Request for Proposals (RFP)

Immunotherapy in Urothelial Carcinoma
I. BackgroundPfizer Global Medical Grants (GMG), and Merck KGaA, Darmstadt, Germany - Global Medical Education &Academic Organization Relations (Global MedEd & AOR) are collaborating to provide grant support forcontinuing professional education and patient education in the area of Immuno-Oncology. Immuno-Oncology isa priority for Merck KGaA, Darmstadt, Germany and Pfizer Inc, and for the Global Strategic Alliance among ourorganizations.
This publicly posted Request for Proposal (RFP) provides details regarding a general area of interest, sets
timelines for review and approval, and uses an internal company-alliance review process to make final grantdecisions. Organizations are invited to submit an application addressing the knowledge gaps as outlined in theRFP.
For all independent medical education grants, the grant requester (and ultimately the grantee) is responsible forthe design, implementation, and conduct of the independent initiative supported by the grant. Our companies
must not be involved in any aspect of project development, nor the conduct of the independent education
program.
II. Eligibility
Geographic Scope:

Applicant Eligibility
Criteria:••

Primary Geographies of Interest: Europe, Asia, Latin America
Secondary Geography: GlobalNote: Applications for this RFP must have a European or Asian or Latin Americanfocus. However if a program also has a broader global reach it would bewelcomed and encouraged.
The following may apply: professional associations and medical societies,
medical, nursing, allied health, and/or pharmacy professional schools; healthcare
institutions (both large and small); patient advocacy groups, medical educationcompanies; other entities with a mission related to healthcare professional
education and/or healthcare improvement.
If the project involves multiple institutions / organizations / associations all
institutions must have a relevant role and the requesting organization must havea key role in the project.

III. Requirements
Date RFP Issued:

February 15, 2022

Clinical Area:

Oncology – Genitourinary - Urothelial Carcinoma

Specific Area of Interestfor this RFP:

The intent of this RFP is to support independent education initiatives forhealthcare professionals involved in the treatment of patients with locallyadvanced or metastatic urothelial carcinoma (mUC), incl. oncologists, urologists,and specialty nurses. Patient education programs designed to specifically reachpatients with urothelial carcinoma and their caregivers are also in scope for thisRFP.
The goal is to increase understanding of treatment options in the 1st line and 2ndline setting, including 1st line maintenance treatment, for locally-advanced ormetastatic urothelial carcinoma. To include:
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Reviewing the differences between upfront treatment, sequencing
strategies, and delayed (second-line) treatment in mUCRole of chemotherapy in mUC and criteria to define platinum eligibility
Assessing the evidence for maintenance regimens in 1L mUC
Identification of patients who may be eligible for maintenance treatment
Current practices and evidence for therapy options in first and secondline treatment and the factors which influence treatment decisions
Integrating support and patient communication via the whole care teamduring treatment

Grants available to organizations with expertise in urothelial carcinoma
especially professional societies and associations across Europe, Asia and Latin
America.
Proposals for independent medical education programs may include:•••

All activity formats including live in-person, live virtual, enduring virtual,print materials, innovative communication channels, apps, social media,
digital programs, and resources or tools for clinical practice;
Extensions or updates of existing programs, additional languagetranslations of high-quality programs, customized local or regional
implementation guides or algorithms etc.;
Novel decision-making tools for healthcare professions to use with theirpatients to support informed patient decision making and drive patientengagement in their care.

2Expected Approximate
Monetary Range ofGrant Applications:

The total available budget related to this RFP is approximately $775,000 USD.
The typical grant maximum under this RFP will be up to $250,000 USD for
initiatives with large potential reach and impact.
Smaller educational proposals are also encouraged. Organizations that would
like to develop activities for local or regional community healthcare professional
activities or single-country patient programs should also apply. Typically grantamounts for local or regional activities should not exceed around $50,000 USD.
The grant amount the companies will be prepared to fund will depend upon theevaluation of the proposal and costs involved and will be stated clearly in theapproval notification.

