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A newly devised text search system for adverse drug reactions.
Amano Hiro Kaneko Shuji
Department of Molecular Pharmacology, Graduate School of Pharmaceutical Sciences, Kyoto University.
In recent years, drug safety has become a major issue for those engaged in medical care. Although medical literatures areon a watch list for drug safty matter, it is a tremendous task to sort enormous amount of text information. We devised anexhaustive text search system for specialized use in pharmacovigilance termed TSADR (Text-search System for Adverse
Drug Reaction), which is made of two medical vocabularies (DN-INDI list and RN list) and a Perl script file. TSADR
extracts sentences involving topics relevant to the drug safety from PubMed abstracts, creates HTML files which show
extracted texts with drug names and adverse reaction names color-coded on pages in a web browser and assist searchers todiscriminate important items. TSADR is now developing toward the practical use for text analysis in pharmacovigilance toidentify and anticipate adverse reactions resulting from drug use.

Keywords: adverse drug reaction, literature information !"#$     !" # $ % & ' ( )* +   , -.
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