Research Incubation Program: Frequently Asked Questions(Note)The below answer is general. The details may be discussed based on the individual status of theapplication.

⚫

What is the purpose of this Program?

Its objectives are to create new opportunities for industry-academia collaboration by matching research ideas heldby researchers at universities, companies, research institutions, etc. who promote research activities in Australia
and South Korea with research issues held by pharmaceutical companies.

⚫

What are the characteristics of this Program?

In addition to the research funding from Takeda, the awardees will obtain mentoring support by Takeda’s
researchers and access to facilities and services at the Shonan Health Innovation Park for up to three years. Inaddition, the above mentoring support will also be provided to the finalists prior to the final selection.

⚫

Has the stage level of the research proposal that this Program will seek been determined?

Stages of research proposals to application are not particularly limited, but some research activities have been
conducted to date, and those for which plans and pathways to their social implementation are clear (or concretediscussions are possible) are assumed as main subjects. However, this is not a strict requirement, so we would
appreciate it if you could consider applying even if it is not the case above.

⚫

What is “Mentoring Support”?

Mentoring Support refers to comprehensive support mainly provided by Takeda’s researchers, including scientificadvice on refining research plans and implementation, support for preparation of presentations for final selection,and sharing of know-how and introduction of internal networks to implement the research plans..

⚫

Is the number of awardees decided?

The number of awardees has not been decided, and we will decide after reviewing the proposals submitted. Please
note in advance that the awardee may not be identified as a result of the review.

⚫

I have multiple ideas. Can all of these be submitted?

You can apply. In that case, please apply for each idea.

⚫

There are some unclear points in how to fill out the Application Form. Who should I ask?

Please contact the following contact points by e-mail.

Program Office⚫

incubation-program@shonan-ipark.com

In attaching slides, are the contents and amount specified?

To the extent that the information in the slides is NOT confidential, we ask that the slides contain the following
points. The approximate number of slides is 10 -20 pages.

➢➢

Information on issues to be resolved, unmet medical needs, etc.
Technical information behind the proposal: Advantages in comparison with existing technologies andcompetitive research, your own research results to date, status of patent applications, etc.

➢Target achievement items in the 3-year research period, and experimental plans, major milestones,schedules, and budget plan to achieve them➢⚫

Investigator information (including joint researchers at other institutions)

Are there any restrictions on how the research fund can be used? Can I use it to hire research assistants orpurchase equipment?

The use of the research expenses shall be limited to those deemed necessary for the implementation of theresearch plan agreed in advance with Takeda. If agreed with Takeda, there is no problem with using the researchexpenses to hire research assistants or outsource a part of the study to an external CRO. We would like toindividually discuss the necessity of equipment purchase and handling of such equipment after purchase.

⚫

If the applicant's university or research institution has a guidance of indirect costs, will those costs beapplied?

In light of the purpose of this Program, we hope that you will use the provided funds as research expenses asmuch as possible. The funds to be provided are up to 10 million yen (approx. AUD115k/ KRW106 mn) per year
as a model case, and we would like you to understand that this amount includes indirect expenses. If youruniversity or research institution has some guidance about indirect expenses, we would like you to prepare andsubmit a research plan taking into account such expenses.

⚫

Is it possible to receive research assets (e.g., tool compound, data, etc.) from Takeda?

Takeda will consider it as case-by-case basis after proposals are submitted . If it is determined that some researchassets can be provided, Takeda may propose individual conditions for handling of research results, etc. based oncontributions from Takeda.

⚫

What kind of support will Shonan iPark provide to awardees?

Research space (laboratory space and office desks) in the Shonan Health Innovation Park (“Shonan iPark”) inKanagawa, Japan will be leased, if necessary, for up to three years at no cost to the awardee. The laboratory isequipped with specifications for general synthetic and biology experiments, and various shared equipment can beused free of charge. The space provided as free of charge will be for one person for each research team (for either
one biology or chemistry researcher). If you wish to conduct an animal experiment, the rent will be free, but theactual cost for animal maintenance will be paid.
You can also use Shonan iPark's planned and operated services, e.g., science mentoring by researchers conductedwith tenant companies, regulatory consultations, intellectual property consultations, etc.

⚫

We would like to use special laboratory equipment and facilities. Is it possible to conduct such an experiment
at Shonan iPark?

We would like to hear your request individually. Please contact the following contact.
Email address: incubation-program@shonan-ipark.com⚫

Is use of Shonan iPark mandatory for application?

Residence in Shonan iPark is not a prerequisite. However, even if you do not move in, please kindly cooperatewith the following activity.
⚫

Join Shonan iPark regular membership (at no cost)⚫

Research presentations at science seminars, etc. (approximately once a year)⚫

What happens if the research activity does not progress as planned?

If there is a significant gap between the research plan and actual progress, Takeda may ask you to discuss changes
in the plan or termination of the collaboration during the term of the collaborative research agreement withTakeda.

⚫

Image of 3 years later (after completion of the research period)

Upon expiration of the research term of the collaborative research agreement, the collaboration under thisProgram will terminate. However, if any useful results are generated from this collaboration, Takeda may
separately make proposals for further collaborations.

⚫

How will research results be handled?

We assume that data and inventions, etc. subject to intellectual property rights which will be obtained as research
results will belong solely to the awardee, and that the awardee as well as Takeda can use the research results
generated during the term at free of charge (Takeda will use them non-exclusively).

If Takeda wishes to do soeven after the end of the term of the collaborative research agreement, Takeda will have a right for a negotiation
period during which Takeda and the awardees will first discuss an exclusive license regarding the research results.
In addition to the above, the details of handling of research results will be communicated to the awardee after the
final selection by presenting a draft agreement (collaborative research agreement) from Takeda. In doing so,please note that depending on the individual contents of the application, we may propose the handling of research
results partially different from the above.

⚫

Is it possible to disclose research results at academic conferences or in journals?

If you wish to publish research results obtained from this Program, please consult with Takeda in advance.

⚫

If joint researches are already being conducted with other companies etc. regarding the applications
submitted to this Program, can such applications be accepted?

We will discuss this matter on a case-by-case basis after receiving the details. If it can be judged that Takeda's
rights to the results generated in this Program (see the preceding paragraph) can be secured, it may be adopted.

⚫

We submitted the same proposal for other grant programs. What will happen if it is adopted there?

If the proposal is adopted in a program other than this Program, it will be excluded from the applications for thisProgram.

End of Document