Shizuka Hirai, Takeshi
TakauchiLab. of Food Nutr., Grad. Sch. of Horticulture., Chiba Univ., Japan

Protective effects of hydroxytyrosol-supplemented refined olive oil in
induced arthritisJoão Rocha1, Maria E. Figueira1, Ana T. Serra2,3, Elsa Mecha2, Sandra Silva2,
Ana A. Matias2, Beatriz Martins3, Rita Ventura3, Bruno Vidal4, Rui Pinto1, João E.
C. Fonseca4, Fernando M. Pimentel-Santos5, Maria R. Bronze1,2,3
1*PE-593

iMED- FFUL, Portugal, 2iBET, Instituto de Biologia Experimental e Tecnológica, Portugal,
ITQB NOVA, Portugal, 4iMM – FML, Portugal, 5CEDOC-NOVA Medical Sch., Portugal

Aronia berry extract improves IL-6-induced vascular endothelial
dysfunction
Tomomi Iwashima1, Yoshimi Kishimoto2, Miori Tanaka1, Chie Taguchi2, Kazuo
Kondo2,3, Kaoruko Iida1,4

Dept. of Food and Nutr. Sci., Grad. Sch. of Humanities and Sci., Ochanomizu Univ.,
Japan, 2Endowed Res. Dept. “Food for Health”, Ochanomizu Univ., Japan, 3Inst. of Life
Innovation Studies, Toyo Univ., Japan, 4Inst. for Human Life Innovation, Ochanomizu Univ.,
Japan

1

*PE-60(–)-Epigallocatechin-3-O-gallate stimulates leptin secretion from gastricmucosal cells via 67-kDa laminin receptor/Ca2+ signaling
Chisato Sasaki1, Hiroki Ota1, Takeshi Ishii2, Katsuyuki Mukai3, Akinobu
Matsuyama3, Mitsugu Akagawa1
1

PE-61

*PE-62

2

Div. of Appl. Life Sci., Grad. Sch. of Life and Environ. Sci., Osaka Pref. Univ., Japan,
Dept. of Nutr., Kobe Gakuin Univ., Japan, 3Daicel Corp., Japan

Neolignans from mace on glucose consumption-promoting activity in L6
cells
Toshio Morikawa1,2, Kenchi Miyasaka1, Ikuko Hachiman1, Eriko Nishida1, Osamu
Muraoka1,2, Kiyofumi Ninomiya1,21Pharm. Res. Technol. Inst., Kindai Univ., Japan, 2Antiaging Cent., Kindai Univ., JapanThe ERK signaling cascade in bile-induced Caco-2 monolayer
permeabilization: Prevention by (–)-epicatechin and NADPH oxidase
inhibitors
Ziwei Wang1,2, M. Corina Litterio1,2, David Vauzour3, Patricia I. Oteiza1,21Dept. of Nutr., Univ. of California-Davis, USA, 2Dept. of Environmental Toxicology, Univ. of
California-Davis, USA, 3Norwich Medical Sch., Univ. of East Anglia, UK

50

*PE-63*PE-64*PE-65

PE-66

Co-treatment with kaempferol and luteolin modulates TCDD- and t-BHQinduced drug-metabolizing enzymes
Tomoya Kitakaze, Atsushi Makiyama, Rika Nakai, Yuki Kimura, Hitoshi Ashida
Dept. of Agrobioscience., Grad. Sch. of Agric. Sci., Kobe Univ., Japan

Involvement of circadian rhythm on luteolin-induced Nrf2 activation in the
liver
Tomoya Kitakaze, Atsushi Makiyama, Yoko Yamashita, Hitoshi Ashida
Dept. of Agrobioscience., Grad. Sch. of Agric. Sci., Kobe Univ., Japan

Exploring the colour and bioactivity of anthocyanin derivatives towards
skin healthcare – bridging food and therapeutics
Iva Fernandes, Joana Oliveira, Hélder Oliveira, Patrícia Correia, Paula Araújo,
Ana R. Pereira, Lucinda Bessa, Paula Gameiro, Victor de Freitas, Nuno Mateus

REQUIMTE/LAQV, Dept. of Chem. and Biochem., Fac. of Sci., Portugal

Effectiveness of green tea catechins in the cutaneous ultraviolet radiation(UVR) erythema dose-response: A systematic review and meta-analysis
Mahendra P. Kapoor1, Masaaki Sugita2, Yoshitaka Fukuzawa3, Makoto Ozeki1,
Tsutomu Okubo1
Taiyo Kagaku Co. Ltd., Nutr. Div., Japan, 2Fac. of Sport Sci., Nippon Sport Sci. Univ.,
Japan, 3Dept. of Internal Med., Aichi Medical Univ., Japan

1

PE-67

Polyphenols from persimmon fruits as a functional foods material
Takashi Kometani1,2,3, Keisuke Akaho4, Mari Ohkubo4, Minami Okano4, Kumiko
Takemori1,2Dept. of Food Sci. and Nutr., Fac. of Agric., Kindai Univ., Japan, 2Anti-aging Cent., Kindai
Univ., Japan, 3Agricultural Technol. and Innovation Res. Inst., Kindai Univ., Japan, 4Div. ofAppl. Life Sciences, Grad. Sch. of Agric., Kindai Univ., Japan
1

PE-68

Preventive effect of piceatannol on visceral fat accumulation in
ovariectomized mice
Yoko Fujiwara1,2, Rie Kawawa1, Miharu Shiokoshi1, Tomoko Ishikawa2, Ikuyo
Ichi1,2, Sadao Mori3, Minoru Morita3

