Structural Biology Resources
Authors

Title

JournalVolumePageYear

DOI

Instrument

Notes

David P Klebl, Molly S C Gravett, Dimitrios
Kontziampasis, David J Wright, Robin SBon, Diana C F Monteiro, Martin
Trebbin, Frank Sobott, Howard D
White, Michele C Darrow, Rebecca F
Thompson0, Stephen P Muench

Need for Speed: Examining Protein Behavior during
CryoEM Grid Preparation at Different Timescales

Structure28

1238-12482020

10.1016/j.str.2020.07.018

chameleon

cryo-EMAlex J Noble, Hui Wei, Venkata PDandey, Zhening Zhang, Yong Zi Tan, Clinton
S Potter, Bridget Carragher

Reducing effects of particle adsorption to the air–water interface in cryo-EM.

Nat Methods

15793-795

2018

10.1038/s41592-018-0139-3

chameleon

cryo-EM

Anjan Debnath , Claudia M Calvet , Gareth
Jennings , Wenxu Zhou, Alexander
Aksenov , Madeline R Luth, Ruben Abagyan, W
David Nes, James H McKerrow, Larissa M
PodustCYP51 is an essential drug target for the treatmentof primary amoebic meningoencephalitis (PAM).

PLoS Negl
Trop Dis

11e0006104

2017

10.1371/journal.pntd.0006104

dragonfly crystal

optimizationPatrick K O'Neil, Lynn G L
Richardson, Yamuna D Paila, Grzegorz
Piszczek, Srinivas Chakravarthy, Nicholas
Noinaj, Danny Schnell

The POTRA domains of Toc75 exhibit chaperone-likefunction to facilitate import into chloroplasts.

Proc Natl
Acad Sci USA

114

E4868-E4876

2017

10.1073/pnas.1621179114

dragonfly crystal

optimization

Pablo Alcón, Guillermo Montoya, Stefano Stella

Assembly of Francisella novicida Cpf1 endonucleasein complex with guide RNA and target DNA.

Acta Crysta F73409-415

2017

10.1107/s2053230x1700838x

dragonfly crystal;mosquito crystal

optimization;
sitting drop

Emmanuel Nji, Yurie Chatzikyriakidou, MichaelLandreh, David Drew

An engineered thermal-shift screen reveals specificlipid preferences of eukaryotic and prokaryotic
membrane proteins.

Nat Commun

94253

2018

10.1038/s41467-018-06702-3

mosquito LCP

LCPMaria Martinez Molledo, Esben M
Quistgaard, Ali Flayhan, Joanna
Pieprzyk, Christian Löw

Multispecific Substrate Recognition in a ProtonDependent Oligopeptide Transporter.

Structure

26467-476

2018

10.1016/j.str.2018.01.005

mosquito LCPLCPPrakash Rucktooa, Robert K Y Cheng, ElenaSegala, Tian Geng, James C Errey, Giles ABrown, Robert M Cooke, Fiona HMarshall, Andrew S DoréTowards high throughput GPCR crystallography: InMeso soaking of Adenosine AA Receptor crystals

Sci Rep841

2018

10.1038/s41598-017-18570-w

mosquito LCP

LCP1Structural biology resources
Authors

Title

JournalVolume

Page

Year

DOI

Instrument

Notes

Wataru Shihoya, Tomohiro Nishizawa, Keitaro
Yamashita, Asuka Inoue, Kunio
Hirata, Francois Marie Ngako Kadji, Akiko
Okuta, Kazutoshi Tani, Junken Aoki, YoshinoriFujiyoshi, Tomoko Doi, Osamu Nureki

X-ray structures of endothelin ETB receptor boundto clinical antagonist bosentan and its analog.

Nat StructMol Biol

24758-764

2017

10.1038/nsmb.3450

mosquito LCP

LCP

Wendy Gaisford, Gebhard Schertler, PatEdwards

mosquito® LCP: Making membrane protein
crystallization accessible to the research scientist

Nat Methods

8i-ii

2011

10.1038/nmeth.f.345

mosquito LCP

hanging
drop; sitting
drop

Christopher A Kors, Ellen Wallace, Douglas RDavies, Liang Li, Philip D Laible, Peter Nollert

Effects of impurities on membrane-protein
crystallization in different systems.

