No. DEFC0509

DEHYDRATED SOLVENT S

Date of issue : 2 Jun. 2020
Date of revision : 27 Jun. 2023
Safety Data Sheet

1.

Product and company identification
Product name

: DEHYDRATED SOLVENT S

Part No.

: E327339-A, E327339-B

Name of manufacturer

2.

: HIRANUMA Co., Ltd.

Address: 1739 Motoyoshida, Mito, Ibaraki, 310-0836, JAPANName of section: Quality assurance department

Telephone number: +81-29-247-7343

Facsimile number: +81-29-240-0381

Mail address: info-f2@hiranuma.com

Summary of danger and Hazard
GHS classificationPhysical and chemical hazard
Flammable liquids ：Category 2
Human health hazard
Acute toxicity (oral)：Category 4
Serious eye damage/eye irritation：Category 2A
Reproductive toxicity：Category 1BSpecific target organ toxicity (single exposure)：Category 1, Category 3 （anesthetic action）
Specific target organ toxicity (repeated exposure)：Category 1
Pictograms or symbols

Signal word

：DangerHazard statements：Highly flammable liquid and vapor
Harmful if swallowed－ 1/10 －No. DEFC0509

DEHYDRATED SOLVENT S

Causes serious eye irritationMay damage fertility or the unborn childCauses damage to organs (central nervous system, visualorgans, systemic toxicity)
May cause drowsiness and dizziness
Causes damage to organs (central nervous system, visualorgans) through prolonged or repeated exposure
Precautionary statements
Prevention：Do not handle until all safety precautions have been read andunderstood.
Keep away from ignition sources such as heat, sparks, or openflame.
Keep containers tightly closed.
Ground container and receiving equipment in case of transportand stirring.
Use explosion-proof apparatus.
Use only non-sparking tools.
Do not breathe dust, mist, and vapor.
Use only in a well-ventilated area.
Do not eat, drink or smoke when using this product.
Wear appropriate protective gloves, glasses, clothing, faceshield, or mask.
Wash hands thoroughly after handling.

Response：If inhaled : Remove victim to fresh air and keep at rest in aposition comfortable for breathing. Get medical treatment if you
feel unwell.
If swallowed: Rinse mouth, Get medical treatment if you feelunwell.
If in eyes : Rinse cautiously with water for several minutes.
Get medical treatment.
If on skin : Remove contaminated clothing and the substance.
Get medical treatment, if you feel unwell.
Wash hands thoroughly after handling.
If exposed, get medical treatment.
Get medical treatment, if you feel unwell.

Storage：Tightly container closed and store in a well-ventilated area.
Store locked up.

Disposal：Dispose of contents and containers appropriately in accordancewith related regulations.
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3.

DEHYDRATED SOLVENT S

Composition/Information on ingredients
Distinction of substance or mixture：SubstanceChemical nameConcentration (%)

Methanol4.

≥ 99.5

Formula
CH3OH

TSCA

EC-No.

CAS RN

Listed200-659-6

67-56-1

First aid measures
Inhalation：Remove the victim to fresh air, and make him blow his noseand gargle.

Skin contact：Wash the affected areas under running water.

Eye contact：Wash the affected areas under running water for at least 15
minutes. If necessary, get medical treatment.

Ingestion：Give the victim water or salt water and make him vomit. Do
not give an unconscious victim anything to drink. Get medicalattention.

Anticipated acute and delayed symptoms：Inhalation may cause cough, headache, dizziness, breath
shortness, and nausea, these symptoms may be late todevelop.
Protection for first aid person：Savers wear proper protective equipment like rubber gloves,
goggles.

5.

Fire fighting measures
Extinguishing media：Water, dry chemical powder, carbon dioxide, dry sand, alcohol
resistant foam

Prohibited extinguishing media：Foam extinguisher
Particular fire fighting：Move containers from fire area if it can be done without risk,
if not possible, apply water from a safe distance to cool andprotect surrounding area.
Dry chemical powder, carbon dioxide or dry sand should be
used for small fires. Alcohol-resistant foam extinguisher iseffective for a large scale fire.
Protection for firefighters－ 3/10 －No. DEFC0509

DEHYDRATED SOLVENT S：Wear breathing apparatus.

6.

