Ono Pharmaceutical Sustainable Procurement Code for Business Partner

Ono Pharmaceutical Co., Ltd. (hereinafter “Ono Pharmaceutical”) continues to take on thechallenge of providing medicines that truly benefit patients based on the company’s corporate
philosophy of “Dedicated to the Fight against Disease and Pain.”
Our client companies and partner firms who provide services and products to Ono
Pharmaceutical are valuable business partners (hereinafter “Business Partners”) who support
our challenges and business activities.
Ono Pharmaceutical intends to strengthen its management system and initiatives related tosustainability, such as human rights, working environment and the natural environment
together with its Business Partners to enhance the corporate value of Ono Pharmaceuticaland its Business Partners and realize a sustainable society.
In order to achieve this, we have compiled the matters and initiatives that we would like ourBusiness Partners to comply with in areas other than quality into this document, the Ono
Pharmaceutical Sustainable Procurement Code for Business Partner (hereinafter “this Code”).
We promote collaboration with Business Partners who understand compliance with this Codeand the construction of procedures and systems for conducting business activities inaccordance with related laws, regulations, guidelines and industry standards.
This code has been created with reference to the following sustainability-and labor-related
guidelines, standards, etc.

United Nations Global Compact

ISO 26000

https://www.unglobalcompact.org/

https://www.iso.org/iso-26000-social-responsibility.html

Accordingly, after confirming and understanding the purpose and contents of this Code, pleasesubmit the form confirming your consent to this Code and confirm that your clients are alsoaware of it. In addition, we may periodically check the status of initiatives or conduct on-site
audits, in which case we will contact you separately and ask for your cooperation in theseendeavors as well.

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1. Health & Safety
Business Partners shall provide a safe and healthy working environment, including - whereapplicable - for any company-provided living quarters. Health and Safety measures shallextend to contractors and subcontractors on the Business Partner’s sites.
(1) PERMITS & LICENSES REGARDING HEALTH & SAFETY
Business Partners shall comply with related laws of each country and obtain all required healthand safety-related permits, licenses, registration information and restrictions, as well as comply
with their operational and reporting requirements.
(2) WORKER PROTECTION
Business Partners shall protect all employees from chemical, biological and physical hazards,
and physically demanding tasks in the workplace. Business Partners shall also promote
activities for appropriate workplace safety consideration, health management and healthpromotion.
(3) PROCESS SAFETY
Business Partners shall conduct risk assessments and establish programs to prevent orreduce risks, including the management of chemical substances and periodic inspection ofequipment.
(4) EMERGENCY PREPAREDNESS & RESPONSE
Business Partners shall identify and assess emergency situations in the workplace, create
emergency response plans and develop response systems.
(5) HAZARD INFORMATIONBusiness Partners shall comply with laws and standards related to the management ofhazardous chemical substances and the safety of products. In addition, Business Partners
shall educate their employees on hazardous substances, including compounds and compoundintermediates, and create environments where safety information can be obtained from Safety
Data Sheets and other sources.

2. Human Rights & Labor
Business Partners shall protect the human rights of employees and treat them with dignity andrespect.

2 / 7(1) FREELY CHOSEN EMPLOYMENTBusiness Partners shall comply with the human rights-related laws of each country and shallnot use forced, bonded or indentured labor or involuntary prison labor. No employee shall pay
for a job or be denied freedom of movement.
(2) CHILD LABOR & YOUNG WORKERS
Business Partners shall not use child labor. The employment of young workers below the ageof 18 shall only occur in non-hazardous work and when young workers are above a country’s
legal age for employment or the age established for completing compulsory education.
(3) NON-DISCRIMINATIONBusiness Partners shall not discriminate against or treat people unfavorably on the basis ofcharacteristics unrelated to their duties, such as race, nationality, skin color, ethnicity, gender,age, religion, creed, ideology, sexual orientation or gender identity, educational background,disability or illness.
(4) FAIR TREATMENT
Business Partners shall provide a workplace free of harassment, harsh and inhumane
treatment, including any sexual harassment, sexual abuse, corporal punishment, mental or
physical coercion or verbal abuse of employees and no threat of any such treatment.
(5) WAGES, BENEFITS & WORKING HOURS
Business Partners shall explain to employees a breakdown of wages and calculation methods,
and then pay wages that are equal to or higher than the legal minimum wage for each relevant
country and region. Business Partners shall also comply with the laws of each country
concerning holidays and appropriate working hours.
(6) FREEDOM OF ASSOCIATIONBusiness Partners shall recognize the applicable rights of employees to freely form
associations, join labor unions and collectively bargain in accordance with laws in theresolution of workplace- and compensation-related issues.

