The 15th SymposiumofJapanese Society of Computational Statistics
ProgramSimultaneously held withInternational Conference on New Trends in Computational Statistics
with Biomedical Applications (ICNCB)

August 31 (Friday) – September 1 (Saturday), 2001
Osaka University Convention Center
OSAKA, JAPANThe 15th Symposium of JSCS
(Japanese Society of Computational Statistics)
ProgramSorry, all the sessions are held in Japanese.

August 30 (Thursday)
13:15 – 14:15 ICNCB Key-note Lecture 1
Chair: Hiroyuki Uesaka (Eli Lilly Japan K. K.)•Sandra Close Kirkwood (Eli Lilly and Company, USA)The role of statistics in pharmacogenomics

14:15 – 15:15 ICNCB Key-note Lecture 2
Chair: Yutaka Tanaka (Okayama University)•Wing Kam Fung (University of Hong Kong)
The role of statistics in pharmacogenomics

18:00 –Welcome Reception
at Restaurant Rosen (in Osaka University Suita Campus)

August 31 (Friday) A.M.
9:50 – 10:00

Opening Address
Shingo Shirahata (Chair of the 15th Symopsium of JSCS, Osaka University)

10:00 – 11:00

Session 1
Chair: Yoshiro Yamamoto (Tama University)•Hiroyuki Matsuura (National Graduate Institute for Policy Studies), Masahiro Nakano (Universityof Occupational and Environmental Health) and Iwao Fujimasa (National Graduate Institute for
Policy Studies)
Quantum sociodynamics based on modern physics (path integral method)•Tuneshi Obata (Oita University)
Analysis of ranked voting data by using data envelopment analysis•

Hirohisa Hirai, Wataru Sakamoto and Shingo Shirahata (Osaka University)
Cost estimation using nonparametric regression analysis

11:00 – 11:30

Coffee Break

11:30 – 12:30

Software Demonstration
Chair: Tsunehiro Fujisaki (Kagoshima National College of Technology)•Tsukasa Tazawa and MunehisaMizuno (Mathematical System Inc.)S-PLUS Version 6, and its Java new technology•

Hiroshi Chiba (The Numerical Algorithm Group Japan K. K.)
NAG statistical analysis add-ins for Excel Professional Edition•

Masahiro Hirao (SAS Institute Japan Ltd.)
Introduction on extended functions of SAS System Version 8e and new products•

Kyoko Takenaka and Akio Noda (SAS Institute Japan Ltd.)The Introduction of JMP4•

Satoshi Senda (Sumisho Computer Systems Corp.)
Missing data analysis software "Solas"

12:30 – 14:00 Lunch

August 31 (Friday) P.M.
14:00 – 15:00 Session 2
Chair: Koji Kurihara (Okayama University)•Taichi Inaba (Kobe University)
Interval estimation of the difference of two ratios•

Akihiko Matsuo (Kansai University)
On the performance of unconditional test using modified two dimensional statistic•

Daiki Asano and Yoshiharu Sato (Hokkaido University)
Additive fuzzy clustering model using normed similarity function

15:00 – 15:40 Coffee Break
15:40 – 17:10 Special Session
Use of Foreign Data in Drug Development: How to Use E5 Guideline and the Related Issues
Organizers: Tohru Uwoi (Yamanouchi Pharmaceutical Co., Ltd.) andToshimitsu Hamasaki (Pfizer Pharmaceuticals Inc.)•Toshimitsu Hamasaki* and Tatsuya Isomura (Pfizer Pharmaceuticals Co., Ltd.)
Issues in use of foreign data in drug development•

Kazuhiko Kuribayashi* and Hiroyuki Uesaka (Eli Lilly Japan K.K.)
How to characterize ethnic similarity/difference in pharmacokinetics•

Masako Nishikawa* (Aventis Pharma Ltd.) and Masahiro Takeuchi (Kitasato University)
On predictability of drugs' profiles from existing foreign clinical data

18:30 –ICNCB Banquet
at Crystal Hall in Senri Hankyu Hotel (Toyonaka, Osaka)
Pick-up buses will drive from Osaka University to Senri Hankyu Hotel.

September 1 (Saturday) A.M.
9:30 – 11:00

Session 3
Chair: Hiroyuki Uesaka (Eli Lilly Japan K. K.)•Yoshihiro Yamanishi and Yutaka Tanaka (Okayama University)
Penalized canonical discriminant analysis for functional data•

Masaki Fujisawa (Grelan Pharmaceutical Co., Ltd.), Wataru Sakamoto and Masashi Goto (OsakaUniversity)
Construction of bounded confidence intervals for logistic response curves•

Toshiyuki Sato (Daiichi Pharmaceutical Co., Ltd.) and Masashi Goto (Osaka University)
Multi-level models and its applications•

Masanori Ito, Takashi Daimon, Tomoyuki Sugimoto and Masashi Goto (Osaka University)
Nonparametric diagnosis of the power transformation

11:00 – 11:10

Closing
Namio Ueno (Chair of JSCS, Osaka Gas Information System Research Institute Co., Ltd.)

