FY2024 Open Call Guidelines for Joint Research, Research Seeds
Research Center for Global and Local Infectious Diseases, Oita University

The Research Center for GLOBAL and LOCAL Infectious Diseases (RCGLID) wasestablished by Oita University on 1st October 2021 as a national joint-use facility tostrategically promote the strengthening of university-wide research capabilities in infectious
diseases. It also contributes to the enhancement and improvement of the research
infrastructure for infectious diseases in Japan.
In collaboration with domestic and international research institutes, RCGLID links a seriesof areas from basic research to clinical practice, including analysis of the pathophysiology of
infections caused by microorganisms, genome analysis, microbiome research, and drug
discovery, which is one of the strengths of our university. By seamlessly collaborating, we
aim to build an international and regional core research platform for infectious diseases. We
are now inviting applications for joint research projects as outlined below.

1. Outline for Call
(1) Call for Proposals
We will accept applications in two categories: A) Joint Research and B) Research Seeds.
The applicant (Principal Investigator), in cooperation with the faculty member in charge of theCenter, will conduct joint research by setting up a research proposal in accordance with thetheme.
A) Joint Research(Maximum application amount: 1,000,000 yen/proposal, FY 2024)
Research themes of this center are listed on pages 5 to 11 of this guideline which will be
carried out in cooperation with the center's faculty. In particular, we will focus our support
on research areas that are of international and academic importance and are strategically
implemented by this center.
Research period: Up to 3 years (continued application is required at the time of eachannual open call)B) Research Seeds(Maximum application amount: 300,000 yen/proposal, FY 2024)
In this category, we call for proposals in which the applicant conducts research on infectious
diseases based on new ideas in collaboration with the Center's faculty members, with the
expectation of expanding the scope of research and promoting collaborative research.
Applicants should consult with the Center's faculty members to determine their research
topics and apply.
Research Period：Up to 2 years*1 For continuing proposal, please use the same Research Topic as the previous fiscal year.
*2 The expenses for FY2024 should be completed by the end of February 2025.
(2)Application Requirements
The applicant must be a researcher of a research institution, such as a faculty member of
any university, or a researcher who is recognized by the director as having research ability
equivalent to that of a faculty member.
We welcome applications from researchers, including young researchers, female
researchers, and foreign researchers within the research organization, especially as Principal
Investigators.

-1-Graduate students are not eligible to apply. However, graduate students may be included
as a member of the research team.
(3) Research Period
You can indicate a research plan for multiple years ( A)Joint Research: up to 3 years,B)Research Seeds: up to 2 years. ). However, the budget execution period is within FY2025.
Please submit Application Form every year because the selection review will be conductedannually.
(4) Determination of the amount available and allocated for each application
A) Joint Research maximum 1,000,000JPY/FY
The Center will review the allocated amount and determine the adopted amount.

Additions to the amount allocated
If the Principal Investigator of each proposal meets the following requirements, an additionalamount of up to 300,000 JPY per proposal may be allocated.
* If you belong to an overseas institution*If you are 39 years old or younger as of April 1, 2024.
* For female researchers※Please do not include the additional amount in "12 Required Expenses" in the application
form for the joint research proposal.
B) Research Seeds maximum 300,000JPY/FY*The Center will determine the amount to be allocated based on the status of applications
and screening results.
The expenses that can be applied for "travel expenses" and "research expenses".
Funds will not be allocated directly to the Principal Investigators, and all accounting will behandled by the Center.
2. How to Apply(1) Application

Form 1: Application for Joint Research / Research Seeds Fiscal Year 2024
Form 2: Report for Joint Research Fiscal Year 2023 (*)※ In the case of a continuation of an application from or before FY 2023 or a new application
for FY 2024 after the completion of a proposal for FY 2023, please prepare and submit areport on the results of Form 2 at the time of application. The final version should be submitted
at the end of the fiscal year (submission deadline is April 30, 2024).

The Principal Investigator should submit the application (Form 1) after conducting asufficient discussion with the corresponding faculty member of the Center in advance, by email, or by other means. Also, starting from this year, we have added a column for commentsof RCGLID faculty members. So, please ask the faculty members in charge of this center toenter comments regarding this joint research.
For submission, please send a converted PDF file as an attachment by e-mail to thefollowing contact person. Please keep your application no longer than four (4) pages.

