No. DEFC0512

DEHYDRATED SOLVENT K

Date of issue : 3 Jun. 2020
Date of revision : 1 Jan. 2021
Safety Data Sheet

1.

Product and company identification
Product name

: DEHYDRATED SOLVENT K

Part No.

: D312135-1

Name of manufacturer

2.

: HIRANUMA Co., Ltd.

Address: 1739 Motoyoshida, Mito, Ibaraki, 310-0836, JAPANName of section: Quality assurance department

Telephone number: +81-29-247-7343

Facsimile number: +81-29-240-0381

Mail address: info-f@hiranuma.com

Summary of danger and Hazard
GHS classification
Physical and chemical hazard
Flammable liquids ：Out of category
Pyrophoric liquids ：Out of category
Human health hazard
Acute toxicity (oral)：Category 3
Acute toxicity (dermal)：Category 2
Acute toxicity (inhalation: vapors)：Category 2
Skin corrosion/Irritation：Category 2
Serious eye damage/eye irritation：Category 1
Germ cell mutagenicity：Category 2
Carcinogenicity：Category 1A

Reproductive toxicity：Category 2
Specific target organ systemic toxicity (single exposure)：Category 1, Category 3 （anesthetic action）
Specific target organ systemic toxicity (repeated exposure)－ 1/10 －No. DEFC0512

DEHYDRATED SOLVENT K：Category 1
Environmental hazard
Hazardous to the aquatic environment-acute hazard：Category 3
Hazardous to the aquatic environment-chronic hazard：Category 1
Pictogram or symbol

Signal word

：Danger

Hazard statement：Toxic if swallowed
Fatal in contact with skin
Fatal if inhaled
Causes skin irritation
Causes serious eye damage
Suspected of causing genetic defects
May cause cancer
Suspected of damaging fertility or the unborn childCauses damage to organs (central nervous system, blood,
respiratory organs, liver, kidney)
May cause drowsiness and dizziness
Causes damage to organs (central nervous system, blood,
kidney, liver, respiratory organs) through prolonged or repeatedexposureHarmful to aquatic life
Very toxic to aquatic life with long lasting effects

Cautions
Safety measurements：Do not handle until all safety precautions have been read andunderstood.
Do not breathe dust, mist, and vapor.
Do not get in eyes, on skin, or on clothing.
Use only in a well-ventilated area.
Avoid release to the environment.
Do not eat, drink or smoke when using this product.
Wear appropriate protective gloves, glasses, clothing, faceshield, or mask.
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DEHYDRATED SOLVENT K

Wash protective equipment thoroughly after use.
Wash hands thoroughly after handling.
First-aid measures ：If inhaled : Remove victim to fresh air and keep at rest in aposition comfortable for breathing. Immediately get medical
treatment.
If swallowed: Induce vomiting, if possible, and rinse mouth.
Immediately get medical treatment.
If in eyes : Rinse cautiously with water for several minutes.
Get medical treatment.
If on skin : Remove contaminated clothing and the substance.
Immediately get medical treatment.
If exposed, get medical treatment.
Get medical treatment, if you feel unwell.
Collect leakage
Storage：Tightly container closed and store in a well-ventilated area.
Store locked up.

Disposal：Dispose of contents and containers appropriately in accordancewith related regulations.

3.

Composition/Information on ingredients
Substance/Mixture：Mixture
Chemical name or commercial name
：Chloroform, 2-Chloroethanol
Synonyms：2-Chloroethanol:ethylenechlorohydrin

Ingredients and composition：Chloroform 55%, 2-Chloroethanol 45%
Chemical formula：Chloroform CHCl3
2-Chloroethanol ClCH 2CH2OH

CAS No.

：Chloroform 67-66-3
2-Chloroethanol 107-07-3

TSCA Inventory：Chloroform Registered
2-Chloroethanol Registered

EINECS No.

：Chloroform 2006638
2-Chloroethanol 2034597

4.

First aid measures
Inhalation：Remove the victim to fresh air, and make him blow his noseand gargle.
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DEHYDRATED SOLVENT K

Skin contact：Wash the affected areas under running water.

Eye contact：Wash the affected areas under running water for at least 15
minutes. Get medical treatment.

Ingestion：The chemical is volatile. Do not induce vomiting because it
increases the risk of aspiration into the lungs. Get medical
attention immediately. If necessary, rinse mouth with water.

Anticipated acute and delayed symptoms：Inhalation may causes cough, dizziness, lethargy, sensory
paralysis, headache, nausea, vomiting, unconsciousness these
symptoms may be late to develop. these symptoms may belate to develop.
Protection for first aid person：Rescuers should wear proper protective equipment like rubber
gloves, goggles.

5.

