Iode  &  Iodox  information    iode-‐‑‒labo
May  2020

Protecting  healthcare  workers  from  infectious  diseases[For  medical  staﬀ]  Iode-‐‑‒Mask,  Iode-‐‑‒Glove,  Iode-‐‑‒HoodAntibacteria・Antivirus  features  Ordinary mask

To prevent infection by viruses, we developed personal protective equipment (PPE) characterized bystrong antibacterial and antiviral features: Iode-Mask, Iode-Gloves and Iode-Hood. Made of elemental
iodine stably supported on the fabric, our PPE can kill in a short time the bacteria and viruses on itssurface. Even after repeated washing with water, the antibacterial and antiviral effect is preserved for along time (up to about 6 months after continuous or intermittent use, depending on conditions).
Since the mask is made of a soft elastic fabric it is comfortable to wear, and, thanks to the antiviralantibacterial activity, it gives a sense of security. It can also be used above a standard mask or a gauze,
preventing the spread of viruses in the environment.
The product is available with various iodine amounts. Since the antibacterial and antiviral power will
increase proportionally with the amount of iodine loaded on the mask, also the iodine odor will
become slightly stronger. Although the iodine amounts used are not harmful, people with known
allergy to iodine should use the lower one.	  
<Caution> the use of PPE, including our iodine-based products, will not fully protect from acquiring or passing an
infection to another person. Other infection control practices, such as hand-washing, are also important to minimize
your risk of infection.

Injection of watercontaminated with E.ColiBacteria load (CFU/ml)

IodAC  ﬁlter

Immediate and persistent efficacyAvian influenza
virus inactivation

8Time (h)Instant E.Coli eradication

Long lasting disinfection

Virus reduced to1/100.000
in short time

(E.Coli eradication factor from 1/10.000 to 1/1.000.000)[Features]Ø Long-lasting antibacterial and antiviral power* Rapid inactivation of E. coli / Avian influenza
virus (reduced to less than 1/1.000.000)* Continuous / intermittent use for up to 6 months
Ø Iode-Mask fabric filtration performance 3-30µm particle trapping rate : 95~99%( to be worn over a common mask or gauze )Ø Safe on skin and harmlessØ Washable and reusable                  Iode-‐‑‒mask<Mid level antiviral power>（For healthcare and generic users)

Applied above an ordinary
mask or gauze, our product caneradicate viruses on its surface.

Inactivation of avian influenza virus by two types of activated carbon doped²pm 10L·
with iodine (Iod AC-30 and Iod BAC-30, using 1:40 and 1:100 dosage)
Residualtiter
10EID50/0.2ml)
 virus
log(log10EID50/0.2 mL

Performance test of iodine based product:
instant sterilization of water contaminated with bacteria
upon continuous filtration through an activated carbon
filter doped with elementary iodine

Iode-Mask

10  minutes  treatment

76

Iod AC-30

5Iod BAC-30

4Referencebª¾10=5

32101Ç100 Data from Kyoto Sangyo
University (Center for Molecular
Research on Infectious Diseases)bReference 1Ç40

Strong antiviral power
Y 2. Iod AC-30)# Iod BAC-30 !À0>9=2>410=5 b,BQPx

Avian influenza virus inactivation test results on iodine-bearing fabrics®(A / swan / Shimane / 499/83 (H5N3) virus used) y©3>;=.O , )10=5{¶
100 L!ÆDA
SampleVirus solution(400µL） c

Cloth [U.BQPx+Mq
Mask Ny
washed 1h after iodine loading≤ 0.5 *
Iod AC-30"À0>9=2>410=5b²pm
Cloth Mask
Ny+PU’’≤ 0.5 )+ Iod AC-30 .
10 minutes
10=5Clothing
fabric Wo o¨,¿’’ BQPx.¬-≤ 0.5
treatment
40 G¶b!BQPx"IodBAC-30 )+ Iod
FabricmatPU )# 100 G¶!10=5’’≤ 0.5
Reference
6.67
AC-30 !ru* BQPxwg, *-,* Residual virus titer （log10EID50/0.2mL）
Ny: Nylon, PU: Polyurethane, Wo: Wool

Iode-‐‑‒hoodIode-‐‑‒glove<Mid level antiviral power>（For generic users)<Low level><High level>
4<High level antiviral power>（For healthcare users)<High level antiviral power>（For healthcare users)

For healthcare users

Iode  &  Iodox  information    iode-‐‑‒labo

May  2020

Assuring  high  antiviral  power  with  just  a  spray[For  healthcare  and  generic  users]  Iodox-‐‑‒spray
Antibacterial/antiviral,  antifungal,  deodorant  Just lightly spray on the surface of conventional masks, towels, clothes,doorknobs, hands, etc. to assure a long-lasting antibacterial and antiviral effectand deodorant power. The effect is preserved until washed. The spray solution
contains an iodine compound (Iodox-salt) and a liquid conditioning agent andhas been tested for safety to skin, eyes, and mouth. In case of repeated use on amask, it is recommended to wash and dry it before spraying the solution again.

