2008年

TS-1 enhances the effect of radiotherapy by suppressing radiation-induced hypoxia-inducible factor-1
activation and inducing endothelial cell apoptosis.
Zeng L, Ou G, Itasaka S, Harada H, Xie X, Shibuya K, Kizaka-Kondoh S, Morinibu A, Shinomiya K,Hiraoka M.
Cancer Sci.
99(11) 2327-2335
2008

Biomedical applications of imidazolium cation-modified iron oxide nanoparticles.
Naka K, Narita A, Tanaka H, Chujo Y, Morita M, Inubushi T, Nishimura I, Hiruta J, Shibayama H, Kog
M.,Ishibashi S., Seki J., Kizaka-Kondoh S, M. Hiraoka.
Polym. Adv. Technol.
19 1421–1429 2008

Taip2 is a novel cell death-related gene expressed in the brain during development.
Yamada K., Akiyama N, Yamada S, Tanaka H, Saito S, Hiraoka M, Kizaka-Kondoh S.
Biochemical and Biophysical Research Communications
369(2) 426-31
2008

n-Propyl gallate activates hypoxia-inducible factor 1 by modulating intracellular oxygen-sensing
systems.
Kimura M, Takabuchi S, Tanaka T, Murata M, Nishi K, Oda S, Oda T, Kanai M, Fukuda K, Kizaka-KondohS, Adachi T, Takabayashi A, Semenza GL., Hirota K.
Biochemical J. 411(1) 97-105
2008

Near-Infrared Fluorescent Labeled Peptosome for Application to Cancer Imaging.
Tanisaka H, Kizaka-Kondoh S, Makino A, Tanaka S, Hiraoka M, Kimura S.
Bioconjug Chem. 19(1) 109-117 2008

Strain energy function of an Uncross-linked butadiene rubber estimated from planar extension
Kenji Urayama, Norio Akuzawa, Toshikazu Takigawa
Rheologica Acta 47(9) 1015-1021
2008

Aberrant catalytic cycle and impaired lipid transport into intracellular vesicles in ABCA3 mutants
associated with nonfatal pediatric interstitial lung diseaseYoshihiro Matsumura, Nobuhiro Ban, Nobuya Inagaki
Am J Physiol Lung Cell Mol Physiol 295(4) L698-707 2008

GLP-1 receptor signaling protects pancreatic beta cells in intraportal islet transplant by inhibiting
apoptosis
Kentaro Toyoda, Teru Okitsu, Shunsuke Yamane, Taeko Uonaga, Xibao Liu, Norio Harada, Shinji Uemoto,
Yutaka Seino, Nobuya Inagaki
Biochem Biophys Res Commun 367(4) 793-798 2008

Src activation generates reactive oxygen species and impairs metabolism-secretion coupling in diabetic
Goto-Kakizaki and ouabain-treated rat pancreatic islets
Rie Kominato, Shinpei Fujimoto, Eri Mukai, Yasuhiko Nakamura, Koichi Nabe, Makiko Shimodaira, Yuichi
Nishi, Shogo Funakoshi, Yutaka Seino, Nobuya Inagaki
Diabetologia 51(7) 1226-1235
2008

A novel GIP receptor splice variant influences GIP sensitivity of pancreatic beta-cells in obese mice
Norio Harada, Yuichiro Yamada, Katsushi Tsukiyama, Chizumi Yamada, Yasuhiko Nakamura, Eri Mukai,
Akihiro Hamasaki, Xibao Liu, Kentaro Toyoda, Yutaka Seino,Nobuya Inagaki
Am J Physiol Endocrinol Metab 294(1) E61-68 2008

The murine glucagon-like peptide-1 receptor is essential for control of bone resorption
Chizumi Yamada, Yuichiro Yamada, Katsushi Tsukiyama, Kotaro Yamada, Nobuyuki Udagawa, Naoyuki
Takahashi, Kiyoshi Tanaka, Daniel J Drucker, Yutaka Seino,
Nobuya Inagaki
Endocrinology 149(2) 574-579 2008

