Last updated: 9:20 PM, 2/4/2023

Future Drug Discovery Empowered by Chemical Biology
Poster Presenters
PosterNumberName

Affiliation

Position

Poster Title

P-01

Aya Yoshimura

Department of Pharmaceutical Sciences, Hokkaido University

Assistant Professor

MeVIUS: a platform for unlocking silent secondary metabolites by bacterial membrane vesicles

P-02

Takuya Kamikawa

Graduate School of Science, Kyushu University

Graduate student

Development of synthetic molecule/protein hybrid probes for fluorogenic detection of methylated RNA

P-03

Kyungjae Myung

Institute for Basic Science

Director

Small molecule inhibitors leads to proteolysis of homologous recombination proteins resulting in cell death in PARP
inhibitor-resistant tumors

P-04

Junya Kakegawa

Pharmaceutical Frontier Research Laboratories, JT Pharma

Senior Research Scientist

Thermal proteome profiling reveals glutathione peroxidase 4 as the target of the autophagy inducer conophylline

P-05

Yuya Maruyama

Laboratory for Immune Homeostasis, RIKEN Center for Integrative
Medical Sciences

Graduate student

A pseudo-irreversible inhibition elicits a persistent efficacy of the sphigosine-1-phosphate receptor-1 antagonist

P-06

Yifan Huang

Hoshi University

Graduate Student

Design, Synthesis, and Evaluation of Trivalent PROTACs Having a Functionalization Site with Controlled Orientation

P-07

Yushi Futamura

RIKEN CSRS

Visiting Scientist

SAR and mode of action study on potent antimalarial compounds, lucilactaenes

P-08

Hiroyuki Hirano

Chemical Resource Development Research Unit, Technology Platform Division,
Technical Staff I
Center for Sustainable Resource Science RIKENIntroduction of RIKEN NPDepo and Collaborative Research

P-09

Hiroyuki Nakamura

Tokyo Institute of Technology, Institute of Innovative Research,
Laboratory for Chemistry and Life Science

Professor

Construction of sp3-rich three-dimensional tri- and tetracyclic scaffolds for drug discovery

P-10

Yuki Okura

Nagoya University

Undergraduate

Engineerimg natural products by Chem-Bio hybrid synthesis for drug discovery of dysentery amoebiasis

P-11

Sungoh Ahn

SPARK Biopharma

Senior manager

Novel Small Molecule to upregulate STING protein level by inhibiting TRIM29-mediated STING ubiquitination

P-12

Shohei Ebihara

Nagoya University

Undergraduate (B4)

Target identification and binding mode analysis using ligand-dissociation-type pyrene probes

P-13

Jae-Hoon Choi

Shizuoka University, Faculty of Agriculture

Associate Professor

Fairy Chemicals, New Plant Hormones, Biosynthesized in Novel Purine Metabolism

P-14

Ryu Hashimoto

Graduate School of Engineering, Osaka University

Graduate student

Efficient Visible/NIR Light-driven Uncaging of Hydroxylated Thiazole Orange-based Caged Compounds in Aqueous
Solution

P-15

Hiroki Kamo

Faculty of Science and Technology, Keio Univ.

Graduate student

Tyrosinase negatively regulates vasculogenic mimicry in human melanoma cells

P-16

JING WU

Shizuoka University, Faculty of Agriculture

Researcher“Fruiting liquid” of mushroom-forming fungi; Novel source of bioactive compounds –fruiting-body inducer, and HIF- andAxl- inhibitor–

P-17

Junhong Wang

Shizuoka University, Graduate School of Science and Technology

Ph. D. Student

Proof of the existence of novel hericenones in Yamabushitake (Lion's mane, Hericium erinaceus) in collaboration withsynthetic chemistryP-18

Mihaya Kotajima

Shizuoka University, Graduate School of Science and Technology

Graduate student

Biosynthetic studies on fairy chemicals in the fungus Lepista sordida

P-19

Kohei Toh

Kyoto University

Graduate student

Chemoproteomic Identification of Blue-Light-Damaged Proteins

P-20

Kazuki Miura

Laboratory for Chemistry and Life Science, Institute of Innovative
Research, Tokyo Institute of Technology

Assistant Professor

Development of intracellular molecular targeted photodynamic therapy as a novel photodynamic therapy strategy

P-21

Minami Nakajima

Department of Applied Chemistry,Faculty of Science andTechnology, Keio University

Graduate Student

Vasculogenic mimicry is inhibited by actin-modulating compounds in human breast cancer cells

P-22

Ai Koyama

Graduate School of Pharmaceutical Sciences, Kyoto University

Undergraduate student, Prof.
Hideaki Kakeya’s Group

Acyl sulfonamide-mediated amidation for biomimetic peptide synthesis

P-23

YuKai Sun

Graduate school of pharmaceutical sciences, Kyoto University

Graduate Student

Synthetic study on 2-(1H-imidazol-4-yl)-1,3,4-oxadiazole scaffolds for drug discovery

P-24

Shun Saito

Keio University, Department of Biosciences and Informatics

Assistant Professor, Prof. Midori
Chemical biology of heat shock metabolites (HSM) produced by Streptomyces species
Arai’s GroupLast updated: 9:20 PM, 2/4/2023

P-25

Takafumi Kasai

Graduate School of Pharmaceutical Sciences The University ofTokyo

Master Student

Highly sensitive far-red to near-infrared fluorescence probe for hypoxia to detect at oxygen concentrations around 1%and below.

