LIPIDS & BRAIN IV:
LIPIDS IN ALZHEIMER DISEASE
thth

Sunday 8 to Wednesday 11 October 2017

Nancy, France
https://lipidsandbrain.event.univ-lorraine.fr

Organizing Committee
Dr Philippe Guesnet, Pr Elmira Arab-Tehrany, Dr Bernadette Delplanque,
Dr Claire
Dr Ali Tamayol, Pr Jean-Luc Olivier, Pr Michel Linder
Société Française
pour Bourlieu,
l’Etude des Lipides
A non-governmental, non-profit scientific society founded in 1943
Organizing Committee: Dr Philippe Guesnet, Pr Elmira Arab-Tehrany, Dr Bernadette Delplanque,
Dr Claire Bourlieu, Dr Ali Tamayol, Dr Jean-Luc Olivier, Pr Michel Linder (President of SFEL)
Université de Lorraine – ENSAIA 2, avenue de la Forêt de Haye TSA 40602 54518 – VANDOEUVRE CEDEX
https://lipidsandbrain.event.univ-lorraine.fr/

The French Society for the Study of lipids (SFEL) is a non-governmental, non-profit
scientific society founded in 1943. Its main objective is to engage in all activities intended
to promote scientific interactions and collaborations between national and international
searchers from industry and academic in the field of lipids. For this purpose, our activity
is essentially directed toward organization of hot topic meetings “les Journées Chevreul”
each year and participation as co-editors as well as publications providers for thebimonthly OCL journal (Oilseeds and fats, Crops and Lipids, www.ocl-journal.org/), a
french peer-reviewed full Open-Access scientific journal devoted to fats and lipids.
Since 2007, the SFEL organize each 4 years an international conference held in Paris“Lipids & Brain Journées Chevreul” with the participation of several European scientificassociations (2007 DGF, 2011 Norway L&B, 2015 SCI). Over a period of 3 days, “Lipids &Brain” conferences examine the latest findings in this field of research from leading
researchers into both fundamental and applied research on the metabolism of FAs and
PUFAs within the brain and the retina, with a focus on neural pathologies. They provided
an opportunity to extend our knowledge in these fields of research and on therelationship between nutrition, FAs, lipids and central nervous system function during
development and ageing. They have also honoured with the French “CHEVREUL Medal”
Dr Stanley I. Rapoport (Bethesda, USA) and Pr. Nicolas G. Bazan (New Orleans, USA) andDr Crawford (London, UK) for their pioneering research.
Lipids & Brain conferences have now become a benchmark in this field of research,
the only one in Europe to date, and is backed by all international societies.
This year, only two years after the large success of the last one in 2015, we organize
in Lorraine University a special Lipid and Brain IV dedicated to “Lipids in Alzheimer
disease”. We will examine the latest findings in this world growing disease with theobjective is to assemble the medical community and the scientists and to improveconnections, discussions and exchanges between physicians, nutritionists andfundamental scientists, in an attempt to develop prevention and treatments of thishuman pathology. Moreover, the SFEL has decided to honour a scientist who dedicatedhis carrier to a very original research in this field: Pr Stephen Cunnane (Université
Sherbrooke, Canada) by the French Chevreul Medal 2017.

Société Française pour l’Etude des Lipides
A non-governmental, non-profit scientific society founded in 1943
Organizing Committee: Dr Philippe Guesnet, Pr Elmira Arab-Tehrany, Dr Bernadette Delplanque,
Dr Claire Bourlieu, Dr Ali Tamayol, Dr Jean-Luc Olivier, Pr Michel Linder (President of SFEL)
Université de Lorraine – ENSAIA 2, avenue de la Forêt de Haye TSA 40602 54518 – VANDOEUVRE CEDEX
https://lipidsandbrain.event.univ-lorraine.fr/

PROGRAM LIPIDS and BRAIN IV – LIPIDS IN ALZHEIMER DISEASE
Sunday, 8 October
16h00: Registration, Posters
17h00-19h00: Welcome reception
Monday, 9 October 20178h00 – 9h00 Registration