Lectin-like oxidized LDL receptor-1 (LOX-1) acts as a receptor for remnant-like lipoprotein particles(RLPs) and mediates RLP-induced migration of vascular smooth muscle cells
Yo Aramaki, Hirokazu Mitsuoka, Masako Toyohara, Toshikazu Jinnai, Kazushi Kanatani, Katsuyuki
Nakajima, Eri Mukai, Yuichiro Yamada,Toru Kita, Nobuya Inagaki, Noriaki Kume
Atherosclerosis 198(2) 272-9 2008

Intracellular ABC transporter A3 confers multidrug resistance in leukemia cells by lysosomal drug
sequestration
B Chapuy, R Koch, U Radunski, S Corsham, N Cheong, Nobuya Inagaki, Nobuhiro Ban, D Wenzel, DReinhardt, A Zapf, S Schweyer, F Kosari, W Klapper, L Truemper,
GG Wulf
Leukemia 22(8) 1576-1586
2008

Inhibition of GIP signaling modulates adiponectin levels under high-fat diet in mice
Rie Naitoh, Kazumasa Miyawaki, Norio Harada, Wataru Mizunoya, Kentaro Toyoda, Tohru Fushiki,
Yuichiro Yamada, Yutaka seino, Nobuya Inagaki
Biochem Biophys Res Commun 376(1) 21-25 2008
Analysis of factors influencing pancreatic β-cell function in Japanese patients with type 2 diabetes:association with body mass index andduration of diabetic exposure
Shogo Funakoshi, Shinpei Fujimoto, Akihiro Hamasaki, Yoshito Fujita, Yoshiyuki Hamamoto, Masaya
Hosokawa, Yutaka Seino, Nobuya Inagaki
Diabetes Res. Clin. Pract. 82 353-358 2008

Economic evaluation of 21-gene reverse transcriptase-polymerase chain reaction assay inlymph-node-negative, estrogen-receptor-positive, early-stage breast cancer in Japan.
Kondo M, Hoshi SL, Ishiguro H, Yoshibayashi H,Toi M.
Breast Cancer Res Treat 112 175-187 2008

Celecoxib anti-aromatase neoadjuvant (CAAN) trial for locally advanced breast cancer.
Chow LW, Yip AY, Loo WT, Toi M.
J Steroid Biochem Mol Biol 111(1-2) 13-17 2008

Evaluation of neoadjuvant inhibition of aromatase activity and signal transduction in breast cancer.
Chow LW, Yip AY, Loo WT, Toi M.
Cancer Lett 262(2) 232-238 2008

The aspartic protease napsin A suppresses tumor growth independent of its"Ueno T, Elmberger G, Weaver TE, Toi M, Linder S."
Lab Invest 88(3) 256-263 2008

catalytic activity.

Prolonged neutropenia after dose-dense chemotherapy with pegfilgrastim.
"Ishiguro H, KitanoT,Yoshibayashi H, Toi M, Ueno T,Yasuda H,Yanagihara K, Garbo C.L, Fukushima M."
Annals of Oncology 19(5) 1019-1020
2008Adipogenesis Induced by Human Adipose Tissue-Derived Stem Cells.
Wakako Tsuji, Takashi Inamoto, Hiroyasu Yamashiro, Takayuki Ueno, Hironori Kato, Yu Kimura, YasuhikoTabata, Masakazu Toi
Tissue Engineering: Part A 15(1) 83-93 2008

"Economic evaluation of chemoprevention of breast cancer with tamoxifen and raloxifene among highrisk women in Japan."
Kondo M ,Hoshi S, Toi M
British Journal of Cancer 100(2) 281-290 2008

The reversal of recurrence hazard rate between ER positive andnegative breast cancer patients withaxillary lymph node dissection(pathological stage I-III)3 years after surgery
Kiba T, Inamoto T, Nishimura T, Ueno M, Yanagihara K, Teramukai S, Kato H, Toi M, Fukushima M
BMC Cancer 8 323 2008
原発乳癌に対するFEC followed by docetaxel 100mg/m2併用療法による術前化学療法の検討-JBCRG02中村清吾、増田慎三、岩田広治、戸井雅和、黒井克昌、黒住昌史、津田均、秋山太
乳癌の臨床 23(2) 111(41)-117(47) 2008

