Program for 4th AMMRA meeting (Official Language: English)
2009.12.16 (Wed)Arrival at Kumamoto, Japanl
Hotel: Kumamoto KB Hotel, Honjo 3-2-9, Kumamoto 860-0811, Japan.
Tel: +81-96-362-4711
Indicated as A in the map shown below
Please use the below when you take a taxi or ask the place of KB hotel.
熊本KBホテル（Kumamoto KB Hotel）
熊本市本荘3‐2‐9（Honjo 3-2-9, Kumamoto）
電話番号：096-362-4711

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2009.12.17 (Thur)
0900: Meet you at Kumamoto KB hotel. 5 minutes walk to Institute5 minutes walk from CARD (indicated as B), the meeting place
Instruction for your presentation(1) Oral presentation
Time allocated for plenary session is 60 minutes including 10 min discussion.
T i m e a l l o c a t e d f o r o r a l p r e s e n t a t i o n is 20 minutes including 5 minutes
discussion. Please keep your time. You can bring and use your computer forpresentation. However, please copy your file into USB memory and bring it tous just in case.
(2) Poster presentation
Size of board: 92 cm width and 180 cm length.
At Institute of Resource Development and Analysis, Kumamoto University0930-0940: Opening remarks Yamamura
Mouse mutagenesis session 1
Chair: Dr. Han-Woong Lee (Yonsei University, Seoul)
Dr. Yoichi Gondo (Riken BRC, Tsukuba)
0940-1000:
1-01. MSM/MS mouse as a tool for humanized mouse project in Japan
Ken-ichi Yamamura and Kimi Araki
Institute of Resource Decelopment and Analysis, Center for Animal Development andResources, Kumamoto University, 2-2-1 Honjo, Kumamoto 860-0811, Japan
1000-1020:
1-02. Power of RIKEN gene-driven mouse mutagenesis and ENU mutant mouse
library
Takuya Murata, Shigeru Makino, Ryutaro Fukumura, and Yoichi Gondo
Mutagenesis and Genomics Team, RIKEN BioResource Center, 3-1-1 Koyadai Tsukuba,Ibaraki, 305-0074, Japan1020-1040:
1-03 Genome wide mutagenesis by the piggyBac transposon: an update
Xiaohui Wu and Tian Xu
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Institute of Developmental Biology and Molecular Medicine, Fudan University, 220
Handan Road, Shanghai 200433, China
1040-1100:
1-04. Placenta specific gene manipulation using lentiviral vectors
Masahito Ikawa, Yuka Morioka, and Masaru Okabe
Research Institute for Microbial Diseases, Osaka University, 3-1 Yamada-oka, Suita,Osaka 565-0871, Japan1110-1210:
Plenary session 1
Chair: Yoichi Obata (Riken BRC, Tsukuba)
PL-1. Genetic manipulations in human iPS cells produced by a new platform
Wei Wang1, Hui Liu1, 3, Jian Yang1, Ge Guo2, Roland Rad1, Austin Smith2, Allan Bradley1
and Pentao Liu1
1Wellcome Trust Sanger Institute, Hinxton, Cambridgeshire, CB10 1HH, U.K, 2Wellcome
Trust Centre for Stem Cell Research, University of Cambridge, Cambridge CB2 1QR,U.K, 3College of Animal Science and Technology, Huazhong Agriculture University,Wuhan, China
1210-1330: Lunch
1330-1530
Mouse mutagenesis session 2
Chair: Dr. Goo-Taeg Oh (Ehwa Women’s University)
Dr. Xiang Gao (Nanjing University)
1330-1350:
1-05. The role of SNUR4 on adipogenesis and osteogenesis
Il Yong Kim 1, Yo Na Kim 1,2, ChangYong KO3, Jae Hoon Shin 1, Ji Won Choi 1, Kyung
Jin Roh2, Mi Ra Sohn 4, Cheol Soo Choi 2,5, HanSung Kim3, Yun Soo Bae 4 and Je
Kyung Seong 11
Laboratory of Developmental Biology and Genomics, College of Veterinary Medicine,Seoul National University,Seoul 2Lee Gil Ya Cancer and Diabetes Institute, 3Departmentof biomedical Engineering, College of Health Science, Institute of Medical Engineering,
Yonsei University, Wonju 4 Laboratory of Molecular Biochemistry Division of MolecularLife Sciences Ewha Woman’s University, 5Division of Endocrinology Gil Medical Center,3

