CURRICULUM VITAE
Taichi Sakaguchi, M.D., Ph.D.
Sex :

Male

Date of Birth :12 March 1967

Place of Birth :Nara, Japan

Marital State :Married, two children

Nationality :Japanese

Home Address :3-43-3 Aoyamadai, Suita, Osaka 565-0875, Japan

Office Address:

Professor and Chairman
Department of Cardiovascular Surgery
Hyogo Medical University
1-1 Mukogawa-cho, Nishinomiya, Hyogo 663-8501, Japan
Phone 81-798-45-6851, Fax 81-798-45-6853
E-mail: t-sakaguchi@hyo-med.ac.jp

Education
1986-1992
1996-2000

MD: Osaka University Medical School, Osaka Japan
PhD: Osaka University Graduate School, Osaka Japan

Postgraduate Training
1992-1993
Residency: Osaka University Hospital, Japan (Cardiothoracic & General Surgery)1993-1995
Residency: Osaka Koseinenkin Hospital, Japan (General Surgery)1995-1996
Fellowship: Kinan General Hospital , Japan (Cardiothoracic Surgery)1999-2002
Research Fellowship: Columbia University Medical Center, NY, USA
2002-2004
Clinical Fellowship: Columbia University Medical Center, NY, USA (Cardiac Surgery)
Positions and Appointments
2004-2007
Instructor: Columbia University Medical Center, NY, USA (Cardiac Surgery)2007-2009
Assistant Professor: Osaka University Hospital, Osaka, Japan
2009-2012
Associate Professor: Osaka University Hospital, Osaka, Japan
2009-2012
Director: Adult cardiac surgery, Cardiac transplantation and mechanical circulatory support
program: Osaka University Hospital, Osaka, Japan
2012-2018
Assistant hospital director
The Sakakibara Heart Institute of Okayama, Okayama, Japan
2018-present Professor and Chairman
Department of Cardiovascular Surgery, Hyogo College of Medicine, Hyogo, Japan
Certification and Licensure:
National Medical Board of Japan (Medical License, No. 346078) May.1992
ECFMG Certificate (Certificate No. 0-467-857-9)
Jan.2002
Board Certification of Japan Surgical Society (No. 0402706)
Jul.2002
Award:
Vivien Thomas Young Investigator Awards of American Heart Association’s Scientific Sessions (2001,
LA): Finalist
Oversea Fellowship :Uehara Memorial Foundation (Japan, 2002)

Publication
1. Matsuda H, Sawa Y, Sakaguchi T, et al: Minimally invasive cardiac surgery for patients with mitral valve
disease – Initial experience using parasternal approach. Asian J Surg. 22: 3-8, 1999.
2. Sakaguchi T, Sawa Y, Ohtake S, Hirata N, Matsuda H. The freestyle aortic bioprosthesis for prosthetic
valve endocarditis. Ann Thorac Surg. 67: 533-535, 1999.
3. Hayashi Y, Ohtake S, Sawa Y, Nishimura M, Ichikawa H, Satoh H, Yamaguchi T, Suhara H, Sakaguchi T,
Matsuda H: Percutaneous cardiopulmonary support with heparin-coated circuits in postcardiotomy
cardiogenic shock. Efficacy and comparison with left heart bypass. Jpn J Thorac and Cardiovasc Surg. 48:
274-279, 2000.
4. Sakaguchi T, Sawa Y, Kitakaze M, Suzuki K, Nishimura M, Kaneda Y, Matsuda H: Ecto-5’-nucleotidase
plays a role in the cardioprotective effects of heat shock protein 70 in ischemia-reperfusion injury in rat
hearts. Cardiovasc Res. 47: 74-80, 2000.
5. Sawa Y, Fukushima N, Nishimura M, Sakaguchi T, Ohtake S, Matsuda H: Development of new techniques
using genetic and tissue engineering for the treatment of severe heart failure. Transplant Proc. 32: 242-244,
2000.
6. Hayashi Y, Kagizaki K, Yamaguchi T, Sakaguchi T, Naka Y, Sawa Y, Ohtake S, Matsuda H: Clinicalapplication of vacuum-assisted cardiopulmonary bypass with a pressure relief valve. Eur J Cardiothorac
Surg. 20: 621-626, 2001.
7. Okada M, Fujita T, Sakaguchi T, Olson KE, Collins T, Stern DM, Yan SF, Pinsky DJ: Extinguishing Egr-1dependent inflammatory and thrombotic cascades following lung transplantation. FASEB J. 15: 2757-2759,
2001.
8. Sakaguchi T, Sawa Y, Fukushima N, Nishimura M, Ichikawa H, Kaneda Y, Matsuda H: A novel strategy ofdecoy transfection against nuclear factor-kB in myocardial preservation. Ann Thorac Surg. 71: 624-629,
2001.
9. Sakaue G, Shimaoka M, Fukuoka T, Hiroi T, Inoue T, Hashimoto N, Sakaguchi T, Sawa Y, Morishita R,
Kiyono H, Noguchi K, Mashimo T: NF-kappa B decoy suppresses cytokine expression and thermal
hyperalgesia in a rat neuropathic pain model. Neuroreport. 12: 2079-2084, 2001.
10. Okada M, Wang CY, Hwang DW, Sakaguchi T, Olson KE, Yoshikawa Y, Minamoto K, Mazer SP, Yan SF,
Pinsky DJ: Transcriptional control of cardiac allograft vasculopathy by early growth response gene-1 (Egr-1).
Circ Res. 91: 135-142, 2002.
11. Hudson BI, Bucciarelli LG, Wendt T, Sakaguchi T, Lalla E, Qu W, Lu Y, Lee L, Stern DM, Naka Y,
Ramasamy R, Yan SD, Yan SF, D’Agati V, Schmidt AM: Blockade of receptor for advanced glycation
endproducts: a new target for therapeutic intervention in diabetic complications and inflammatory disorders.
Arch of Biochem Biophys. 419: 80-88, 2003 Review.
12. Sakaguchi T, Yan SF, Yan SD, Belov D, Rong LL, Sousa M, Andrassy M, Marso SP, Duda S, Arnold B,
Liliensiek B, Nawroth PP, Stern DM, Schmidt AM, Naka Y: Central role of RAGE-dependent neointimal
expansion in arterial restenosis. J Clin Invest. 111: 959-972, 2003.
13. Asai T, Baron HM, von Bayern MP, Sakaguchi T, Arrecubieta C, Cespedes CA, Lee MH, Lowy FD, Marboe
CC, Deng MC, Naka Y: A mouse aortic patch model for mechanical circulatory support. J Heart Lung
Transplant. 24: 1129-1132, 2005.
14. Dang NC, Aboodi MS, Sakaguchi T, Wasserman HS, Argenziano M, Cosgrove DM, Rosengart TK,
Feldman T, Block PC, Oz MC: Surgical revision after percutaneous mitral valve repair with a clip: initial
multicenter experience. Ann Thorac Surg. 80: 2338-2342, 2005.

