! $ " # Original Articles!$)'#(%&*"#. Ando M, Kawazu M, Ueno T, Fukumura K, Yamato A, Soda M, Yamashita Y,
Choi YL, Yamasoba T, Mano H. Cancer-associated missense mutations of caspase-8 activate
nuclear factor-gB signaling. Cancer Sci 104 : 1002-8, 2013$. Chihara Y, Sato A, Ohtani M, Fujimoto C, Hayashi T, Nishijima H, Yagi M,
Iwasaki S. The effect of a first-generation H1-antihistamine on postural control : a preliminary
study in healthy volunteers. Exp Brain Res 231 : 257-266, 2013%. CordulaMatthiesa, Stefan Brill, Kaga K, Morita A, Kumakawa K, HenrykSkarzynski, Andre Claassen, YauHui, Charlotte Chiong, Joachim Müllerj, Robert
Behr. Auditory Brainstem Implantation improves Speech Recognition in Neurofibromatosis TypeII Patients. ORL 75 : 282-295, 2013&. Egami N, Kakigi A, Sakamoto T, Takeda T, Hyodo M, Yamasoba T. Morphologicaland functional changes in a new animal model of Ménière’s disease. Lab Invest 93 : 1001-1011,
2013'. Egami N, Ushio M, Yamasoba T, Yamaguchi T, Murofush T, Iwasaki S. The diagnostic value of vestibular evoked myogenic potentials in patients with Meniere’s disease. J Vestib
Res 23 : 249-257, 2013(. Fujimaki Y, Tsunoda K, Ishimoto SI, Okada K, Kinoshita M, Igaki H, Terahara
A, Asakage T, Yamasoba T. Non-invasive objective evaluation of radiotherapy-induced dry
mouth. Journal of Oral Pathology & Medicine 43(2) : 97-102, 2013). Fujimoto C, Egami N, Kinoshita M, Sugasawa K, Yamasoba T, Iwasaki S. Factors
affecting postural instability in Meniere’s disease. Otolaryngol Head Neck Surg 149 : 759-765,
2013*. Fujimoto C, Murofushi T, Chihara Y, Ushio M, Suzuki M, Yamaguchi T,
Yamasoba T, Iwasaki S. Effect of severity of vestibular dysfunction on postural instability in
idiopathic bilateral vestibulopathy. Acta Otolaryngol 133 : 454-461, 2013+. Fukumura K, Yamashita Y, Kawazu M, Sai E, Fujiwara S, Nakamura N,
Takeuchi K, Ando M, Miyazono K, Ueno T, Ozawa K, Mano H. STK10 missense mutations associated with anti-apoptotic function. Oncol Rep 30 : 1542-1548, 2013#". Inoue A, Iwasaki S, Ushio M, Chihara Y, Fujimoto C, Egami N, Yamasoba T. Effect of vestibular dysfunction on the development of gross motor function in children with profound hearing loss. Audiol Neurootol 18 : 143-151, 2013##. Inoue Y, Yabe T. Lomerizine therapy for the treatment of benign paroxysmal vertigo of childhood trnsitioning into atypical basilar migraine : A case report. Exp Therap Med 55 : 92-98,
2013#$. Iwasa Y, Nishio S, Yoshimura H, Kanda Y, Kumakawa K, Abe S, Naito Y, Nagai
K, Usami S. OTOF mutation screening in Japanese severe toprofound recessive hearing loss patients. BMC Medical Genetics 14 : 95, 2013
! 100 !

