November 7th, Saturday, ~ November 21st, Saturday
Keynote Lecture(Video On-demand distribution)KL

Porphyromonas gingivalis interactions with epithelial cells in the community context
Dr. Richard J Lamont(Department Oral Immunology & Infectious Diseases, University of Louisville, School of Dentistry)

Greeting from IADR President(Video On-demand distribution)
G
Dr. Pamela Den Besten(Department of Orofacial Sciences, School of Dentistry, University of California San Francisco)Special Lecture(Video On-demand distribution)
SL

Tubular Dentin Regeneration and Its Clinical Application
Dr. Joo-Cheol Park
(Laboratory for the Study of Regenerative Dental Medicine, Department Oral Histology-Developmental
Biology, School of Dentistry, Seoul National University)

Symposium Ⅰ~Ⅲ, Rising Scientist Session(Lecture;Video On-demand distribution / Q & A;Live streaming)

─7─

November 7th, Saturday
10:00-12:00 Symposium I“At the front-line: Etiology of periodontitis”

SⅠ-1

SⅠ-2

SⅠ-3

SⅠ-4

Moderator: Dr. Kazuyuki Ishihara(Department of Microbiology, Tokyo Dental College, Tokyo, Japan)
Moderator: Dr. Yoshihisa Yamashita(Section of Preventive and Public Health Dentistry, Division of Oral Health,Growth and Development, Faculty of Dental Science, Kyushu University, Fukuoka, Japan)
Bacterial composition of overall oral microbiota associated with periodontal disease and health.
Dr. Toru Takeshita(Section of Preventive and Public Health Dentistry, Faculty of Dental Science, Kyushu University)
The significant role of Porphyromonas gingivalis “Gingipains” as a virulence factor on periodontal
inflammation
Dr. Masaaki Nakayama1, Dr. Naoya Ohara2(1Department of Microbiology, Graduate school of Medicine, Dentistry and Pharmaceutical Sciences,
Okayama University, 2Advanced Research Center for Oral and Craniofacial Sciences (ARCOCS),
Dental School, Okayama University)
Periodontitis as an “osteoimmune” disease
Dr. Masayuki Tsukazaki(Department of Immunology, Graduate School of Medicine and Faculty of Medicine,
The University of Tokyo)
Epithelial barrier breakdown by Porphyromonas gingivalis
Dr. Atsuo Amano, Dr. Hiroki Takeuchi(Department of Preventive Dentistry, Graduate School of Dentistry, Osaka University)

13:00-14:30 Rising Scientist Session“Neuroscience”
Moderator: Dr. Tazuko Goto
(Department of Oral and Maxillofacial Radiology, Tokyo Dental College, Tokyo, Japan)
RS-1 Factors secreted from dental pulp stem cells show multifaceted benefits for Synergistically
Regenerate Transected Rat Peripheral Nerves by Altering Macrophage Polarity.
Dr. Fumiya Kano
(Department of Tissue regeneration Institute of Biomedical Sciences, Tokushima University Graduate
School)RS-2 Phenotypic and neuroplastic changes in trigeminal nociceptive pathways following trigeminal nerve
injuryDr. Ayano Katagiri(Department of Oral Physiology, Osaka University Graduate School of Dentistry, Suita, Japan)
RS-3 The human brain and mastication; broad impact on systemic functions
Dr. Jun Miyamoto

─8─

(Department of Maxillofacial Orthognathics, Graduate School of Medical and Dental Sciences,
Tokyo Medical and Dental University (TMDU))

─9─

November 8th, Sunday
10:00-12:30 SymposiumⅡ“Future is now! Stem cell revolution in hard and soft tissue engineering”
Moderator: Dr. Toshifumi Azuma(Department of Biochemistry, Tokyo Dental College, Tokyo, Japan)
Moderator: Dr. Shinsuke Oba(Department of Cell Biology, Institute of Biomedical Sciences, Nagasaki University)
SⅡ-1 Generation of skeletal cells from pluripotent stem cells
Dr. Shinsuke Oba(Department of Cell Biology, Institute of Biomedical Sciences, Nagasaki University)
SⅡ-2 Establishment of an in vitro culture system for tenogenic/ligamentogenic differentiation using
ScxGFP iPS cells
Dr. Chisa Shukunami(Department of Molecular Biology and Biochemistry, Graduate School of Biomedical and Health Sciences,
Hiroshima University)
SⅡ-3 Classification and pathological mechanisms of Craniosynostosis based on the differentiation patternof iPS cells
Dr. Sachiko Iseki(Section of Molecular Craniofacial Embryology, Tokyo Medical & Dental University Graduate School of
Medical and Dental Sciences)
SⅡ-4 Molecular mechanisms of craniosynostosis in Apert syndrome.
Dr. Takashi Nakamura1, Dr. Hiroyuki Ogura2(1Department of Biochemistry/Research Branding Project, Tokyo Dental College.,
Department of Orthodontics, Tokyo Dental College.,2
Department of Biochemistry/Oral Health Science Center/Research Branding Project, Tokyo Dental
College.)
SⅡ-5 Application of iPS cell technologies to treat skeletal disease
Dr. Akihiro Yamashita, Dr. Noriyuki Tsumaki(Centre for iPS cell Research and Application (CiRA), Kyoto University, Japan)