Session 1: Physiopathology, Epidemiology and Drug Therapy
9h00-9h45
Bruno DUBOIS. Université Pierre et Marie Curie, Paris 06, Institut de la Mémoire et de la Maladied’Alzheimer (IM2A) & Institut du Cerveau et de la Moelle épinière (ICM), Département de Neurologie,
Hôpital de la Pitié-Salpêtrière, Paris, France.
Title: The continuum of Alzheimer disease
9h45-10h15
Jean-François DARTIGUES. Bordeaux Population Health (BPH Center) INSERM U 897. Université deBordeaux, France.
Title: Alzheimer's Disease in the city
10h15 – 11h00

Coffee break / posters

11h00-11h30
George S. BLOOM. Department of Neuroscience, University of Virginia, Charlottesville, VA, USA.
Title: How Brain Insulin Resistance Contributes to Alzheimer’s Disease Pathogenesis
11h30-12h00
Philippe LEGRAND. Rennes, France. To be announced

12h00 14h00

LUNCH (restaurant hippodrome)

Session 2: Alzheimer Disease – Interaction with Lipid Metabolism
14h00-14h30
Mélanie PLOURDE, Research Center on Aging, Health and Social Services Centre, University
Institute of Geriatrics of Sherbrooke, Sherbrooke, Canada and Department of Medicine, University of
Sherbrooke, Sherbrooke, Canada.
Title: Ageing, cognitive decline, ApoE and DHA metabolism
14h30-15h00
Cristina LEGIDO-QUIGLEY. King's College London, Institute of Psychiatry, Psychology &Neuroscience, London, UK.
Title: Blood, CSF and brain metabolomics/lipidomics to study Alzheimer's Disease

Société Française pour l’Etude des Lipides
A non-governmental, non-profit scientific society founded in 1943
Organizing Committee: Dr Philippe Guesnet, Pr Elmira Arab-Tehrany, Dr Bernadette Delplanque,
Dr Claire Bourlieu, Dr Ali Tamayol, Dr Jean-Luc Olivier, Pr Michel Linder (President of SFEL)
Université de Lorraine – ENSAIA 2, avenue de la Forêt de Haye TSA 40602 54518 – VANDOEUVRE CEDEX
https://lipidsandbrain.event.univ-lorraine.fr/

15h00-15h30
Karl J.L FERNANDES, Faculty of Pharmacy, Université Laval, Quebec City, QC G1V 0A6, Canada;
CHU-Q Research Center, Quebec City, QC G1V 4G2, Canada.
Title: Abdormal brain lipid metabolism in Alzheimer
15h30 – 16h00

Coffee break / posters

16h00- 16h30
Marie-Claude POTIER. Centre National de la Recherche Scientifique UMR 7225, Institut National dela Santé et de la Recherche Médicale, U1127, Institut du Cerveau et de la Moelle, Sorbonne
Universités, UPMC Univ Paris VI UMR S 1127, Paris, France.
Title: Cholesterol and ApoE in Alzheimer's disease
16h30 - 17h00
Catherine MALAPLATE-ARMAND (UR AFPA INRA USC 340, EA 3998, Équipe Biodisponibilité etFonctionnalité des Lipides Alimentaires (BFLA), Université de Lorraine, Nancy, France. Laboratoire deBiochimie et Biologie Moléculaire, UF Oncologie Endocrinologie Neurobiologie, Hôpital Central,
Centre Hospitalier Universitaire, Nancy, France).
Title: Aged-related lipid raft modifications and higher susceptibility to amyloid stress
17h00 – 17h30
Jean-Luc OLIVIER. URAFPA, équipe Calbinotox et service de Biochimie-Biologie Moléculaire, CHU
de Nancy. France
Title: Potentialization of Aβ oligomer neurotoxicity by dietary arachidonic acid