3. Environment
Business Partners shall manage their businesses in an environmentally responsible andefficient manner to minimize adverse environmental impacts such as climate change. Business

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Partners are also encouraged to conserve natural resources, to avoid the use of hazardous
substances where possible and to engage in activities that reuse and recycle.
(1) PERMITS & LICENSES REGARDING THE ENVIRONMENTBusiness Partners shall comply with the environment-related laws of each country and obtain
all required environmental permits, licenses, registration information and restrictions, as wellas comply with their operational and reporting requirements.
(2) WASTE & EMISSIONSBusiness Partners shall have systems in place to ensure the safe handling, movement, storage,
recycling, reuse or management of waste, air emissions and wastewater discharges. Anywaste, wastewater or emissions with the potential to adversely impact human or environmental
health shall be appropriately managed, controlled and treated prior to release into theenvironment.
(3) SPILLS & RELEASES
Business Partners shall have systems in place to prevent and mitigate the accidental leakage
and release of contaminants, including hazardous substances, into the environment.
(4) BIODIVERSITYBusiness Partners shall promote the use of resources in consideration of biodiversity.
(5) CLIMATE CHANGE
Business Partners shall set targets to reduce greenhouse gas emissions and promote furtherreductions. Business Partners shall also strive to conserve energy and introduce renewableenergy sources.
(6) EFFECTIVE USE OF RESOURCES (RESOURCE SAVING)
Business Partners shall construct programs on resource conservation and the efficient use ofwater resources. In addition, Business Partners shall set targets and take measures for
reducing water consumption.

4. Ethics
Business Partners shall conduct their business ethically and act with integrity.

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(1) COMPLIANCE WITH LAWS
Business Partners shall conduct business activities in compliance with the relevant laws andregulations of each applicable country.
(2) ANTI-BRIBERY & ANTI-CORRUPTION
Business Partners shall create anti-corruption policies and prohibit extortion, embezzlement,bribery (including facilitation payments) and fraudulent accounting, and strive to prevent these
activities from occurring. In addition, Business Partners shall strive to conduct third-party due
diligence to prevent bribery.
(3) FAIR COMPETITION
Business Partners shall conduct their fair business consistent with fair and transparent
competition and in compliance with all applicable competition laws (Act on Prohibition ofPrivate Monopolization and Maintenance of Fair Trade, etc.). Business Partners shall employ
fair business practices including accurate and truthful advertising.
(4) RESPONSE TO ANTISOCIAL FORCES
Business Partners shall eliminate any relationships with anti-social forces and groups thatthreaten the order and safety of a civil society, such as extortionists and crime syndicates, andshall resolutely confront them.
(5) ANIMAL WELFARE
Business Partners shall respect the lives of animals, inflict as little pain as possible on them,and achieve objectives with the minimum number of animals necessary. In addition toconducting animal experiments in compliance with relevant laws, etc., Business Partners shallstrive to verify animal rearing systems and experiment implementation systems throughexternal organizations. Also, alternatives should be used wherever these are scientifically valid
and acceptable to regulators.

5. Information Management
Business Partners shall conduct ethical and honest business activities with respect to the data
they operate.
(1) INFORMATION SECURITY
Business Partners shall comply with each country’s laws, regulations, etc. regarding

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information security, and will take appropriate information security measures to prevent theleakage, falsification, loss, damage, etc. of confidential information handled in businessactivities.
(2) PROTECTION OF PERSONAL INFORMATIONBusiness Partners shall comply with the personal information protection laws of each country,
and shall appropriately manage and protect the privacy of individuals.

6. Management Systems
Business Partners shall operate a management system to promote compliance with therequirements of this Code and strive to continually improve it.
The management system shall contain the following items:(1) COMMITMENT
Business Partners shall demonstrate their commitment to the matters described in this Code.
(2) EDUCATION & TRAINING
Business Partners shall conduct appropriate education and training to ensure that theirmanagement teams and employees can address the expectations in these matters.
(3) CONTINUAL IMPROVEMENTBusiness Partners shall promote continual improvements regarding this Code by setting
performance objectives, executing implementation plans and taking corrective actions toaddress issues identified through audits.
(4) RISK MANAGEMENTBusiness Partners shall recognize the possibility that major risks may occur, strive to prevent
them from happening and establish a system to respond precisely in the event that they dooccur.
(5) REPORTING & CONSULTATION SERVICE
Business Partners shall establish a consultation service with measures in place to prevent
violations of this Code, including harassment, from occurring and/or reoccurring, or to respondquickly and take measures in the event of a violation, such as protecting whistleblowers,prohibiting retaliation, and anonymous reporting.

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(Established on April 1, 2019)(Revised on July 20, 2021)(Revised on November 10, 2022)

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