Pilipinas Kao Inc.
GLOBAL PRODUCT STRATEGY SAFETY SUMMARYFARMIN DM2458
This document is a high-level summary intended to provide the general public with anoverview of product safety for this substance. It is not intended to replace the Safety Data
Sheet, which is available from suppliers and should be referred to for full details ofrecommended safety procedures for each type of use. It is not intended to replace orsupersede manufacturer’s instructions and warnings for their consumer products containing
this substance.

1. Substance Identity
Brand Name: FARMIN DM2458
Chemical Name: Amines, C12-16-alkyldimetyl
CAS Number: 68439-70-3

2. Uses and Applications

FARMIN DM2458 has a variety of different uses in the manufacture of surfactants,including amine oxides. Additionally the substance is used in the manufacture ofbenzalkonium salts to be used in biocide applications.
The substance is not sold to consumers and use is limited to Industrial use only.
Workers handling this substance should have the appropriate skills and training with
self-protect apparatus.

3. Physical/chemical properties
FARMIN DM2458 is a clear colourless liquid with a characteristic fatty amine odour and isinsoluble in water.
Property

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Global Product Strategy Safety Summary – FARMIN DM2458

Physical state

LiquidColour

Colourless clearOdour

Amine-like odour

pH

No information available

Density

0.7989 g/mL at 10 ºC

Melting point- 12.9 ºC

Boiling point

No information available

Flash point

137 °C (Cleveland open cup method)

Flammability (Optional)

No information available

Explosive properties

No information available

Self – ignition temperature

No information available

Vapour pressure

No information available

Water solubilityInsoluble

Octanol-water partition coefficient (log K ow )No information available

4. Health information

FARMIN DM2458 is an alkylamine which is classified as harmful if swallowed.
Information on other dimethylalkyl amines suggests that this substance will cause
severe burns when in contact with the skin and serious eye damage if in contact withthe eyes.
Consumer exposure is very unlikely as the substance is manufactured and handled
in industrial settings in closed systems (used as chemical intermediate). Consumers
will not come into contact with harmful levels of the substance as use in consumer
end-products is not foreseen.
Workers will not come into contact with this substance as it is manufactured andhandled in industrial settings in closed systems. Moreover, the vapour pressure of
the substance is low and therefore the exposure via inhalation will be limited. In caseof unintended exposure during maintenance, sampling, testing, or other procedures
workers should follow the recommended safety measures in the Safety Data Sheet(SDS).

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Global Product Strategy Safety Summary – FARMIN DM2458

Effect assessment

Result (REACH assessment)

Acute toxicity
Oral / inhalation / dermal

Harmful by the oral route. Not considered as
harmful by dermal or inhalation routes ofexposure.

Irritation / corrosion
Skin / eye / respiratory tract

Causes severe skin burns.
Causes skin irritation and eye irritation.

Toxicity after repeated exposure
Oral / inhalation / dermal

No information available.

Genotoxicity / Mutagenicity

Not mutagenic.

Carcinogenicity

No information available.

Toxicity for reproduction

No information available.

5. Environmental information
FARMIN DM2458 is very toxic to aquatic organism and considered very hazardous to theaquatic environment. The substance is readily biodegradable, will not persist in theenvironment and has a low potential of bioaccumulation. Adsorption potential of thesubstance is high and it is likely to bind to soil and suspended particles.
The amount of the substance released into the aquatic and terrestrial environment, however,is low indicating no risk for the aquatic and terrestrial environment. This is confirmed by anenvironmental exposure assessment showing that exposure can be minimised during all
steps of manufacture and industrial use.
Effect assessment

Result (REACH assessment)

Aquatic toxicity

Very toxic to aquatic organisms.
EC50 is <1 mg/L in fish, daphnia and algae.

Biodegradation

Readily biodegradable

Bioaccumulation potential

BCF values estimated to be below 2000.

PBT / vPvB

Not considered to be either PBT nor vPvB.