Tuesday, 10 October 2017

Session 3: Impact of Omega 3 Fatty Acids and Lipid Nutrition
8h30-9h00
Nathalie BERNOUD-HUBAC. Université Lyon, INSA-Lyon, Inserm UMR 1060, Inra UMR 1397,
CarMeN Laboratory, IMBL, Villeurbanne F-69621, France.
Title: Structured phospholipids: an innovative therapeutic strategy for neurological diseases
9h30-10h00
Sophie LAYE. Université de Bordeaux. UFR Pharmacie. Laboratoire NutrINeuro Nutrition et
Neurobiologie Intégrée, 33076 Bordeaux, France.
Title: Polyunsaturated fatty acids and their metabolites in brain function and disease
10h00 – 10h30 Coffee break

10h30 - 11h15

Chevreul Medal: Stephen CUNNANE(Research Center on Aging, Sherbrooke Canada)

Is ketone production part of the role of omega-3 fatty acids in the brain?
11h15 -11h45
Richard P. BAZINET. Department of Nutritional Sciences, Faculty of Medicine, University of Toronto,
FitzGerald Building, 150 College St., Room 306, Toronto, ON, M5S 3E2, Canada.
Title: Brain omega-3 polyunsaturated fatty acids modulate microglia cell number andmorphology in response to intracerebroventricular amyloid-β 1-40 in mice
Société Française pour l’Etude des Lipides
A non-governmental, non-profit scientific society founded in 1943
Organizing Committee: Dr Philippe Guesnet, Pr Elmira Arab-Tehrany, Dr Bernadette Delplanque,
Dr Claire Bourlieu, Dr Ali Tamayol, Dr Jean-Luc Olivier, Pr Michel Linder (President of SFEL)
Université de Lorraine – ENSAIA 2, avenue de la Forêt de Haye TSA 40602 54518 – VANDOEUVRE CEDEX
https://lipidsandbrain.event.univ-lorraine.fr/

11h45-12h15
Jan PALMBLAD. Dept. of Medicine, Karolinska Institutet. Karolinska University Hospital Huddinge SE14186 Stockholm, Sweden. Title: Methylation of DNA in leukocytes from AD patients given
supplementation with omega-3 fatty acids
12h15 - 14h00

LUNCH (restaurant hippodrome)

Session 3: Impact of Omega 3 Fatty Acids and Lipid Nutrition
14h00-14h30
Joseph NICOLAZZO. Drug Delivery, Disposition and Dynamics, Monash Institute of Pharmaceutical
Sciences, Monash University, 381 Royal Parade, Parkville, Victoria 3052, Australia.
Title: Impact of Docosahexaenoic Acid on Alzheimer's Disease: and the Blood-Brain Barrier
14h30-15h00
Nicolas VITALE. INSERM Institut des Neurosciences Cellulaires et Intégratives. UPR-3212 CNRS Université de Strasbourg, France.
Title: Distinct role of mono and poly-unsaturated forms of phosphatidic acid in neurosecretionand neuronal growth
15h00-15h30
Gregory COLE. Professor UCLA Dept Medicine & Neurology, USA.
Title: Dietary DHA supplementation in an APP/PS1 transgenic rat model of AD reduces
behavioral and Aβ pathology and modulates Aβ oligomerization
15h30 – 16h00 Coffee break
16h00- 16h30
Nick van WIJK. Nutricia Advanced Medical Nutrition, Danone Nutricia Research, Utrecht, The
Netherlands.
Title: Targeting brain lipid metabolism in early Alzheimer's disease
16h30-17h00
Marcus GRIMM. Experimental Neurology, Saarland University, Kirrberger Str. 1, 66421
Homburg/Saar, Germany.
Title: The impact of Lipids and fat soluble Vitamins in Alzheimer´s disease
17h00-17h30
Cédric ANNWEILER. Department of Neuroscience, Geriatrics Division, Angers University
Hospital,Angers, France.
Title: Vitamin D and neurocognition in older adults

19h00-23h00 : Gala Dinner at the Former Hall of Nancy

Société Française pour l’Etude des Lipides
A non-governmental, non-profit scientific society founded in 1943
Organizing Committee: Dr Philippe Guesnet, Pr Elmira Arab-Tehrany, Dr Bernadette Delplanque,
Dr Claire Bourlieu, Dr Ali Tamayol, Dr Jean-Luc Olivier, Pr Michel Linder (President of SFEL)
Université de Lorraine – ENSAIA 2, avenue de la Forêt de Haye TSA 40602 54518 – VANDOEUVRE CEDEX
https://lipidsandbrain.event.univ-lorraine.fr/

