FY2023 Open Call Guidelines for Joint Research, Research Seeds
Research Center for Global and Local Infectious Diseases, Oita University
Research Center for Global and Local Infectious Diseases (RCGLID), Oita University
promotes educational and research activities in collaboration with universities, research
institutes, and international organizations in Japan and abroad. The center is conducting
research activities and medical human resource development that can confront glocal(global/local) infectious diseases beyond national and prefectural borders.
At this center, we will elucidate the microbial infections such as virology and bacteriology,
analyze their genomic information, and comprehensively elucidate the pathophysiology of
infections based on the findings obtained from them. We seamlessly link a series of areasfrom basic research to clinical practice, including drug discovery (prevention, therapeutic
drug development, and clinical trials), which is one of our strengths. In addition, we will carryout comprehensive research with an eye on global and local infectious diseases.
We are pleased to announce the following open call for applications as a joint research
project of the Center.

1. Outline for Call
(1) Call for Proposals
We will accept applications in two categories: A) Joint Research and B) Research Seeds.
The applicant (Principal Investigator), in cooperation with the faculty member in charge of theCenter, will conduct joint research by setting up a research proposal in accordance with thetheme.
A) Joint Research(Maximum application amount: 1,000,000 yen/proposal, FY 2023)
The applicant (Principal Investigator), in cooperation with the faculty member in charge of theCenter, will conduct joint research by setting up a research proposal in accordance with thetheme listed in Appendix 1.
In particular, the Center will provide priority support for research areas of international andacademic importance that are strategically implemented by the Center.
Research Period：Up to 3 years
B) Research Seeds(Maximum application amount: 300,000 yen/proposal, FY 2023)
In this category, we call for proposals in which the applicant conducts research on infectious
diseases based on new ideas in collaboration with the Center's faculty members, with the
expectation of expanding the scope of research and promoting collaborative research.
Applicants should consult with the Center's faculty members to determine their research
topics and apply.
Research Period：Up to 2 years*1 For continuing proposal, please use the same Research Topic as the previous fiscal year.
*2 The expenses for FY2023 should be completed by the end of February 2024.
(2)Application Requirements
The applicant must be a researcher of a research institution, such as a faculty member of
any university, or a researcher who is recognized by the director as having research ability
equivalent to that of a faculty member.
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We welcome applications from researchers, including young researchers, female
researchers, and foreign researchers within the research organization, especially as Principal
Investigators.
Graduate students are not eligible to apply. However, graduate students may be included
as a member of the research team.
(3) Research Period
You can indicate a research plan for multiple years( A)Joint Research: up to 3 years,B)Research Seeds: up to 2 years. ). However, the budget execution period is within FY2023.
Please submit Application Form every year because the selection review will be conductedannually.
(4) Determination of the amount available and allocated for each application
A) Joint Research maximum 1,000,000JPY/FY
The Center will review the allocated amount and determine the adopted amount.
Additions to the amount allocated
If the Principal Investigator of each proposal meets the following requirements, an additionalamount of up to 300,000 JPY per proposal may be allocated.
* If you belong to an overseas institution*If you are 39 years old or younger as of April 1, 2023.
* For female researchersB) Research Seeds maximum 300,000JPY/FY*The Center will determine the amount to be allocated based on the status of applications
and screening results.
The expenses that can be applied for "travel expenses" and "research expenses".
Funds will not be allocated directly to the Principal Investigators, and all accounting will behandled by the Center.
2. How to Apply(1) Application
Form 1: Application for Joint Research / Research Seeds Fiscal Year 2023
Form 2: Report for Joint Research Fiscal Year 2022 (*)*If you are applying continuously from the previous fiscal year, please prepare andsubmit a Form 2 report with the status as of the time of your application for the 2023
call. The final version should be submitted by April 30, 2023.
The Principal Investigator should submit the application (Form 1) after conducting asufficient discussion with the corresponding faculty member of the Center in advance, by email, or by other means.
For submission, please send a converted PDF file as an attachment by e-mail to thefollowing contact person. Please keep your application no longer than four (4) pages.

