JCCG 活動情報 －論文投稿 2019 年―
（主）
：主論文

神経芽腫委員会（主）Iehara T, Yoneda A, Yokota I, Takahashi H, Teramukai S, Kamijyo T, Nakazawa A, Takimoto T,Kikuta A, Yagyu S, Ikeda H, Nakagawara A, Tajiri T. Results of a prospective clinical trial JN-L-10 using
image-defined risk factors to inform surgical decisions for children with low-risk neuroblastoma disease: A
report from the Japan Children's Cancer Group Neuroblastoma Committee. Pediatr Blood Cancer.
66:e27914. 2019. PMID:31342649

腎腫瘍委員会Haruta M, Arai Y, Okita H, Tanaka Y, Takimoto T, Sugino RP, Yamada Y, Kamijo T, Oue T, Fukuzawa M,Koshinaga T, Kaneko Y. Combined Genetic and Chromosomal Characterization of Wilms Tumors
Identifies Chromosome 12 Gain as a Potential New Marker Predicting a Favorable Outcome. Neoplasia.
21:117. 2019. PMID:30530054
Koshinaga T, Takimoto T, Okita H, Tanaka Y, Inoue E, Oue T, Nozaki M, Tsuchiya K, Haruta M, Kaneko
Y, Fukuzawa M. Blastemal predominant type Wilms tumor in Japan: Japan Children's Cancer Group.
Pediatrics international. Pediatr Int. 61:351. 2019. PMID:30786111
大植 孝治, 越永 従道, 福本 弘二. 小児悪性固形腫瘍に対する initial surgical intervention のあり方 腎腫瘍における Initial Surgical Intervention に関する最近の話題. 日本小児血液・がん学会雑誌. 56:113.
2019.

肝腫瘍委員会Hiyama E, Ueda Y, Kurihara S, Kawashima K, Ikeda K, Morihara N, Fukazawa T, Kanawa M. Gene
expression profiling in hepatoblastoma cases of the Japanese Study Group for Pediatric Liver Tumors-2(JPLT-2) trial. European Journal of Molecular Cancer. 1:2. 2019.

横紋筋肉腫委員会
Miyachi M, Tsuchiya K, Hosono A, Ogawa A, Koh K, Kikuta A, Hara J, Teramukai S, Hosoi H. Phase II
study of vincristine, actinomycin-D, cyclophosphamide and irinotecan for patients with newly diagnosed
low-risk subset B rhabdomyosarcoma: A study protocol. Medicine (Baltimore). 98:e18344. 2019.
PMID:31876708

AML 委員会（主）Miyamura T, Moritake H, Nakayama H, Tanaka S, Tomizawa D, Shiba N, Saito AM, Tawa A,Shimada A, Iwamoto S, Hayashi Y, Koike T, Horibe K, Manabe A, Mizutani S, Taga T, Adachi S. Clinicaland biological features of paediatric acute myeloid leukaemia (AML) with primary induction failure in theJapanese Paediatric Leukaemia/Lymphoma Study Group AML-05 study. Br J Haematol. 185:284. 2019.
PMID:30784060
Iacobucci I, Wen J, Meggendorfer M, Choi JK, Shi L, Pounds SB, Carmichael CL, Masih KE, Morris SM,Lindsley RC, Janke LJ, Alexander TB, Song G, Qu C, Li Y, Payne-Turner D, Tomizawa D, Kiyokawa N,Valentine M, Valentine V, Basso G, Locatelli F, Enemark EJ, Kham SKY, Yeoh AEJ, Ma X, Zhou X, Sioson
E, Rusch M, Ries RE, Stieglitz E, Hunger SP, Wei AH, To LB, Lewis ID, D'Andrea RJ, Kile BT, Brown AL,Scott HS, Hahn CN, Marlton P, Pei D, Cheng C, Loh ML, Ebert BL, Meshinchi S, Haferlach T, Mullighan
CG. Genomic subtyping and therapeutic targeting of acute erythroleukemia. Nat Genet. 51:694. 2019.
PMID:30926971
Hyakuna N, Hashii Y, Ishida H, Umeda K, Takahashi Y, Nagasawa M, Yabe H, Nakazawa Y, Koh K, GotoH, Fujisaki H, Matsumoto K, Kakuda H, Yano M, Tawa A, Tomizawa D, Taga T, Adachi S, Kato K.
Retrospective analysis of children with high-risk acute myeloid leukemia who underwent allogeneic
hematopoietic stem cell transplantation following complete remission with initial induction chemotherapy
in the AML-05 clinical trial. Pediatr Blood Cancer. 66:e27875. 2019. PMID:31309713
Shiba N, Yoshida K, Hara Y, Yamato G, Shiraishi Y, Matsuo H, Okuno Y, Chiba K, Tanaka H, Kaburagi T,Takeuchi M, Ohki K, Sanada M, Okubo J, Tomizawa D, Taki T, Shimada A, Sotomatsu M, Horibe K, TagaT, Adachi S, Tawa A, Miyano S, Ogawa S, Hayashi Y. Transcriptome analysis offers a comprehensiveillustration of the genetic background of pediatric acute myeloid leukemia. Blood Adv. 3:3157. 2019.
PMID:31648321
Sakamoto K, Shiba N, Deguchi T, Kiyokawa N, Hashii Y, Moriya-Saito A, Tomizawa D, Taga T, Adachi S,Horibe K, Imamura T. Negative CD19 expression is associated with inferior relapse-free survival in children