15. Sakaguchi T, Asai T, Belov D, Okada M, Pinsky DJ, Schmidt AM, Naka Y: Influence of ischemic injury onvein graft remodeling: Role of cyclic adenosine monophosphate second messenger pathway in enhanced
vein graft preservation. J Thorac Cardiovasc Surg. 129: 129-137, 2005.
16. Asai T, Lee, MH, Arrecubieta C, von Bayern MP, Cespedes CA, Baron HM, Cadeiras M, Sakaguchi T,
Marboe CC, Naka Y, Deng MC, Lowy FD: Cellular coating of the left ventricular assist device textured
polyurethane membrane reduces adhesion of Staphylocuccus aureus. J Thorac Cardiovasc Surg.
133:1147-1153, 2007.
17. Takeda K, Matsumiya G, Matsue H, Hamada S, Sakaki M, Sakaguchi T, Fujita T, Sawa Y: Use ofquantitative analysis of remote myocardial fibrosis with delayed-enhancement magnetic resonance imaging
to predict outcomes after surgical ventricular restoration for ischemic cardiomyopathy. J Thorac Cardiovasc
Surg. 136:1514-1521, 2008.
18. Takeda K, Matsumiya G, Sakaguchi T, Matsue H, Masai T, Otake S, Taniguchi K, Sawa Y: Osaka
Cardiovascular Surgery Research (OSCAR) group. Long-term results of left ventricular reconstructive
surgery in patients with ischemic dilated cardiomyopathy: a multicenter study. Circ J. 72:1730-1736, 2008.
19. Takeda K, Matsumiya G, Matsue H, Sakaki M, Sakaguchi T, Fujita T, Sawa Y. Left ventricular
reconstructive surgery in ischemic dilated cardiomyopathy complicated with cardiogenic shock. Ann Thorac
Surg. 85: 1339-1343, 2008.
20. Yokota T, Ichikawa H, Matsumiya G, Kuratani T, Sakaguchi T, Iwai S, Shirakawa Y, Torikai K, Saito A,
Uchimura E, Kawaguchi N, Matsuura N, Sawa Y: In situ tissue regeneration using a novel tissueengineered, small-caliber vascular graft without cell seeding. J Thorac Cardiovasc Surg. 136: 900-907,
2008.
21. Adachi I, Matsumiya G, Sakaguchi T, Kuratani T, Miyagawa S, Yamauchi T, Saito S, Sawa Y: Ventricularassist device infection necessitating device exchange following extensive myocardial resection. J Artif
Organs. 12: 271-273, 2009.
22. Saito S, Matsumiya G, Ueno T, Sakaguchi T, Kuratani T, Ichikawa H, Sawa Y: Bench replacement ofdonor aortic valve before orthotopic heart transplantation. J Heart Lung Transplant. 28: 981-983, 2009.
23. Saito S, Matsumiya G, Sakaguchi T, Fujita T, Kuratani T, Ichikawa H, Sawa Y: Fifteen-year experience
with Toyobo paracorporeal left ventricular assist system. J Artif Organs. 12: 27-34, 2009.
24. Saito S, Matsumiya G, Sakaguchi T, Fujita T, Kuratani T, Ichikawa H, Sawa Y: Long-term medical control
of inflow cuff infection in a patient with a left ventricular assist system. J Artif Organs. 12: 58-60, 2009.
25. Saito S, Matsumiya G, Fukushima N, Sakaguchi T, Fujita T, Ueno T, Miyagawa S, Yamauchi A, Sawa Y:
Successful treatment of cardiogenic shock caused by humoral cardiac allograft rejection. Circ J. 73: 970973, 2009.
26. Kamata S, Sakaguchi T, Miyagawa S, Yoshikawa Y, Yamauchi T, Takeda K, Saito S, Ueno T, Kuratani T,
Sawa Y: The first clinical case in Japan of destination therapy using the Jarvik 2000 left ventricular assist
device. J Artif Organs. 13: 170-173, 2010.
27. Miyagawa S, Saito A, Sakaguchi T, Yoshikawa Y, Yamauchi T, Imanishi Y, Kawaguchi N, Teramoto N,
Matsuura N, Iida H, Shimizu T, Okano T, Sawa Y: Impaired myocardium regeneration with skeletal cellsheets--a preclinical trial for tissue-engineered regeneration therapy. Transplantation. 90: 364-372, 2010.
28. Saito S, Matsumiya G, Sakaguchi T, Miyagawa S, Yamauchi T, Kuratani T, Sawa Y: Cardiac fibrosis andcellular hypertrophy decrease the degree of reverse remodeling and improvement in cardiac function duringleft ventricular assist. Journal of Heart and Lung Transplantation. 29: 672-679, 2010.
29. Saito S, Matsumiya G, Sakaguchi T, Miyagawa S, Yoshikawa Y, Yamauchi T, Kuratani T, Sawa Y: Risk
factor analysis of long-term support with left ventricular assist system. Circ J. 74: 715-722, 2010.

30. Shudo Y, Matsumiya G, Sakaguchi T, Miyagawa S, Yoshikawa Y, Yamauchi T, Takeda K, Saito S,
Nakatani S, Taniguchi K, Izutani H, Sawa Y: Assessment of changes in mitral valve configuration withmultidetector computed tomography: impact of papillary muscle imbrication and ring annuloplasty.
Circulation. 122: S29-36, 2010.
31. Shudo Y, Matsumiya G, Sakaguchi T, Miyagawa S, Yamauchi T, Takeda K, Saito S, Taniguchi K, Sawa Y:
Impact of surgical ventricular reconstruction for ischemic dilated cardiomyopathy on restrictive filling pattern.
Gen Thorac Cardiovasc Surg. 58: 399-404, 2010.
32. Shudo Y, Taniguchi K, Takeda K, Sakaguchi T, Matsue H, Izutani H, Matsumiya G, Sawa Y: Assessmentof regional myocardial wall stress before and after surgical correction of functional ischaemic mitral
regurgitation using multidetector computed tomography and novel software system. Eur J Cardiothorac
Surg. 38:163-170, 2010.
33. Takeda K, Matsumiya G, Sakaguchi T, Miyagawa S, Yamauchi T, Shudo Y, Izutani H, Sawa Y. Impact of
untreated mild-to-moderate mitral regurgitation at the time of isolated aortic valve replacement on lateadverse outcomes. Eur J Cardiothorac Surg. 37:1033-1038, 2010.
34. Fujita T, Sakaguchi T, Miyagawa S, Saito A, Sekiya N, Izutani H, Sawa Y: Clinical impact of combinedtransplantation of autologous skeletal myoblasts and bone marrow mononuclear cells in patients withseverely deteriorated ischemic cardiomyopathy. Surg Today. 41:1029-1036, 2011.
35. Kainuma S, Taniguchi K, Daimon T, Sakaguchi T, Funatsu T, Kondoh H, Miyagawa S, Takeda K, Shudo Y,
Masai T, Fujita S, Nishino M, Sawa Y; Osaka Cardiovascular Surgery Research (OSCAR) Group. Does
stringent restrictive annuloplasty for functional mitral regurgitation cause functional mitral stenosis andpulmonary hypertension? Circulation. 124: S97-106, 2011.
36. Miyagawa S, Sakaguchi T, Nishi H, Yoshikawa Y, Fukushima S, Saito S, Sawa Y. Recent clinical andexperimental advances in atrial fibrillation. Int Sch Res Notices Cardiology. 2011: 958189, 2011.
37. Saito S, Sakaguchi T, Miyagawa S, Yoshikawa Y, Yamauchi T, Ueno T, Kuratani T, Sawa Y: Biventricularsupport using implantable continuous-flow ventricular assist devices. J Hear Lung Transplant. 30: 475-478,
2011.
38. Saito S, Sakaguchi T, Sawa Y: Clinical report of long-term support with dual Jarvik 2000 biventricularassist device. J Hear Lung Transplant. 30: 845-847, 2011.
39. Shudo Y, Matsumiya G, Sakaguchi T, Fujita T, Yamauchi T, Sawa Y: Resection of advanced stage
malignant retroperitoneal neoplasms with tumor thrombus extending into the right atrium: report of fourcases. Surg Today. 41: 262-265, 2011.
40. Shudo Y, Taniguchi K, Takeda K, Sakaguchi T, Funatsu T, Matsue H, Miyagawa S, Kondoh H, Kainuma S,
Kubo K, Hamada S, Izutani H, Sawa Y: Restrictive mitral annuloplasty with or without surgical ventricular
restoration in ischemic dilated cardiomyopathy with severe mitral regurgitation. Circulation. 124: S107-114,
2011.
41. Takeda K, Matsumiya G, Hamada S, Sakaguchi T, Miyagawa S, Yamauchi T, Sawa Y: Left ventricularbasal myocardial scarring detected by delayed enhancement magnetic resonance imaging predicts
outcomes after surgical therapies for patients with ischemic mitral regurgitation and left ventricular
dysfunction. Circ J. 75: 148-156, 2011.
42. Ueno T, Fukushima N, Sakaguchi T, Ide H, Ozawa H, Saito S, Ichikawa H, Sawa Y: First pediatric hearttransplantation from a pediatric donor heart in Japan. Circ J. 76: 752-754, 2012.
43. Kainuma S, Sakaguchi T, Saito S, Miyagawa S, Yoshikawa Y, Yamauchi T, Sakata Y, Takahashi A,
Uehata T, Kuratani T, Sawa Y: Implantation of a Jarvik 2000 left ventricular assist device as a bridge toeligibility for refractory heart failure with renal dysfunction. J Artif Organs. 15: 83-86, 2012.