Dept. of Nutr. & Food Sci., Grad. Sch. of Hum. & Sci., Ochanomizu Univ., Japan, 2Inst. for
Hum. Life Innov., Ochanomizu Univ., Japan, 3Health Sci. Res. Cent., R&D Inst., Morinaga
and Co., Ltd., Japan
1

PE-69

Effects of quercetin consumption during pregnancy on lipid metabolism of
the offspring in mice
Masakatsu Takashima1, Chihiro Kai1, Wataru Tanaka2, Hiroki Matsuyama2,
Masanobu Sakono1,2, Hiroyuki Sakakibara1,2
1Fac. of Agric., Univ. of Miyazaki, Japan, 2Grad. Sch. of Agric., Univ. of Miyazaki, Japan

51

PE-70Polyphenol intake and metabolic syndrome risk in European adolescents:(SY02-5) the HELENA study
Ratih Wirapuspita Wisnuwardani1,2, Stefaan De Henauw1, Luis A. Moreno3,
Nathalie Michels1 and the HELENA partners
Fac. of Med. and Health Sci., Ghent Univ., Belgium, 2Fac. of Public Health, Mulawarman
Univ., Indonesia, 3Fac. of Health Sci., Univ. of Zaragoza, Spain

1*PE-71 The role of 3,4-dihydroxyphenyl-γ-valerolactone, the gut microbiota(SY06-5) metabolite of epicatechin, in reducing insulin resistance
Jenna Helleur1, Paul W. Needs1, David Vauzour2, Paul A. Kroon1

Food Innovation and Health Programme, Quadram Inst. Bioscience, Norwich Res. Park,UK, 2Univ. of East Anglia, Norwich Res. Park, UK

1*PE-72 Effect of citrus flavanone metabolites on oxidative stress and proteomic(SY05-5) profile in pancreatic β-cells
Sara L. Anacleto1,2, Dragan Milenkovic2,3, John C. Rutledge2, Michelle Salemi4,Paul Kroon4, Paul Needs4, Franco M. Lajolo1, Neuza M. A. Hassimotto1
Univ. of Sao Paulo, Brazil, 2Univ. of California, Davis, USA, 3INRA, France, 4Quadram
Inst., UK1

PE-73
Protective effects of green tea catechin, epigallocatechin gallate and its(SY01-5) metabolites on age-related cognitive dysfunction: mechanism of action
Monira Pervin1, Keiko Unno1, Aimi Nakagawa1, Akira Minami1, Aya Hara2, Akiko
Takagaki2, Fumio Nanjo2, Yoriyuki Nakamura1
1

Univ. of Shizuoka, Japan, 2Mitsui Norin Co. Ltd., Japan*PE-74 Combined feeding of α-glycosyl-isoquercitrin and soluble soybean fiber(SY12-6) prevents glucose intolerance in rats.
Aphichat Trakooncharoenvit1,2, Hiroshi Hara3, Tohru Hira1,2
1
3

Grad. Sch. of Agric., Hokkaido Univ., Japan, 2Res. Fac. of Agric., Hokkaido Univ., Japan,
Dept. of Food Sci. and Human Nutr., Fuji Women’s Univ., Japan

PE-76

Yellow rice wine with high content of flavonoid resists aging in mice
Si Qin, Rong Liu, Yiling Wen, Xi Sun*PE-79

Acute effect of a polyphenol-rich strawberry extract on postprandial
glycemia in a murine model of diet-induced obesity
Jesus G. Espinoza-Alderete1, Paola Galindo-Vidales1, Yubel K. AlarconRodriguez1, Maryant E. Angulo-Leyva1, Marcela de J. Vergara-Jimenez1,
Francisco Cabrera-Chavez1, Veronica Lopez-Teros1, Monica L. Castro-Acosta2

Coll. of Food Sci. and Technol., Hunan Agricultural Univ., China

Facultad de Ciencias de la Nutrición y Gastronomía, Universidad Autónoma de Sinaloa,
México, 2Departamento de Ciencias Químico-Biológicas, Universidad de Sonora, México
152

PE-81

Allophylus africanus phenolics in the discovery of new anticancer drugs
Vera Ribeiro1, Andreia P. Oliveira1, Nelson G.M. Gomes1, David M. Pereira1,
Luísa Araújo2, Paula B. Andrade1, Rui F. Gonçalves1, Patrícia Valentão1

REQUIMTE/LAQV, Laboratório de Farmacognosia, Departamento de Química, Faculdadede Farmácia, Universidade do Porto, Portugal, 2MDS – Medicamentos e Diagnósticos em
Saúde, Avenida dos Combatentes da Liberdade da Pátria, Guinea-Bissau

1

Health Promotion, Intervention and Human Studies*PF-01

Impact of flavanols on the cerebral vasculature: Insights from animal andhuman studies
Catarina Rendeiro1,2,3, Rosie M. Pritchard1, Christian Konopka2, Amanda
Snyder2, Wawrzyniec Dobrucki2, Justin S. Rhodes2,3, Samuel J. E. Lucas1

Sch. of Sport, Exercise and Rehabilitation Sciences, Univ. of Birmingham, UK, 2Beckman
Inst. for Advanced Sci. and Technol., Univ. of Illinois at Urbana-Champaign, USA, 3Cent.
for Nutr., Learning and Memory, Univ. of Illinois at Urbana-Champaign, USA

1

PF-02

Variability in gut microbial metabolism and vascular response to lignans
and isoflavones
Wafa Alotaibi, Paul Young Tie Yang, Wendy Hall, Ana Rodriguez-Mateos