Accidental release measures
Cautions for personnel：Wear proper equipment and avoid contact with skin andinhalation of vapor. Conduct operations from upwind andevacuate people downwind. Shut off all sources of ignition.
Keep away personnel except for authorized ones from spillagearea by stretching ropes.
Cautions for environment：Attention should be given not to cause damage to theenvironment by flowing of spillage to rivers. In case of thedilution of copious water, do not cause damage to theenvironment by untreated wastewater.
Methods and Equipment for Containment and Cleaning up
For containment：Absorb spill with inert material (e.g., diatomaceous earth, sand)and flush residual area with copious amounts of water.

Prevention of second accident：Remove nearby sources of ignition and prepare extinguishingmedia.

7.

Cautions of handling and storage
HandlingEngineering measures：Wear proper equipment not to contact with skin or inhale thevapor. Fire is strictly prohibited.
Ventilate well at working places.
Prevent build-up of electrostatic charges (e.g. by grounding).
Cautions for safety handling：Use with an enclosed system or a local exhaust ventilation.
Cautions：Do not contact with oxidizing substances.

Storage
Adequate storage condition：Store in a dark, cool place and tightly closed.
Safety adequate container materials：Glass, fluorine resin, stainless steel
Do not use vinyl chloride resin, acrylic resin, polystyrene etc.

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8.

DEHYDRATED SOLVENT S

Exposure control/Personal protection
Methanol

ACGIH TWA：200ppm
ACGIH STEL：250ppm

Engineering measures：Use with an enclosed system or a local exhaust ventilation.
Protective equipment
Respiration protective equipment：If necessary, wear chemical cartridge respirator with anorganic vapor cartage
Hands protective equipment：Impervious protective gloves
Eyes protective equipment：Safety goggles
Skin and body protective equipment：Protective clothing, protective boots9.

Physical and chemical properties
Appearance：LiquidColor：ColorlessOdor：Aromatic odor

pH：No data available

Melting point：-97.49 CFreezing point：No data available

Boiling point：64.51 C

Flash point：12 C

Auto-ignition temperature：470 C
Decomposition temperature：No data available
Flammability：Flammable

Vapor pressure：128hPa (20 C)

Relative density：No data available

Density：0.79g/cm3 (20 C)

Relative gas density ：1.1Solubility：Water：Freely soluble
Organic solvents：Miscible with many kinds of organic solvents
like ethanol, diethyl ether.
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DEHYDRATED SOLVENT SPartition coefficient n-octanol/water (log Pow)：-0.82
Explosive limits (vol %)：6.0 - 36.5 vol %Viscosity, kinematic：No data available

Particle characteristics：No data available

10. Stability and reactivity
Reactivity：React with oxidizing substances.

Chemical stability：Stable under normal conditions.

Possibility of hazardous reactions：React with oxidizing substances.
Conditions to avoid：Light, heat

Incompatible materials ：Oxidizing substances
Hazardous decomposition products：Carbon monoxide

11. Toxicological information
Acute toxicity (oral) ：Harmful if swallowed
rat LD50=7939mg/kg（as calculated value）
mouse LD50=7300mg/kg
human LD50=1400mg/kg
As the result of animal experiments, acute oral toxicity isclassified into out of category, however, the toxic effects ofmethanol in primates is more pronounced, therefore it wasclassified into category 4.
Acute toxicity (dermal)：No classification
rabit LD50=15800mg/kg
Acute toxicity (inhalation)：No classification (vapor)rat LC50>31500ppm/4H
Classification not possible (dust, mist)
Skin corrosion/irritation：Classification not possible
Methanol is described that it causes mild irritation to rabbit
skin by defatted effect after 24 hours exposure, but no－ 6/10 －No. DEFC0509

DEHYDRATED SOLVENT S

irritation to rabbit skin 20 hours obstruction tests, so it isimpossible to classify due to insufficient data.
Serious eye damage/eye irritation：Causes serious eye irritation
Methanol is recognized that it causes transient damage ofhuman cornea, and severe chemosis of conjunctive.
Respiratory sensitization：Classification not possible
Skin sensitization：No classification
Based on the description that Methanol has no skinsensitization by maximization test using guinea pig, it was set
into out of category.

