No. DEFC0511

DEHYDRATED SOLVENT FM

Date of issue : 3 Jun. 2020
Date of revision : 28 Jul. 2023
Safety Data Sheet

1.

Product and company identification

Product name

: DEHYDRATED SOLVENT FMPart No.

: D312136-1

Name of manufacturer

2.

: HIRANUMA Co., Ltd.

Address: 1739 Motoyoshida, Mito, Ibaraki, 310-0836, JAPANName of section: Quality assurance department

Telephone number: +81-29-247-7343

Facsimile number: +81-29-240-0381

Mail address: info-f2@hiranuma.com

Summary of danger and Hazard

GHS classification
Physical and chemical hazard
Flammable liquids ：Category 3
Human health hazard
Acute toxicity (oral)：Category 4
Serious eye damage/eye irritation：Category 2ACarcinogenicity：Category 2

Reproductive toxicity：Category 1BSpecific target organ toxicity (single exposure)：Category 1 (central nervous system, visual organs, systemic
toxicity),
Category 3 (narcosis)
Specific target organ toxicity (repeated exposure)：Category 1 (central nervous system, visual organs)Category 2 (reproductive organs (male))
Pictograms or symbols－ 1/11 －No. DEFC0511

DEHYDRATED SOLVENT FM

Signal word

：Danger

Hazard statements：Flammable liquid and vapor
Harmful if swallowed
Causes serious eye irritation
May cause drowsiness and dizziness
Suspected of causing cancer
May damage fertility or the unborn childCauses damage to organs (central nervous system, visualorgans, systemic toxicity)
Causes damage to organs (central nervous system, visualorgans) through prolonged or repeated exposure
May causes damage to organs (reproductive organs (male))through prolonged or repeated exposure

Precautionary statements
Prevention：Do not handle until all safety precautions have been read andunderstood.
Keep away from heat, hot surfaces, sparks, open flames andother ignition sources. No smoking.
Keep container tightly closed.
Ground and bond container and receiving equipment.
Use explosion-proof electrical/ventilating/lighting equipment.
Use only non-sparking tools.
Take action to prevent static discharges.
Do not breathe mist/vapors.
Wash hands, forearms and face thoroughly after handling.
Do not eat, drink or smoke when using this product.
Use only outdoors or in a well-ventilated area.
Wear protective gloves/protective clothing/eye protection/faceprotection.

Response：IF SWALLOWED: Call a POISON CENTER or doctor if you feelunwell.
IF ON SKIN (or hair): Take off immediately all contaminatedclothing. Rinse skin with water.
IF INHALED: Remove person to fresh air and keep comfortable－ 2/11 －No. DEFC0511

DEHYDRATED SOLVENT FM

for breathing.
IF IN EYES: Rinse cautiously with water for several minutes.
Remove contact lenses, if present and easy to do. Continue
rinsing.
IF exposed or concerned: Call a POISON CENTER or doctor.
IF exposed or concerned: Get medical advice/attention.
Call a POISON CENTER or doctor if you feel unwell.
Get medical advice/attention if you feel unwell.
Rinse mouth.
If eye irritation persists: Get medical advice/attention.
Storage：Store in a well-ventilated place. Keep container tightly closed.
Store in a well-ventilated place. Keep cool.
Store locked up.

Disposal：Dispose of contents/container to hazardous or special waste
collection point, in accordance with local, regional, national
and/or international regulation.

3.

Composition/Information on ingredients

Distinction of substance or mixture：Mixture
ChemicalConcentration

name

(%)

Formamide
Methanol4.

Formula

TSCA

EC-No.

CAS RN74

HCONH2

Listed200-842-0

75-12-7

26

CH3OH

Listed200-659-6

67-56-1

First aid measures

Inhalation：Remove the victim to fresh air, and make him blow his noseand gargle.

Skin contact：Wash the affected areas under running water.

Eye contact：Wash the affected areas under running water for at least 15
minutes. If necessary, get medical treatment.

Ingestion：The chemical is volatile. Do not induce vomiting because it
increases the risk of aspiration into the lungs. Get medical
attention immediately. If necessary, rinse mouth with water.

