BIOTECHABS(Derwent Biotechnology Abstracts)
Subject
Coverage

•
•
•
•
•
•
•
•
•
•
•
•
•
•
•

Agriculture
Biocatalysis
Biochemical Engineering
BIOINFORMATICS methodologies, databases, hardware and software
Cell Culture
Chemistry: Physicochemical and Biological Assays relevant to Biotechnological
Processes
Downstream Processing
Food Additives and SCP
Fuels produced by Fermentation or Similar Processes
GENOMICS and PROTEOMICS, including pharmacogenomics, expression profiling,
ESTs and SNPs, and high throughput screening
Microbiology: Genetics and Fermentation
Other Chemicals produced by Microorganisms and Enzymatic Synthesis
Pharmaceuticals produced by Microorganisms and Enzymatic Synthesis
Tissue culture and engineering products, processes and applications
Waste Disposal

File Type

Bibliographic

Features

Thesaurus

Controlled Term (/CT)

Alerts (SDIs)

Not available

CAS Registry
Number® IdentifiersKeep & Share

Learning Database

SLART
Structures

RecordContent• Records contain bibliographic information, Derwent's abstract and controlled indexing.
• For the file crossover to DWPI, the Derwent Accession Number is available in all
patent records.

File Size• 479,398 citations

Coverage

1982-2010

Updates

Static File

Language

English

Database
Producer

Clarivate
Friars House, 160 Black Friars Rd.
London SE1 8EZ
United Kingdom
Copyright Holder: Clarivate

August 2023

2
BIOTECHABS

Sources• Journals• Patents• Conference contributions

User Aids• Online Helps (HELP DIRECTORY lists all help messages available)• STNGUIDE

Cluster• ALLBIB• AUTHORS• BIOSCIENCE• CHEMENG• CORPSOURCESTN Database Cluster information:
https://www.cas.org/support/training/stn/database-clusters

August 2023

3
BIOTECHABS

Search and Display Field Codes
General Search Fields
Search Field Name

SearchCode

Display
Codes

Search Examples

Basic Index (contains single
words from title (TI), abstract(AB), and controlled term (CT),as well as enzyme commission
numbers (EC))

None
or
/BI

S PRODUCTION OF CARBOCYCLIC
NUCLEOSIDES

Accession Number
Application Country(WIPO code and text)
Application Date (1)Application Number (2)

/AN
/AC

S 1992-14434/AN
S EP/AC(S)1992/AY

AN
AI

/AD
/AP

AI
AI

Application Year (1)Author/AY/AU

Classification Code(code and/or text)
Controlled Term (3)Corporate Source (3)/CC(or /CCEN)/CT/CS

Document Type(code and text)/DT(or /TC)

Entry Date (1)/ED(or /UP)/EC/ISN

S EP/AC(S)20 FEB 1992/AD
S 1992EP-0250036/AP
S EP1992-250036/AP
S 1991-1992/AY(S)FR/ACS BAINES B S/AU
S BAINES, B S/AU
S K/CC AND GLAXO/CSS LIPASE NOT BIOCATALYSIS/CCS SOIL DECONTAMINATION/CT
S GRANADA-GENET?/CS
S "GRANADA-GENET."/CS
S K/CC AND P/DT
S JOURNAL/DT AND SOIL
DECONTAMINATION/CT
S ED>FEB 2009
S EC-3.1.1.3/EC AND US/PCS EMTED2/ISN
S 1001-0742/ISN

