Admission in Autumn (October ) 2024

Graduate School of Medicine(Doctoral Program)Student Application Guideline

National University Corporation

Shiga University of Medical ScienceTable of Contents

Admission Policy, etc. ......................................................................................................................... 1
Student Application Guidelines
Admission Quota ......................................................................................................................................... 4
Eligibility for ApplicantsApplication Procedure ................................................................................................................................. 5
Selection Method, etc. ............................................................................................................................... 7
Result Announcement ................................................................................................................................. 9
Enrollment Registration .............................................................................................................................. 9
Screening of Eligibility for Application .................................................................................................... 10
Handling of Private Information ............................................................................................................... 11
Campus Map ............................................................................................................................................. 12

Overview of the Graduate School of Medicine,
Doctoral Program (Medical Science)
Purpose ...................................................................................................................................................... 13
Structure
List of Classes and Number of Credits ...................................................................................................... 15
Major Study Themes of Faculty
Study Guide
Special Exception of Education Methods ................................................................................................. 15
Grant of Academic Degree ........................................................................................................................ 16
Appendix 1: List of Classes and Number of Credits ................................................................................. 17
Appendix 2: Major Study Themes of Faculty ........................................................................................... 22

Admission Policy, etc.
The Admission Policies○ Students that we want
In accordance with the University’s philosophy, we welcome individuals who have the knowledge, ability,
and skills necessary to become excellent medical researchers and medical professionals, and who will
work diligently and enthusiastically to acquire advanced medical research capabilities, as described below.
1. Those who are motivated to contribute to the progress and development of medicine and healthcare through scientific exploration in the fields of medicine, health care, life sc ience, andmedicine-related interdisciplinary fields.
2. Those who have international perspectives and a passion to play an active role in the world.
3. Those who have respect for life and high ethical standards.
4. Those who are motivated to play an active role as a leader to overcome diseases in a wide rangeof fields in industry-academia-government.
○ Student Selection
・Advanced Medical Science Course, Advanced Medicine for Clinicians Course and Interdisciplinary
Medical Science and Innovation Course
1. The Graduate School conducts a General Medicine and Life Science exam that separately tests
students' fundamental understanding and thinking abilities in the following areas: medicine, healthcare and life science, and medicine-related interdisciplinary fields.
2. We also conduct a foreign language examination (English) to measure students' global sense andtheir ability to express themselves.
3. In addition to the two abovementioned examinations, candidate students must undergo aninterview that confirms their passion for research, cooperative abilities, and high ethical standards.
・NCD Epidemiology Leader’s Course
1.

We conduct an essay examination to test applicants' basic knowledge about reducing
the incidence of Non-Communicable Diseases (NCD).

2.

We conduct a foreign language examination (English) to measure students' global
sense and their ability to express themselves.

3.

In addition to the two abovementioned examinations, candidate students must
undergo an interview that confirms their passion for research, cooperative abilities,
high ethical standards, and language ability.

4. We evaluate candidates by their submissions to confirm their passion for reducing theincidence of NCD in the world, doing research, and developing their language abilities.

The Curriculum Policies
The
To allow students to acquire advanced knowledge, skills, and ability stated in the Degree Policies, thecurriculum is organized as follows.
1.

Course Organization

1Admission Policy, etc.
The Graduate School provides common subjects (or core area subjects) so that students canacquire the specialized knowledge and research skills necessary for medical research, as well as
sufficient knowledge and a robust understanding of ethics, including medical ethics, bioethics,
and research ethics. In elective subjects, the School allows student to acquire cutting -edgeknowledge and research skills through lectures, exercises, and practical trainings in eachspecialized area, and to develop the ability to carry out research independently.
2. Education Methods(1) By establishing four courses, the Graduate School provides students with an organicallysystematized education as well as research opportunities offered by our entire faculty. In
addition, multiple faculty members shall be responsible for each student.
(2) The Graduate School stipulates several common and elective subjects.
The contents of the common subjects are as follows:①The Advanced General Medicine and Technical Seminar cultivates the expertise and researchskills required to become a medical researcher.
②Introduction to Ethics in Medicine and Life Science familiarizes students with knowledge andstandards in the fields of medical ethics, bioethics, and research ethics.
③Introduction to Epidemiology and Medical Statistics fosters the knowledge of epidemiology
and statistics that is necessary to conduct medical research.
④A seminar on the Integration of Fundamental Knowledge and Clinical Research encourages
students to learn knowledge and methodological approaches beyond the scope of conventional
basic and clinical studies. Elective Subjects foster students’ ability to independently conduct
research by utilizing the most advanced knowledge in their areas of specialization, and theirresearch skills.
(3) Each course provides its own characteristic subjects as indicated below:① The Advanced Medical Science Course fosters students' ability to conduct independent
research by providing them with opportunities to participate in advanced and unique research
projects that involve fundamental research ethics and the most advanced research tec hniques.
②Advanced Medicine for Clinicians Course develops students' ability to play leading roles inmedical settings by educating them on medical-related ethical and legal issues with a focus on
clinical research. Additionally, the course supports students in their training to qualify as
specialized physicians by providing the medical techniques that are necessary to serve as
experts.
③The Interdisciplinary Medical Science and Innovation Course fosters students' ability to play
important roles in areas of the industry-academia collaboration by providing not only medical
but also interdisciplinary knowledge, including engineering and physics, as w ell as practicalresearch skills.
④The NCD Epidemiology Leader’s Course covers epidemiology, clinical epidemiology, andpublic health, and fosters leaders in areas of the industry-academia-government collaboration

2

Admission Policy, etc.
to play active roles in reducing the incidence of NCD. The course includes practical training
with internships conducted outside the university.
3. Assessment of Learning OutcomesStudents’ achievement of the learning objectives stated in the syllabus will be assessed objectively
through multifaceted evaluation including examinations, reports, etc. In the third year, the progressof students’ research will be evaluated in the Qualifying Examination (QE) based on their poster
presentation, and the research advisory plan will be checked. Dissertation defense will be public
for rigor and transparency, and examine candidates’ knowledge, ability, and developmental
potential.

The Diploma Policies
To produce medical professionals as stated in the Purpose of Education, the Graduate School of Medicine
awards a Doctor of Philosophy (Medicine) degree to those who have attended the school for the prescribedperiod of time, completed the course requirements, passed the examinations, and acquired the following
professional knowledge and skills.
1. Students must have the necessary expertise and research skills as medical researchers.
2. Students must possess the excellent knowledge and ethics in the fields of medical ethics, bioethics,
and research ethics.
3. Students must have the ability to conduct research independently and disseminate research results
to the world.
4. Students must have the ability to contribute to the society through research and promotion of
medical science.
5. In addition to the above, students shall acquire the following abilities and knowledge for each of
the Courses listed below:(1) For the Advanced Medical Science Course, highly advanced knowledge and the ability to exert
leadership in government, industry, and academic settings, including in international conte xts.
(2) For the Advanced Medicine for Clinicians Course, knowledge and medical skills required toserve as a specialist, and the ability to exert leadership in medical fields.
(3) For the Interdisciplinary Medical Science and Innovation Course, interdisciplinary knowledge
and research skills to integrate medical fields with other areas.
(4) For the NCD Epidemic Leader’s Course, capability in researching about epidemiology andclinical epidemiology and being leaders in the world of industry-academia-government whoplay an active role in reducing the incidence of NCD.

3

Student Application Guidelines-Advanced Medical Science Course-Advanced Medicine for Clinicians Course

Admission Quota(* Including the Oncology Specialist Training Course andForensic Generalist, Forensic Specialist Training Course)-Interdisciplinary Medical Science and Innovation
Course- NCD Epidemiology Leader’s Course

About 3 students in Medical Science(including working students)*1 For the details of “the Oncology Specialist Training Course” and “Forensic Generalist, Forensic Specialist
Training Course,” please refer to the attached application guidelines.
(Note) For applicants who are willing to enroll while maintaining their job, “Special Exception of Education Method” according to
Article 14 of Graduate Schools Establishment Standards shall apply, and we may provide education through appropriate
means, which may include conducting classes or research guidance in the evening or other defined hours and periods.

Eligibility for Applicants1.

Those who have graduated or are expected to graduate from a school of medicine or dentistry of auniversity, or a six-year program of pharmacy or veterinary medicine by September 2024.

2.

Those who have completed or are expected to complete 18 years of school education (must include
medicine, dentistry, pharmacy, or veterinary medicine in the curriculum) by September 2024.

3.

Those who have completed or are expected to complete 18 years of school education in a foreign country(must include medicine, dentistry, pharmacy, or veterinary medicine in the curriculum), by taking courses
in correspondence education while in Japan provided by a school in a foreign country by September 2024.

4.

Those who have completed a curriculum (an applicant must complete 18 years of school education in aforeign country (must include medicine, dentistry, pharmacy or veterinary medicine in the curriculum)) inan educational institution in Japan that is deemed to have courses offered by an overseas college according
to the educational system of that country and have also been designated by the Ministry of Education,
Culture, Sports, Science and Technology.

5.

Those who have academic ability equivalent or superior to those who have completed a master’s
program or have earned a master’s degree, and have also been designated by the Minister of Education,
Culture, Sports, Science and Technology according to Notification No. 39 dated April 8, 1955, from the
Ministry of Education and Notification No. 118 dated September 1, 1989, from the Ministry of Education,
including those who are recognized to have an academic ability equivalent or superior to those who have
graduated from a school of medicine, dentistry, or veterinary medicine.