Dept. of Nutritional Sciences, King’s Coll. London, UK, 2Fac. of Life Sciences & Med. Sch.
of Life Courses Sciences, UK

1

PF-03

Association between bedtime and urinary metabolites of estradiol,
melatonin, and isoflavone in young women
Kayoko Shimoi1,2, Akane Yamada1, Hikari Shibata1, Reina Matsuda1, Yuko Saito2,
Michiko Yasuda3
Sch. of Food and Nutritional Sciences, Univ. of Shizuoka, Japan, 2Grad. Sch. of Integlated
Pharmaceutical and Nutritional Sciences, Univ.of Shizuoka, Japan, 3Dept. of Life Studies,
Sugiyama Jogakuen Univ., Japan

1

PF-04

*PF-05An intake of black soybean improved vascular function in human
Yoko Yamashita1, Chiaki Doumae1, Fumio Nanba2, Toshinari Maruo2, Toshio
Suzuki2, Hitoshi Ashida11Dept. of Agrobiosci., Grad. Sch. of Agric. Sci., Kobe Univ., Japan, 2Fujicco Co. Ltd., Japan

Inducing effects on phase ii detoxification enzymes in mice by butterfly pea
extract
Thao Thi Phuong Truong, Parunya Thiyajai, Chaojie Shang, Daichi Kawai,
Tomoyuki Koyama
Dept. of Food Chem Function Nutr., Grad. Sch. of Mar. Sci. Technol., TUMST Univ., Japan53

PF-06

PF-07

Gender differences in the effects of cacao polyphenols on blood pressure,and glucose and lipid metabolism in pre-diabetic subjects
Chisato Oba1, Kazuki Shiina2, Hirofumi Tomiyama2, Chisa Matsumoto2, Syunsuke
Komatsu2, Midori Natsume1, Yukio Ohshiba1, Taketo Yamaji1, Taishiro
Chikamori2, Akira Yamashina2
1

R&D Div., Meiji Co. Ltd., Japan, 2Dept. of Cardiology, Tokyo Medical Univ., Japan

Cognitive effects of chronic cocoa flavanol supplementation in healthyolder adults
Georgina F. Dodd1, Amy Rees1, Gessica Serra1, Claire M. Williams2, Laurie T.
Butler3, Judi A. Ellis2, Daniel J. Lamport2, Anja Hayen4, Jeremy P. E. Spencer1

Dept. of Food & Nutritional Sciences, Univ. of Reading, UK, 2Sch. of Psychology & ClinicalLanguage Sciences, Univ. of Reading, UK, 3Anglia Ruskin Univ., Cambridgeshire, UK,4
P1vital Ltd., UK
1

PF-08

Acute effects of flavanol-rich cocoa on cognitive function in healthy older
adultsCaroline J. Saunders1, Georgina F. Dodd2, Rebecca J. Kean3, Rebecca D.
Hadid4, Claire M. Williams3, Judi A. Ellis3, Daniel J. Lamport3, Laurie T. Butler5,
Jeremy P. E. Spencer2
Suntory Beverage and Food Europe, Lucozade Ribena Suntory Ltd., UK, 2Food &Nutritional Sciences, Univ. of Reading, UK, 3Sch. of Psychology & Clinical Language
Sciences, Univ. of Reading, UK, 4Intl. Brain Res. Organisation, France, 5Anglia Ruskin
Univ., UK1

PF-09

Effects of blackcurrant extract on central arterial stiffness and bloodpressure in older adults
Takanobu Okamoto1, Yuto Hashimoto1, Ryota Kobayashi2, Koichi Nakazato1,
Mark Elisabeth Theodorus Willems3

Dept. of Exercise Physiology, Nippon Sport Sci. Univ., Japan, 2Ctr. for Fundam. Edu.,
Teikyo Univ. of Sci., Japan, 3Inst. of Sport, Univ. of Chichester, UK

1*PF-10PF-11

Moderate to severe ulcerative colitis results in differential metabolism of
cranberry polyphenols by the colon microbiome ex vivo
Maritza Sirven, Susanne U. Mertens-Talcott, Stephen T. Talcott
Dept. of Nutr. and Food Sci., Texas A&M Univ., USA

Inter-individual variability in vascular response to aronia berry(poly)phenols
Melanie Le Sayec1, Geoffrey Istas1, Simone Rampelli2, Emilie Fromentin3, Ana
Rodriguez-Mateos1

Dept. of Nutr.al Sciences, King’s Coll. London, UK, 2Dept. of Pharm. and Biotechnology,
Univ. of Bologna, Italy, 3R&D Dept., Naturex Inc., USA1

54

*PF-12

The antimicrobial activity of industrial sweet orange waste on cariogenic
pathogens
Suvro Saha1,2, Simon Wood2, Christine Bosch1, Thuy Do2, Joanne Maycock1

Sch. of Food Sci. and Nutr., Univ. of Leeds, UK, 2Div. of Oral Biol., Sch. of Dentistry, Univ.
of Leeds, UK

1

PF-13

Acute effects of a polyphenol-rich beverage on cognitive function, mood,
glucose metabolism and cortisol levels in healthy older adults
Marina Gougoulidou1, Georgina F. Dodd1, Anja Hayen2, Daniel J. Lamport3,
Jeremy P.E. Spencer1
Dept. of Food and Nutr. Sci., Univ. of Reading, UK, 2P1vital Ltd, UK, 3Sch. of Psych. &Clin. Lang. Sci., Univ. of Reading, UK

