The World Anti-Doping CodeTHE 2010
PROHIBITED LISTINTERNATIONAL
STANDARD

The official text of the Prohibited List shall be maintained by WADA and shall be
published in English and French. In the event of any conflict between the English
and French versions, the English version shall prevail.

This List shall come into effect on 1 January 2010

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THE 2010 PROHIBITED LISTWORLD ANTI-DOPING CODE
Valid 1 January 2010

All Prohibited Substances shall be considered as “SpecifiedSubstances” except Substances in classes S1, S2.1 to S2.5,
S.4.4 and S6.a, and Prohibited Methods M1, M2 and M3.
SUBSTANCES AND METHODS PROHIBITED AT ALL TIMES(IN- AND OUT-OF-COMPETITION)
PROHIBITED SUBSTANCES
S1. ANABOLIC AGENTS
Anabolic agents are prohibited.
1.

Anabolic Androgenic Steroids (AAS)

a. Exogenous* AAS, including:1-androstendiol (5α-androst-1-ene-3β,17β-diol ); 1-androstendione (5αandrost-1-ene-3,17-dione); bolandiol (19-norandrostenediol); bolasterone;boldenone; boldione (androsta-1,4-diene-3,17-dione); calusterone;clostebol; danazol (17α-ethynyl-17β-hydroxyandrost-4-eno[2,3-d]isoxazole);
dehydrochlormethyltestosterone (4-chloro-17β-hydroxy-17α-methylandrosta1,4-dien-3-one); desoxymethyltestosterone (17α-methyl-5α-androst-2-en17β-ol); drostanolone; ethylestrenol (19-nor-17α-pregn-4-en-17-ol);fluoxymesterone; formebolone; furazabol (17β-hydroxy-17α-methyl-5αandrostano[2,3-c]-furazan); gestrinone; 4-hydroxytestosterone (4,17βdihydroxyandrost-4-en-3-one); mestanolone; mesterolone; metenolone;methandienone (17β-hydroxy-17α-methylandrosta-1,4-dien-3-one);methandriol; methasterone (2α, 17α-dimethyl-5α-androstane-3-one-17β-ol);
methyldienolone (17β-hydroxy-17α-methylestra-4,9-dien-3-one); methyl-1testosterone (17β-hydroxy-17α-methyl-5α-androst-1-en-3-one);methylnortestosterone (17β-hydroxy-17α-methylestr-4-en-3-one);methyltestosterone; metribolone (methyltrienolone, 17β-hydroxy-17αmethylestra-4,9,11-trien-3-one); mibolerone; nandrolone; 19norandrostenedione (estr-4-ene-3,17-dione); norboletone; norclostebol;
norethandrolone; oxabolone; oxandrolone; oxymesterone; oxymetholone;
prostanozol (17β-hydroxy-5α-androstano[3,2-c] pyrazole); quinbolone;
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stanozolol; stenbolone; 1-testosterone (17β-hydroxy-5α-androst-1-en-3one); tetrahydrogestrinone (18a-homo-pregna-4,9,11-trien-17β-ol-3-one);
trenbolone and other substances with a similar chemical structure or similar
biological effect(s).
b. Endogenous** AAS when administered exogenously:
androstenediol (androst-5-ene-3β,17β-diol); androstenedione (androst-4-ene3,17-dione); dihydrotestosterone (17β-hydroxy-5α-androstan-3-one) ;prasterone (dehydroepiandrosterone, DHEA); testosterone
and the following metabolites and isomers:
5α-androstane-3α,17α-diol; 5α-androstane-3α,17β-diol; 5α-androstane3β,17α-diol; 5α-androstane-3β,17β-diol; androst-4-ene-3α,17α-diol;
androst-4-ene-3α,17β-diol; androst-4-ene-3β,17α-diol; androst-5-ene3α,17α-diol; androst-5-ene-3α,17β-diol; androst-5-ene-3β,17α-diol;
4-androstenediol (androst-4-ene-3β,17β-diol); 5-androstenedione (androst5-ene-3,17-dione); epi-dihydrotestosterone; epitestosterone; 3α-hydroxy5α-androstan-17-one; 3β-hydroxy-5α-androstan-17-one; 19norandrosterone; 19-noretiocholanolone.

2. Other Anabolic Agents, including but not limited to:
Clenbuterol, selective androgen receptor modulators (SARMs), tibolone,zeranol, zilpaterol.
For purposes of this section:*“exogenous” refers to a substance which is not ordinarily capable of being
produced by the body naturally.
**“endogenous” refers to a substance which is capable of being produced by thebody naturally.

