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1st International Conference ofHealth and Longevity Sciences
Yaku-shoku Dogen,‘Medicine and Food, Sharing a Common Origin’
University of Shizuoka

December 18-19, 2008

Lecture Room 13411, University of Shizuoka
52-1 Yada, Suruga-ku, Shizuoka 422-8526, Japan

Workshop:Comprehensive Lectures for Students
13:30-17:40, December 18 (Thursday)

Symposium:
Yaku-shoku Dogen, ‘Medicine and Food, Sharing a Common Origin’
9:00-17:15, December 19 (Friday)

Speakers:
Ronaldo Ferraris (New Jersey Medical School)
Toshinao Goda (University of Shizuoka)
Naohide Kinae (University of Shizuoka)
Hirokazu Kobayashi (University of Shizuoka)
Norihiko Misawa (Kirin Holdings Co., Ltd.; Ishikawa Prefectural University)
Yasushi Ohizumi (Yokohama College of Pharmacy; Tohoku University; University of Shizuoka)
Richard T. Sayre (Donald Danforth Plant Science Center; The Ohio State University)
Takayuki Shibamoto (University of California, Davis)
Barbara Timmermann (University of Kansas)
Keiji Wakabayashi (National Cancer Center Research Institute)
Mitsuhiro Watanabe (Keio University)
Shizuo Yamada (University of Shizuoka)

Global COE Program, University of Shizuoka － Innovation in Human Health Sciences52-1 Yada, Suruga-ku, Shizuoka 422-8526, Japan
TEL: 054-264-5124
E-mail: gcoe@u-shizuoka-ken.ac.jp
URL: http://gcoe.u-shizuoka-ken.ac.jp/

Workshop: Comprehensive Lectures for Students
December 18 (Thursday)
13:30 [Chair: Shizuo Yamada]
Barbara Timmermann (Department of Medicinal Chemistry, College of Pharmacy, University of Kansas):
Functional foods for human health: Ancient knowledge meets modern science
14:30 [Chair: Norio Ohashi]
Takayuki Shibamoto (Department of Environmental Toxicology, College of Agricultural and Environmental
Sciences, University of California, Davis):
Food toxicology: Pesticide residues and fungal toxins
15:30
Break
15:40 [Chair: Hirokazu Kobayashi]
Richard T. Sayre (Donald Danforth Plant Science Center; Department of Plant Cellular and Molecular Biology,
College of Biological Sciences, The Ohio State University):
Crop biofortification: the BioCassava Plus program
16:40 [Chair: Toshinao Goda]
Ronaldo Ferraris (Department of Pharmacology and Physiology, New Jersey Medical School):
The high fructose corn syrup controversy: from biochemistry to epidemiology
18:30
Reception (Dinner with invited speakers): Hotel Associa Shizuoka (Chinese food) (closed)
Symposium: Yaku-shoku Dogen, ‘Medicine and Food, Sharing a Common Origin’
December 19 (Friday)
9:00
Opening address
Masaru Nishigaki (President, University of Shizuoka)
9:05
Introduction to Global COE Program, Yaku-shoku Dogen
Naohide Kinae (Program Leader, Global COE Program; Vice-President, University of Shizuoka)
9:10
Session 1: Functional foods and food-drug interaction [Chair: Shizuo Yamada]
Speakers:
Barbara Timmermann (Department of Medicinal Chemistry, College of Pharmacy, University of Kansas):
Translational investigation of turmeric supplements for the treatment of experimental arthritis: A review oflessons learned (50 min)Yasushi Ohizumi (Yokohama College of Pharmacy; Graduate School of Engineering, Tohoku University;
Graduate School of Pharmaceutical Sciences, University of Shizuoka)
Nobiletin, a citurus flavonoid reverses learning impairment in model animals of Alzherimer’s disease and its
mechanism of actions (20 min)Shizuo Yamada (Global COE Program; Graduate School of Pharmaceutical Sciences, University ofShizuoka)
Is phytotherapy effective for the urinary dysfunction in patients with benign prostatic hypertrophy ? (20 min)
10:40
Break
10:50Session 2: Nutraceuticals: Nutritional basis for drug application [Chair: Toshinao Goda]
Speakers:
Ronaldo Ferraris (Department of Pharmacology and Physiology, New Jersey Medical School)
Developmental regulation of the fructose transporter GLUT5 in the GI tract (35 min)

Toshinao Goda (Global COE Program; Graduate School of Nutritional and Environmental Sciences,
University of Shizuoka)
Gene expression profiles in the peripheral leukocytes as indices of insulin resistance and postprandial
hyperglycemia (20 min)Mitsuhiro Watanabe (Division of Molecular Metabolism and System Medicine, School of Medicine, KeioUniversity)Bile acids signaling pathway for the control of metabolism: Mechanism and its application (30 min)
12:15
Lunch
13:00
Poster viewing
14:00
Session 3: Plant biofortification [Chair: Hiroshi Noguchi]
Speakers:
Richard T. Sayre (Donald Danforth Plant Science Center; Department of Plant Cellular and Molecular Biology,
College of Biological Sciences, The Ohio State University):
Iron biofortification of crop plants, improved strategies (40 min)Hirokazu Kobayashi (Global COE Program; Graduate School of Nutritional and Environmental Sciences,
University of Shizuoka):
Genetic improvement of plants with all plant-derived DNA sequences and its application to polyphenol
enrichment (20 min)Norihiko Misawa (Central Laboratories for Frontier Technology, Kirin Holdings Co., Ltd.; Laboratory of Plant
Gene Technology, Research Institute for Bioresources and Biotechnology, Ishikawa Prefectural University):
Carotenoid biofortification of oil crops, rape and flax plants (20 min)
15:20
Break
15:30
Session 4: Food toxicology and safety [Chair: Naohide Kinae]
Speakers:
Takayuki Shibamoto (Department of Environmental Toxicology, College of Agricultural and Environmental
Sciences, University of California, Davis):
Toxicants formed during processing, complications and heat treatment (40 min)Keiji Wakabayashi (National Cancer Center Research Institute) (40 min)Enhancing effect of hyperlipidemia on colon and pancreatic carcinogenesis and its cancer
chemoprevention (40 min)
Naohide Kinae (Global COE Program; Graduate School of Nutritional and Environmental Sciences, Universityof Shizuoka)
Genotoxic activities of Maillard reaction products and their relationship to diabetic disease (20 min)17:10
Closing remarks
Yasuyuki Imai
17:15
Activities of Global COE Program: Poster presentation and reviewers’ comments
Chair: Naoto Oku
Reviewers: Barbara Timmermann, Yukio Yamori, Masahiro Nishijima, and Toshihiko Osawa
18:40
Buffet: Esta (Shizuoka Prefectural Museum of Art)

Contact:
Administration Office, Global COE Program, University of Shizuoka
52-1 Yada, Suruga-ku, Shizuoka 422-8526, Japan
TEL: 054-264-5124
E-mail: gcoe@u-shizuoka-ken.ac.jp
URL (in Japanese): http://gcoe.u-shizuoka-ken.ac.jp/

Graduate School of Nutritional and Environmental Sciences
http://eng.u-shizuoka-ken.ac.jp/faculties/graduate_life_health/index.html
Graduate School of Pharmaceutical Sciences
http://eng.u-shizuoka-ken.ac.jp/faculties/graduate_pharmacy/index.html
Global COE Program － Innovation in Human Health Sciences
http://eng-gcoe.u-shizuoka-ken.ac.jp/

University of Shizuoka