GPS Safety Summary Reference No. : JIPS_MSP_CE-JP101_EN

GPS/JIPS Safety Summary
1. PRODUCT NAME
Alumina (aluminum oxide) (CAS No.: 1344-28-1)

2. GENERAL STATEMENT
Alumina is a white-colored, powdery crystalline formed through the calcination of aluminumhydroxide. Numerous crystalline forms of alumina are known of, but the most stable and widelyused is alpha alumina. Alpha alumina has a high melting point, is thermally stable, has a hardness
next to that of diamond, is high in electric insulation and resistance properties, and remains stablein the presence of acids and alkalis.

3. CHEMICAL IDENTITY
Item
Chemical orname
Trade name
CAS No.
Other Nos.

Description
generic Aluminum oxide

Chemical Formula
Source/References

Alumina (aluminum oxide)1344-28-1
Japan: Chemical Substances Control Law (1)-23
Japan: Industrial Safety and Health Act, existing chemical substance
Al2O3
Section 3 of the SDS issued by Resonac Corporation

4. USES AND APPLICATIONS
Main uses

Our product has mainly been used with fire-proof materials, insulators,
spark plugs, IC substrates and packages, drilling and polishing materials,
and in ceramics for heat and chemical resistant products, etc.

5. PHYSICAL/CHEMICAL PROPERTIESThe substance is a white-colored odorless powder that hardly dissolves in water.
Appearance
ColorOdor
Melting point/Boilingpoint
Flammability
Relative density
Solubility
Explosive properties
Oxidizing proparties
Sources/references

PowderWhite
Odorless2053 ℃／3000 ℃
Non flammable
3.98g/cm3(20℃)
Water: Insoluble, Acid: Insoluble, Alkali: Very slightly soluble. Othersolvents: no data available
Not explosive
Not oxidizing
Section 9 and 10 of the SDS issued by Resonac Corporation

6. HEALTH EFFECTS
Effect assessment

Results （GHS Hazard Classification）
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GPS Safety Summary Reference No. : JIPS_MSP_CE-JP101_EN

Acute toxicity (oral)
Acute toxicity (dermal)
Acute toxicity (inhalation: gas)
Acute toxicity (inhalation: vapours)
Acute toxicity (inhalation: dust, mist)
Skin corrosion/irritation
Serious eye damage/eye irritation,
Respiratory sensitisation

Not classified
Classification not possible
Not applicable
Classification not possible
Classification not possible
Not classified
Not classified
Classification not possible

Skin sensitisation
Germ cell mutagenicity
Carcinogenicity
Reproductive toxicity
Specific target organ toxicity — Single exposure,Specific target organ toxicity (repeatedexposure)Classification not possible

Aspiration hazard
Sources/references

Classification not possible
Classification not possible
Classification not possible
Category 3 May cause respiratory irritation
Category 1 Causes damage to organs (lungs)
through prolonged or repeated exposure(Inhalation).
Classification not possible
Section 2 and 11 of SDS issued by Resonac
Corporation• GHS (Globally Harmonized System of Classification and Labelling of Chemicals): A system that classifies chemicals
according to the type and degree of hazards, labels the information, and provides safety data sheets according to
globally harmonized rules.
• Not applicable: Since the priority of physical state, chemical structure, chemical property, and hazard items used in
the GHS classification procedures does not fall under the category, it is not subject to the classification for thecategory.
• Not classified: Sufficient information has been obtained to implement the GHS classification, and as a result of theclassification, it does not fall under any of the hazard categories specified in the GHS. • Classification not possible :There is not enough information for GHS classification, and classification is not possible.

