The annual meeting of

The 11th Asian Society of
Nuclear Medicine Technology
in Osaka, Japan

18th November, 2023
Grand Front Osaka Tower-C, 8F
President

Tomoaki Yamamoto, RT, PhD(Kyorin University)

Vice president

Kohei Hanaoka, RT, PhD(Kindai University Hospital)

Contents
Greetings

2

Map of venue

4

Registration of the 11th ASNMT

5Introduction of chairpersons

5

Speaker’s regulations

6

Information of presidential reception

7

Program

8

Abstracts
Oral session 1

13

Oral session 2

19

Poster session

27

Board members of ASNMT

35

Advertisements by sponsored companies

36

1Long time no see,all of friends
President

Tomoaki YAMAMOTO, Ph.D.

Dear Friends and Colleagues, Dear ASNMT Members
It’s very honor to be held the annual conference of the 11th Asian Society of Nuclear
Medicine Technology (ASNMT) in Osaka, Japan, and I’m really pleasure on behalf of
JSNMT and ASNMT board member to welcome you to the meeting, that will take placeat Grand Front Osaka in Osaka, Japan November 18th, 2023.
COVID-19 pandemic had stricken confuse to people's heart in whole world. We had
to wear a mask, keep a physical distance, cancel a lot of conferences. Web tools areuseful for virtual meetings or conferences, however, the discussions are very slow. At
least, we are able to join with all of you on face to face after a long time.
In nuclear medicine technology fields, standardization of imaging and therapy using
radiopharmaceuticals is very important for quantification and theragnostic. We should
definitize the role of nuclear medicine technology in each country, and share them.
ASNMT is able to show a leadership not only Asia, but also the other regions. We hope
many colleagues discuss and exchange precious opinions in this meeting, nuclear
medicine technology contribute to health of peoples in whole world.
Osaka is very exiting town, there are a lot of nice foods and places. I hope you will
enjoy your stay.

2

Welcome to Osaka,
Welcome to ASNMTVice president

Kohei HANAOKA, Ph.D.

The members of the organizing committee and myself are delighted to present the'11th Annual Conference of the Asian Society of Nuclear Medicine Technology(ASNMT)' and extend a warm welcome to all participants attending the 63rd JSNM
and 43rd JSNMT conferences in Osaka from November 16th to 18th, 2023.
ASNMT is designed to provide updates on the latest developments in the field of
nuclear medicine technology and related aspects in Asia. After two years of virtual
meetings, we are looking forward to the joy of reconnecting with each other in person.
We anticipate engaging in valuable scientific sessions. We express our deep
appreciation for the hard work and dedication of all the organizing committee members
in preparing for this conference. We would also like to extend our gratitude to JSNMT
for their invaluable support and continuous follow-up. We are committed to making
this event a resounding success.
We hope you enjoy your time in Osaka!

3The annual meeting of Asian Society of Nuclear Medicine Technology
Information of Venue
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Umekita Ship Hall

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4

Registration of the 11th ASNMTThe registration time is 12:00 to 13:00. The reception of the 11th ASNMT is located at
Grand Front Tower-C, room C-07 (8F). Participants confirm your name, and receive aname card, name folder, certification of attendance and abstract book at the reception.
Participants write your name and institution on the card and keep it your front in theconference and presidential reception.
For the members of JSNMT, KSNMT and TSNMT, the registration fee is free, also
students are always free. Nonmembers are requested to pay 2,000 JPY as the registration
fee in cash, which is included the presidential reception.
A graffiti wall is set in front of C-07. Participants can write your sign, illustrations or
your favorite words for your memorial. Please take a photo at there.

Introduction of Chairpersons
Oral session – 1
Mitsuha Fukami (Kyorin University, Japan)
Kao-Yin Tu (Mackay Memorial Hospital, Taiwan)

Oral session – 2
Daisuke Hasegawa (Kobe Tokiwa University, Japan)
Jun-Young Park (Yonsei University, Koran)

5

Speaker’s Regulation
Oral Presentation
Presentation data is used MS-PowerPoint for windows, and the size should be designedby 4:3 or 16:9. Windows-PC which OS is windows-11 is placed on speaker’s table. Author
installs the data to the PC during 12:30 to 13:00, and confirm it, however, practice ofspeech is not accepted. If author wants to use Mac-PC, then author prepare own PC andcable which you need by yourself and connect it to monitor cable (HDMI).
The presentation time is 7 minutes, and discussion time is 3 minutes. Especially, authorpunctual the time of presentation.

Poster Presentation
A size of poster panel is set 1,800 x 800 mm (vertical x horizontal). Author can use inthis space, however, the recommended size is 1,500 x 700 mm (vertical x horizontal). In
the poster, the title, author’s name, name of institutions and contents, also the poster isput on the panel using some magnets in 12:30 to 13:00. Poster Presentation is free
discussion. Author anticipates in front of your poster during presentation time.

