BUSINESSNEWSHYOGO-KOBE

Comprehensive centers providing one-stop
services to Japanese and foreign companies
wishing to start businesses in Hyogo-Kobe

Hyogo-Kobe Investment Support Center

Hyogo Economic Development Center

Kobe Chamber of Commerce and Industry Building 4F
6-1 Minatojima-Nakamachi, Chuo-ku, Kobe 650-0046
TEL: +81-78-302-2072 FAX: +81-78-302-2265 hkisc@staff.hyogo-iic.ne.jp

March
2011

Vol.

Hyogo-Kobe Business Support Center in Tokyo

10Todofuken Kaikan Building 13F
2-6-3 Hirakawa-chou, Chiyoda-ku, Tokyo 102-0093
TEL: +81-3-3230-2721 FAX: +81-3-3230-2722 hkbsc@hyogo-kobe.jp

HYOGO-KOBE INVESTMENT SUPPORT CENTER

Supercomputer “K” will Meet Research and Development
Needs for the Next Generation in Medical, Energy andVarious Other Fields
Twelve years have passed since the “Kobe Medical Industry Development Project” was launchedwith the aim of developing a medical technology research and development cluster on Kobe Port
Island, in collaboration with related industries participating in the project. Thus far, more than 200
medical-related companies have already established their business institutions on the island (as ofFebruary 2011).
The RIKEN Advanced Institute for Computational Science, located on Kobe Port Island, is scheduled to put its supercomputer - nicknamed “The K” - into full operation in 2012. This computer is
expected to expedite high-tech research and development activities of various research institutions and companies. Typical areas of possible application of this supercomputer include accelerating and streamlining a variety of simulations, upgrading medical treatment techniques and new
medicine development processes, expediting new energy source development, and predicting
climate change.
What is a Supercomputer Used for?
A supercomputer, built to perform a vast number ofcalculations at high speeds, is used for structural analysis, weather prediction and various simulations, basedon results of large-scale numerical analysis in the fields
of molecular dynamics and financial engineering.

and foreign-capitalized companies are also interested
in getting involved in the project. Umicore Japan KK,
a Japanese subsidiary of Umicore, a Belgium-based
global corporation specialized in material technology,
announced in April 2010 that it will invest about fourbillion Japanese yen (nearly 48 million US dollars) tobuild a battery material manufacturing base in Kobe.
This company intends to effectively use the K forvarious purposes, including the research and development of positive-electrode materials for the lithiumion batteries that are essential to electric vehicles.

The K has the World’s Highest Level ofThroughput
The K is currently under construction at a research
institution on Kobe Port Island. Its nickname “K”
stands for the Japanese word “Kei” for 10 ; this supercomputer has a performance of 10 petaflops, aboutfour times faster than the world’ s currently fastest
computer (Tianhe-1A, constructed in China), as ofNovember 2010. The K will go into full-scale operation in 2012 as a facility for common use among companies, universities and other organizations, and is
expected to expedite research and development activities in life science, manufacturing and many othersectors.
16Promoting Wide Use of the K throughCooperation among Industry Academia andGovernment
Technical support is also important for making fulluse of the world’s highest level of supercomputer. From
this standpoint, in April 2011 the Foundation for
Computational Science (FOCUS) will open an institution named “Support Center for Advanced Computational Science and Research” on the first and second
floors of the Computational Science Center Building,located near the supercomputer building. This support
center is equipped with high-security research laboratories and seminar rooms for rent, as well as an industrial entry supercomputer (FOCUS supercomputer)