with RUNX1-RUNX1T1-positive acute myeloid leukaemia: results from the Japanese PaediatricLeukaemia/Lymphoma Study Group AML-05 study. Br J Haematol. 187:372. 2019. PMID:31247675
Nakashima K, Hasegawa D, Tomizawa D, Miyamura T, Hama A, Iwamoto S, Terui K, Adachi S, Taga T.
Characteristics and outcomes of children with acute myeloid leukemia and Down syndrome who are
ineligible for clinical trials due to severe comorbidities. Pediatr Blood Cancer. 66:e27942. 2019.
PMID:31423753

HLH/LCH 委員会（主）Yanagisawa R, Nakazawa Y, Matsuda K, Yasumi T, Kanegane H, Ohga S, Morimoto A, Hashii Y,Imaizumi M, Okamoto Y, Saito AM, Horibe K, Ishii E; HLH/LCH committee members of the Japan
Children’s Cancer Group. Outcomes in children with hemophagocytic lymphohistiocytosis treated using
HLH-2004 protocol in Japan. Int J Hematol. 109:206. 2019. PMID:30535855
Yanagaisawa R, Matsuda K, Ohga S, Kanegane H, Morimoto A, Okamoto Y, Ohara A, Fukushima K,Sotomatsu M, Nomura K, Saito AM, Horibe K, Ishii E, Nakazawa Y. Factors predicting the recurrence ofEpstein-Barr virus-associated hemophagocytic lymphohistiocytosis in children after treatment using theHLH-2004 protocol. Int J Hematol. 109:612. 2019. PMID:30788725
Sakamoto K, Morimoto A, Shioda Y, Imamura T, Imashuku S, Japan LCH Study Group (JLSG). Central
diabetes insipidus in pediatric patients with Langerhans cell histiocytosis: Results from the JLSG-96/02
studies. Pediatr Blood Cancer. 66:e27454. 2019. PMID:30207064
森本哲. ランゲルハンス細胞組織球症（LCH）. 小児科. 60:1037. 2019.

ALL 委員会
Ishimaru S, Okamoto Y, Imai C, Sakaguchi H, Taki T, Hasegawa D, Cho Y, Kakuda H, Sano H, Manabe A,Imamura T, Kato M, Arakawa Y, Shimonodan H, Sato A, Suenobu S, Inukai T, Watanabe A, Kawano Y,Kikuta A, Horibe K, Ohara A, Koh k. Nationwide survey of pediatric hypodiploid acute lymphoblastic
leukemia in Japan. Pediatr Int. 61:1103. 2019 PMID:31519067
Pui CH, Rebora P, Schrappe M, Attarbaschi A, Baruchel A, Basso G, Cavé H, Elitzur S, Koh K, Liu HC,Paulsson K, Pieters R, Silverman LB, Stary J, Vora A, Yeoh A, Harrison CJ, Valsecchi MG, Ponte di Legno
Childhood ALL Working Group. Outcome of Children With Hypodiploid Acute Lymphoblastic Leukemia:

A Retrospective Multinational Study. J Clin Oncol. 37:770. 2019. PMID:30657737
Kodama Y, Shimada H. Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia. PediatricAcute Lymphoblastic Leukemia. 93. 2019.
Takachi T, Arakawa Y, Nakamura H, Watanabe T, Aoki Y, Ohshima J, Takahashi Y, Hirayama M, MiyamuraT, Sugita K, Koh K, Horibe K, Ishii E, Mizutani S, Tomizawa D. Personalized pharmacokinetic targetingwith busulfan in allogeneic hematopoietic stem cell transplantation in infants with acute lymphoblasticleukemia. Int J Hematol. 110:355. 2019. PMID:31201644

TAM 委員会
Watanabe K. Recent advances in the understanding of transient abnormal myelopoiesis in Down syndrome.
Pediatr Int. 61:222. 2019. PMID:30593694

長期フォローアップ委員会（主）川村眞智子、後藤晶子、前田美穂、足立壮一. 高校生がん患者の教育支援状況に関する調査. 日本
小児科学会雑誌. 123:605. 2019

支持療法委員会
Osone S, Fukushima K, Yano M, Kakazu M, Sano H, Kato Y, Shinkoda Y, Shinoda K, Mori N, Adachi S.
Supportive care for hemostatic complications associated with pediatric leukemia: a national survey in Japan.
Int J Hematol. 110:743. 2019. PMID:31559563