6.

Those who stayed in a six-year college for four years or more without graduating from it (a curriculum
must include medicine, dentistry, pharmacy, or veterinary medicine) and are recognized by our school thatthey have earned a designated number of credits with excellent grades.

7.

Those who have completed 16 years of school education in a foreign country (a curriculum must include
medicine, dentistry, pharmacy, or veterinary medicine); those who have completed 16 years of school
education in a foreign country (must include medicine, dentistry, pharmacy, or veterinary medicine in the
curriculum), by taking courses in correspondence education provided by a school in a foreign country; or4those who have completed a curriculum (an applicant must complete 16 years of school education in aforeign country (must include medicine, dentistry, pharmacy, or veterinary medicine in the curriculum)) inan educational institution in Japan that is deemed to have courses offered by an overseas college according
to the educational system of that country and have also been designated by the Minister of Education,
Culture, Sports, Science and Technology, while being recognized by our school to have earned a designatednumber of credits with excellent grades.
8.

Those who are recognized to have academic ability equivalent or superior to those who have graduatedfrom a college (a curriculum must include medicine, dentistry, pharmacy, or veterinary medicine) throughindividual screening of requirements for admission and who will be 24 years old before or on September
30, 2024.

(Notes) 1.

Applicants for working students must apply to one of the above criteria, already workat the point of application, and obtain approval from their supervisor for enrollment
while maintaining their job.

2.

If you apply, following any of the above criteria 5-8, please refer to “Screening of
Eligibility for Application” on page 10.

Application Procedure

1.

Period of Application
Thursday, July 25 to Wednesday, July 31, 2024
(as indicated by the postmark on the envelope)2.

Address to Submit Application Documents and Inquiry
Admissions Division, Entrance Examination Section
Shiga University of Medical Science
Seta Tukinowa-cho, Otsu City, Shiga 520-2192, Japan
Tel: +81-77-548-2071 (direct)

5

3.

Application Documents (Please use the designated forms for the documents marked with an asterisk*.)1

Required Document
Application for Admission

Note*

Prepared and sealed by the President (Dean) of the school attended.
Not required for those who have graduated/will graduate from our
Academic Transcript2
university. If you have completed/will complete a master’s program,(Japanese or English)
please also submit an academic transcript prepared and sealed by the
President (Dean) of the graduate school attended.
Prepared by the President (Dean) of the school attended. Not
Certificate of Graduation or
required for those who have graduated/will graduate from ourCertificate of Expected
university. If you have completed/will complete a master’s program,
3
Graduation
please submit only a certificate of completion (or a certificate of(Japanese or English)
expected completion) prepared by the President of the graduate
school attended.
After paying the 30,000 yen entrance examination fee using the
Payment verification form
deposit request form (designated by the university and included at
4 (included at the end of thisthe end of this booklet) between Thursday, July 11 and Wednesday,
booklet)* July 31,2024, at a bank, attach the “Certificate of Payment”
with stamp of receipt in its designated spot.
Examination Admission Card/ Attach your photo (upper front body, no hats, taken within the past5
Photo Card
* three months, 4 cm high × 3 cm wide) on the designated column.
Envelope for sending an
On the front of the envelope, write your name/address
6
Examination Admission Card * and attach postage stamps equivalent to 344 yen.
Fill in the address where you would like to receive a letter of
7 Address Card*
acceptance. Please do not remove the sticker mount.
Submit only if you are currently enrolled in another graduate school(unless expected to graduate by September 2024) or work in a
Letter of Permission for8
government, medical institution, company, etc. (It is not required if
Examination from a Supervisor
you currently attend our university.) (Refer to the attached format
example)9 Personal Statement* Form A In English (Only for applicants to the NCD Course)
Certification of English
10
Form B In English (Only for applicants to the NCD Course)
Proficiency*
Form C Prepared and sealed by a supervisor of the school or
11 Recommendation letter*
institute attended(Only for applicants to the NCD Course)(Notes) 1.

Applicants for the NCD Epidemiology Leader’s Course should download Forms A-C from the following
webpage.
https://www.shiga-med.ac.jp/admission/graduate/requirements
Documents 1-8 are the same for all courses.
2. Any change in the description will not be accepted after submitting your application. Regardless of reasons,application documents will not be returned once they are submitted.
3. The documents submitted for eligibility screening also can be used for this application procedure. You do
not need to submit the same documents twice.
4. If false information is found in the application documents, admission may be canceled even after
enrollment.

6

4.

Application Methods(1) Send by Postal mailPrepare application documents and send them in a designated envelop enclosed with this guideline by“registered express mail.”(2) Submit at School
Bring application documents to “2. Address to Submit Application Documents and Inquiry” on page
5. They will be accepted between 9:00 am and 5:00 pm. (except Saturdays and Sundays)

5.

Consultation with our Faculty before the Submission of Application (Mandatory)
To determine a course you would like to apply for, please do not fail to consult with the faculty member
whom you wish to receive guidance (refer to pages 22-30) before the submission of your application (orbefore Screening of Eligibility for Application if you take it.)In that case, call our main phone number (077-548-2111) or contact the faculty member directly.

6.

Considerations(1) An Examination Admission Card will be sent to an applicant by Monday, August 26 . If you do notreceive it by Wednesday, August 28, promptly contact “2. Address to Submit Application Documents
and Inquiry” listed on page 5.
(2) If you have any special considerations for taking the entrance examination or attending our school,such as a handicap, please inform us of “2. Address to Submit Application Documents and Inquiry”
listed on page 5 prior to your application.
(3) Refund procedure for those who are eligible to receive an examination fee refund:If you correspond with one of the following conditions, your examination fee can be refunded. If not,the fee will not be refunded for whatever reason. If you apply for a refund, contact “2. Address to
Submit Application Documents and Inquiry” listed on page 5 by Wednesday, August 28, 2024.
① Those who do not submit an application after paying the examination fee (application documents
were neither submitted nor accepted)② Those who paid the examination fee twice by mistake

Selection Method, etc.
1.

Selection Method
Written examination, interview, and application documents will be evaluated. Working applicants are notspecially selected separately from other applicants. The same selection process will be used for working
applicants.

7

2.

Examination schedule
Course name, examination type and point allocation

Date

Hours

Englishcompetenceexam

120 points

Englishcompetence
exam

50 points-Written exam
on general
12:30 – 13:30
medicine andlife science

120 points-Essay50 points

10:00 – 11:30
Tuesday,
September 3-Advanced Medical Science
Course-Advanced Medicine for Clinicians -NCD Epidemiology Leader’s
CourseCourse-Interdisciplinary Medical Scienceand Innovation Course

Interview
Interview*1*2 *3(individual)(individual)*1. In the interviews for Advanced Medical Science Course, Advanced Medicine for Clinicians
Course, and Interdisciplinary Medical Science and Innovation Course, a scale is used to assess
the qualities and aptitude to become an medical educator and/or researcher, and the results aretaken into account in the overall evaluation.
*2. For NCD Epidemiology Leader’s Course applicants, an individual interview will be conducted
in English to determine if the applicants are suitable for our program in terms of qualifications
and academic ability.
*3. For NCD Epidemiology Leader’s Course applicants, the total points allotted for the interview andapplication documents (English essay, English proficiency, and recommendation letter) will be
140 points.
14:00 –

(Note) 1. Only graphite pencils (including mechanical pencils), pencil sharpeners (not electronic), erasers,
glasses, watches (with clock function only) , eye drops, tissues, and handkerchief are allowed touse during the examination. Please take tissues out from their package.
2. During the “English competence exam,” it is permitted to bring in paper dictionaries (electronic
dictionary are not allowed.). However, medical dictionaries are not allowed in this exam.
3. Please be sure to refer to the attachment for information on the scope of the examination for
General medicine and life science.
4. Applicants for Advanced Medical Science Course, Advanced Medicine for Clinicians Course, orInterdisciplinary Medical Science and Innovation Course who have eligibility No.6 will take theessay exam instead of the exam on General medicine and life science.
3.

Location

Shiga University of Medical Science (Please refer to the “Campus Map” on page 12.)
Details will be sent together with the Examination Admission Card.

8

Result Announcement
10:00 am, Thursday, September 12, 2024 (as scheduled)
Successful applicants’ numbers will be announced on our homepage (https://www.shiga-med.ac.jp/), while“a letter of acceptance” will be sent to successful applicants.
We do not answer any inquiries regarding results by phone.

Enrollment Registration
1. Date and Time・At school
From 9:00 am to 5:00 pm on Thursday, September 19, 2024
・By postal mailDue by 5:00 pm, Friday, September 20, 2024
If you send documents via postal mail, please call the phone number given in item 2 below no later than
5:00 pm, Wednesday, September 18, 2024.
2.

Place of registration (postal address) and contact
Admissions Division, Entrance Examination Section
Shiga University of Medical Science
Seta Tukinowa-cho, Otsu City, Shiga 520-2192, Japan
Tel: +81-77-548-2071 (direct)

3.

Payment(1) Entrance fee: 282,000 yen(2) Tuition fee: 267,000 yen for the second half
① Successful applicants will be notified of information regarding tuition fees, including the amounts
and payment details.
② The tuition fee for the second half must be paid using the payment slip provided by SUMS before
the end of November , 2024.
③ When the tuition fee is revised during enrollment, the new fee shall be applied from the date therevision takes effect.