13:00-15:00 Symposium Ⅲ“Pathophysiological approach from oral function to systemic diseases”
Moderator: Dr. Yoshiyuki Shibukawa(Department of Physiology, Tokyo Dental College, , Tokyo, Japan)
Moderator: Dr. Naofumi Uesaka(Department of Cognitive Neurobiology, Graduate School of Medical and Dental Sciences,
Tokyo Medical and Dental University, Tokyo, Japan)
SⅢ-1 Taste renin-angiotensin system may contribute to the maintenance of sodium homeostasis.
Dr. Noriatsu Shigemura(Section of Oral Neuroscience, Graduate School of Dental Science, Kyushu University,,
Research and Development Center for Five-Sense Devices, Kyushu University.)
SⅢ-2 Pathophysiology of SB: challenges from human and animal studies

─ 10 ─

Dr. Takafumi Kato
(Osaka University Graduate School of Dentistry, Department of Oral Physiology)
SⅢ-3 Common pathophysiological features in burning mouth syndrome and irritable bowel syndrome
Dr. Masamichi Shinoda(Department of Physiology, Nihon University School of Dentistry)
SⅢ-4 In vivo Dynamics of Dental Tissue Regeneration
Dr. Toshihide Mizoguchi(Oral Health Science Center, Tokyo Dental College, Tokyo, Japan)

─ 11 ─

Poster Presentation
Dental Materials 1: Ceramic-based Materials
001: Wear Resistance of Novel Machinable Glass Ceramics
S. Kariya, T. Azuma, F. Fusejima
R&D Dept., GC Corporation, Tokyo, JAPANDental Materials 4: Adhesion
002: Evaluation of bonding layer durability on 2-step self-etch adhesive
K. FUJIMORI, K. HIRANO, F. FUSEJIMARESEARCH & DEVELOPMENT, GC CORPORATION, TOKYO, Japan

003: Bonding properties of acrylic resin to zirconia and polyaryletherketone (PAEK)

T.-Y. PENG1, S. SHIMOE2, D.-J. LIN1, M. KAKU2School of Dentistry, College of Dentistry, China Medical University, Taiwan R.O.C, 2Departmentof Anatomy and Functional Restorations, Hiroshima University Graduate School of Biomedical &Health Sciences, Hiroshima, Japan
1004: Bond strength between one-step adhesives and dentin after cyclic loading

T. EGOSHI1, Y. TAIRA1, K. SOENO2, K. KAIDA1, S. KUBO1, H. MURATA3
Division of Cariology and Restrative Dentistry, Department of Prosthetic Dentistry, Nagasaki
University, Nagasaki, Japan, 2Department of Appried Prosthodontics, Nagasaki University, Nagasaki,
Japan, 3Department of Prosthetic Dentistry, Nagasaki University, Nagasaki, Japan

1005: Influence of saliva contamination on adhesion performance of adhesive resin cement
S. MURAKAMI, K. HIRANO, F. FUSEJIMARESEARCH & DEVELOPMENT, GC CORPORATION, TOKYO, Japan.

Cariology Research-Demineralization/Remineralization
006: Evaluation of Dentin Anti-Demineralization potential of S-PRG Containing SelfAdhesive Resin Cement

S. ThanNaing1, N. Hiraishi1, A. Abdou1,3, J. Tagami1
Cariology and Operative Department, Tokyo Medical and Dental University, Tokyo, JAPAN,
2
Department of Conservative Dentistry, University of Dental Medicine Mandalay, Mandalay,
Chanmyathazi, MYANMAR, 3Biomaterials Department, Faculty of Dentistry, Modern University forTechnology and Information, Cairo, EGYPT
1

007: Preparation of Filler-Dispersed Resin Composite for Additive Manufacturing

P. KARNTIANG1, H. IKEDA2, Y. NAGAMATSU2, H. SHIMIZU2
1
Division of Operative Dentistry, College of Dentistry, Rangsit University, Pathum Thani, Thailand,
2
Division of Biomaterials, Department of Oral Functions, Kyushu Dental University.

008: Enamel Remineralization of TCP with Fluoride in Toothpaste: EPMA Study

H. HAMBA, H. ISHIZUKA, Y. MIYAYOSHI, K. NAKAMURA, T. MURAMATSU
Department of Operative Dentistry, Cariology and Pulp Biology, Tokyo Dental College, Tokyo, Japan─ 12 ─

009: EVALUATION OF THE EFFECT OF ZINC-CONTAINING ORAL MATERIALSON REMINERALIZATION USING IN-AIR MICROBEAM PIXE/PIGE
M. Sakurai1, Y. Matsuda2, K. Okuyama3, H. Yamamoto2, M. Hayashi2, T. Saito1
Division of Clinical Cariology and Endodontology, Department of Oral Rehabilitation, Health
Sciences University of Hokkaido, Tobetsu-cho, Ishikari-gun, Hokkaido, JAPAN, 2Department ofRestorative Dentistry and Endodontology, Osaka University Graduate School of Dentistry, Osaka,
JAPAN, 3Department of Dental Materials Science, Asahi University School of Dentistry, Mizuho,
Gifu, JAPAN1

Cariology Research-Fluoride & Ca-based Products
010: Dynamics of Ions Artificially Introduced into Caries-affected Dentin

K. NAITO1, H. YAMAMOTO1, Y. MATSUDA2, K. OKUYAMA3, M. HAYASHI1
1
Department of Restrative Dentistry and Endodontology, Osaka University Graduate School of
Dentistry, 2Division of Clinical Cariology and Endodontology, Department of Oral Rehabilitation,
School of Dentistry, Health Sciences University of Hokkaido, 3Department of Dental Materials
Science, Division of Oral Functional Sciences and Rehabilitation, Asahi University School of
Dentistry

