感染分子A欧文A−a
1. Furukawa H, Doh-ura K, Okuwaki R, Shirabe S, Yamamoto K, Udono H, Ito T, Katamine S, Niwa M: A pitfall in diagnosisof human prion diseases using detection of protease-resistant prion protein in urine: Contamination with bacterial outermembrane proteins. J Biol Chem 279 (22): 23661-23667, 2004 ＊2. Yamaguchi N, Sakaguchi S, Shigematsu K, Okimura N, Katamine S: Doppel-induced Purkinje cell death is stoichiometricallyabrogated by prion protein. Biochem Biophys Res Commun 3l9 (4): 1247-1252, 2004 ＊ ○★
3. Dougu S, Yamauchi A, Takata F, Sawada Y, Higuchi S, Naito M, Tsuruo T, Shirabe S, Niwa M, Katamine S, Kataoka Y:Uptake and efflux of quinacrine, a candidate for the treatment of prion diseases, at the blood-brain barrier. Cell Mol
Neurobiol 24 (2): 205-217, 2004 ＊4. Nishiura Y, Nakamura T, Fukushima N, Moriuchi R, Katamine S, Eguchi K: Increased mRNA expression of Th1-cytokine
signaling molecules in patients with HTLV-I-associated myelopathy/ tropical spastic paraparesis. Tohoku J Exp Med 204(4): 289-298, 2004 ＊5. Yoshizuka N, Moriuchi R, Mori T, Yamada K, Hasegawa S, Maeda T, Shimada T, Yamada Y, Kamihira S, Tomonaga M,Katamine S: An alternative transcript derived from the trio locus encodes a guanosine nucleotide exchange factor withmouse cell-transforming potential. J Biol Chem 279 (42): 43998-44004, 2004 ＊ ○▽6. Satoh K, Shirabe S, Eguchi K, Yamauchi A, Kataoka Y, Niwa M, Nishida N, Katamine S: Toxicity of quinacrine can be
reduced by co-administration of p-glycoprotein inhibitor in sporadic Creutzfeltdt-Jakob disease. Cell Mol Neurobiol 24 (6):873-875, 2004 ＊ ◎7. Atarashi R, Sakaguchi S, Shigematsu K, Katamine S: The absence of prion-like infectivity in mice expressing prion
protein-like protein. EXCLIJ 3: 82-90, 2004 ▽★
8. Ishikawa K, Doh-ura K, Kudo Y, Nishida N, Murakami-Kubo I, Ando Y, Sawada T, Iwaki T: Amyloid imaging probes areuseful for detection of prion plaques and treatment of transmissible spongiform encephalopathies. J Gen Virol 85 (6): 17851790, 2004 ＊ ☆
9. Arjona A, Simarro L, Islinger F, Nishida N, Manuelidis L: Two Creutzfeldt-Jakob disease agents reproduce prion proteinindependent identities in cell cultures. Proc Natl Acad Sci USA l0l (23): 8768-8773, 2004 ＊10. Sakudo A, Lee DC, Yoshimura E, Nagasaka S, Nitta K, Saeki K, Matsumoto Y, Lehmann S, Itohara S, Sakaguchi S,Onodera T: Prion protein suppresses perturbation of cellular copper homeostasis under oxidative conditions. Biochem
Biophys Res Commun 313 (4): 850-855, 2004 ＊ ☆
11. Nishimura T, Sakudo A, Nakamura I, Lee DC, Taniuchi Y, Saeki K, Matsumoto Y, Ogawa M, Sakaguchi S, Itohara S,Onodera T: Cellular prion protein regulates intracellular hudrogen peroxide level and prevents copper-induced apoptosis.
Biochem Biophys Res Commun 323 (1): 218-222, 2004 ＊ ☆

A−c
1. Sakaguchi S: Antagonistic roles of prion protein and prion protein-like protei in neurodegeneration. In Recent ResearchDevelopments in Experimental Medicine 1 (Pandalai SG ed; Transworld Research Network, Kerala) pp. 47-61, 2004

B 邦文B−c
1. 片峰 茂，新竜一郎：プリオン病. (モデル動物の作製と維持，エル・アイ・シー，pp. 659-663 所収) 2004
2. 片峰 茂：プリオン. (谷口直之，米田悦啓(編)：医学を学ぶための生物学，第2版，南江堂，pp. 300-305 所収)
2004
3. 片峰茂，山口尚宏：プリオン(クロイツフェルト・ヤコブ)病対策. (高崎真弓(編)：麻酔科診療プラクティス 15，
感染予防と安全対策，文光堂，pp. 58-61 所収) 2004−32−

長崎大学医学部業績集

2．研究業績

原著論文数一覧
2004

A−aA−bA−cA−d合計

SCI

B−aB−bB−cB−d合計

総計

1101012100030315

学会発表数一覧
A−bA−a2004

シンポジウム

学会

400

合計

B−a41B−bシンポジウム

学会

09

原著論文総数に係る教員生産係数一覧

2004

欧文論文総数

教員生産係数SCI掲載論文数

教員生産係数論文総数（欧文論文）

欧文論文総数（SCI掲載論文）

0.830.833

2.5

Impact factor 値一覧
2004

Impact factor

教員当たり Impact factor

論文当たり Impact factor

39.735

9.934

3.974

−33−合計総計

1014