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【Contact person】
Research Center for Global and Local Infectious Diseases, Oita University
E-mail: glocal@oita-u.ac.jp
Tel: +81-97-586-5444
Homepage: https://www.oita-glocal.jp/en/index.html(2) Deadline for application
5:00 p.m. , February 7, 2024 (Wednesday) （JST）(3) Acceptance or Rejection
Applicants will be notified of the outcome by the beginning of April 2024. In the review
process, the adopted amount will be determined based on the number of applicants, thecontents of the proposal, the previous year’s report (if it is a continuation of a proposal),and the appropriate amount for the project.
Therefore, the adopted amount may be reduced than the application amount.
In addition, proposals with extremely low review scores will be rejected.
Name and affiliation of the principal investigator, the title of the research project, andthe results of the research will be made public on the Center's website and in its annual
report, etc., for the adopted research projects.

(Reference) Review perspective(1) Academic importance and validity of the research topic.
(2) Validity of research plan and methods.
(3) Originality and innovation of the research topic.
(4) Utilization of the Center.
(5) Contribution to the region and the world.
(6) Validity of the use expenses.
3. Responsibilities of the Principal Investigator after Adoption(1) Report of Research Results
The Principal Investigator is required to submit the "Report on Joint Research Results"
within 30 days after the end of the research period of each fiscal year. The results of this joint
research may be presented at a result reporting meeting for evaluation purposes.
(2) Publication of results
In principle, the results of this joint research must be published in an academic paper orpresented at an academic conference (with proceedings) collaborated with a faculty memberof the Center. Please be sure to indicate in the Acknowledgments section that these are theresults of the conducted joint research.
【English】
Example 1. This work was (partly) conducted by the joint research program of the ResearchCenter for GLOBAL and LOCAL Infectious Diseases、 Oita University (#####)
Example 2. This work was (partly) supported by the Research Center for GLOBAL and
LOCAL Infectious Diseases、 Oita University(#####)“#” means the adoption number-3-

Please inform us of your results by e-mail, and submit one copy of the reprint (PDF is
acceptable) or one copy of the poster to us: glocal@oita-u.ac.jp
We may contact you regarding follow-up surveys on the research results after the joint
research period.
The submitted reports and papers will be reported in the Center's activity reports, annual
reports, the Center’s website, etc. In addition, we plan to publicize outstanding researchfindings in mass media. When publicizing with the mass media, we will make adjustments
after we have inquired in advance whether or not the information can be disclosed.
(3) Issues Relevant to the Protection of Human Right and Compliance with Laws
and Regulations
If the proposed research involves such issues that require obtaining the consent and/or
cooperation of third parties, consideration in handling of personal information, or actions
related to bioethics and/or biosafety, including the laws, regulations, and guidelines in the
country/region(s) where the joint international research is to be conducted, describe themeasures and actions planned to be taken in responding to these issues in (Form1 ）Application for Joint Research ＆Research seeds FY2024 [section 8. Issues Relevant to theProtection of Human Right and Compliance with Laws and Regulations].
This provision applies to research activities that would require approval by an internal orexternal ethical jury, such as research involving the handling of personal information fromquestionnaire surveys, interviews and/or behavior surveys, including personal histories andimages, handling of donated specimens, human genome analysis, recombinant DNA, andexperimentation with animals.
(4) Handling of Intellectual Property Rights
If any intellectual property has been created through this Joint Research, please contact theCenter's Faculty and Research Collaborators before filing an application, etc., and also
contact the department in charge of intellectual property at the organization to which you
belong. The share of rights, application procedures, etc. will be determined throughdiscussion.
4. Other(1) Disclosure of Information
In the case that information disclosure is requested by an external party, the accepted
application form may be disclosed except for the information that can be personally identified.
In the course of conducting research, please mark any part that you do not want to bedisclosed (such as descriptions including originality) with an underline in the application form.
It will be considered at the time of disclosure.
(2) Personal Information, etc.
We will strive to protect personal information obtained in relation to this recruitment inaccordance with the personal information protection policy of the Oita University.
These guidelines are subject to the approval of the 2024 budget, Oita University.
Therefore, please note that there is a possibility that the contents and the adopted
amount may change.