4.

Exemption of Payment
Exemption and deferred payment of entrance fee and tuition may be applicable, and procedures for thesewill be announced separately to successful applicants. However, due to budgetary constraints, there may

9be cases where exemptions are not possible, so please carefully consider your payment plan for entrance
and tuition fees.
5.

Documents to Be Submitted
Documents and other information required for the registration will be announced with the letter of
acceptance.

6.

Considerations(1) An Examination Admission Card will be necessary for the registration, so please be careful not to loseit.
(2) If you do not complete the registration by the above date, it will be considered as a withdrawal ofenrollment.

Screening of Eligibility for Application
If you apply based on any of the criteria 5-8 listed in Eligibility for Applicants, you must undergo thefollowing screening procedures to be certified as eligible to apply.
1.

Application Documents for Screening(1) If you apply under criteria 5, submit following items from ① to ④.
(2) If you apply under criteria 6 or 7, submit following items from ① to ⑥.
(3) If you apply under criteria 8, submit following items from ① to ④ and ⑦.
① Request for Screening of Eligibility for Application (designated form available)② Future research theme and research plan (about 700-800 words on an A4-size sheet)③ Academic Transcript (Prepared and sealed by the President (Dean) of the school attended.(Japanese or English)

If you have completed/will complete a master’s program, please also

submit an academic transcript prepared and sealed by the President (Dean) of the graduate
school.)④ Envelope for sending a screening result: Please write your name/address, and attach postage
stamps equivalent to 344 yen on the front of a “Nagagata No. 3” size envelope (120 × 235 mm)⑤ Letter of recommendation (Prepared by the President (Dean) of the school attended. However, if
you apply for NCD Course, please use the Form C.)⑥ Curriculum (copy) and syllabus (copy) of the school currently attended⑦ Letter of recommendation (Prepared by the supervisor of a research/medical institution, etc.
However, if you apply for NCD Course, please use the Form C.)

2.

Period of Application

10

Monday, July 1 to Friday, July 5, 2024 (must arrive by 5:00 pm)
3.

Place to Submit the Application Documents
The place and address for submission are the same as “2. Address to Submit Application Documents andInquiry” on page 5.
If you send them by postal mail, send via “simplified registered mail” and write “Enclosed with therequest for Screening of Eligibility for Application for Doctoral Program” in red ink on thefront of the envelope. If you submit them at school, please bring it to the Admissions Division between
9:00 am and 5:00 pm.

4.

Eligibility Screening
Eligibility screening is conducted based on documents you will submit. However, an interview may berequired, and in that case, the applicant will be notified.

5.

Screening Results
Screening results will be sent to the applicants by Friday, July 19, 2024.
If you are eligible, please follow the application procedure stated in this guideline (refer to page 5.)
Please note that documents submitted for the Screening of Eligibility can be used for the subsequent
application procedure, so there is no need to submit them in duplicate.

Handling of Private Information
Please be advised that private information obtained by the school during the admission process will behandled in accordance with the following conditions.
1.

Private information will be handled in accordance with the “Act on the Protection of Personal
Information” and “Protection of Personal Information Regulations Held by the National University
Corporation, Shiga University of Medical Science (as translated).”

2.

Name, address, and other private information on submitted application documents, etc., will be usedfor (1) applicant selection (application processing and selection), (2) notification of successful
applicants, and (3) registration for enrollment.

3.

Examination results obtained through applicant selection will be used to develop materials for futureapplicant selection.

4.

Enrolling students’ private information provided in application documents, etc. will be used for (1)teaching (student registration, study guidance, etc.), (2) support for students (health management,
application for scholarship, etc.), and (3) administration regarding tuition payment.

11Campus Map“Idai Nishimon” Bus Stop

Woodland Conservancy

West
Gate

SportsGroundParking

９Gymnasium

３２Parking

６

４

University Hospital

１

５
８

Woodland Conservancy

７
Parking

Main Gate

East Gate“Daigaku Byoin” Bus Stop

“Shiga Arena” Bus Stop

(1) General Education and Research
Building

Transportation

JR Minami Kusatsu
Station

JR Tokaido Honsen(2) Medical Science Research
Building

National Route No. 1
JR Seta Station
Keiji Bypass(3) Basic Medicine Laboratories andLecture Halls

Tokaido Shinkansen
Kusatsu-Tanakami IC(4) Student Center
Meishin Expressway(5) Clinical Medicine Education andResearch Building(6) Clinical Lecture Halls

Culture Zone
Seta-Nishi IC(7) Administration Building and HealthManagement Center

Idai Nishimon
Seta-Higashi IC(8) Library and Multimedia Center(9) School of Nursing Building

文○
Ritsumeikan University

Shiga University of Medical
Science文○
Ryukoku University

Higashi Otsu Senior High School

Take a route bus heading for “Shiga Idai” in front of Seta
Station of JR Tokaido Honsen (Biwako Line) and get off at“Idai Nishimon” (takes about 15 min)12

Overview of the Graduate School of Medicine,
Doctoral Program (Medical Science)
PurposeThe purpose of this Graduate School of Medicine (Doctoral Program) is to grow excellent researchers who haveadvanced research ability required to be independently engaged in creative research activities, high academic
expertise that serves as a foundation for the former ability, and a sense of humanity; and our mission is to dedicate
ourselves to the advancement of medical science and improvements in social welfare.

Structure⚫ Four courses are available under one major.
⚫ “Oncology Specialist Training Course” and “Forensic Generalist, Forensic Specialist Training Course” hasbeen established within Advanced Medicine for Clinicians Course.

Advanced Medical Science Course
Advanced Medicine for Clinicians Course
Advanced Medicine for Clinicians Course
Oncology Specialist Training Course
Interdisciplinary Medical Scienceand Innovation Course

Forensic Generalist,
Forensic Training Specialist Course

NCD Epidemiology Leader’s Course

Four courses are offered to grow (1) medical researchers and advanced clinicians who can perform unique andleading-edge research based on high academic expertise and broad knowledge in general medicine; (2) people withinterdisciplinary knowledge and research abilities, for example, on medicine and engineering or medicine andbiotechnology; and (3) physicians and medical researchers with high expertise, a sense of humanity, and high ethicalstandards.

Advanced Medical Science Course:
Students engage in medical research from basic medicine to clinical medicine and develop a doctoral dissertation
to obtain the degree.
1.

Development of excellent researchers who have the advanced research abilities needed to be independently
engaged in creative research activities, high expertise that serves as a foundation for the former abilities, highethical standards, and a sense of humanity.

2.

Development of highly motivated people who have an enthusiastic and inquisitive mind with creativity andwho try to solve a variety of medical issues ranging from basic medicine to clinical medicine.

3.

Development of physicians/medical researchers who have the latest knowledge and research abilities sufficient- 13 -

to play an active role in the international arena.
Advanced Medicine for Clinicians Course:
Students engage mainly in clinical research while working to be qualified as a specialist and develop a doctoral
dissertation to obtain their degree.
1.

Development of advanced clinicians who have excellent research abilities, advanced clinical skills, high ethicalstandards, and a sense of humanity.

2.

Development of medical research to develop new diagnostic and therapeutic methods with the aim of adopting
research outcomes in clinical medicine from clinical sites.

3.

Study on medical ethics and legal theories with a focus on clinical research and the development of people
who can be successful leaders in clinical sites.

Interdisciplinary Medical Science and Innovation Course:
Students study about the creation of a new academic discipline and medical innovation through the integration of
medicine and other fields of study and develop a doctoral dissertation to obtain their degree. Classes are considered
for those who have graduated from a department other than a medical school.
1.

Development of researchers who have interdisciplinary knowledge and high research skills that transcend
conventional academic disciplines, such as medicine, engineering, and biotechnology, combined with highethical standards and a sense of humanity as clinicians.

2.

Development of people who lead innovations in medical science and practice with interdisciplinary knowledge
and high research ability.

3.

Development of researchers who have not only broad knowledge on basic and clinical medicines but alsointerdisciplinary perspectives and research abilities to become successful in research institutions of college,
private companies, and other organizations.

NCD Epidemiology Leader’s Course:
Students research about NCD (Non-Communicable Disease) and develop a doctoral dissertation to obtain the
degree.
1.

Development of well-balanced NCD leaders who possess medical knowledge concerning NCD, expertise inepidemiological methodology and biostatistics, as well as the ability to formulate novel solutions for improving
public health in Asia.

2.

Development of global leaders who are internationally minded, proficient in English, and capable of engaging
in logical discussion.

3.

Development of academic leaders with first-rate research skills based on extensive experience in large-scale
epidemiologic research studies and international collaborative research.

4.

Development of dynamic leaders capable of playing an active role at the front line of health-related industries
and government agencies focused on public health issues.

- 14 -

List of Classes and Number of Credits
Refer to Appendix 1.
For Oncology Specialist Training Course and Forensic Generalist, Forensic Specialist Training Course pleaserefer to “Student Application for Oncology Specialist Training Course” and “Forensic Generalist, Forensic Specialist
Training Course,” respectively.

Major Study Themes of Faculty
Refer to Appendix 2.