6

Information of presidential reception
We welcome you to a presidential reception which is held a Japanese restaurant close toconference venue. Staffs inform you to there after conference, please follow him/her. We
move to there on foot, and it takes approximate 15 min from Tower-C.
Data and Time; 18th November 2023
Venue;

6:00pm to 8:00pm

KIZASHI Umeda-Kita-Shinchi
https://c794000.gorp.jp/
in HOTEL MYSTAYS PREMIER Dojima, 3F
https://www.mystays.com/en-us/hotel-mystays-premier-dojima-osaka/

It takes about 15 minutes on your foot.

7

Programannual meeting of

The 11th Asian Society of Nuclear Medicine Technology
Date;
Venue;

18th November, 2023
Grand Front Osaka Tower-C, the 8th Floor

Tower C, Room C-06; Committees meeting of ASNMT(Board members only)
10:00 – 12:00

Steering committees meeting
Japan, Korea and Taiwan board members

Tower C, Room C-07; The 11th Annual Conference of ASNMT
12:00 – 13:00

Registration and presentation data check12:30 – 13:00

Putting up the posters on the panels

13:10 – 13:25

Opening ceremony
Video message from EANM-Tech Community
Welcome greeting813:30 – 14:20

Oral session – 1
Chairpersons; Mitsuha Fukami (Japan)
KAO-Yin Tu (Taiwan)

O-01

Broad quantification calibration of various isotopes for quantitative analysis
and the assessment of their SUVs in a SPECT/CT scanner
Asan Medical Center

Hyunsoo Ko
O-02(Korea)The usefulness of acquire during step method compared to step-and-shoot andcontinuous method

Kobe Tokiwa University, Faculty of Health Science, Department of Radiological Technology

Kotaro Tokunaga
O-03(Japan)A Rare Finding of Primary Aortoduodenal Fistula by Gastrointestinal
Bleeding SPECT/CT Scan
Hsinchu Mackay Memorial Hospital

Chun-Liang Kuo
O-04(Taiwan)Optimizing Nuclear Medicine Imaging Workflow for Kidney Examination
Assessment
Taichung Tzu Chi Hospital

Tien-Hsin Chang
O-05(Taiwan)Evaluation of Short Acquisition Image with Automatic Quantification
Package using Multi-CZT Scanner
Division of Radiology, Department of Medical Technology, Osaka University Hospital

Kaede Tsuzura

14:20 - 14:40

Tea Break

9(Japan)14:40 - 15;30

O-06

Oral session – 2

Chairpersons; Daisuke Hasegawa (Japan)
Jun-Young Park (Korea)
A Discussion on Image Analysis in 18F-Florbetaben PET/CT
Severance Hospital

Yong-hoon CHOI
O-07

(Korea)Comparison of Radiation Exposure for Healthcare Personnel during PETCTScans Using Automated and manual Procedure
Department of Nuclear Medicine, Landseed International Hospital

Hui-Ping Chen
O-08

(Taiwan)Discussion the deviation of effective renal plasma flow analysis between
different technologist
Tri-Service General Hospital

Hsiu-Shan Wang
O-09

(Taiwan)Monte Carlo Simulation Study on Whole-body SPECT with TlBr
Semiconductor Detector
Department of Radiological, Technology, Faculty of Medical Technology, Teikyo University

Sousei Kawasaki
O-10(Japan)Comparison of results based on storing samples for Plasma Renin Activity(PRA) test
Asan Medical Center

Jin Joo Choe

10

(Korea)15:30 - 16:10

P-01

Poster session (free discussion)

Implementation of Entrustable Professional Activities (EPAs): Experiences at
NM field in Taiwan
Taichung Veterans General Hospital

Jui-Yin Kung
P-02

(Taiwan)

How a Laboratory Complaint Led to the Discovery of a Hidden Drug Effecton Pituitary Hormones
Cathay General Hospital

Ya-Chieh Fang
P-03

(Taiwan)Influence of the distance between the radiation source and the detector when
the GFR test
En Chu Kong Hospital

Li-Ru Liu
P-04

(Taiwan)Radioimmunoassay Reagents Survey and Evaluation
National Cancer Center

Ji Na Kim
P-05

(Korea)Effect of hemolysis sample on the result of nuclear medicine blood test
Ajou University Medical Center

Jin Tae Kim
16:10 - 16:20

Information of next ASNMT meeting

16:20 - 16:40

Closing ceremony and ASNMT flag passing ceremony
Greeting of the next congress chair
Flag passing Japan to Korea

