PROGRAM
March 31 (Friday) Kagawa International Conference Hall
Registration (Conference Hall)
Opening ceremonySpecial keynote lecture
Special lecture
Special program “Labeling of Rare Sugars”
Session 1 Food-related properties of rare sugars
Reception Banquet (Rhiga Hotel Zest Takamatsu)
April 1 (Saturday) Kagawa International Conference Hall:
Session 2 Rare sugar production (1) & (2)Session 3 Rare sugars for medical field (1) & (2)Session 4 Physicochemical properties of rare sugars
Session 5 Various usages of rare sugars
April 2 (Sunday)

Exhibition Hall & Kagawa International Conference Hall:

Poster presentation (Exhibition Hall)
Award & closing ceremony

March 31 (Friday)
Kagawa International Conference Hall

09:30~10:30

Registration (Conference Hall)

Opening Ceremony
10:30~10:45
Overall facilitator: Kazuya Akimitsu (Kagawa University, Japan)
10:30~

Congratulation Remarks
Yoshiyuki Kakehi (President of Kagawa University, Japan)
Welcome & Keynote Address
Ken Izumori (President of International Society of Rare Sugars)

Special Keynote Lecture
10:45~11:20
Chair: Yuma Tani (Rare Sugar International Corporation, Japan)
10:45~11:20“Health & Carbohydrates”
Satoru Yamada (Vice President, Director of Endocrinology and Metabolism
Department, and Chief of Diabetes Center of Kitasato University Kitasato
Institute Hospital, Japan)

Special Lecture
11:20~12:20
Chair: Yuma Tani (Rare Sugar International Corporation, Japan)
11:20~12:20

Special lecture: “Nutrition & Health”
Presenter I: Kevin Miller (President of Whole Grain Initiative, USA)
“Processed foods, ingredients, and strategies to promote”
Presenter II: Sebastian Smith (Ingredion Incorporated, USA)
“Sugar Reduction Solutions & Market Trends”

Group photo session
12:20~12:30

Lunch
12:30~13:30

13:30~13:40

Congratulation Remarks
Toyohito Ikeda (Governor of Kagawa Prefecture, Japan)

Special Program“Labeling of Rare Sugars”
13:40~15:00
Chair: Yuma Tani (Rare Sugar International Corporation, Japan)
13:40~15:00 Panel discussion I “Rare sugar labeling in Markets”
Panel discussion II “A proposal for functional sugars in future”
Modulator:
Yuma Tani (Rare Sugar International Corporation, Japan)
Panelists: Food industries’ representatives
Kevin Miller (Whole Grain Initiative, USA)
Chiya Kuraishi (Coca-Cola Tokyo Research & Development Co. Ltd., Japan)
Takanobu Higashiyama (HAYASHIBARA CO., LTD., Japan)
Ed Rogers (Bonumose, Inc., USA)
Sebastian Smith (Ingredion Incorporated, USA)

15:00~15:30 Coffee break

Session 1
Food-related properties of rare sugars
15:30~16:30
Chair: Masahiro Ogawa (Kagawa University, Japan)

15:30~15:44 The influence of fat-carbohydrate content in diet on anti-obesity effects
S01of D-allulose in rats
Masaru Ochiai (Kitasato University, Japan)

15:45~15:59 Physicochemical parameters, volatile compounds and organoleptic properties ofS02

bread prepared with substituted sucrose with rare sugar D-allulose
Saranta Sawettanun (Kagawa University, Japan)

16:00~16:14 Effect of rare sugars on soy sauce brewing and related microorganisms
S03

Miku Miyoshi (Kagawa University / Kagawa Prefectural Industrial TechnologyCenter, Japan)

16:15~16:29 Dietary D-allulose reduces body fat accumulation in rats fed medium-chain
S04

triglyceride diets
Takako Yamada (Matsutani Chemical Industry Co., Ltd., Japan)

Reception Banquet
17:30~20:00
Rhiga Hotel Zest Takamatsu

17:30~18:00 Welcome drink
18:00~20:00 Reception banquet

April 1 (Saturday)
Kagawa International Conference HallSession 2-1
Rare sugar production (1)09:00~10:30
Chair: Ken Izumori (Kagawa University, Japan)

09:00~09:14 Engineering D‑allulose 3‑epimerase from Clostridium cellulolyticum for
S05

improved thermostability using directed evolution facilitated by a nonenzymaticcolorimetric screening assay
Wanmeng Mu (Jiangnan University, China)

09:15~09:29 Enzymatic characterization to produce D-allose from D-allulose by aS06

recombinant L-rhamnose isomerase from Paenibacillus baekrokdamisoli
Chang-Su Park (Daegu Catholic University, Republic of Korea.)

09:30~09:44 Production of eight ketoheptoses using transketolase from Thermus
S07

thermophilus HB8 and D-tagatose 3-epimerase from Pseudomonas cichorii
ST-24
Akihide Yoshihara (Kagawa University, Japan)

09:45~09:59 Effect of organic germanium on isomerization for monosaccharide
S08

Kenji Morimoto (Kagawa University, Japan)

10:00~10:14 Process for producing a high-maltose syrup from rice (Oryza sativa L.) bran
S09

Garry A. Diopol (Industrial Technology Development Institute, Philippines)

10:15~10:29 Improved production process for the low-calorie sugar isomaltulose
S10

Kamaljit Sood (Sainc Energy Limited, UK)

10:30~10:50 Coffee break

Session 2-2
Rare sugar production (2)10:50~12:05
Chair: George W.J. Fleet (Oxford University, UK)10:50~11:04 Development of food-grade expression system for preparing
S11