Fire fighting measures
Extinguishing media：Dry chemical powder, carbon dioxide, dry sand, foam

Prohibited extinguishing media：Water spray
Danger and hazards under fire
：Thermal decomposition emits harmful chlorine, hydrogen chloride,
phosgene gas.
Particular fire fighting：Move containers from fire area if it can be done without risk,
if not possible, apply water from a safe distance to cool andprotect surrounding area.
Fight fire from windward.
Dry chemical powder, carbon dioxide or dry sand should be
used for small fires. Foam extinguisher is effective for a large
scale fire.
Protection for firefighters：Firefighters should wear protective equipment.

6.

Accidental release measures
Cautions for personnel：Wear proper equipment and avoid contact with skin andinhalation of vapor. Conduct operations from upwind andevacuate people downwind. Remove all sources of ignition.
Keep away personnel except for authorized ones from spillage－ 4/10 －No. DEFC0512

DEHYDRATED SOLVENT K

area by stretching ropes.
Cautions for environment：Attention should be given to avoid damage to the environment
by flowing of spillage to rivers.
Removal measure：Absorb spill with inert material (e.g., diatomaceous earth, sand)and flush spillage area with copious amounts of water.

7.

Cautions of handling and storage
Handling
Engineering measures：Wear proper protective equipment to avoid contact with skin or
inhalation of vapor.
Cautions for safety handling：Use with an enclosed system or a local exhaust ventilation. Use
in well-ventilated areas.
Storage
Adequate storage condition：Store in a dark, cool place and tightly closed.
Safety adequate container materials：Glass, fluorine resin
Do not use vinyl chloride resin, polyethylene, synthetic rubber
etc.

8.

Exposure control/Personal protection
Engineering measures：Use with an enclosed system or a local exhaust ventilation.
Control parameters
ACGIH(2015)：10ppm(as chloroform)(TLV-TWA)
1ppm(upper limit)(as 2-chloroethanol)(TLV-STEL)

Protective equipment
Respiration protective equipment：If necessary, wear chemical cartridge respirator with an organic
vapor cartage
Hands protective equipment：Impervious protective gloves
Eyes protective equipment：Safety goggles
Skin and body protective equipment：Protective clothing, protective boots－ 5/10 －No. DEFC0512

9.

DEHYDRATED SOLVENT K

Physical and chemical properties
Appearance：Liquid

Color：Colorless - pale yellow

Odor：Sweet acrid odor

Odor threshold：30ppm(as chloroform)

Boiling point：61.15 C(as chloroform)

Melting point：-63.55 C(as chloroform)

Flash point：Noncombustible

Vapor pressure：212hPa (20 C)(as chloroform)

Vapor density：3.6

Density：1.34g/cm3 (20 C)

Solubility
Solubility in solvents：Water ; Soluble
Organic solvents; Readily soluble in ethanol, diethyl ether.
log Pow：1.97 (as chloroform)

10. Stability and reactivity
Stability：Decomposes by light or heat and emits harmful phosgene.

Reactivity：If contacted with strong alkaline solution, may cause explode.

Incompatible conditions：Light, heat
Incompatible materials ：Oxidizing substances
Hazardous decomposition products：Carbon monoxide, Chlorine, Hydrogen chloride, Phosgene

11. Toxicological information
Acute toxicity：Toxic if swallowed(category 3)
Fatal in case of contact with skin(category 2)
Fatal if inhaled(vapor)(category 2)
Inhalation (dust, mist) : Not possible to classify because of
insufficient data.
(as Chloroform)
rat oral LD50=440mg/kg
rabbit skin LDLo>3980mg/kg
rat inhalation LC50=9636ppm/4H(vapor)(as 2-Chloroethanol)－ 6/10 －No. DEFC0512

DEHYDRATED SOLVENT K

rat oral LD50=71mg/kg
rabbit skin LD50=67mg/kg
mouse inhalation LC50=0.3mg/L(vapor)
Skin corrosion/irritation：Causes skin irritation(category 2)
Based on the description of the result of the skin irritation
test using rabbits that chloroform causes slight congestion in
the skin, moderate skin necrosis and incrustation, theclassification is set into category 1A.
Serious eye damage/eye irritation：Causes serious eye damage(category 1)
Based on thedescription of the result of eyes irritation test
using rabbits that chloroform causes severe eye irritation, withmydriasis and keratitis. Translucent zones in the cornea wereobserved in four animals and a purulent hemorrhagic discharge
was also reported (number of rabbits unknown). it wasclassified into category 1.
Respiratory sensitization or Skin sensitization：Respiratory sensitization : Not possible to classify because of
insufficient data.
Skin sensitization : Not possible to classify because of
insufficient data.
Mutagenicity：Suspected of causing genetic defects(category 2)
Based on positive data of chloroform on somatic cellmutagenicity tests in vivo (micronucleus and chromosome
aberration tests), and 2-chloroethanol has positive result fromin vivo chromosome aberration tests in rat bone-marrow(inhalation). the classification is set to category 2.