1

PF-15

Phenolics and biological profiling of Xylopia aethiopica leaves: HPLC-DAD
characterization and interference with anti-inflammatory targets
Tiago Macedo1, Vera Ribeiro1, Andreia P. Oliveira1, David M. Pereira1, Fátima
Fernandes Fernandes1, Nelson G. M. Gomes1, Luísa Araújo2, Patrícia Valentão1,
Paula B. Andrade1
REQUIMTE/LAQV, Faculdade de Farmácia, Universidade do Porto, Portugal, 2MDS –Medicamentos e Diagnósticos em Saúde, Avenida dos Combatentes da Liberdade da
Pátria, Guiné-Bissau1*PF-16

Can plant-flavanols protect human vascular function from mental stress?
Rosalind Baynham, Jet Veldhuijzen van Zanten, Catarina Rendeiro

PF-17

Dietary intake of total polyphenol and the risk of all-cause andcardiovascular disease mortality in Japanese adults
Chie Taguchi1, Yoshimi Kishimoto1, Yoichi Fukushima2, Kazuo Kondo1,3, Michiyo
Yamakawa4, Keiko Wada4, Chisato Nagata4

PF-18

Sch. of Sport and Exercise and Rehabilitation Sciences, Univ. of Birmingham, UK

1
Endowed Res. Depart. ‘Food for Health’, Ochanomizu Univ., Japan, 2Nestlé Japan Ltd.,
Japan, 3Inst. Life Innovations Studies, Toyo Univ., Japan, 4Depart. Epidemiology andPreventive Med., Gifu Univ. Grad. Sch. Med., Japan

MaPLE study: reliability and significance of a polyphenol-rich dietary
pattern for the improvement of intestinal permeability in the older subjects
Patrizia Riso1, Stefano Bernardi1, Cristian Del Bo’1, Paul Kroon2, BenjaminKirkup2, Antonio Cherubini3, Nicole Hidalgo Liberona4, Gregorio Peron4, Raul
Gonzalez-Dominguez4, Cristina Andres-Lacueva4, Simone Guglielmetti1

Dept. of Food, Environmental and Nutritional Sci. Univ. of Milan, Italy, 2Quadram Inst.
Bioscience, Norwich Res. Park, UK, 3IRCCS INRCA, Italy, 4CIBERFES, Univ. of Barcelona,
Spain

1

PF-19

Renewed call for industrialization in Africa and its effect on healthpromotions –A case study of Ghana–
Joseph Yeboah, Richmond Lamptey
Univ. Coll. of Agric. and Environmental, Ghana

55

PF-20PF-21

Inhibition of model Maillard reaction products on toxicity of acrylamide invivo
Benyang Wu1, Xiaoyan Chai1, Aiming He2, Yuande Shi2, Chengyan Wu2, Zhenye
Cai2, Jianli Xiao2, Sheng Chen2, Leiwen Xiang2
1

Coll. of Life Sci., Fujian Normal Univ., China, 2Fuqing Branch, Fujian Normal Univ., China

A meta-analysis of blueberry flavonoid effects on cognitive function
Nancy Cheng, Lynne Bell, Daniel Lamport, Claire Williams

Sch. of Psychology and Clinical Language Sciences, Univ. of Reading, UK*PF-22 The effects of chronic cocoa flavanol supplementation on vascular(SY11-5) function in healthy older adults
Amy Rees1, Georgina F. Dodd1, Gessica Serra1, Claire M. Williams2, Laurie T.
Butler3, Judi A. Ellis2, Daniel J. Lamport2, Anja Hayen4, Jeremy P. E. Spencer1

Hugh Sinclair Unit of Human Nutr., Univ. of Reading, UK, 2Dept. of Psychology, Univ. of
Reading, UK, 3Anglia Ruskin Univ., UK, 4P1vital Ltd., UK

1

PF-23

Daily consumption of orange juice modulated intestinal microbiota andimproved glucose and lipids metabolism in women: a controlled clinical
trial
Melaine Priscila Fidélix1, Dragan Milenkovic2,3, Katia Sivieri1, Thais Borges
Cesar1
Dept. of Food and Nutr., Sch. of Pharmaceutical Sci., São Paulo State Univ.-UNESP,
Brazil, 2Dept. of Internal Med., UC Davis Sch. of Med., Univ. of California Davis, USA,
3
Université Clermont Auvergne, INRA, France
1

PF-24

Passiflora setacea juice consumption improves risk factors ofcardiometabolic diseases and modulates gene expression profile ofimmune cells in humans
Isabella de Araújo Esteves Duarte1, Dragan Milenkovic2, Tatiana Karla dos
Santos Borges3, Christine Morand2, Artur Jordão de Magalhães Rosa4,
Calliandra Maria de Souza Silva5, Livia de Lacerda de Oliveira1, Ana Maria
Costa4

Postgraduate Program in Human Nutr., Fac. of Heath Sciences, Univ. of Brasilia, Brazil,
Université Clermont Auvergne, INRA, France, 3Lab. of Cellular Immunology, Fac. of Med.,
Univ. of Brasilia, Brazil, 4Lab. of Food Sci., Embrapa Cerrados, Brazil, 5Postgraduate
Program in Molecular Biol., Biol. Inst., Univ. of Brasilia, Brazil
1
2

PF-28

Effects of yerba mate on cardiovascular health and glucose homeostasis:
randomized controlled clinical trial in healthy and hypercholesterolemic
humansLaura Bravo, Sara Martínez-López, Miren Gómez-Juaristi, Raquel Mateos-Briz,
Beatriz Sarriá
ICTAN-CSIC Natl. Res. Council, Spain56