Personal Protection in First Aid and Measures：Rescuers should wear proper protective equipment like rubber
gloves, goggles.
－ 3/11 －No. DEFC0511

5.

DEHYDRATED SOLVENT FM

Fire fighting measures

Extinguishing media：Water, dry chemical powder, carbon dioxide, dry sand,alcohol resistant foam

Prohibited extinguishing media：Foam extinguisher
Particular fire fighting：Move containers from fire area if it can be done without risk,
if not possible, apply water from a safe distance to cool andprotect surrounding area.
Dry chemical powder, carbon dioxide or dry sand should be
used for small fires. Alcohol-resistant foam extinguisher iseffective for a large scale fire.
Protection for firefighters：Wear breathing apparatus.

6.

Accidental release measures

Cautions for personnel：Wear proper protective equipment and avoid contact with skinand inhalation of vapor. Conduct operations from upwind andevacuate people downwind. Remove all sources of ignition.
Keep away personnel except for authorized ones fromspillage area by stretching ropes.
Cautions for environment：Attention should be given to avoid discharge of spilled productinto rivers and resulting environmental damage. When diluting
spill with large amounts of water, discharge of untreatedwastewater into the environment must be avoided.
Methods and Equipment for Containment and Cleaning up
For containment：Absorb spill with inert material (e.g., diatomaceous earth, sand)and flush spillage area with copious amounts of water.

Prevention of second accident：Remove nearby sources of ignition and prepare extinguishingmedia.

7.

Cautions of handling and storage

Handling－ 4/11 －No. DEFC0511

DEHYDRATED SOLVENT FM

Technical measures：Wear proper equipment to avoid contact with skin or inhalationof vapor. Fire is strictly prohibited.
Ventilate well at working places.
Cautions for safety handling：Use with an enclosed system or a local exhaust ventilation. Use
in well-ventilated areas.
Do not allow contact with oxidizing substances.
Storage
Adequate storage condition：Store in a dark, cool place and tightly closed.
Safety adequate container materials：Glass, fluorine resin, stainless steel
Do not use vinyl chloride resin, acrylic resin, polystyrene etc.

8.

Exposure control/Personal protection
Formamide

ACGIH TWA：10ppm
Remark（ACGIH）：Skin

Methanol

ACGIH TWA：200ppm
ACGIH STEL：250ppm
Remark（ACGIH）：Skin

Engineering measures：Use with an enclosed system or a local exhaust ventilation.
Protective equipment
Respiration protective equipment：Chemical cartridge respirator with an organic vapor cartage orairline respirator
Hands protective equipment：Impervious protective gloves
Eyes protective equipment：Safety goggles
Skin and body protective equipment：Protective clothing, protective boots9.

Physical and chemical properties

Appearance：Liquid

Color：Colorless－ 5/11 －No. DEFC0511

DEHYDRATED SOLVENT FM

Odor：Characteristic odorpH

：No data available

Melting point：-97.49 °C (as methanol)

Freezing point：No data available

Boiling point：64.51 °C (as methanol)

Flash point：33 °C

Auto-ignition temperature：470 °C (as methanol)
Decomposition temperature：No data available
Flammability：Flammable

Vapor pressure：128 hPa (20 °C) (as methanol)

Relative density：No data available

Density：Approx. 1.0 g/cm³ (20 °C)

Relative gas density ：1.1 (as methanol)
Solubility：Water：Miscible.
Organic solvents：Miscible with many kinds of organic solvents
like ethanol, diethyl ether.

Partition coefficient n-octanol/water (Log Pow)
：No data available
Explosive limits (vol %)：6.0 – 36.5 vol % (as methanol)
Viscosity, kinematic:：No data available

Particle characteristics：No data available

10. Stability and reactivity
Reactivity：May react with oxidizing substances.

Chemical stability：Stable under normal conditions.

Possibility of hazardous reactions：Stable under normal conditions of use.
Conditions to avoid：Light, heat.

Incompatible materials ：Oxidizing substances.
Hazardous decomposition products：Carbon monoxide, nitrogen oxides, hydrogen cyanide.