Sprying on aconventional mask

<Caution> depending on the user's utilization and conditions of use, Iodox-spraycannot ensure complete destruction of pathogens.

Disinfection power comparison between a chlorin
based commercial disinfectant and Iodox-spray

Immediate and persistent efficacy
Iodox-‐‑‒spray  eﬀect  of  conventional  mask. .0)
Conventional mask
Nonwoven fabricBacteria solution
added (ml)1No treatment(reference)

I. .0) 20

2UsingIodox-spraytreatment

20. .0)  Bacteria counting
thin film method(CFU/mL)3%

1% %   ) on various pH conditions
Test2H, )disinfecting(7power on a wide pH range
5 (3.3-5.7)[Results] strong
IodoxH3

Reference
Bacteriaload(CFU/ml)
10⁷

107~108
0	
H4.8

Iodox
(Wet)
Bacteria
count
1.0g0

Iodox
(Dry)
Bacteria
count0Cl-based(Wet)
Bacteria
count
10⁴ L
500

Cl-based(Dry)
Bacteriacount
107

Strong	  disinfec1ng	  power	  (eﬀec1ve	  even	  if	  dried)	  103 PBSIodoxH3	
H3.3

Iodox©-spray

4

SCDLP

1010310[Features]	  Ø Long-­‐las1ng	  352 an1bacterial	  and	  an1viral	  power	  *	  Rapid	  inac1va1on	  of	  E.	  coli	  /	  Avian	  inﬂuenza	  virus	  (reduced	  to	  0.5%
less	  than	  1/1.000.000)	  0.2mL

ReedandMuench*	  Disinfec1ng	  power	  preserved	  for	  over	  1	  year	  when	  leI	  at	  room	  EID50temperature	  Ø Iodox-­‐spray	  can	  add	  an1bacterial	  and	  an1viral	  capabili1es	  to	  masks	  and	  clothes,	  and	  the	  eﬀect	  persists	  unless	  washed	  or	  removed.	  
Ø Tested	  for	  safety	  on	  eyes	  and	  skin.	  
2	
H5.7	
H4.1

Iodox-KSo[Antibacterial power/persistence]
Iodox-spray
It can be applied as a spray whenit necessary to assure protection
from infectious diseases. Readilyand easily use, like chlorine-based
disinfectants (but gentler to theskin).
Iodox can also be used outdoor onsoil, since it binds to the soil
components assuring a longlasting disinfection power.

Reference

Cl-based spray（Bacteria load ~107 CFU/mL）

Iodox

Virus reduced to 1/1.000.000〜1/10.000.000
12 wt%

D [ Iodox C (12)-KSo] D [ Iodox B (12)-KSo]

10 minutes
treatment
Iodox
4wt%
D [ Iodox
C (4)-KSo] D [ IodoxDatafromKyoto
SangyoUniversityB [Antiviral(4)-KSo]
D[Ref-KSo]
1
1power](Center for Molecular Research on
1 Iodox
1wt% DInfectious[ Iodox CDiseases)(1)-KSo] D [ Iodox B (1)-KSo]Ø Iodox-spray
D [ Ref-KSo]
1

D [ Iodox H (12)-KSo]

The virus is almost totally eradicated in short timeof various Iodox types
1.Results
Iodox-KSo
10 (iodine loadings) on avian inlfuenza virus
Sample tested
Residual virus titer

D . Iodox C (12)-KSoIodox-spray(Bacteria count 0)*0.5*

D . Iodox C (4)-KSo0.5

D . Iodox C (1)-KSo

1.5

D . Iodox B (12)-KSo

0.5

D . Iodox B (4)-KSo

0.5

D . Iodox B (1)-KSo

1.75

D . Iodox H (12)-KSo

0.5

D . Ref-KSo

4.75

Starting virus load

7.0

Residual virus titer (log10EID50/0.2 mL)