Pfizer Independent Medical Education RFP

PARP-inhibitor Combination
Treatments in Prostate Cancer, aGlobal Perspective
Competitive Grant Program – Pfizer Internal Review ProcessOverview
This competitive grant offering seeks to enhance learning
relative to the evolving paradigm of the potential
treatment of mCRPC with future PARP-inhibitor
combinations. The goal is to support relevant healthcare
providers in making evidence-informed decisions in a
rapidly evolving treatment landscape.

Geographic Scope
Global (knowledge gap coverage in Europe remains apriority)

Project Types and Area of InterestProjects that will be considered for Pfizer support will
focus on:• Increasing the understanding of the mechanism ofaction, biological and clinical rationale for PARPinhibitor combinations as potential treatments forprostate cancer.
• PARP-inhibitor combinations with androgen receptor
targeted therapies.
• The evolving paradigm of the potential treatment ofmCRPC with future PARP-inhibitor combinations.
• Optimal therapy management for PARP-inhibitor
combinations in prostate cancer.
All educational formats are in-scope, including novel andinnovative learning formats.
Enduring content and components are important.
It is not our intent to support clinical research projects.
Projects evaluating the efficacy of therapeutic or
diagnostic agents will not be considered.

Key Milestones•

Application submission deadline: August 10, 2023•

Anticipated decision notification date: September 8, 2023•

Anticipated project start date: October 23, 2023

I. Eligibility
Geographic Scope:•Global (knowledge gap coverage in Europe remains a priority)

Applicant Eligibility Criteria
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Only organizations are eligible to receive grants, not individuals or medical practice groups.
The following may apply: medical, nursing, allied health, and/or pharmacy professional schools;
healthcare institutions (both large and small); professional associations and medical societies; medical
education companies; and other entities with a mission related to healthcare professional education
and/or healthcare improvement.
If the project involves multiple departments within an institution and/or between different institutions /organizations / associations. All institutions must have a relevant role and the requesting organizationmust have a key role in the project.
The applicant must be the project/program lead or an authorized designee of such individual (e.g.,project/program lead’s grant coordinator).
The project/program lead must be an employee or independent contractor of the requesting organization.
Requesting organization must be legally able to receive award funding directly from Pfizer Inc. We
strongly recommend that applicants confirm this with their organization or institution prior to submitting anapplication. Grants awarded to organizations that are subsequently found to be unable to accept funding
directly from Pfizer Inc. may be subject to rescission.
For projects offering continuing education credit, the requesting organization must be accredited.

II. Requirements
Date RFP Issued•

June 21, 2023

Clinical Area•

Oncology – Genitourinary – ProstateTarget Audience•

Oncologists and all other healthcare professionals involved in the treatment of prostate cancer

Expected Approximate Monetary Range of Grant Applications:••Individual projects requesting up to $200,000 will be considered. The estimated total available budget
related to this RFP is $500,000.
Award amounts include direct costs, institutional overhead costs (capped at 28% per Pfizer policy), andindirect costs.

Key Dates:•••••

RFP release date: 6/21/2023
Grant Application due date: 8/10/2023
Please note the deadline is 23:59 Eastern Standard Time (e.g., New York, GMT -5).
Anticipated Grant Award Notification Date: 9/8/2023
Grants will be distributed following a fully executed agreement.
Anticipated Project Start and End Dates: 10/23/2023 to 11/1/20242

How to Submit:
Note: Please read this section carefully since applications submitted not following these instructions will not
be accepted and will be cancelled• Please go to www.cybergrants.com/pfizer/knowledge and sign in. First-time users should click “Createyour password”. [Note: there are individual portals for each grant application type. Please be sure to use the URLabove.]

Click the “Start A New Knowledge Gap Application" button.
• In the application:• For the question “What type of request are you submitting?” select Response to a Request for
Proposal (RFP)• For the question “Are you replying to a Request for Proposal (RFP) as part of the Competitive Grant
Program?” select Yes• Select the following Competitive Grant Program Name:
2023 ONC G PARP-inhibitor Combination Treatments in Prostate Cancer IME• Select the following Primary Area of Interest: Oncology-Genitourinary• Requirements for submission:
Complete all required sections of the online application and upload your project proposal (see Appendix)
in the General RFP Submission field.
• If you encounter any technical difficulties with the website, please click the “Technical Questions” link atthe bottom of the page.
IMPORTANT: Be advised applications submitted after the due date will not be reviewed.
•Questions:•If you have questions regarding this RFP, please direct them in writing to the Grant Officer, Dewayne
Brumlow (dewayne.brumlow@pfizer.com) with the subject line “2023 ONC GLOBAL PARP-inhibitor
Combination Treatments in Prostate Cancer.”