Study Guide
Advanced Medical Science Course, Advanced Medicine for Clinicians Course, Interdisciplinary
Medical Science and Innovation Course:
1. Over the first, second, and third years, students must earn at least 30 credits in total, including 14 credits fromcompulsory subjects; and 4 credits from compulsory subjects among course subjects; and 12 or more credits
from practice subjects.
2. In the third and fourth years, students should dedicate themselves in voluntary research activities, while receiving
research guidance suitable for their research themes from their academic advisors, to nurture the advanced
research abilities needed to be independently engaged in creative research activities and expertise that serves asfoundations for the former abilities.
3. For Oncology Specialist Training Course and Forensic Generalist, Forensic Specialist Training Course, pleaserefer to “Student Application for Oncology Specialist Training Course” and “Student Application for Forensic
Generalist, Forensic Specialist Training Course,” respectively.
NCD Epidemiology Leader’s Course:
1.

During the four years of the program, students are required to earn 18 credits in the compulsory subjects andtwo credits in the elective subjects in core area; two credits in the elective subjects in supplemental area; andeight credits in the compulsory subjects and two credits in the elective subjects of practicum.

2.

Starting in the second year, students will engage in their own research under the guidance of an academic
advisor. They will participate in a training program at another institution in order to gain practical knowledge inassociation with their research subject. Through these experiences, students will acquire advanced researchskills and become capable of conducting research independently and creatively.

Special Exception of Education Methods
In our Graduate School of Medicine (Doctoral Program), the “Special Exception of Education Method” has been
adopted according to Article 14 of Graduate Schools Establishment Standards. We provide classes and researchguidance not only during the daytime, but also in the evening and other special hours or periods so that workers cancomplete a program and receive education and research guidance while maintaining their job. (It does not apply to theProject for Reducing the Burden of Non-Communicable Disease (NCD) in the Asian Pacific Region.)- 15 -

Grant of Academic Degree
1.
2.

3.

The standard term of study is four years.
A doctoral degree (medicine) is granted.
The degree is granted to those who have stayed in this graduate school for four years or more, earned 30 credits ormore in accordance with the above Study Guide, and passed a Qualifying Examination, furthermore passed a
dissertation review and a final examination after receiving the necessary research guidance. However, those whohave stayed in this graduate school for three years or more, achieved extraordinary research results, and fulfilledcertain requirements may be granted a degree even if they stayed in the school for less than four years.

- 16 -

Appendix 1

Advanced Medical Science Course, Advanced Medicine for Clinicians Course,
Interdisciplinary Medical Science and Innovation Course
List of Classes and Number of Credits

Practice subjects

Course subjects

Common subjects

Grade

Basic Science Fundamentals &Multidisciplinary SeminarsⅠ
Basic Science Fundamentals &Multidisciplinary SeminarsⅡFoundational
education

1-2

3

1-2

3

Technical Seminar

1-2

Bioethics and Medical Ethics

1-2

1

Fundamentals of Epidemiology andMedical Statistics

1-2

1

Integrated Basic and Clinical SeminarⅠ

1-2

2

Integrated Basic and Clinical SeminarⅡ

1-2

2

1-2

Clinical Research
Advanced
Skills for Epidemiology and Medical
Medicine for
Statistics
Clinicians Course
Medical Ethics and Law

1-2

1-2

1

Biomedicine
Interdisciplinary
Medical Science Genome Scienceand Innovation Bioinformatics
CourseInfectious Diseases

1-2

1

1-2

1

1-2

1

1-2

1

Compulsory2

1-2

Compulsory
2

2

1-2

1

Compulsory

Compulsory

Practice in Cellular Physiology A

1-3

2

Practice in Cellular Physiology B

1-3

2

Practice in Developmental andFunctional Anatomy A

1-3

2

Practice in Developmental andFunctional Anatomy B

1-3

2Practice in Stem Cell Biology A

1-3

2

Practice in Stem Cell Biology B

1-3

2

Practice in Regulation of Gene
Expression A

1-3

2

Practice in Regulation of Gene
Expression B

1-3

2

Practice in Molecular Cell Biology A

1-3

2

Practice in Molecular Cell Biology B

1-3

2

Practice in Molecular Neuroanatomy A

1-3

2

Practice in Molecular Neuroanatomy B

1-3

2Practice in Diagnostic Pathology A

1-3

2

Practice in Diagnostic Pathology B

1-3

2

17

Note

2

Advanced Medical Pioneer Seminar
Science Course Frontier Medical Research Method

CommonPractice

Class title

Exercise

Subject classification

LectureCredits

Elective

Appendix 1

Practice subjects

CommonPractice

Exercise

Subject classification

LectureCredits
Class title

Grade

Practice in Pathology and Immunology A

1-3

2

Practice in Pathology and Immunology B

1-3

2

Practice in Molecular Pharmacology A

1-3

2

Practice in Molecular Pharmacology B

1-3

2

Practice in Occupational Health A

1-3

2

Practice in Occupational Health B

1-3

2Practice in Legal Medicine A

1-3

2

Practice in Legal Medicine B

1-3

2

Practice in Cardiology A

1-3

2

Practice in Cardiology B

1-3

2

Practice in Respiratory Medicine A

1-3

2

Practice in Respiratory Medicine B

1-3

2

Practice in Gastroenterology A

1-3

2

Practice in Gastroenterology B

1-3

2

Practice in Hematology A

1-3

2

Practice in Hematology B

1-3

2

Practice in Endocrinology, Metabolism& Nephrology A

1-3

2

Practice in Endocrinology, Metabolism& Nephrology B

1-3

2

Practice in Neurology A

1-3

2

Practice in Neurology B

1-3

2

Practice in Pediatrics A

1-3

2

Practice in Pediatrics B

1-3

2

Practice in Psychiatry A

1-3

2

Practice in Psychiatry B

1-3

2Practice in Dermatology A

1-3

2

Practice in Dermatology B

1-3

2

Practice in Gastrointestinal Surgery, andBreast, Pediatric and General Surgery A

1-3

2

Practice in Gastrointestinal Surgery, andBreast, Pediatric and General Surgery B

1-3

2Practice in Cardiovascular Surgery A

1-3

2

Practice in Cardiovascular Surgery B

1-3

2Practice in General Thoracic Surgery A

1-3

2

Practice in General Thoracic Surgery B

1-3

2Practice in Orthopaedic Surgery A

1-3

2

Practice in Orthopaedic Surgery B

1-3

2Practice in Hands-on Educational
Program in Neurosurgery A

1-3

2

Practice in Hands-on Educational
Program in Neurosurgery B

1-3

2

18

Note

Elective

Appendix 1

Practice subjects

CommonPractice

Exercise

Subject classification

LectureCredits
Class title

Grade

Practice in Otorhinolaryngology-Headand Neck Surgery A

1-3

2

Practice in Otorhinolaryngology-Headand Neck Surgery B

1-3

2Practice in Obstetrics and Gynecology A

1-3

2

Practice in Obstetrics and Gynecology B

1-3

2

Practice in Urology A

1-3

2

Practice in Urology B

1-3

2

Practice in Ophthalmology A

1-3

2

Practice in Ophthalmology B

1-3

2

Practice in Anesthesiology A

1-3

2

Practice in Anesthesiology B

1-3

2

Practice in Radiology A

1-3

2

Practice in Radiology B

1-3

2

Practice in Oral and Maxillofacial
Surgery A

1-3

2

Practice in Oral and Maxillofacial
Surgery B

1-3

2

Practice in Clinical Laboratory Medicine
A

1-3

2

Practice in Clinical Laboratory Medicine
B

1-3

2

Practice in Critical and Intensive Care
Medicine A

1-3

2

Practice in Critical and Intensive Care
Medicine B

1-3

2

Practice in Medical Oncology A

1-3

2

Practice in Medical Oncology B

1-3

2

Practice in Primary Care Medicine A

1-3

2

Practice in Primary Care Medicine B

1-3

2

Practice in Plastic & Reconstructive
Surgery A

1-3

2

Practice in Plastic & Reconstructive
Surgery B

1-3

2

Practice in Clinical Cancer
Pharmacology A

1-3

2

Practice in Clinical Cancer
Pharmacology B

1-3

2

Practice in Neuropathobilogy A

1-3

2

Practice in Neuropathobilogy B

1-3

2

Practice in Neuropharmacology A

1-3

2

Practice in Neuropharmacology B

1-3

2

Practice in Neuroscience A

1-3

2

Practice in Neuroscience B

1-3

2

19

Note

Elective

Appendix 1

Practice subjects

CommonPractice

Exercise

Subject classification

LectureCredits
Class title

Grade

Practice in Laboratory Animal Science A

1-3

2

Practice in Laboratory Animal Science B

1-3

2

Practice in Epidemiology Research A

1-3

2

Practice in Epidemiology Research B

1-3

2

Practice in Biocommunication Research
A

1-3

2

Practice in Biocommunication Research
B

1-3

2

Practice in Regenerative Medicine
Research A

1-3

2

Practice in Regenerative Medicine
Research B

1-3

2

20

Note

Elective

NCD Epidemiology Leader’s Course
List of Classes and Number of Credits
Credits
Area

Cluster

Subject

Grade
LectureFundamentals of Public Health1

Exersice

Practice2

Public HealthCompulsory
Health Administration and Public Health
Law

2

2

Fundamentals of Epidemiologic Methods

1

2

1

2

Fundamentals of Medical Statistics

1

2

Epidemiology of NCDs

1

2

Compulsory

Social Epidemiology

22Compulsory

Workshop for Discovering Asian Culture andEthics1

Epidemiology andFundamentals of Clinical Trials
Medical Statistics

Core

Elective/Required/semiobligatory
subjects

Compulsory

Advanced Topic of
Epidemiology

International
Communication

Compulsory
Presentation and debates

Supplemental

2

2

Clinical Medicine Clinical medicine of NCDs
Medical innovation from bench tocommunity