Many Companies Aiming for Technical
Breakthroughs are Participating in the Project
Many companies have begun to enter Kobe, Hyogo
prefecture, with use of the K in mind. Nonresident
Kobe Gakuin University

whose performance is restricted to a certain level forease of use. Computer specialists will be in the centerat all times, to support computer use. The Universityof Hyogo will open a graduate school (in April 2011)
on the center’ s third to seventh floors. The graduate
school will establish a full-fledged simulation technology research course, the first in Japan, to develop andfoster specialists who can coordinate business-academia
collaboration.
Expected Contribution of the K to Businesses
Supercomputer’ s high analytical performance has been
applied to many products familiar to the public. Typical examples of such application include analyzing thedependence of air flow on the surface configuration ofa golf ball, so as to increase drive distance, or analyzing
the behavior of a weight in the water to enhance thespeed and stability of its sinking performance underthe water. These computer analyses help companies
enhance the competitive edge of their products, interms of both quality and cost. The Hyogo prefectural
government, Kobe municipal government and theFOCUS have jointly been preparing for expanded useof the K supercomputer by companies.

to Sannomiya

Academic Zone

Hyogo University of Health Sciences
Kobe Shukugawa Gakuin University

For Academic Collaboration

Kobe Women’s University

Medical Zone& Junior College
Kobe City General

Convention Facilities

For Advanced Medical Treatment
on Patients’demandHospital

R&D Zone

New Kobe City General
Hospital （2011.7 〜）

Facilities and Support for R&D

RIKEN Center for Developmental
Kobe University Business Incubation Center

Biology (CDB)

Areas of Possible Application
with "K computer"
Life sciences

Drug development, new technologies
for medical treatment and diagnosis

Nanotechnology

Designing new materials, studying
enzyme and catalytic reactions

Manufacturing

Designing safe cars
Faster development of products

Disaster prevention

Predicting seismic waves
Predicting tsunami damage

The environment

Predicting climate change, predicting~ phenomenon
effects of the El Nino

Translational Research Informatics Center (TRI)
Institute of Biomedical Research

Kobe Healthcare Industry Development Center(HI-DEC)& Innovation (IBRI)
Konan University

RIKEN Center for Molecular Imaging Science (CMIS)"K computer"(RIKEN Advanced Institutefor Computational Science)

Kobe University

Aerospace

Designing rocket engines
Aircraft development

Nuclear power

Analyzing whole nuclear power plants
Developing nuclear fusion reactors

Astronomy andastrophysics

Research on the origin of the universe
Studing the formation of planets and galaxies

Kobe Medical Device Development Center(MEDDEC)

Kobe Airp

ort

Kobe Port Island Area
http://www.hyogo-kobe.jp/

BUSINESSNEWSHYOGO-KOBE

Comprehensive centers providing one-stop
services to Japanese and foreign companies
wishing to start businesses in Hyogo-Kobe

Hyogo-Kobe Investment Support Center

Hyogo Economic Development Center

Kobe Chamber of Commerce and Industry Building 4F
6-1 Minatojima-Nakamachi, Chuo-ku, Kobe 650-0046
TEL: +81-78-302-2072 FAX: +81-78-302-2265 hkisc@staff.hyogo-iic.ne.jp

March2011

Hyogo-Kobe Business Support Center in TokyoVol.

10Todofuken Kaikan Building 13F
2-6-3 Hirakawa-chou, Chiyoda-ku, Tokyo 102-0093
TEL: +81-3-3230-2721 FAX: +81-3-3230-2722 hkbsc@hyogo-kobe.jp

HYOGO-KOBE INVESTMENT SUPPORT CENTER

Making Use of Worldwide Networks
for the Pharmaceuticals BusinessLeading the edge of healthcare science with Hyogo-Kobe
Since its 1923 success in making the world’s first commercially available insulin
preparation for diabetes cure, Eli Lilly and Company has developed a host ofepoch-making pharmaceuticals. Based in Sannomiya, Kobe, Eli Lilly Japan is thesecond largest operation after the company’s U.S. head office, and plays animportant role in the company’s global network of operations in over 140 countries. Eli Lilly Japan delivers pharmaceutical products in such areas as neuroscience, diabetes, growth hormones, musculoskeletal disorders and cancer. The
company’s sales in FY 2010 are projected to reach 130 billion yen. The following
are excerpts from the lecture given by Mr. Alfonso G. Zulueta, President andGeneral Manager of Eli Lilly Japan, at JETRO Headquarters Tokyo in September
2010.
Mr. Alfonso G. Zulueta, President and General Manager, Eli Lilly Japan K.K.