Wednesday, 11 October 2017

Session 4: PUFA and Vectorisation in the Brain
8h30-9h00
Michel LAGARDE. CarMeN, Villeurbanne. France
Title: Acetyl,DHA-GPC: a structured phospholipid to provide DHA to the brain, with additional
acetylation effects
9h00-9h30
Gregory COLE. Professor UCLA Dept Medicine & Neurology.USA.
Title: Curcumin as an active drug delivered to brain for Alzheimer’s disease
9h30-10h00
Sophia G. ANTIMISIARIS. Dept. of Pharmacy, University of Patras, Greece.
Title: Nanoparticle based drug delivery systems crossing blood brain barrier
10h00 - 10h30 Coffee break
10h30-11h00
Elmira ARAB-TEHRANY. Université de Lorraine-Nancy, France.
Title: Active nanoliposome as the best DHA delivery
11h00-11h30
Sally A FRAUTSCHY. UCLA Dept Medicine & Neurology. USA.
Title: Roles for both Omega-3 and Omega-6 PUFA in Alzheimer Prevention
11h30-12h00
Emmanuel I. STRATAKIS. University of Crete Hellas Depart. of Materials Science and Technology
FORTH, Greece.
Title: PUFA and brain-on-a-chip microfluidic device
12h20 – 14h00 LUNCH (restaurant hippodrome)

14h00-14h30

Poster awards

14h30-15h00

Conclusion of the Congress by the Scientific Commitee of SFEL

Société Française pour l’Etude des Lipides
A non-governmental, non-profit scientific society founded in 1943
Organizing Committee: Dr Philippe Guesnet, Pr Elmira Arab-Tehrany, Dr Bernadette Delplanque,
Dr Claire Bourlieu, Dr Ali Tamayol, Dr Jean-Luc Olivier, Pr Michel Linder (President of SFEL)
Université de Lorraine – ENSAIA 2, avenue de la Forêt de Haye TSA 40602 54518 – VANDOEUVRE CEDEX
https://lipidsandbrain.event.univ-lorraine.fr/

Registration Fees LIPIDS and BRAIN IV: Lipids in Alzheimer disease

Lipids and Brain IV registration fees

Until 18/09/2017

After 18/09/2017

SFEL members- Updated membership 2017
- Futur SFEL members with membership 2017

490 €
570 €

590 €
650 €

Academic SFEL members- Updated membership 2017
- Futur SFEL members with membership 2017

290 €
370 €

390 €
470 €

100 €

200 €

Student (proof needed *)- With membership 2017
- Futur SFEL members with membership 2017

180 €
260 €

280 €
360 €

Gala dinner

95 €SFEL Retired Member

95 €According toavailability

Société Française pour l’Etude des Lipides
A non-governmental, non-profit scientific society founded in 1943
Organizing Committee: Dr Philippe Guesnet, Pr Elmira Arab-Tehrany, Dr Bernadette Delplanque,
Dr Claire Bourlieu, Dr Ali Tamayol, Dr Jean-Luc Olivier, Pr Michel Linder (President of SFEL)
Université de Lorraine – ENSAIA 2, avenue de la Forêt de Haye TSA 40602 54518 – VANDOEUVRE CEDEX
https://lipidsandbrain.event.univ-lorraine.fr/

Sponsoring Proposals

Super Gold Sponsor: Stand for posters /products presentation, display
on web and screens during the three days, documents in the bags.

Gold Sponsor: Invitation of « Médaille Chevreul »Silver Sponsor: display on web and screens during the three days,
documents in the bags

Silver Sponsor: poster at the restaurant's entrance and announcement
before lunch + sponsor indication on the menu. Display on web andscreens during the three days,
Bronze Sponsor: Bags with Logo. Display on web and screens during thethree days.

8 000 euros

6 000 euros

5 000 euros

4 000 euros

3 000 euros

Bronze Sponsor: availability of a booth for posters / productspresentation. Display on web and screens during the three days,

3 000 euros

Documents inside the bags: distribution to all the speakers and guests.
Display on web and screens during the three days.