2

1

2

2

2

Elective

Medical Innovation

PracticumElective
Industrial Health1

Thesis preparation

2

4

Global Research Training

2

2

Research and Development in the Health
Related Industries22

Fieldwork at an Asia-Pacific region

3

2

Presentaion at academic conferences

3

4

21

2

Compulsory

Elective

Compulsory

Appendix 2
Major Study Themes of Faculty(As of May 2024)
Department / Centre

Division / Unit

Title

Name

Major Study Themes
1. Study on nanomaterials, nanostructures and surfaces

Professor

MERA Yutaka

2. Development of nano-spectroscopy
3. Medical application of nanotechnology
1. Research for optical properties of nano-,bio-materials

Division of Physics

2. Research for material science using diffraction, microscopy, andAssociate
Professor

NARUSE Nobuyasu

spectroscopy
3. Physics research contributing to environmental science,
agriculture, disaster prevention, and medical science
4. Research for science education
1. Development of medical materials based on supramolecularchemistry

Department ofFundamental Biosciences

Division of Chemistry

Professor

FURUSHO Yoshio

2. Construction of soft materials utilizing formation of organic salt
bridges driven by hydrogen bonding
3. Design and Synthesis of Functional Polymers
1. Molecular basis of immune cell trafficking

Professor

HIRATA Takako

2. Control of lymphocyte migration to the skin and mucosa
3. Immune regulation by cytoskeleton-associated proteins
1. Immunometabolism and redox signaling in autoimmunity

Division of Biology

2. The mechanism of CD8+ regulatory T cell differentiation and
Associate
Professor

SATOOKA Hiroki

the application of CD8+ regulatory T cell for autoimmune disease
treatment.
3. Non-lymphoid tissue-specific immune regulation

Division of Mathematics

Associate
Professor

KAWAKITA Motoko

1. Algebraic curves with many rational points
1. research on bioethics (clinical ethics, research ethics, public health ethics)

Division of Philosophy
and Ethics

Professor

OKITA Taketoshi

2. research on the concept of care and responsibility
3. research on ethical issues related to HIV infection and other infectious diseases
1. Spatial cognition and language understanding

Division of Psychology
Department of Cultureand Medicine

Associate
Professor

KOJIMA Takatsugu

2. Affective information processing
3. Non-verbal cognition

Division of English

Professor

KATO Yutaka

1. International comparative research on bioethics
2. Research on medical and nursing English education
1. Anthropological studies on ethnic minorities of P.R.China

Division of Cultural
Anthropology

Professor

KANESHIGE Tsutomu 2. Anthropological studies on Fengshui
3. Anthropological studies on merit and merit-making
1. Analysis of the function of the brain phospholipid to the behavior
2. Analysis of the pathogenesis of nonalcoholic fatty liver disease related toProfessor

UDAGAWA Jun

in utero environment
3. Study on the relationship between hand structure and grasping

Division of Anatomy andCell Biology

function
1. Elucidation of the molecular mechanisms underpinning DOHaD
Special Contract
Associate
Professor

Department of Anatomy

UCHIMURA Yasuhiro(developmental origins of health and disease) hypothesis
2. Elucidation of the function of the genes involved in the onset ofsarcopenia
1. Analysis of brain morphogenesis

Professor

KATSUYAMA Yu

Division of
Neuroanatomy

2. Analysis of mechanisms of maintenance and differentiationof the stem cells
3. Analysis of model animals of psychiatric diseases.
1. Stem cell aging and tissue homeostasis

Associate
Professor

KANEDA Hayato

2. Search for biomarkers of age-related diseases
3. Brain morphogenesis
1. Analysis of the generation,maintenance,and differentiation ofneural stem cells

Division of Integrative
Physiology

Professor

HITOSHI Seiji

2. Development of regenerative therapy strategy for the damaged
central nervous system
3. Understanding the pathogenesis of psychiatry diseases

Department of Physiology

1. Neural circuit mechanisms underlying motivation, decision-making, and attention
2. Computational algorithms of neural activities related to motivation, decision-making
Division of Systems
Physiology

Professor

OGAWA Masaaki

and attention
3. Translational research that contributes to the understanding, diagnosis, and treatmentof psychiatric disorders with impaired motivation, decision-making, and/or attention

22Appendix 2(As of May 2024)
Department / Centre

Division / Unit

Title

Name

Major Study Themes
1. Epigenetic regulation of gene expression and cancer development

Professor

AGATA Yasutoshi

Division of Molecular
Physiological Chemistry

2. Regulation of gene expression and cancer development bychromosome dynamics
3. Regeneration of cancer specific T cells from iPS cells
1. Molecular mechanism of antigen receptor gene rearrangement

Associate
Professor

Department ofBiochemistry andMolecular Biology

TERADA Koji

in lymphocytes
2. Gene-reglation for lymphocyte development
1. Signal transduction reseach and genetic analysis in the field ofProfessor

OGITA Hisakazu

cancer biology and cardiovascular diseases
2. Molecular mechanism of cell adhesion

Division of Molecular
Medical Biochemistry

1. Signal transduction and cell-cell communication in cancer andAssociate
Professor

SATO Akira

inflammatory diseases.
2. Adult diseases triggered by aberrant regulation of Wnt signaling.

Professor
Division of Human
Pathology

KUSHIMA Ryoji

1. Gastrointestinal pathology
2. Diagnostic pathology
1. Study on the progression potential of non-invasive cancer of

Associate
Professor

NAKAYAMA Takahisa

gastrointestinal tract
2. Research on antitumor therapy based on synthetic lethality
1. Development of vaccines and therapeutic agents against influenza
virus

Department of Pathology

Professor

ITOH Yasushi

Division of Pathogenesis
and Disease Regulation

2. Research on genetic diseases and aging using a non-humanprimate model
3. Analysis of immune responses using cynomolgus macaques

Division of Microbiology
and Infectious Diseases

Associate
Professor

ISHIGAKI Hirohito

Associate
Professor

TANBE Yukihiro

1. Immunology with using a primate model especially for tumor,transplantation, and infectious disease
1. Physiological function(s) of cancer-related genes.
2. Search for novel anti-tumor compounds.
1. Molecular mechanism and pathophysiological role of ectodomain
shedding

Professor

NISHI Eiichiro

2. Regulatory role of transcriptional coregulator in metabolism
3. Role of metallopeptidases in cardiovascular disease, cancer andinflammatory diseases

Department ofPharmacology－

1. Molecular mechanism and pathophysiological roles of heart rate
control by the multifunctional protease.
Associate
Professor

OHNO Mikiko

2. Usefulness of the novel biomarker for the early detection of ACS
3. Regulatory role of protease in megakaryocyte maturation andplatelet production
4. Role of metalloprotease in Alzheimer’s disease
1. Prevention of Work-related Musculoskeletal Disorders

Division of Occupational
and Environmental
HealthSpecialContract
Associate
Professor

2. Health and Safety of Persons with Disabilities (Prevention of
KITAHARA Teruyo

secondary disorders)
3. Support for Balancing Treatment and Work
4. Social Barriers and Health of People with Disabilities or Information
Vulnerable Populations

Department of Social
Medicine

1. Amalysis of traffic injuries
Professor

HITOSUGI Masahito

Division of Legal
Medicine

2. Pathophysiological analysis for sudden death cases due tothrombosis
3. Preventive medicine for deaths of external causes
1. Forensic Toxicology, clinical toxicology, physiology of abuse drugs

Associate
Professor

NAKAMURA Mami

2. Virtopsy, postmortem computed tomography
3. Out-of-hospital death by infectious disease including COVID-19
1. Coronary reconstruction in ischemic heart disease

Professor

NAKAGAWA Yoshihisa 2. Primary and secondary prevention for atherosclerosis
3. Optimal antithrombotic therapy

Division of
Cardiovascular Medicine

1. Elucidation of the pathophysiology of heart failure
Associate
Professor

SAKAI Hiroshi

2. Research on diagnosis and treatment of pulmonary hypertension
3. Research on diagnosis and treatment of cardiac amyloidosis

Professor

NAKANO Yasutaka

1. Structure and function relationship of the lung
2. Structure and function relationship of respiratory diseases
1. Research on the pathophysiology of severe asthma

Department of Internal
Medicine

Division of Respiratory
Medicine

Associate
Professor

YAMAGUCHI Masafumi 2. Study on the pathophysiology and treatment of chronic intractable
cough
1. Research on body composition of COPD

Associate
Professor

KINOSE Daisuke

2. Research on lung structure and function in COPD
3. Research on the gut microflora of COPD

Associate
Professor
Division of
Gastroenterology

INATOMI Osamu

1. Pancreatic fibrosis in pancreatic cancer and chronic pancreatitis
2. New development of endoscopic device in ERCP
1. Mucosal immunity in inflammatory bowel disease

Associate
Professor

NISHIDA Atsushi

2. The gut microbiota in inflammatory bowel disease
3. Cytokine network in inflammatory bowel diesase

23

Appendix 2(As of May 2024)
Department / Centre

Division / Unit

Title

Name

Major Study Themes
1. Mechanism of immune response after hematopoietic stem cell

Division of Hematology

Professor

MURATA Makoto

transplantation
2. Prognostic factor for hematological diseases
3. Development of novel cellular therapy
1. Pathogenesis of diabetic nephropathy