“Research is at the very heart of theenterprise”
This is the ideal handed down since the founding ofEli Lilly and Company. For its 130-plus years ofhistory, true to its mission of “making medicines that
help people live longer, healthier and more activelives,” Eli Lilly has devoted itself to developing epochmaking medicines through in-house innovation andhas continued to grow through ceaseless pursuit of its
founding corporate values, i.e., integrity, excellence,and respect for people. As solutions to various difficult
diseases, we have developed and provided numerous
pharmaceuticals that are the “first of their kind in theworld.” At present, we operate research and development facilities in eight countries in the world, including Japan.
Doing business from Kobe City, Hyogo
Prefecture
The first advantage Kobe offers is its efficient, costeffective location for business activities. We actually
made numerous comparisons to Tokyo and consistently found distinct cost advantages for locating inKobe, in light of overall operating expenses. We havean office in Tokyo, as well. Thanks to the airports, theShinkansen and other transportation infrastructures,
however, we have never felt that traveling between thetwo cities was a burden.
Secondly, Kobe, not being as big a city as Tokyo, gives
us a bigger presence in the community, allowing us toattract excellent talents. My family and I live on
Rokko Island, a pretty community surrounded by seaand mountains, whose residents enjoy quality living.
There are also plentiful educational institutions such as
Canadian Academy, making it a comfortable place toraise children and an attractive source of global talents.
At the Boston Career Forum I attend every year, it isamazing how many Japanese talents working in theU.S. and Europe want to work from the Kansai area.

Our U.S. head office is building a global partnershipin drug discovery, using a virtual development process
called “Chorus” and an assay system called “PDSquare.” In the same way, we at Eli Lilly Japan believe
it is possible to expand our value chain to the full, sothat it will encompass various activities, from research& development to manufacturing to sales.

drugs and obtaining approval for additional indications for our existing products. As a result, our annualsales exceeded 100 billion yen for the first time. In theyears to come, we are determined to continue doing
our utmost to deliver first-in-class, best-in-class, breakthrough medicines in such focus areas as depression
and diabetes.

CSR activities such as community andpatient support programs
For people living with disease, revolutionary medicines
are not enough. Information relating to diseases andcures, courage to face illnesses, and support andencouragement from people around are also part of thesolution to illnesses.
Our programs, such as “Lilly Oncology on Canvas”
and “Support for Independent Lives of Persons with
Mental Disabilities (Lilly Award),” emerged as a resultof listening to the voices of patients and families livingwith illnesses. Also, we strongly support the Walk-AThon in Kansai, a charity walk event started in 2006
and sponsored jointly by the Kansai Chapter of theAmerican Chamber of Commerce, Japan (ACCJ),
which I serve as governor, and local governments.
Many Lilly staff participate in the event as members ofACCJ. This kind of support from Hyogo Prefecture
and Kobe City is another great advantage of being
based here.
Contribution to Japan’s medical and healthcare
We believe that diabetes and other endocrine andmetabolic disorders, as well as osteoporosis, cancer andcentral nervous system disorders are the important
areas where Elli Lilly can establish itself even more
firmly in Japanese society and contribute further toJapan’s medical and health care.
In FY 2009, despite the difficult environment
surrounding the pharmaceutical industry, we were
fortunate to make good progress in introducing new

http://www.hyogo-kobe.jp/

Eli Lilly Japan K.K.
Location: Sannomiya Plaza Bldg., 7-1-5 Isogami-dori,Chuo-ku, Kobe
Founded: November 1975
Capital: 12,772,500,000 yen
Business: Manufacture and sales of pharmaceuticalproducts
No. of employees: 2,300 (as of October 2010)
No. of offices in Japan: 8 (plus 15 sales centers)
Manufacturing site: Seishin Laboratories, 4-3-3 Takatsukadai, Nishi-ku, Kobe