Carcinogenic effects ：May cause cancer(category 1A)
Since there is the proof about 2-chloroethanol that it iscarcinogenic to humans in epidemiological data, it is set tocategory 1A.
Effects on the reproductive system：Suspected of damaging fertility or the unborn child(category 2)
Based on the evidence about chloroform of a decline infertility, a decrease in crown-rump length, delayed calcificationof the skull and lumbar ribs, an increase in cleft palate,malformation of the interperietal bone, increased incidence of－ 7/10 －No. DEFC0512

DEHYDRATED SOLVENT K

anuary, brachyury and anal atresia within a litter, subcutaneousedema and increased rates of absorbed embryos at dosing
levels toxic to parent animals in mouse three-generation tests
and rat and mouse teratogenicity tests.
Specific target organ systemic toxicity single exposure：Cause damage to organs (central nervous system, blood,cardiovascular, respiratory organs, liver, kidneys)(category 1)
May cause drowsiness and dizziness(category 3)
Based on the human evidence of chloroform including necrosisof hepatic cells, liver damage, jaundice, hypertrophy of the liver,kidney damage, stertorous respiration, cyanosis and excessive
sweating and the evidence from animal studies including
centrilobular fatty infiltration and necrosis of the liver,piloerection, sedation, musclar relaxation, ataxia, debility, partiallywatery eyes and necrosis of proximal convoluted tubules.
The effects of 2-chloroethanol on the central nervous system,
cardiovascular system, renal, lung, and liver are observed. And
there is the description that the substance irritates the airway
seriously. Moreover the anesthetic by inhalation is indicated.
Specific target organ systemic toxicity repeated exposure：Cause damage to organs (central nervous system, blood,
kidneys, liver, respiratory organs) through prolonged or repeatedexposure(category 1)
Based on the human evidence of chloroform including fatigue,thirst, gastrointestinal pain, frequent and painful urination,difficulty in concentration, depression, irritability, jaundice caused
by liver damage after exposure to chloroform.
The effects of 2-chlororethanol on blood, kidney, liver wereobserved.
Aspiration hazard：Not possible to classify because of insufficient data.

12. Ecological information
Ecotoxicity
Fish toxicity：Harmful to aquatic life(category 3)
Very toxic to aquatic life with long lasting effects(category 1)(as Chloroform)
Chlamydomonas EC50=13.3mg/L/72H
Fish(rainbow trout) NOEC=0.059mg/L/72H

Persistence and degradability－ 8/10 －No. DEFC0512

DEHYDRATED SOLVENT K：Chloroform has no biodegradability.
0% by BOD
Bioaccumulative potential：Chloroform is considered low or non bioaccumulativity or
residualibity in fish or shells.
Concentration Carp 1.4-4.7 fold(1mg/L)
Carp 4.1-13 fold(0.1mg/L)
Mobility in soil

：Chloroform may transfer to the atmosphere, the aquatic
environment, and soil environment based on its physicochemical
properties.

13. Disposal consideration
Residual disposal：Mix the material with combustible solvent and burn in a chemical
incinerator equipped with an afterburner and scrubber as
possible as high temperature. Or else consult approved disposal
companies.

<Note>：Alkaline solution should be used for cleaning liquid of thescrubber. The incinerator should be suitable for burning organic
halogen compounds.

Containers：In case of disposal of empty bottles, dispose bottles after
removing the content thoroughly.

14. Transport information
UN class：Class 6.1(Toxic substances) P. G. Ⅰ

UN number：2810

Marine regulation information
UN No.

：2810

Proper shipping name：TOXIC LIQUID, ORGANIC, N.O.S.
Class

：6.1

Sub risk：-

Packing group：Ⅰ

Marine pollutant：Not applicable

Aviation regulation information
UN No.

：2810

Proper shipping name
：Toxic liquid, organic, n.o.s.
Class

：6.1

Sub risk：－ 9/10 －No. DEFC0512

DEHYDRATED SOLVENT K

Packing group：Ⅰ

15. Regulatory information
Ensure this material in compliance with federal requirements
and ensure conformity to local regulations.

16. Other information
References
1) Company data on file (SDS provided by manufacturer)2) NITE: National Institute of Technology and Evaluation＊The information contained herein is based on several references and the present state of ourknowledge. However the SDS does not always cover all information about the product, handle theproduct carefully. The information is intended to ordinary usage, in case of particular handlings,
conduct appropriate safety measurements. The information herein is only provision of information,and it does not represent a guarantee the properties of the product. The Safety Data Sheet(SDS) is
prepared based on JIS Z7253, and it has the same required elements on the Material Safety Data
Sheet(MSDS) which is prepared based on JIS Z7250:2010.

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