44. Kainuma S, Taniguchi K, Daimon T, Sakaguchi T, Funatsu T, Miyagawa S, Kondoh H, Takeda K, Shudo Y,
Masai T, Ohishi M, Sawa Y: Mitral valve repair for medically refractory functional mitral regurgitation inpatients with end-stage renal disease and advanced heart failure. Circulation. 126: S205-213, 2012.
45. Kawamura M, Sakaguchi T, Yoshikawa Y, Sawa Y: A Case of Mobile and Massive Calcifications in the Left
Ventricle with Unknown Etiology. J Card Surg. 27: 303-306, 2012.
46. Kawamura M, Sakaguchi T, Miyagawa S, Nishi H, Yoshikawa Y, Fukushima S, Saito S, Ueno T, Kuratani T,
Sawa Y: Exchange of DuraHeart left ventricular assist device via a subcostal approach. J Artif Organs. 15:
87-89, 2012.
47. Miki K, Uenaka H, Saito A, Miyagawa S, Sakaguchi T, Higuchi T, Shimizu T, Okano T, Yamanaka S, Sawa
Y: Bioengineered myocardium derived from induced pluripotent stem cells improves cardiac function andattenuates cardiac remodeling following chronic myocardial infarction in rats. Stem Cells Translational
Medicine 1: 430-437, 2012.
48. Nishi H, Sakaguchi T, Miyagawa S, Yoshikawa Y, Fukushima S, Sumitsuji S, Sawa Y: Failed Depiction ofPatent Bypass Graft Due to Presence of Large Lateral Costal Artery. Ann Thorac Cardiovasc Surg. 18: 275277, 2012.
49. Nishi H, Sakaguchi T, Miyagawa S, Yoshikawa Y, Sawa Y: Cardiac Surgery in Patients with Gilbert's
Syndrome. J Card Surg. 27: 60-61, 2012.
50. Nishi H, Sakaguchi T, Miyagawa S, Yoshikawa Y, Fukushima S, Saito S, Ueno T, Kuratani T, Sawa Y:
Frequency, risk factors and prognosis of postoperative hyperbilirubinemia after heart valve surgery.
Cardiology. 122: 12-19, 2012.
51. Saito S, Sakaguchi T, Miyagawa S, Nishi H, Yoshikawa Y, Fukushima S, Daimon T, Sawa Y. Recovery ofright heart function with temporary right ventricular assist using a centrifugal pump in patients with severe
biventricular failure. Journal of Heart and Lung Transplantation. 31: 858-64, 2012.
52. Saito S, Miyagawa S, Sakaguchi T, Imanishi Y, Iseoka H, Nishi H, Yoshikawa Y, Fukushima S, Saito A,
Shimizu T, Okano T, Sawa Y: Myoblast sheet can prevent the impairment of cardiac diastolic function andlate remodeling after left ventricular restoration in ischemic cardiomyopathy. Transplantation. 93: 1108-1015,
2012.
53. Sawa Y, Miyagawa S, Sakaguchi T, Fujita T, Matsuyama A, Saito A, Shimizu T, Okano T: Tissue
engineered myoblast sheets improved cardiac function sufficiently to discontinue LVAS in a patient with
DCM: report of a case. Surg Today. 42: 181-184, 2012.
54. Shudo Y, Nakatani S, Sakaguchi T, Miyagawa S, Yoshikawa Y, Takeda K, Saito S, Takeda Y, Sakata Y,
Yamamoto K, Sawa Y: Left ventricular mechanics following restrictive mitral annuloplasty for functional
mitral regurgitation: two-dimensional speckle tracking echocardiographic study. Echocardiography. 29: 445450, 2012.
55. Shudo Y, Taniguchi K, Takeda K, Sakaguchi T, Funatsu T, Kondoh H, Sawa Y: Serial multidetector
computed tomography assessment of left ventricular reverse remodeling, mass, and regional wall stressafter restrictive mitral annuloplasty in dilated cardiomyopathy. J Thorac Cardiovasc Surg. 143: S43-47,
2012.
56. Takeda K, Sakaguchi T, Miyagawa S, Shudo Y, Kainuma S, Masai T, Taniguchi K, Sawa Y: The extent ofearly left ventricular reverse remodelling is related to midterm outcomes after restrictive mitral annuloplasty
in patients with non-ischaemic dilated cardiomyopathy and functional mitral regurgitation. Eur J
Cardiothorac Surg. 41: 506-511, 2012.
57. Yamauchi T, Miyata H, Sakaguchi T, Miyagawa S, Yoshikawa Y, Takeda K, Motomura N, Tsukihara H,
Sawa Y: Coronary artery bypass grafting in hemodialysis-dependent patients: analysis of Japan Adult
Cardiovascular Surgery Database. Circ J. 76: 1115-1120, 2012.

58. Yoshioka D, Sakaguchi T, Saito S, Miyagawa S, Nishi H, Yoshikawa Y, Fukushima S, Ueno T, Kuratani T,
Sawa Y: Initial Experience of Conversion of Toyobo Paracorporeal Left Ventricular Assist Device to
DuraHeart Left Ventricular Assist Device. Circ J. 76: 372-376, 2012.
59. Yoshioka D, Sakaguchi T, Yamauchi T, Okazaki S, Miyagawa S, Nishi H, Yoshikawa Y, Fukushima S,
Saito S, Sawa Y: Impact of Early Surgical Treatment on Postoperative Neurologic Outcome for Active
Infective Endocarditis Complicated by Cerebral Infarction. Ann Thorac Surg. 94: 489-496, 2012.
60. Yoshioka D, Sakaguchi T, Saito S, Miyagawa S, Nishi H, Yoshikawa Y, Fukushima S, Saito T, Daimon T,
Ueno T, Kuratani T, Sawa Y: Predictor of early mortality for severe heart failure patients with left ventricularassist device implantation. Circ J. 76: 1631-1638, 2012.
61. Chikazawa G, Yoshitaka H, Hiraoka A, Tanaka K, Mouri N, Tamura K, Totsugawa T, Ishida A, Sakaguchi
T: Preoperative Coil Embolization to Aortic Branched Vessels for Prevention of Aneurysmal Sac
Enlargement Following EVAR: Early Clinical Result. Ann Vasc Dis. 6: 175-179, 2013.
62. Kawamura T, Sakaguchi T, Nishi H, Miyagawa S, Yoshikawa Y, Yamauchi T, Fukushima S, Saito S, Sawa
Y: Successful treatment of a large primary cardiac lymphoma by surgical resection combined withchemotherapy: report of a case. Surg Today. 43: 1066-1070, 2013.
63. Kubota Y, Sakaguchi T, Miyagawa S, Nishi H, Yoshikawa Y, Fukushima S, Saito S, Sawa Y: Successful
management of complex open heart surgery in a patient with Child-Pugh class C liver cirrhosis: report of acase. Surg Today. 43: 335-338, 2013.
64. Nishi H, Toda K, Miyagawa S, Yoshikawa Y, Fukushima S, Yoshioka D, Saito T, Saito S, Sakaguchi T,
Ueno T, Kuratani T, Sawa Y: Prediction of outcome in patients with liver dysfunction after left ventricularassist device implantation. J Artif Organs. 16: 404-410, 2013.
65. Nakatani D, Kotani J, Tachibana K, Ichibori Y, Mizote I, Asano Y, Sakata Y, Sakata Y, Sumitsuji S, Saito S,
Sakaguchi T, Fukushima N, Nanto S, Sawa Y, Komuro I: Plaque regression associated with everolimus
administration after heart transplantation. J Card Cases. 7: e155-e157, 2013.
66. Nishi H, Sakaguchi T, Miyagawa S, Yoshikawa Y, Fukushima S, Saito S, Ueno T, Kuratani T, Sawa Y:
Atrial fibrillation occurring early after cardiovascular surgery: impact of the surgical procedure. Surg Today.
43: 1134-1139, 2013.
67. Nishi H, Sakaguchi T, Miyagawa S, Yoshikawa Y, Fukushima S, Saito S, Ueno T, Kuratani T, Sawa Y:
Impact of microRNA expression in human atrial tissue in patients with atrial fibrillation undergoing cardiac
surgery. PLoS One 8: e73397, 2013.
68. Nishi H, Sakaguchi T, Miyagawa S, Yoshikawa Y, Fukushima S, Saito S, Ueno T, Kuratani T, Sawa Y:
Efficacy of landiolol hydrochloride for atrial fibrillation after open heart surgery. Heart Vessels 28: 490-496,
2013.
69. Sakaguchi T, Nishi H, Miyagawa S, Yoshikawa Y, Fukushima S, Yoshioka D, Ueno T, Sawa Y: One-knot
technique: a simple modification of the loop technique for mitral valve repair. Surg Today. 43: 705-707,
2013.
70. Sakaguchi T, Miyagawa S, Nishi H, Yoshikawa Y, Fukushima S, Saito S, Sawa Y: Rupture of valsalva
sinus after aortic root replacement with Freestyle stentless bioprosthesis. Ann Thorac Surg. 95: 1074-1076,
2013.
71. Sakaguchi T, Saito S, Yoshioka D, Sawa Y: Long-term biventricular support with rotary blood pumps in apatient with a noncontractile heart. J Thorac Cardiovasc Surg. 146: e29-30, 2013.
72. Sakaguchi T, Matsumiya G, Yoshioka D, Miyagawa S, Nishi H, Yoshikawa Y, Fukushima S, Saito S, Ueno
T, Sawa Y: DuraHeart™ magnetically levitated left ventricular assist device: Osaka University experience.
Circ J. 77: 1736-1741, 2013.

