SAFETY DATA SHEETThis safety data sheet was created pursuant to the requirements of:
US OSHA Hazard Communication Standard (29 CFR 1910.1200) and Canada WHMIS
2015 which includes the amended Hazardous Products Act (HPA) and the Hazardous
Products Regulation (HPR)
Revision date 16-Apr-2024

Revision number 2

1. Identification
Product identifier
Product nameElution buffer

Other means of identification
Product code(s)101-633-500

Synonyms

None

Recommended use of the chemical and restrictions on use
Recommended use

See product insert

Restrictions on use

For research use only

Details of the supplier of the safety data sheet
Manufacturer Address
PacBio1305 O’Brien Drive
Menlo Park, CA 94025
USA
www.pacb.com
E-mail address

techsupport@pacb.com

Emergency telephone number
Emergency telephone

CHEMTREC 1-800-424-9300 (CCN#656805)

2. Hazard(s) identification
Classification
This product is not considered hazardous by either the US 2012 OSHA Hazard Communication Standard (29 CFR 1910.1200) or
the Canadian Workplace Hazardous Material Information System (WHMIS 2015).
Label elements
Hazard statements
This product is not considered hazardous by either the US 2012 OSHA Hazard Communication Standard (29 CFR 1910.1200) or
the Canadian Workplace Hazardous Material Information System (WHMIS 2015).

Other information

Page 1 / 8101-633-500

Elution buffer

Revision date 16-Apr-2024

No information available.

3. Composition/information on ingredients
Substance
Not applicable.
MixtureThe product contains no substances which at their given concentration, are considered to be hazardous to health.

4. First-aid measures
Description of first aid measures
Inhalation

Remove to fresh air.

Eye contact

Rinse thoroughly with plenty of water for at least 15 minutes, lifting lower and upper eyelids.
Consult a physician.

Skin contactWash skin with soap and water.

Ingestion

Rinse mouth.

Most important symptoms and effects, both acute and delayed
Symptoms

No information available.

Effects of Exposure

No information available.

Indication of any immediate medical attention and special treatment needed
Note to physicians

Treat symptomatically.

5. Fire-fighting measures
Suitable Extinguishing MediaUse extinguishing measures that are appropriate to local circumstances and thesurrounding environment.

Specific hazards arising from thechemical

No information available.

Explosion data
Sensitivity to mechanical impact None.
None.
Sensitivity to static discharge
Special protective equipment andprecautions for fire-fighters

Firefighters should wear self-contained breathing apparatus and full firefighting turnout gear.
Use personal protection equipment.

6. Accidental release measures
Personal precautions, protective equipment and emergency procedures

Page 2 / 8

101-633-500

Elution buffer

Personal precautions

Revision date 16-Apr-2024

Ensure adequate ventilation.

Methods and material for containment and cleaning up
Methods for containment

Prevent further leakage or spillage if safe to do so.

Methods for cleaning up

Pick up and transfer to properly labeled containers.

7. Handling and storage
Precautions for safe handling
Advice on safe handling

Handle in accordance with good industrial hygiene and safety practice.

Conditions for safe storage, including any incompatibilities
Storage Conditions

Keep containers tightly closed in a dry, cool and well-ventilated place.

8. Exposure controls/personal protection
Control parameters
Exposure Limits

This product, as supplied, does not contain any hazardous materials with occupational
exposure limits established by the region specific regulatory bodies

Appropriate engineering controls
Engineering controls

Showers
Eyewash stations
Ventilation systems.

Individual protection measures, such as personal protective equipment
Eye/face protection

No special protective equipment required.

Hand protection

No special protective equipment required.

Skin and body protection

No special protective equipment required.

Respiratory protection

No protective equipment is needed under normal use conditions. If exposure limits areexceeded or irritation is experienced, ventilation and evacuation may be required.

General hygiene considerations

Handle in accordance with good industrial hygiene and safety practice.