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【Contact person】
Research Center for Global and Local Infectious Diseases, Oita University
E-mail: glocal@oita-u.ac.jp
Tel: +81-97-586-5444
Homepage: https://www.oita-glocal.jp/en/index.html(2) Deadline for application
5:00 p.m. , February 8, 2023 (Wednesday) （JST）(3) Acceptance or Rejection
Applicants will be notified of the outcome by the beginning of April 2023. In the review
process, the adopted amount will be determined based on the number of applicants, thecontents of the proposal, the previous year’s report( if it is a continuation of a proposal),and the appropriate amount for the project.
Therefore, the adopted amount may be reduced than the application amount.
Name and affiliation of the principal investigator, the title of the research project, andthe results of the research will be made public on the Center's website and in its annual
report, etc., for the adopted research projects.
(Reference) Review perspective(1) Academic importance and validity of the research topic.
(2) Validity of research plan and methods.
(3) Originality and innovation of the research topic.
(4) Utilization of the Center.
(5) Contribution to the region and the world.
(6) Validity of the use expenses.
3. Responsibilities of the Principal Investigator after Adoption(1) Report of Research Results
The Principal Investigator is required to submit the "Report on Joint Research Results"
within 30 days after the end of the research period of each fiscal year. The results of this joint
research may be presented at a result reporting meeting for evaluation purposes.
(2) Publication of results
In principle, the results of this joint research must be published in an academic paper orpresented at an academic conference (with proceedings) collaborated with a faculty memberof the Center. Please be sure to indicate in the Acknowledgments section that these are theresults of the conducted joint research.
【English】
Example 1. This work was (partly) conducted by the joint research program of the ResearchCenter for GLOBAL and LOCAL Infectious Diseases、 Oita University (#####)
Example 2. This work was (partly) supported by the Research Center for GLOBAL and
LOCAL Infectious Diseases、 Oita University(#####)“#” means the adoption number

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Please inform us of your results by e-mail, and submit one copy of the reprint (PDF is
acceptable) or one copy of the poster to us: glocal@oita-u.ac.jp
We may contact you regarding follow-up surveys on the research results after the joint
research period.
The submitted reports and papers will be reported in the Center's activity reports, annual
reports, the Center’s website, etc. In addition, we plan to publicize outstanding researchfindings in mass media. When publicizing with the mass media, we will make adjustments
after we have inquired in advance whether or not the information can be disclosed.
(3) Handling of Intellectual Property Rights
If any intellectual property has been created through this Joint Research, please contact theCenter's Faculty and Research Collaborators before filing an application, etc., and also
contact the department in charge of intellectual property at the organization to which you
belong. The share of rights, application procedures, etc. will be determined throughdiscussion.
4. Other(1) Disclosure of Information
In the case that information disclosure is requested by an external party, the accepted
application form may be disclosed except for the information that can be personally identified.
In the course of conducting research, please mark any part that you do not want to bedisclosed (such as descriptions including originality) with an underline in the application form.
It will be considered at the time of disclosure.
(2) Personal Information, etc.
We will strive to protect personal information obtained in relation to this recruitment inaccordance with the personal information protection policy of the Oita University.
These guidelines are subject to the approval of the 2023 budget, Oita University.
Therefore, please note that there is a possibility that the contents and the adopted
amount may change.

4Appendix 1
Research fields of the Center's faculty members and their contact information
Name

Research fields and keyword

E-mailAkira Nishizono

Research fields: Research for host-a24zono@oita-u.ac.jp/Takaaki Yahiro

parasite relationship in Viral infections and/ takaaki-816@oita-

development of therapeutic- andu.ac.jp

Preventive-strategy
Keyword: Rabies virus, SFTS virus
https://researchmap.jp/read_0019201
https://researchmap.jp/tyahiro

Yoshio Yamaoka

Research fields: Pathogenesis andyyamaoka@oita-u.ac.jp

antimicrobial resistance of Helicobacter
pylori and gastric/intestinal microbiome
Keyword: Helicobacter pylori, genome
analysis, antimicrobial reesistance,
microbiome
https://researchmap.jp/yoyamaoka

Masayuki Ohta

Research fields: bariatric/metabolic

ohta@oita-u.ac.jp

surgery, portal hypertension, hepato-biliary
pancreatic surgery, travel medicine
Keyword: bariatric surgery, metabolic
surgery, intestinal bacterial flora, COVID19, travel medicine, inbound, medical
interpreter, plain Japanese
https://researchmap.jp/read0119454

Hitomi Mimuro

Research fields: Bacterial infection biology

mimuro@oita-u.ac.jp/Tomohiro

Keyword: Helicobacter pylori, Shigella,/miyoshit@oita-u.ac.jp

MiyoshiOral bacteria, Gastrointestinal pathogenic
bacteria, Pathogenicity regulation
mechanisms, Host responses,
Antimicrobial resistance (AMR), VBNC
https://researchmap.jp/hitomimimurohttps://researchmap.jp/tomohiromiyoshi

5Satoshi Komoto

Research fields: Rotavirus, Gastroentericsatoshik@fujita-hu.ac.jp

viruses
Keyword: Emerging and re-emerging
infectious
https://researchmap.jp/read0191150

Kazufumi

Research fields: Pseudomonas aeruginosa

Hiramatsu

infection, Antimicrobial Resistance (AMR)

hiramats@oita-u.ac.jp

Keyword: Antimicrobial resistant pathogen,Pseudomonas aeruginosa, Hospitalacquired infection, Antimicrobial therapy
other than antibiotics
https://researchmap.jp/read0161428

Naoto Uemura

Research fields: Research anduemura@oita-u.ac.jp

development of novel therapeutics andvaccines
https://www.med.oitau.ac.jp/clinical_pharmacology/en_kenkyu.html