Gachon University of Medicine and Science, Incheon, Seoul, Korea
1350-1410:
1-06. Peroxiredoxin II in Aortic Wall Regulates Atherosclerosis by a H2O2dependent Signaling Pathway
Jong-Gil Park1, 3, Ji-Young Yoo1, Sejin Jeong1, Dae-Yeul Yu2, Goo Taeg Oh1
1
Department of Life Sciences, Ewha Womans University, Seoul 120-750, 2 Korea
Research Institute of Bioscience and Biotechnology, 3College of Veterinary Medicine,Seoul National University, Seoul 151-742, Republic of Korea
1410-1430:
1-07 Autophagy delivers trypsinogen to the lysosome in acute pancreatitis
Masaki Ohmuraya1,2, Kimi Araki1, Noboru Mizushima3, Ken-ichi Yamamura1
1
Institute of Resource Development and Analysis and 2Priority Organization for
Innovation and Excellence, Kumamoto University, 2-2-1 Honjo, Kumamoto 860-0811,
Japan 3Department of Physiology and Cell Biology, Tokyo Medical and Dental University,
1-5-45 Yushima, Bunkyo-ku, Tokyo 113-8519, Japan
1430-1450:
1-08 Cyst formation in kidney of the PKD2 transgenic mice
Eun Young Park1, Young Hoon Sung2, Moon Hee Yang1, Kyung Hyun Yoo1, Goo Taeg
Oh3, Je Kyung Seong4, Han-Woong Lee2, and Jong Hoon Park1
1
Department of Biological Science, Sookmyung Women’s University, Seoul 140-742,2
Department of Biochemistry, Yonsei University, Seoul 120-749, 3Division of MolecularLife Sciences, Ewha Womans University, Seoul 120-750, 4College of Veterinary
Medicine, Seoul National University, Seoul 151-742, Republic of Korea
1450-1510:
1-09 Growth factor cascades to regulate organogenesis; Coordinatedurogenital/reproductive organ formation.
Gen YamadaThe Institute of Molecular Embryology and Genetics (IMEG), Kumamoto University, 2-21 Honjo, Kumamoto 860-0811, Japan
1510-1530:
1-10 Germinal cell aplasia in Kif18a mutant male mice due to impaired
chromosome congression and dysregulated BubR1 and CENP-E
Xue-song Liu, Xu-dong Zhao, Xiaoxing Wang, Wei Dai & Zhu-Gang Wang
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Department of Medical Genetics, E-Institutes of Shanghai Universities, Shanghai Jiao
Tong University School of Medicine (SJTUSM), Shanghai 200025, China
Shanghai Research Centre for Model Organisms, Shanghai 201210, China
1545-1730: Move to Aso Mountain (Hotel Greenpia Minamiaso)

1830-2000 Reception
2000Poster session and discussion served with free drinking

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2009.12.18 (Fri)At Hotel Greenpia Minamiaso
0900-1100
Mouse mutagenesis session 3
Chair: Chi-Kuang Leo Wang (National Laboratory Animal Center, Taipei)
Xiaohui Wu (Fudan University, Shanghai)
0900-0920:
2-01. Generation and analysis of oligoadenylate synthetase family genes-deficientmice
Shigeru Kakuta, Reiko Ichikawa and Yoichiro Iwakura
Center for Experimental Medicine and Systems Biology, Institute of Medical Science,
University of Tokyo, 4-6-1 Shirokanedai, Minato-ku, Tokyo 108-8639, Japan
0920-0940:
2-02. Studies on strain dependent phenotypes in HBx transgenic mice
Dae-Yeul Yu
Disease Model Research Laboratory, Korea Research Institute of Bioscience andBiotechnology, 111 Gwahangno, Yuseong-gu, Daejeon 305-806, Korea
0940-1000:
2-03. The Japan Mouse Clinic in RIKEN BRC: Construction of standardized
mouse phenotypic platform and web-based data capturing "PHENO-PUB" system
Tomohiro SUZUKI, Hideki KANEDA, Kimio KOBAYASHI, Ikuo MIURA, Tamio FURUSE,Ikuko YAMADA, Osamu MINOWA, Hideaki TOKI, Hiromi MOTEGI, Maki INOUE, Tetsuo
NODA, Kazunori WAKI, Nobuhiko TANAKA, Hiroshi MASUYA, and Shigeharu WAKANARIKEN BioResource Center, Tsukuba, Ibaraki 305-0074 Japan
1000-1020
2-04. The Taiwan Mouse Clinic: A centralized, but user-friendly phenotyping
facility
Jeffrey J.Y. Yen
Taiwan Mouse Clinic, Institute of Biomedical Sciences, Academia Sinica, Taipei, Taiwan
11529.
1020-1040:
2-05. Toward the integration of mouse phenotype information, technology and6