Dental Materials 2: Polymer-based Materials
011: Physical properties of Resorbable P(LA/CL) bilayer membrane for GBR
Y. SAKAGUCHI, E. ARIMA, K. YAMANAKA, F. FUSEJIMAGC Corporation, Tokyo, Japan

Prosthodontics Research
012: Influence of Molding Angle on 3D-printed Partial Denture Framework

H. KOBAYASHI1, A. TASAKA1, T. SHIMIZU1, S. HIGUCHI2, S. YAMASHITA1
1
Department of Removable Partial Prosthodontics, Tokyo Dental College, 2Wada Precision Dental
Laboratories Corporation

Oral Health Research013: Microbicidal effect and storage stability of neutral electrolyzed water-based gels

Y. NAGAMATSU1, H. NAGAMATSU2, H. IKEDA1, H. SHIMIZU1Division of Biomaterials, Department of Oral Functions, Kyushu Dental University, Fukuoka, Japan,
2
Division of Comprehensive Dentistry, Department of Oral Functions, Kyushu Dental University,
Fukuoka, Japan

1

014: A pilot study of effects on Dentifrice Containing Neem for Oral Malodor, PlaqueAdhesion, Gingival Inflammation and Oral Bacteria

M. YASUI, K. SHINADA
Department of Priventive Oral Health Care Sciences, Tokyo Medical and Dental University, Tokyo,
Japan

Microbiology/Immunology
015: Antimicrobial effects and mechanical properties of acrylic resin containing aPIZAS

K. INABA1, H. WATANABE1, Y. WADA1, S. WATANABE1, H. SASAKI1, H. HIRAMINE2, M.
SASAKI3, T. NIHEI1, N. HAMADA1
1
Department of Oral Science, Kanagawa Dental University, Yokosuka, Japan, 2Department of Highly─ 13 ─

Advanced Stomatology, Yokohama Clinical Education Center of Kanagawa Dental University,
3
Nissho Chemistry Corporation

016: Effects of S-PRG eluate on bacterial properties related to oral malodor

S. OMAGARI1, M. YONEDA1, N. SUZUKI2, D. GRENIER3, S. YAMAMOTO1, K. YAMADA1, J.
HATAKEYAMA1, H. MORITA4, C. KOGA5, T. HIROFUJI1
1
Section of General Dentistry, Department of General Dentistry, Fukuoka Dental College, Fukuoka,
Japan, 2Section of Oral Public Health, Department of Preventive and Public Health, Fukuoka Dental
College Fukuoka, Japan, 3Groupe de Recherche en Ecologie Buccale, Faculte de medecine dentaire,
Universite Laval, Quebec, Canada, 4The Center for Visiting Dental Service, Department of General
Dentistry, Fukuoka Dental College, Fukuoka, Japan, 5Center for Oral Diseases, Fukuoka Dental
College Fukuoka, Japan

017: Evaluation of anti-biofilm effects of bio-active GIC using a bioreactor

T. KOHNO, Y. LIU, F. DENG, R. TSUBOI, H. KITAGAWA, S. IMAZATO
Department of Biomaterials Science, Osaka University Graduate School of Dentistry, Suita, Japan

018: Streptococcus mutans inhibition by toothbrush monofilament with surface prereacted glass-ionomer
S. MATAYOSHI, T. KITAMURA, M. OTSUGU, R. NOMURA, K. NAKANO
Department of Pediatric Dentistry, Osaka University Graduate School of Dentistry, Japan

019: Comparison of microbiome organized on denture base materials and hydroxyapatite
Y. NEZU1, M. RYU1, K. ISHIHARA2, T. UEDA1
1
Removable Prosthodontics & Gerodontology, Tokyo Dental College, Tokyo, Japan, 2Microbiology,
Tokyo Dental College

Cariology Research-Microbiological Studies/Biofilm
020: ABC transporter activities in biofilm formation by Streptococcus mutans

K. GOTO, M. MATSUMOTO-NAKANO
Department of Pediatric Dentistry, Okayama University Graduate School of Medicine, Dentistry andPharmaceutical Sciences, Okayama, Japan

Microbiology/Immunology
021: Inhibitory Effect of Cyclodextran on Glucosyltransferase B in Streptococcus mutans

H. ASAUMI, K. GOTO, M. MATSUMOTO-NAKANO
Department of Pediatric Dentistry, Okayama University Graduate School of Medicine, Dentistry andPharmaceutical Sciences, Okayama, Japan

022: The effects of fatty acid salts against Streptococcus mutans biofilm

A. KURAHASHI, K. WATANABE, T. SATO, K. INABA, H. SASAKI, N. HAMADA
Department of Oral Science, Graduate School, Kanagawa Dental University

023: Evaluation of collagen-binding properties of killed Streptococcus mutans strains

Y. SUEHIRO, S. MATAYOSHI, M. OTSUGU, R. NOMURA, K. NAKANO
Department of Pediatric Dentistry, Osaka University Graduate School of Dentistry, Osaka, Japan

024: Screening of S. salivarius isolates with anti-caries activities

H. NAKADE1, S. ALI2, D. DUFOUR2, C. LEVESQUE2, S. GONG2Faculty of Dentistry, Tokyo Medical and Dental University, 2Faculty of Dentistry, University ofToronto1

─ 14 ─

025: Characteristics of anti-periodontal bacterial activity in culture supernatant ofprobiotic