TI,AB,CT,EC
ISN, SOS DNA CELL BIOL./JT
S DE/LA AND L10
S L7 AND ENGLISH/LAS GLAXO RESEARCH/LO
S 1992-333672/OS
S PREUSSAG/PA
S PROTEIN-DESIGN-LABS/PA
S EP/PC(S)1992/PY
S UNITED KINGDOM/PCS EP-507421/PN
S EP507421/PN
S EP0507421/PN
S BE/PRC(S)1991/PRY
S UNITED STATES/PRC
S 18 FEB 1991/PRD
S MARCH 1992/PRDF(S)JP/PRC
S 1991EP-0200379/PRN
S EP1991-200379/PRN
S 1990-1991/PRY
S 1990-1991/PRYF(S)BE/PRC
S 7 OCT 1992/PD(S)EP/PC
S 1990-1991/PY(L)EMTED2/SO
S ENZYME MICROB/SO
S (DECHEMA(S)CONF?)/SO

JT, SOLAS DECONTAMINATION OF SOIL/TI

TI

Enzyme Commission Number
International (Standard)
Document Number (contains
CODEN and ISSN)
Journal Title
Language (ISO code and text)

/JT
/LA

Location (4)Other Source (5)Patent Assignee (3)

/LO
/OS
/PA

Patent Country(WIPO code and text)
Patent Number (2)/PC

Priority Country(WIPO code and text)
Priority Date (1)Priority Date First (1)Priority Number (2)/PRC

Priority Year (1)Priority Year, First (1)Publication Date (1)Publication Year (1)Source (contains journal title,
CODEN, ISSN, collation andmeeting information)
Title

/PRY
/PRYF
/PD
/PY
/SO

/PN

/PRD
/PRDF
/PRN

/TI

TI, AB, CT, EC

S EC-3.1.1.3
S LIPASE(L)CARBOXYLESTERASE

AI
AU
CC

CS
DT

ED

LO
OS
PA
PI
PI

PRAI
PRAI
PRAI
PRAI
PRAI
PRAI
PI
PI, PY, SO
SO

August 2023

4
BIOTECHABS(1) Numeric search field that may be searched using numeric operators or ranges.
(2) Either STN or Derwent format may be used.
(3) Search with implied (S) proximity is available in this field.
(4) Search with implied (L) proximity is available in this field.
(5) Contains the WPIDS/WPIX/WPINDEX accession number.

Controlled Term (/CT) Thesaurus
All Relationship Codes can be used with both the SEARCH and EXPAND command.
Code
ALL
AUTO (1)
BT
HIE
KT
NT
PFT
RT
STD
USE

Content

ExamplesAll Associated Terms (BT, SELF, USE, UF, EXA, TNA,
SNA, EC, RT, OLD, NEW, NT, KT)
Automatic Relationship (SELF, USE, UF, OLD, NEW, TNA,
SNA, EC)
Broader Terms (also BT1=1st level, BT2=2nd level etc.)
Hierarchy Terms (all broader and narrower terms) (BT,SELF, NT)
Keyword Terms (KT, SELF)
Narrower Terms (also NT1=1st level, NT2=2nd level etc.)
Forbidden and Preferred Terms (SELF, USE, UF)
Related Terms (SELF, RT)
Standard Terms (BT, SELF, NT, RT)
Preferred Terms (SELF, USE)

E FUNGICIDE+ALL/CTS FERMENTER+AUTO/CT
E BENOMYL+BT/CT
E PROTEASE+HIE/CT
E ENZYME+KT/CT
S FUNGICIDE+NT/CT
S ANTIFUNGAL+PFT/CT
E PESTICIDE+RT/CT
E DINOSEB+STD/CTS FERMENTER+USE/CT(1) Automatic Relationship is SET OFF. In case of SET REL ON the result of EXPAND or SEARCH without any relationship code is thesame as described for AUTO.

DISPLAY and PRINT Formats
Any combination of formats may be used to display or print answers. Multiple codes must be separated by
spaces or commas, e.g., D L1 1-5 TI PI. The fields are displayed or printed in the order requested.
Hit-term highlighting is available for all fields. Highlighting must be ON during SEARCH to use the HIT, KWIC,
and OCC formats.

