Anipill brochure®

Innovative solution for reliable, accurate and continuous core temperature monitoring in many species.

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Summary1

Current animal field applications

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Anipill specifications

3About Anipill: To sum up

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Example of research studies®

®

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Current animal field applications
Few examples
ANIMAL PHYSIOLOGY
Thermoregulation
Chronobiology
Sleep research

DISEASES MODEL, INFLAMMATION AND TOXICOLOGY

Virology,
infectiology and Vacine development
VIROLOGY, INFECTIOLOGY AND VACCINE DEVELOPMENT

Virology,infectiology
VacineANIMAL
development
RACINGANIMALand- RESCUE

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Introduction
Anipill®: the essentials

RF 433Mhz
Anilogger
monitorAnipill capsule

Anilogger Manager
softwareActivation box to turn on the pilll
Communication range in real time : from 1 to 3 m (animal size & environment depending)

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About Anipill®

Specifications
Equipement

3 main parameters may impact the performance of the system

From 20g to 40kg, above consult us

Animal specie
Metalic environmentuse of realof
timevs synchronization
Depending on theThecombinationtheseparameters, the number ofmonitorwilltodiffer.
We canadviserequired& help you
define the best configuration for your specific protocol.

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About Anipill : To sum up®

Animal core temperature monitoring
Technical specifications:

Scientific advantages:
NO DATA LOSSNo data loss even if the animal is put out of the communication range for a while.

PILL INTERNAL MEMORY
Embedded memory in the pill allows to continuously store
the last 2000 collected data independently of the life
duration.

REAL TIME & A POSTERIORI DATA RECOVERY

MEASUREMENT PERIODLONG TERM MONITORING

The sampling period can be changed all along theexperiment.

Anipill capsules have a 2-year shelf life and are able to monitor core temperaturefrom 20 days to 10 months depending on the sampling period used.

If the monitor is in the communication range of the pill, you can collect real time data.
If not the monitor will synchronize the missing data as soon as the pill and themonitor are in the same communication range.

SIMPLE WAY OF WORKING
After the capsule activation and implantation (2minprocess), the capsule automatically collects and transmits
accurate and reliable temperature data to the Aniloggermonitor.

Other:TIME SAVER
Save time thanks to quick and easy implementation.

ADD MARKERS

LIGHTWEIGHT & TINYUSED IN SEVERAL ANIMAL SPECIES

Markers can be added all along theexperiment to highlight a specific event.

Capsules are lightweight 1.7g andmeasure 17.7mm x 8.9mm

Designed for animals from 20g to 40kg.
(above consult us)

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Example of research studies
Animal physiology - Thermoregulation
CORE TEMPERATURE CHANGES IN RATS PRE-WARMED TO 40˚C (PW40, N = 17), 1% ABOVEBASELINE TEMPERATURE (PW1%, N = 17) OR WITHOUT WARMING (NW, N = 17).
ANIPILL® ADDED VALUE

1Continuous core temperature control

2

Real time AND a posteriori data recovery

3

Define individual thermoregulatory profile

Publications:
Laperrousaz et al., (2018) Lipoprotein Lipase Expression in Hypothalamus is involved in the Central Regulation of Thermogenesis and theResponse to Cold Exposure
Meyer et al., (2017) Body Temperature Measurements for Metabolic Phenotyping in Mice
Rufiange et al., (2020) Pre-warming before general anesthesia with isoflurane delays the onset of hypothermia in rats

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Example of research studies
Animal physiology - Chronobiology & Sleep research
MEASUREMENTS RETRIEVED FROM ANIPILL® CAPSULES IMPLANTED IP IN NON HUMAN PRIMATESANIPILL® ADDED VALUE

1

Easy access to a long-term core temperaturemonitoring

2

Real time AND a posteriori data recovery

3

Assessment of individual CBT rhythm

Publications:Tattersall et al., (2016) Novel energy-saving strategies to multiple stressors in birds: the ultradian regulation of body temperature
Schulze et al., (2018) Body temperature of bitches in the first week after parturition measured by ingestible loggers
Guisle et al., (2020) Circadian and sleep/wake-dependent variations in tau phosphorylation are driven by temperature

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Example of research studies
Diseases model, Inflammation and toxicology
BODY TEMPERATURE WAS SIGNIFICANTLY HIGHER IN NON-STRESSED (NSC) THAN IN
STRESSED (SF AND SC) ANIMALS. (N = 12/GROUP)
ANIPILL® ADDED VALUE

1Continuous core temperature monitoring

2

Possibility to monitor several animals at the sametime

3

Define individual thermoregulatory profile

Publications:Grusenmeyer et al, (2018), Heat Stress Mitigation Strategies for Boars and Impact of Most Effective on Sperm Parameters
Menneson et al., (2019). Validation of a Psychosocial Chronic Stress Model in the Pig Using a Multidisciplinary Approach at the Gut-Brain andBehavior Levels

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ReachOut to Us
Email addresscontact@animals-monitoring.com

Mailing address
BodyCAP
3 rue du Docteur Laennec
14200 Hérouville Saint-ClairFRANCE

Phone number+33 (2) 61 53 03 29

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