(Persistent, Bioaccumulative and Toxic /Very Persistent and Very Bioaccumulative)

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6. Exposure potential
Human health
FARMIN DM2458 is a raw material used in the production of amine oxide surfactants.
Additionally the substance is used in the manufacture of benzalkonium salts to be used inbiocide applications. Therefore exposure will only occur in an industrial setting to workers.
Consumers will not be exposed to this material. Exposure of workers in manufacturing
facilities is also considered very low because the process, storage and handling operations
are under strictly controlled conditions. The substance is rigorously contained in a closed
system by technical means during its whole life cycle. It is transported to another reactor orstorage tank using closed transfer pipes. Workers who might accidentally come in contact
with the non-formulated, undiluted substance should follow the safety measures
recommended in the Safety Data Sheet (SDS).

Environment
Manufacture of chemicals involving FARMIN DM2458 is a closed and automated processwith no aqueous effluent and no gaseous emissions released to the environment. During theindustrial use of the substance there is also a “No release” policy with all effluent being
stored in special containers dedicated to incineration.

7. Risk management recommendations
When using chemicals make sure that there is adequate ventilation. Always use appropriatechemical resistant gloves to protect your hands and skin and always wear eye protection.
FARMIN DM2458 is corrosive to the skin and causes serious eye damage so alkali-resistant
gloves and safety goggles or face shield should be worn. Appropriate clothing should beworn also. Do not eat, drink, or smoke where chemicals are handled, processed, or stored. If
this material gets on clothing take off immediately all contaminated clothing. If you have
inhaled this substance, move to fresh air and keep comfortable for breathing. If swallowed
this substance, seek medical attention if you feel unwell. Do not induce vomiting. If thissubstance gets into your eyes, rinse cautiously with water for several minutes. Remove
contact lenses, if present and easy to do. Continue rinsing. If this substance gets on yourskin, wash the skin with 2% acetic acid and plenty of water until slimy feeling disappears.
Seek medical attention immediately.

8. Regulatory information / Classification and labelling
Under GHS, substances are classified according to their physical, health, and environmental
hazards. The hazards are communicated via specific labels and the Safety Data Sheet. GHS
attempts to standardize hazard communication so that the intended audience (workers,consumers, transport workers and emergency responders) can better understand thehazards of the chemicals in use.

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Global Product Strategy Safety Summary – FARMIN DM2458

FARMIN DM2458 classification and labelling:
H302 Acute Toxicity (Oral)- Category 4

H314 Skin Corrosion / Irritation- Category 1B

H318 Serious Eye Damage / Eye Irritation- Category 1

H400 Aquatic Hazard (Acute)- Category 1

H410 Aquatic Hazard (Long-Term)- Category 1

Signal Word: Danger

Regulations relating to the manufacture, sale, transport, use and disposal will varydepending on country or region. Please consult the safety data sheet provided by thesupplier for full details.

9. Conclusion
FARMIN DM2458 is used under controlled conditions at industrial sites. The manufacturing
and use of FARMIN DM2458 does not pose a risk to humans or the environment if
instructions in the Safety Data Sheet are followed.

10. Contact information within company
For further information on this substance or product safety summaries in general, pleasecontact:
Name

Pilipinas Kao Inc.

Telephone number+63-8822-760-256

Fax number+63-8822-760-305

E-mail address

chemical@kao.co.jp

Additional information can be found at the International Council of Chemical Associations
portal, found at http://www.icca-chem.org/en/Home/ICCA-initiatives/global-product-strategy/.

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11. Glossary
Acute toxicity
Biodegradation
Bioaccumulation
Carcinogenicity
Chronic toxicity
GHS
HazardMutagenicity
Reprotoxicity
SensitisingHarmful effects after single exposure
Loss or transformation of a chemical by microorganisms
Accumulation of substances in the aquatic organisms
Effects causing cancer
Harmful effects after repeated exposures
Global Harmonized System
Danger or causing damage to human health or environment
Effect that changes genes
Combining teratogenicity, embryotoxicity and harmful effects onfertility
Allergenic

12. Date of issue
April 21 2014

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Global Product Strategy Safety Summary – FARMIN DM2458