December 18, 2020
SymBio Pharmaceuticals Limited
Fuminori Yoshida
Representative Director,President and Chief Executive Officer
Completion, Monthly Exercise Status and Large Volume Exercise of the 51st Stock Acquisition Rights(with Exercise Price Revision Clauses) Issued by way of Third Party Allotment
TOKYO, Japan, December 18, 2020—SymBio Pharmaceuticals Limited (JASDAQ: 4582) announces the monthly
exercise status and the large volume exercise of the 51st Stock Acquisition Rights, and that the exercise of all 51st stockacquisition rights issued and allotted to EVO FUND on March 16, 2020, are completed as of today.
I. The Large Volume Exercise
Name of the stock acquisition(1)

SymBio Pharmaceuticals Limited 51st Stock Acquisition Rightsrights
Number of issued shares from the(2)previous disclosure
Number of stock acquisition rights
being exercised from the previous(3)

disclosure and the ratio to the

1,100,000 Shares
1,100,000 Units（Ratio to the total number of stock acquisition rights issued 3,000,000
units ：36.67％）

entire issue
Number of unexercised stock(4)

acquisition rights as of the

1,100,000 Units

previous disclosure
Number of remaining(5)

unexcercised stock acquisition

0 Unitsrights as of today(6) Exercise status from the previous disclosure
Number of delivered shares
Exercise Date

New Shares (Shares)

Treasury Shares

Number of stock
Exercise Price (¥)

Transferred (Shares)

acquisition rights
being excercised(Units)

December 4 (Fri)

--

362

-

December 7 (Mon)

--362

-

December 8 (Tue)

-

-

362

-

December 9 (Wed)

-

-

362

-

December 10 (Thu)

--

362

-

December 11 (Fri)

--

357

-

December 14 (Mon)

--357

-

December 15 (Tue)

--357

-

December 16 (Wed)--357-

December 17 (Thu)

--357

-

December 18 (Fri)

1,100,000-

343

1,100,000※Number of issued shares at the end of the previous month：36,499,331 shares〔of which 28,618 shares are treasuryshares〕

1II. Monthly Exercise Status
Name of the stock acquisition(1)

SymBio Pharmaceuticals Limited 51st Stock Acquisition Rights

rightsNumber of issued shares from the(2)1,700,000 Shares

beginning of the month
Number of stock acquisition rights
being exercised from the(3)1,700,000 Units(Ratio to the total number of stock acquisition rights issued 3,000,000beginning of the month and theunits ：56.67%）

ratio to the entire issue
Number of unexercised stock(4)

acquisition rights as of the

1,700,000 Units

beginning of the month
Number of remaining(5)

unexcercised stock acquisition

0 Unitsrights as of today(6) Exercise status from the beginning of the month
Number of delivered shares
Exercise Date

New Shares (Shares)

Treasury Shares

Number of stock
Exercise Price (¥)

Transferred (Shares)

acquisition rights
being excercised(Units)

December 1 (Tue)

--353

-

December 2 (Wed)

--353

-

December 3 (Thu)

600,000-353

600,000

December 4 (Fri)

-

-

362

-

December 7 (Mon)

-

-

362

-

December 8 (Tue)

--

362

-

December 9 (Wed)

-

-

362

-

December 10 (Thu)

-

-

362

-

December 11 (Fri)

-

-

357

-

December 14 (Mon)

-

-

357

-

December 15 (Tue)

-

-

357

-

December 16 (Wed)

-

-

357

-

December 17 (Thu)

-

-

357

-

December 18 (Fri)

1,100,000-

343

1,100,000※Number of issued shares at the end of the previous month：36,499,331 shares〔of which 28,618 shares are treasuryshares〕(7) Status concerning restriction on exercise (Status concerning compliance with exercise restrictions under Article 434 of
the Listing Regulations)①

Total number of shares to be②

Number of listed shares at thedelivered upon the exercise oftime of the payment for the

all series of stock acquisition

issuance③

Exercise ratio on exercise
limit(①/②)

rights1,700,000 Shares

28,122,581 Shares2

6.04％