Acta Cryst D

651062-1073

2009

10.1107/s0907444909029163

mosquito LCP

LCPAndrew R Tyler, Ronnie Ragbirsingh, Charles J
McMonagle, Paul G Waddell, Sarah E
Heaps, Jonathan W Steed, Paul Thaw, Michael
J Hall, Michael R Probert

Encapsulated Nanodroplet Crystallization ofOrganic-Soluble Small Molecules

Chem

6

1755-1765

2020

10.1016/j.chempr.2020.04.009

mosquito crystal

smallmolecule

Mintu Chandra, Yanni K-Y Chin, Caroline
Mas, J Ryan Feathers, Blessy Paul, Sanchari
Datta, Kai-En Chen, Xinying Jia, ZheYang, Suzanne J Norwood, Biswaranjan
Mohanty, Andrea Bugarcic, Rohan D
Teasdale, W Mike Henne, Mehdi Mobli, BrettM Collins

Classification of the human phox homology (PX)
domains based on their phosphoinositide binding
specificities.

Nat Commun

1015282019

10.1038/s41467-019-09355-y

mosquito crystal

sitting drop

María-Natalia Lisa, Virginija CvirkaiteKrupovic, Evelyne Richet, Gwenaëlle AndréLeroux, Pedro M Alzari, Ahmed Haouz, Olivier
Danot

Double autoinhibition mechanism of signaltransduction ATPases with numerous domains(STAND) with a tetratricopeptide repeat sensor.

Nucleic Acids
Res473795-3810

2019

10.1093/nar/gkz112

mosquito crystal

sitting drop

M Ejby, A Guskov, M J Pichler, G C Zanten, ESchoof, W Saburi, D J Slotboom, M Abou
Hachem

Two binding proteins of the ABC transporter thatconfers growth of Bifidobacterium animalis subsp.
lactis ATCC27673 on β‐mannan possess distinct
manno‐oligosaccharide‐binding profiles.

Mol Microbiol

112114-130

2019

10.1111/mmi.14257

mosquito crystal

hangingdrop; sitting
dropDukas Jurėnas, Laurence Van Melderen, Abel
Garcia-Pino

Mechanism of regulation and neutralization of theAtaR-AtaT toxin-antitoxin system.

Nat ChemBiol15285-294

2019

10.1038/s41589-018-0216-z

mosquito crystal

Yonca Ural-Blimke, Ali Flayhan, JanStrauss, Vasileios Rantos, Kim Bartels, Rolf
Nielsen, Els Pardon, Jan Steyaert, JanKosinski, Esben M Quistgaard, Christian Löw

Structure of Prototypic Peptide Transporter DtpA
from E. coli in Complex with Valganciclovir Provides
Insights into Drug Binding of Human PepT1.

J Am ChemSoc1412404-2412

2019

10.1021/jacs.8b11343

mosquito crystal

sitting drop2

Structural biology resources
Authors

Title

JournalVolumePageYear

DOI

Instrument

Notes

Robert M Cleverley, Zoe J Rutter, Jeanine
Rismondo, Federico Corona, Ho-Ching Tiffany
Tsui, Fuad A Alatawi, Richard A Daniel, SvenHalbedel, Orietta Massidda, Malcolm E
Winkler, Richard J Lewis

The cell cycle regulator GpsB functions as cytosolic
adaptor for multiple cell wall enzymes.

Nat Commun

10261

2019

10.1038/s41467-018-08056-2

mosquito crystal

sitting drop

Jonathan J Ruprecht, Martin S King, ThomasZögg, Antoniya A Aleksandrova, ElsPardon, Paul G Crichton, JanSteyaert, Edmund R S Kunji

The Molecular Mechanism of Transport by theMitochondrial ADP/ATP Carrier.

Cell

176

435-4472019

10.1016/j.cell.2018.11.025

mosquito crystal

sitting drop

Hong-Hsiang Guan, Yin-Cheng Hsieh, Pei-JuLin, Yen-Chieh Huang, Masato Yoshimura, LiYing Chen, Shao-Kang Chen, Phimonphan
Chuankhayan, Chien-Chih Lin, Nai-ChiChen, Atsushi Nakagawa, Sunney IChan, Chun-Jung Chen

Structural insights into the electron/proton transfer
pathways in the quinol: fumarate reductase from
Desulfovibrio gigas.

Sci Rep

8149352018

10.1038/s41598-018-33193-5

mosquito crystal

hangingdrop

Ivan Laponogov, Xiao-Su Pan, Dennis AVeselkov, Galyna B Skamrova, Trishant R
Umrekar, L Mark Fisher, Mark R Sanderson

Trapping of the transport-segment DNA by theATPase domains of a type II topoisomerase.

Nat Commun

92579

2018

10.1038/s41467-018-05005-x

mosquito crystal

sitting drop

John W Patrick, Christopher D Boone, WenLiu, Gloria M Conover, Yang Liu, XiaoCong, Arthur Laganowsky

Allostery revealed within lipid binding events tomembrane proteins

Proc Natl
Acad Sci USA

1152976-2981

2018

10.1073/pnas.1719813115

mosquito crystal

hangingdrop

Jan Kutner, Ivan G Shabalin, Dorota
Matelska, Katarzyna B Handing, Olga
Gasiorowska, Piotr Sroka, Maria W
Gorna, Krzysztof Ginalski, Krzysztof
Wozniak, Wladek Minor

Structural, Biochemical, and Evolutionary
Characterizations of Glyoxylate/Hydroxypyruvate
Reductases Show Their Division into Two Distinct
Subfamilies.

