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Saito Y, Serizawa H, Kato Y, Nakano M, Nakamura M, Saito H, Suzuki H, Kanai T. First-line eradication for
Helicobacter pylori-positive gastritis by esomeprazole-based triple therapy is influenced by CYP2C19 genotype.
World J Gastroenterol. 21(48):13548-54. 2015.
Mori H, Suzuki H, Matsuzaki J, Tsugawa H, Fukuhara S, Miyoshi S, Hirata K, Seino T, Matsushita M, Masaoka T,Kanai T. Efficacy of 10-day Sitafloxacin-Containing Third-Line Rescue Therapies for Helicobacter pylori Strains
Containing the gyrA Mutation. Helicobacter. 2015.
Uraoka T, Ochiai Y, Fujimoto A, Goto O, Kawahara Y, Kobayashi N, Kanai T, Matsuda S, Kitagawa Y, Yahagi N. A
novel fully synthetic and self-assembled peptide solution for endoscopic submucosal dissection induced ulcer
in the stomach. Gastrointest Endosc. pii: S0016-5107(15)03085-0. 2015.
Umeno J, Hisamatsu T, Esaki M, Hirano A, Kubokura N, Asano K, Kochi S, Yanai S, Fuyuno Y, Shimamura K, Hosoe
N, Ogata H, Watanabe T, Aoyagi K, Ooi H, Watanabe K, Yasukawa S, Hirai F, Matsui T, Iida M, Yao T, Hibi T,Kosaki K, Kanai T, Kitazono T, Matsumoto T. A Hereditary Enteropathy Caused by Mutations in the SLCO2A1Gene, Encoding a Prostaglandin Transporter. PLoS Genet. 11(11):e1005581. 2015.
Nanki K, Mizuno S, Naganuma M, Kanai T. Inflammatory bowel disease and the intestinal microbiota. Nihon
Shokakibyo Gakkai Zasshi. 112(11):1947-55. 2015.
Hisamatsu T, Wada Y, Kanai T. Inflammatory bowel disease and bone decreased bone mineral density. ClinCalcium. 25(11):1639-44. 2015.
Hisamatsu T, Ono N, Imaizumi A, Mori M, Suzuki H, Uo M, Hashimoto M, Naganuma M, Matsuoka K, Mizuno S,Kitazume MT, Yajima T, Ogata H, Iwao Y, Hibi T, Kanai T. Decreased Plasma Histidine Level Predicts Risk ofRelapse in Patients with Ulcerative Colitis in Remission. PLoS One. 10(10):e0140716. 2015.
Nishizawa T, Uraoka T, Sagara S, Suzuki H, Akimoto T, Kanai T, Yahagi N. Endoscopic slip-knot clip suturingmethod: an ex vivo feasibility study (with video). pii: S0016-5107(15)02882-5. 2015.
Horie Y, Ebinuma H, Kanai T. Current status of alcoholic liver diseases in Japan. Nihon Shokakibyo Gakkai Zasshi.
112(9):1630-40. 2015.
Tang C, Kamiya T, Liu Y, Kadoki M, Kakuta S, Oshima K, Hattori M, Takeshita K, Kanai T, Saijo S, Ohno N, Iwakura
Y. Inhibition of Dectin-1 Signaling Ameliorates Colitis by Inducing Lactobacillus-Mediated Regulatory T CellExpansion in the Intestine. Cell Host Microbe. 18(2):183-97. 2015.
Matsuzaki J, Suzuki H, Kobayakawa M, Inadomi JM, Takayama M, Makino K, Iwao Y, Sugino Y, Kanai T.
Association of Visceral Fat Area, Smoking, and Alcohol Consumption with Reflux Esophagitis and Barrett's
Esophagus in Japan.
PLoS One. 10(7): e0133865. 2015.
Kiyohara H, Hisamatsu T, Matsuoka K, Naganuma M, Kameda H, Seta N, Takeuchi T, Kanai T. Crohn's Disease inwhich the Patient Developed Aortitis during Treatment with Adalimumab. Intern Med. 54(14):1725-32. 2015.
Takayama T, Okamoto S, Hisamatsu T, Naganuma M, Matsuoka K, Mizuno S, Bessho R, Hibi T, Kanai T.