73. Saito S, Sakaguchi T, Miyagawa S, Nishi H, Yoshikawa Y, Fukushima S, Yoshioka D, Ueno T, Kuratani T,
Sawa Y: Jarvik 2000 biventricular assist device conversion from old pin-shaped bearing pumps to new
conical bearing pumps. J Artif Organs. 16: 105-109, 2013.
74. Saito S, Matsumiya G, Sakaguchi T, Ueno T, Kuratani T, Sawa Y: Less invasive radial artery harvesting
without endoscopy. Gen Thorac Cardiovasc Surg. 61: 55-56, 2013.
75. Sawa Y, Matsumiya G, Shigemura S, Nishi H, Ichikawa H, Minami M, Fukushima N, Inoue M, Ueno T,
Sawabata A, Sakaguchi T, Saito S, Okumura M: The first successful heart-lung transplantation in Japan:
report of a case. SurgToday. 43: 1461-1466, 2013.
76. Shudo Y, Miyagawa S, Nakatani S, Fukushima S, Sakaguchi T, Saito A, Asanuma T, Kawaguchi N,
Matsuura N, Shimizu T, Okano T, Sawa Y: Myocardial layer-specific effect of myoblast cell-sheet
implantation evaluated by tissue strain imaging. Circ J. 77:1063-1072, 2013.
77. Siegrist PT, Sumitsuji S, Osuga K, Sakaguchi T, Tachibana K, Nanto S: Endovascular coil embolization ofBehçet disease-related giant aneurysm of the right coronary artery after failure of surgical suture. JACC
Cardiovasc Interv. 6: e31-32, 2013.
78. Tanaka K, Yoshitaka H, Chikazawa G, Sakaguchi T, Totsugawa T, Tamura K: Hybrid repair of right aorticarch aneurysm with a Kommerell's diverticulum. Asian Cardiovasc Thorac Ann. 22: 725-727, 2013.
79. Tanaka K, Sakaguchi T, Chikazawa G, Totsugawa T, Yoshitaka. Left ventricular thrombectomy using
video-assisted thoracoscopy. J Card Surg. 28: 117-119, 2013.
80. Tamura K, Yoshitaka H, Totsugawa T, Tsushima Y, Chikazawa G, Ohno T, Sakaguchi T: Bridge use ofendovascular repair and delayed open operation for infected aneurysm of aortic arch. Ann Thorac Surg. 96:
1471-1473, 2013.
81. Yoshioka D, Toda K, Sakaguchi T, Miyagawa S, Nishi H, Yoshikawa Y, Fukushima S, Saito S, Saito T,
Shibasaki I, Sakata Y, Ohtani T, Sawa Y: Initial report of bridge to recovery in a patient with DuraHeart
LVAD. J Artif Organs. 16: 386-388, 2013.
82. Chikazawa G, Hiraoka A, Totsugawa T, Tamura K, Ishida A, Sakaguchi T, Yoshitaka H: Influencing factors
for abdominal aortic aneurysm sac shrinkage and enlargement after EVAR: Clinical reviews before
introduction of preoperative coil embolization. Ann Vasc Dis. 7: 280-285, 2013.
83. Chikazawa G, Hiraoka A, Hirai Y, Tamura K, Totsugawa T, Ishida A, Sakaguchi T, Yoshitaka H: Open
reintervention for aneurysmal sac enlargement after EVAR. Ann Vasc Dis. 7: 350-353, 2013.
84. Hiraoka A, Chikazawa G, Totsugawa T, Tamura K, Sakaguchi T, Nakajima K, Yoshitaka H: Efficacy of rightaxillary artery perfusion for antegrade cerebral perfusion in open total arch repair. J Vasc Surg. 60: 436-442,
2014.
85. Hiraoka A, Chikazawa G, Totsugawa T, Kuinose M, Tamura K, Sakaguchi T, Yoshitaka H: Open total
aortic arch reconstruction for patients with advanced age in the era of endovascular repair. J Thorac
Cardiovasc Surg. 148: 77-82, 2014.
86. Hiraoka A, Chikazawa G, Totsugawa T, Sakaguchi T, Tamura K, Yoshitaka H: Acute kidney injury after
total aortic arch repair with moderate hypothermic circulatory arrest. J Card Surg. 29: 218-224, 2014.
87. Hiraoka A, Totsugawa T, Kuinose M, Nakajima K, Chikazawa G, Tamura K, Yoshitaka H, Sakaguchi T:
Propensity score-matched analysis of minimally invasive aortic valve replacement. Circ J. 78: 2876-2881,
2014.
88. Kainuma S, Taniguchi K, Toda K, Funatsu T, Miyagawa S, Kondoh H, Masai T, Otake S, Yoshikawa Y,
Nishi H, Sakaguchi T, Ueno T, Kuratani T, Daimon T, Sawa Y: Restrictive mitral annuloplasty with orwithout surgical ventricular reconstruction in ischaemic cardiomyopathy: impacts on neurohormonal
activation, reverse left ventricular remodelling and survival. Eur J Heart Fail. 16: 189-200, 2014.

89. Maeda K, Nishi H, Sakaguchi T, Miyagawa S, Ueno T, Kuratani T, Sawa Y: Coronary Artery Bypass
Grafting in a Patient Initially Presenting with Systemic Lupus Erythematosus. Ann Thorac Cardiovasc Surg.
20: 414-417, 2014.
90. Nagata T, Hiraoka A, Sakaguchi T, Yoshitaka H: Acquired pulmonary artery stenosis due to compression
by a calcified pericardial ring encircling the atrioventricular groove. J Am Coll Cardiol. 63: 938, 2014.
91. Nishi H, Toda K, Miyagawa S, Yoshikawa Y, Fukushima S, Saito S, Yoshioka D, Saito T, Ueno T,
Sakaguchi T, Sawa Y: Initial experience in Japan with HeartWare ventricular assist system. J Artif Organs.
17: 149-156, 2014.
92. Nishi H, Sakaguchi T, Miyagawa S, Yoshikawa Y, Fukushima S, Yoshioka D, Saito T, Toda K, Sawa Y:
Optimal coronary artery bypass grafting strategy for acute coronary syndrome. Gen Thorac Cardiovasc
Surg. 62: 357-363, 2014.
93. Nishi H, Sakaguchi T, Miyagawa S, Yoshikawa Y, Fukushima S, Yoshioka D, Ueno T, Kuratani T, Sawa Y:
Factors affecting a dilated ascending aorta in patients with bicuspid aortic valve: the relevance of valve
anatomy, body size and age. Surg Today. 44: 1483-1489, 2014.
94. Tanaka K, Chikazawa G, Sakaguchi T, Totsugawa T, Tamura K, Yoshitaka H: Hybrid treatment for type aacute aortic dissection with multiorgan malperfusion. Ann Thorac Surg. 98: 1118-1120, 2014.
95. Tanaka K, Yoshitaka H, Chikazawa G, Sakaguchi T, Totsugawa T, Tamura K: Hybrid repair of right aorticarch aneurysm with a Kommerell’s diverticulum. Asian Cardiovasc Thorac Ann. 22: 725-727, 2014.
96. Totsugawa T, Kuinose M, Hiraoka A, Yoshitaka H, Tamura K, Sakaguchi T: Anterolateral approach forminimally invasive aortic valve replacement. Gen Thorac Cardiovasc Surg. 62: 290-295, 2014.
97. Yoshioka D, Matsumiya G, Toda K, Sakaguchi T, Yoshikawa Y, Saito S, Matsuda H, Sawa Y: Clinicalresults with Jarvik 2000 axial flow left ventricular assist device: Osaka University Experience. J Artif Organs.
17: 308-314, 2014.
98. Yoshioka D, Toda K, Sakaguchi T, Okazaki S, Yamauchi T, Miyagawa S, Nishi H, Yoshikawa Y,
Fukushima S, Saito T, Sawa Y; OSCAR study group: Valve surgery in active endocarditis patientscomplicated by intracranial haemorrhage: the influence of the timing of surgery on neurological outcomes.
Eur J Cardiothorac Surg. 45: 1082-1088, 2014.
99. Hiraoka A, Chikazawa G, Ishida A, Miyake K, Totsugawa T, Tamura K, Sakaguchi T, Yoshitaka H: Impactof age and intraluminal thrombus volume on abdominal aortic aneurysm sac enlargement after
endovascular repair. Ann Vasc Surg. 29: 1440-1446, 2015.
100. Hiraoka A, Chikazawa G, Tamura K, Totsugawa T, Sakaguchi T, Yoshitaka H: Clinical outcomes ofdifferent approaches to aortic arch disease. J Vasc Surg. 61: 88-95, 2015.
101. Kainuma S, Kasegawa H, Miyagawa S, Nishi H, Yaku H, Takanashi S, Hashimoto K, Okada Y, Nakatani
S, Umezu M, Daimon T, Sakaguchi T, Toda K, Sawa Y; Committee of the Japanese Society of Stentless
Mitral Valve: In vivo assessment of novel stentless valve in the mitral position. Circ J. 79: 553-559, 2015.
102. Kainuma S, Mitsuno M, Toda K, Funatsu T, Nakamura T, Miyagawa S, Yoshikawa Y, Fukushima S,
Yoshioka D, Saito T, Nishi H, Takahashi T, Sakaki M, Monta O, Matsue H, Masai T, Sakaguchi T,
Yoshitaka H, Ueno T, Kuratani T, Daimon T, Taniguchi K, Miyamoto Y, Sawa Y; Osaka Cardiovascular
Surgery Research (OSCAR) Group: Dilated left atrium as a predictor of late outcome after pulmonary vein
isolation concomitant with aortic valve replacement and/or coronary artery bypass grafting. Eur J
Cardiothorac Surg. 48: 765-777, 2015.
103. Kihara K, Tamura K, Chikazawa G, Sakaguchi T, Totsugawa T, Yoshitaka H: Hybrid Three-Stage
Repair for Extended Thoracoabdominal Aortic Aneurysm: Report of A Case. Ann Vasc Dis. 8: 106-109,2015.