P-26Yukiko Ujie

Keio University, Faculty of Science and Technology, Department ofBiosciences and Informatics

Ph.D. Student, Prof. Midori
Arai’s GroupCo-culture of pathogenic fungi Aspergillus species and immune cells for activating silent genes

P-27

Tasuku Hirayama

Gifu Pharmaceutical University

Associate Professor

Live-cell imaging of labile heme by a novel heme-selective fluorescent probe

P-28

Taka Sawazaki

School of Pharmaceutical Sciences, Wakayama Medical University

assistant professor

Catalysis driven by amyloid-substrate complex (CASL)

P-29

Takefumi Kuranaga

Graduate School of Pharmaceutical Sciences, Kyoto University

Specially Appointed Associate
Professor

Reactivity-guided identification and total synthesis of an unstable anticancer macrolide presaccharothriolide Z

P-30

Xintong Liu

Chemical Resource Development Research Unit, RIKEN CSRS

Student

Establishment of High-throughput screening system for ligands of β-TrCP and analyses of the hit compounds.

P-31

Hiroaki Ikeda

Kyoto University, Graduate School of Pharmaceutical Sciences

Postdoctoral researcher, Prof.
Hideaki Kakeya's Group

Screening for anticancer lead compounds through a new strategy for targeting cancer stem cells

P-32

Yanjun Pan

Kyoto University, Graduate School of Pharmaceutical Sciences

Ph.D. Student, Prof. Hideaki
Kakeya's Group

Chemical biology research on an asparagine synthetase (ASNS) inhibitor as a molecular-targeted anticancer drug

P-33

Mieko TsujiGifu Pharmaceutical University, Department of PharmaceuticalScience, Prof. Hideko Nagasawa’s Group

Assistant Professor

Development of photocaged peroxides for the control of oxidative stress in mitochondria

P-34

Takanori Matsumaru

Faculty of Science and Technology, Keio University

Assistant Professor

Innate immune receptor Mincle ligands: Synthesis and biological functions

P-35

Ryosuke Tanaya

University of Toyama

Graduate student

Creation of molecular diversity by CsPT4, an aromatic prenyltransferase from Cannabis sativa

P-36

Kodai Sueyoshi

Faculty of Science and Technology, Keio University

Graduate Student

Biofunctional evaluation of α-GalCer derivatives with modified lipid moieties: CD1d-ligand complex stability studies

P-37

Hiroyuki Uno

Graduate School of Advanced Science and Engineering, Waseda
University / RIKEN Center for Sustainable Resource Science

Graduate Student

Construction of AI-based screening system for antifungal substances based on morphological changes of Aspergillus
oryzaeP-38

Nobumoto WATANABE

Chemical Resource Development Research Unit, RIKEN CSRS

Temporary EmployeeRole of c-Myc protein on the cytotoxicity of antimycin A in cancer cells

P-39

Tatsuki Nonomura

Graduate School of Engineering, Osaka University

Graduate student

Development of an optical transcription regulation system using a caging-group free photoactivatable dye

P-40

Bengang XING

Nanyang Technological University

Professor

Rational Design of Tumor Hypoxic Enzyme Derived Clicking Proteolysis-targeting Chimeras for Targeted Epigenetic
Deactivation

P-41

Asmaa Mostafa Abdelbari
Soliman Farrag

Kyoto University, Graduate school of Medicine, Chemical Biology
department

Graduate student

Real-Time Visualization of Cellular Phase-Separating Proteins

P-42

Takaya Minami

Graduate School of Science and Technology, Keio University

Graduate Student

Synthetic studies for funiculosin and its immunomodulatory analogues

P-43

Shunya Kikuchi

Keio University

Graduate Student

Synthetic studies for analysis of peptide-lipid antigen presentation

P-44

Hideaki Kakeya

Graduate School of Pharmaceutical Sciences, Kyoto University

Professor

Pharmacologic characterization of TBP1901, an innovative prodrug form of curcumin, and CRISPR-Cas9 screen fortherapeutic targets of curcumin

P-45

Makoto Muroi

Technology Platform Division, RIKEN Center for Sustainable
Resource ScienceSenior Research Scientist

Proteomics-based target identification system for biological active compounds, ChemProteoBase and 2DE-CETSA

P-46

Ren Ito

The University of Tokyo

Graduate Student

Fluorescence imaging of LAT1-expressing cancer cells using Click chemistry

P-47

Manchir Tserendagva

Kyoto University, Graduate School of Medicine

Graduate Student /M2/,
Prof.Uesugi's group

Regulation of SREBP Signaling by TMEM43

P-48

Myat Nyein Khine

Tokyo University of Agriculture and Technology

PhD student

Binding interaction analysis of anticancer saponin OSW-1

P-49

Kazunari Ueki

Graduate School of Science and Technology, Keio University

Ph. D. Student

Synthesis and immunomodulation of monoglycosphingolipids

P-50

Kota Noritsugu

Tokyo University of Pharmacy and Life Sciences

Project Researcher

Lysine long-chain fatty acylation regulates TEAD transcription factors in Hippo signaling pathway