T. KAWAI1, R. SHIN2, Y. ITO2, S. IKAWA3, T. TANAKA3, T. OHSHIMA1
1
Department of Oral Microbiology, Tsurumi University School of Dental Medicine, Kanagawa, Japan,
2
ALA Research Institute for Fermentative Microbes, Tokyo, Japan, 3Technology Research Institute of
Osaka Prefecture, Osaka, Japan

Periodontal Research-Pathogenesis
026: Exploring for prevention of periodontal disease using products of the probiotic
bacteria, genus Lactobacillus -Targeting the genus PorphyromonasY. SAKAI, T. OHSHIMA, T. KAWAI
Tsurumi University Faculty of Dentistry Department of Dentistry

Microbiology/Immunology
027: Gemella haemolysans specifically inhibits the growth of Porphyromonas gingivalis

T. MIYOSHI1, N. YOSHINARI2, A. YOSHIDA1
1
Department of Oral Microbiology, Matsumoto Dental University, Nagano, Japan, 2Department of
Periodontology, Matsumoto Dental University, Nagano, Japan

028: Fusobacterium nucleatum metabolically integrates commensals and pathogens in oral
biofilms
A. SAKANAKA1, M. KUBONIWA1, S. SHIMMA2, S. MAYUMI1, R. LAMONT3, E. FUKUSAKI2, A.
AMANO1
1
Department of Preventive Dentistry, Osaka University Graduate School of Dentistry, Osaka, Japan,
2
Department of Biotechnology, Osaka University Graduate School of Engineering, Osaka, Japan,
3
Department of Oral Immunology and Infectious Diseases, School of Dentistry, University ofLouisville, Louisville, KY, USA

029: Analysis of novel genotypes of Mfa1 fimbriae in Porphyromonas gingivalis

K. SAKAE1, K. NAGANO2, Y. HASEGAWA1
1
Department of Microbiology, School of Dentistry, Aichi Gakuin University, Aichi, Japan,
2
Department of Microbiology, School of Dentistry, Health Sciences University of Hokkaido,
Hokkaido, Japan

030: Role of hyalin-like protein in biofilm formation by Capnocytophaga ochracea

T. WARITA1, K. SHIBAYAMA1, E. KOKUBU1, D. KITA2, Y. KIKUCHI1, K. ISHIHARA1
Department of Microbiology, Tokyo Dental College, Tokyo, Japan, 2Department of Periodontology,
Tokyo Dental College, Tokyo, Japan

1

031: The periodontopathic bacterium Fusobacterium nucleatum induced
proinflammatory cytokine production by human respiratory epithelial cells and in
the lower respiratory organs in mice

K. IMAI1, N. WATANABE1,2, S. YOKOE1,2, S. SATO2
Department of Microbiology, Nihon University School of Dentistry, 2Department of Periodontology,
Nihon University School of Dentistry1032: IgA Nephropathy-like Lesion Development in Rat Caries Model

S. NAKA1, K. WATO2, T. MISAKI3, Y. NAGASAWA4, S. ITO5, R. NOMURA2, M. MATSUMOTONAKANO1, K. NAKANO2
1
Department of Pediatric Dentistry, Okayama University Graduate School of Medicine, Dentistry─ 15 ─

and Pharmaceutical Sciences, Okayama, Japan, 2Department of Pediatric Dentistry, Division of Oral
Infection and Disease Control, Osaka University Graduate School of Dentistry, Suita, Oska, Japan,
3
Division of Nephrology, Seirei Hamamatsu General Hospital, Hamamatsu, Japan, 4Division of
Kidney and Dialysis, Department of Internal Medicine, Hyogo College of Medicine, Nishinomiya,
Japan, 5Department of Nephrology anf Endocrinology, National Defense Medical College,
Tokorozawa, Japan

033: Effects of Helicobacter pylori Infection in Caries-induced Rats

T. KADOTA, Y. OGAYA, R. NOMURA, K. NAKANO
Department of Pediatric Dentistry, Osaka University Graduate School of Dentistry, Osaka, Japan

034: Prevalence of Specific Streptococcus mutans Harbored by Non-alcoholic
Steatohepatitis Patients

K. TABATA1, S. NAKA1, S. TONOMURA2,3,4, K. NAKANO5, M. MATSUMOTO-NAKANO1
1
Department of Pediatric Dentistry, Okayama University Graduate School of Medicine, Dentistry andPharmaceutical Sciences, Japan, 2Department of Neurology, Nara City Hospital, Japan, 3Departmentof Neurology, National Cerebral and Cardiovascular Center, Japan, 4Department of Neurology,
Graduate School of Medicine and Faculty of Medicine, Kyoto University, Japan, 5Department ofPediatric Dentistry, Division of Oral Infection and Disease Control, Osaka University Graduate
School of Dentistry, Suita, Osaka, Japan

Pediatric Oral Health Research035: The Initiation and development of oral microbiome formation in Japanese healthy
infants
A. SAKURAI, H. HOMMA, N. NAGAI, T. OTA, S. SHINTANI
Department of Pediatric Dentistry, Tokyo Dental College, Tokyo, Japan

Periodontal Research-Pathogenesis036: Omics analysis defines differences in microbial community structure between periimplantitis and periodontitis

K. KOMATSU1, Y. TAKEUCHI1, T. SHIBA1, T. WATANABE2, M. SHIMOGISHI3, M.
SHIBASAKI3, T. NEMOTO1, T. KOYANAGI1, S. KATAGIRI1, T. IWATA1
1
Department of Periodontology, Graduate School of Medical and Dental Sciences, Tokyo Medical and
Dental University, Tokyo, Japan, 2Department of Chemistry, Nihon University School of Dentistry,
Tokyo, Japan, 3Department of Oral Implantology and Regenerative Dental Medicine, Tokyo Medical
and Dental University, Tokyo, Japan