A novel SCN5A gain-of-function mutation M1875T associated with familial atrial fibrillation.
Takeru Makiyama, Masaharu Akao, Satoshi Shizuta, Takahiro Doi, Kei Nishiyama, Yuko Oka, Seiko Ohno,Yukiko Nishio, Keiko Tsuji,Hideki Itoh, Takeshi Kimura, Toru Kita, Minoru Horie.
J Am Coll Cardiol.
52(16) 1326-34 2008

TRPM2-mediated Ca2+influx induces chemokine production in monocytes that aggravatesinflammatory neutrophil infiltration.
Shinichiro Yamamoto, Shunichi Shimizu, Shigeki Kiyonaka, Nobuaki Takahashi, Teruaki Wajima, Yuji Hara,Takaharu Negoro, Toshihito Hiroi,Yuji Kiuchi, Takaharu Okada, Shuji Kaneko, Ingo Lange, Andrea Fleig, Reinhold Penner, Miyuki Nishi,Hiroshi Takeshima, Yasuo MoriNat. Med. 14(7) 738-747 2008

Design and synthesis of biotinylated inositol phosphates relevant to the biotin-avidin techniques.
Kensaku Anraku, Teruhiko Inoue, Kenji Sugimoto, Takashi Morii, Yasuo Mori, Yoshinari Okamoto andMasami Otsuka
Org. Biomol. Chem. 6(10) 1822-1830 2008

Nitric oxide-cGMP-protein kinase G pathway negatively regulates vascular transient receptor potential
channel TRPC6.
Shinichi Takahashi, Hai Lin, Naomi Geshi, Yasuo Mori, Yasuhiro Kawarabayashi, Noboru Takami,Masayuki X. Mori, Akira Honda and Ryuji InoueJ. Physiol. 586(17) 4209-4223 2008

CACNB4 mutation shows that altered Ca(v)2.1 function may be a genetic modifier of severe myoclonic
epilepsy in infancy.
Iori Ohmori, Mamoru Ouchida, Takafumi Miki, Nobuyoshi Mimaki, Shigeki Kiyonaka, Teiichi Nishiki,
Kazuhito Tomizawa, Yasuo Mori and Hideki Matsui
Neurobiol. Dis. 32(3) 349-354 2008

Molecular characterization of TRPA1 channel activation by cysteine-reactive inflammatory mediators
Nobuaki Takahashi, Yusuke Mizuno, Daisuke Kozai, Shinichiro Yamamoto, Shigeki Kiyonaka, Takahiro
Shibata, Koji Uchida and Yasuo Mori
Channels 2(4) 287-298 2008

ボクセルデータ用高速多重極表面電荷法の誘導電界計算精度の評価
濱田昌司、北野允大、小林哲生
電気学会論文誌A 128(2) 223-234 2008

視覚情報の差異に伴う心的活動変化の自発脳波律動に基づく評価の試み
加藤和夫、志子田有光、望月菜穂子、石川敦雄、小林宏一郎、小林哲生
人間工学 44(2) 67-75 2008

手の運動およびそのイメージ時における脳波ベータ律動の変動
笹山瑛由、鄭 址旭、小林哲生
ヒューマンインタフェース学会論文誌 10(2) 85-94 2008

MR拡散テンソル画像における神経線維交叉部前後の方向ベクトル類似度探索による線維追跡法笈田武範、井前直人、鄭 址旭、小林哲生
電子情報通信学会論文誌D-II J91-D(7) 1886-1894 2008

低周波一様磁界中における偏心二導体球内の誘導電界二次・三次解析式
増谷圭吾、濱田昌司、小林哲生
電気学会論文誌A 128(12) 710-720 2008

Analysis of electric field induced by ELF magnetic field utilizing fast-multipole surface charge
simulation method for voxel data
Shoji Hamada and Tetsuo Kobayashi
Electrical Engineering in Japan 164(4) 1-10. 2008

Application of the equivalent multipole moment method with polar translations to forward calculationof neuromagnetic fields
Shoji Hamada, Mitsuhiro Kitano and Tetsuo Kobayashi
Electronics and Communication in Japan 91(4) 34-44 2008