104. Matsuo T, Sakaguchi T, Ishida A, Yuguchi S, Saito K, Nakajima M, Ujikawa T, Morisawa T, Chikazawa
G, Takahashi T: Effect of in-hospital physical activity on cardiovascular prognosis in lower extremity bypass
for claudication. J Phys Ther Sci. 27: 1855-1859, 2015.
105. Tanaka K, Yoshitaka H, Chikazawa G, Sakaguchi T, Totsugawa T, Tamura K: Investigation of thesurgical complications during thoracic endovascular aortic repair: experiences with 148 consecutive cases
treated at a single institution in Japan. Surg Today. 45: 22-28, 2015.
106. Tamura K, Nakajima K, Chikazawa G, Hiraoka A, Totsugawa T, Sakaguchi T, Yoshitaka H:
Effectiveness of the Use of Near-Infrared Spectroscopy to Treat Acute Type A Aortic Dissection
Complicated with Limb Ischemia: Report of a Case. Ann Vasc Dis. 8: 249-51, 2015.
107. Totsugawa T, Sakaguchi T, Hiraoka A, Matsushita H, Hirai Y, Yoshitaka H: Minimally Invasive
Transaortic Mitral Decalcification During Aortic Valve Replacement. Innovations. 10: 288-90, 2015.
108. Yoshioka D, Toda K, Okazaki S, Sakaguchi T, Miyagawa S, Yoshikawa Y; OSCAR Study Group, Sawa
Y: Anemia Is a Risk Factor of New Intraoperative Hemorrhagic Stroke During Valve Surgery for
Endocarditis. Ann Thorac Surg. 100: 16-23, 2015.
109. Hiraoka A, Chikazawa G, Sakaguchi T, Yoshitaka H. Late leakage from four-branch prosthetic graft
after total aortic arch repair. Eur J Cardiothorac Surg. 49: e31-2, 2016.
110. Irisawa Y, Hiraoka A, Totsugawa T, Chikazawa G, Nakajima K, Tamura K, Yoshitaka H, Sakaguchi T:
Re-expansion pulmonary oedema after minimally invasive cardiac surgery with right mini-thoracotomy†. Eur
J Cardiothorac Surg. 49: 500-505, 2016.
111. Sakaguchi T, Totsugawa T, Tamura K, Yoshitaka H: Extended neochord weaving technique fordegenerative mitral valve disease. J Thorac Cardiovasc Surg. 152: 1626-1628, 2016.
112. Sakaguchi T. Minimally invasive mitral valve surgery through a right mini-thoracotomy. Gen Thorac
Cardiovasc Surg. 64: 699-706, 2016.
113. Suzuki K, Totsugawa T, Hiraoka A, Tamura K, Chikazawa G, Ishida A, Sakaguchi T, Yoshitaka H: A
Left Ventricular Thrombus in a Patient With Primary Antiphospholipid Syndrome Removed Under
Thoracoscopic Support. Ann Thorac Surg. 102:e109-11, 2016.
114. Tamura K, Kihara K, Chikazawa G, Sakaguchi T, Yoshitaka H. A Case of Dissection and Rupture of theInnominate Artery in Acute Type A Aortic Dissection. Ann Vasc Dis. 9: 117-9, 2016.
115. Tanaka K, Sakaguchi T, Ota K, Takano H: Surgical repair of isolated anterior mitral leaflet cleft via rightminithoracotomy. J Cariol Cases. 13: 196-198, 2016.
116. Totsugawa T, Sakaguchi T, Hiraoka A, Irisawa Y, Maeda K, Yoshitaka H. Hypertrophic aortic branches
can potentially cause critical problems during minimally invasive cardiac surgery. Gen Thorac Cardiovasc
Surg. 64: 10-3, 2016.
117. Chikazawa G, Hiraoka A, Inoue K, Tamura K, Sakaguchi T, Yoshitaka H. Aortic arch banding procedure
for proximal type I endoleak after thoracic endovascular aneurysm repair with the chimney technique. J
Vasc Surg Cases Innov Tech. 3: 228-231, 2017.
118. Hiraoka A, Chikazawa G, Totsugawa T, Tamura K, Ishida A, Sakaguchi T, Yoshitaka H: Objective
analysis of midterm outcomes of conventional and hybrid aortic arch repair by propensity-score matching. J
Thorac Cardiovasc Surg. 154: 100-106, 2017.
119. Hiraoka A, Chikazawa G, Ishida A, Totsugawa T, Tamura K, Sakaguchi T, Yoshitaka H. Preoperative
Coil Embolization of Side Branches and Postoperative Antifibrinolytic Therapy in Endovascular Aneurysm
Repair: A Propensity Score Analysis. J Vasc Interv Radiol. 28: 550-557, 2017.

120. Hiraoka A, Suzuki K, Chikazawa G, Nogami S, Sakaguchi T, Yoshitaka H. Adaptive servo-ventilation
suppresses elevation of C-reactive protein and sympathetic activity in acute uncomplicated type B aortic
dissection. Interact Cardiovasc Thorac Surg. 24: 27-33, 2017.
121. Hiraoka A, Fukushima S, Miyagawa S, Yoshikawa Y, Saito S, Domae K, Sakaguchi T, Toda K, Sawa Y.
Quantity and quality of graft flow in coronary artery bypass grafting is associated with cardiac computed
tomography study-based anatomical and functional parameters. Eur J Cardiothorac Surg. 52: 909-916,
2017.
122. Ishida M, Sakaguchi T, Miyagawa S, Nishi H, Yoshikawa Y, Fukushima S, Kawamura A, Ueno
T, Ishibashi-Ueda H, Sawa Y. Right Ventricular Outflow Tract Obstruction Due to Immunoglobulin G4Related Disease. Ann Thorac Surg. 103 :e235-e237. 2017.
123. Kagiyama N, Nakazato T, Yoshida K, Sakaguchi T: Importance of detailed distribution of branches ingiant coronary aneurysm. Eur J Cardiothorac Surg. 51: 394, 2017.
124. Kagiyama N, Toki M, Hayashida A, Ohara M, Hirohata A, Yamamoto K, Totsugawa T, Sakaguchi T,
Yoshida K, Isobe M. Prolapse volume to prolapse height ratio for differentiating Barlow’s disease fromfibroelastic deficiency. Circ J. 81: 1730-1735, 2017.
125. Kondo N, Totsugawa T, Hiraoka A, Tamura K, Yoshitaka H, Sakaguchi T: Left Atrial Appendage
Resection During Minimally Invasive Aortic Valve Surgery via Right Minithoracotomy. Innovations. 12: 378379, 2017.
126. Kondo N, Tamura K, Sakaguchi T, Chikazawa G, Yoshitaka H. Replacement of the Thoracoabdominal
Aorta after Endovascular Abdominal Aneurysm Repair for Ruptured Infected Aneurysm: A Case Report.
Ann Vasc Dis. 10: 63-65, 2017.
127. Nakajima M, Totsugawa T, Sakaguchi T, Yuguchi S, Matsuo T, Ujikawa T, Morisawa T, Takahashi T:
Changes in the amount of physical activity in minimally invasive cardiac surgery. J Phys Ther Sci. 29: 20352038, 2017.
128. Shudo Y, Miyagawa S, Ohkura H, Fukushima S, Saito A, Kawaguchi N, Matsuura N, Toda
K, Sakaguchi T, Nishi H, Yoshikawa Y, Shimizu T, Okano T, Matsuyama A, Sawa Y. Adipose tissuederived multi-lineage progenitor cells improve left ventricular dysfunction in porcine ischemic
cardiomyopathy model. J Heart Lung Transplant. 36: 237-239, 2017.
129. Tamura K, Chikazawa G, Hiraoka A, Totsugawa T, Sakaguchi T, Yoshitaka H. The prognostic impact of
distal anastomotic new entry after acute type I aortic dissection repair. Eur J Cardiothorac Surg. 52: 867873, 2017.
130. Totsugawa T, Hiraoka A, Tamura K, Yoshitaka H, Sakaguchi T: Easy Placement of Annular Sutures
During Minimally Invasive Aortic Valve Replacement. Innovations. 12 :227-229, 2017.
131. Totsugawa T, Hiraoka A, Tamura K, Yoshitaka H, Sakaguchi T: Clamp Ablation of Pulmonary Veins
During Minimally Invasive Aortic Valve Replacement. Ann Thorac Surg. 104 :e471-e473, 2017.
132. Totsugawa T, Suzuki K, Hiraoka A, Tamura K, Yoshitaka H, Sakaguchi T: Concomitant septal
myectomy during minimally invasive aortic valve replacement through a right mini-thoracotomy for thetreatment of aortic stenosis with systolic anterior motion of the mitral valve. Gen Thorac Cardiovasc Surg.
65: 657-660, 2017.