7. ENVIRONMENTAL EFFECTS
Effect assessment
Hazardous to the aquatic environment, shortterm (acute)Hazardous to the aquatic environment, longterm (chronic)
Hazardous to the ozone layer
Sources/references
Environmental fate/dynamics
Mobility in soil
Persistence/degradability
Bioaccumulation potential
Conclusion about
PBT/vPvB

Sources/references

Results （GHS Hazard Classification）
Not classified
Classification not possible
Classification not possible
Sections 2 and 12 of the SDS issued byResonac Corporation

No additional information available.
No additional information available.
No additional information available.
The criteria for persistent bioaccumulative and toxic (PBT;remaining persistently in the environment and possessing highbioaccumulation potential and toxicity) and very persistent andvery bioaccumulative (vPvB; remaining very persistently in theenvironment and possessing very high bioaccumulation potential)
chemicals are believed to inapplicable.
Sections 12 of the SDS issued by Resonac Corporation

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GPS Safety Summary Reference No. : JIPS_MSP_CE-JP101_EN

8. EXPOSURE
DetalsOccupational exposures

Consumer exposures

Environmental exposures

Precautions

Exposure potentials through main uses
When handling powders of the substance under normal
temperatures, workers could be exposed through oral ingestion,
contact with the skin, or inhalation if dust is generated during
mixing/blending, measuring, packing, unpacking and otherprocesses involving the substance. Harmful effects have beenrecognized mainly when the substance's high-density dust wasinhaled. This may cause coughing and shortness of breath.
Additionally, the substance could cause irritation in direct contact
with the respiratory tracts, eyes and skin. However, the harmful
effects resulting from oral intake of the substance are believed tobe minor.
The substance is used as a source material for heat and chemical
resistant ceramics and other products, so there is the potentialthat consumers could be exposed through dermal of inhalation.
Harmful effects have been recognized mainly when its highdensity dusts were inhaled, and this could cause coughing andshortness of breath. The substance could also irritate respiratory
tracts, as well as the eyes and skin upon direct contact. The
harmful effects resulting from oral ingestion are believed to beminor.
Although environmental exposure is possible in the following cases,no specific effects on the environment have been reported, as
mentioned in Section 7 Environmental Effects.
If there is a possibility of exposure in other uses, take appropriate
measures with reference to recommended risk management
measures.

9. RISK MANAGEMENT RECOMMENDATIONS
Recommended risk management measures can minimize risks to workers, consumers, and theenvironment from Section 8 exposure scenarios.
DetalsWorkerRisk management recommendations
Technical measures:
Carry out exhaust ventilation in order to keep a concentration of
the substance in the air below the exposure limit value. Install
eyewash fountains and safety showers at manufacturing places
where the product is stored or handled.
Local and general ventilation:
For controlling and restricting environmental concentrations below
the following recommended values, install local exhaust or total
ventilation systems at places where the product is manufactured
or handled.
Acceptable concentration:
With regard to the product, the Japan Society for Occupational
Health published (in 2011) the recommendation values as
occupational exposure limits of 0.5 mg/m3 for respirable dust
(class 1 dusts) and 2 mg/m3 for total dust (class 1 dusts), while
the American Conference of Governmental Industrial Hygienists
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GPS Safety Summary Reference No. : JIPS_MSP_CE-JP101_EN(ACGIH) published the threshold limit value of 1 mg/m3 (timeweighted average; TLV-TWA). Implement management and control
measures to keep its dust concentration below these values.

Consumer

Environment

Precautions

Protective equipment:
While working, wear appropriate protective eyewears, dust-proof
masks, air-supplied respirators, clothes and protective gloves madeof materials impermeable to powders.
Precautions:
The operation manager should educate operators about theselection of appropriate protective equipment, proper usage
method, and control method of the work site.
If dusts have been generated, take a precaution not to inhale its
dusts and not to directly contact with its dusts on the humanbody. If the exposure amount is large, implement risk management
measures similar to those indicated in “Occupational Exposures”
above.
In order to prevent environmental exposures, implement
preventive measures against leakage into rivers, water channels,and sewerage trenches, and pay attention to the daily
management and handling of the substance.
For normal handling, emergency response, disposal, andtransportation control measures, refer to sections 4, 5, 6, 7, 8, 13,
and 14 of the SDS issued by Resonac Corporation.