#%. Iwasaki S, Egami N, Inoue A, Kinoshita M, Fujimoto C, Murofushi T, Yamasoba
T. Ocular vestibular evoked myogenic potential elicited from binaural air-conducted stimulations :clinical feasibility in patients with peripheral vestibular dysfunction. Acta Otolaryngol 133 : 708713, 2013#&. Jin Y, Kondo K, Ushio M, Kaga K, Ryan AF, Yamasoba T. Developmental changes in
the responsiveness of rat spiral ganglion neurons to neurotrophic factors in dissociated culture :differential responses for survival, neuritogenesis and neuronal morphology. Cell Tissue Res 351 :
15-27, 2013#'. Kagoya R, Shinogami M, Kohno M, Yamasoba T. Distortion-product otoacoustic emission tests evaluate cochlear function and differentiate cochlear and vestibular schwannoma. Otolaryngol Head Neck Surg 148(2) : 267-71, 2013#(. Kakigi A, Takubo Y, Egami N, Kashio A, Ushio M, Sakamoto T, Yamashita S,
Yamasoba T. Evaluation of the Internal Structure of Normal and Pathological Guinea Pig
Cochleae Using Optical Coherence Tomography. Audiol Neurotol 18 : 335-343, 2013#). Kawazu M, Ueno T, Kontani K, Ogita Y, Ando M, Fukumura K, Yamato A, Soda
M, Takeuchi K, Miki Y, Yamaguchi H, Yasuda T, Naoe T, Yamashita Y, Katada
T, Choi YL, Mano H. Transforming mutations of RAC guanosine triphosphatases in humancancers. Proc Natl Acad Sci U S A 110 : 3029-3034, 2013#*. Kikuta S, Max L. Fletcher, Homma R, Yamasoba T, Nagayama S. Odorant Response Properties of Individual Neurons in an Olfactory Glomerular Module. Neuron 77 : 11221135, 2013#+. Kinoshita M, Iwasaki S, Fujimoto C, Inoue A, Egami N, Chihara Y, Ushio M,
Yamasoba T. Ocular vestibular evoked myogenic potentials in response to air-conducted soundand bone-conducted vibration in vestibular schwannoma. Otol Neurotol 34 : 1342-1348, 2013$". Kinoshita M, Sakamoto T, Kashio A, Simizu T, Yamasoba T. Age-related hearing
loss in Mn-SOD heterozygous knockout mice. Oxid Med Cell Longev. 2013 ; 325702$#. Kobayashi K, Nakao K, Kishishita S, Tamaruya N, Monobe H, Saito K, Kihara
A. Vascular malformations of the head and neck. Auris Nasus Larynx 40 : 89-92, 2013$$. Kondo K, Pak K, Chavez E, Mullen L, Euteneuer S, Ryan AF. Changes in responsiveness of rat spiral ganglion neurons to neurotrophins across age : differential regulation of survivaland neuritogenesis. Int J Neurosci 123 : 465-475, 2013$%. Kusumoto K, Akita H, Ishitsuka T, Matsumoto Y, Nomoto T, Furukawa R, ElSayed A, Hatakeyama H, Kajimoto K, Yamada Y, Kataoka K, Harashima H. Lipid
Envelope-Type Nanoparticle Incorporating a Multifunctional Peptide for Systemic siRNA Delivery
to the Pulmonary Endothelium. ACS Nano 7(9) : 7534-7541, 2013$&. Makizumi Y, Kashio A, Sakamoto T, Karino S, Kakigi A, Iwasaki S, Yamasoba
T. Cochlear implantation in a patient with osteogenesis imperfecta. Auris Nasus Larynx. 40(5) :510-513, 2013$'. Matsumoto Y, Nomoto T, Toh K, Cabral H, Murakami M, Christie RJ, Kim HJ,
Ogura T, Miyata K, Nishiyama N, Yamasoba T, Kataoka K. Intravital Real-Time
Confocal Laser Scanning Microscopy for the In Situ Evaluation of Nanocarriers. Cancer Targeted! 101 !