Brain activation during exacution and imagery of simple wrist-bending movement:
Tomoaki Iida, Teruyoshi Sasayama, Takenori Oida, Masaki Ino and Tetsuo Kobayashi,
An fMRI study
1(1) 41-44 2008

Optimization of imaging parameters in MR-DTI for maximizing frectional anisotropy
Takenori Oida, Daiki Orio and Tetsuo Kobayashi
Proceedings of The 2nd International Symposium on Complex Medical Engineering 1(1) 87-902008

Descrimination between right and left hand movements and/or their imageries based on EEG fast
oscillatory activities
Teruyoshi Sasayama, Tomoaki Iida, Jiuk Jung and Tetsuo Kobayashi
Proceedings of The 2nd International Symposium on Complex Medical Engineering 1(1) 87-90 2008

An MR-DTI based fiber tracking method toword the multimodal study on cognitive brain functions
Proceedings of the 30th Annual International Conference of the IEEE
Tetsuo Kobayashi and Takenori Oida
Eingineering in Medicine and Biology Society 1(1) 5498-5501 2008

周波数標識された定常体性感覚誘発電位に基づくBMI
笹山瑛由、飯田智陽、鄭 址旭、小林哲生
電子情報通信学会技術研究報告 NC2008(5) 73-78 2008

手首の反復屈伸運動およびその運動イメージ時における脳活動：BMI実現にむけたfMRIによる基礎検討
飯田智陽、笹山瑛由、笈田武範、猪野正志、小林哲生
電子情報通信学会技術研究報告 NC2008(5) 49-54 2008

視覚誘導性サッカード課題遂行時における関連皮質活動の経時変化：fMRI-MEG統合解析法による検討
白澤佳大、鄭 址旭、笈田武範、小林哲生
電子情報通信学会技術研究報告 NC2008(5) 67-72 2008

脳梁を介した左右半球視覚野間におけるMR-DTI神経線維追跡手法の検討
坂上由英、笈田武範、小林哲生
電子情報通信学会技術研究報告 MI2008(6) 47-52 2008

脳磁界計測による奥行き注意下の運動透明刺激に誘発される脳活動の検討
夏川浩明、鄭 址旭、小林哲生
電子情報通信学会技術研究報告 MBE2008(10) 77-82 2008

The pH effect on the naphthoquinone-photosensitized oxidation of 5-methylcytosine
Hisatsugu Yamada, Kazuhito Tanabe, Takeo Ito, Sei-ichi Nishimoto
Chem. Eur. J. 14 10453–10461 2008

Radiolytic one-electron reduction characteristics of tyrosine derivative caged by 2-oxopropyl group
Kazuhito Tanabe, Masahiko Ebihara, Nao Hirata, Sei-ichi NishimotoBioorg. Med. Chem. Lett. 18 6126–6129 2008

One-Electron reductive template-directed ligation of oligodeoxynucleotides possessing disulfide bondKazuhito Tanabe, Emi Kuraseko, Yoshimi Yamamoto, Sei-ichi Nishimoto
J. Am. Chem. Soc. 130 6302–6303 2008

Radiolytic ligation of oligodeoxynucleotides possessing disulfide bondKazuhito Tanabe, Emi Kuraseko, Eiji Matsumoto, Hisatsugu Yamada, Take Ito, Sei-ichi Nishimoto
Nucleic Acids Symp. Ser. 52 459-460 2008

Structure of the SUMO-interacting motif of MBD1-containing chromatin associated factor 1 (MCAF1)
bound to SUMO-3.
Sekiyama, N., Ikegami, T., Yamane, T., Ikeguchi, M., Uchimura, Y., Baba, D., Ariyoshi, M., Tochio, H.,
Saitoh, H. and Shirakawa, M.
Journal of Biological Chemistry
283 35966-35975 2008

Hemi-methylated DNA recognition by the SRA protein Np95 via a base flipping mechanism.
Arita, K., Ariyoshi, M., Tochio, H., Nakamura, Y. and Shirakawa, M.
Nature455 818-821 2008
The solution structure of the C-terminal domain of NfeD reveals a novel membrane-anchored OB-fold.
Kuwahara, Y., Ohno, A., Morii, T., Yokoyama, H., Matsui, I., Tochio, H., Shirakawa, M., and Hiroaki, H.
Protein Science 17 1915-1924 2008

