Note: This document has been translated from the Japanese original for reference purposes only. In the event ofany discrepancy between this translated document and the Japanese original, the original shall prevail.

November 9, 2023
CompanyHeadquarters
Representative
Contact
Telephone
WebsiteTakara Bio Inc. (Securities code: 4974;Prime Market)
Nojihigashi 7-4-38, Kusatsu, Shiga, Japan
Koichi Nakao, President & CEO
Takuya Kakemi, Executive Officer, in chargeof PR & IR Department(+81)77-565-6970
https://www.takara-bio.co.jp/Notice Concerning Differences between the Financial Results Forecasts
and the Actual Results

Takara Bio Inc. hereby announces that there had been differences between the financial results forecast forthe six months ended September 30, 2023 (April 1, 2023 – September 30, 2023), disclosed on August 8, 2023,
and the actual results disclosed today, as described below.
1. Differences between the financial results forecasts and the actual results
Differences between consolidated financial results forecasts for the six months ended September 30, 2023 (April1, 2023 – September 30, 2023) and the actual results

Net sales

Operatingprofit

Ordinaryprofit

Net income
attributable toowners ofthe parent

Net income
per share

Million yen

Yen

Million yen

Million yen

Million yen

19,4001,100

1,170650

5.40

Actual results (B)19,116

1,410

1,598

1,084

9.00

Change (B-A)

(283)

310

428

434

-

Change (%)

(1.5)

28.2

36.7

66.8-

32,587

10,87010,955

8,538

70.91

Previously announced
forecasts (A)(Disclosed on August
8, 2023)(Reference)
Actualconsolidated results
for the six months
ended September 30,2022

(2) Reason for differences
Net sales fell short of the previous forecast, but operating income exceeded the previous forecast due to efforts
to reduce SG&A expenses, including R&D expenses. Furthermore, the depreciation of the yen resulted inforeign exchange gains. As a result, ordinary profit and quarterly net income attributable to owners of theparent also differed from forecasts.
For full-year financial result forecasts for the fiscal year ending March 31, 2024, please refer to the "NoticeConcerning Revisions to Financial Results Forecasts" announced today.

Forward-Looking Statements
Statements contained in these materials with respect to the Company’s current plans, forecasts, strategies and beliefs that are
not historical facts are forward-looking statements about the further performance of the Company and its consolidated
subsidiaries. These statements are based on management’s assumptions and beliefs in light of information currently available
to it, but are based on a number of assumptions and beliefs derived from information that contains significant risks anduncertainties. Actual results may differ materially from these forecasts due to various factors. Factors that could influence
actual results include, but are not limited to, economic conditions, especially trends in consumer spending, as well as
exchange rate fluctuations, changes in laws and government systems, pressure from competitors’ prices and productstrategies, declines in selling power of the Company’s existing and new products, disruptions to production, violations of ourintellectual property rights, rapid advances in technology, and unfavorable verdicts in major litigation.