D-allulose-3-epimerase

Qianzhen Dong (Chinese Academy of Sciences, China)
11:05~11:19 X-ray structure of recombinant ribitol dehydrogenase from Klebsiella oxytoca
S12

Hiromi Yoshida (Kagawa University, Japan)

11:20~11:34 X-ray structure of allose-binding protein coded in allose operon
S13

Shigehiro Kamitori (Kagawa University, Japan)

11:35~11:49 Synthesis of 5-thiosucrose from D-allulose and investigation of protecting
S14

groupsAtsushi Ueda (Nagasaki University, Japan)

11:50~12:04 Synthesis of 3-deoxy-3-fluoro-D-xylulose
S15

Toda Stankovic (University of Vienna, Austria)

Lunch
12:05~13:00

Session 3-1
Rare sugars for medical field (1)13:00~14:30
Chair: Katsuya Yamada (Hirosaki University, Japan)
13:00~13:14 Growth Inhibitory Effects of Rare Sugar D-Allose on Renal Cell Carcinoma
S16

Rikiya Taoka (Kagawa University, Japan)

13:15~13:29 The therapeutic effect of D-allose on colitis-associated carcinogenesis
S17

Xiaodong Li (Kagawa University, Japan)

13:30~13:44 Antitumor effect of D-allose on glioblastoma cell lines
S18

Takahiro Kanda (Kagawa University, Japan)

13:45~13:59 Antiproliferative effects of D-allose associates with the delayed cell cycle
S19transition in pancreatic ductal adenocarcinoma
Asadur Rahman (Kagawa University, Japan)

14:00~14:14 Molecular analysis and physiological significance of D-allulose and D-tagatose
S20

transport by glucose transporters
Kazuyo Kamitori (Kagawa University, Japan)

14:15~14:29 L-Glucose: another path for cancer cells
S21

Katsuya Yamada (Hirosaki University, Japan)

14:30~15:00 Coffee break

Session 3-2
Rare sugars for medical field (2)15:00~16:30
Chair: Koji Murao (Kagawa University, Japan)
15:00~15:14 D-Allulose activates satiety neurons and inhibits appetite neurons: anS22

outstanding ability to regulate feeding and metabolism
Toshihiko Yada (Kansai Electric Power Medical Research Institute / Gifu
University, Japan)

15:15~15:29 D-Allulose activates pro-opiomelanocortin neurons in the hypothalamus andS23

cooperates with glucagon-like peptide-1
Yermek Rakhat (Kansai Electric Power Medical Research Institute / Gifu
University, Japan)

15:30~15:44 D-Allose attenuated RPMCs death induced by high dose of D-glucose via
S24

suppressing ER stress-initiated apoptotic signal pathway
Yuka Yamashita (Kagawa University, Japan)

15:45~15:59 Immunomodulatory effects of D-allose on the function of plasmacytoid dendritic
S25

cells
Katsuaki Hoshino (Kagawa University, Japan)

16:00~16:14 A study on the effect of D-allulose on suppressing postprandial hyperglycemia
S26

in patients with type 2 diabetes
Toshihiro Kobayashi (Kagawa University, Japan)

16:15~16:29 Release of intestinal hormone GLP-1 by D-allulose ameliorates hyperglycemia
S27

through gut - vagal afferent nerves - brain axis
Yusaku Iwasaki (Kyoto Prefectural University, Japan)

16:30~16:45 Coffee break

Session 4
Physicochemical properties of rare sugars
16:45~17:30
Chair: Tomohiko Ishii (Kagawa University, Japan)

16:45~16:59 Hydration behavior of hexoses revisited
S28

Kazuhiro Fukada (Kagawa University, Japan)

17:00~17:14 Thermodynamic study on the effect of monosaccharides on phase transitions ofS29

phospholipid bilayer membrane
Nobutake Tamai (Tokushima University, Japan)

17:15~17:29 Fingerprint of Hydrogen Bonding Network in Rare Sugar Single Crystal
S30

Tomohiko Ishii (Kagawa University, Japan)

Session 5
Various usages of rare sugars
17:30~18:45
Chair: Kazuya Akimitsu (Kagawa University, Japan)

17:30~17:44 Evaluation of rare ketohexoses as antiviral compound
S31

Syed Muniruzzaman (Xavier University of Louisiana, USA)17:45~17:59 Rare Sugars as Insect Control Compounds
S32

Roger A Laine (Louisiana State University, USA)

18:00~18:14 Allitol and D-allulose in native Itea plant of Thailand, the Itea riparia
S33

Verasak Sahachaisaree (Thailand)

18:15~18:29 Characteristic analysis of Itea virginica transketolase 1 (IvTK1)
S34

Susumu Mochizuki (Kagawa University, Japan)

18:30~18:44 Functional analysis of rice phosphoglucose isomerase
S35

Kazuya Akimitsu (Kagawa University, Japan)

April 2 (Sunday)
Exhibition Hall & Kagawa International Conference HallPoster Presentation
09:00~12:00
Exhibition Hall
Poster presenters must stay and give a chance of discussion with audience in the front of eachposter from 9:30 to 10:30 for odd-numbered posters and 10:30 to 11:30 for even-numberedposters.

Lunch
12:00~13:00

Award & Closing Ceremony
13:00~14:00
Kagawa International Conference Hall

13:00~13:30 Award ceremony
Chair: Masaaki Tokuda (Kagawa University, Japan)
Rare Sugar award
Chair: Saisamorn Lumyong (Chiang Mai University, Thailand)
Poster award
13:30~14:00 Closing ceremony
Closing remarks
Ken Izumori (Kagawa University, Japan)
George W.J. Fleet (Oxford University, UK)