国立病院機構岡山医療センター脳神経内科業績（2003 年 4 月より）
英語論文61) Tanaka T,Fukuma K, Abe S, Matsubara S, Motoyama R, Mizobuchi M, Yoshimura
H, Matsuki T, Manabe Y, Suzuki J, Ikeda S, Kamogawa N, Ishiyama H, Kobayashi K,
Shimotake A, Nishimura K, Onozuka D, Koga M, Toyoda K, Murayama S, Matsumoto
R, Takahashi R, Ikeda A, Ihara M
Antiseizure medications for post-stroke epilepsy: A real-world prospective cohort study
Brain Behav 2021; 11: e2330.

60) Fujiwara S, Manabe Y, Nakano Y, Omote Y, Yunoki T, Kono S, Narai H, Abe K
Two cases of probable Neuro-Behçet's disease with longitudinally extensive transversemyelitis
Case Rep Neurol 2020; 12: 13-17.

59) Kuribayashi T, Manabe Y, Fujiwara S, Omote Y, Narai H, Abe K
Combined hypertrophic pachymeningitis and cerebral venous thrombosis in a case ofgranulomatosis with polyangiitis
Case Rep Neurol 2019; 11: 252-255.
58) Ikeda K, Manabe Y, Fujiwara S, Omote Y, Narai H, Abe K
Campylobacter fetus meningitis and pyogenic spondylodiscitis in a healthy youngwomanCase Rep Neurol 2019; 11: 299-303.
57) Tanaka T, Yamagami H, Ihara M, Miyata T, Miyata S, Hamasaki T, Amano S,Fukuma K, Yamamoto H, Nakagawara J, Furui E, Uchiyama S, Hyun B, Yamamoto Y,Manabe Y, Ito Y, Fukunaga R, Abumiya T, Yasaka M, Kitagawa K, Toyoda K,Nagatsuka K
Association of CYP2C19 polymorphisms with clopidogrel reactivity and clinicaloutcomes in chronic ischemic stroke
Circ J 2019; 83: 1385-1393.

156) Tadokoro K, Morihara R, Ohta Y, Hishikawa N, Kawano S, Sasaki R, Matsumoto N,Nomura E, Nakano Y, Takahashi Y, Takemoto M, Yamashita T, Ueno S, Wakutani Y,Takao Y, Morimoto N, Kutoku Y, Sunada Y, Taomoto K, Manabe Y, Deguchi K, Higashi
Y, Inufusa H, You F, Yoshikawa T, von Greiffenclau MM, Abe K
Clinical benefits of antioxidative supplement Twendee X for mild cognitive impairment:a multicenter, randomized, double-blind, and placebo-controlled prospective
interventional study.
J Alzheimers Dis 2019; 7: 1063-1069.
55) Aoki J, Iguchi Y, Urabe T, Yamaguchi H, Toda K, Fujimoto S, Idomari K, Kaneko N,Iwanaga T, Terasaki T, Tanaka R, Yamamoto N, Tsujino A, Nomura K, Abe K, Uno M,Okada Y, Matsuoka H, Yamagata S, Yamamoto Y, Yonehara T, Inoue T, Yagita Y,Kimura K, on behalf of the ADS investigators
Acute aspirin plus cilostazol dual therapy for non-cardioembolic stroke patients within
48 h of symptom onset
J Am Heart Assoc 2019; 8: e012652.
54) Kitagawa K, Yamamoto Y, Arima H, Maeda T, Sunami N, Kanzawa T, Eguchi K,Kamiyama K, Minematsu K, Ueda S, Rakugi H, Ohya Y, Kohro T, Yonemoto K, Okada
Y, Higaki J, Tanahashi N, Kimura G, Umemura S, Matsumoto M, Shimamoto K, Ito S,Saruta T, Shimada K, for the Recurrent Stroke Prevention Clinical Outcome(RESPECT) Study Group
Effect of standard vs intensive blood pressure control on the risk of recurrent stroke: arandomized clinical trial and meta-analysis
JAMA Neurol 201953) Mitsumune S, Manabe Y, Yunoki T, Kono S, Aoyama K, Shinno Y, Narai H, Abe K
Autologous bone marrow transplant for polymyositis combined with myasthenia gravis
and aplastic anemia: a case report
Case Rep Neurol 2018; 10: 108-111.
52) Fukumoto K, Manabe Y, Fujiwara S, Omote Y, Narai H, Yamada H, Saito T, Abe K
Meningitis due to a combination of Streptococcus mitis and Neisseria subflava: a casereport
Case Res Neurol 2018; 10: 177-180.
251) Kawano T, Miyashita K, Takeuchi M, Nagakane Y, Yamamoto Y, Kamiyama K,Manabe Y, Todo K, Metoki N, Akaiwa Y, Toyoda K, Nagatsuka K
Blood biomarkers associated with neurological deterioration in patients with acutepenetrating artery territory infarction: a multicenter prospective observational study
Int J Stroke 2018; 13: 207-216.