11. Toxicological information－ 6/11 －No. DEFC0511

DEHYDRATED SOLVENT FM

Acute toxicity (oral) ：Harmful if swallowed
ATEmix=1331 mg/kg
Acute toxicity (dermal)：No classification
ATEmix>2000 mg/kg
Acute toxicity (inhalation)：No classification (gas)Classification not possible (vapor)
Classification not possible (dust, mist)
Skin corrosion/irritation：Classification not possible
Serious eye damage/eye irritation：Causes serious eye irritation
The product contains methanol (category 2A) and wasclassified as category 2A based on its content.
Methanol：In a rabbit Draize test, mean scores of conjunctivitis
were judged to be 2 and higher (2.1) at 24, 48 and 72-hour
after installation. Chemosis (score of 2.00) observed up to
4-hour had decreased significantly by 72-hour (score of 0.50).
Since it is not clear whether the effects reversed within 7days, sub-categorization was not performed. Based on thedata, the substance was classified into category 2A.
Respiratory sensitization：Classification not possible
Skin sensitization：Classification not possible

Germ cell mutagenicity：Classification not possible
Carcinogenicity：Suspected of causing cancer
The product contains formamide (category 2) and wasclassified as category 2 based on its content.
Formamide：ACGIH classifies it as the group A3 (confirmed
animal carcinogen with unknown relevance to humans).

Reproductive toxicity：May damage fertility or the unborn child
The product contains formamide (category 1B) and methanol(category 1B) and was classified as category 1B based on
their content.
Formamide：There is a report that in a continuous breeding
study with mice by the oral route, fertility effects were－ 7/11 －No. DEFC0511

DEHYDRATED SOLVENT FM

observed at a dose where parental toxicity. There is a reportthat in a teratogenicity test with mice by the oral route,skeletal malformations were observed in fetuses at a dose
where no maternal toxicity was observed. From the above, it
was classified into category 1B.
Methanol：In a developmental toxicity test by inhalation
exposure to mice during organogenesis period, fetal resorptions
and exencephaly were observed. Additionally, similar effects
including cleft palate were reported in other inhalation and oral
exposure tests. For effects of methanol on reproduction,scientific decisions concerning health risks are generally basedon what is known as weight-of-evidence approach. Recognizing
the lack of human data and the clear evidence of laboratory
animal effects, it was concluded that methanol may adversely
affect human development if exposures are sufficiently high.
Based on the information, the substance was considered to bea presumed human reproductive toxicant and it was classified
into category 1B.
Specific target organ toxicity (single exposure)：Cause damage to organs (central nervous system, visualorgans, systematic toxicity)
May cause drowsiness and dizziness
The product contains methanol (category 1, category 3) andformamide (category 3), and based on their content, was classified
as category 1 (central nervous system, visual organs, systemic
toxicity) and category 3 (narcosis).
Methanol：The symptoms of acute poisoning from the substanceinclude CNS-depression. Formate accumulates in the blood during alatency period which leads to metabolic acidosis, visual impairment
or even total blindness, headaches, dizziness, nausea, vomiting,Kussmaul breathing and coma. In some cases death is the final
outcome. Further, CNS disorders, especially parkinsonism-likeextrapyramidal symptoms were reported. Morphological changes,
necrosis in the white substance of the brain were demonstrated.
Based on the human information, the substance was classified into
category 1 (central nervous system). Additionally, the eye wasregarded as a target organ since visual impairment is acharacteristic effect. Additionally, systemic toxicity is regarded as－ 8/11 －No. DEFC0511