Drug Delivery 22 : 607-620, 2013$(. Miura Y, Takenaka T, Toh K, Wu S, Nishihara H, Kano MR, Ino Y, Nomoto T,
Matsumoto Y, Koyama H, Cabral H, Nishiyama N, Kataoka K. Cyclic RGD-linked
polymeric micelles for targeted delivery of platinum anticancer drugs to glioblastoma through theblood-brain tumor barrier. ACS Nano 7(10) : 8583-8592, 2013$). Naito T, Nishio S, Iwasa Y, Yano T, Kumakawa K, Abe S, Ishikawa K, Kojima H,
Namba A, Oshikawa C, Usami S. Comprehensive genetic screening of KCNQ4 in a large
autosomal dominant nonsyndromic hearing loss cohort : Geneotype-phenotype correlations and afounder mutation. PLoS One 8 : 5, 2013$*. Nakanishi W, Yamaguchi S, Matsuda A, Suzukawa M, Shibui A, Nambu A,
Kondo K, Suto H, Saito H, Matsumoto K, Yamasoba T, Nakae S. IL-33, but not IL25, is crucial for the development of house dust mite antigen-induced allergic rhinitis. PLoS One
8 : 10, 2013$+. Nakaya M, Kimura Y, Onuki Y, Kida W, Shiraishi A, Fujimoto C, Fuchigami T,
Watanabe K, Abe K. Endoscopic-assisted tonsillectomy. Laryngoscope 123 : 360-361, 2013%". Narushima M, Yamasoba T, Iida T, Sakamoto T, Kashio A, Karino S, Yamamoto
T, Kikuchi K, Mihara M, Koshima I. Supermicrosurgical Reconstruction for Congenital
Aural Atresia Using a Pure Skin Perforator Flap : Concept and Long-Term Results. Plastic andReconstructive Surgery 131 : 1359-1366, 2013%#. Nomura T, Monobe H, Tamaruya N, Kishishita S, Saito K, Miyamoto R, Nakao
K. Primary intraosseous squamous cell carcinoma of the jaw : two new cases and review of theliterature. Eur Arch Otorhinolaryngol. 270 : 375-9, 2013%$. Ohki M. Hyperectasis of the Tympanic Membrane. N Engl J Med 369 : 1046, 2013%%. Ohki M, Kikuchi S. Bilateral objective tinnitus in an infant with tuberous sclerosis. Int J Pediatr Otorhinolaryngol 77 : 290-293, 2013%&. Ohki M, Tayama N. Dysphagia due to isoniazid therapy for tuberculosis in a patient with
Lewy body dementia. Auris Nasus Larynx. 40 : 327-329, 2013%'. Kagoya R, Shinogami M, Kohno M, Yamasoba T. Distortion-Product Otoacoustic Emission Tests Evaluate Cochlear Function and Differentiate Cochlear and Vestibular Schwannoma .
Otolaryngol Head Neck Surg 148 : 267-271, 2013%(. Saito Y, Yoshida M, Ushiku T, Omura G, Ebihara Y, Shimono T, Fukayama M,
Yamasoba T, Asakage T. Prognostic value of p16 expression and alcohol consumption in
Japanese patients with oropharyngeal squamous cell carcinoma. Cancer. 119(11) : 2005-2011,2013%). Saito Y, Mitani H, Oguri S, Shinbashi W, Yonekawa H, Kawabata K. Occult functioning vagal paraganglioma in the infrahyoid carotid sheath. Auris Nasus Larynx. 40(3) : 330333, 2013%*. Sugasawa K, Iwasaki S, Fujimoto C, Kinoshita M, Inoue A, Egami N, Ushio M,
Chihara Y, Yamasoba T. Diagnostic usefulness of multifrequency tympanometry for
Meniere’s disease. Audiol Neurotol 18 : 152-160, 2013%+. Sumitomo S, Fujio K, Okamura T, Morita K, Ishigaki K, Suzukawa K, Kanaya K,! 102 !