037: Periodontal Bacteria Distribution in Child with Early Primary Tooth Loss

Y. MIYAI, S. NAKA, M. MATSUMOTO-NAKANOOkayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama,Japan

Periodontal Research-Therapy
038: CTLA-4 Reduces Bone Resorption Through the Inhibition of Osteoclast
Differentiation

S. NAKANE1, K. IMAMURA1, K. ISHIHARA2,3, A. SAITO1,2
1
Department of Periodontology, Tokyo Dental College, Tokyo, Japan, 2Oral Health Science Center,
Tokyo Dental College, Tokyo, Japan, 3Department of Microbiology, Tokyo Dental College, Tokyo,Japan─ 16 ─

Periodontal Research-Pathogenesis039: An immunohistochemical study on the expression of bioactive molecules in the mouse
kidney in P. gingivalis LPS-induced diabetic nephropathy
K. KOICHIRO1, Y. SAWA2, T. FUJITA1, S. TAMAOKI1
Section of orthodontics Department of Oral Growth & Development, Division of Clinical Dentistry,
Fukuoka Dental College, 2Deparment of Oral Function & Anatomy, Okayama University Graduate
School of Medicine, Dentistry, and Pharmaceutical Sciences
1

Oral Medicine & Pathology Research
040: Artepillin C regulates extracellular matrix gene expressions in human periodontal
fibroblasts by DNA methylation

R. TAKAI1, O. UEHARA2, T. MORIKAWA3, K. YOSHIDA3, J. SATO3, Y. ABIKO3, T. OHTA1
1
Advanced Research Promotion Center, Health Sciences University of Hokkaido, Hokkaido, Japan,
2
Division of Disease Control and Molecular Epidemiology, Health Sciences University of Hokkaido,
Hokkaido, Japan, 3Division of Oral Medicine and Pathology, Health Sciences University of Hokkaido,
Hokkaido, Japan

Periodontal Research-Pathogenesis
041: Exosomes from human gingiva-derived MSCs inhibit periodontal bone loss

Y. NAKAO, T. FUKUDA, Y. WATANABE, C. HAYASHI, K. KAWAKAMI, M. TOYODA, H.
YAMATO, T. SINJO, U. TANAKA, T. SANUI, F. NISHIMURA
Department of Periodontology, Division of Oral Rehabilitation, Faculty of Dental Science, Kyushu
University, Fukuoka, Japan

042: PPARγ is required for periodontal ligament cells to retain cemento/osteogeneity

H. YUAN1, S. SUZUKI1, A. SATO1, T. YAMAMOTO1, E. NEMOTO1, M. SAITO2, S. YAMADA1
1
The Department of Periodontology and Endodontology, Tohoku University school of Dentistry, 2The
Department of Operative Dentistry, Tohoku University school of Dentistry

Oral Medicine & Pathology Research043: Role of IQGAP1- Flightless I interaction in collagen remodeling by fibroblast

K. NAKAJIMA1, P. ARORA2, C. MCCULLOCH2
1
Department of Pathology, Tokyo Dental College, Tokyo, Japan, 2Faculty of Dentistry, University ofToronto, Toronto, ON, Canada

Periodontal Research-Therapy
044: Amelogenin down-regulates MHC class II antigen presentation on macrophages.

K. YOTSUMOTO, T. SANUI, H. YAMATO, U. TANAKA, Y. NAKAO, Y. WATANABE, C.
HAYASHI, T. FUKUDA, F. NISHIMURA
Department of Periodontology, Division of Oral Rehabilitation, Faculty of Dental Science, Kyushu
University, Fukuoka, Japan

Periodontal Research-Pathogenesis
045: Adipose specific C-C motif chemokine ligand (CCL) 19 overexpression drives themice to both insulin resistance and weight gain.

M. HAYASHI, M. IWASHITA, Y. NISHIMURA, T. SHINJO, T. ZEZE, T. SANO, A. YAMASHITA, F.

─ 17 ─

NISHIMURA
Department of Periodontology, Division of Oral Rehabilitation, Faculty of Dental Science, Kyushu
University

Periodontal Research-Therapy
046: Characterization of the PLAP-1-GFP/CreER knock-in mouse

T. IWAYAMA1, K. TOMITA1, S. MATSUMOTO1, M. IWASHITA1, C. FUJIHARA1, M.
TAKEDACHI1, S. YAMADA2, S. MURAKAMI1
1
Department of Periodontology, Osaka University Graduate School of Dentistry, Suita, Osaka, Japan,
2
Department of Periodontology and Endodontology, Tohoku University Graduate School of Dentistry,
Sendai, Miyagi, Japan

Implantology Research
047: Salivary Alpha-Amylase as a stress marker during dental implant surgeries
A. A. Sabbagh, H. Nakata, A. Abdou, K. Shohei, S. Kuroda
Tokyo medical and Dental University, Tokyo, JAPAN

Oral Medicine & Pathology Research
048: Regional differences in the density of Langerhans cells, CD8-positive T lymphocytes
and CD68-positive macrophages
Y. OMINE
Iryouhoujin Syuuyuu-kai, Tsuchiura, Japan

Periodontal Research-Pathogenesis
049: Delayed Wound Healing after Tooth Extraction under Malnutrition