9. Physical and chemical properties
Information on basic physical and chemical properties
LiquidPhysical state
LiquidAppearance

Page 3 / 8101-633-500

Elution buffer

ColorOdor
Odor threshold

Revision date 16-Apr-2024

clear colorless
Odorless
No information available
Remarks • Method
None known
None known
None known
None known
None known
None known

PropertyValues
7 - 8.5pH
No data available
Melting point / freezing point
Initial boiling point and boiling rangeNo data available
No data available
Flash point
No data available
Evaporation rate
Flammability limit in air
Upper flammability or explosive No data available
limitsLower flammability or explosive No data available
limitsNo data available
Vapor pressure
No data available
Relative vapor density
No data available
Relative density
No data available
Water solubility
No data available
Solubility(ies)
No data available
Partition coefficient
No data available
Autoignition temperature
No data available
Decomposition temperature

None known
None known
None known
None known
None known
None known
None known
None known

10. Stability and reactivity
Reactivity

No information available.

Chemical stability

Stable under normal conditions.

Possibility of hazardous reactions

None under normal processing.

Conditions to avoid

None known based on information supplied.

Incompatible materials

None known based on information supplied.

Hazardous decomposition products None known based on information supplied.

11. Toxicological information
Information on likely routes of exposure
Inhalation

Specific test data for the substance or mixture is not available.

Eye contact

Specific test data for the substance or mixture is not available.

Skin contact

Specific test data for the substance or mixture is not available.

Ingestion

Specific test data for the substance or mixture is not available.

Symptoms related to the physical, chemical and toxicological characteristics
Symptoms

No information available.

Acute toxicity.

Numerical measures of toxicity

Page 4 / 8

101-633-500

Elution buffer

Revision date 16-Apr-2024

The following values are calculated based on chapter 3.1 of the GHS document
99,999.00 mg/kg
ATEmix (oral)
99,999.00 mg/kg
ATEmix (dermal)
99,999.00 ppm
ATEmix (inhalation-gas)
99,999.00 mg/l
ATEmix (inhalation-vapor)
ATEmix (inhalation-dust/mist) 99,999.00 mg/l
Delayed and immediate effects as well as chronic effects from short and long-term exposure
Skin corrosion/irritation

No information available.

Serious eye damage/eye irritation

No information available.

Respiratory or skin sensitization

No information available.

Germ cell mutagenicity

No information available.

Carcinogenicity

No information available.

Reproductive toxicity

No information available.

STOT - single exposure

No information available.

STOT - repeated exposure

No information available.

Aspiration hazard

No information available.

12. Ecological information
Ecotoxicity

The environmental impact of this product has not been fully investigated.

Persistence and degradability

No information available.

Bioaccumulation

There is no data for this product.

Other adverse effects

No information available.

13. Disposal considerations
Disposal methods
Waste from residues/unusedproducts

Dispose of in accordance with local regulations. Dispose of waste in accordance withenvironmental legislation.

Contaminated packaging

Do not reuse empty containers.

14. Transport information
DOT

Not regulated

ICAO (air)Not regulated

Page 5 / 8

101-633-500

Elution buffer

Revision date 16-Apr-2024

IATA

Not regulated

IMDG

Not regulated

15. Regulatory information
International InventoriesTSCA

Contact supplier for inventory compliance status.

Chemical name

CAS No.

Inventory Listing Status

Water
Tris-HCl

7732-18-5
1185-53-1

PresentPresent

DSL/NDSL
EINECS/ELINCS
ENCS
IECSC
KECI
PICCS
AIIC
NZIoC

Commercial Activity
Designation
ActiveActiveComplies
Complies
Complies
Complies
Complies
Complies
Complies
Complies

Legend:TSCA - United States Toxic Substances Control Act Section 8(b) Inventory
DSL/NDSL - Canadian Domestic Substances List/Non-Domestic Substances List
EINECS/ELINCS - European Inventory of Existing Chemical Substances/European List of Notified Chemical Substances
ENCS - Japan Existing and New Chemical Substances
IECSC - China Inventory of Existing Chemical Substances
KECL - Korean Existing and Evaluated Chemical Substances
PICCS - Philippines Inventory of Chemicals and Chemical Substances
AIIC - Australian Inventory of Industrial Chemicals
NZIoC - New Zealand Inventory of Chemicals
US Federal Regulations
SARA 313
Section 313 of Title III of the Superfund Amendments and Reauthorization Act of 1986 (SARA). This product does not contain any
chemicals which are subject to the reporting requirements of the Act and Title 40 of the Code of Federal Regulations, Part 372.

