Nippi, Inc.
SAFETY DATA SHEET
Issue date: 23 Mar. 2022 (Ver. 3)
SECTION 1. Identification
Product name:Product code:
Synonyms:
Application:
Manufacturer:
Department:
Address:
Phone number:
E-mail:iMatrix-111
892 071, 892 072, 892 073, 892 075, 892 076
Recombinant human laminin-111 E8 fragment, laminin-111 E8
Culture substrate for cells adhering to laminin-111 E8
Nippi, Incorporated
Biological and Chemical Products Division
1-1-1 Senju Midori-cho, Adachi, Tokyo 120-8601, Japan+81-(3)-3888-5184
protein-info@nippi-inc.co.jp

SECTION 2. Hazard identification
GHS classification: Not a hazardous substance or mixture according to the Globally Harmonized System (GHS)
Other hazards:
Not available
SECTION 3. Composition/Information on ingredients
Recombinant human laminin-111 E8 fragment
Solvent: 20 mM phosphate buffer, 250 mM NaClSECTION 4. First aid measures
Inhalation:
Skin contact:
Eye contact:
Ingestion:

Remove from exposure area to fresh air immediately. Perform artificial respiration,
if necessary.
Immediately wash with water and/or warm water.
Immediately rinse with plenty of water.
Vomit immediately.

SECTION 5. Fire-fighting measures
Fire extinguisher:
Can use all kind of fire extinguisher.
Specific noxiousness:
No information available
Fire-fighting:
Use a water and/or fire extinguisher. Move container from fire area, if it can bedone without risk. Do not scatter spilled material with high-pressure water
streams. Keep upwind avoiding inhalation of hazardous vapors.
Protection of worker for fire-fighting: Recommend that worker wear protective equipment.
SECTION 6. Accidental release measures
Keep unnecessary people away. Recommend that worker wear protective equipment. Beware adhesion to skin andinhalation of materials. Gather spilled materials and dispose of waste according to Federal, State and Local
Regulations. Do not flush spilled material into sewer, because BOD and COD values of the waste-water increase. Washout small amount of spilled material by water and/or warm water.
SECTION 7. Handling and storage
Handling: Do not get wet strictly. Do not handle by bare hands. Use local exhaust ventilation, if necessary.
Recommend that worker wear protective equipment and improve the ventilation of a room.
Storage: Avoid high temperature/humidity. Store at 2 to 15°C. Avoid sunlight and ultraviolet light. Avoid contact withmoisture and/or proteolytic substance. Keep container tightly closed.

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SECTION 8. Exposure controls/personal protection
Permissible exposure limit: No data available
Equipment:
Recommend that provide local exhaust ventilation
Respiratory protection: Masks, respirator
Gloves:Appropriate protective gloves
Eye Protection:
Safety glasses
Clothing:
Appropriate protective (impervious) clothing
SECTION 9. Physical and chemical properties
Appearance:
Colorless liquid
Odor:
Odorless
Melting point/Freezing point: No data available
Boling point and range: No data available
Flammability:
No data available
Upper/lower flammability or explosive limits: No data available
Flash point:
No data available
Auto-ignition temperature: No data available
Decomposition temperature: No data available
pH:
7.0 - 7.6
Viscosity:
No data available
Solubility:
No data available
Partition coefficient: n-octanol/water: No data available
Vapor pressure:
No data available
Relative density:
No data available
Relative gas density:
No data available
Particle characteristics: No data available
SECTION 10. Stability and reactivity
Reactivity:
No hazardous reaction for most materials.
Chemical stability:
Stable under normal condition. But decomposed by proteolytic enzymes, acid andalkali.
Conditions to avoid:
Avoid contact with strong oxidizers, open flame, high temperatures, sparks andthe direct rays of the sun.
Incompatible materials: No data available
Possibility of hazardous reactions: No data available
Hazardous decomposition products: No data available
SECTION 11. Toxicological information
Acute toxicity:
No data available
Skin corrosion/irritation: No data available
Serious eye damage/eye irritation: No data available
Respiratory or Skin sensitization: No data available
Germ cell mutagenicity: No data available
Carcinogenicity:
No data available
Reproductive toxicity:
No data available
Specific target organ toxicity – single exposure: No data available
Specific target organ toxicity – repeated exposure: No data available
Aspiration hazard:
No data available

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Nippi, Inc.
SECTION 12. Ecological information
Ecotoxicity:
No information available
Persistence and degradability: No information available
Bioaccumulative potential:
No information available
Movability in soil:
No information available
Other adverse effects:
No information available
Hazardous to the ozone layer: No information available
SECTION 13. Disposal considerations
Use a large quantity of water to avoid increasing of BOD and COD values. Waste must be disposed of inaccordance with federal, state and local environmental control regulations.
SECTION 14. Transport information
UN Number:UN proper shipping name:Not available
ADR/RID: Not dangerous goods, IMDG: Not dangerous goods,
IATA: Not dangerous goods
Transport hazard class:Not applicable
Environmental hazards:
No information available
Special precautions for user:
Avoid contact with strong oxidizers, open flame, high temperatures,sparks and the direct rays of the sun.
Transport in bulk according to AnnexⅡof MARPOL 73/78 and the IBC Code: Not applicable

SECTION 15. Regulatory information
Japanese regulations
Fire Service Act:Not applicable
Poisonous and Deleterious:
Not applicable
Substances Control Law:
Not applicable
Industrial Safety and Health Act: Not applicable
Regulations for the carriage and storage of dangerous goods in ship: Not applicable
Civil Aeronautics Law:
Not applicable
Pollutant Release and Transfer Register Law: Not applicable
Export Trade Control Order:
Not applicable
SECTION 16. Other information
No other special information
Disclaimer
The above information is believed to be correct but does not purport to be all inclusive and shall be used only as aguide. The information in this document is based on the present state of our knowledge and is applicable to theproduct with regard to appropriate safety precautions. It does not represent any guarantee of the properties of theproduct. Nippi, Inc. and its Affiliates shall not be held liable for any damage resulting from handling or from contact
with the above product. See our website https://www.nippi-inc.co.jp/english/tabid/74/Default.aspx and/or thereverse side of invoice or packing slip for additional terms and conditions of sale.

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