Biochemistry57963-977

2018

10.1021/acs.biochem.7b01137

mosquito crystal

sitting dropBenjamin Rothé, Catherine N Leettola, Lucia
Leal-Esteban, Duilio Cascio, SimonFortier, Manuela Isenschmid, James UBowie, Daniel B Constam

Crystal Structure of Bicc1 SAM Polymer andMapping of Interactions between the CiliopathyAssociated Proteins Bicc1, ANKS3, and ANKS6.

Structure

26209-224

2018

10.1016/j.str.2017.12.002

mosquito crystal

hangingdrop

Vanessa Vega-García, Adelaida DíazVilchis, Juan Pablo SaucedoVázquez, Alejandro Solano-Peralta, Enrique
Rudiño-Piñera, Wilhelm Hansberg

Structure kinetics, molecular and redox properties ofa cytosolic and developmentally regulated fungal
catalase-peroxidase.

Arch Biochem
Biophys

64017-26

2018

10.1016/j.abb.2017.12.021

mosquito crystal

sitting drop

Mitra S Rana, Pramod Kumar, Chul-Jin
Lee, Raffaello Verardi, Kanagalaghatta R
Rajashankar, Anirban Banerjee

Fatty acyl recognition and transfer by an integral
membrane S-acyltransferase

Science359

eaao6326

2018

10.1126/science.aao6326

mosquito crystal

LCP3

Structural biology resources
Authors

Title

JournalVolumePageYear

DOI

Instrument

Notes

Aleksandra E Sikora, Igor H
Wierzbicki, Ryszard A Zielke, Rachael F
Ryner, Konstantin V Korotkov, Susan K
Buchanan, Nicholas Noinaj

Structural and functional insights into the role ofBamD and BamE within the β-barrel assembly
machinery in Neisseria gonorrhoeae.

J Biol Chem

293

1106-1119

2018

10.1074/jbc.ra117.000437

mosquito crystal

hangingdrop

Tengchuan Jin, Mo Huang, Jiansheng
Jiang, Patrick Smith, Tsan Sam Xiao

Crystal structure of human NLRP12 PYD domain andimplication in homotypic interaction.

PLoS One

13e0190547

2018

10.1371/journal.pone.0190547

mosquito crystal

hangingdropGunjan Gautam, Syed Arif Abdul
Rehman, Preeti Pandey, Samudrala Gourinath

Crystal structure of the PEG-bound SH3 domain ofmyosin IB from Entamoeba histolytica reveals its
mode of ligand recognition.

Acta Cryst D

73672-682

2017

10.1107/s2059798317009639

mosquito crystal

hangingdropAmal Baklouti, Adeline Goulet, Julie
Lichière, Bruno Canard, Rémi NCharrel, François Ferron, Bruno
Coutard, Nicolas Papageorgiou

Toscana virus nucleoprotein oligomer organization
observed in solution.

Acta Cryst D73650-659

2017

10.1107/s2059798317008774

mosquito crystal

hangingdrop

Laziana Ahmad, Elizabeth L Rylott, Neil C
Bruce, Robert Edwards, Gideon Grogan

Structural evidence for Arabidopsis glutathionetransferase AtGSTF2 functioning as a transporter ofsmall organic ligands.

FEBS OpenBio

7122-1322016

10.1002/2211-5463.12168

mosquito crystal

sitting drop

Michael Collazo, Soheila Vaezeslami, Sarah
Burl

Improving the Crystallization Process for OptimalDrug Development

AmericanLaboratory2014

americanlaboratory.com/914Application-Notes/158649Improving-the-CrystallizationProcess-for-Optimal-DrugDevelopment/

mosquito crystal;mosquito LCP

optimization;
sitting drop

Ryosuke Nakashima, Keisuke Sakurai, Seiji
Yamasaki, Katsuhiko Hayashi, Chikahiro
Nagata, Kazuki Hoshino, Yoshikuni
Onodera, Kunihiko Nishino, Akihito Yamaguchi

Structural basis for the inhibition of bacterial
multidrug exporters.

Nature500

102-1062013

10.1038/nature12300

mosquito crystal;mosquito LCP

Kaspar Hollenstein, James Kean, Andrea
Bortolato, Robert K Y Cheng, Andrew S
Doré, Ali Jazayeri, Robert M Cooke, Malcolm
Weir, Fiona H Marshall

Structure of class B GPCR corticotropin-releasing
factor receptor.