Germ cell mutagenicity：Classification not possible
Methanol is negative in mouse erythrocyte micronucleus tests(in vivo somatic cell mutagenicity tests), by inhalation exposureand by intraperitoneal administration.
Carcinogenicity：Classification not possible

Reproductive toxicity ：May damage fertility or the unborn childIn a developmental toxicity test by inhalation exposure to mice
during organogenesis period, fetal resorptions and exencephaly
were observed. Additionally, similar effects including cleft palate
were reported in other inhalation and oral exposure tests.
For effects of methanol on reproduction, scientific decisions
concerning health risks are generally based on what is known
as weight-of-evidence approach. Recognizing the lack of humandata and the clear evidence of laboratory animal effects, it
was concluded that methanol may adversely affect humandevelopment if exposures are sufficiently high. Based on theinformation, the substance was considered to be a presumed
human reproductive toxicant and it was classified into category
1B.
Specific target organ toxicity (single exposure)：Cause damage to organs (central nervous system, visual organ,
systematic toxicity)
May cause drowsiness and dizziness
The symptoms of acute poisoning from methanol include CNSdepression. Formate accumulates in the blood during a latency
period which leads to metabolic acidosis, visual impairment or－ 7/10 －No. DEFC0509

DEHYDRATED SOLVENT S

even total blindness, headaches, dizziness, nausea, vomiting,Kussmaul breathing and coma. In some cases death is the finaloutcome. Further, CNS disorders, especially parkinsonism-likeextrapyramidal symptoms were reported. Morphological changes,
necrosis in the white substance of the brain weredemonstrated. Based on the human information, the substancewas classified into category 1 (central nervous system).
Additionally, the eye was regarded as a target organ sincevisual impairment is a characteristic effect. Additionally,systemic toxicity is regarded as a target organ based on thereports of headache, nausea, vomiting, tachypnea and coma as
signs of metabolic acidosis. The effects of single exposures byinhalation include narcosis. As an acute toxicity in humans, anarcotic effect results from central nervous system depression.
Based on the data, it was classified into category 3 (narcoticeffects).
Specific target organ toxicity (repeated exposure)：Cause damage to organs (central nervous system, visualorgans) through prolonged or repeated exposure
Based on a report that the most noted health consequence oflonger-term exposure to lower levels of methanol is a broad
range of ocular effects, and that cases of chronic poisoning
from occupational exposure to methanol were manifested bybilateral blindness, it was classified into category 1 (eye).
Additionally, based on the report that cases of chronicpoisoning from repeated exposure to methanol vapour aremanifested by headache, giddiness, insomnia, and gastricdisturbances, it was classified into category 1 (central nervoussystem).
Aspiration hazard：Classification not possible

12. Ecological information
Ecotoxicity
Aquatic acute：No classification
Crustacea (brine shrimp) LC50=1340mg/L/96H

Aquatic chronic：No classification

Persistence and degradability：Readily biodegradable BOD：92%－ 8/10 －No. DEFC0509

DEHYDRATED SOLVENT S

Bioaccumulative potential：Low bioconcentration log Pow：-0.82
Mobility in soil：High mobility Koc：2.75

Hazardous to the ozone layer：Classification not possible

13. Disposal consideration
Residual disposal：Burn in a chemical incinerator equipped with an afterburner anda scrubber. Or entrust approved waste disposal companies withthe disposal.

Containers：In case of disposal of empty bottles, dispose bottles after
removing the content thoroughly.

14. Transport information
International Regulations
Transport by sea(IMDG)UN No.(IMDG)：1230

Proper shipping name(IMDG)METHANOL
Packing group(IMDG)：ⅡTransport hazard class(es) (IMDG)：3 (6.1)
Air transport(IATA)
UN No.(IATA)：1230

Proper shipping name(IATA)：Methanol
Packing group(IATA)：Ⅱ
Transport hazard class(es) (IATA)：3 (6.1)
Marine pollutant ：Not applicable
Transport in bulk according to Annex II of MARPOL 73/78 and the IBC CodePollutant category：Y
MFAG-No：131

15. Regulatory information
Regulatory information with regard to this substance in your－ 9/10 －No. DEFC0509

DEHYDRATED SOLVENT S

country or region should be examined by your own
responsibility.

16. Other information
References
1) Company data on file2) NITE Chemical Risk Information Platform (NITE CHRIP), National Institute ofTechnology and Evaluation.
＊The information contained herein is based on several references and the present state of ourknowledge. However the SDS does not always cover all information about the product, handle theproduct carefully. The information is intended to ordinary usage, in case of particular handlings,
conduct appropriate safety measurements. The information herein is only provision of information,and it does not represent a guarantee the properties of the product. The Safety Data Sheet(SDS) is
prepared based on JIS Z7253.

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