18:00 - 20:00

Presidential Reception at Japanese restaurant

11(Korea)12Oral Session - 1
13：30 – 14：20

13

O-01
Korea

Broad quantification calibration of various isotopes for quantitative
analysis and the assessment of their SUVs in a SPECT/CT scanner
Hyunsoo Ko, Jaemin Choi, Soonki Park
Asan Medical Center

Purpose : Broad Quantification Calibration(B.Q.C) is used for the quantitative analysis of theStandard Uptake Value(SUV) in a SPECT/CT scanner. B.Q.C was performed for Tc-99m, I-123, I131 and Lu-177. The purpose of this study was to lay the groundwork for the quantitative analysis
with various isotopes in a SPECT/CT scanner. Materials and Methods : The B.Q.C procedure has
two steps: the first is point source sensitivity cal. and the second is volume sensitivity cal. to
calculate the volume sensitivity factor(VSF) using a cylinder phantom. The SPSS software wasused to perform Mann-Whitney test to analyze the difference in the SUVs obtained using the Intevo
16 and Intevo Bold. Results :The SUVs obtained using the Intevo 16 and Intevo Bold showed nostatistically significant(p>0.05). Conclusion : In the past, only qualitative analysis was possibleusing a gamma camera. On the other hand, it is possible to not only acquire anatomic localization,
3D tomography, but also achieve the quantitative analysis of the SUVs in SPECT/CT scanners. We
could lay the groundwork for quantitative analysis of various isotopes, such as Tc-99m, I-123, I131 and Lu-177 by B.Q.C. Moreover, periodic calibration is necessary to maintain the precision of
the quantitative evaluation. Thus, we can perform the quantitative analysis of isotopes in follow-up
scans obtained using the SPECT/CT examinations and evaluate therapeutic responses intheranostics.

Keywords

Broad Quantification Calibration, Quantitative Analysis, SUV,
SPECT/CT

14

O-02
Japan

The usefulness of acquire during step method compared to step-andshoot and continuous method
Kotaro Tokunaga, Daisuke Hasegawa, Takuma Minoda, Syoki Nagasako, Manato
Fujiwara, Akari Ouchi, Moe Maura, Hiroyuki Tsushima
Kobe Tokiwa University, Faculty of Health Science, Department of RadiologicalTechnology
PurposeThe SIEMENS SPECT machine has the acquire during step (ADS) acquisition mode.
ADS is the acquisition method similar to conventional step-and-shoot mode and the projection dataobtained by the detector-to-detector movement is added to the next projection data. The aim of thisstudy was to evaluate the usefulness of Acquire During Method (ADS) compared to step-and-shoot(SS) and continuous (Cont) method.
Methods
JSP phantom was acquired on SPECT/CT systems (Symbia Intevo 16) to evaluate image spatial
resolution. Acquisition mode was set to SS, Cont and ADS, and sampling angles were set to 2, 3, 4,
5, and 6. SPECT images were reconstructed using filtered back projection (FBP), and ordered
subsets conjugated gradient minimization (OSCGM). The profile curve was drawn on line source
and two types of full width at half maximum, FWHMtang and FWHMrad, were calculated.
Results
The FWHMtang of SS, Cont and ADS in FBP images were 11.78±0.16, 11.74±0.13 and 12.12±0.25
at 2 degrees of sampling, respectively, and 11.97±0.40, 13.04±0.38 and 12.24±0.73 at 6 degrees ofsampling, respectively. FWHMtang of ADS images showed better spatial resolution than Cont. For
OSCGM images, FWHM did not show a constant trend due to differences in sampling angle andacquisition method.
Conclusion
It was suggested that the ADS method does not degrade compared to the SS and cont methods interms of spatial resolution, and can be used in the same way as other acquisition methods.

Keywords


SPECT, acquisition method, FBP, OSCGM, FWHM


15

O-03
TaiwanA Rare Finding of Primary Aortoduodenal Fistula by Gastrointestinal
Bleeding SPECT/CT Scan
Chun-Liang Kuo
Department of Nuclear Medicine, Hsinchu Mackay Memorial Hospital, Hsinchu,
TaiwanA year ago, a 67-year-old man was hospitalized after suffering from coffee ground vomiting, tarrystool passage, and abdominal colic pain. Following this, he was recurrently admitted due togastrointestinal (GI) active bleeding and hypovolemic shock. Intermittent and spontaneously stop
bleeder was too difficult to find after multiple GI endoscopy, angiography, computed tomography
angiography (CTA), capsule endoscopy, and 99mTc-red blood cell (RBC) scan. He received
supportive treatment every time and was discharged without signs of rebleeding. Therefore, wesuggested that he be admitted longer to find the bleeder. Finally, CTA was performed soon after the
bleeding, and a small aortic aneurysm was found at the renal level, which seemed to be related tothe duodenum. A 99mTc-RBC single-photon emission computed tomography/computed tomography(SPECT/CT) scan was arranged when the patient had bleeding symptoms and showed an active
bleeder at the duodenum level. Consequently, according to clinical symptoms (intermittent massive
GI bleeding with hypovolemia shock, dizziness, dark red stool passage, bloody vomitus), abdominal
CTA, and 99mTc-RBC SPECT/CT scan, duodenal bleeding may be caused by the small aneurysm,
and primary aortoduodenal fistula was highly suspected. Afterwards, he underwent duodenum
excision and duodenum-jejunum anastomosis. A 7-mm saccular aneurysm arising from the anteriorwall of the abdominal aorta near the left renal artery was found during surgery; thus, percutaneous
intravascular stenting of the abdominal aorta was arranged. Accordingly, the symptoms of GI
bleeding improved postoperatively.