50) Takahashi Y, Manabe Y, Nakano Y, Yunoki T, Kono S, Narai H, Furujo M, Abe Y
Parkinsonism in association with dehydropteridine reductase deficiency
Case Rep Neurol 2017; 9: 17-2149) Takahashi Y, Manabe Y, Morihara R, Narai H, Yamashita T, Abe K
Neuromyelitis optica spectrum disorder coinciding with spinocerebellar ataxia type 31
Case Res Neurol 2017; 9: 127-13048) Takahashi Y, Yamashita T, Morihara R, Nakano Y, Sato K, Takemoto M, Hishikawa
N, Ohta Y, Manabe Y, Abe K
Different characteristics of anterior and posterior branch atheromatous diseases with orwithout early neurologic deterioration
J Stroke Cerebrovasc Dis 2017; 26: 1314-1320.
47) Morihara R, Yamashita T, Deguchi K, Tsunoda K, Manabe Y, Takahashi Y, Yunoki T,Sato K, Nakano Y, Kono S, Ohta Y, Hishikawa N, Abe K
Successful delyed aortic surgery for a patient with ischemic stroke secondary to aortic
dissectionIntern Med 2017; 56: 2343-2346.
46) Takahashi Y, Manabe Y, Nakano Y, Yunoki T, Kono S, Narai H, Omori N, Abe K
Fulminant case of neuromyelitis optica spectrum disorder initiated with area postrema
symptoms
Neurol Clin Neurosci 2016; 4:121-3.
45) Morihara R, Kono S, Sato K, Hishikawa N, Ohta Y, Yamashita T, Deguchi K,
Manabe Y,Takao Y, Kashihara K, Inoue S, Kiriyama H, Abe K
Thrombolysis with low-dose tissue palsminogen activity 3-4.5 h after ischemic stroke in3

five hospital groups in JapanTransl Stroke Res 2016; 7:111-9.
44) Takeuchi M, Miyashita K, Nakagawa J, Toyoda K,Toda K, Metoki N, Suzuki R,Manabe Y, Akaiwa Y, Yamamoto Y, Nagatsuka K
Analysis of factors associated with progression and log-term outcomes of penetratingartery territory infarction: a retrospective study
J Stroke Cerebrovasc Dis 2016; 25:1952-9.

43) Manabe Y, Morihara R, Matsuzono K, Nakano Y, Takahashi Y, Narai H, Omori N,Abe K.
Estimation of the presence of small dense lipoprotein cholesterol on acute ischemicstroke
Neurol Int 2015; 7: 5973.
42) Nakano Y, Manabe Y, Hattori M, Takahashi Y, Narai H, Omori N, Takeyama T, AbeK
Serial magnetic resonance imaging and single-photon emission computed tomography
findings in a patient with heat stroke
Neurol Clin Neurosci 2015; 3:179-181.
41) Morihara R, Kono S, Sato K, Hishikawa N, Ohta Y, Yamashita T, Deguchi K,Manabe Y,Takao Y, Kashihara K, Inoue S, Kiriyama H, Abe K
Thrombolysis with low-dose tissue palsminogen activity 3-4.5 h after ischemic stroke infive hospital groups in Japan
Transl Stroke Res 2016 Jan 2740) Matsuzono K, Manabe Y, Takahashi Y, Narai H, Omori N, Abe K.
Combined ipsilateral oculomotor nerve palsy and contralateral downbeat nystagmus in acase of cerebral infarction
Case Rep Neurol 2014; 6:134-138.
39) Matsubara Y, Manabe Y, Hattori M, Nakano Y, Takahashi Y, Narai H, Ota K, Abe K.
Serial MR spectroscopy in hypertensive encephalopathy
J Neurol Sci 2014; 347: 393-395.
438) Nomura E, Suzuki A, Inoue I, Nakagawara J, Takahashi K, Takahashi T, Manabe Y,
Yokota C, Okada K, Nishihara T, Yamamoto Y, Noda K, Takahashi S, Ibayashi S,Yakagi M, Kitagawa K, Tanahashi N, Kuriyama M, Hirata K, Hosomi N, Minematsu K,
Kobayashi S, Matsumoto M; J-STARS-L Investigators.
Subsequent vascular events after ischemic stroke: the Japan Statin Treatment Against
Recurrent Stroke-Longitudinal
J Stroke Cerebrovasc Dis 2015; 24: 473-479.
37) Surov A, Kiratli H, Im SA, Manabe Y, O’Neill A, Shinagare AB, Spielmann RP.
Intramuscular leukemic relapse: clinical signs and imaging findings. A multicentricanalysis
Skeletal Radiol 2015; 44: 491-496.