PF-29Evidence on the wound healing properties of Homalium bhamoense:
Effects upon inflammatory enzymes and interference with NO levels in
RAW 264.7 cells
Rungcharn Suksungworn1,2, Nelson G. M. Gomes3, Andreia P. Oliveira3, Srunya
Vajrodaya1,2, Rui F. Gonçalves3, Patricia Valentão3, Paula B. Andrade3, Sutsawat
Duangsrisai1,2
Dept. of Botany, Fac. of Sci., Kasetsart Univ., Thailand, 2Cent. for Advanced Studies inTropical Natural Resources, Kasetsart Univ., Thailand, 3REQUIMTE/LAQV, Laboratório deFarmacognosia, Faculdade de Farmácia, Universidade do Porto, Portugal

1*PF-31

Preparation and antioxidant activity of polymeric pigments from model
wine solutions
Lingxi Li1, Baoshan Sun1,2
Sch. of Funct. Food and Wine, Shenyang Pharm. Univ., China, 2Instituto Natl. deInvestigação Agrária e Veterinária, Portugal

1*PF-32

Nutrigenomic effects of polyphenol-rich extracts from black bean and blue
corn in a rat model of diabetes mellitus type 2
Karla Damián1, Eugenia Lugo1, Erika Marino1, Inocencio Higuera1, Dragan
Milenkovic2,3Cent. for Res. and Assistance in Technol. and Design of the State of Jalisco, A.C.
(CIATEJ), Mexico, 2Dept. of Internal Med., UC Davis Sch. of Med., Univ. of CA, USA,
3
INRA, Cent. Clermont-Ferrand - Theix, Unité Nutr. Humaine., France
1

PF-33

Increased iron uptake capacity of ultrasonic treated milled rice
Aldrin P. Bonto1, Nichada Jearanaikoon2, Nese Sreenivasulu3, Drexel Camacho1
1*PF-35

3

Chem. Dept., De La Salle Univ., Philippines, 2Synchrotron Light Res. Inst., Thailand,
Grain Quality and Nutri. Cent., Intl. Rice Res. Inst., Philippines

Phenolic profiling of Ficus curtipes Corner leaves and stem bark andassessment of their anti-inflammatory potential
Catarina Andrade1, Federico Ferreres2, Nelson G.M. Gomes1, Sutsawat
Duangsrisai3,4, Nattawut Srisombat3,4, Srunya Vajrodaya3,4, David M. Pereira1,
Angel Gil-Izquierdo2, Paula B. Andrade1, Patricia Valentão1

REQUIMTE/LAQV, Faculdade de Farmácia, Universidade do Porto, Portugal, 2Res. Groupon Quality, Safety and Bioactivity of Plant Foods, CEBAS (CSIC), Spain, 3Dept. of Botany,
Fac. of Sci., Kasetsart Univ., Thailand, 4Cent. for Advanced Studies in Tropical Natural
Resources, Thailand
157

Polyphenols in Foods and Drinks*PG-01

Valorization of onion and fennel wastes as sources of polyphenolicantioxidants toward functional ingredients
Ricardo Gómez Garcia1, Filomena De Biasio2, Domenico Gorgoglione2, Debora
A. Campos1, Cristobal N. Aguilar3, Ana R. Madureira1, Manuela Pintado1
Universidade Católica Portuguesa, CBQF - Centro de Biotecnologia e Química Fina,
Portugal, 2EVRA, Italy, 3Bioprocesses and Bioproducts Group. Food Res. Dept., Sch. ofChem., Autonomous Univ. of Coahuila, Mexico

1

PG-02

PG-03

PG-04

Impact of stir-frying and baking on phenolic profile and antioxidant
activities of blueberry pastry filling
Jie Zheng, Shiyi Ou
Dept. of Food Sci. and Eng., Jinan Univ., China

Antihypertensive properties of low doses of a phenol-enriched grapederived product in hypertensive rats
Raúl López-Fernández, Francisca Isabel Bravo, Maria Begoña Muguerza

Univ. Rovira i Virgili, Biochem. and Biotechnology Dept., Nutrigenomics Res. Group, Spain

Screening of environmental stimuli that produce polyphenol-richstrawberry
Yuichi Uno1, Misaki Ishibashi1, Itsuko Fukuda2, Akitoshi Okino3, Ro Osawa1

Dept. of Bioresource Sci., Grad. Sch. of Agric. Sci., Kobe Univ., Japan, 2Dept. ofAgrobiosci., Grad. Sch. of Agric. Sci., Kobe Univ., Japan, 3FIRST, Inst. of Innovative Res.,Tokyo Tech, Japan1*PG-05

Black soybean seed coat polyphenols prevent AAPH-induced oxidative
DNA damage in hepatic cells
Yasukiyo Yoshioka1, Xiu Li2, Yoko Yamashita2, Hitoshi Ashida2Fac. of Clin. Nutr. Diet., Konan Women’s Univ., Japan, 2Grad. Sch. of Agric. Sci., Kobe
Univ., Japan1*PG-06

Glabridin inhibits dexamethasone-induced muscle atrophy
Yasukiyo Yoshioka1, Yusuke Kubota2, Yumi Samukawa2, Yoko Yamashita2,
Hitoshi Ashida2Fac. of Clin. Nutr. Diet., Konan Women’s Univ., Japan, 2Grad. Sch. of Agric. Sci., Kobe
Univ., Japan

1

PG-07

Investigation of a component involved in color reaction by heating
Tutankhamen’s pea
Miki Hiemori-Kondo1,2, Honoka Uehara1, Yuuki Maekawa2

Dept. of Food Nutr. Sci., Tokushima Bunri Univ., Japan, 2Dept. of Food Sci., Grad. Sch. of
Human Life Sci., Tokushima Bunri Univ., Japan1