FormatAB
AI (AP) (1)AN
AUCC (CCEN)
CSCT
DT (TC)EC (2)ISN (2)JT (2)LA
LO
OS
PA
PI (PN) (1)August 2023

Content

ExamplesAbstract
Application Information
Accession Number
AuthorClassification Code (code and/or text)
Corporate Source
Controlled Term
Document Type
Enzyme Commission Number
International (Standard) Document Number
Journal Title
Language
Location
Other Source
Patent Assignee
Patent Information

D TI AB
D AI
D AN
D AU
D CC
D AU CS
D CT
D DT
D EC
D ISN
D JT
D LA
D LO
D OS
D PA TI 1-10
D PI PRAI

5
BIOTECHABSDISPLAY and PRINT Formats (cont'd)FormatContent

Examples

PRAI (PRN) (1)PY (2)
SO
TI
ABS
ALL
DALL
IALL
BIB
IBIB
IND
SCAN (3)
TRIAL (TRI, SAM)

Priority Information
Publication Year
SourceTitle
AN, ABAN, TI, AU, CS, PA, LO, SO, PI, AI, PRAI, DT, LA, OS, AB, CC, CT
ALL, delimited for post processing
ALL, indented with text labels
AN, TI, AU, CS, PA, LO, SO, PI, AI, PRAI, DT, LA, OS (default)
BIB, indented with text labels
AN, CC, CT
AN, TI
AN, TI, CC, CT

D PRAI
D PY
D SO
D TI CT
D TI ABS 1-5
DIS ALLD DALLD IALL 1-3 L4
D BIB ABS
D IBIB KW
D IND
D SCAND TRI 1-10

HIT
KWIC
OCC

Hit term(s) and field(s)Hit term(s) plus 20 words before and after hit term(s) (KeyWord-In-Context)
Number of occurrences of hit term(s) and field(s) in which they occur

D HIT
D KWICDOCC(1) Application, priority and patent numbers are available in Derwent and STN format. The format for DISPLAY, PRINT, SELECT and
SORT is controlled by the Messenger SET PATENT command. The STN format is default. 'SET PAT DERWENT' changes(permanently) to the Derwent format. To change to the STN format again, enter 'SET PAT STN'.
(2) Custom display only.
(3) SCAN must be specified on the command line, i.e., D SCAN or DISPLAY SCAN.

SELECT, ANALYZE, and SORT Fields
The SELECT command is used to create E-numbers containing terms taken from the specified field in ananswer set.
The ANALYZE command is used to create an L-number containing terms taken from the specified field in ananswer set.
The SORT command is used to rearrange the search results in either alphabetic or numeric order of thespecified field(s).

Field Name
Abstract
Accession Number
Application Country
Application Date
Application Number
Application Year
AuthorClassification Code (code and/or text)
CODEN
Controlled Term
Corporate Source
Document Type

Field Code
AB
AN
AC
AD
AP (AI)
AY
AU
CC (CCEN)
CODEN
CT
CS
DT (CT)ANALYZE/
SELECT (1)
Y (2)
Y
Y
Y
Y
Y
Y
Y
N
Y
Y
Y

SORT
N
N
Y
Y
Y
Y
Y
N
Y
N
Y
Y

August 2023

6
BIOTECHABSSELECT, ANALYZE, and SORT Fields (cont'd)
Field Name
Enzyme Commission Number
International (Standard) Document Number
Journal Title
Language
Location
Occurrence Count of Hit Terms
Other Source (DWPI accession number)
Patent Assignee
Patent Country
Patent Number
Priority Country
Priority Date
Priority Date First
Priority Number
Priority Year First
Publication Date
Publication Year
SourceTitle

Field Code
EC
ISN
JT
LA
LO
OCC
OS
PA
PC
PN (PI)
PRC
PRD
PRDF
PRN (PRAI)
PRYF
PD
PY
SO
TI

ANALYZE/
SELECT (1)

SORT

Y
Y (3)
Y
Y
Y
N
Y
Y
Y
Y
Y
Y
Y
Y
Y
Y
Y
Y (4)
Y (default)