Professor
Division of Diabetology,
Endocrinology and
Nephrology

KUME Shinji

2. Pathogenesis of chronic kidney disease
3. Renal energy metabolism
1. Pathogenesis of diabetic kidney disease

Associate
Professor

YAMAHARA Kosuke

2. Regulatory mechanisms of autophagy in the kidney
3. Renal energy metabolism
1. Molecular targeted therapy for amyotrophic lateral sclerosis

Department of Internal
Medicine

2. Cell biological analysis of neurodegenerative diseases
Professor

URUSHITANI Makoto

3. Noninvasive diagnosis of neurological diseases
4. Molecular pathology of cerebrovascular diseases
5. Functional brain image analysis of Nerve rehabilitation
1. Engineering the novel molecular therapies with cell and tissue

Division of Neurology

specific targeting
Associate
Professor

TERASHIMA Tomoya

2. Application to the regenerative therapies with reprograming of bonemarrow-derived cells
3. Analysis of the relation between bone marrow-derived cells andneurological diseases

Associate
Professor

YAMAKAWA Isamu

1. Electrodiagnosis in clinical neurology
2. Neurorehabilitation and Brain functional image
1. Molecular genetic analysis of hereditary unconjugatedProfessor

MARUO Yoshihiro

hyperbilirubinemia
2. Polymorphism of UDP-glucuronyltransferase and drug metabolism
3. Genetic analysis of congenital hypothyroidism

Associate
Professor
Department of Pediatrics

TAGA Takashi－

1. Clinical study for developing therapeutic approach of pediatric leukemia
1. Study on diagnosis and treatment of the atypical hemolytic uremic

Associate
Professor

SAWAI Toshihiro

syndrome
2. Elucidation of the disease mechanism of C3 glomerulopathy
3. Research on factors involved in complement dysregulation
1. Genetic back ground of prolonged hyperbilirubinemia in preterm

Associate
Professor

YANAGI Takahide

infants
2. Genetic back ground of bilirubin encephalopathy in preterm infants

Professor

Department of Psychiatry－

SpecialContract
Professor

OZEKI Yuji

1. Etiology and pathophysiology of schizophrenia
2. Cardiovascular adverse effect by psychotropics
1. Clinical research on sleep disorders

KADOTANI Hiroshi

2. Epidemiological research on sleep and mental health
3. Development and evaluation of wearable devices to analyze sleep
1. Etiology and pathophysiology of schizophrenia.

Associate
Professor

FUJII Kumiko

2. Mental illness with involuntary movemen.
3. Clinical studies of pregnant women with mental illness
1. Analysis of regulatory B cells on autoimmune diseases

Professor

FUJIMOTO Noriki

2. Investigation for the treatment of cutaneous mailgnant tumors
3. Gene editing for treatment of epidermolysis bullosa
1. T-cell Mediated Autoimmune Pathomechanism in Alopecia Areata and Psoriasis

Department of
Dermatology－

Associate
Professor

ARAKAWA Akiko

2. Effect of T-cell receptor-Antigen interaction on T-cell differentiation
3. T-cell Mediated Tumor Immunity in Melanoma and Angiosarcoma
1. Research for diagnosis and treatment of allergic skin diseases

Associate
Professor

TAKAHASHI Toshifumi

2. Research for detecting the genomes of pathogens in infectious skindiseases
3. Research for the pathogenesis and treatment of genetic skin diseases

24Appendix 2(As of May 2024)
Department / Centre

Division / Unit

Title

Name

Major Study Themes
1. Clinical study for the prevention of post operative complications inpancreatectomy
2. Development of immunotherapies for gastrointestinal diseases

Professor

TANI Masaji

3. Study of the pancreatic function
4. Evaluation of mechanisms for the metastasis
5. Study of the intervention for surgical skill

Division of
Gastrointestinal Surgery,and Breast, Pediatric,
and General Surgery

6. Interaction between cancer cells and fibroblasts
1. Study for Cancer fibrosis.
Associate
Professor

MIYAKE Tohru

2. Study for Cancer metastasis.
3. Study for peri operatire management in Colorectal Surgery.

Associate
Professor

ISHIKAWA Hajime

1. Research on improving the safety of hepatectomy
2. Analysis of physiological response to cancer immunotherapy
1. Study on nutritional status after gastric cancer surgery

Associate
Professor

KAIDA Sachiko

2. Research on the usefulness and safety of robot-assisted gastrectomy
3. Research on automatic recognition of the stomach and surrounding
blood vesselsusing artificial intelligence (AI)
1. Long term outcome of total arterial off-pump CABG

Professor

SUZUKI Tomoaki

Department of Surgery

2. The outcome of total arch replacement under mild hypothermia
3. Technical aspect or long-term durability of mitral valve repair
4. Type A aortic surgery: optimal procedure or long-term remodeling
1. Minimally invasive surgery with VATS for chest diseases
2. A study of the operation method for lung cancer
3. da Vinch® robotic surgery in general thoracic surgery

Associate
Professor

HANAOKA Jun

4. A study of the identification technique of theinterlobar/intersegmental plane
5. Evaluation of pulmonary function before and after lay resection using
dynamic X-ray apparatus

Division of
Cardiovascular Surgery
and Thoracic Surgery

1. Uniportal video-assisted thoracoscopic surgery for non-small celllung cancer
2. Surgical navigation system for non-small cell lung cancer
Associate
Professor

OSHIO Yasuhiko

3. 8K endoscopic system for thoracic surgery
4. New method to detect and repair intraoperative pulmonary air
leakage
5. Antitumor immune response and tumor microenvironment
1. Study of long-term outcome of thoracic aortic aneurysm
2. Surgical examination and long-term prognosis study for acute aortic

Associate
Professor

TAKASHIMA Noriyuki

dissection
3. Examination of arterial wall extensibility and clinical application
4. Study of surgical procedure and long-term outcome of aortic stenosis
1. Improvement of clinical output in arthroscopic shoulder surgery

Professor

IMAI Shinji

2. Improvement of clinical output in shoulder arthroplasty
3. Regenerative medicine for injures of articular cartilage and spinal
cord
1. Research for the ossification of the spinal ligaments

Associate
Professor

MORI Kanji

2. Research for the diagnosis and treatment for the disease with spineand spinal cord
3. Research for bone matabolism

Department ofOrthopaedic Surgery－

1. Research for ossification process in patients with ossification of
Associate
Professor

YAYAMA Takafumi

spiual ligament
2. Pathological analysis for hypertrophy of ligament tissue
1. Development of joint degenerative disease diagnostic method andsuppressive therapy by comprehensive analysis of cell membrane

Special Contract
Associate
Professor

ion channels.
KUMAGAI Kosuke

2. A comparative study of drug use during the acquisition of low diseaseactivity in rheumatoid arthritis patients.
3. Correlation between TKA postoperative satisfaction andpatient-based outcome in RA patients.
1. Molecular pathophysiology and non-invasive diagnostic imaging ofatherosclerosis
2. Molecular pathophysiology and non-invasive diagnostic imaging ofProfessor

YOSHIDA Kazumichi

cerebral aneurysm
3. Development of a novel surgical treatment for cerebrovasculardiseases

Department of
Neurosurgery

4. Epidemiology of cerebrovascular disease－

1. Research for the multidisciplinary treatment for glioma
Associate
Professor

FUKAMI Tadateru

2. Research for the safety and the risk of awake surgery
3. Research for the therapeutic indications about neuroendoscopic
surgery
1. Pathophysiology and treatment of mesial temporal lobe epilepsy

Associate
Professor

NITTA Naoki

2. Analysis of neurophysiological examination
3. Pathophysiology and treatment of brain tumors25Appendix 2(As of May 2024)
Department / Centre

Division / Unit

Title

Name

Associate
Professor

OWAKI Shigehiro

Major Study Themes

1. Diagnosis and treatment of voice disorder
2. Diagnosis and treatment of headandneck cancer
1. The mechanism and control of epithelial-derived airway allergic

Department ofOtorhinolaryngology-Headand Neck Surgery

Associate
Professor

KOHZAKI Hideaki

diseases
2. The pathophysiological analysis of eosinophilic chronic rhinosinusitis
3. The pathophysiological analysis of Japanese cedar pollen rhinitis
1. Study of eosinophilic inflammation in upper airway

Associate
Professor

TOJIMA Ichiro

2. The pathophysiological research in allergic rhinitis
3. Mucus production and its regulation in airway epithelium
1. Minimally invasive gynecologic surgery (hysteroscopic,

Professor

MURAKAMI Takashi

Female Pelvic Surgery
and Reproductive
Medicine

laparoscopic, and robotic surgery)
2. Endometriosis and adenomyosis
3. Reproductive endocrinology and infertility
1. Robotic-Assisted Surgery for Gynecological Tumors

Associate
Professor

AMANO Tsukuru

2. Elucidation of resistance to treatment of gynecological tumors usingorganoids
3. Mechanism of carcinogenesis of endometriosis
1. Elucidation of pathophysiology and development of treatment and prevention methods

Department of Obstetrics
and Gynecology

for cesarean scar syndrome
2. Elucidation of the pathogenesis and development of treatments for
Associate
Professor

TSUJI Syunichiroperinatal brain disorders
3. Diagnosis and treatment of cesarean scar syndrome

Maternal and Fetal
Medicine

4. The role of resident microglia to neonatal hypoxic ischemic
encephalopathy
1. Study on the association between ovarian cancer stem cells and resistance to treatment
Associate
Professor

TAKAHASHI Akimasa 2. Investigation of minimally invasive surgery for gynaecological surgery
3. Microimmune environment analysis of gynaecological cancers
1. Clinical research in robotic and laparoscopic surgery

Professor

KAGEYAMA Susumu

2. Development of new anti-cancer drugs for urologic malignancy
3. Proteomics research in urologic oncology
1. Surgery in pediatric urology (Reseach for plastic and laparoscopic surgery)

Associate
Professor

JOHNIN Kazuyoshi

2. Reserch for voiding dysfunction in children
3. Application of MRI imaging in pediatric urology

Department of Urology－

1. Clinical research in urological robotic surgery
Associate
Professor

YOSHIDA Tetsuya

2. Clinical research of nephron-sparing surgery for renal tumors
3. Study of systemic therapy for advanced renal cancer
1. Complement control in kidney transplant rejection

Associate
Professor

YAMANAKA Kazuaki

2. Control of donor-specific antibodies in kidney transplantation
3. Analysis of factors associated with renal fibrosis in chronic antibody-mediatedrejection after kidney transplantation.