-4-Research fields of the Center's faculty members and their contact information

Name

Research fields and keyword

E-mailAkira Nishizono

Research fields: Research for host-a24zono@oita-u.ac.jp/Takaaki Yahiro

parasite relationship in Viral infections and/ takaaki-816@oita-/Kazunoridevelopment of therapeutic- andu.ac.jp

Kimitsuki

Preventive-strategy/ k-kimitsuki@oita

Keyword: Rabies virus, SFTS virus-u.ac.jp

https://researchmap.jp/read_0019201
https://researchmap.jp/tyahiro

Yoshio Yamaoka

Research fields: Pathogenesis andyyamaoka@oita-

antimicrobial resistance of Helicobacter

u.ac.jppylori and gastric/intestinal microbiome
Keyword: Helicobacter pylori, genome
analysis, antimicrobial reesistance,
microbiome
https://researchmap.jp/yoyamaoka

Tsuyoshi Etoh

Research fields: Oncolytic Viral Therapy forteto@oita-u.ac.jp

Cancer, Gastroenterological Surgery,
Minimally Invasive Therapy
Keyword: Oncolytic virus, Bacterial
infection biology, Antibiotics-resistant
Helicobacter pylori, Phototherapy,
Minimally invasive therapy
Hitomi Mimuro

Research fields: Bacterial infection biology

mimuro@oita-u.ac.jp/Tomohiro

Keyword: Helicobacter pylori, Shigella,/miyoshit@oita-

MiyoshiOral bacteria, Gastrointestinal pathogenic

u.ac.jpbacteria, Pathogenicity regulation
mechanisms, Host responses,
Antimicrobial resistance (AMR), VBNC,
Phage
https://researchmap.jp/hitomimimurohttps://researchmap.jp/tomohiromiyoshi-5-Satoshi Komoto

Research fields: Rotavirus, Gastroentericsatoshik@oita-u.ac.jp

viruses
Keyword: Emerging and re-emerging
infectious
https://researchmap.jp/read0191150

Takuro Uchida

Research fields: Hepatology, Hepatitis

tuchida@oita-u.ac.jp

Virus
Keyword: HBV, HCV, hepatitis, Liverdiseases, Virus host interaction
https://researchmap.jp/takurouchida

Sakirul Khan

Research fields: Comprehensive researchsakirul@oita-u.ac.jp

on emerging and re-emerging viral
infections (notably Rhabdoviruses,
Flaviviruses, and SARS-CoV-2) anddevelopment of repurposing
drugs/therapies.
Keyword: Infectious disease epidemiology;
Repurposing drugs/therapies
https://researchmap.jp/MSI_KHAN

Kazufumi

Research fields: Pseudomonas aeruginosa

Hiramatsu

infection, Antimicrobial Resistance (AMR)

hiramats@oita-u.ac.jp

Keyword: Antimicrobial resistant pathogen,Pseudomonas aeruginosa, Hospitalacquired infection, Antimicrobial therapy
other than antibiotics
https://researchmap.jp/read0161428

Naoto Uemura

Research fields: Research anddevelopment of novel therapeutics andvaccines
https://www.med.oitau.ac.jp/clinical_pharmacology/en_kenkyu.html-6-uemura@oita-u.ac.jp

Masao Ogata

Research fields: Hematology,

mogata@oita-u.ac.jp

Hematopoietic stem cell transplantation,
Viral infection
Keyword: Human herpesvirus 6,
immunodeficiency-related viral infections
https://researchmap.jp/read0207324

Takashi Kobayashi

Research fields: Immunology, Parasitology

kansen@oita-u.ac.jp

Keyword: Infectious immunity,
Disease model, Virulence factors
https://researchmap.jp/read0118220

Emi Hifumi

Research fields: Life science,e-hifumi@oita-u.ac.jp

Biotechnology, Antibody engineering
Keyword: Catalytic antibody, Antibody
subunit, Antiviral effecthttps://researchmap.jp/hfmread0622

Hidekatsu Iha

Research fields: Molecular epidemiology of

hiha@oita-u.ac.jp

HTLV-1, Onset/Prognostic markers for ATL
Keyword: Evolution, molecular targetingtherapyhttps://researchmap.jp/Hidekatsu_Iha

Kousaku Komiya

Research fields: pulmonary tuberculosis,

komiyakh1@oita-

Nontuberculous mycobacteriosis

u.ac.jphttps://researchmap.jp/kkomiya-7-

<Main Facilities>

Manufacturer
Name

Model
numberNo.

