Kao Corporation
GLOBAL PRODUCT STRATEGY SAFETY SUMMARY
POIZ 521
This document is a high-level summary intended to provide the general public with anoverview of product safety for this substance. It is not intended to replace the Safety Data
Sheet, which is available from suppliers and should be referred to for full details ofrecommended safety procedures for each type of use. It is not intended to replace orsupersede manufacturer’s instructions and warnings for their consumer products containing
this substance.

1. Substance Identity
Brand Name: POIZ 521
Chemical Name: Acrylic acid/maleic anhydride copolymer sodium salt
CAS Number: 52255-49-9

2. Uses and Applications
POIZ 521 is a polycarboxyric acid type surfactant.
For the industrial use, POIZ 521 is mainly used as a dispersant for paint, ceramics, adhesive,etc.
POIZ 521 is not sold to consumers and is limited to industrial use only.

3. Physical/Chemical Properties
POIZ 521 has no identified physicochemical hazards.
Property

Value

Physical state

Viscous liquid

ColourPale yellowOdour

Almost odourless

pHDensity
Melting point (Pour point)

8.2 (Undiluted)
1.325 g/mL (20 °C) (68 °F)-15 °C (5 °F)

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Boiling point
Flash point
Flammability or Explosive properties

102-103 °C (215.6 - 217.4°F)
Not applicable
No information available

Explosive properties

No information available

Self – ignition temperature

No information available

Vapour pressure

No information available

Water solubilitySoluble

Octanol-water partition coefficient (log Kow)

No information available

Viscosity

125 mPa･s (25 °C) ( 77 °F)

4. Human Health Safety Assessment
The Short-term and repeated exposure of POIZ 521 does not cause any toxic effects
Effect Assessment

ResultNo acute toxicity after oral/ dermal exposure.
The substance does not cause damage toany organs following single exposure
Based on the available data, unlikely tocause skin irritation and eye irritation
Based on the available data, unlikely tocause allergic skin reaction
Unlikely to cause any toxic effects throughprolonged or repeated oral exposure inpractical use
Based on the available data, unlikely tocause genetic defects
Based on the available data, unlikely tocause cancer
Based on the available data, unlikely to bedamaging to fertility or the unborn child

Acute Toxicity
oral/ dermal
Irritationskin/ eyeSensitization
Toxicity after repeated exposure
Mutagenicity
Carcinogenicity
Toxicity for reproduction

5. Environmental Safety Assessment
The test results with fish, aquatic invertebrates and algae suggest that POIZ 521 is not tocause toxicity for aquatic organism. From the information of general polymer, it seems to be
not readily biodegradable, but it is considered to be removed by sewage treatment etc. It is
not bioaccumulative because of high molecular weight of polymer.
Effect Assessment

ResultAquatic Toxicity

Suggests not to cause toxicity for aquatic organism.

Biodegradation

It seems to be not readily biodegradable.

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Effect Assessment

Result

PBT/ vPvB conclusion*

Not considered to be either PBT nor vPvB.

*PBT=Persistent, Bioaccumulative and ToxicvPvB=Very Persistent and Very Bioaccumulative

6. Exposure
Consumer
POIZ 521 is used as a dispersant for paint, ceramics, adhesive, etc. POIZ 521 is hardly
eluted from these industrial products, so it is considered that exposure to consumers hardlyoccurs.
WorkerThe exposure can occur either in POIZ 521 manufacturing facilities or in the various
industrial facilities when POIZ 521 is used. Those workers in industrial operations during
maintenance, sampling, testing, or other procedures could be exposed with POIZ 521. Only
qualified and trained workers handle the undiluted substance. The manufacturing facilities
offer thorough training program for employees and appropriate work processes, as well as
safety equipment (goggles and gloves) in place to present an unnecessary exposure. Safety
showers and eye-wash stations are accessible nearby. Workers are required to be trained inaccordance with the safety measures in the Safety Data Sheet.
Environment
POIZ 521 is discharged to wastewater treatment plants from industrial sites such as
manufacturing, preparation, handling, storage. However, this material is considered to beefficiently removed at the wastewater treatment plants. Even if it remains slightly in thewastewater, it is considered not toxic to aquatic organisms. Furthermore, this substancedose not accumulate in the food chain, so that there is no concern of human exposure
through environmental pathway.

7. Risk management recommendations
When you use the substance, make sure to be measured the adequate ventilation. Always
use appropriate chemical-resistant gloves to protect your hands and skin and always wear
eye protection equipment. Do not eat, drink or smoke where the substance is handled,processed or stored. Wash hands and skin after contact with the substance. When thesubstance attaches to skin (or hair), take off the contaminated clothes. Wash with a large
amount of water and soap. If the substance gets into your eyes, rinse your eyes thoroughly
for several minutes. If you wear contact lens, and you can take it off easily, take it off andcontinue to rinse your eyes. When it causes your skin irritation or eye irritation, consult
doctor (medical diagnosis/therapy).
Waste water containing the substance must be passed the waste water treatment plants inorder to remove the substance. No specific measures are needed, because it is notexpected to be released into the air.
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8. Regulatory Information / Classification and Labelling
Under GHS classification chemical substances are classified in hazards for physicalproperties, human health and environment. The hazard information for industrial products
are transmitted via specific labels and Safety Data Sheet. GHS offers the standardization for
hazard communication. The subjects who could be assumed to be exposed to the substance,workers, consumers, transport workers, and emergency responders, can better understandthe hazards of the chemicals in use through the transmission.

Labeling according to UN GHS

UN GHS is the basis for country specific GHS labeling.

Classification and Labeling Information
POIZ 521 is not classified as a substance that has a harmful effect on humans or theenvironment.
The laws of manufacturing, sale, transport, use and disposal are different among countries
or areas. Details are referred to Safety Data Sheet provided by the supplier.

9. Conclusion
POIZ 521 is thought to be not readily biodegradable, but environmental risks are notconsidered to be a concern because it is efficiently removed at wastewater treatment plants
and does not exhibit toxicity to aquatic organisms. Although POIZ 521 is not considered toexhibit toxicity due to short-term and repeated exposure, workers need to refer to Safety
Data Sheet according to standard safety measures. Consumers are not considered to havea risk in use.
10. Contact information within company
For further information on this substance or product safety summaries in general, pleasecontact:Name

Kao Corporation, Global Chemical Business

Telephone number+81-3-5630-7700

Fax number+81-3-5630-7889

E-mail address

chemical@kao.co.jp

Additional information can be found at a chemical risk assessment support portal provided
by the Japan Chemical Industry Associations, found at https://www.jcia-bigdr.jp/jciabigdr/en/top.

11. GlossaryHazard
4 of 5

Hazardous property for human health or environments
Global Product Strategy Safety Summary – POIZ 521

Acute Toxicity

Globally Harmonized System of Classification and Labelingof Chemicals
Adverse effects that result from a single exposure

Sensitization

Inducibility of allergy

Mutagenicity
Toxicity after repeatedexposureEffects to induce gene mutations

GHS

Adverse effects that result from repeated exposure

Carcinogenicity

Adverse effects for teratogenicity, embryotoxicity, andreproductivity
Action influence to cause a cancerBiodegradation

Biological degradation of a substance in environments

Bioaccumulation

Accumulation of substances in environments

Toxicity for reproduction

12. Date of issue
December 20 2019

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