Y
Y
Y
Y
Y
Y
Y
Y
Y
Y
Y
Y
Y
Y
Y
Y
Y
N
Y

(1) HIT may be used to restrict terms extracted to terms that match the search expression used to create the answer set, e.g., SEL HIT
AU.
(2) Appends /BI to the terms created by SELECT.
(3) Selects or analyzes ISSN and CODEN with /ISN appended to the terms created by SELECT.
(4) Selects or analyzes ISSN and CODEN with /SO appended to the terms created by SELECT.

Sample Records
DISPLAY ALL
AN
1997-06228 BIOTECHABS
TI
Purification, characterization, and properties of two xylanases from
Humicola insolens;endo-1,4-beta-D-xylanase isoenzyme isolation
AU
Dusterhoft E M; Linssen V A J M; Voragen A G J; Beldman G
CS
Univ.Wageningen-Agr.
LO
Department of Food Chemistry and Microbiology, Wageningen Agricultural
University, P.O. Box 8129, 6700 EV Wageningen, The Netherlands.
SO
Enzyme Microb.Technol.; (1997) 20, 6, 437-45
CODEN: EMTED2
ISSN: 0141-0229
DT
JournalLA
EnglishAB
Two endo-1,4-beta-D-xylanases (EC-3.2.1.8), xyl1 and xyl2, were purified
from a commercial enzyme preparation derived from Humicola insolens byanion-exchange chromatography, size-exclusion chromatography and cationexchange chromatography. The homogenous proteins had a mol.weight of
6,000 and 21,000, and isoelectric points of 9.0 and 7.7 for xyl1 and xyl2,
respectively. Both enzymes had similar pH and temperature optima (pH 66.5 and 55-60 deg), but their stability at various pH and temperature
differed. The molar activity towards beech, birch and larch xylan, andwheat arabinoxylans was higher for xyl2. Both enzymes had remarkably
lower molar activities toward the insoluble fractions of these xylans or
toward the essentially insoluble beech xylan, but the decrease was lesspronounced with xyl2. This might be explained by differences in specificadsorption, with xyl2 adsorbing strongly on beech xylan. In contrast to
August 2023

7
BIOTECHABS

CCCT

xyl1, xyl2 was markedly inhibited by a number of metal ions. The reaction
products formed during hydrolysis of different xylans and the end products
were the same for both enzymes, but their relative proportions differedslightly. (34 ref)K BIOCATALYSIS; K1 Isolation and Characterization
HUMICOLA INSOLENS ENDO-1,4-BETA-D-XYLANASE ISOENZYME PURIFICATION,
CHARACTERIZATION FUNGUS ENZYME EC-3.2.1.8 (VOL.16, NO.11)