Keywords

Gastrointestinal active bleeding; Computed tomography angiography;
99mTc-red blood cell scan; Single-photon emission computed
tomography/Computed tomography, Primary aortoduodenal fistula

16

O-04
TaiwanOptimizing Nuclear Medicine Imaging Workflow for Kidney
Examination Assessment
Tien-Hsin Chang
Taichung Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Taichung, Taiwan

Background: Nuclear medicine's role in assessing kidney function, particularly in compromised
states, is pivotal. It aids clinicians in discerning proper kidney functionality and drug metabolism
rates, thereby serving as a cornerstone for diagnosing kidney ailments, evaluating damage extents,and monitoring function shifts.
Methods and Results: An exploration into effective renal plasma flow (ERPF) encompassed 76
patients (54% male, 46% female). Drug dosages pre and post-injection were gauged. Collimatorsensitivity (CS) quantification to ascertain counting efficiency ensued. A median CS of 2053
emerged. The GE Xeleris 3.0 workstation facilitated data analysis, with consistent techniciandelineated regions of interest (ROI). ERPF computation methods were juxtaposed: original versus
Collimator adjusted.
Via IBM SPSS Statistics, paired samples t-tests and Bland-Altman analyses transpired. A
substantial correlation (0.996) and insignificance (p = 0.000) denoted agreement between the two
methods. Bland-Altman plot analysis affirmed the accord, signifying robust consistency.
Discussion: Traditional nuclear medicine departments grapple with demanding timetables.
Incorporating the revised collimator technique, efficiency ameliorates, invigorating workflow. The
revised collimator method offers clinical merits: streamlined and efficient examinations, invaluable
for bustling high-volume departments.

Keywords

ERPF, collimator sensitivity, LEHR

17

O-05
Japan

Evaluation of Short Acquisition Image with Automatic Quantification
Package using Multi-CZT Scanner
Kaede Tsuzura1), Takashi Kamiya1), Koushi Kotani1), Hidetaka Sasaki1), Hajime
Ichikawa2),
1)

Division of Radiology, Department of Medical Technology, Osaka University
Hospital2)
Department of Radiology, Toyohashi Municipal Hospital
Introduction:
VERITON-CT (Spectrum Dynamics Medical), a Multi-CZT detector mounted gamma camera, hasbeen reported to have higher sensitivity than Anger-type camera equipped NaI detector. Several
reports were analyzed by automatic quantification package for bone SPECT, (Hone Graph: BoneSPECT Conference). In this study, a bone-specific phantom and Hone Graph software were used toclarify detectability for short acquisition.
Methods:
In a SIM2 bone phantom (Taisei Medical) simulating the thorax region, was filled with 99mTc
solution of 50 kBq/mL in normal bone and 300 kBq/mL in bone metastases (28, 22, 17, 13 mm
sphere). Acquisition time was 2 and 10 minutes/bed. SPECT images were reconstructed by iterative
method (subsets; 8, iteration; 2-14, matrix; 256×256, pixel size; 2.46 mm, FWHM of Gaussian filter(GF); 5, 10 mm). By using Hone Graph software, SPECT images were analyzed about detectability
score (DS) evaluated by both percent of detectability equivalence volume (%DEV) and contrast
noise ratio (CNR).
Results:
With optimal parameters of iterations; 8, subsets; 8 and GF; 10 mm for 2 and 10 minutes/bed
acquisition, %DEVs were 31.25 and 44.73 (> 14.21), and CNRs were 11.46 and 12.71 (> 11.36),
respectively. Mentioned above, DSs of 17 mm sphere received an excellent evaluation for 2 and 10
minutes/bed acquisition.
Conclusion:
Based on Hone Graph software, bone SPECT images acquired in 2 minutes/bed by VERITON-CT
were verified the feasibility.