Y. ZHANG1, H. IDEGUCHI1, H. AOYAGI1, K. YAMASHIRO1, T. YAMAMOTO1, M. NISHIBORI2,
S. TAKASHIBA1
1
Department of Pathophysiology - Periodontal Science, Okayama University Graduate School of
Medicine, Dentistry and Pharmaceutical Science, Okayama, Japan, 2Department of Pharmacology,
Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Science, Okayama,Japan

Oral & Maxillofacial Surgery Research
050: Assessment of Facial Changes after Orthognathic Surgery Using GeometricMorphometrics

S. AL BOUGHA1, H. NAKANO2, K. YASUDA1, T. YAMADA1, I. TAKAHASHI3, Y. MORI1
1
Section of Oral and Maxillofacial Surgery-Division of Maxillofacial Diagnostic and Surgical Science- Faculty of Dental Science, Kyushu University, 2Department of Dentistry and Oral Surgery, Divisionof Medicine for Function and Morphology of Sensory Organs, Faculty of Medicine, Osaka Medical
College, 3Department of Orthodontics, Faculty of Dental Science, Kyushu University

051: Metformin inhibits oral cancer cell growth by altering glucose metabolism

S. LIU1, J. WASHIO1, N. TAKAHASHI1
Division of Oral Ecology and Biochemistry, Department of Oral Biology, Tohoku University
Graduate School of Dentistry, Sendai, Japan, 2Department of Head and Neck Oncology, West China
Hospital of Stomatology Sichuan University, Chengdu, China

1

─ 18 ─

Oral Medicine & Pathology Research052: Sirtuin1 DNA hypermethylation may be a biomarker for malignant transformation
S. ISLAM, O. UEHARA, H. MATSUOKA, Y. ABIKO, I. CHIBA
Health Sciences University of Hokkaido

053: Role of EGFR-mediated MOB1 phosphorylation on Hippo pathway regulation
T. ANDO
Center of oral clinical examination, Hiroshima Univeresity Hospital, Hiroshima, Japan

054: Sema3A-AKT Axis In Salivary Gland And Adenoid Cystic Carcinoma Developments
T. FUJIMOTO1, S. FUJII2, T. KIYOSHIMA2
1
School of Dentistry, Kyushu University, 2Laboratory of Oral Pathology, Division of Maxillofacial
Diagnostic and Surgical Sciences, Faculty of Dental Science, Kyushu University

Oral & Maxillofacial Surgery Research
055: Effect of Ethinyl Estradiol on Mandibular Condyle of Female Rats

S. YAKLAI, R. PECHAYCO, Y. ABE, A. TAKIZAWA, I. MIZOGUCHI, T. TAKAHASHI, M.
CHIBA
Graduate School of Dentistry, Tohoku University

Craniofacial Biology Research
056: Histone methyltransferase SETDB1 negatively regulates PTH/PTHrP receptor inchondrocytes

P. THIHA, N. HIGASHIHORI, S. KANO, K. MORIYAMA
Department of Maxillofacial Orthognathics, Graduate School of Medical and Dental Sciences, Tokyo
Medical and Dental University

Stem Cell Biology Research
057: Generating MSC Spheroids Recovers Stemness Characteristics for Cortical Bone
Formation
Y. OHORI, K. NIIBE, H. EGUSADivision of Molecular and Regenerative Prosthodontics, Tohoku University Graduate School of
Dentistry, Sendai, Miyagi, Japan

Craniofacial Biology Research
058: The bHLH transcription factor HAND1 is involved in cortical bone volume throughthe regulation of collagen expression
N. FUNATO1, Y. TAGA3, L. E. LAURIE1, C. TOMETSUKA3, M. KUSUBATA3, K. OGAWAGOTO3
1
Department of Signal Gene Regulation, Tokyo Medical and Dental University, Tokyo, Japan,
2
Research Core, Tokyo Medical and Dental University, Tokyo, Japan, 3Nippi Research Institute of
Biomatrix, Ibaraki, Japan─ 19 ─

Mineralized Tissue059: Oxygen tension-dependent expression of monocarboxylate transpoter-1 is aprerequisite event for oxidative death of chondrogenic ATDC5 cells induced byinterleukin-1β.

M. TANAKA1, Y. MIYAMOTO1, K. YOSHIMURA1, K. SASA1, K. IKEZAKI1,2, T. SHIROTA2, R.
KAMIJO1
1
Department of Biochemistry, Showa University School of Dentistry, Tokyo, Japan, 2Department ofOral and Maxillofacial Surgery, Showa University School of Dentistry, Tokyo, Japan

Pediatric Oral Health Research
060: Effects of Anticancer Drugs on Mouse Tooth Germ Development

Y. TSUNODA1, S. NAKA1, R. OKAWA2, K. NAKANO2, M. MATSUMOTO-NAKANO1
Department of Pediatric Dentistry, Okayama University Graduate School of Medicine, Dentistry andPharmaceutical Sciences, Japan, 2Department of Pediatric Dentistry, Division of Oral Infection and
Disease Control, Osaka University Graduate School of Dentistry, Suita, Osaka, Japan
1

Mineralized Tissue061: Trehalose, a natural sweetening compound, suppresses osteoclast differentiation.
S. NEGISHI, K. YOSHIMURA, R. KAMIJO
Department of Biochemistry, Showa University School of Dentistry062: Computational chemistry of phospholipid mineralization

E. S. HARA1, N. KUNIOSHI2, M. OKADA1, T. MATSUMOTO1
1
Department of Biomaterials, Okayama University Graduate School of Medicine, Dentistry andPharmaceutical Sciences, 2Department of Materials Science, Graduate School of Fundamental Scienceand Engineering, Waseda University, Tokyo, Japan