DISPLAY IBIBACCESSION NUMBER: 2001-00753 BIOTECHABS
TITLE:
Microalgae: a green source of renewable H2;
recent advances in algal hydrogen production using e.g.
Chlamydomonas reinhardtii; a review
AUTHOR:
Ghirardi M L; Zhang L; Lee J W; Flynn T; Seibert M; Greenbaum
E; *Melis A
CORPORATE SOURCE: Nat.Renewable-Energy-Lab.Colorado; Univ.California;
Oak-Ridge-Nat.Lab.
LOCATION:
University of California, Berkeley, CA 94720-3102, USA.
Email: melis@nature.berkely.edu
SOURCE:
Trends Biotechnol.; (2000) 18, 12, 506-11
CODEN: TRBIDM
ISSN: 0167-9430
DOCUMENT TYPE:
JournalLANGUAGE:
EnglishDISPLAY ALL (Derwent format)
AN1997-04239 BIOTECHABS
TI
Crystallization of macromolecules;
e.g. nucleic acid crystallization method
AU
Fibi M
PA
Behringwerke
LO
Marburg, Germany.
PI
EP----757057 5 Feb 1997
AI
1996EP-0110784 4 Jul 1996
PRAI 1995DE-1028507 3 Aug 1995
DT
PatentLA
GermanOS
WPI: 1997-121141 [12]AB
Macromolecules such as glycoproteins and nucleic acids are crystallized in
the presence of a 4-(1-18C alkyl)-umbelliferone salt (A). In a preferred
process, (A) is 4-methylumbelliferone sodium salt. A solution containing
the macromolecule at 0.1-10,000 ug/ml is mixed at a ratio of 1000:1 to
1:1000 with a solution of 0.1-1,000 mM (A), and the mixture is incubatedat 0-25 deg. The macromolecule solution is preferably a phosphate buffer
solution (pH 3-9) containing 1-500 mM (A), provided that the concentrationof (A) in the macromolecule solution is less than that in the
crystallization solution. The crystallized macromolecules may be used for
X-ray structural analysis, as a pharmaceutical or as seed crystals. (4pp)
CC
A GENETIC ENGINEERING AND FERMENTATION; A1 Nucleic Acid Technology
CT
MACROMOLECULE E.G. NUCLEIC ACID CRYSTALLIZATION METHOD (VOL.16, NO.8)

August 2023

8
BIOTECHABSEXPAND in CT THESAURUS=> e fungicide+all/ct
E115381
BT1 ANTIBIOTIC/CT
E2932
BT2 AGRICULTURE/CT
E39736
BT1 pesticide/CT
E44165--> FUNGICIDE/CT
E5
22UF
antifungal/CT
E6
591
UF
antimicrobial/CTE7
5UF
antimycotic/CT
E8
3UF
fungistatic/CT
E953
NT1 AMPHOTERICIN/CT
E10
13
NT1 AZASERINE/CT
E11
17
NT1 BAFILOMYCIN/CT
E1253
NT1 BENOMYL/CT
E13
12
NT1 BLASTICIDIN-S/CT
E14
3
NT1 BUTALACTIN/CT
E15
2
NT1 DAPIRAMYCIN/CT
E16
1
NT1 DEHYDROIVAXILLIN/CT
E17
15
NT1 DINOSEB/CT
E18
17
NT1 EMODIN/CT
E19
18
NT1 GRISEOFULVIN/CT
E20
62
NT1 ITURIN/CT
E21
4
NT1 LYDICAMYCIN/CT
E22
8
NT1 METALAXYL/CT
E23
79
NT1 NIKKOMYCIN/CT
E24
1
NT1 NITROSOFUNGIN/CT
E25
54
NT1 NYSTATIN/CT
E26
32
NT1 OLIGOMYCIN/CT
E27
450
NT1 PENTACHLOROPHENOL/CT
E28
13
NT1 SINEFUNGIN/CT
E29
0NT1 VIRIDOFULVIN/CT
E30
0KT
FUNGICIDE RESISTANCE/CT********** END **********In North America

In Europe

In Japan

CAS Customer Center:
P.O. Box 3012
Columbus, Ohio 43210-0012
U.S.A.

CAS Customer Center EMEA
(represented by FIZ Karlsruhe)
P.O. Box 2465
76012 Karlsruhe
Germany

JAICI (Japan Association forInternational Chemical Information)
Nakai Building
6-25-4 Honkomagome, Bunkyo-ku
Tokyo 113-0021
Japan

Phone:
E-mail:Internet:

800-753-4227 (North America)
614-447-3731 (worldwide)
help@cas.org
www.cas.org

Phone:
E-mail:Internet:+49-7247-808-555
EMEAhelp@cas.org
www.stn-international.com

Phone:
E-mail:Internet:

August 2023

+81-3-5978-3601 (Technical Service)+81-3-5978-3621 (Customer Service)support@jaici.or.jp (Technical Service)customer@jaici.or.jp (Customer Service)www.jaici.or.jp