Masao Ogata

Research fields: Hematology,

mogata@oita-u.ac.jp

Hematopoietic stem cell transplantation,
Viral infection
Keyword: Human herpesvirus 6,
immunodeficiency-related viral infections
https://researchmap.jp/read0207324

Takashi Kobayashi

Research fields: Immunology, Parasitology

kansen@oita-u.ac.jp

Keyword: Infections immunity,
Disease model, Virulence factors
https://researchmap.jp/read0118220

Emi Hifumi

Research fields: Life science,
Biotechnology, Antibody engineering
Keyword: Catalytic antibody, Antibody
subunit, Antiviral effecthttps://researchmap.jp/hfmread0622

6

e-hifumi@oita-u.ac.jp

Hidekatsu Iha

Research fields: Molecular oncology,

hiha@oita-u.ac.jp

Immunobiology
Keyword: HTLV-1
https://researchmap.jp/Hidekatsu_Iha

Kousaku Komiya

Research fields: pulmonary tuberculosis,
Nontuberculous mycobacteriosis
https://researchmap.jp/kkomiya

7komiyakh1@oita-u.ac.jp

<Main Facilities>
No.

Machine name

Manufacturer
Name

Model
number1

Light sheet
fluorescencemicroscope

Zeiss

Lightsheet 72

Confocal laser
scanning microscope

Olympus

FV3000L4H2-BD-3

3

Real-Time PCRsystemRoche
Diagnostics

LightCycler
964

Next generation
sequencer（Longread）

OxfordNanopore
Technologies

GridION X5

5

Next generation
sequencer（Shortread）

Illumina

iSeq 100

6Single-Cell System

10x
Genomics

Chromium
iX

7

Automated capillaryelectrophoresis
systemQIAGEN

QIAxcelAdvanced
System8

BiomolecularInteraction Analysis
SystemSartorius

Octet
RED96eSystemMain applications
Imaging of live cell, clearedorgans, organoids, model
small organisms, oocytes,
brains, etc.
Live cell/tissue imaging andtime-lapse imaging
Real-time monitoring andanalysis of the amount of
DNA amplified by PCR,
compatible with 8-tube and
96-well plates, and capableof multi-detection of FAM,
HEX, Texas RED, and Cy5
Up to 5 samples can be run
at once, long-read (several
kb to hundreds of kb)
sequencing with highnucleotide sequence
accuracy, whole genomic
or transcriptome analysis
Short read length
sequence
Single-cell transcriptome
analysis of hundreds totens of thousands of cells
Automated multi-capillary
DNA/RNA electrophoresis
system. Up to 96 samples,
nucleic acid concentration
detection of 0.1 ng/μL or
more, digital data output
Kinetic analysis,
quantification, and affinity
analysis in 96-well plates*1 is scheduled to be introduced in February 2023
< Pathogens>
Bacteria: H. pylori, dysentery bacillus, (Mycobacterium tuberculosis)
Viruses: rabies virus, SFTS virus, rotavirus, mosquito-borne viruses (dengue virus, Zika virus,
chikungunya virus)
Parasite: Toxoplasma, Leishmania

8Appendix 2

Regarding the handling of joint research funds by the Research Center for
GLOBAL and LOCAL Infectious Diseases, Oita University
The Research Center for GLOBAL and LOCAL Infectious Diseases (RCGLID) will handle
all accounting for this joint research expenditure amount, rather than allocating thebudget to the selected principal investigator.
The scope of expenses is as follows■ Travel Expenses(1) Please plan at least one business trip to the RCGLID for the purpose of joint researchpromotion.
(2) Please note that only the business trips to RCGLID are allowed. However, when you
present the results of your joint research results at a conference, the principal
investigator and research assistants can request the travel expenses.
(3) Travel expenses other than those of the Principal Investigator and Research
Assistants can’t be paid.
(4) Travel expenses for faculty members of the RCGLID are not allowed.
(5) Travel expenses will be calculated in accordance with the Oita University Travel
Expense Regulations and will be paid in settlement (by bank transfer).
■ Research Expenses(1) Expendables supplies
Expendables supplies are items that are directly used for joint research with RCGLID
and have a unit price of less than 100,000 yen. However, items listed in (a) through (d)below cannot be purchased even if the amount is less than 100,000yen.
(a) Equipment and fixtures (desks, chairs, bookshelves, laboratory tables, etc.) to beprovided at each institution(b) General-purpose office supply (computers, printers, etc.)(c) Cashable items such as money certificates, tablet terminals, digital cameras, etc.
(d) Books(2) Printing expenses
Reprint and submission fees are acceptable, as long as they are clearly stated as having
been supported by Joint Research. (Only items that can be delivered within the fiscal
year)(3) Service expenses
English proofreading fee, Commissioned analysis fee, and postage is eligible9