Kondo K, Yamasoba T, Furukawa A, Kitahara N, Shoda H, Shibuya M,
Okamoto A, Yamamoto K. Transcription factor early growth response 3 is associated with
the TGF-`1 expression and the regulatory activity of CD4-positive T cells in vivo. J Immunol
191 : 2351-2359, 2013&". Tockary TA, Osada K, Chen Q, Machitani K, Dirisala A, Uchida S, Nomoto T,
Toh K, Matsumoto Y, Itaka K, Nitta K, Nagayama K, Kataoka K. Tethered PEG
Crowdedness Determining Shape and Blood Circulation Profile of Polyplex Micelle Gene Carriers. Macromolecules 46(16) : 6585-6592, 2013&#. Tsunoda K, Sasaki T, Tsunoda A, Kobayashi R, Ueha R, Shoji S. Undiagnosed submucous cleft palate interfering with inhalation therapy and a solution. J Allergy Clin Immunol131(2) : 619-621, 2013&$. Tsutsumi T, Ikeda T, Fukuoka Y, Watanabe K, Kikuchi S. Optokinetic stimulation canbreak Listing’s law without induction of eye movement. Auris Nasus Larynx. 40 : 343-347, 2013&%. Urata S, Kikuchi S, Ohki M, Tanaka S. Thrombophlebitis of the Head and Neck Causedby Eosinophilic Otitis Media. Otol Neurotol 34 : 908-911, 2013&&. Urata S, Ohki M, Tsutsumi T, Kikuchi S. Organised haematoma of the maxillary sinus :pathophysiological differences suggesting a new aetiological hypothesis. J Laryngol Otol. 127 :
519-524, 2013&'. Urata S, Yoshida M, Ebihara Y, Asakage T. Surgical management of a giant cervical
ganglioneuroma. Auris Nasus Larynx 40 : 577-580, 2013&(. Vollrath A, Schallon A, Pietsch C, Schubert S, Nomoto T, Matsumoto Y,
Kataoka K, Schubert US. A toolbox of differently sized and labeled PMMA nanoparticles
for cellular uptake investigations. Soft Matter 9(1) : 99-108, 2013&). Watanabe K. Enfermedad de Forestier . Acta Otorrinolaringol Esp 64 : 447, 2013&*. Watanabe K, Toki N. Forunculo de la nariz. Acta Otorrinolaringol Esp 64 : 382, 2013&+. Yamasoba T, Lin FR, Someya S, Kashio A, Sakamoto T, Kondo K. Current concepts
in age-related hearing loss : epidemiology and mechanistic pathways. Hear Res 303 : 30-38,
2013'". Yamauchi A, Imagawa H, Yokonishi H, Nito T, Yamasoba T, Sakakibara K,Tayama N. Phase difference of vocally healthy subjects in high-speed digital imaging analyzed
with laryngotopography. J Voice 27 : 39-45, 2013

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T, Kuroda R, Masuda S, Hashimoto S, Misawa H, Shindo N, Yamasoba T
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Aoki I, Kano MR, Urano Y, Kataoka K
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Chisato Fujimoto
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2013.7.21-24

Honolulu, USA

Development of enzyme-loaded PICsomes for enzyme/prodrug therapy
Anraku Y, Kishimura A, Kamiya M, Tanaka S, Nomoto T, Toh K, Matsumoto Y, Kano MR,
Urano Y, Nishiyama N, Kataoka K
Enhanced Antitumor Activity of Proteasome Inhibitor MG132-loaded Polymeric Micelle Drug Carriers
Matsumoto Y, Miyamoto Y, Nagasaka K, Matsumoto Y, Cabral H, Nishida H, Christie RJ,
Kawana K, Fujii T, Nishiyama N, Kataoka K
DDS Evaluation Using Intravital Real-Time Laser Scanning Confocal Microscopy
Matsumoto Y, Nomoto T, Toh K, Nishiyama N, Yamasoba T, Kataoka K
Tethering PEG density on polyplex micelles and stealthiness in blood circulation
Osada K, Tockary T, Chen Q, Dirisala A, Machitani K, Nomoto T, Matsumoto Y, Kataoka K
Intravital Monitoring of Intact siRNA Using Fluorescence Resonance Energy Transfer
Toh K, Nomoto T, Matsumoto Y, Watanabe S, Fukushima S, Chaya H, Christie RJ, Miyata K,
Nishiyama N, Kataoka K
Enhanced blood circulation of siRNA complexed with PEG-block-poly(L-lysine)for cancer treatment
Watanabe S, Chaya H, Nomoto T, Fukushima S, Toh K, Takemoto H, Liu X, Matsumoto Y,
Uchida S, Nangaku M, Osada K, Nishiyama N, Miyata K, Kataoka K
15th International Conference on human-computer interaction2013.7.21-26