36) Fujimoto S, Manabe Y, Fujii D, Kozai Y, Matsuzono K, Takahashi Y, Narai H,Omori N, Adachi K, Nanba E, Nishino I, Abe K
A novel mutation of the GAA gene in adult-onset Pompe disease lacking
disease-specific pathology
Intern Med 52: 2461-2464, 201335) Matsuzono K, Yoshiki T, Wakutani Y, Manabe Y, Yamashita T, Deguchi K, Ikeda Y,Abe K.
Synchronized Babinski and Chaddock signs preceded the MRI findings in a case ofrepetitive transient ischemic attack
Intern Med 52: 2127-2129, 201334) Kono S, Deguchi K, Morimoto N, Kurata T, Yamashita T, Ikeda Y, Narai H, ManabeY, Takao Y, Kawada S, Kashihara K, Takehisa Y, Inoue S, Kiriyama H, Abe K.
Intravenous thrombolysis with neuroprotective therapy by edaravone for ischemic
stroke patients older than 80 years of age
J Stroke Cerebrovasc 22; 1175-1183, 201333) Takahashi T, Harada M, Kikuno T, Ujihara M, Sadamitsu D, Manabe Y, Yasaka M,Takayama H, Kobori S, Araki E
The prevalence of the metabolic syndrome in stroke patients: a prospective multicenter5study in Japan
Acute Medicine & Surgery 1; 17-22, 201432) Naga Y, Kohriyama T, Origasa H, Minematsu K, Yokota C, Uchiyama S, Ibayashi S,Terayama Y, Takagi M, Kitagawa K, Nomura E, Hosomi N, Ohtsuki T, Yamawaki T,
Matsubara Y, Nakamura M, Yamasaki Y, Mori E, Fukushima M, Kobayashi S,Shinohara Y, Yamaguchi T, Matsumoto M, J-STARS investigators
Rationale, design, and baseline features of a randomized controlled trial to assess theeffects of statin for the secondary prevention of stroke: the Japan Statin Treatment
Against Recurrent Stroke (J-STARS)Int J Stroke 9; 232-239, 201431) Yokoyama S, Manabe Y, Fujii D, Ikeda-Sakai Y, Narai H, Omori N, Abe K.
Intravenous tissue plasminogen activator therapy for an acute ischemic stroke patientwith later diagnosed unilateral moyamoya syndrome
J Stroke Cerebrovasc Dis 22; 1190-1192, 201330) Ikeda-Sakai Y, Manabe Y, Fujii D, Kono S, Narai H, Omori N, Monma K, Nishino I,Abe K.
Novel mutations of the GNE gene in distal myopathy with rimmed vacuoles presenting
with very slow progression
Case Rep in Neurol 4: 120-125, 201229) Fujii D, Manabe Y, Takahasi Y, Narai H, Omori N, Kusunoki S, Abe K.
A case of Fisher-Bickerstaff syndrome overlapped by Guillan-Barré syndrome
Case Rep Neurol 4: 212-215, 201228) Ikeda Y, Ohta Y, Kobayashi H, Okamoto M, Takamatsu K, Ota T, Manabe Y,Okamoto K, Koizumi A, Abe K.
Clinical features of SCA36: a novel spinocerebellar ataxia with motor neuron
involvement (Asidan)
Neurology 79: 333-341, 201227) Manabe Y, Fujii D, Kono S, Sakai Y, Tanaka T, Narai H, Omori N, Imai Y, Abe K.
Systemic blood pressure profile correlates with cardiac 123I-MIBG uptake in patientswith Parkinson’s disease6