international cooperation
Hiroshi Masuya1, Nobuhiko Tanaka1, Kazunori Waki1, Riichiro Mizoguchi2, Tetsuro
Toyoda3, Atsushi Yoshiki4, and Shigeharu Wakana5.
1Technology and development unit for knowledge base of mouse phenotype, RIKEN
Bioresource center, 3-1-1 Kouyadai, Tsukuba, Ibaraki 305-0074, 2 Department ofKnowledge Systems, Osaka University, 3 Bioinformatics and systems engineering
division, RIKEN Yokohama Institute, 4 Experimental animal division, RIKEN Bioresource
center, 5Technology and Development Team for Mouse Phenotype Analysis, RIKEN
Bioresource center, Ibaraki 305-0074 Japan
1040-1100:
2-06. Title to be announced
Xiang Gao
Model Animal Research Centre, Nanjing University, 12 Xuefu Road,Pukou High-techDistrict Nanjing 210061, Jiangsu,China
1100-1110 Break1110-1210
Plenary session 2
Chair: Gen Yamada (CARD, Kumamoto)PL-2. KOMP: The U.S. National Institutes of Health Knockout Mouse Project —fromgene-targeted ES cells to knockout mice ready for phenotypic studies
David Frendewey
VelociGene Division, Regeneron Pharmaceuticals, Inc., 777 Old Saw Mill River Road,Tarrrytown, NY 10591, USA
1210-1330: Lunch
1330-1530
Mouse Resource Session
Chair: Kazuo Moriwaki (Riken BRC, Tsukuba)
Zhu-gang Wang (Shanghai Research Center for Model Organisms, Shanghai)
1330-1350: Current status of China mouse resourcesR-1. The cleaning for avoiding disease infection in collection and sharing of7mouse models
Ping XU, Liju LIU, Lily YU
Laboratory Center of Shanghai Institutes for Biological Science, Chinese Academy ofScience, Shanghai 201615, China
1350-1410: Current status of Japan mouse resourcesR-2. Current status of mouse bank in CARD at Kumamoto University
Naomi Nakagata
Center for Animal Resources and Development, Kumamoto University, 2-2-1 Honjo,
Kumamoto 860-0811, Japan
1410-1430: Current status of Japan mouse resourcesR-3. The 2009 progress report of mouse resources at the RIKEN BRCAtsushi Yoshiki, Fumio Ike, Kazuyuki Mekada, Hatsumi Nakata, Noriko Hiraiwa, KeijiMochida, Atsuo Ogura, Yukio Nakamura, Kaoru Fukami-Kobayashi, Kuniya Abe, Kazuo
Moriwaki, and Yuichi Obata
RIKEN BioResource Center
1430-1450: Current status of Taiwan mouse resourcesR-4. Rodent Model Resource Center – The rodent strain resource service inTaiwan region
Chi-Kuang Leo Wang
National Laboratory Animal Center, National Applied Research Laboratories, Nankang,Taipei, 115, Taiwan
1450-1510: Current status of Korea mouse resourcesR-5. Current Status of Korea Mouse Resources
Hyoung-Chin Kim
Animal Model Evaluation Laboratory, Bio-Evaluation Center, Korea Research Institute ofBioscience and Biotechnology, 685-1 Yangcheongri, Ochangmyun, Cheongwongun
Chungcheongbukdo 363-883, Korea
1510-1530: Current status of Singapore mouse resourcesR-6. Current status of Singapore mouse resources
Manickam Arun Kumar
Biological Resources Centre, 20 Biopolis Way, #07-01, Centros, Singapore 138668
1530-1600 Break81600-1730
Open discussion
Chair: Ken-ichi Yamamura (CARD, Kumamoto)
Shigeharu Wakana (Riken BRC, Tsukuba)
1. AMMRA business meeting(1) Organization of AMMRA(2) The 5th AMMRA meeting
2. Future of knockout project(1) Production of knockout ES clones and mice(2) Phenotyping project1) Coordinated effort for phenotyping: Shigeru Wakana (Riken, BRC)
2) Discussion
1830 – 2000: Reception
2000Poster session and discussion served with free drinking

92009.12.19 (Sat)Breakfast
Adjourn
0900 bus for Kumamoto airport, Bus stop for Fukuoka Airport, Kumamoto University andKumamoto railway station(Tour)
0900: Aso mountain or hot spring, then to Kumamoto airport, Bus stop for Fukuoka
Airport, Kumamoto University and Kumamoto railway station.

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