Associate
Professor
Department ofOphthalmology

SAWADA Osamu

1. Pharmacokinetics of intravitreal agents
2. Treatment for diabetic macular edema
1. Treatment Prediction Model for Retinopathy of Prematurity Using Artificial Intelligence

Associate
Professor

OBATA Shumpei

2. Pathophysiology of Retinopathy of Prematurity
3. Pharmacokinetics of intravitreal agents in macaque monkeys

Professor

KITAGAWA Hirotoshi

1. Multimodal in vivo monitoring of ischemia reperfusion injury
2. Cardioprotection by anesthetic agents and opioids
1. Elucidation of molecular basis for the mechanisms underlying
cardioprotective effect of anesthetics, focused on Ca2+ transport
proteins.
2. Investigation of modulatory effects of anesthetics on cardiac

Associate
Professor

KOJIMA Akiko

pacemaker function.
3. Electrophysiological and molecular biological analyses for theinteraction between anesthetics and ion channels.
4. Investigation of modulatory effects of anesthetics on ionicmechanisms involved in arrhythmogenesis.

Department ofAnesthesiology－

1. Elucidating the brain mechanisms of pain using functional brain
imaging
Associate
Professor

IWASHITA Narihito

2. Multidisciplinary treatment for chronic pain
3. Development of minimally invasive treatment using pulse
radiofrequency method
1.Elucidation of the intracerebral mechanism of chronic pain using brain MRI for
small animals (basic research)
2.Elucidation of the analgesic mechanism of Japanese herbal medicine (basic research)

Associate
Professor

NAKANISHI Miho

3.Pathological evaluation and treatment effects of multidisciplinary treatment,
drug therapy, in chronic pain patients (Clinical research)
4. Optimal conditions and long-term prognosis of peripheral nerve block using pulsed
radiofrequency (Clinical research)

26

Appendix 2(As of May 2024)
Department / Centre

Division / Unit

Title

Name

Major Study Themes
1. Study for pathophysiology of central nerves system disease andProfessor

WATANABE Yoshiyuki

functional imaging using MRI and CT.
2. Artificial intelligence for medical imaging.
3. Human fluid flow imaging using MRI.
1. Difference in tracheal diameter changes during deep breathing in asupine position between restrictive ventilator impairment patients,
obstructive ventilator impairment patients and normal respiratory
function patients using dynamic chest radiography

Associate
Professor

SONODA Akinaga

2. Difference in the pixel value change of lung field during deep
breathing between restrictive ventilator impairment patients,
obstructive ventilator impairment patients and normal pulmonary
function patients using dynamic chest radiography

Department of Radiology－

3. The effect of botulinum toxin A injection into the perirenal arterial
space to treat hypertension
1. Clinical research on radiation therapy for localized prostate cancer
Associate
Professor

KONO Naoaki

2. A retrospective study of the safety and efficacy of multi-targeted
stereotactic radiation for metastatic brain tumors
1. Research on improving the image quality of ultra-high-resolution CTof the lungs using artificial intelligence
2. Efforts to improve the accuracy of diagnostic imaging in the

Associate
Professor

KITAHARA Hitoshi

musculoskeletal radiology
3. Efforts to improve the accuracy of diagnostic imaging in thepediatric radiology
4. Efforts to improve the accuracy of diagnostic imaging in theneuroradiology
1. Effect of senescence-associated secretory phenotype（SASP）on bone

Professor

TAKAOKA Kazuki

microenvironment
2. Animal models of medication-related osteonecrosis of the jaw
3. The occlusal rehabilitation using jaw reconstruction and dental implants
1. Oral Cancer
2. Jaw Defomities and Cleft Palate

Department of Oral andMaxillofacial Surgery－

Associate
Professor

YAMORI Masashi

3. Anti-resorptive Agents-related Osteonecrosis of theJaw
4. Obstructive Sleep Apnea Syndrome
5. Periodontal Disease
6. Dental Implant
1. Elucidation of the mechanism of exposed bone wound healing anddevelopment of new tissue regeneration and repair materials

Associate
Professor

KOSHINUMA Shinya

2. Comprehensive analysis of oral flora
3. Elucidation of the relationship between maxillofacial morphology andsleep apnea syndrome and various diseases
1. Clinical application of genetic medicine
2. Analyzing the biological function RBICCI/FIP200

Department of ClinicalLaboratory Medicine－

Associate
Professor

CHANO Tokuhiro

3. Inventing novel strategies for cancer treatment,applied with novel
biomarkers
4. Drug development from targeting RAB39A

Diagnostic Pathology－

Associate
Professor

MORITANI Suzuko

1. Diagnostic pathology
2. Pathology of the breast and gynecological organs
1. Study on multimodal treatment of severe head injury

Professor
Department of Critical andIntensive Care Medicine

SHIOMI Naoto

2. Clinical research on brain death and resuscitation
3. Construction of pre-hospital emergency medical care system
4. End of life care in the Emergency medical field－

1. Study of cardiac dysfunction and arrhythmia under excessive stress
Associate
Professor

TSUJITA Yasuyuki

2. Study of septic organ dysfunction
3. Epidemiological study of cardiovascular shock

Associate
Professor

FUJINO Kazunori

1.Elucidation of the mechanism of multi-organ failure during invasion
1. Isolation and functional analysis of cancer-related genes.
2. Elucidation of molecular pathology of cancer by genomics andproteomics analysis.
3. Development of molecular targted drugs (small compounds, antibody,nucleic acid medicine)
Development and translational research of cancer vaccine andProfessor

DAIGO Yataro

immunomodulator drugs
4. Development of cancer peptide vaccines and immune-regulating drugs and their

Department of Medical
Oncology（Cancer Center）

translational research－

5. Development of cancer biomarkers and diagnostic systems based on molecular pathology
and their translational research towards personalized medicine
6. Activity of supporting research by establishing biobanking and using biospecimen
1. Analysis of mechanisms and development of treatment for metastasis
after surgery for gastrointestinal cancer
Associate
Professor

MURATA Satoshi

2. Control over the perioperative tumor microenvironment ingastrointestinal cancers
3. Development of immune cell therapy for solid cancers
4. Hyperthermic Intraperitoneal Chemotherapy (HIPEC)

27

Appendix 2(As of May 2024)
Department / Centre

Division / Unit

Title

Name

Major Study Themes
1. Medical diagnosis Avoiding diagnostic errors
2. Rural medicine

Professor

SUGIMOTO Toshiro

3. Clinical electrolyte acid-base abnormalities electrolyte; acid-baseabnormalities
4. Development of continuing professional development using ICT
1. Pathophysiology and therapy of chronic heart failure

Associate
Professor

OHNISHI Masato

2. Diagnosis and therapy of hypertension in primary care
3. Simulation-based instruction in healthcare professionals
1. Percutaneous endoscopic gastrostomy and management of that

Department ofComprehensive Internal
Medicine－patient.
Associate
Professor

ITOH Akihiko

2. Indication and complications of enteral nutrition.
3. Nutritional support team management and multi-occupation
collaboration.
1. Development of effective regional cooperation for medical care of the

Associate
Professor

MAENO Yasuhiro

diabetic patients
2. Development of effective educational techniques for the diabetic or
pre-diabetic people
1. Research for the efficacy of regional cooperation in respiratory

Associate
Professor

WADA Hiroshi

medicine examination.
2. Clinical examination of obstructive pulmonary disease.
1. Multimodality therapy for colorectal cancer

Professor

MEKATA Eiji

2. Development of the resin of the surgical instrument
3. Anticancer drug sensitivity test
4. Oncology (disease state, therapy and community cooperation)
1. Research on efficacy and safety of bariatric and metabolic surgery

Department ofComprehensive Surgery－

Associate
Professor

YAMAGUCHI Tsuyosi 2. Research on upper gastrointestinal surgery
3. Research on efficacy and safety of treatment of peptic ulcer
1. Study of gastrointestinal surgical stress

Associate
Professor

AKABORI Hiroya

2. Development of microwave surgical device
3. Clinical study of the operation method for pancreas

Associate
Professor

KITAMURA Naomi

1. Development of new endotoxin measurement method.
2. Postoperative analgesic effect for laparoscopic cholecystectomy.
1. Evaluation of percutaneous osteotomy for callus distraction