Keywords

VERITON-CT, Hone Graph, SPECT/CT, bone scintigraphy, CZT

18

Oral Session - 2
14：40 – 15：30

19

O-06
Korea

A Discussion on Image Analysis in 18F-Florbetaben PET / CT
Yong-Hoon Choi, Jae-Sam Kim, Young-Kag Bahn, Han-Sang Lim
Department of Nuclear Medicine, Severance Hospital, Yonsei University Health
System, Seoul, Korea[Purpose] 18F-Florbetaben (FBB) Readings are made by visually comparing the signal strengths ofgray matter and white matter. We intend to evaluate the usefulness of image analysis by comparing
quantified image analysis with readout.
[Materials and Methods] Based on the reading results, 100 patients were divided into a negative
scan and a positive scan, and 300 MBq of FBB was injected, and images were taken 90 minutes
later for 20 minutes. The equipment was a Discovery 600 (GE Healthcare, MI, USA). Four regionsof interest were lateral temporal lobes, frontal lobes, posterior cingulate & precuneus, and parietal
lobes. For image analysis, SUVratio (SUVr) was calculated by dividing each SUVmean by the
cerebellum, and the average SUVr in the entire area was performed. Statistical analysis analyzed
ROC Curve, Independent sample t-test, and Kappa test.
[Results] The average SUVr cutoff in the entire area was 1.23. Concordance with the read results
using cutoff was 95% for negative and 92% for positive. As a result of the t-test, there was astatistically significant difference between the groups (P < 0.05), and the Kappa statistical result
showed a high degree of agreement with 0.867 (P < 0.05).
[Conclusion] The results of image analysis were statistically significant and showed a high degreeof agreement with the reading results. If quantified FBB image analysis is used as an auxiliaryindicator, it is thought to be helpful in reading.

Keywords

SUVr, Cutoff

20

O-07
TaiwanComparison of Radiation Exposure for Healthcare Personnel during PETCTScans Using Automated and manual Procedure
Hui-Ping Chen, Tzu-Hsuan Wu, Sheng-Pin Changlai
Department of Nuclear Medicine, Landseed International Hospital

Method: The staff wore portable surveymetter on their wrist and chest to simulate extremity andtrunk dose rates during injections. Dose rates were separately collected from 36 patients for bothautomated and manual injections of 18F-FDG. The highest values recorded during injection toconservatively calculate dose received for 18F-FDG injection using the automated and manual
injection methods. During data analysis, all 18F-FDG activities were normalized to standard activity(10 mCi) for analysis and comparison. Results: Used of the automated injection system, The staff
received an average dose rate of (1.86±1.16/1.47±0.82) μSv/h at extremities and trunk, with anaverage injection time of (147±4) seconds. The calculated average dose received by Staff for each
18F-FDG injection was (76±46/60±32) nSv at the extremities and trunk. In contrast, when using

manual injection, The staff received an average dose rate of (567.0±230.1/113.23±70.66)) μSv/h at
extremities and trunk, with an average injection time of (64±9) seconds. The calculated average
dose received by staff for each 18F-FDG injection was (1.02±0.45)×104/(2.01±1.27)×103 nSv atthe extremities and trunk. Based on these results, it can be concluded that extremity dose during
automated injection was 1/130 (0.77%) of that during manual injection, and trunk dose was 1/34
(3.0%) of that during manual injection. Conclusion: Using an automated injection system for drug
administration significantly reduces the dose received.

Keywords

18F-FDG

21

O-08
TaiwanDiscussion the deviation of effective renal plasma flow analysis
between different technologist
Hsiu-Shan Wang, Tzai-Yang Chen, En-Shih Chen, Tien-Juei Hsu, Kuan-Wen
Shih, I-Feng Cheng, Cheng-Yi Cheng
Department of Nuclear Medicine of Tri-Service General Hospital, Taipei, Taiwan

Purpose:The main purpose of using nuclear medicine to detect kidney disease is to understand the extent towhich kidney function is affected by disease. The most important physiological tests include renal
blood flow, effective renal plasma flow (ERPF), and renal glomerulus. Filtration rate (GFR) andrenal excretion function, etc. These methods were affected by the nuclear medicine dose or thelocation and size of ROI (region of interest). The purpose of this study is to discuss the deviation of
ERPF analysis values between different technologist, and then to establish a consistent analysis
method.
Material and methods:
Select about 60 cases of kidney function examinations between 2020 to 2021, de-identify theoriginal images and replace them with numbers, and post-process the images respectively by 5
radiologists. After analyzing the EFPF values, the ten patients with the largest coefficient ofvariation were found. All the radiologists used the image of ERPF which was the closest to theaverage as the standard to analysis again.
Results:
The ERPF coefficient of variation of five radiologists analysist were between 3%~53%. The largest
ten ERPF coefficient of variation values were between 32%~53%. After analysis again, thecoefficient of variation had significantly decreased.