Key Dates:

RFP release date: February 15, 2022
Grant application due date: April 12, 2022
Please note the deadline is 23:59 Eastern Standard Time (e.g., New York, GMT 5).
Anticipated Grant Award Notification Date: May 24, 2021
Grants distributed following execution of fully signed Letter of Agreement
Approx. Period of Performance: June 2022 to December 2023 (projects may beshorter; 18-month project maximum)

How to Submit:

Please go to www.cybergrants.com/pfizer/knowledge and sign in. First-timeusers should click “Create your password”.
In the application:• For the question “What type of request are you submitting?” selectResponse to a Request for Proposal (RFP)• For the question “Are you replying to a Request for Proposal as part ofthe Competitive Grant Program?” select Yes• Select the following Competitive Grant Program Name: 2022 Onc G:
Immunotherapy in Urothelial Carcinoma• Select the following Primary Area of Interest: Oncology – Genitourinary
Cancer- Urothelial Carcinoma
Requirements for submission:
Complete all required sections of the online application and upload your project
proposal (see Appendix) in the General RFP Submission field.
If you encounter any technical difficulties with the website, please click the“Technical Questions” link at the bottom of the page.

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IMPORTANT: Be advised applications submitted after the due date will not be
reviewed by the committee.
Questions:If you have questions regarding this RFP, please direct them in writing toJacqueline Waldrop at (Jacqueline.Waldrop@pfizer.com), with the subject line
“RFP Immunotherapy in Urothelial Carcinoma”

Mechanism by which
Applicants will beNotified:

All applicants will be notified via email by the dates noted above.
Applicants may be asked for additional clarification during the review period.

4Appendix - General RFP Submission Requirements

Project Proposals should be single-spaced using Calibri 12-point font and 1-inch margins. Note there is a 15page limit exclusive of references. Please include the following:
Goals and Objectives••

Briefly state the overall goal of the project.
List the objectives you plan to meet with your project, in terms oflearning and expected outcomes.

Needs Assessment for theProject•

Target Audience•Include a description of your organization’s needs assessment for this
proposed project which may include a quantitative baseline datasummary, initial metrics, or a project starting point (please cite data on
gap analyses or relevant patient-level data that informs the statedobjectives) in your target area.
Describe the primary audience(s) targeted for thisproject. Indicate whom you believe will directly benefit from the project
outcomes. Describe the overall population size as well as the size of yoursample population.

Project Design and Methods•

Describe the planned project, the educational approach, and the way theplanned methods address the established need.

Innovation•

Evaluation and Outcomes•

Dissemination Plan•

Anticipated Project Timeline•

Explain what measures you have taken to assure that
this project is original and does not duplicate other projects or materials
already developed. Describe how this project builds upon existing work,
pilot projects, or ongoing projects developed either by your institution orother institutions.
In terms of the metrics used for the needs assessment, describe how
your organization will determine if the gap was addressed for the target
group. Identify the sources of data your organization anticipates using to
make the determination. Describe how your organization is expected tocollect and analyze the data. Explain the method used to control
for other factors outside this project (e.g., use of a control group orcomparison with baseline data). Quantify the amount of change
expected from this project in terms the target audience. Describe how
your organization will determine if the target audience was fully engaged
in the project.
Describe how the project may have extended benefit beyond thegrant. Will the teaching materials be made available to others touse? Will there be tools or resources that are made publicly available
beyond the initial project. Describe how the project outcomes might bebroadly disseminated.
Provide an anticipated timeline for your project including project
start/end dates.

5Additional Information•

Organization Detail•

Budget Narrative••

If there is any additional information you feel the Global Strategic
Alliance should be aware of concerning the importance of this project,please summarize here.
Describe the attributes of the institutions/organizations that will support
and facilitate the execution of the project, the leadership of theproposed project, and the specific role of each institution in theproposed project.
Please include a budget narrative that describes in greater detail the line
items specified in the budget submitted within the application
While estimating your budget please keep the following items in mind:o Independent Medical Education Grants awarded by the Global
Strategic Alliance cannot be used to purchasetherapeutic assets (prescription or non-prescription).
o Overhead rates of more than 28% of the total proposed projectbudget will not be supported.

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