Luncheon Seminar (excerpt) of JAAM46
Participants of all luncheon seminars will be required to show their Tickets for Luncheon Seminar, until
seminar beginning time. Tickets for Luncheon Seminar are provided PACIFICO YOKOHAMA Conference
center 1st fl. "Foyer". (see p.3)

19. November (Day 1)
12:00 - 13:00

Site 2 : Room 503 (5th fl.)Luncheon Seminar 2
Chairperson: Tokyo Metropolitan Children's Medical Center (Japan)

LS2

Naoki Shimizu

Improving the Certainty and Probability of Successful Resuscitation
for Children…Past, Present and Future

Endowed Chair, Professor, Department of Anesthesiology and Critical Care Medicine Medical Director,
CHOP Center for Simulation, Advanced Education, and Innovation Associate Director, University of Pennsylvania Center for Resuscitation Science (USA)Vinay Nadkarni
40 million children are at risk for respiratory failure and shock evolving to cardiac arrest each in the USA
alone. Of these, >10,000/year suffer cardiac arrest, with favorable outcomes in 5-40%. Clinical deterioration
events requiring emergency response for respiratory failure and shock are 30 times more common thancardiac arrest ( ～ 300,000/year), and are a major source of preventable harm. All systems of care thatprovide care for children require pediatric-specific medical devices, training, detection and response systems
to enhance safe and accountable care. We will review the pioneering breakthroughs and innovative strategies
to prevent, prepare for, and optimize resuscitation with a focus on long-term quality of life. Insights gained
from examples of extraordinary care, pioneering translational research, and exceptional global
implementation, training and support will launch meaningful discussions of how the past and present“learning laboratories" will lead to breakthroughs that will revolutionize the future approach to resuscitation.
(Sponsored: Asahi Kasei ZOLL Medical Corporation)

19. November (Day 1)
12:00 - 13:00

Site 3 : Room 501 (5th fl.)Luncheon Seminar 3
Chairperson: Kagawa University (Japan)

Yasuhiro Kuroda

LS3-1 （in Japanese）地域全体で取り組む重症心不全・CPA 患者の治療―
新しいドクターカーシステム構築から植え込み型 VAD ハブ施設設立まで
横浜市立大学大学院

竹内医学研究科

救急医学教室一郎

LS3-2 Global trends on ECPR: Let's join a global resuscitation network
Chairman, Emergency Medicine, Donald and Barbara Zucker School of Medicine at Hofstra(USA)

Lance B. Becker
As ECPB is performed in more a more sites, a global resuscitation network would advance this life saving
science at a far more rapid pace than our current trajectory. Consider that a typical single center ofresuscitation excellence doing ECPB may only attempt ECPB on a handful of patients each year – but bycomparison a global network could attempt resuscitation on hundreds of patients. This would be sufficient toconduct ongoing randomized controlled adaptive trials that would answer many questions about the optimal
conditions for ECPR. Without such a network it is unlikely that we will rapidly progress to gain theseanswers. It is time for the resuscitation community to join together globally, to share data, to work together
to design controlled studies, and to further the science of ECPR plus adjuvant therapies.
(Sponsored: Terumo Corporation)

20. November (Day 2)
12:20 - 13:20

Site 3 : Room 501 (5th fl.)Luncheon Seminar 14
Chairperson: Nippon Medical School (Japan)

LS14

Hiroyuki Yokota

Multimodal Neuromonitoring in Neurocritical Care

Anesthesiology and Intensive Care Medicine Center for Cardiac Arrest at Lund University (Sweden)Hans Friberg
Introduction: The pathophysiology of brain injury in critically ill patients is complex and involves several
detrimental pathways as well as pathways important for repair and recovery. While brain injury often is a
result of a primary condition such as stroke or trauma, it is commonly aggravated by secondary insults. A
clinical neurological examination is the single most important component of neuromonitoring but is often notenough, especially in the more severely injured patients in whom sedation is mandated. In this review, wewill

discusssomeclinicallyavailable

neuromonitoring

techniques

includingneurophysiology(EEG/cEEG/SSEP), brain tissue oxygen monitoring, automated quantitative pupillometry and biomarkers ofbrain damage in biological tissues. How these techniques can be integrated in multimodal algorithms toimprove diagnostic procedures, individualize therapy and assist in prognostication will be addressed.
Aims: The overall aims of neuromonitoring in the ICU:
- to improve the understanding of cerebral disease in the critically ill- to identify worsening neurological conditions and secondary brain insults- to collect and combine substrate for guidance and individualization of therapy- to assist in prognostication
Preliminary data: Data from a prospective observational sub-study (N=134) of the Target TemperatureManagement Trial (TTM-trial) investigating the temporal development of epileptiform activity and EEG
background and the association to outcome will be presented. Data from a prospective European multicentre
study (N=456) examining the accuracy of automated quantitative pupillometry will be presented. Establishedas well as novel biomarkers for brain damage in biological tissues will be presented and discussed.
Conclusion: A careful clinical neurological examination is a fundamental part of neuromonitoring. In order
to individualize care and optimize therapy for the critically ill patient in Neurocritical Care, relevant
neuromonitoring techniques should be added and integrated in multimodal algorithms.
(Sponsored: IMI Co., Ltd.)