Request For Proposals for Independent Medical Educa�on Grants
New Mechanisms and Emerging Treatment Op�ons in Metasta�c Breast Cancer
Date of Release: May 2, 2024
I. BackgroundPﬁzer Inc. and Arvinas are collabora�ng to provide grant support for con�nuing professional
educa�on in Metasta�c Breast Cancer (mBC).
This publicly posted Request for Proposals (RFP) provides details regarding a general area ofinterest, sets �melines for review and approval, and describes an internal company alliancereview process to make ﬁnal grant decisions. Organiza�ons are invited to submit an applica�onaddressing the knowledge gaps as outlined in the RFP.
For all independent medical educa�on grants, the grant requester (and ul�mately the grantee)
is responsible for the design, implementa�on, and conduct of the independent ini�a�ve
supported by the grant. Neither Pﬁzer nor Arvinas may be involved in any aspect of project
development, nor the conduct of the independent educa�on program.
II. General Area of Interest for this RFP
This compe��ve grant program seeks to support independent medical educa�on ac�vi�esfocused on the evolving treatment landscape for pa�ents with ER+/HER2- mBC.
Applicants are encouraged to iden�fy and address the educa�onal needs of healthcare
professionals related to novel treatments in the evolving clinical landscape of ER+/HER2- mBC.
Proposed educa�onal ac�vi�es should focus on increasing the understanding of emerging
mechanisms of ac�on (MOA) of novel agents – par�cularly in the post-CDK4/6 inhibitor(s)se�ng. Projects that will be considered for grant support will focus on one or more of thefollowing:••Increasing understanding of emerging and novel therapeu�c agents in the evolving
treatment landscape of ER+/HER2- mBC
Exploring the current unmet needs in ER+/HER2- mBC, including the relevance andapplicability of biomarker tes�ng•Increasing understanding of diﬀeren�ated MOA of emerging therapies including
proteolysis targe�ng chimera estrogen receptor (PROTAC ER) degraders from that ofother endocrine therapies (e.g., SERDs)

Examples of educa�onal formats that will be considered under this RFP include but are notlimited to:••••••

On-agenda educa�onal sessions during live conferences
Mul�-company supported, stand-alone symposia
Expert interviews recorded at live conferences, conference coverage reviews
Online ar�cles, newsleter ar�cles, training courses, webinars
Social media posted & linked content
Videos, podcasts, infographics, anima�ons

III. Target Audience and Geographic Scope
The intended learner audience should include medical oncologists and other healthcare
professionals involved in breast cancer pa�ent care.
The geographic scope of this RFP is global with the United States as the primary priority.
IV. Applicant Eligibility Criteria
The following types of organiza�ons may apply: medical, nursing, allied health, and/or
pharmacy professional schools; healthcare ins�tu�ons (both large and small); professionalorganiza�ons/medical socie�es; medical educa�on companies; and other en��es with a
mission related to healthcare professional educa�on and/or healthcare improvement.
Please note:•••••

Only organiza�ons are eligible to receive grants, not individuals or medical prac�cegroups.
If the project involves mul�ple departments within an ins�tu�on and/or between
diﬀerent ins�tu�ons/organiza�ons/associa�ons, all ins�tu�ons must have a relevant roleand the reques�ng organiza�on must have a key role in the project.
The project/program lead must be an employee or contractor of the reques�ngorganiza�on.
Reques�ng organiza�on must be legally able to receive award funding directly fromPﬁzer Inc.
For projects oﬀering con�nuing educa�on credit, the reques�ng organiza�on must beaccredited.

V. Expected Approximate Monetary Range of Grant Applica�ons
Individual projects reques�ng up to $175,000 will be considered although smaller, focused
projects with lower budgets are preferred. The es�mated total available budget related to this
RFP is $250,000 USD. Award amounts include direct costs, ins�tu�onal overhead costs, andindirect costs.
VI. Key Dates•••••

RFP release date: Thursday, 2 May 2024
Grant Applica�on due date: Thursday, 27 June 2024
Please note the deadline is 23:59 Eastern Time (e.g., New York, GMT -5).
An�cipated Grant Award No�ﬁca�on Date: Monday, 29 July 2024
Grants will be distributed following a fully executed agreement with Pﬁzer.
An�cipated approximate Project Start and End Dates: September 2024 – January 2026
(15-month maximum execu�on �meline, i.e., from contract execu�on to provision ofﬁnal outcomes)VII. How to Submit
Please go to www.cybergrants.com/pﬁzer/knowledge and sign in. First-�me users should click“Create your password”. [Note: there are individual portals for each grant applica�on type.
Please be sure to use the URL above.]
Click the “Start A New Knowledge Gap Applica�on" buton.
In the applica�on:••••For the ques�on “What type of request are you submi�ng?” select Response to a
Request for Proposal (RFP)For the ques�on “Are you replying to a Request for Proposal (RFP) as part of theCompe��ve Grant Program?” select Yes
Select the following Compe��ve Grant Program Name: 2024 ONC G Arvinas-Pﬁzer New
mechanisms and emerging treatment op�ons in mBC IME
Select the following Primary Area of Interest: Oncology – Breast - KG

