High-Performance Microplates
Aurora microplate products are constructed of Cyclo-Olefin Polymer (COP) which has distinctive
physical and chemical properties that are superior to polystyrene and polypropylene. Unlike
conventional microplates COP creates a superior combination of optical clarity, thermalstability, biocompatibility, low auto-fluorescence, flatness and chemical resistance. Aurora
holds exclusive knowledge in the use of this plastic in high-density microplates for laboratory
research. Plates are available in 384, 1536 and 3456 well configurations.

Key Attributes of Aurora MicroplatesHigh Light Transmittance: All Aurora plates exhibit high transmittance of UV, visible, andnear-IR wavelengths of light. This transmittance window is superior to other plastics used in opticalquantitation, including polystyrene, and results in improved research results. The plates support anexpanded optical window down to 230nm. The plates are well-suited for absorbance measurements ofDNA, nucleic acid, and protein concentrations at 260nm and 280nm.

Low Auto-Fluorescence: COP has less than 1% the native auto-fluorescence of polystyrene

when excited at UV wavelengths of light. The result for life-science researchers is better assay signal-tonoise performance and ultimately more sensitive results.

Broad Chemical Resistance:

Especially to DMSO and alcohol, this enables dual-use for storageof chemical compounds as concentrates, and in HT-screening applications for drug discovery.

Biocompatibility/Chemically Inert:

No catalysts or reactive intermediates are used during
the polymerization process. This results in a very inert surface, and overall plate composition. There are
no heavy metals or oxidizers present which can react with compounds or biological materials when
leeched by DMSO or other solvents. All Aurora plates are manufactured in Clean-Room Conditions, withISO 13485 Certification.

Thermal Stability: The plates exhibit excellent mechanical memory from -80°C to +120°C. Thiswide range of stability is conducive to cold storage, and thermal-cycling.

Rigidity and Mechanical Stability: COP’s material hardness and a 2.2GPa rigidity resists
microplate surface curvature by mechanical handling or heat treatments up to 120°C.

Protein Binding: The COP surface of an untreated microplate is hydrophobic and behaveschemically like untreated pure polypropylene. Proteins are not absorbed onto the surface. For sensitive
enzyme assays, an untreated plate is preferred. Surface treated plates are available to enable highbinding of protein material.

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Quality Commitment through Design and Manufacturing
Microplate Flatness and Film Thickness:

The flat-bottom design of Aurora microplates
are optimized for high-performance imaging and mutli-mode detection. The flat bottom allows for more
efficient plate washing results. The clear film- bottom of each microplate is a sheet of un-pigmented
COP which is fused by heat to the interstitial material between the wells during the molding process.
This provides an extremely flat (within 120µm), high transmittance window for optical measurements ofeach well. The bottom thickness is 100 or 188 microns.

Automation Compatible:

Aurora Plates meet the rigorous demands of laboratory automation.
The plates are qualified for fit and function that ensures reliable handling in robotic operations. Special
automation features on the plates include alignment fiducials, flanges and cutouts for positioning andembossing during microplate stacking routines.

Evaporation Management:

Aurora pioneered the use of extra wells surrounding the imaged
wells for use in evaporation control. An extra set of wells are populated with buffer or solvent to createa barrier to sample loss in the wells of interest. This feature is available in all Aurora plates (384, 1536,3456).

Low Evaporation Lids: Lids are available with all microplates. Each lid fits snugly anddramatically reduces sample loss due to evaporation. A series of channels restricts airflow yet allows forgaseous exchange in the well array. This reduces the transfer of water vapor between the wells and theexternal environment, and results in lower evaporation of aqueous solutions or reduced water uptake forDMSO solutions.

Private-Label, OEM and other Partner-Driven Designs
Please contact Aurora Microplates, Inc. for specific application-driven design
opportunities. We are committed to high-quality, high-utility microplate design andproduction for the life-science marketplace.

Contact:Charles Powell

Aurora Microplates, LLC.
charles@auroramicroplates.com
877-472-5955 Office877-472-5956 FAX

www.auroramicroplates.com