Main Program(On Site & Live Streaming Program)
December 15 (Tuesday)
7:00 - 7:25

Keynote 6 ETMR and other Embryonal Tumors
Understanding the clinical and biological landscape of ETMRs
Annie Huang (Canada)

7:25 - 7:50

Keynote 7 Craniopharyngioma
Treatment Challenges of Adamantinomatous Craniopharyngioma
Ute Bartels (Canada)

7:50 - 8:15

Special Lecture 5
Replication repair deﬁciency and hypermutation in childhood brain tumors:
Insights on germline and somatic mutagenesis
Uri Tabori (Canada)

8:15 - 8:40

Keynote 8 Low Grade Glioma (clinical)

Paediatric Low Grade Gliomas: clinical management
Eric Bouﬀet (Canada)
8:40 - 9:05

Keynote 9 DIPG
Molecular pathways and therapeutic opportunities in DIPG
Nada Jabado (Canada)

9:05 - 9:30

Keynote 10 HGG (clinical)

Translating the advancing biology of CNS high-grade gliomas into actual
patient beneﬁt
Mark Kieran (USA)9:30 - 9:55

Late-breaking Lecture Ependymoma ACNS0831 Clinical Trial

ACNS0831, Phase III Randomized Trial of Post-Radiation Chemotherapy inPatients with Newly Diagnosed Ependymoma Ages 1 to 21 years
Amy Smith (USA)20

Main Program(On Site & Live Streaming Program)
9:55 - 10:20

Keynote 11 Ependymoma (clinical)

Posterior Fossa Ependymoma (PF EPN): Reaching for Eﬀective Therapy
while exploring new Biology
Nicholas Foreman (USA)
10:20 - 10:45

Keynote 12
Pathology and Molecular Classiﬁcation (WHO Classiﬁcation and cIMPACT-NOW)

Histopathology and molecular pathology in the diagnosis of pediatric CNStumors - WHO Classiﬁcation, Edition 5
David Ellison (USA)10:45 - 11:10

Keynote 13 Epidemiology
Know the facts! An update on causes and risk factors for childhood brain tumors
Jill Barnholtz-Sloan (USA)11:10 - 11:50

Special Lecture 6

Neuroﬁbromatosis type 1
Murali Chintagumpala (USA)11:50 - 12:00

Break

12:00 - 13:00

Luncheon Seminar 2

Molecular pathogenesis and treatment of primary central nervous system lymphoma:
Evidence and perspectives(No On-Demand Program)

Motoo Nagane (Japan)

21

Main Program(On Site & Live Streaming Program)
13:00 - 14:20

13:00 - 13:30

CNS Germ Cell Tumors Session

Special Lecture 7(basic) Mechanism and In Vitro Reconstitution of Mammalian Germ-Cell Development
Mitinori Saitou (Japan)

13:30 - 13:55

Keynote 14(clinical) Treatment of CNS germ cell tumors, from the past to the future
Masao Matsutani (Japan)

13:55 - 14:20

Keynote 15(clinical) Korean studies in intracranial germ cell tumors
Chang-Ok Suh (Korea)

14:20 - 14:50

Special Lecture 8
Deciphering the origin of somatic mutations in brain tumors
Jeong Ho Lee (Korea)

14:50 - 15:20

Special Lecture 9
Japanese platform for cancer genomic medicine; a new hope for children
Hiroyuki Mano (Japan)

15:20 - 15:50

Afternoon Seminar 2 Nanopore Sequencing
Characterization of complicated structural variants with local copy-number changes incancer genomes using PromethION
Yutaka Suzuki (Japan)

15:50 - 16:20

Meet-the-Experts

Endoscopic endonasal resection of sellar and parasellar lesions for pediatric andadolescent patients
Yudo Ishii (Japan)

22

Main Program(On Site & Live Streaming Program)
16:20 - 17:10
16:20 - 16:45

Neurosurgery Session
Keynote 16
Overcoming the limitation of current treatment for malignant pediatric brain tumors:
updating neurosurgical points of views
Chae-Yong Kim (Korea)

16:45 - 17:10

Keynote 17
Surgical challenges and solutions for improving surgical outcome in Ependymoma
Surgery
Conor Mallucci (UK)

17:10 - 17:40

Special Lecture 10

Hereditary predisposition to childhood cancer
Stefan Pﬁster (Germany)
17:40 - 19:20
17:40 - 18:00

Forum 3 Posterior Fossa Syndrome
Symposium on cerebellar mutism syndrome
Barry Pizer (UK)18:00 - 18:20

Radiology of Cerebellar Mutism Syndrome
Shivaram Avula (UK)

18:20 - 18:40

Surgical aspects to minimise cerebellar mutism syndrome- have we made any progress?
Conor Mallucci (UK)

18:40 - 18:50“The Nordic-European study of the cerebellar mutism syndrome”‒ Establishing the Study
Astrid Sehested (Denmark)18:50 - 19:00

Cerebellar Mutism Syndrome and the surgical risk factors: a prospective multicentre
study of 500 patients undergoing tumour surgery in the posterior fossa
Jonathan Kjær Grønbæk (Denmark)19:00 - 19:10

Future Directions for Research in Cerebellar Mutism Syndrome
Astrid Sehested (Denmark)19:10 - 19:20

19:30 - 21:30

Panel discussion/Q&A

Evening Seminar23