Complete all required sec�ons of the online applica�on and upload your project proposal (seeAppendix) in the General RFP Submission ﬁeld.
If you encounter any technical diﬃcul�es with the website, please click the “TechnicalQues�ons” link at the botom of the page.
If you have ques�ons regarding this RFP, please direct them in wri�ng to the Pﬁzer Grant Oﬃcer,
Jacqueline Waldrop (Jacqueline.Waldrop@pﬁzer.com) and the Arvinas Grants Director Jennifer
Schreiber (Jennifer.Schreiber@arvinas.com), with the subject line “2024 ONC G New
mechanisms, April 2024.”

VIII. Grant Agreements
If your grant is approved, your ins�tu�on will be required to enter into a writen grant
agreement with Pﬁzer Inc. on behalf of the Pﬁzer-Arvinas Alliance. Grant funding is being
provided by both companies so both Pﬁzer Inc. and Arvinas must be acknowledged as part ofstandard disclosures of support of independent medical educa�on.

Appendix
General RFP Submission Requirements
Applica�ons will be accepted via the online portal listed in the How to Submit sec�on of theRFP. Project Proposals should be single-spaced using Calibri 12-point font and 1-inch margins.
Note there is a 15-page limit exclusive of references. When uploading your Project Proposalplease ensure it addresses the following sec�ons:
Goals and Objec�ves
Brieﬂy state the overall goal of the project. List the objec�ves you plan to meet with yourproject, in terms of learning and expected outcomes.
Needs Assessment for the Project
Include a descrip�on of your organiza�on’s needs assessment for this proposed project which
may include a quan�ta�ve baseline data summary, ini�al metrics, or a project star�ng point(please cite data on gap analyses or relevant pa�ent-level data that informs the statedobjec�ves) in your target area.
Target Audience
Describe the primary audience(s) targeted for this project. Indicate whom you believe will
directly beneﬁt from the project outcomes. Describe the overall popula�on size as well as thesize of your sample popula�on.
Project Design and Methods
Describe the planned project, the educa�onal approach, and the way the planned methods
address the established need.
Innova�on
Explain what measures you have taken to assure that this project is original and does not
duplicate other projects or materials already developed. Describe how this project builds uponexis�ng work, pilot projects, or ongoing projects developed either by your ins�tu�on or otherins�tu�ons.
Evalua�on and Outcomes
In terms of the metrics used for the needs assessment, describe how your organiza�on will
determine if the gap was addressed for the target group. Iden�fy the sources of data yourorganiza�on an�cipates using to make the determina�on. Describe how your organiza�on is
expected to collect and analyze the data. Explain the method used to control for other factors
outside this project (e.g., use of a control group or comparison with baseline data). Quan�fy theamount of change expected from this project in terms the target audience. Describe how yourorganiza�on will determine if the target audience was fully engaged in the project.
Dissemina�on Plan
Describe how the project may have extended beneﬁt beyond the grant. Will the teachingmaterials be made available to others to use? Will there be tools or resources that are madepublicly available beyond the ini�al project. Describe how the project outcomes might bebroadly disseminated.
An�cipated Project Timeline
Provide an an�cipated �meline for your project including project start/end dates.
Addi�onal Informa�on
If there is any addi�onal informa�on you feel reviewers should be aware of concerning theimportance of this project, please summarize here.
Organiza�on Detail
Describe the atributes of the ins�tu�ons / organiza�ons / associa�ons that will support andfacilitate the execu�on of the project and the leadership of the proposed project. Ar�culate thespeciﬁc role of each partner in the proposed project.
Budget Detail
Please include a budget narra�ve that describes in greater detail the line items speciﬁed in thebudget submited within the applica�on.
While es�ma�ng your budget please keep the following items in mind:••

Independent Medical Educa�on grants cannot be used to purchase therapeu�c assets(prescrip�on or non-prescrip�on).
Overhead rates of up to 28% of the total proposed project budget may be supported.
General organiza�onal running costs such as legal fees, insurance, hea�ng, and ligh�ng
etc. should be included in an Ins�tu�onal Overhead (if required). These costs are notspeciﬁc to a grant request and therefore, should not appear as line items in budgets.