Computer-Aided Prediction of Long-Term Prognosis of Patients with Ulcerative Colitis after Cytoapheresis
Therapy. PLoS One. 10(6):e0131197. 2015.
Kashiwagi I, Morita R, Schichita T, Komai K, Saeki K, Matsumoto M, Takeda K, Nomura M, Hayashi A, Kanai T,Yoshimura A. Smad2 and Smad3 Inversely Regulate TGF-β Autoinduction in Clostridium butyricum-ActivatedDendritic Cells. Immunity. 43(1):65-79. 2015.
Soma H, Miyata N, Hozawa S, Higuchi H, Yamagishi Y, Nakamura Y, Saeki K, Kameyama K, Masugi Y, Yahagi N,Kanai T. Ampullary Adenoma Treated by Endoscopic Double-Snare Retracting Papillectomy. Gut Liver.
9(5):689-92.2015.
Sugimoto S, Komatsu H, Morohoshi Y, Kanai T. Recognition of and recent issues in hereditary diffuse gastriccancer. J Gastroenterol. 50(8):831-43. 2015.
Nishizawa T, Uraoka T, Suzuki H, Goto O, Ochiai Y, Fujimoto A, Maehata T, Kanai T, Yahagi N. New endoscopic
suturing method: slip knot clip suturing. Gastrointest Endosc. S0016-5107(15)02323-8. 2015.
Naganuma M, Hosoe N, Kanai T, Ogata H. Recent trends in diagnostic techniques for inflammatory bowel
disease. Korean J Intern Med. 30(3):271-8. 2015.
Chu PS, Ebinuma H, Nakamoto N, Sugiyama K, Usui S, Wakayama Y, Taniki N, Yamaguchi A, Shiba S, Yamagishi Y,Wakita T, Hibi T, Saito H, Kanai T. Genotype-Associated Differential NKG2D Expression on CD56+CD3+
Lymphocytes Predicts Response to Pegylated-Interferon/Ribavirin Therapy in Chronic Hepatitis C. PLoS One.
10(5):e0125664. 2015.
Kanai T, Mikami Y, Hayashi A .A breakthrough in probiotics: Clostridium butyricum regulates gut homeostasis
and anti-inflammatory response in inflammatory bowel disease. Journal of Gastroenterology. 50(9):928-39. 2015.
Sakuraba A, Okamoto S, Matsuoka K, Sato T, Naganuma M, Hisamatsu T, Iwao Y, Ogata H, Kanai T, Hibi T.

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Combination therapy with infliximab and thiopurine compared to infliximab monotherapy in maintaining
remission of postoperative Crohn's disease. Digestion. 91(3):233-8. 2015.
Matano M,Date S, Shimokawa M, Takano A, Fujii M, Ohta Y, Watanabe T, Kanai T, Sato T. Modelling colorectal
cancer using CRISPR-Cas9-mediated engineering of human intestinal organoids. Nature Medicine. 21(3):256-62.
2015.
Nishizawa T, Uraoka T, Ochiai Y, Suzuki H, Goto O, Fujimoto A, Maehata T, Kanai T, Yahagi N. The "two-sword
fencing" technique in endoscopic submucosal dissection. Clin Endosc. 48(1):85-6. 2015.
Naganuma M, Hisamatsu T, Kanai T, Ogata H.
Magnetic resonance enterography of Crohn's disease. Expert
Rev Gastroenterol Hepatol. 9(1):37-45. 2015.
Matsuoka K, Kanai T. The gut microbiota and inflammatory bowel disease. Semin Immunopathol. 37(1):47-55.
2015.
Nishizawa T, Suzuki H, Sagara S, Kanai T, Yahagi N. Dexmedetomidine versus midazolam for gastrointestinalendoscopy: A meta-analysis. Dig Endosc. 27(1):8-15. 2015.
Wada Y, Hisamatsu T* Naganuma M, Matsuoka K, Okamoto S, Inoue N, Yajima T, Kouyama K, Iwao Y, Ogata
H, Hibi T, Abe T, and Kanai T. Risk Factors for Decreased Bone Mineral Density in Japanese Patients withInflammatory Bowel Disease: A Cross-Sectional Study. Clin Nutr. 34(6):1202-9. 2015.