58

PG-08

PG-09

Change in elution and absorptivity of catechins from green tea leaves
powdered by fine grinding
Shuichi Masuda, Satoko Hinatsu, Shoko Suzuki, Yuko Shimamura
Sch. Food Nutr. Sci., Univ. of Shizuoka, Japan

The impact of Uva tea extract consumption on psychological stress
Naoko Takamizawa1, Shin-ichiro Yamashita2, Naoko Suzuki2, Kazuo Yamamoto2,
Haruko Takeyama1, Kazunaga Yazawa1, Tsuyoshi Takara3
1

PG-10

PG-11

PG-12

3

Reduced solubility of medicines in tea-based beverages containing
polyphenols
Kazunori Iwanaga, Tomomi Nishida, Daichi Sakaguchi, Mai Otokubo, Tsutomu
Nakamura
Education and Res. Cent. for Clinical Pharm., Osaka Univ. of Pharmaceutical Sciences,Japan

Development of comprehensive analysis method for catechins andtheaflavins using Triple quadrupole LC-MS/MS
Mami Okamoto1, Naoto Furue2, Jun Watanabe1, Naoki Mochizuki2
1

Shimadzu Co., Japan, 2Yokohama Univ. of Pharm., Japan

Tannins with antiglycation activities from water caltrop
Shoichi Suzuki1, Nana Kato1, Satoko Kawabe1, Natsuki Ganeko1, Tomohiro
Uemura2, Hideyuki Ito1
1

PG-13

Res. Org. for Nano & Life Innov., Waseda Univ., Japan, 2ORTHOMEDICO Inc., Japan,
Med. Corp. Seishinkai, Takara Clinic., Japan

2

Dept. of Nutr. Sci., Grad. Sch. of Health and Welfare Sci., Okayama Pref. Univ., Japan,
Hayashikane Sangyo Co., Ltd., Japan

The inhibitory activity of ellagitannins on recombinant human histidine
decarboxylase
Yoko Nitta1, Hideyuki Ito1, Hirohumi Komori2, Hiroshi Ueno3, Hiroe Kikuzaki4

Dept. of Nutr. Sci., Okayama Pref. Univ., Japan, 2Fac. of Educ., Kagawa Univ., Japan,
Lab. of Appl. Microbiol. & Biochem., Ryukoku Univ., Japan, 4Dept. of Food Sci. & Nutr.,
Nara Women's Univ., Japan1
3*PG-14

Proanthocyanidins from peanut skins and their antiglycation properties
Kanano Hosokawa, Hideyuki Ito*PG-15Comparison of B-type procyanidin oligomers on the sympathetic nerve
activation ability by the determination of hemodynamic alterations
Ryo Koizumi, Yuki Sato, Taiki Fushimi, Naomi Osakabe

PG-16

Dept. of Nutr. Sci., Grad. Sch. of Health and Welfare Sci., Okayama Pref. Univ., Japan

Dept. of Bio-Sci. and Eng., Shibaura Inst. of Technol., Japan

The impact of adding milk to coffee on free chlorogenic acid content
Suzanne Pritchard, Nicola Gray, Gunter Kuhnle, Michael Lewis, Jeremy Spencer,
Charlotte Mills
Hugh Sinclair Unit of Human Nutr., Dept. of Food and Nutritional Sci., School Chem., Foodand Pharmacy, Univ. of Reading, UK59

PG-17

Phenolic acids profile and bioactivity of coffee brew prepared from coffee
beans roasted at different levels
Dian Herawati1,2, Puspo Edi Giriwono1,2, Fitriya Nur Annisa Dewi3, Takehiro
Kashiwagi4, Nuri Andarwulan1,2
Southeast Asian Food and Agric. Sci. and Tech. Cent. (Bogor Agric. Univ.), Indonesia,
Dept. of Food Sci. and Tech., IPB Univ. (Bogor Agric. Univ.), Indonesia, 3Primate Res.
Cent., Bogor Agric. Univ., Indonesia, 4Dept of Agric. Chem., Kochi Univ., Japan

1
2

PG-18

PG-20

Modulating effects of polyphenols on the acetaldehyde-induced
cytotoxicity in human keratinocyte HaCaT cells
Takumi Myojin, Wensi Xu, Shintaro Munemasa, Toshiyuki Nakamura, Yoshiyuki
Murata, Yoshimasa Nakamura
Grad. Sch. Environ. Life Sci., Okayama Univ., Japan

Utilization of process water of food production for recovery of polyphenols
Veronika Hellwig1, Johanna Gasser1,2, Ralf Moll1
TH Lübeck /Univ. of Appl. Sciences, Analytical Chem. and Instrumental Analysis,
Germany, 2Universität Bremen/Univ. of Bremen, Inst. of Organic and Analytical Chem.,
Germany1

PG-21

Total polyphenols in the US diet
Joe Vinson

PG-22

Effects of different cooking methods and storage time after cooking
functional ingredients in foodstuffs
Ryo Mannen1, Momoka Kawasaki2, Naoko Otsuki1,2, Kayoko Shimoi1,2, Yoko
Ichikawa1,2

Dept. of Chem., Loyola Sci. Center, Univ. of Scranton, USA

Grad Sch. of Integrated Pharma Nutr. Sci., Univ. of Shizuoka, Japan, 2Sch. of food andNutr. Sci., Univ. of Shizuoka, Japan

1

PG-23

*PG-24

Effect of environmental stress on the betacyanin and antioxidant activity of
Djulis (Chenopodium formosanum Koidz.) sprouts
Ssu-Ping Wang1, Kandi Sridhar2, Pi-Jen Tsai1
1