S2. PEPTIDESUBSTANCESHORMONES,GROWTH

FACTORSAND

RELATEDThe following substances and their releasing factors are prohibited:
1. Erythropoiesis-Stimulating Agents [e.g. erythropoietin (EPO),
darbepoetin (dEPO), methoxy polyethylene glycol-epoetin beta(CERA), hematide];
2. Chorionic Gonadotrophin (CG) and Luteinizing Hormone (LH) inmales;
3. Insulins;
4. Corticotrophins;

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5. Growth Hormone (GH), Insulin-like Growth Factor-1 (IGF-1),
Mechano Growth Factors (MGFs), Platelet-Derived Growth Factor(PDGF), Fibroblast Growth Factors (FGFs), Vascular-Endothelial
Growth Factor (VEGF) and Hepatocyte Growth Factor (HGF) as wellas any other growth factor affecting muscle, tendon or ligament protein
synthesis/degradation, vascularisation, energy utilization, regenerative
capacity or fibre type switching;
6. Platelet-derived preparations (e.g. Platelet Rich Plasma, “bloodspinning”) administered by intramuscular route. Other routes ofadministration require a declaration of Use in accordance with theInternational Standard for Therapeutic Use Exemptions.
and other substances with similar chemical structure or similar biologicaleffect(s).

S3. BETA-2 AGONISTSAll beta-2 agonists (including both optical isomers where relevant) are prohibited
except salbutamol (maximum 1600 micrograms over 24 hours) and salmeterol byinhalation which require a declaration of Use in accordance with the International
Standard for Therapeutic Use Exemptions.
The presence of salbutamol in urine in excess of 1000 ng/mL is presumed not tobe an intended therapeutic use of the substance and will be considered as anAdverse Analytical Finding unless the Athlete proves, through a controlled
pharmacokinetic study, that the abnormal result was the consequence of the useof a therapeutic dose (maximum 1600 micrograms over 24 hours) of inhaledsalbutamol.

S4. HORMONE ANTAGONISTS AND MODULATORSThe following classes are prohibited:
1. Aromatase inhibitors including, but not limited to: aminoglutethimide,
anastrozole, androsta-1,4,6-triene-3,17-dione(androstatrienedione), 4-androstene-3,6,17 trione (6-oxo),
exemestane, formestane, letrozole, testolactone.
2. Selective estrogen receptor modulators (SERMs) including, but notlimited to: raloxifene, tamoxifen, toremifene.
3. Other anti-estrogenic substances including, but not limited to:clomiphene, cyclofenil, fulvestrant.

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4. Agents modifying myostatin function(s) including but not limited to:myostatin inhibitors.

S5. DIURETICS AND OTHER MASKING AGENTS
Masking agents are prohibited. They include:
Diuretics, probenecid, plasma expanders (e.g. glycerol; intravenous
administration of albumin, dextran, hydroxyethyl starch and mannitol) andother substances with similar biological effect(s).
Diuretics include:
Acetazolamide, amiloride, bumetanide, canrenone, chlorthalidone,etacrynic acid, furosemide, indapamide, metolazone, spironolactone,thiazides (e.g. bendroflumethiazide, chlorothiazide, hydrochlorothiazide),triamterene, and other substances with a similar chemical structure or similar
biological effect(s) (except drosperinone, pamabrom and topical dorzolamide andbrinzolamide, which are not prohibited).
A Therapeutic Use Exemption for diuretics and masking agents is not valid if anAthlete’s urine contains such substance(s) in association with threshold or subthreshold levels of an exogenous Prohibited Substance(s).

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PROHIBITED METHODS
M1. ENHANCEMENT OF OXYGEN TRANSFER
The following are prohibited:1.

Blood doping, including the use of autologous, homologous or heterologous
blood or red blood cell products of any origin.

2.

Artificially enhancing the uptake, transport or delivery of oxygen, including
but not limited to perfluorochemicals, efaproxiral (RSR13) and modified
haemoglobin
products(e.g.
haemoglobin-based
blood
substitutes,microencapsulated haemoglobin products), excluding supplemental oxygen.

M2. CHEMICAL AND PHYSICAL MANIPULATION
1.

Tampering, or attempting to tamper, in order to alter the integrity andvalidity of Samples collected during Doping Controls is prohibited. These
include but are not limited to catheterisation, urine substitution and/oradulteration (e.g. proteases).

2.

Intravenous infusions are prohibited except for those legitimately received in
the course of hospital admissions or clinical investigations.

M3. GENE DOPING
The following, with the potential to enhance athletic performance, are prohibited:
1-The transfer of cells or genetic elements (e.g. DNA, RNA);

2-The use of pharmacological or biological agents that alter gene expression.

Peroxisome Proliferator Activated Receptor δ (PPARδ) agonists (e.g. GW 1516)
and PPARδ-AMP-activated protein kinase (AMPK) axis agonists (e.g. AICAR) areprohibited.