Grant Agreements:••••

If your grant is approved, your institution will be required to enter into a written grant agreement withPfizer. Please click here to view the core terms of the agreement.
Under Pfizer's competitive grant program, modifications to grant agreements will not be reviewed unless agenuine conflict exists as between applicable law and the terms of the relevant grant agreement.
Applicant is encouraged to share the core terms with counsel for approval prior to submitting anapplication.
Except where prohibited by applicable law and, in any case, subject to review by Pfizer Legal, payment ofgrant funding may only be paid to the grantee organization.
This RFP is supported by Pfizer Inc. and, if approved, payment will be sent from the United States.

Review and Approval Process•Grant requests received in response to a general RFP are reviewed by Pfizer to make final grant
decisions.

Mechanism by which Applicants will be Notified:••

All applicants will be notified via email by the dates noted above.
Applicants may be asked for additional clarification during the review period.

3About Pfizer Global Medical Grants
Pfizer Global Medical Grants (GMG) supports the global healthcare community’s independent initiatives(e.g., research, quality improvement, or education) to improve patient outcomes in areas of unmet medical
need that are aligned with Pfizer’s medical and/or scientific strategies.
Pfizer’s GMG competitive grant program involves a publicly posted general Request for Proposal (RFP)
that provides detail regarding a general area of interest, sets timelines for review and approval, and uses
an internal Pfizer review process to make final grant decisions. Organizations are invited to submit anapplication addressing the knowledge gaps as outlined in the specific RFP.
For all independent medical education grants, the grant requester (and ultimately the grantee) isresponsible for the design, implementation, and conduct of the independent initiative supported by thegrant. Pfizer must not be involved in any aspect of project development, nor the conduct of the
independent education program.

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Appendix
General RFP Submission Requirements
Applications will be accepted via the online portal listed in the How to Submit section. Project
Proposals should be single-spaced using Calibri 12-point font and 1-inch margins. Note there is a
15-page limit exclusive of references. When uploading your Project Proposal please ensure it
addresses the following sections:
Goals and Objectives••

Briefly state the overall goal of the project.
List the objectives you plan to meet with your project, in terms of learning and expected outcomes.

Needs Assessment for the Project•

Include a description of your organization’s needs assessment for this proposed project which may
include a quantitative baseline data summary, initial metrics, or a project starting point (please cite dataon gap analyses or relevant patient-level data that informs the stated objectives) in your target area.

Target Audience•Describe the primary audience(s) targeted for this project. Indicate whom you believe will directly benefit
from the project outcomes. Describe the overall population size as well as the size of your samplepopulation.

Project Design and Methods•

Describe the planned project, the educational approach, and the way the planned methods address theestablished need.

Innovation•Explain what measures you have taken to assure that this project is original and does not duplicate otherprojects or materials already developed. Describe how this project builds upon existing work, pilot
projects, or ongoing projects developed either by your institution or other institutions.

Evaluation and Outcomes•

In terms of the metrics used for the needs assessment, describe how your organization will determine ifthe gap was addressed for the target group. Identify the sources of data your organization anticipatesusing to make the determination. Describe how your organization is expected to collect and analyze thedata. Explain the method used to control for other factors outside this project (e.g., use of a control groupor comparison with baseline data). Quantify the amount of change expected from this project in terms thetarget audience. Describe how your organization will determine if the target audience was fully engaged
in the project.

Dissemination Plan•Describe how the project may have extended benefit beyond the grant. Will the teaching materials be
made available to others to use? Will there be tools or resources that are made publicly available
beyond the initial project. Describe how the project outcomes might be broadly disseminated.

Anticipated Project Timeline•

Provide an anticipated timeline for your project including project start/end dates.

5Additional Information•

If there is any additional information you feel Pfizer should be aware of concerning the importance of thisproject, please summarize hereOrganization Detail•

Describe the attributes of the institutions / organizations / associations that will support and facilitate theexecution of the project and the leadership of the proposed project. Articulate the specific role of eachpartner in the proposed project.

Budget Detail••Please include a budget narrative that describes in greater detail the line items specified in the budget
submitted within the application
While estimating your budget please keep the following items in mind:• Independent Medical Education Grants awarded by GMG cannot be used to purchase therapeuticassets (prescription or non-prescription).
• Overhead rates of up to 28% of the total proposed project budget may be supported by Pfizer.
Please click here for details.

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