DEHYDRATED SOLVENT FMa target organ based on the reports of headache, nausea, vomiting,tachypnea and coma as signs of metabolic acidosis. The effects ofsingle exposures by inhalation include narcosis. As an acute toxicity
in humans, a narcotic effect results from central nervous systemdepression. Based on the data, the substance was classified into
category 3 (narcosis).
Formamide：In a single inhalation exposure test using rats,
symptoms of “lethargy, hunchback posture, clear or red eyedischarge, red nasal discharge, partially closed eyes, diarrhea, andbrown staining of the lower abdomen” were observed at doses of
14-21 mg/L. It is reported that the symptoms almost disappearedon the 8th day after exposure. Based on the above, it wasclassified into category 3 (narcosis).
Specific target organ toxicity (repeated exposure)：Cause damage to organs (central nervous system, visualorgans) through prolonged or repeated exposure
May cause damage to organs (reproductive organs (male)) throughprolonged or repeated exposure
The product contains methanol (category 1) and formamide(category 2), and was classified as category 1 (central
nervous system, visual organs) and category 2 (reproductive
organs (male)) based on their content.
Methanol：Based on a report that the most noted healthconsequence of longer-term exposure to lower levels of methanol
is a broad range of ocular effects, and that cases of chronic
poisoning from occupational exposure to methanol were manifested
by bilateral blindness, it was classified into category 1 (visualorgans). Additionally, based on the report that cases of chronic
poisoning from repeated exposure to methanol vapour are
manifested by headache, giddiness, insomnia, and gastricdisturbances, it was classified into category 1 (central nervous
system).
Formamide：In a 2-year combined chronic toxicity/carcinogenicity
study by oral gavage in rats and mice, hyperplasia of bone marrowin rats, calcification of testicular arteries and sheath of testis andspleen in mice at 80 mg/kg/day. It has been reported that
hematopoietic cell proliferation was observed. There is also areport that blood effects were observed at 300 mg/kg/day in－ 9/11 －No. DEFC0511

DEHYDRATED SOLVENT FM

two 90-day repeated dermal administration studies using rats.
Furthermore, in a 2-week repeated inhalation exposure test using
rats, it was reported that platelet count decreased at 500ppm or
more, and kidney effects and testicular degeneration wereobserved at 1500ppm. Based on the above, the substance wasclassified into category 2 (reproductive organs (male)) because
effects on testis were observed within the dose range of category2.
Aspiration hazard：Classification not possible

12. Ecological information
Ecotoxicity
Aquatic acute：No classification
Methanol： Crangon crangon LC50=1340 mg/L/96h
Formamide： Pseudokirchneriella subcapitata
ErC50>1000 mg/L/72h

Aquatic chronic：No classification

Persistence and degradability：No additional information available
Bioaccumulative potential：No additional information available
Mobility in soil

：No additional information available

Hazardous to the ozone layer：Classification not possible

13. Disposal consideration
Residual disposal：Burn in a chemical incinerator equipped with an afterburner anda scrubber. Or entrust approved waste disposal companies withthe disposal.

Containers：In case of disposal of empty bottles, dispose bottles after
removing the content thoroughly.

14. Transport information
International Regulations
Transport by sea (IMDG)
UN-No. (IMDG)：1992

Proper Shipping Name (IMDG)－ 10/11 －No. DEFC0511

DEHYDRATED SOLVENT FM：FLAMMABLE LIQUID, TOXIC, N.O.S. (formamide, methanol,
solution)
Packing group (IMDG)：III
Transport hazard class(es) (IMDG)：3(6.1)
Air transport (IATA)
UN-No. (IATA)：1992

Proper Shipping Name (IATA)：Flammable liquid,toxic, n.o.s. (formamide, methanol, solution)
Packing group (IATA)：III
Transport hazard class(es) (IATA)：3(6.1)Marine pollutant：Not applicable

Transport in bulk according to Annex II of MARPOL 73/78 and the IBC Code
Pollutant category：Y

MFAG-No.

：131

15. Regulatory information
Regulatory information with regard to this substance in yourcountry or region should be examined by your own
responsibility.

16. Other information
References
1) Company data on file.
2) NITE Chemical Risk Information Platform (NITE CHRIP), National Institute ofTechnology and Evaluation.
＊The information contained herein is based on several references and the present state of ourknowledge. However the SDS does not always cover all information about the product, handle
the product carefully. The information is intended to ordinary usage, in case of particular
handlings, conduct appropriate safety measurements. The information herein is only provision of
information, and it does not represent a guarantee the properties of the product. The Safety
Data Sheet (SDS) is prepared based on JIS Z7253.

－ 11/11 －