133. Yoshioka D, Toda K, Yokoyama JY, Matsuura R, Miyagawa S, Shirakawa Y, Takahashi T, Sakaguchi
T, Fukuda H, Sawa Y. Recent Surgical Results for Active Endocarditis Complicated With Perivalvular
Abscess. Circ J. 81: 1721-1729, 2017.
134. Hari Y, Hiraoka A, Yositaka H, Sakaguchi T: Computed tomography showing formation of caseous
calcification of the mitral annulus over time. Int J Cardiovasc Imaging. 2018; 34: 1471-1472.
135. Hiraoka A, Shiraya S, Chikazawa G, Ishida A, Miyake K, Sakaguchi T, Yoshitaka H. Feasibility of threedimensional fusion imaging with multimodality roadmap system during endovascular aortic repair. J Vasc
Surg. 2018; 68: 1175-1182.
136. Hiraoka A, Saito K, Chikazawa G, Totsugawa T, Tamura K, Ishida A, Sakaguchi T, Yoshitaka H.
Modified predictive score based on frailty for mid-term outcomes in open total aortic arch surgery. Eur J
Cardiothorac Surg. 2018; 54: 42-47.
137. Inoue K, Ueno T, Hiraoka A, Sakaguchi T. Combined minimally invasive repair of the adult form of thescimitar syndrome and organic mitral regurgitation. Interact Cardiovasc Thorac Surg. 2018; 26: 1037-1038.
138. Muraki R, Hiraoka A, Nagata K, Nakajima K, Oshita T, Arimichi M, Chikazawa G, Yoshitaka H,
Sakaguchi T. Novel method for estimating the total blood volume: The importance of adjustment using theideal body weight and age for the accurate prediction of hemodilution during cardiopulmonary bypass.
Interact Cardiovasc Thorac Surg. 2018; 27: 802-807.
139. Sakaguchi T, Totsugawa T, Tamura K, Hiraoka A, Chikazawa G, Yoshitaka H. Minimally invasive transmitral septal myectomy for diffuse-type hypertrophic obstructive cardiomyopathy. Gen Thorac Cardiovasc
Surg. 2018. doi: 10.1007/s11748-018-0908-z. [Epub ahead of print].
140. Sakaguchi T, Akagi S, Totsugawa T, Tamura K, Hiraoka A. Right ventricular pseudoaneurysm. Eur
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141. Sakaguchi T, Totsugawa T, Tamura K, Hiraoka A, Inoue K. Caseous calcification of the mitral annulus.
Eur Heart J Cardiovasc Imaging. 19: 432, 2018.
142. Sakaguchi T, Totsugawa T, Kuinose M, Tamura K, Hiraoka A, Chikazawa G, Yoshitaka H,. Minimallyinvasive mitral valve repair through right minithoracotomy – 11-year single institute experience. Circ J.
2018; 82: 1705-1711.
143. Sakaguchi T, Kagiyama N, Toki M, Hiraoka A, Hayashida A, Totsugawa T, Tamura K, Chikazawa G,
Yoshitaka H, Yoshida K. Residual mitral regurgitation after repair for posterior leaflet prolapse – importanceof preoperative anterior leaflet tethering. J Am Heart Assoc. 2018 7(11). pii: e008495. doi:
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144. Sakamoto K, Totsugawa T, Hiraoka A, Tamura K, Yoshitaka H, Sakaguchi T: Minimally invasive aortic
valve replacement following root enlargement on too narrow annulus to perform transcatheter aortic valve
implantation. Int Heart J. 2018; 59: 634-636.
145. Totsugawa T, Tsunoda M, Kagiyama N, Otsuki Y, Yoshitaka H, Sakaguchi T: Preoperative simulation
using CT virtual endoscopy for minimally invasive surgery of hypertrophic obstructive cardiomyopathy. Int
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146. Yoshioka D, Toda K, Yokoyama JY, Matsuura R, Miyagawa S, Kainuma S, Sakaguchi T, Sakaki
M, Nishi H, Shirakawa Y, Iwata K, Suhara H, Sakaniwa R, Fukuda H; Osaka Cardiovascular ResearchGroup study group, Sawa Y. Diabetes mellitus adversely affects mortality and recurrence after valve
surgery for infective endocarditis. J Thorac Cardiovasc Surg. 155: 1021-1029, 2018.
147. Matsuura R, Yoshioka D, Toda K, Yokoyama J, Miyagawa S, Yoshikawa Y, Sakaguchi T, Nishi H,
Funatsu T, Yoshitatsu M, Monta O, Fukuda H, Sawa Y; Osaka Cardiovascular Research (OSCAR) Study
Group. Effect of the Initial Strategy for Active Endocarditis Complicated With Acute Heart Failure. Circ J.
2018;82:2896-2904.
148. Totsugawa T, Hiraoka A, Tamura K, Yoshitaka H, Sakaguchi T. Minimally invasive aortic valve
replacement through a right anterolateral mini-thoracotomy for the treatment of octogenarians with aortic
valve stenosis. Heart Vessels. 2019;34(3):462-469.
149. Hiraoka A, Toki M, Hayashida A, Chikazawa G, Yoshida K, Sakaguchi T, Yoshitaka H. Exercise stressechocardiogram for the evaluation of change in the ventricular-arterial interaction after thoracic
endovascular aortic repair. Eur J Cardiothorac Surg. 2019;55:632-638.
150. Une D, Sakaguchi T. Initiation and modification of minimally invasive coronary artery bypass grafting.
Gen Thorac Cardiovasc Surg. 2019 67:349-354.
151. Suzuki K, Yoshioka D, Toda K, Yokoyama JY, Samura T, Miyagawa S, Yoshikawa Y, Hata H, Takano H,
Matsumiya G, Sakaguchi T, Fukuda H; Osaka Cardiovascular Research (OSCAR) Study Group, Sawa Y.
Results of surgical management of infective endocarditis associated with Staphylococcus aureus. Eur J
Cardiothorac Surg. 2019;56:30-37.
152. Hiraoka A, Hayashida A, Totsugawa T, Tamura K, Chikazawa G, Yoshitaka H, Sakaguchi T.
Transprosthetic Cuff Leakage of a Bovine Pericardial Aortic Bioprosthesis. Semin Thorac Cardiovasc Surg.
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153. Muraki R, Totsugawa T, Nagata K, Nakajima K, Oshita T, Arimichi M, Yoshitaka H, Sakaguchi T. Cellsalvage processing of residual cardiopulmonary bypass volume in minimally invasive cardiac surgery. Heart
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154. Kondo N, Totsugawa T, Yoshitaka H, Sakaguchi T. A Case of Coronary Artery Fistula Ligation in
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155. Kondo N, Tamura K, Hiraoka A, Totsugawa T, Chikazawa G, Sakaguchi T, Yoshitaka H. Treatment
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156. Yokoyama J, Yoshioka D, Toda K, Matsuura R, Suzuki K, Samura T, Miyagawa S, Yoshikawa Y,
Takano H, Matsumiya G, Sakaguchi T, Fukuda H, Takahashi T, Izutani H, Funatsu T, Nishi H, Sawa Y.
Surgery-first treatment improves clinical results in infective endocarditis complicated with disseminatedintravascular coagulation†. Eur J Cardiothorac Surg. 2019 Apr 1. pii: ezz068. doi: 10.1093/ejcts/ezz068.
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157. Muraki R, Totsugawa T, Nagata K, Nakajima K, Oshita T, Arimichi M, Yoshitaka H, Sakaguchi T.
Correction to: Cell salvage processing of residual cardiopulmonary bypass volume in minimally invasive
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158. Totsugawa T, Hiraoka A, Tamura K, Yoshitaka H, Sakaguchi T. Ultrasonic annular debridement inminimally invasive aortic valve replacement. Gen Thorac Cardiovasc Surg. 2019 Jun 15. doi:
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159. Sakaguchi T, Totsugawa T, Orihashi K, Kihara K, Tamura K, Hiraoka A, Chikazawa G, Yoshitaka H.
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160. Fukunaga N, Okita Y, Yaku H, Kobayashi J, Uesugi H, Takanashi S, Ito T, Nakao T, Sakaguchi T,
Yamamoto K, Yoshikawa Y, Sawa Y, Koyama T. Hemodynamic Performance and Outcomes of Mosaic
Valve for Aortic Stenosis with Decreased Left Ventricular Function: Results from J-MOVE Study. ASAIO J.
2020;66:532-538.
161. Sakaguchi T, Mizuno T, Ryomoto M, Sekiya N, Totsugawa T, Tamura K, Hiraoka A, Arai H. A new
multi-suction heart positioner for minimally invasive coronary artery bypass grafting. Ann Thorac Surg.
2020;109:e63-e65
162. Kainuma S, Toda K, Miyagawa S, Yoshikawa Y, Hata H, Yoshioka D, Kawamura T, Kawamura A, Ueno
T, Kuratani T, Kondoh H, Masai T, Hiraoka A, Sakaguchi T, Yoshitaka H, Shirakawa Y, Takahashi T, Saito
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163. Sakaguchi T, Totsugawa T, Hayashida A, Ryomoto M, Sekiya N, Tamura K, Hiraoka A, Yoshitaka H.
Stepwise mitral valve repair for Barlow's disease via a minimally invasive approach. J Card Surg. 2020 May
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164. Hiraoka A, Hayashida A, Toki M, Chikazawa G, Yoshitaka H, Yoshida K, Sakaguchi T. Impact of typeand size of annuloplasty prosthesis on hemodynamic status after mitral valve repair for degenerative
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165. Handa K, Yoshioka D, Toda K, Yokoyama JY, Samura T, Suzuki K, Miyagawa S, Matsumiya G,
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166. Sakaguchi T, Totsugawa T, Tamura K, Hiraoka A, Ryomoto M, Sekiya N, Chikazawa G, Yoshitaka H.
Minimally invasive coronary artery bypass grafting: useful routine option for coronary revascularization in
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167. Kondo N, Tamura K, Hiraoka A, Totsugawa T, Chikazawa G, Sakaguchi T, Yoshitaka H. Correction to:Treatment outcomes for acute type A aortic dissection with patent false lumen in patients over the age of 80.
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168. Inoue K, Hiraoka A, Chikazawa G, Totsugawa T, Nakajima K, Masuda M, Yoshitaka H, Sakaguchi T.
Preventive Strategy for Reexpansion Pulmonary Edema After Minimally Invasive Cardiac Surgery. Ann
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169. Tachibana H, Hiraoka A, Saito K, Naito Y, Chikazawa G, Tamura K, Totsugawa T, Yoshitaka H,
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170. Samura T, Yoshioka D, Toda K, Sakaniwa R, Yokoyama J, Suzuki K, Miyagawa S, Yoshikawa Y, Hata
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valve surgery improves clinical results in patients with infective endocarditis complicated with acute cerebral
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171. Hiraoka A, Tachibana H, Yoshitaka H, Sakaguchi T. Giant aneurysm of the right atrial appendage
repaired by minimally invasive approach. J Card Surg. 2019 Nov;34(11):1352-1353. doi:
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172. Totsugawa T, Hiraoka A, Tamura K, Yoshitaka H, Sakaguchi T. Ultrasonic annular debridement inminimally invasive aortic valve replacement. Gen Thorac Cardiovasc Surg. 2020 Jan;68(1):81-83. doi:
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173. Yoshikawa Y, Okada Y, Okita Y, Yaku H, Kobayashi J, Uesugi H, Takanashi S, Ito T, Nakao T, Koyama
T, Sakaguchi T, Yamamoto K, Sawa Y. Long-Term Outcomes of the Mosaic Aortic Porcine Bioprosthesis
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174. Satoh A, Ryomoto M, Sekiya N, Tanaka H, Yamamura M, Yamashita K, Uemura H, Ueda D, Sakaguchi
T. Sutureless aortic valve replacement with concomitant aortic arch reconstruction. J Artif Organs. 2020
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175. Satoh A, Ryomoto M, Sekiya N, Sakaguchi T. An infra-annular malposition of the Perceval suturelessaortic valve. Eur J Cardiothorac Surg. 2020 Sep 19:ezaa272. doi: 10.1093/ejcts/ezaa272. Epub ahead ofprint. PMID: 32949131.
176. Oshita T, Hiraoka A, Nakajima K, Muraki R, Arimichi M, Chikazawa G, Yoshitaka H, Sakaguchi T. A
Better Predictor of Acute Kidney Injury After Cardiac Surgery: The Largest Area Under the Curve Below the
Oxygen Delivery Threshold During Cardiopulmonary Bypass. J Am Heart Assoc. 2020 Aug
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177. Ryomoto M, Sekiya N, Uemura H, Ueda D, Sato A, Yamashita K, Tanaka H, Yamamura M, Sakaguchi
T. Titanium plate to fix crossed rib can cause cardiac tamponade: A cautionary note. Gen Thorac
Cardiovasc Surg. 2020 Jul 25. doi: 10.1007/s11748-020-01449-5. Epub ahead of print. PMID: 32712755.
178. Sakaguchi T. Surgical treatment of heart valve disease: considerations for the dental management(Review) Oral Sci Int 2020;17:126-133.
179. Handa Y, Takahashi K, Sasanuma N, Itani Y, Nagase M, Uchiyama Y, Tamaki A, Sakaguchi T, Domen
K. Predictors of functional decline in activities of daily living at discharge in pateints after cardiovascularsurgery. Circ J. 2020180. Fukunaga N, Okita Y, Yaku H, Kobayashi J, Uesugi H, Takanashi S, Ito T, Nakao T, Sakaguchi T,
Yamamoto K, Yoshikawa Y, Sawa Y and Koyama T. Hemodynamic performance and outcomes of Mosaic
valve for aortic stenosis with decreased left ventricular function: Results from J-MOVE Study. Asaio J.
2020;66:532-538.
181. Satoh A, Yajima S, Sekiya N, Yamazaki S, Uemura H, Ueda D, Tanaka H, Yamamura M, Sakaguchi T.
Inactive large cerebral hemorrhage is not exacerbated by the adjustment of anticoagulation post open-heart
surgery. J Cardiol Cases. 2021 May 13;24(4):186-189. doi: 10.1016/j.jccase.2021.04.003.
182. Yajima S, Satoh A, Sekiya N, Yamazaki S, Uemura H, Tanaka H, Yamamura M, Sakaguchi T. Perceval
sutureless aortic valve replacement after ascending aortic replacement. Clin Case Rep. 2021 Dec
5;9(12):e05126. doi: 10.1002/ccr3.5126.
183. Uemura H, Yajima S, Sekiya N, Yamazaki S, Satoh A, Tanaka H, Yamamura M, Sakaguchi T. Repair ofpacemaker lead-induced right ventricular perforation via a left mini-thoracotomy. J Cardiol Cases. 2021 Jun
16;24(6):307-309. doi:10.1016/j.jccase.2021.05.008.
184. Ryomoto M, Sakaguchi T, Tanaka H, Yamamura M, Sekiya N, Yajima S, Uemura H, Sato A. Surgical
Strategy for Chronic Type B Dissecting Aortic Aneurysm to Prevent Aorta-Related Events. Ann Vasc Surg.
2022 May;82:294-302. doi:10.1016/j.avsg.2021.10.046. Epub 2021 Nov 14.
185. Yoshikawa Y, Okada Y, Okita Y, Yaku H, Kobayashi J, Uesugi H, Takanashi S, Ito T, Nakao T, Koyama
T, Sakaguchi T, Yamamoto K, Sawa Y. Long-Term Outcomes of the Mosaic Mitral Porcine Bioprosthesis inJapan - Results From the Japan Mosaic Valve Long-Term Multicenter Study. Circ J. 2022 Feb
25;86(3):449-457. doi:10.1253/circj.CJ-21-0528.