2 500 euros

Sponsorship of a coffee break: poster + documents available. Display on
web and screens during the three days.

2 000 euros

Every sponsor’s logo will be on the “Journées Chevreul” leaflet.
Each funding of more than 3000 euros offers free access to conference and gala dinner to arepresentative of the sponsor and 2 for more than 6000 euros.
We are open to any other proposal.
For more informations, please contact:
bernadette.delplanque@u-psud.fr ; guesnet07@gmail.com ; elmira.arab-tehrany@univ-lorraine.fr ;michel.linder@univ-lorraine.fr

Société Française pour l’Etude des Lipides
A non-governmental, non-profit scientific society founded in 1943
Organizing Committee: Dr Philippe Guesnet, Pr Elmira Arab-Tehrany, Dr Bernadette Delplanque,
Dr Claire Bourlieu, Dr Ali Tamayol, Dr Jean-Luc Olivier, Pr Michel Linder (President of SFEL)
Université de Lorraine – ENSAIA 2, avenue de la Forêt de Haye TSA 40602 54518 – VANDOEUVRE CEDEX
https://lipidsandbrain.event.univ-lorraine.fr/

Medal CHEVREUL 2017: Pr Stephen CUNNANE
Société Française pour l’Etude des Lipides
A non-governmental, non-profit scientific society founded in 1943
Organizing Committee: Dr Philippe Guesnet, Pr Elmira Arab-Tehrany, Dr Bernadette Delplanque,
Dr Claire Bourlieu, Dr Ali Tamayol, Dr Jean-Luc Olivier, Pr Michel Linder (President of SFEL)
Université de Lorraine – ENSAIA 2, avenue de la Forêt de Haye TSA 40602 54518 – VANDOEUVRE CEDEX
https://lipidsandbrain.event.univ-lorraine.fr/

Previous congresses

Société Française pour l’Etude des Lipides
A non-governmental, non-profit scientific society founded in 1943
Organizing Committee: Dr Philippe Guesnet, Pr Elmira Arab-Tehrany, Dr Bernadette Delplanque,
Dr Claire Bourlieu, Dr Ali Tamayol, Dr Jean-Luc Olivier, Pr Michel Linder (President of SFEL)
Université de Lorraine – ENSAIA 2, avenue de la Forêt de Haye TSA 40602 54518 – VANDOEUVRE CEDEX
https://lipidsandbrain.event.univ-lorraine.fr/

NancyLA PLACE STANISLASA UNESCO World Heritage Site

ARTEM

REMOVING BARRIERS BETWEEN DICIPLINESTHE SCHOOL OF NANCY
AN ALLIANCE OF ART AND INDUSTRY

Société Française pour l’Etude des Lipides
A non-governmental, non-profit scientific society founded in 1943
Organizing Committee: Dr Philippe Guesnet, Pr Elmira Arab-Tehrany, Dr Bernadette Delplanque,
Dr Claire Bourlieu, Dr Ali Tamayol, Dr Jean-Luc Olivier, Pr Michel Linder (President of SFEL)
Université de Lorraine – ENSAIA 2, avenue de la Forêt de Haye TSA 40602 54518 – VANDOEUVRE CEDEX
https://lipidsandbrain.event.univ-lorraine.fr/

Gala Dinner on Tuesday 10
October 2017at the former hall of Nancy

Meals will be taken every lunchtime at
the restaurant “Hippodrome”(Monday,Tuesday and Wednesday)

Société Française pour l’Etude des Lipides
A non-governmental, non-profit scientific society founded in 1943
Organizing Committee: Dr Philippe Guesnet, Pr Elmira Arab-Tehrany, Dr Bernadette Delplanque,
Dr Claire Bourlieu, Dr Ali Tamayol, Dr Jean-Luc Olivier, Pr Michel Linder (President of SFEL)
Université de Lorraine – ENSAIA 2, avenue de la Forêt de Haye TSA 40602 54518 – VANDOEUVRE CEDEX
https://lipidsandbrain.event.univ-lorraine.fr/