Quince (Cydonia oblonga Miller) fruit culls: an integral valorization todevelop novel functional ingredients
Ana A. Vilas-Boas1, Catarina Nunes2, Tânia B. Rribeiro1,2, Ana Oliveira1, João
Nunes Nunes2, Manuela Pintado1
1

PG-25

Dept. of Food Sci, Agricultural Coll., NPUST, Taiwan, 2DTAIC, NPUST, Taiwan

2

Universidade Católica Portuguesa, Centro de Biotecnologia e Química Fina, Portugal,
Associação BLC3 - Campus de Tecnologia e Inovação, Oliveira do Hosp., Portugal

Increase of non-extractable proanthocyanidins during processing of
persimmon and quince fruits and the effect on the bile acid-binding activity
Yasunori Hamauzu1, Jutalak Suwannachot1, Runa Gemma2, Nami Nakane2,
Erika Ikeda2

Dept. of Agric., Grad. Sch. of Sci. Technol., Shinshu Univ., Japan, 2Dept. of Agric. Life Sci.,
Fac. of Agric., Shinshu Univ., Japan1

60

PG-26

PG-27

Phenolic composition of Eragrostis tef
Ana López-Pérez, Susana González-Manzano, Begoña Ayuda-Durán, Sofía
Martínez Gutiérrez-Zetina, Ana M. González-Paramás, Celestino Santos-Buelga
Grupo de investigación en Polifenoles, Campus Miguel de Unamuno, Universidad de
Salamanca, Spain

Effects of piceatannol on skin moisture and elasticity
Saori Shimotsuma1, Takayuki Yamamoto1, Yuko Setoguchi1, Sadao Mori1, Minoru
Morita1, Kazuhisa Maeda2
R & D Inst., Morinaga & Co. Ltd., Japan, 2Sch. of Bioscience and Biotechnology, Tokyo
Univ. of Technol., Japan

1

PG-28

Inhibition of alpha-glucosidase and pancreatic lipase by a flavonoid-richaqueous extract of Drymis andina: in vitro and in vivo studies
Bruno Gastaldi1,3, Juana I. Mosele2,3, Silvia B. Gonzalez1, Fresia M. Sofras4,5,Daiana Retta4,5, Cesar G. Fraga2,3, Monica Galleano2,3
Química Orgánica-LIPAM, Univ. Nacional de la Patagonia San Juan Bosco, Argentina,
Fisicoquímica, Facultad de Farmacia y Bioquímica, Univ. de Buenos Aires, Argentina,
3
CONICET-Univ. de Buenos Aires (IBIMOL), Argentina, 4Farmacognosia, Facultad de
Farmacia y Bioquímica, Univ. de Buenos Aires, Argentina, 5CONICET-Universidad de
Buenos Aires (IQUIMEFA), Argentina
1
2

PG-29

PG-30

Factors influencing the bio-functional parameters of Black Carrot (Daucus
carota ssp. Sativus var. atrorubens Alef.)
José Manuel Moreno-Rojas, Cristina Velasco-Tejero, José M. Muñoz-Redondo,
Gema Pereira-Caro, José L. Ordóñez-Díaz

Dept. of Food Sci. and Health. IFAPA-Alameda del Obispo, Spain

Antioxidant activity and phenolic profiles of pigmented chickpea seeds
José Manuel Moreno-Rojas1, José L. Ordóñez-Díaz1, Josefa Rubio2, Víctor OrtízSomovilla1, Gema Pereira-Caro1
Dept. of Food Sci. and Health. IFAPA-Alameda del Obispo, Spain, 2Dept. of Genomic andBiotechnology. IFAPA-Alameda del Obispo, Spain

1

PG-31

PG-32

High performance, transferable and reliable assay of flavanol andprocyanidin in cocoa derived products
Ugo Bussy1, Nicholas Anderson1, Alan Crozier2, Javier Ottaviani1,2, Catherine
Kwik-Uribe1
1

Mars Incorporated, USA, 2Dept. of Nutr., Univ. of California Davis, USA

Antioxidant activity and cell protective effect of Allium Hookeri 95% ethanol
extract
SoHyeon You1, YunMin Hong1, SukJin Kim1, GaYeong Won1, Su-im Choi1, GunHee Kim2
1
Dept. of Health Fuctional Materials, Grad. Sch. of Duksung Women’s Univ., Korea, 2Dept.
of Food and Nutr. of Duksung Women’s Univ., Korea

61

PG-34

Beneficial effects of polyphenols from aronia berries on life-style relateddiseases
Takuya Yamane1,2, Miyuki Kozuka3, Momoko Imai1,4, Satoshi Handa1, Naoki
Harada1, Shigeo Takenaka1, Ryoichi Yamaji1, Tatsuji Sakamoto1, Tetsuo Ishida5,
Hiroshi Inui1, Takenori Nakagaki2, Yoshihisa Nakano1

Ctr. for Res. Dev. Bioresources, Osaka Prefecture Univ., Japan, 2Inst. of Food Sci.,
Nakagaki Consulting Engineer and Co., Ltd., Japan, 3Dept. of Health Nutr., Fac. of Human
Sci., Hokkaido Bunkyo Univ., Japan, 4Dept. of Food Nutr. Mgmt. Studies, Fac. of Human
Dev., Soai Univ., Japan, 5Dept. of Chem., Fac. of Sci., Univ. of the Ryukyus, Japan

1

PG-35

OthersPH-01*PH-02

Effect of storage time of Fresh Garlic (Allium sativum L.) on the nutritional
quality of Black GarlicGema Pereira-Caro, José Luis Ordóñez, Josefa Cañero, José Manuel MuñozRedondo, José Manuel Moreno-Rojas