Keywords

effective renal plasma flow, ERPF

22

O-09
Japan

Monte Carlo Simulation Study on Whole-body SPECT with TlBr
Semiconductor Detector
Sousei Kawasaki1), Toshimune Ito2), Keitaro Hitomi3), Michael Ljungberg4),
Hirotatsu Tsuchikame5), Yuya Sekikawa6)
1)

Department of Radiological, Technology, Faculty of Medical Technology, Teikyo
University
2)
Department of Radiological, Technology, Graduate School of Health Sciences, Teikyo
University
3)
Department of Quantum Science and Energy Engineering, Graduate School ofEngineering, Tohoku University
4)
Medical Radiation Physics, Lund University
5)

Department of Radiology, Saiseikai Yokohamashi Tobu Hospital
Department of Radiological Technology, Graduate School of Health Sciences, Teikyo
University Fukuoka Campus
6)

Objective:
The development of Whole-body SPECT system with TlBr semiconductor (T-SPECT), celebrated
for high sensitivity and energy resolution, necessitated a Monte Carlo simulation validation. We
compared prototype detector measurements with T-SPECT simulations and 99mTc cerebral bloodflow imaging. Further, we evaluated clinical suitability against Whole-body SPECT system withCZT semiconductor (C-SPECT) measurements.
Methods:
Data were obtained using a 4-pixel detector with a 57Co source and T-SPECT simulations via
SIMIND, under matching conditions. Their Energy Spectrum verified each's consistency. A 3DBrain phantom was infused with 99mTc, and varied-duration data were collected using C-SPECT.
Identical conditions were mirrored in T-SPECT simulations. From these, we computed Count
profile, PSNR, SSIM, and PSD.
Results:
The T-SPECT showcased high SIMIND reproducibility. The 3D-Brain phantom revealed that TSPECT had thrice the collection count of C-SPECT. T-SPECT displayed stable PSNR and SSIM
across collection times. T-SPECT's PSD outperformed C-SPECT in all frequency domains.

23Conclusion:
T-SPECT, relative to C-SPECT, offers heightened data sensitivity. It demonstrated fewer noise
fluctuations over collection spans and a sustained likeness to the base image, underscoring its
clinical prowess.

Keywords

TlBr semiconductor, CZT semiconductor, Monte Carlo Simulation,
SIMIND, Whole-body SPECT system

24

O-10
Korea

Comparison of results based on storing samples for Plasma Renin
Activity (PRA) test
Jin Joo Choe
Asan Medical Center

The sample storage conditions are important in matters that are easily denatured in vitro. We has
consistently found a difference between the initial and re-test results in PRA test. We analyzed thedifferences in results according to the sample storage.
The 43 PRA samples were measured using the RIA and were re-tested with different storage
conditions. The first group was tested by freezing the plasma-separated samples and the second
group was tested with refrigerated EDTA sample. Based on the initial results, the results of eachgroup were compared. The re-test result of the first group showed a lower correlation than thesecond group.
When calculating the percentage based on the initial test results, the average percentage of the firstgroup is 404.9%, and R2=0.8501, and the second group was 133.8%, R2=0.9966.
In addition, 13 PRA samples were tested to verify the effect of thawing temperature. Each group
was thawed at room and refrigrated temperature. There was no significant difference in the first
test. When the second test was conducted after freezing again, both groups increased.
A comparative analysis of retesting according to differences in sample storage showed a higher
correlation the refrigerated EDTA plasma. Repeated freezing and thawing of samples, regardless ofthawing temperature, has been shown to affect results. Therefore, retesting of PRA should be recollected plasma from the original EDTA plasma to increase reproducibility.

Keywords

Plasma renin activity, Radioimmunoassay, Storage temperature

25

26

Poster Session
15：30 – 16：10

27

P-01
TaiwanImplementation of Entrustable Professional Activities (EPAs):
Experiences at NM field in Taiwan
Jui-Yin Kung1,2), Hui-Ping Chen3), Kao Yin Tu4), Yu-Ching Hsu5), Yi-Hsun Chen6),
Wan-Jo Chang7), Chen-Jung Chang2), Shih-Chuan Tsai1,2)
1)

Department of Nuclear Medicine, Taichung Veterans General Hospital
Department of Medical Imaging and Radiological Science, Central Taiwan Universityof Science and Technology
3)
Department of Nuclear Medicine, Landseed International Hospital
4)
Department of Nuclear Medicine, Mackay Memorial Hospital2)5)

Department of Nuclear Medicine, Dalin Tzu Chi Hospital
Department of Nuclear Medicine, Ditmanson Medical Foundation Chia-yi Christian6)

Hospital
Department of Nuclear Medicine, National Taiwan University Cancer Center