Expression, purification, and a structural analysis of human IL-18 binding protein: A potent
therapeutic molecule for allergy.
Kimura, T., Kato, Z., Ohnishi, H., Tochio, H., Shirakawa, M., Kondo,N.
Allergology International
4 367-376 2008

Intracellular protein delivery activity of peptides derived from insulin-like growth factor binding
proteins 3 and 5.
Goda, N., Tenno, T., Inomata, K., Shirakawa, M., Tanaka, T., Hiroaki, H.
Experimental Cell Research
314 2352-2361 2008

S1P1 receptor signaling overrides retention mediated by G alpha i-coupled receptors to promote T cellegress.
Trung H Pham, Takaharu Okada, Mehrdad Matloubian, Charles G Lo,
Jason G Cyster・Immunitｙ・28・1・122－133 2008

Fluorometric identification of 5-methylcytosine modification in DNA: Combination of photosensitizedoxidation and invasive cleavage
Yamada, H.; Tanabe, K.; Nishimoto, S.
Bioconjugate Chem. 19, 20-23 2008

Fundamental studies on electrokinetic chromatography with PEGylated phospholipid micelles,
Kitagawa, Fumihiko; Hasegawa, Takayuki; Taji, Hiromi; Onoue, Satomi; Tsuda, Yoshiko; Otsuka, Koji:
Anal. Sci. 2008, 24, 155-159 2008
Polymer microchip integrated with nano electrospray tip for electrophoresis−mass spectrometry
Shinohara, Hidetoshi; Suzuki, Takafumi; Kitagawa, Fumihiko; Mizuno, Jun; Otsuka, Koji; Shoji, Shuichi:
Sensors and Actuators B: Chemical 2008, in press 2008

On-line sample preconcentration and separation technique based on transient trapping in microchip
micellar electrokinetic chromatography
Sueyoshi, Kenji; Kitagawa, Fumihiko, Otsuka, Koji:
Anal. Chem. 2008, 80, 1255-1262 2008

Separation of nonionic compounds by electrokinetic chromatography using an inorganic layered
compound as a pseudostationary phase
Koike, Ryo; Kitagawa, Fumihiko; Otsuka, Koji:
J. Sep. Sci. 2008, 31, 829-836 2008

Micellar electrokinetic chromatography on microchips
Kitagawa, Fumihiko; Otsuka, Koji:
J. Sep. Sci. 2008, 31, 794-802 2008

"Nanosecond Dynamics of Poly(methyl methacrylate) Brushes in Solvents Studied by Fluorescence
Depolarization Method""Hiroyuki Aoki, Masafumi Kitamura, Shinzaburo Ito
Macromolecules, 41, 285-287" 2008"11. Conformation of Single Poly(methyl methacrylate) Chains in Ultra-Thin Film
Studied by Scanning Near-Field Optical Microscopy""Hiroyuki Aoki, Sayuri Morita, Ryojun Sekine, Shinzaburo Ito
Polym. J., 40, 274-280" 2008

Do anticholinergic agents suppress uterine peristalsis and sporadic myometrial contractions at cine MR
imaging?
Nakai, A. Togashi, K. Kosaka, K. Kido, A. Kataoka, M. Koyama, T. Fujii, S.
Radiology 246(2): 489-96. 2008

Plicae palmatae of the cervical canal visualized on MRI.
Takahata, A. Koyama, T. Yamada, K. Nishimura, T. Fujii, S. Togashi, K.
Br J Radiol 81(961): e4-6. 2008

Left ventricular functional analysis using 64-slice multidetector row computed tomography:
comparison with left ventriculography and cardiovascular magnetic resonance.
Wu, YW. Tadamura, E. Kanao, S. Yamamuro, M. Okayama, S. Ozasa, N. Toma, M. Kimura, T. Kita, T.
Marui, A. Komeda, M. Togashi, K.
Cardiology 109(2): 135-42. 2008