J Neurol Sci 307: 153-156, 201126) Makimoto G, Manabe Y, Yamakawa C, Fujii D, Ikeda-Sakai Y, Narai H, Omori N,Abe K
Two cases of possible neuro-Sweet disease with meningoencephalitis as the initialmanifestation
Neurol Int 4: e5, 201225) Kono S, Deguchi K, Morimoto N, Kurata T, Deguchi S, Yamashita T, Ikeda Y,Matsuura T, Narai H, Omori N, Manabe Y, Yunoki T, Takao Y, Kawata S, Kashihara K,Abe K
Tissue plasminogen activator thrombolytic therapy for acute ischemic stroke in 4
hospital groups on JapanJ Stroke Cerebrovasc Dis 22; 190-196, 201324) Kurata T, Kametaka S, Ohta Y, Morimoto N, Deguchi S, Deguchi K, Ikeda Y, Takao
Y, Ohta T, Manabe Y, Sato S, Abe K
PSP as distinguished from CBD, MSA-P and PD by clinical and imaging differences atan early stage
Intern Med 50: 2775-81, 201123) Abe K, Ikeda Y, Kurata T, Ohta Y, Manabe Y, Okamoto M, Takamatsu K, Ohta T,Takao Y, Shiro Y, Shoji M, Kamiya T, Kobayashi T, Koizumi A
Cognitive and affective impairments of a novel SCA/MND crossroad mutation Asidan
Eur J Neurol 19; 1070-1078, 201222) Kono S, Manabe Y, Tanaka T, Fujii D, Sakai Y, Narai H, Omori N, Ueda M, Ando Y,Abe K.
A case of familial amyloid polyneruopathy due to Phe33Val TTR with vitreousinvolvement as the initial manifestation
Intern Med 49:1213-1216, 201021) Fujii D, Manabe Y, Tanaka T, Kono S, Sakai Y, Narai H, Omori N, Furujyo M, AbeK
Scheie syndrome diagnosed after cerebral infarction
J Stroke Cerebrovasc Dis 21; 330-332, 2012720) Kono S, Manabe Y, Fujii D, Sakai Y, Narai H, Omori N, Kitamoto T, Abe K
Serial diffusion-weighted MRI and SPECT findings in a Creutzfeldt-Jakob disease
patient with V180I mutation
J Neurol Sci 301:100-103, 201119) Inoue H, Nozawa T, Hirai T, Goto S, Origasa H, Shimada K, Uchiyama S,Hirabayashi T, Koretsune Y, Ono S, Hasegawa T, Sasagawa Y, Kaneko Y, Ikeda Y,
J-TRACE Investigators
Sex-related differences in the risk factor profile and medications of patients with atrial
fibrillation recruited in J-TRACE
Circ J 74: 650-654, 201018) Shinohara Y, Katayama Y, Uchiyama S, Yamaguchi T, Handa S, Matsuoka K,Ohashi Y, Tanahashi N, Yamamoto H, Genka C, Kitagawa Y, Kusuoka H, Nishimaru K,Tsushima M, Koretsune Y, Sawada T, Hamada C; CSPS 2 group.
Cilostazol for prevention of secondary stroke (CSPS 2): an aspirin-cotrolled,
double-blind, randamised non-inferiority trial
Lancet Neurol 9: 959-968, 201017) Manabe Y, Kono S, Tanaka T, Narai H, Omori N
High blood pressure in acute ischemic stroke and clinical outcome
Neurology International 1: e1, 200916) Ono Y, Manabe Y, Nishimura H, Kono S, Narai H, Omori N, Nanba Y, Abe K
Unusual progression of herpes simplex encephalitis with basal ganglia and extensive
white matter involvement
Neurology International 1: e9, 200915) Kono S, Manabe Y, Tanaka T, Fujii D, Sakai Y, Narai H, Omori N, Abe K
A case of Fahr’s disease presenting as chorea succesfully treated by the use ofquetiapine
Clinical Medicine: Case Reports 2: 1-3, 200914) Shinohara Y, Nishimaru K, for the S-ACCESS study group
Sarpogrelate versus aspirin in secondary prevention of cerebral infarction: differential