Las Vegas

Evaluation of an information delivery system for hearing impairments at a school for deaf.
Ito A, Yabe T, Tsunoda K, Ueda K, Ifukube T, Tauchi H, Hiramatsu Y
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2013.8.21-24

PragueAnalysis of vocal fold vibrations using high-speed digital imaging in patients with vocal fold paralysis
Yamauchi A, Imagawa H, Yokonishi H, Sakakibara K, Ueha R, Nito T, Tayama N, Yamasoba T
Vocal fold atrophy patients in a Japanese tertiary medical institute : demographics and treatment
Yamauchi A, Imagawa H, Yokonishi H, Sakakibara K, Ueha R, Nito T, Tayama N, Yamasoba T
15th International Congress of Immunology

2013.8.22-27

MilanoNatural killer cells in upper respiratory airway.
Okada K, Sato S, Sato A, Inoue Y, Yabe T, Kiyono H
16th Asian Research Symposium in Rhinology

2013.8.29-31 B2

Innate immune responses and neuroepithelial degeneration in the mouse olfactory mucosa induced
by intranasal Poly(I : C)
Kondo K, Kanaya K, Suzukawa K, Kikuta S, Sakamoto T, Yamasoba T
Local increase of IgE and class switch recombination to IgE in the nasal polyps in chronic rhinosinusitis
Baba S, Kondo K, Toma-Hirano M, Kanaya K, Suzukawa K, Ushio M, Suzukawa M, Ohta K,
Yamasoba T
IL-33, but not IL-25, is crucial for the development of house dust mite antigen-induced allergic
rhinitis in mice
Nakanishi W
50th Inner Ear Biology Workshop

2013.9.11

Madrid, Spain

Intravital Calcium Imaging of Cochlear Hair Cells Upon Sound Stimulation
Matsumoto Y, Karino S, Namiki S, Kataoka K, Yamasoba T@$#.:G<CJ-

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Amsterdam

Oral nutritional support can shorten the duration of parenteral hydration in end-of-life cancer patients : A randomized exploratory trial
Ishiki H, Iwase S, Gyoda Y, Kanai Y, Ariyoshi K, Miyaji T, Tahara Y, Kawaguchi T, Yamaguchi T
AAO-HNSF Meeting Confirmation : 2013 Annual Meeting & OTO EXPO
2013.9.29-10.2()'!(!