SARA 311/312 Hazard Categories
Should this product meet EPCRA 311/312 Tier reporting criteria at 40 CFR 370, refer to Section 2 of this SDS for appropriateclassifications.
CWA (Clean Water Act)
This product does not contain any substances regulated as pollutants pursuant to the Clean Water Act (40 CFR 122.21 and 40
CFR 122.42).
CERCLAThis material, as supplied, does not contain any substances regulated as hazardous substances under the Comprehensive
Environmental Response Compensation and Liability Act (CERCLA) (40 CFR 302) or the Superfund Amendments andReauthorization Act (SARA) (40 CFR 355). There may be specific reporting requirements at the local, regional, or state level
pertaining to releases of this material.
US State Regulations
California Proposition 65
This product does not contain any Proposition 65 chemicals.
U.S. State Right-to-Know Regulations
Chemical name

New Jersey

Massachusetts

Page 6 / 8

Pennsylvania

101-633-500

Elution buffer

Revision date 16-Apr-2024-Water
7732-18-5-

X

U.S. EPA Label Information
EPA Pesticide Registration Number Not applicable

16. Other information
NFPA
HMIS

Health hazards 0
Health hazards 0

Flammability 0
Flammability 0

Instability 0
Physical hazards 0Special hazards Personal protection X

Key or legend to abbreviations and acronyms used in the safety data sheet
Legend Section 8: Exposure controls/personal protection
TWATWA (time-weighted average)
Ceiling
Maximum limit value

STEL
Sk*

STEL (Short Term Exposure Limit)
Skin designation

Key literature references and sources for data used to compile the SDS
Agency for Toxic Substances and Disease Registry (ATSDR)
U.S. Environmental Protection Agency ChemView Database
European Food Safety Authority (EFSA)
Environmental Protection Agency
Acute Exposure Guideline Level(s) (AEGL(s))
U.S. Environmental Protection Agency Federal Insecticide, Fungicide, and Rodenticide Act
U.S. Environmental Protection Agency High Production Volume Chemicals
Food Research Journal
Hazardous Substance Database
International Uniform Chemical Information Database (IUCLID)
National Institute of Technology and Evaluation (NITE)
Australia National Industrial Chemicals Notification and Assessment Scheme (NICNAS)
NIOSH (National Institute for Occupational Safety and Health)National Library of Medicine's ChemID Plus (NLM CIP)
National Library of Medicine’s PubMed database (NLM PUBMED)
U.S. National Toxicology Program (NTP)New Zealand's Chemical Classification and Information Database (CCID)
Organization for Economic Co-operation and Development Environment, Health, and Safety Publications
Organization for Economic Co-operation and Development High Production Volume Chemicals Program
Organization for Economic Co-operation and Development Screening Information Data Set
World Health Organization
Prepared by

PacBioEnvironment, Health, and Safety
1305 O’Brien Drive
Menlo Park, CA 94025
USA
safety@pacb.com.

Revision date

16-Apr-2024

Revision note

No information available

Disclaimer
The above information is believed to be correct but does not purport to be all inclusive and shall be used only as a guide.
The information in this document is based on the present state of our knowledge and is applicable to the product withregard to appropriate safety precautions. It does not represent any guarantee of the properties of the product. It is not a
warranty or quality specification. This information relates only to the specific material designated and may not be valid foruse in combination with any other material or in any other process.Research use only. Not for use in diagnostic
procedures. ©2024, Pacific Biosciences of California, Inc. (“PacBio”). All rights reserved. Information in this document issubject to change without notice. PacBio assumes no responsibility for any errors or omissions in this document. Certain
notices, terms, conditions and/or use restrictions may pertain to your use of PacBio products and/or third-party products.
Refer to the applicable PacBio terms and conditions of sale and to the applicable license terms at pacb.com/license.

Page 7 / 8

101-633-500

Elution buffer

Revision date 16-Apr-2024

Pacific Biosciences, the PacBio logo, PacBio, Circulomics, Omniome, SMRT, SMRTbell, Iso-Seq, Sequel, Nanobind, SBB,Revio, Onso, Apton, Kinnex and PureTarget are trademarks of PacBio.
End of Safety Data SheetPage 8 / 8