063: Histological study of dentin bridge formed beneath MTA after pulpotomies in rat
molarsA. TANAKA, T. TANASE, K. KOJIMA, H. HOMMA, A. SAKURAI, S. SHINTANI
Department of Pediatric Dentistry, Tokyo Dental College, Tokyo, Japan

Implantology Research064: The effect of micro-sized titanium on osteoblast differentiation

N. OMORI, H. NAKATA, S. KURODA
Department of Oral Implantology and Regenerative Dental Medicine, Division of Oral Health
Sciences, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University

Dental Materials 5: Biocompatibility, Bioengineering and Biologic Effects of Materials
065: Comparison in physical properties of synthetic carbonate apatite and allogeneic bone
graft substitute
N. KIMURA, S. KATO, E. ARIMA, N. KITAMURA, K. YAMANAKA, F. FUSEJIMAGC Corporation, Tokyo, Japan

066: Novel bio-active adhesive monomer CMET stimulates human dental pulp stem cells
differentiation toward odontoblast phenotype: a comparative study
Y.J. QIU, T. SAITO

─ 20 ─

Division of Clinical Cariology and Endodontology, Department of Oral Rehabilitation, Health
Sciences University of Hokkaido, Hokkaido, Japan

067: Hydrogel-based biomechanical environment for understanding Meckel's cartilage
fate
M. FARAHAT1, G. A. S. KAZI2, E.S. HARA1, T. MATSUMOTO1
1
Department of Biomaterials, Okayama University, Okayama, Japan, 2Department of Applied Life
Systems Engineering, Graduate School of Science and Engineering, Yamagata University

Diagnostic Sciences
068: Evaluation of Interleukin – 8 In Human Dental Pulp

S. TALWAR1, R.R. NAWAL1, A. KAUSHIK1, R. KONER2
1
CONSERVATIVE DENTISTRY AND ENDODONTICS, MAULANA AZAD INSTITUTE OFDENTAL SCIENCES, New Delhi, DELHI, INDIA, 2BIOCHEMISTRY, MAULANA AZADMEDICAL COLLEGE, NEW DELHI, DELHI, INDIA

Pulp Biology & Regeneration Research069: Interaction analysis of protein S100A7 in dental pulp tissue

M. WATANABE, M. OKAMOTO, H. HAILING, S. MATSUMOTO, K. MORIYAMA, Y.
TAKAHASHI, M. HAYASHI
dentistry, Osaka University, Suita, Japan

070: Lyve-1+ Pulpal Macrophages: M2-polarization and Response to Cavity Preparation

K. THOAI, K. TAZAWA, K. NARA, M. FUJII, K. HASHIMOTO, S. NODA, N. KAWASHIMA, T.
OKIJI
Department of Pulp Biology and Endodontics, Tokyo Medical and Dental University, Tokyo, Japan

071: DNA methylation of GJA1, BMP2 and BMP4 in a human cementoblast cell line
induced by lipopolysaccharide.

T. MURAMATSU1, F. KOBAYASHI2, O. UEHARA3, C. ITO4, M. FURUSAWA2, Y. ABIKO5
1
Department of Operative Dentistry, Cariology and Pulp Biology, Tokyo Dental College, Tokyo,
Japan, 2Department of Endodontics, Tokyo Dental College, Tokyo, Japan, 3Department of Oral Growthand Development, Health Sciences University of Hokkaido, Tobetsu, Japan., 4Oral Health Science
Center, Tokyo Dental College, Tokyo, Japan., 5Department of Human Biology and Pathophysiology,
School of Dentistry, Health Sciences University of Hokkaido, Tobetsu, Japan.

072: Effects of Non-thermal atmospheric pressure plasma on human deciduous dental
pulp fibroblast-like cells

M. OKUNO1, K. HARADA2, S. AOKI1, S. KAWAI2, K. ARITA2
Department of Pediatric Dentistry, Graduate School of Dentistry, Osaka Dental University, Osaka,
Japan, 2Department of Pediatric Dentistry, School of Dentistry, Osaka Dental University, Osaka, Japan1

Dental Materials 5: Biocompatibility, Bioengineering and Biologic Effects of Materials
073: Effect of Lithium Carbonate on the Healing of Apical Periodontitis

T. KAGIOKA, S. ITOH, H. NARUSE, Y. ITO, M. HAYASHI
Department of Restorative Dentistry and Endodontology, Osaka University Graduate School of
Dentistry, Suita, Japan─ 21 ─

Pulp Biology & Regeneration Research
074: Large-conductance Ca2+-activated K+ Channels in Human Cementoblasts
S. KAMATA, M. KIMURA, Y. SHIBUKAWA, S. YAMASHITATokyo Dental College

075: Activation of CGRP receptors increased intracellular cAMP level in odontoblasts

N. SAITO, M. KIMURA, H. MOCHIZUKI, K. KOUNO, M. ANDO, S. OHYAMA, T. ICHINOHE, Y.
SHIBUKAWA
Tokyo Dental College, Tokyo, Japan

076: Plasma membrane Ca2+-ATPase regulates dentin formation and mineralization.
H. MOCHIZUKI, M. KIMURA, S. OHYAMA, K. KOUNO, M. ANDO, Y. SHIBUKAWA
Tokyo Dental College

Microbiology/Immunology
077: Functional expression of mechanosensitive ion channel in mouse osteoblasts