10. STATE AGENCY REVIEW
Hazard assessment
International Chemical
Safety Cards

Situations of review
International Chemical Safety Card
https://www.ilo.org/dyn/icsc/showcard.display?p_lang=en&p_card_id=0351

OECD HPVHigh production volume chemical testing programme
https://hpvchemicals.oecd.org/ui/search.aspx

NITE-CHRIP（NITE ChemicalRisk Information Platform）
GHS Classification Resultsby the Japanese
Government

https://www.nite.go.jp/en/chem/chrip/chrip_search/srhInput
https://www.nite.go.jp/chem/english/ghs/06-imcg-0730e.html

11. REGULATORY INFORMATION／GHS CLASSIFICATION AND LABELLING INFORMATION
Regulatory information only in Japan
Applicable laws
Regulatory situations
Industrial Safety andHealth Act

Dangerous or Harmful Substances Subject to Be Indicated theirNames（Article 57 Paragraph (1) of the Act, Article 18 item(ⅰ)
and item(ⅱ) appended Table No. 9 of the Enforcement Order）
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GPS Safety Summary Reference No. : JIPS_MSP_CE-JP101_EN

Dangerous Articles and Harmful Substances Whose Names, etc.
Should Be Notified（Article 57-2 of the Act, Article 18-2 item(ⅰ)
and item(ⅱ) appended Table No. 9 of the Enforcement Order）
Aluminum oxide（Cabinet Order Number : 189）
Poisonous and Deleterious
Substances Control Act

Not applicable

Water Pollution Prevention
Act

Designated substances（Article 2, Paragraph 4 of the Acr, Article
3-3 of the Enforcement Order）
aluminum and aluminum compounds

Foreign Exchange andForeign Trade Act

Paragraph 16 of Appended Table 1 of the Cabinet Order on
Export Trade Control

Water Supply Act

Hazardous Substances (Article 4, Paragraph 2 of the Act), Water
Quality Standards (Ordinance of the Ministry of Health, Labour andWelfare No. 101 of 2003)
Aluminum and aluminum compounds
Not applicable

Act on the Assessment ofReleases of Specified
Chemical Substances in theEnvironment and thePromotion of Management
Improvement and Transfer
Register / PRTR)
Pneumoconiosis Law

UN classification
azardsHealth hazards

Article 2 of the Act, Article 2 of the Enforcement Ordinance,
Appended Table Dusty work
alumina
Not applicable
Classification results (hazard information)
Specific target organ toxicity — Single exposure Category 3（Respiratory tract irritation）
Specific target organ toxicity (repeated exposure) Category 1（lung）

Labelling Information
Hazard pictograms (GHS)

Signal word (GHS)
Hazard statements (GHS)

DangerMay cause respiratory irritation (H335)
Causes damage to organs (lungs) through prolonged or repeatedexposure (Inhalation). (H372)

12. CONTACT INFORMATION
CompanyAddress
Departments
Tel. / Fax

Resonac Corporation
13-9, Shiba Daimon 1-Chome, Minato-ku, Tokyo 105-8518
JapanCeramics Business Unit Marketing Department+81-3-5470-3434／rec_cera.div@resonac.com

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GPS Safety Summary Reference No. : JIPS_MSP_CE-JP101_EN

13. DATE OF ISSUE / REVISION, ADDITIONAL INFORMATION
Date of issue: November 28, 2013
Revisions:
Date of revision
Revised section
Revised item
January 1, 2023
3, 6, 11, 13
update to the latest information
The contents are based on the safety data sheet (SDS) revised on January 1, 2023.

VersionRev.2

Special instructions: none

14. DISCLAIMER
The safety summary is part of the effort for the voluntary management of chemical substance inthe chemical industry (GPS/JIPS: Japan Initiative of Product Stewardship). The purpose of thesafety summary is to provide information on the safe handling of the product as an overview andnot to provide professional information, such as the risk evaluation process and its impact onhuman health and the environment. This document is not meant to serve as an alternative to risk
evaluation, such as a Safety Data Sheet (SDS) or a Chemical Safety Report (CSR). This safetysummary is being written as accurately as possible based on data such as laws, materials, andinformation available at the time of publication, but it does not include all data. It does notguarantee anything.

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