Dept. Food Sci. and Health, Andalusian Inst. of Agricultural and Fisheries Res. and Training(IFAPA), Spain

Simple synthesis of chalcones derivatives by Wittig reaction
Ndze Denis Jumbam, Wayiza Masamba, Bonani Vinindwa

Dept. of Chem. and Physical Sci., Fac. of Natural Sci., Walter Sisulu Univ., South Africa

Anti-photoaging effects of Agastache rugosa extract and its active
compound tilianin in UVB-treated hairless miceMann-Seok Yun1, Haneul Kang2, Jae-Kwan Hwang1,2

Dept. of Biomaterials Sci. and Eng., Yonsei Univ., Korea, 2Dept. of Biotechnology, Yonsei
Univ., Korea

1

PH-03

PH-04

Chemical synthesis of hydroxytyrosol, oleacein and oleocanthal
Beatriz T. Martins1,2, Sandra Silva1, Elsa Mecha1, Ana Teresa Serra1,2, Maria
Rosário Bronze1,2,3, M. Rita Ventura2

1
IBET, Instituto de Biologia Experimental e Tecnológica, Portugal, 2Instituto de Tecnologia
Química e Biológica António Xavier, ITQB NOVA, Portugal, 3iMED, Faculdade de Farmáciada Universidade de Lisboa, Portugal

Nelumbo nucifera leaves extract decreases inflammatory substance inanimal model of myofascial pain syndrome
Suparporn Muchimapura1,2, Jintanaporn Wattanathorn1,2, Terdthai Tong-un1,2,
Panaporn Wannanon1,2, Wipawee Thukham-mee1,2

Res. Inst. For HHP&HP, Khon Kaen Univ., Thailand, 2Physiol. Dept, Fac. Med, Khon Kaen
Univ., Thailand

162

PH-05

PH-06

The effects of polyphenol content and antioxidant activity in maca
(Lepidium meyenii) phenotypes
Harumi Uto-Kondo1, Tomokazu Yokomaku1, Takuya Hara1, Shouhei
Hatakeyama1, Akifumi Hagiwara2, Koji Kotani1
1Dep. of Biosci. in Daily Life, Nihon Univ., Japan, 2Japan VegeMaca Association, Japan

Development of edible film from yellow skin tuna (T. albacares) gelatinenriched with cinnamon (Cinnamomum zeylanicum) and roselle (Hibiscus
sabdariffa)
Andriati Ningrum1, Martina Widhi Hapsari1, Azka Ainun Nisa1, Heli Siti Halimatul
Munawaroh2
Dept. of Food Sci. and Agricultural Product Technol., Fac. of Agricultural Technol.,
Universitas Gadjah Mada, Indonesia, 2Dept. of Chem., Fac. of Mathematics and Sci.,
Indonesia Univ. of Education, Indonesia

1

PH-07

PH-09

PH-10

Optimization of carotenoid extraction from yellow passion fruit pomaceusing ultrasound-coconut oil
Paramita Dyah Pratiwi, Andriati Ningrum, Supriyadi
Dept. of Food Sci. and Agricultural Product Technol., Fac. of Agricultural Technol.,GadjahMada Univ., Indonesia

Effects of Anchomanes difformis extract on sperm parameters in
streptozotocin-induced diabetic male Wistar rats
Toyin D. Alabi, Nicole Lisa NL Brooks, Oluwafemi O. Oguntibeju

Phytomedicine and Oxidative Stress Res., Fac. of Health and Wellness Sciences, Cape
Peninsula Univ. of Technol., South Africa

Dietary supplementation of selenoneine-containing tuna dark muscle
extract effectively reduces pathology of experimental colorectal cancer inmice
Junko Masuda1, Chiho Umemura1, Miki Yokozawa2, Ken Yamauchi2, Takuya
Seko3, Michiaki Yamashita4 Yumiko Yamashita3

Dept. of Med. Bioeng., Grad. Sch. of Nat. Sci & Technol., Okayama Univ., Japan,
Nutrition Act Co. Ltd., Japan, 3Nat., Res. Inst. of Fish., Sci., Japan, 4Dept. of Food Sci., &Technol., Nat., Fish., Univ., Japan1
2*PH-12 Evaluation of antimicrobial release from biodegradable films, foreseeing(SY13-5) application as food packaging material
Samar Elshamy1, Isao Kobayashi1,3, Kunihiko Uemura1,3, Mitsutoshi Nakajima1,2,3,
Marcos A. Neves1,2,3
Tsukuba Life Sci. Innova. Prog. (T-LSI), Tsukuba Univ., Japan, 2Grad. Sch. of Life &Environ. Sci., Tsukuba Univ., Japan, 3Food Res. Inst., NARO, Japan163

*PH-13 Cinnamtannin A2 reduces anxiety behavior induced by social defeat stress(SY10-5) and improves spatial memory
Yasuyuki Fujii1, Taiki Fushimi1, Jun Sakata1, Shoma Matsunaga1, Shu Taira2,
Naomi Osakabe1
Dept. of Biosci. and Eng., Shibaura Inst. of Technol., Japan, 2The Fac. of Food and Agric.
Sci. Fukushima Univ., Japan1*PH-14

Preparative separation of polyphenols from red wine extracts using highspeed counter current chromatography
Lingxi Li1, Baoshan Sun1,2
Sch. of Funct. Food and Wine, Shenyang Pharm. Univ., China, 2Instituto Natl. deInvestigação Agrária e Veterinária, Portugal

164