S. NAGAI1, K. KITAMURA3, M. KIMURA2, Y. SHIBUKAWA2, H. YAMAMOTO3, A.
KATAKURA1
1
Department of Oral Pathobiological Science and surgery, Tokyo Dental College, Tokyo, Japan,
2
Department of Physiology, Tokyo Dental College, Tokyo, Japan, 3Department of Histology andDevelopmental Biology, Tokyo Dental College, Tokyo, Japan

Pharmacology/Therapeutics/Toxicology
078: Activation of mechano-sensitive ion channels in cancer cells establishes paracrine
network via endothelin signaling

M. ISHIZAKI1, M. MATSUNAGA1, T. YAZAKI1, N. SAITOH1, S. OHYAMA2, M. KIMURA2, Y.
SHIBUKAWA2, T. ICHINOHE1
1
Department of Dental Anesthesiology, Tokyo Dental College, Tokyo, Japan, 2Department of
Physiology, Tokyo Dental College, Tokyo, Japan

Neuroscience
079: Mechanical stimulation-induced intercellular communication in trigeminal ganglion
neurons
T. YAZAKI1, M. ISHIZAKI1, M. MATSUNAGA1, S. OHYAMA2, H. KURODA3, M. KIMURA2, Y.
SHIBUKAWA2, T. ICHINOHE1,2
1
Department of Dental anesthesiology, Tokyo Dental Colledge, Tokyo, Japan, 2Department of
Physiology, Tokyo Dental Colledge, Tokyo Japan, 3Graduate School of Dentistly Department of
Critical Care Medicine and Dentistly, Kanagawa Dental University, Kanagawa Japan

080: Piezo1 channel activation evokes mechanosensitive Ca2+ signaling in humanodontoblast
M. MATSUNAGA1, M. KIMURA2, M. ISHIZAKI1,2, T. YAZAKI1,2, S. OHYAMA2, Y.
SHIBUKAWA2, T. ICHINOHE1
1
Dental Anesthesia, Tokyo Dental College, 2Physiology, Tokyo Dental College

─ 22 ─

Oral & Maxillofacial Surgery Research
081: Effects of preemptive analgesia with intravenous acetaminophen on postoperat ive
pain relief in patients undergoing third molar surgery: a prospective, single-blind,randomized controlled trial
K. KANO1,2, K. KAWAMURA3, T. MIYAKE3
1
Graduate School of Dentistry, Osaka Dental University, Osaka, Japan, 2Department of Dentistry
and Oral Surgery, Uji Takeda Hospital, Kyoto, Japan, 3Department of Preventive and Community
Dentistry, Osaka Dental University, Osaka, Japan

Diagnostic Sciences
082: Diagnostic and Prognostic Applications of Artificial Intelligence-based Radiology in
Head and Neck Region
M. Poorsattar1, A. Poursattar Bejehmir2
1
Private section, San Antonio, Texas, UNITED STATES, 2Private Section, Toronto, Ontario,
CANADAe-Oral Health Network
083: Revolutionalized Concept of Digitalizing Dental Treatment Contents using Machine
Learning

S. OKA1, K. NOZAKI2, M. HAYASHI1
1
Department of Restorative Dentistry and Endodontology, Osaka University Graduate School of
Dentistry, Osaka, Japan, 2Division for Medical Information, Osaka University Dental Hospital, Osaka,
Japan

Education Research
084: Evaluation of simulation training courses on basic clinical skills for geriatricdentistry for trainee dentists

H. TAKETA1, T. YOSHIDA2, A. YABE1, N. SHIOTSU1, T. KONO1, H. SHIRAI1, Y. TORII1
1
Comprehensive Dental Clinic, Okayama University Hospital, Okayama, Japan., 2Center for
Education in Medicine and Health Sciences (Dental Education), Okayama University, Okayama,
Japan.

Behavioral, Epidemiologic and Health Services Research
085: Needs Of Dentists During The Covid-19 Pandemic In Nepal

Y. HARADA1, D. PRAJAPATI2, H. IWASHITA1, T. SUGISHITA1
1
International Affairs and Tropical Medicine, Tokyo Women's Medical University, 2Community andPublic Health Dentistry, Dhulikhel Hospital, Kathmandu University School of Medical Science

086: Oral conditions matter for general health of community-dwelling elderly population
Y. NAKAI1, Y. NAGATANI1, M. OZAKI2, K. OHUCHI2, H. KINOSHITA2, A. HIRANO2, T.
YANAGAWA2
1
Department of Dental Hygiene, University of Shizuoka Junior College, Shizuoka, Japan, 2Shizuoka
Dental Association, Shizuoka, Japan─ 23 ─

Oral Health Research
087: Comparative study of plaque removal effect on Japanese commercial toothbrushes.
C. HSU, K. SHINADA
Department of Preventive Oral Health Care Sciences, Tokyo Medical and Dental University, Tokyo,
Japan

088: Comparing the oral health-related quality of life of people with diabetes and people
without diabetes at a Tertiary Hospital in Nigeria
N. A. Ilochonwu
Preventive Dentistry, University of Port Harcourt, Choba, Port Harcourt, Rivers State, NIGERIA

Prosthodontics Research089: Survey Of Smile Satisfaction And Desired Treatments Among Medical And Dental
Students.

T. Khatri1, S. Butt2, A. Tufail1, R. Fatima1, Z. Irfan1
1
University of Health Sciences, Karachi, Sindh, PAKISTAN, 2University, Karachi, Sindh, PAKISTAN─ 24 ─