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6SUBSTANCES AND METHODSPROHIBITED IN-COMPETITION
In addition to the categories S1 to S5 and M1 to M3 defined above,
the following categories are prohibited in competition:

PROHIBITED SUBSTANCES
S6. STIMULANTS
All stimulants (including both optical isomers where relevant) are prohibited,
except imidazole derivatives for topical use and those stimulants included in the2010 Monitoring Program*.
Stimulants include:
a: Non-Specified Stimulants:
Adrafinil; amfepramone; amiphenazole; amphetamine; amphetaminil;
benfluorex; benzphetamine; benzylpiperazine; bromantan; clobenzorex;
cocaine; cropropamide; crotetamide; dimethylamphetamine;
etilamphetamine; famprofazone; fencamine; fenetylline; fenfluramine;
fenproporex; furfenorex; mefenorex; mephentermine; mesocarb;
methamphetamine(d-); p-methylamphetamine;
methylenedioxyamphetamine; methylenedioxymethamphetamine;
methylhexaneamine (dimethylpentylamine); modafinil; norfenfluramine;phendimetrazine; phenmetrazine; phentermine; 4-phenylpiracetam(carphedon); prenylamine; prolintane.
A stimulant not expressly listed in this section is a Specified Substance.
b: Specified Stimulants (examples):Adrenaline**; cathine***; ephedrine****; etamivan; etilefrine; fenbutrazate;
fencamfamin; heptaminol; isometheptene; levmetamphetamine;
meclofenoxate; methylephedrine****; methylphenidate; nikethamide;
norfenefrine; octopamine; oxilofrine; parahydroxyamphetamine;
pemoline; pentetrazol; phenpromethamine; propylhexedrine;
pseudoephedrine*****; selegiline; sibutramine; strychnine;tuaminoheptane and other substances with a similar chemical structure orsimilar biological effect(s).

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*

The following substances included in the 2010 Monitoring Program (bupropion,caffeine, phenylephrine, phenylpropanolamine, pipradol, synephrine) are notconsidered as Prohibited Substances.
**
Adrenaline associated with local anaesthetic agents or by local administration(e.g. nasal, ophthalmologic) is not prohibited.
***
Cathine is prohibited when its concentration in urine is greater than 5micrograms per milliliter.
****
Each of ephedrine and methylephedrine is prohibited when its
concentration in urine is greater than 10 micrograms per milliliter.
*****
Pseudoephedrine is prohibited when its concentration in urine is greaterthan 150 micrograms per milliliter.

S7. NARCOTICS
The following narcotics are prohibited:
Buprenorphine, dextromoramide, diamorphine (heroin), fentanyl and its
derivatives, hydromorphone, methadone, morphine, oxycodone,oxymorphone, pentazocine, pethidine.

S8. CANNABINOIDSNatural or synthetic Δ9-tetrahydrocannabinol (THC) and THC-like cannabinoids(e.g. hashish, marijuana, HU-210) are prohibited.

S9. GLUCOCORTICOSTEROIDS
All glucocorticosteroids are prohibited when administered by oral, intravenous,intramuscular or rectal routes.
In accordance with the International Standard for Therapeutic Use Exemptions, adeclaration of Use must be completed by the Athlete for glucocorticosteroids
administered by intraarticular, periarticular, peritendinous, epidural, intradermal
and inhalation routes, except as noted below.
Topical preparations when used for auricular, buccal, dermatological (includingiontophoresis/phonophoresis), gingival, nasal, ophthalmic and perianal disorders
are not prohibited and require neither a Therapeutic Use Exemption nor adeclaration of Use.

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SUBSTANCES PROHIBITED IN PARTICULARSPORTS
P1. ALCOHOL
Alcohol (ethanol) is prohibited In-Competition only, in the following sports.
Detection will be conducted by analysis of breath and/or blood. The doping
violation threshold (haematological values) is 0.10 g/L.



Aeronautic (FAI)
Archery (FITA)
Automobile (FIA)Karate (WKF)Modern Pentathlon (UIPM) for
disciplines involving shooting
Motorcycling (FIM)
Ninepin and Tenpin Bowling (FIQ)
Powerboating (UIM)

P2. BETA-BLOCKERS
Unless otherwise specified, beta-blockers are prohibited In-Competition only, inthe following sports.











Aeronautic (FAI)
Archery (FITA) (also prohibited
Out-of-Competition)
Automobile (FIA)Billiards and Snooker (WCBS)
Bobsleigh (FIBT)Boules (CMSB)
Bridge (FMB)
Curling (WCF)
Golf (IGF)
Gymnastics (FIG)
Motorcycling (FIM)







Modern Pentathlon (UIPM) for
disciplines involving shooting
Ninepin and Tenpin Bowling (FIQ)
Powerboating (UIM)
Sailing (ISAF) for match racehelms only
Shooting (ISSF, IPC) (alsoprohibited Out-of-Competition)
Skiing/Snowboarding (FIS) in ski
jumping, freestyle aerials/halfpipe
and snowboard halfpipe/big air
Wrestling (FILA)

Beta-blockers include, but are not limited to, the following:
Acebutolol, alprenolol, atenolol, betaxolol, bisoprolol, bunolol, carteolol,
carvedilol, celiprolol, esmolol, labetalol, levobunolol, metipranolol,
metoprolol, nadolol, oxprenolol, pindolol, propranolol, sotalol, timolol.

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