Toshinori FUJIE

Printed Nanofilm to Engineer Bioelectronic “Second Skin”

School of Life Science and Technology,
Tokyo Institute of Technology, Japan

Toshinori FUJIE
School of Life Science and Technology, Tokyo Institute of Technology, Japan

Contact : t_fujie [at sign] bio.titech.ac.jp
Please replace [at sign] with @.

Integration of flexible electronics into the living system is expected for advancing medical diagnostics and therapeutics.
Such devices should be conformable to the physical and mechanical environment of our body, in which acquired

Research Interests

biosignals should be wirelessly transmitted to external device for health-care management. In this regard, we have

Polymer chemistry, Biomaterial, Printed electronics, Wearable & implantable device, BioRobotics

nanosheet shows tens- to hundreds-of-nanometer thickness close to the scale of biomembranes [1], in which various

envisaged ultra-flexible wearable and implantable devices based on the polymer nanosheet technology. The polymer
types of polymers (e.g., biodegradable polymers, conductive polymers, and elastomers) can be formed into the ultrathin structure by spincoating, layer-by-layer and gravure coating processes. The free-standing nanosheet showedEducation
2009

flexible and adhesive properties derived from ultra-small flexural rigidity (< 10-2 nN m). In this talk, nanosheet-based
Doctor of Engineering, Department of Life Science and Medical Bioscience,
Waseda University

Professional Career2010- 2012

Postdoctoral Research Fellow, Italian Institute of Technology

2012- 2013

Research Associate, Advanced Institute for Materials Research (AIMR), Tohoku University

2013 - 2018

Assistant Professor, Department of Life Science and Medical Bioscience, School of Advanced

2015 - 2019

Researcher, Precursory Research for Embryonic Science and Technology (PRESTO), JST2018 - presentAssociate Professor (Lecturer), School of Life Science and Technology, Tokyo Institute ofdevices (namely, printed nanofilms) are introduced by combining nanosheet and printing technologies with variety of
unique inks (Fig. 1) [2]. The printed nanofilm has been utilized as a “second skin” to engineer functional bioelectronicinterface, such as ultra-conformable bioelectrodes for sports science [3] and plant biology [4], and wirelessly-powered,implantable optoelectronics for photodynamic cancer therapy [5].

Science and Engineering / Waseda Institute for Advanced Study, Waseda University

Technology / Leading Initiative for Excellent Young Researchers (LEADER), JSPS

Scientific Activities
2005 - 2015
2015 - present

Construction of polymeric nanosheets and their biomedical application

Fig 1. Printed nanofilms based on nanosheet technology. (Partially reproduced from Ref. 2.)

Integration of nano, bio, electronics for wearable and implantable device

HonorsReferences

2019

Biomaterials Science Emerging Investigators (Royal Society of Chemistry Journal)

2018

The Young Scientists’ Prize for the Commendation for Science and Technology by the Ministerof Education, Culture, Sports, Science and Technology (MEXT), Japan[ 1 ] T. Fujie, Polym. J., 48, 773 (2016).

2017

The Award for Young Investigator of Japanese Society for Biomaterials; Japanese Society for[ 2 ] K. Yamagishi, S. Takeoka, T. Fujie, Biomater. Sci., 7, 520 (2019).

Biomaterials[ 3 ] K. Yamagishi, T. Nakanishi, S. Mihara, M. Azuma, S. Takeoka, K. Kanosue, T. Nagami, T. Fujie, NPG Asia Mater.,
11, 80 (2019).

Publications[ 4 ] H. Taniguchi, K. Akiyama, T. Fujie, B. Chem. Soc. Jpn., 93, 1007 (2020).

1. Suematsu, Y., Tsai, Ya An., Takeoka, S., Franz, C.M., Arai, S. Fujie, T. J. Mater. Chem. B, 8, 6999-7008 (2020).

[ 5 ] K. Yamagishi, I. Kirino, I. Takahashi, H. Amano, S. Takeoka, Y. Morimoto, T. Fujie, Nat. Biomed. Eng., 3, 27 (2019).

2. Yamagishi, K., Nakanishi, T., Mihara, S., Azuma, M., Takeoka, S., Kanosue, K., Nagami, T., Fujie, T. NPG Asia Mater., 11, 80 (2019).
3. Yamagishi, K., Kirino, I., Takahashi, I., Amano, H., Takeoka, S., Morimoto, Y., Fujie, T. Nat. Biomed. Eng., 3, 27-36 (2019).
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