11:30 – 12:30

ICNCB Key-note Lecture 3
Chair: Masashi Goto (Osaka University)•Byron Wm. Brown, Jr.* and Jerry Halpern (Stanford University, USA)
Sample sizes of clinical trials: for science and decision making

Rooms at the Conference
MO Hall (3rd floor): ICNCB Key-note lectures, Invited Sessions and Contributed Session 6
Conference Room 3 (2nd floor): ICNCB Contributed Sessions 1-5 and 7
Conference Room 2 (2nd floor): JSCS 15th Symposium (Language is Japanese)The participant of ICNCB can also take part in JSCS 15th Symposium freely.
Conference Room 1 (1st floor): Registration, demonstration, coffee or tea, Internet and so on
Lounge: Something to drinks will be prepared. There are vending machines for drinks here.

Directions to Osaka University Suita Campus
See also the ICNCB Information Bulletin.
Free Pick-up Bus From Senri Hankyu Hotel
During the conference, a free pick-up bus that connects Senri Hankyu Hotel and the conference venue (OsakaUniversity Convention Center) will be available. Participants are recommended to get to Senri-Chuo Station, walkabout 5 minutes to Senri Hankyu Hotel, and take the pick-up bus.
Departure Time Schedule
Senri Hankyu Hotel -> Convention Center: August 30, 11:00 / August 31, 9:00 / September 1, 9:00
Convention Center -> Senri Hankyu Hotel: August 30, 20:00 / August 31, 17:30 / September 1, 14:00

Public Transportation to the Conference Venue
Participants can mainly take Subway Midosuji Line (through Kita-Osaka Express Railway) and Osaka
Monorail to Senri-Chuo Station, and can take Hankyu Bus or taxi from Senri-Chuo the conference venue.
From Senri-Chuo Station (Kita-Osaka Express and Osaka Monorail)
From here take Hankyu Bus bound for “Handai Honbu-mae” (Osaka University Administration Bureau) or“Ibaraki Mihogaoka” (bus stop No. 6) and get off at “Handai Honbu-mae” (every 10 minutes, about 20 minutes
required, ¥210). It takes 5 minutes on foot from the “Handai Honbu-mae” bus stop to the conference venue.
Access from Main Transportation Terminals to Senri-Chuo Station
From Kansai International Airport• Take an airport limousine bound for “Osaka Station” and get off at “Hotel New Hankyu”. From here walk about 5minutes to the subway Umeda Station. Take Subway Midosuji Line (through Kita-Osaka Express Railway) in thedirection of Senri-Chuo Station (every 4-8 minutes, 19 minutes required, ¥350)• Take “Airport Rapid Service” of JR and get off at JR “Osaka” Station. From here walk about 5 minutes to thesubway Umeda Station. Take Subway Midosuji Line in the direction of Senri-Chuo Station.
• Take the Limited Express “Haruka” of JR. Trains departing from Kansai-International Airport take approximately
45 minutes to get to Shin-Osaka Station (Regular fare ¥2,980, Green Car fare ¥3,710). From here, transfer toSubway Midosuji Line and take in the direction of Senri-Chuo Station.
• Take the Limited Express “Rapi:t ” or Airport Express of Nankai Electric Railways and get off at Namba Station.
From here, transfer to Subway Midosuji Line and take in the direction of Senri-Chuo Station.
• Take an airport limousine bound for Osaka (Itami) Airport (80 minutes required, ¥1,700). From here, transfer toOsaka Monorail and get off at Senri-Chuo Station (13 minutes required, ¥320). You can also take a taxi from Itami
Airport to Senri Hankyu Hotel (20 minutes required, approx. ¥2,000).

From Shin-Osaka Station:
From here take Subway Midosuji Line and get off at Senri-Chuo station (15 minutes required, ¥320).
From JR Osaka (or Umeda) Station
From here take Subway Midosuji Line and get off at Senri-Chuo station (19 minutes required, ¥350).

Contact Address
Office of the 15th Symposium of JSCS (ICNCB Office)Wataru SAKAMOTO and Tomoyuki SUGIMOTO
Division of Mathematical Science, Graduate School of Engineering Science, Osaka University
1-3 Machikaneyama-cho, Toyonaka, Osaka 560-8531, Japan
Phone: +81-6-6850-6482, +81-6-6850-6486 Fax: +81-6-6850-6496
E-mail: sympo15@jscs.or.jp [URL] http://www.jscs.or.jp/taikai/sympo15/