7)

The Taiwan Association of Medical Radiation Technologists (TAMRT) has embraced CompetencyBased Medical Education (CBME) in recent years., TAMRT convened national experts to establish
five core competencies in 2014. From 2017, Entrustable Professional Activities (EPAs) and
Milestones were introduced into national clinical instructor training programs. The nuclear
medicine team initiated the development of EPAs for "PET" and "SPECT" examinations in
2020.This year, we’re planning to complete two additional EPAs: "NM Radiopharmaceuticals and
QA" and "Isotope Therapy." An expert panel was responsible for drafting the OPAs(Observable
Practice Activity) and observation dimensions for each EPA. A nationwide survey in Marchgarnered 60 responses, and on June 10, a national expert consensus meeting was held with 43
experts in attendance. The consensus process involved literature review, consensus education
training, and the use of the Nominal Group Technique (NGT) for consensus on task names andobservation dimensions. After 42 group votes, 18 task names remained unchanged, 9 observation
dimension names were modified, 8 observation dimensions were merged, and 7 new cases wereadded or withdrawn. In addition to the development of new EPAs, TAMRT has initiated a two-year
pilot CBME program. The ultimate goal is to establish a solid foundation for CBME, emphasizing
the cultivation of practical competencies in medical radiation technology.

28

Keywords

competency-based medical education (CBME), Entrustable
Professional Activities (EPAs), Nominal Group Technique (NGT),
nuclear medicine


29

P-02
TaiwanHow a Laboratory Complaint Led to the Discovery of a Hidden Drug Effect on
Pituitary Hormones
Ya-Chieh Fang1), Pu Han1), Peng-Chia Chen1), Ching-Yang Yu1), Ching-Ling
Lin1,2)
1)

the Department of Laboratory Radioimmunoassay and the Department ofEndocrinology and Metabolism at Cathay General Hospital in Taipei, Taiwan
2)
the Department of Endocrinology and Metabolism at Cathay General Hospital in
Taipei, Taiwan
We encountered a puzzling case of a post-total thyroidectomy patient who had been on a suppressive
dose of thyroxine for decades and was found to have progressively elevated thyroid-stimulating
hormone (TSH) from the suppressive range to the hypothyroid range, despite taking an adequate
dose of thyroxine correctly. The clinician initially suspected a laboratory error and requested aretest. We verified the accuracy and precision of our TSH assay and found no issues. We suggested
a thorough medication review during our discussion with the clinician, which inspired the clinician
to focus on the timeline of the patient's TSH elevation and concurrent medication. It turned out thata dopamine antagonist, domperidone, used for gastroesophageal reflux disease (GERD), wasclosely related to the patient's hormonal profile change. Additional hormone determination,
including prolactin, also agreed with the timeline of TSH elevation.
We successfully solved a clinical dilemma by investigating a laboratory complaint and collaboratingwith the clinician. This drug effect is often overlooked and can lead to misdiagnosis or inappropriate
treatment. Clinicians should monitor pituitary hormones in patients who are on dopamine antagonist
therapy. Laboratories should have a systematic process for dealing with complaints and discussing
results with clinicians.

Keywords

Laboratory Complaint, thyroidectomy, TSH elevation, dopamine
antagonist, prolactin

30

P-03
TaiwanInfluence of the distance between the radiation source and the detector when the
GFR test
Li-Ru Liu
En Chu Kong Hospital

GFR is metabolized by the kidneys and excreted with urine. Nuclear medicine dynamic
renal/urological function measurement (GFR with Gate,s Method) mainly evaluates the function of
the kidney .
GFR is mainly used for quantitative analysis by measuring the radioactive tracer full needle, empty
needle, the uptake of the drug by the left and right kidneys, and the residual dose of the drug at the
injection site.
Pilt up effec occurs in any detector used by SPECT. Two potential effects can occur:
1. Both pulses are counted as one (count lost)
2. The final pulse height detected is considered higher than either pulse ( i.e. the deviation in photon
energy)if the radioactive tracer is overestimated, it will cause an overestimation of the patient's GFR.thepill up effect should be prevented from happening.
The main cause of the pilt up effect is that the activity is too high (high counts), and a certain
radiation dose must be maintained in response to imaging requirements. Another method is toincrease the distance between the radiotracer and the detector.