Salvage surgery for locally recurrent pharyngeal squamous cell carcinoma after definitive radiotherapy or chemoradiotherapy
Omura G, Kobayashi K, Saito Y, Ando M, Ebihara Y, Asakage T, Yamasoba T
p16 and HPV DNA status in head and neck squamous cell carcinoma of an unknown primary site
Kobayashi K, Saito Y, Omura G, Ando M, Sakamoto T, Yamasoba T, Asakage T
Audio-Visual Vowel perception of Cochlear Implant Users
Ogata E, Akamatsu Y, Yamasoba T
Viral disruption of olfactory progenitors is exacerbated in allergic mice
Ueha R, Kondo K, Ueha S, M. Sumanta, Yamasoba T, N.W.Lukacs, S.L.Kunkel
Evaluation of postoperative hearing outcome and recurrence for pars flaccid cholesteatoma
Hoshi Y, Kashio A, Karino S, Sakamoto T, Kakigi A, Iwasaki S, Yasui T, Ito K, Suzuki M,
Yamasoba T
A New Method for Identifying Cochlear Ossification in Cochlear Implant Candidates with Deafness
following Meningitis
Ichikawa K, Kashio A, Ouchi A, Karino S, Sakamoto T, Kakigi A, Yamasoba T
Development research of communication systems for the deaf people in a major disaster.
Yabe T, Ito a, Tsunoda K, Okada K
Preoperative Evaluation of Round Window Niche Visualization in Cochlear Implantation by Meansof Computed Tomography
Kashio A, Sakamoto T, Karino S, Kakigi A, Iwasaki S, Yamasoba T
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Antalya, Turkey

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2013.11.25-26 4.30/1

Development of enzyme-loaded nano-sized polyion complex vesicles(PICsomes)for enzyme/prodrug
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Urano Y, Nishiyama N, Kataoka K
Polymeric micelles incorporating(1,2-diaminocyclohexane)platinum(II)as a drug delivery system fortargeting hepatic metastasis
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India

Safety and operability of cochlear implant electrodes coated with biocompatible polymer
Kinoshita M, Yamasoba T, Kikkawa Y, Kakigi A, Kondo K
12th Taiwan-Japan Conference on Otolaryngology Head and Neck surgery
2013.12.5-8

Taipei

Negative HPV status and alcohol consumption are significant risk factors for second primary malignancies in Japanese patients with oropharyngeal carcinoma
Saito Y, Omura G, Kobayashi K, Ando M, Sakamoto T, Yamasoba T, Asakage T
Intravital Microscopy for DDS Evaluation and Development
Matsumoto Y, Nomoto T, Toh K, Cabral H, Christie RJ, Tockary TA, Osada K, Miura Y,
Nishiyama N, Yamasoba T, Kataoka K
Histological changes of the nasal mucosa in a rat model of Vidian neurectomy
Nishijima H, Kondo K, Yamasoba T
Cancer-associated missense mutations of caspase-8activate NF-gB signaling
Ando M, Kobayashi K, Omura G, Saito Y, Asakage T, Yamasoba T, Mano H
Intartympanic neuroma without any trauma.
Yanagi Y, Yabe T, Okada K, Nakamura Y
A case of vast fibrovascular polyp in the hypopharynx
Oka M, Ueha R, Nito T, Yamasoba T
Precursor T-cell lymphoblastic lymphoma arising from the thyroid gland in a child
Yoshihara S, Nakaya M, Ichikawa T, Yuza Y, Kaneko T
Intratympanic Dexamethasone Perfusion for intractable Ménière’s Disease
Mizushima Y, Iwasaki S, Egami N, Yamasoba T# 129 #

The 12th US-Japan Symposium on Drug Delivery Systems
2013.12.16-20

Lahaina, Maui, HI, USA

Fine-tuning of PEG-b-polycations to form polyion complexes featuring single siRNA molecule
Hayashi K, Chaya H, Watanabe S, Fukushima S, Takemoto H, Nomoto T, Toh K, Matsumoto Y,
Osada K, Nishiyama N, Miyata K, Kataoka K
Intravital Microscopy for DDS Evaluation and Development
Matsumoto Y, Nomoto T, Toh K, Cabral H, Christie RJ, Tockary TA, Osada K, Miura Y,
Nishiyama N, Yamasoba T, Kataoka K
Tethering PEG density on polyplex micelles and stealthiness in blood circulation
Osada K, Tockary TA, Chen Q, Dirisala A, Machitani K, Nomoto T, Matsumoto Y, Kataoka K
Photosensitizer Encapsulated Nano Polyion Complex Vesicles(Nano-PICsome)for Enhanced In Vivo
Photodynamic Therapy
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