SpecialContract
Professor
Department of Plastic andReconstructive Surgery

ARATA Jun

2. Research of monitoring for tissue transfer
3. Research of survival rate and number of vascular anastomosis for
digital replantation－

1. Establishment of a novel scaffold which leads to the regeneration of
Associate
Professor

OKANO Junko

heterogenous tissues in deep wounds
2. Development of bacteriophage therapy for multi-antibiotic-resistantbacteria
1. Development of minimally invasive treatment for gastrointestinal
tumorsEndoscopy－

Associate
Professor

KIMURA Hidenori

2. Research on observation methods to improve the detection rate ofgastrointestinal tumors
3. Pathophysiological analysis in the development of gastrointestinal
tumors focusing on the gut microbiota

Blood Purification－

Blood Transfusion andCell Therapy Center－

Associate
Professor

KANASAKI Masami

Associate
Professor

MINAMIGUCHI Hitoshi

1. Blood purification
2. Mechanism of development of diabetic nephropathy
1. Phenotypic analysis of hematopoietic stem cell
2. Phenotypic analysis of leukemic stem cell
1.Perioperative nutritional support for esophageal cancer surgery

Clinical Nutrition－

Associate
Professor

TAKEBAYASHI Katsushi

2. The mechanism leading to postoperative recurrence of gastric andesophageal cancer
3. Multidisciplinary treatment strategy for esophageal cancer
1. Medical electronics

Medical Informatics andBiomedical Engineering－

Associate
Professor

SUGIMOTO Yoshihisa 2. Medical information system
3. Biomedical engineering for cardiology
1. Research on lipid transporters and lipid metabolism

Department ofPharmacotherapeutics（Pharmacy）

Professor

MORITA Shin-ya－

2. Development of methods for measuring lipids
3. Study of personalized medicine

Associate
Professor

IKEDA Yoshito

1. Research on lipid transporters
2.Research on metal transporters
1. Study of surgical stress

Professor
Medical Safety Section

SHIMIZU Tomoharu－

2. Development of new endotoxin measurement method
3. Studies of treatment for colorectal cancer and inflammatory bowel
diseases

Associate
Professor

MANDAI Ryoichi

1. In-hospital emergency system
1. A study of bone and soft tissue tumors

Rehabilitation Section－

Associate
Professor

KODAMA Narihito

2. Microsurgical approach for orthopedics and reconstructive surgery
3. A study of the idiopathic interosseous nerve palsy

28Appendix 2(As of May 2024)
Department / Centre

Division / Unit

Title

Name

Major Study Themes
1. Healthcare management

Professor

KASAMA Shu

2. Medical sociology
3. Pathophysiology using nuclear cardiology

Center for ClinicalResearch and Advanced
Medicine

1. A Recognition Investigation about Living Donor Transplantation:－

Analysis of the free description answer of the citizen by the Internet survey
Associate
Professor

KURATA Mayumi

2. Construction of the study entry applicant support system which
utilized the Internet
3. Critical Review of Priority Relative-Offers in Revision of Organ
Transplant Law
1. Hip and knee arthroplasty

Professor
Clinical Education Center
for Physicians

KAWASAKI Taku－

2. Epidemillogy of rheuamatoid arthritis
3. Locomotive rehabilitation

Associate
Professor

YAMAHARA Mako

1. Podocyte injury in diabetic kidney disease
2. Mechanism of progression of chronic kidney disease
1. Study of the pathogenesis involved in neurodegenerative disorders
and dementia

Professor

Molecular Neuroscience
Research Center

ISHIGAKI Shinsuke

Translational Research
Unit - Department of
Diagnostics andTherapeutics for Brain
Diseases

2. Therapeutics development for neurodegenerative disorders anddementia by antisense modulation
3. Development for novel biomarkers for neurodegenerative disorders
and dementia by behavioral test batteries and imaging analysis
1. Elucidation of Alzheimer's disease pathology for discovering novel
therapeutic targets.

Associate
Professor

YANAGISAWA Daijiro

2. Development of diagnostic biomarkers for dementia at very earlystage.
3. Research on the pathology, diagnosis, and disease-modifying
therapy of neurodegenerative diseases.
1. The research about primate ES/iPS cells
2. The research about the development of method to create geneticallyProfessor

EMA Masatsugu

modified monkeys and its application to human disease modeling
3. The research about primate early embryonic and placental
development
4. Molecular mechanism about angiogenesis

Research Center for
Animal Life Science

1. Therapeutic research of anti-ER stress drugs identified by a novel－

luminous probe.
2. Analysis of cellular pathology of sporadic amyotrophic lateral
Associate
Professor

MORIMURA Toshifumi

sclerosis focusing on translation products whose mRNAs arerecognized by TDP-43.
3. Early diagnosis and therapeutic research of Alzheimer’s disease byusing transgenic cynomolgus monkeys bearing amyloid-beta
precursor protein with disease associated mutations.

Pioneering Research
Division

Special Contract
Associate
Professor

1. Elucidation of pathological mechanism of Alzheimer's disease
HASHIMOTO Shokousing mouse models
2. Analysis of the effect of oxidative stress on brain homeostasis
1. Research theme includes mechanisms in ageing andneurodegenerative diseases such as Alzheimer’s Disease andmodulation by antioxidants such as palm oil vitamin E tocotrienol.
2. Modulation of the gut microbiome and metabolome and correlation

Medical Innovation
Research Center

International Joint
Research Division

SpecialContract
Professor

with cognitive function by tocotrienol in an APP/PS1 AD mouse
WAN ZURINAH
WAN NGAH

model.
3. Tocotrienol isomers effects on differentiated APP Swedish/PS1
transfected SH-SY5Y cells
4. Systems integration of the transcriptome, proteome and metabolomeof the hippocampus of AD APP/PS1 mice treated with tocotrienol(Collaboration with UKM)

Advanced Medical
Research andDevelopment Division

SpecialContract
Associate
Professor

１．Bending mechanisms for medical devices
YAMADA Atsushi

２．Flexible medical devices
３．Flexible robot mechanisms
４．Image guided surgeries
1. Elucidating the mechanism of the activation of hepatic stellate cells
in liver fibrosis.

Central ResearchLaboratory－

Associate
Professor

ASAHINA Kinji

2. Interaction of peritoneal macrophages and mesothelial cells covering
the internal organs in the peritoneal cavity.
3. Role of macrophages in pancreatic cancer.
1. Research on the pathogenesis of chronic obstructive pulmonary

Health Administration
Center－

Associate
Professor

OGAWA Emikodisease (COPD)
2. Clinical research using COPD cohort data

29

Appendix 2(As of May 2024)
Department / Centre

Division / Unit

Title

Name

Major Study Themes
1. Development of new strategy of catheter ablation for refractoryarrhythmias.
2. Studies on the mechanism of electrical defibrillation and theProfessor
Information Technology
and Management Center

ASHIHARA Takashi－

development of new defibrillator.
3. Application of human iPS cell-derived cardiomyocytes to the studies
on cardiovascular diseases.
4. Studies on cardiovascular diseases by in silico, artificial intelligence,and biomedical engineering.
1. studies on star formation process

Associate
Professor

MOTOYAMA Kazutaka 2. studies on evolution of interstellar medium
3. high performance computing

Professor

ITO Toshiyuki

1. Medical education
1. Gastric and esophageal carcinogenesis using various animal models

Education Center for
Medicine and Nursing

2. Analyses of extra-esophageal symptoms of GERD using reflux animal－
Professor

MUKAISHO Kenichimodels
3. Influence of bile acids on carcinogenesis and cancer progression
4. Morphology of cancer cells using a novel 3D cell culture system
1. Epidemiologic research of cardiovascular diseases

Professor

MIURA Katsuyuki

2. Preventive medicine of cardiovascular diseases
3. Nutritional epidemiology

Division of Preventive

1. Epidemiology of Diabetes mellitus and NCDs

Medicine
NCD Epidemiology
Research Center

Associate
Professor

KADOTA Aya

2. Epidemiology of Cardiovascular disease and subclinicalatherosclerosis
3. MWAS on Dementia
1. Statistical methods for epidemiologic researches

Division of Medical
Statistics

Associate
Professor

HARADA Akiko

2. Statistical methods for health services research
3. Epidemiologic research of physical activity and aging
1. Fibrinolysis factors (uPA etc.) and adhesion factors (CD44 variant

Community Healthcare
Education and ResearchCenteretc.) related to the breast cancer invasion and the metastasis.
－

Associate
Professor

UMEDA Tomoko

2. MRI mapping for the intraductal area of breast cancer
3. Tumor infiltrating cells around of the breast cancer, related to the
trastuzumab after neoadjuvant chemotherapy

Research Administration
OfficeResearch Strategy
Promotion OfficeSpecialContract
Associate
Professor

1. Research for regulatory mechanism of smooth muscle contraction.
HAYAKAWA Koichi

2. Drug discovery research for GPCR.
3. Research for intellectual property management in university.

30

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月Contact for Admission Selection, etc.
Admissions Division, Entrance Examination Section
Shiga University of Medical Science
Seta Tukinowa-cho, Otsu City, Shiga 520-2192, Japan
TEL : +81-77-548-2071
E-mail: hqnyushi@belle.shiga-med.ac.jp
https://www.shiga-med.ac.jp/