Keywords

GFR pilt up effect

31

P-04
Korea
Radioimmunoassay Reagents Survey and Evaluation
Kim, Ji Na, Jae Seok An, Jeon, Young Woo, Yoon, Sang Hyuk, Kim, Yoon Cheol
National Cancer Center

When a new diagnostic test is introduced or reagent changes are made in a laboratory, acomprehensive and careful evaluation of the diagnostic procedure and reagents as well as
consideration of the cost of purchase and maintenance are necessary. We share our experience inperforming a comparative evaluation of radioimmunoassay reagents for all diagnostic procedures
used competitive bidding.
Twenty test procedures were evaluated, excluding consignment tests. Each reagent was examined
for the test method, incubation time and sample volume needed for the test. The primary selection
was made according to whether it was available in our laboratory under the above factors. The
secondary selected factors were based on the comparative evaluation which is consisted to the data
correlation test, sensitivity measurement, recovery rate measurement and dilution test.
The most problematic factors during the comparative evaluation was sample securing, sample
securing period and sample volume. Lack of dilution solution or standard zero material forsensitivity measurement or dilution tests was an addition limitation. Comparative evaluation for test
reagent changes require sufficient preparation time to secure a large number and volume of samples.
In addition, setting the total sample volume and reagent volume range required for comparativeevaluation based on a single test will reduce the burden of sample securing and test implementationfor each comparative evaluation.

Keywords

Primary selection, Secondary selection, Evaluation

32

P-05
Korea
The Effect of hemolysis sample on the result of nuclear medicine blood test
Jin Tae Kim
Ajou University Medical Center

Purpose, In many item of nuclear medicine blood tests, Hemolysis samples are defined as
inappropriate sample and are recommaended not to be used for blood test. So, the lab requires reblood collection in the blood collection room and is performing the test using the re-collected
normal sample. However, we have not studied the effect of hemolysis sample on nuclear medicine,so we have decide to examine them in this study.
Material and Methods, The kit manuals of 23 test items were reviewed to confirm whether
hemolysis samples were used. The subjects were 22 general applicants(male : 6, female : 13) andthe samples were collected by each two SST Tube. One was obtained by centrifugation normally,
the other was obtained hemolysis sample. SPSS19 program was used for staistical comparison of
the test resuls.
Results, There was no significant difference between normal serum and hemolsis serum in 21 of 23
test items, but the results of insulin and C-peptide were significantly lower(p<0.05).
Conclusion, Biochemical and gematological tests have a great effect on the results of the hemolysis
samples, but immunological tests are relatively low. Similarly, nuclear medicine tests using
ummunological methods represented that hemolysis did not affect the test results except for sometests. Therefore, it is thought that the demand for re-collection due to hemolysis will be reduced in
the laboratory, which will help improve the work process of the laboratory.

Keywords

Hemolysis, insulin, C-peptide

33

<< MEMO >>34

Board Members of ASNMT
JAPAN
Tomoaki Yamamoto
Hiroyuki Tsushima(Kyorin University)(Kobe Tokiwa University)

Kohei Hanaoka
Takeyuki Shibutani
Daisuke Hasegawa
Mitsuha Fukami(Kindai University)(Kanazawa University)(Kobe Tokiwa University)(Kyorin University)

KOREA
Hong-Jin Lee
Hong-Hae Lee
Hyun-Yeong Chang
Kyung-Jae Lee
Han-Kyung Seo
Jun-Young Park

(Seoul National University Hosptal)(Seoul National University Boramae Hospital)(Seoul National University Bundang Hospital)(JeonBuk University)(Yonsei University Health System severance Hospital)

TAIWANChen Hi-Ping(Landseed International Hospital)

Tu Kao-Yin
Yang Bang-Hung
Wang Xiu-Shen
Huang Yih-Hwen
Huang Pu-Rong(Mackay Memorial Hospital)(Taiwan Veterans Hospital)(Taichung Veterans General Hospital)(National Taiwan University Hospital)

35

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X 線 CT 組合せ型 SPECT 装置

Symbia Pro.specta

Modernize to
MAXIMIZE
モダナイズで核医学検査に最大限の outcome を

www.siemens-healthineers.com/jp
ビジュアル内で使用されている臨床画像及び科学的
画像はイメージです。特定個人のものではなく、また当社製品の使用により得られるものではありません。

X 線 CT 組合せ型 SPECT 装置 シンビアT6 ／ T16

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MI_Symbia_Prospecta_AD_A5Y_4C_221118.indd 1

2022/11/18 14:59

放射性医薬品／アミロイドイメージング剤

処方箋医薬品注） 保険未適用

放射性医薬品基準フロルベタピル（18F）注射液
注意－医師等の処方箋により使用すること。

注）※効能又は効果、用法及び用量、警告・禁忌を含む使用上の注意等の詳細については、電子添文をご参照ください。
アミヴィッド、AMYViDはAvid Radiopharmaceuticals, Inc. の登録商標です。

2022年3月改訂

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The 11th Asian Society of Nuclear Medicine Technology
発行：2023年11月18日

編

集：アジア核医学技術学会事務局（日本核医学技術学会内）〒530-0043 大阪市北区天満1丁目18-19-403
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