8efficacy in diabetes? Subgroup analysis from S-ACCESS
Stroke 40: 2862-2865, 200913) Omori N, Narai H, Tanaka T, Tanaka S, Yamadori I, Ichimura K, Yoshino T, Abe K,Manabe Y.
Epstein-Barr virus-associated T/NK cell-type central nervous system lymphoma which
manifested as a post-transplantation lymphoproliferative disorder in a renal transplant
recipientJ Neurooncol 87: 189-191, 200812) Omori N, Takada E, Narai H, Tanaka T, Abe K, Manabe Y
Spontaneous cervical epidural hematoma treated by the combination of surgicalevacuation and steroid therapy
Intern Med 47: 437-440, 2008
11) Fujita K, Tanaka T, Kono S, Narai H, Omori N, Manabe Y, Abe K
Urinary retention secondary tu Listeria meningitis
Intern Med 47: 1129-1131, 2008
10) Kurata T, Hayashi T, Murakami T, Miyazaki K, Morimoto N, Ohta Y, Takehisa Y,Nagai M, Kawarabayashi T, Takao Y, Ohta T, Harigaya Y, Manabe Y, Kamiya T, Shoji
M, Abe K
Differentiation of PA from early PSP with different patterns of symptoms and CBF
reduction
Neurol Res 30: 860-867, 20089) Shinohara Y, Nishimaru K, Sawada T, Terashi A, Handa S, Hirai S, Hayashi K, Tohgi
H, Fukuuchi Y, Uchiyama S, Yamaguchi T, Kobayashi S, Kondo K, Otomo E, Gotoh F,
for the S-ACCESS Study Group
Sarpogrelate-Aspirin comparative clinical study for efficacy and safety in secondary
prevention of cerebralinfarction (S=ACCESS)
Stroke 29: 1827-1833, 2008
8) Manabe Y, Hamakawa Y, Sunami K, Ohta Y, Omori N, Abe K.
Granurocytic sarcoma with orbit, cauda equine, muscle and peripheral nerve extension
but without bone marrow involvement.
9Intern Med 46: 633-635, 2007
7) Omori N, Takeuchi K, Tanaka T, Narai H, Kitagawa T, Abe K, Manabe Y
Efficacy of combined hyperbaric oxygenation therapy in a case of pyogenic
spondylodiscitis accompanied by an epidural and pelvic intramuscular gaseous abscessand encephalomeningitis
Eur J Neurol 15: e19-20, 20086) Ono Y, Manabe Y, Sakai K, Hayashi Y, Abe K.
Clonic perseveration in the subacute stage of Japanese encephalitis.
J Neurol Sci 251: 107-109, 2006.
5) Ono Y, Manabe Y, Hamakawa Y, Omori N, Abe K.
A case of steroid-responsive encephalitis lethargica syndrome with malignant catatonia.
Intern Med 46: 307-310, 2007
4) Ono Y, Manabe Y, Hamakawa Y, Murakami T, Omori N, Hayashi Y, Abe K.
Lacalized lesions on MRI in a case of hypertensive brainstem encephalopathy. Intern
Med 44: 1002-1005, 2005.
3) Murakami T, Ono Y, Akagi N, Oshima E, Hamakawa Y, Omori N, Shoji M, Hayashi
Y, Abe K, Manabe Y.
A case of superior cerebellar artery syndrome with contralateral hearing loss at onset.
J Neurol Neurosurg Psychiatry 76: 63-66, 2005.
2) Manabe Y, Anrather J, Kawano T, Niwa K, Zhou P, Ross E, Iadecola C,Prostanoid, not reactive oxygen species, mediate COX-2-dependent neurotoxicity.
Ann Neurol 25: 668-675, 2004.
1) Ayukawa R, Fujimoto H, Ayabe M, Shoji H, Matsui R, Iwata Y, Fukuda H, Ochi K,Noda K, Ono Y, Sakai K, Yakehisa Y, Yasui K,
An unexpected outback of Japanese encephalitis in the Chugoku district of Japan, 2002.
Jpn J Infect Dis 57: 63-66, 2004.

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