Nature499

438-4432013

10.1038/nature12357

mosquito crystal;mosquito LCP

Akiko Koide, John Wojcik, Ryan N
Gilbreth, Robert J Hoey, Shohei Koide

Teaching an Old Scaffold New Tricks: Monobodies
Constructed Using Alternative Surfaces of the FN3
Scaffold.

J Mol Biol

415

393-4052012

10.1016/j.jmb.2011.12.019

mosquito crystal;mosquito LCP

hanging
dropTinatin I Brelidze, Anne E Carlson, Banumathi
Sankaran, William N Zagotta

Structure of the carboxy-terminal region of a KCNHchannel.

Nature481

530-5312012

10.1038/nature10735

mosquito crystal;mosquito LCP

sitting drop4

Structural biology resources
Authors

Title

JournalVolumePageYear

DOI

Instrument

Notes

Aram Chang, Shanteri Singh, Kate E
Helmich, Randal D Goff, Craig A Bingman, JonS Thorson, George N Phillips Jr

Complete set of glycosyltransferase structures in thecalicheamicin biosynthetic pathway reveals theorigin of regiospecificity.

Proc Natl
Acad Sci USA

108

17649-54

2011

10.1073/pnas.1108484108

mosquito crystal;mosquito LCP

sitting drop

Ilka Müller, Marieke B A C Lamers, Alison JRitchie, Hyunsun Park, Celia
Dominguez, Ignacio Munoz-Sanjuan, MichelMaillard, Alex Kiselyov

A new apo-caspase-6 crystal form reveals the active
conformation of the apoenzyme.

J Mol Biol410

307-3152011

10.1016/j.jmb.2011.05.020

mosquito crystal;mosquito LCP

sitting drop

Yelena Koldobskaya, Erica M Duguid, David M
Shechner, Nikolai B Suslov, Jingdong
Ye, Sachdev S Sidhu, David P Bartel, Shohei
Koide, Anthony A Kossiakoff, Joseph A
Piccirilli

A portable RNA sequence whose recognition by asynthetic antibody facilitates structural
determination.

Nat StructMol Biol

18100-106

2011

10.1038/nsmb.1945

mosquito crystal;mosquito LCP

sitting drop

Akira Watanabe, Seungho Choe, Vincent
Chaptal, John M Rosenberg, Ernest M
Wright, Michael Grabe, Jeff Abramson

The mechanism of sodium and substrate releasefrom the binding pocket of vSGLT.

Nature468988-9912010

10.1038/nature09580

mosquito crystal;mosquito LCP

sitting drop

Chu Wai Liew, Huaiyu Sun, Tony
Hunter, Catherine L Day

RING domain dimerization is essential for RNF4function.

Biochem J43123-29

2010

10.1042/bj20100957

mosquito crystal;mosquito LCP

sitting drop

Luis G Cuello, Vishwanath Jogini, D MarienCortes, Albert C Pan, Dominique GGagnon, Olivier Dalmas, Julio F CorderoMorales, Sudha Chakrapani, BenoîtRoux, Eduardo Perozo

Structural basis for the coupling between activationand inactivation gates in K(+) channels.

Nature466272-275

2010

10.1038/nature09136

mosquito crystal;mosquito LCP

sitting drop

Luis G Cuello, Vishwanath Jogini, D MarienCortes, Eduardo Perozo

Structural mechanism of C-type inactivation in K(+)
channels.

Nature466203-208

2010

10.1038/nature09153

mosquito crystal;mosquito LCP

sitting drop

Bjorn Vergauwen, Jonathan Elegheert, Ann
Dansercoer, Bart Devreese, Savvas NSavvides

Glutathione import in Haemophilus influenzae Rd isprimed by the periplasmic heme-binding protein
HbpA.

Proc Natl
Acad Sci USA

10713270-13275

2010

10.1073/pnas.1005198107

mosquito crystal;mosquito LCP

sitting drop

Joby Jenkins

Protein Crystallography: Automating atemperamental science.

Lab Manager

2007

labmanager.com/laboratorytechnology/proteincrystallography-automating-atemperamental-science-21109mosquito crystal;mosquito LCP

sitting drop

Janet Newman, David Egan, Thomas S
Walter, Ran Meged, Ian Berry, Marouane Ben
Jelloul, Joel L Sussman, David I
Stuart, Anastassis Perrakis

Towards rationalization of crystallization screening
for small- to medium-sized academic laboratories:
the PACT/JCSG+ strategy.

Acta Cryst D2005

10.1107/s0907444905024984

mosquito crystal;mosquito LCP

hanging
drop; sittingdrop61

1426-1431

5