186. Yamauchi S, Hayashida A, Hirohata A, Sakaguchi T. Intraoperative coronary angiography and fractional
flow reserve measurement with dobutamine infusion in supra-arterial myotomy for a myocardial bridge: acase report. Eur Heart J Case Rep. 2021 Jul 26;5(7):ytab268. doi: 10.1093/ehjcr/ytab268.
187. Kainuma S, Toda K, Miyagawa S, Yoshikawa Y, Hata H, Yoshioka D, Kawamura T, Kawamura A,
Kashiyama N, Ueno T, Kuratani T, Funatsu T, Kondoh H, Masai T, Hiraoka A, Sakaguchi T, Yoshitaka H,
Daimon T, Taniguchi K, Sawa Y; Osaka Cardiovascular Surgery Research (OSCAR) Group. Detrimental
effects of elevated transpulmonary gradient on outcomes following restrictive mitral annuloplasty in patientswith pre-existing pulmonary hypertension. J Thorac Dis. 2021 May;13(5):2746-2757. doi: 10.21037/jtd-202898.
188. Inoue K, Hiraoka A, Chikazawa G, Sakaguchi T. Primary Minimally Invasive Repair with Atriopericardial
Anastomosis Technique for Pulmonary Vein Stenosis after Catheter Ablation. Innovations (Phila). 2021 JulAug;16(4):393-394. doi: 10.1177/15569845211013768.
189. Kainuma S, Toda K, Daimon T, Miyagawa S, Yoshikawa Y, Hata H, Yoshioka D, Kawamura T,
Kawamura A, Kashiyama N, Ueno T, Kuratani T, Funatsu T, Kondoh H, Masai T, Hiraoka A, Sakaguchi T,
Yoshitaka H, Shirakawa Y, Takahashi T, Sakaki M, Taniguchi K, Sawa Y; Osaka Cardiovascular Surgery
Research (OSCAR) Group. Bilateral Internal Thoracic Artery Grafting Improves Survival for Severe Left
Ventricular Dysfunction and Diabetes. Circ J. 2021 Oct 25;85(11):1991-2001. doi:10.1253/circj.CJ-20-0907.
190. Nakae M, Kainuma S, Toda K, Miyagawa S, Yoshikawa Y, Hata H, Yoshioka D, Kawamura T,
Kawamura A, Kashiyama N, Komukai S, Kitamura T, Hirayama A, Ueno T, Kuratani T, Kondoh H, Masai T,
Hiraoka A, Sakaguchi T, Yoshitaka H, Shirakawa Y, Takahashi T, Taniguchi K, Sawa Y; Osaka
Cardiovascular Surgery Research (OSCAR) Group. Incidence, determinants and clinical impact of left
ventricular function recovery after surgical treatments for ischaemic cardiomyopathy. Eur J Cardiothorac
Surg. 2021 Sep 11;60(3):689-696. doi: 10.1093/ejcts/ezab122.
191. Inoue K, Hiraoka A, Sakaguchi T. Additional Discussion From Anesthesiologists: Preventive Strategy
for Reexpansion Pulmonary Edema After Minimally Invasive Cardiac Surgery. Ann Thorac Surg. 2021
Dec;112(6):2111. doi: 10.1016/j.athoracsur.2021.02.065.
192. Honda Y, Takahashi K, Sasanuma N, Itani Y, Nagase M, Uchiyama Y, Tamaki A, Sakaguchi T, Domen
K. Predictors of Functional Decline in Activities of Daily Living at Discharge in Patients After Cardiovascular
Surgery. Circ J. 2021 Jun 25;85(7):1020-1026. doi: 10.1253/circj.CJ-20-0909.
193. Tonai K, Hiraoka A, Hayashida A, Totsugawa T, Chikazawa G, Yoshitaka H, Yoshida K, Sakaguchi T.
Clinical Impact of Flow Adjusted Transmitral Pressure Gradient After Surgical Annuloplasty for Functional
Mitral Regurgitation. Semin Thorac Cardiovasc Surg. 2022 Spring;34(1):54-60.
doi:10.1053/j.semtcvs.2021.02.005. E
194. Kainuma S, Mitsuno M, Toda K, Miyagawa S, Yoshikawa Y, Hata H, Yoshioka D, Kawamura T,
Kawamura A, Kashiyama N, Ueno T, Kuratani T, Kondoh H, Funatsu T, Hiraoka A, Sakaguchi T, Yoshitaka
H, Shirakawa Y, Takahashi T, Sakaki M, Masai T, Saito S, Monta O, Kitamura T, Komukai S, Hirayama A,
Taniguchi K, Miyamoto Y, Sawa Y; Osaka Cardiovascular Surgery Research (OSCAR) Group. Surgical
Ablation Concomitant With Nonmitral Valve Surgery for Persistent Atrial Fibrillation. Ann Thorac Surg. 2021
Dec;112(6):1909-1920. doi: 10.1016/j.athoracsur.2020.11.069.
195. Uemura H, Yajima S, Ryomoto M, Sekiya N, Yamashita K, Tanaka H, Yamamura M, Satoh A, Ueda D,
Sakaguchi T. Off-Pump Resection of an Epicardial Cyst by Using a Minimally Invasive Approach. Ann
Thorac Surg. 2021 Aug;112(2):e119-e121. doi:10.1016/j.athoracsur.2020.11.050.
196. Sakaguchi T, Hiraoka A, Totsugawa T, Hayashida A, Ryomoto M, Sekiya N, Chikazawa G, Yoshitaka H.
Clinical impact of the repair technique for posterior mitral leaflet prolapse: Resect or respect? J Card Surg.
2021 Mar;36(3):971-977. doi: 10.1111/jocs.15312.
197. Sekiya N, Ryomoto M, Tanaka H, Yamamura M, Yamashita K, Yajima S, Uemura H, Satoh A, Ueda D,
Sakaguchi T. Graft Traction Resolved Left Ventricular Outflow Tract Obstruction. Ann Thorac Surg. 2021
Jun;111(6):e415-e417. doi:10.1016/j.athoracsur.2020.09.073.