Machine name1

Light sheet
fluorescencemicroscope

Zeiss

Lightsheet
7

2

Confocal laser
scanning
microscope

Olympus

FV3000L4H2-BD-3

3

Real-Time PCRsystemRoche
Diagnostics

LightCycler
964

Next generation
sequencer（Long-read）

OxfordNanopore
Technologies

GridION X5

5

Next generation
sequencer（Short-read）

Illumina

iSeq 100

Main applications
Imaging of live cell,
cleared organs,organoids, model
small organisms,
oocytes, brains, etc.
Live cell/tissue
imaging and timelapse imaging.
Real-time
monitoring andanalysis of theamount of DNA
amplified by PCR.
Up to 5 samples
can be run at once,
long-readsequencing withhigh nucleotide
sequence accuracy.
Short read length
sequence※ Usagefee (offcampus
person)1 hour5,000 Yen
Setting in
preparation
1 sample
2,000 Yen

Setting in
preparation

1 sample
5,000 Yen

Single-celltranscriptome
Single-Cell
10x
Chromium
1 sample
6
analysis of
SystemGenomics
iX
9,500 Yen
hundreds to tens of
thousands of cells
Automated
Automated multiQIAxcel
capillarycapillary DNA/RNA
Setting in
7
QIAGEN
Advanced
electrophoresis
electrophoresis
preparation
Systemsystemsystem.
Kinetic analysis,
BiomolecularOctet
quantification, andSetting in
8Interaction
Sartorius
RED96eaffinity analysis inpreparation
Analysis System
System96-well plates※Half of the usage fee will be waived when used for the center’s research conducted by
RCGLID members (including joint research through this open call).
< Pathogens>
Bacteria: H. pylori, dysentery bacillus, (Mycobacterium tuberculosis)
Viruses: rabies virus, SFTS virus, rotavirus, reovirus, hepatitis B virus, hepatitis C virus,

hepatitis D virus, mosquito-borne viruses (dengue virus, Zika virus, chikungunya virus)
Parasite: Toxoplasma, Leishmania-8-Appendix 1

Regarding the handling of joint research funds by the Research Center for
GLOBAL and LOCAL Infectious Diseases, Oita University
The Research Center for GLOBAL and LOCAL Infectious Diseases (RCGLID) will handle
all accounting for this joint research expenditure amount, rather than allocating thebudget to the selected principal investigator.
The scope of expenses is as follows■ Travel Expenses(1) In order to promote joint research, please plan at least one business trip to RCGLID
for the purpose of joint use and research.
(2) Please note that only business trips to RCGLID are allowed. However, when you
present the results of your joint research results at a conference, the principal
investigator and research assistants can request the travel expenses.
(3) Travel expenses other than those of the Principal Investigator and Research
Assistants can’t be paid.
(4) Travel expenses for faculty members of the RCGLID are not allowed.
(5) Travel expenses will be calculated in accordance with the Oita University Travel
Expense Regulations and will be paid in settlement (by bank transfer).
■ Research Expenses(1) Expendables supplies
Expendables supplies are items that are directly used for joint research with RCGLID
and have a unit price of less than 100,000 yen. However, items listed in (a) through (d)below cannot be purchased even if the amount is less than 100,000 yen.
(a) Equipment and fixtures (desks, chairs, bookshelves, laboratory tables, etc.) to beprovided at each institution(b) General-purpose office supply (computers, printers, etc.)(c) Cashable items such as money certificates, tablet terminals, digital cameras, etc.
(d) Books(2) Printing expenses
Reprint and submission fees are acceptable, as long as they are clearly stated as having
been supported by Joint Research. (Only items that can be delivered within the fiscal
year)(3) Service expenses
The costs of English editing, contracted analysis, postage, and conference participation(limited to cases where the results of this research are presented) will be covered.

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