198. Satoh A, Ryomoto M, Sekiya N, Tanaka H, Yamamura M, Sakaguchi T. Inadvertent subclavian artery
catheter insertion. J Vasc Surg. 2021 Jan;73(1):309-310. doi:10.1016/j.jvs.2020.04.514.
199. Sakaguchi T, Hiraoka A, Ryomoto M, Sekiya N, Tanaka H, Yamamura M. Papillary Muscle
Reorientation for Systolic Anterior Motion After Mitral Valve Repair. Ann Thorac Surg. 2021
Apr;111(4):e305-e307. doi: 10.1016/j.athoracsur.2020.08.065.
200. Ryomoto M, Sakaguchi T, Sekiya N, Uemura H, Yamamura M, Sato A. Surgical strategy for atrial
fibrillation to prevent stroke in patients undergoing cardiac surgery. Gen Thorac Cardiovasc Surg. 2021
May;69(5):790-795. doi:10.1007/s11748-020-01519-8.
201. Uemura H, Ryomoto M, Sekiya N, Tanaka H, Yamamura M, Yamashita K, Satoh A, Ueda D, Sakaguchi
T. Hypo-attenuated leaflet thickening and reduced leaflet motion after the implantation of the Perceval S
sutureless bioprosthesis. J Artif Organs. 2021 Jun;24(2):293-295. doi: 10.1007/s10047-020-01213-9.
202. Wang X, Kanda H, Tsujino T, Kogure Y, Zhu F, Yamamoto S, Sakaguchi T, Noguchi K, Dai Y. Reactive
Oxygen Species Cause Exercise-Induced Angina in a Myocardial Ischaemia-Reperfusion Injury Model. Int J
Mol Sci. 2022 Mar 4;23(5):2820. doi: 10.3390/ijms23052820.
203. Naito Y, Hiraoka A, Himeno M, Chikazawa G, Arimichi M, Yuguchi S, Yoshitaka H, Sakaguchi T.
Clinically optimal neuropsychological tests for postoperative cognitive dysfunction in heart valve surgeries.
Circ J (in press)
204. Hiraoka A, Hayashida A, Totusgawa T, Toki M, Chikazawa G, Yoshitaka H, Sakaguchi T. Flow adjusted
transmitral pressure gradient as a modified indicator of functional mitral stenosis after repair fordegenerative mitral regurgitation. J Card Surg. 2022 Jul;37(7):1827-1834. doi: 10.1111/jocs.16373.
205. Nishiyama M, Inoue Y, Sasaki H, Seike Y, Aoki T, Ueda J, Tsuji A, Ogo T, Matsuda H, Sakaguchi T.
Long-term outcomes of combined pulmonary endarterectomy and additional balloon pulmonary angioplasty
for chronic thromboembolic pulmonary hypertension. Gen Thorac Cardiovasc Surg. 2022 Sep 21. doi:
10.1007/s11748-022-01872-w. Online ahead of print. PMID: 36129607