Schedule of Accreditation
issued byUnited Kingdom Accreditation Service
2 Pine Trees, Chertsey Lane, Staines-upon-Thames, TW18 3HR, UK

Invitro Genetics Ltd, trading as CooperGenomics
Issue No: 0118993

Issue date: 02 March 2020

CooperGenomics Nottingham

Contact: Leoni Xanthopoulou

MediCity (Building D6)

Tel: +44 (0) 207 6911122 ext 226

Thane Road

E-Mail: Leoni.Xanthopoulou@coopergenomics.com

Nottingham

Website: www.coopergenomics.com

NG90 6BH

Accredited toISO 15189:2012

United Kingdom

Testing performed by the Organisation at the locations specified below
Locations covered by the organisation and their relevant activities
Laboratory locations:
Location details

CooperGenomics Nottingham
MediCity (Building D6)
Thane Road
Nottingham
NG90 6BH

ActivityLocation
code

Local contact
Leoni Xanthopoulou

Preimplantation Genetic TestingA

Local contact
Leoni Xanthopoulou

Preimplantation Genetic Testing

B

United Kingdom

CooperGenomics London
Translation & Innovation Hub (I-HUB)
80 Wood Lane
Shepherd's BushLondon
W12 0BZ
United Kingdom

Assessment Manager: GB

1 of 3

S c he dul e of Ac c re di ta ti on
issued byUnited Kingdom Accreditation Service
2 Pine Trees, Chertsey Lane, Staines-upon-Thames, TW18 3HR, UK

Invitro Genetics Ltd, trading as CooperGenomics
8993

Issue No: 011

Accredited toIssue date: 02 March 2020

ISO 15189:2012
Testing performed by the Organisation at the locations specified

DETAIL OF ACCREDITATION
Materials/Products tested

Type of test/Properties
measured/Range ofmeasurement

Standard specifications/Equipment/Techniques used

HUMAN BODY TISSUE AND
FLUIDS

Molecular and Cytogenetics
examination activities for thepurposes of clinical diagnosis:

Documented In-house Methods
and Manufacturer’s instructions foranalyser with specific reference to:Biopsy samples from IVF
generated embryos

Copy number assessment for
chromosome aneuploidy

Preimplantation Genetic Screening(PGT-A) using Illumina SurePlex(PicoPLEX® Single Cell WGA kit)
whole genome amplification (WGA)and VeriSeq™ NGS and:

Location
CodeA
B

Illumina MiSeq
SOP 59 (Location A);
Illumina NextSeq analyser
SOP 92: NGS for PGT-A and PGTSR;
SOP 009: Whole Genome
Amplification via SUREPLEX(Location B)
via CooperGenomicsSM
PGTaiSM Bioinformatics technology
including EmbryoDx pipeline
automation

Assessment Manager: GB

Page 2 of 3

S c he dul e of Ac c re di ta ti on
issued byUnited Kingdom Accreditation Service2 Pine Trees, Chertsey Lane, Staines-upon-Thames, TW18 3HR, UK

Invitro Genetics Ltd, trading as CooperGenomics
8993

Issue No: 011

Accredited toIssue date: 02 March 2020

ISO 15189:2012
Testing performed by the Organisation at the locations specified

Materials/Products tested

Biopsy samples from IVF
generated embryos

Type of test/Properties
measured/Range ofmeasurement

Standard specifications/
Equipment/Techniques used

Detection of unbalanced
structural chromosomal
abnormalities via copy numberanalysis

Preimplantation Genetic Testing for
Structural Rearrangements (PGTSR) using:
WGA of embryo DNA by thepolymerase chain reaction (ABI3130), followed by preparation(quantification using the Qubit) andthe analysis of WGA DNA forvariation of chromosome copy
number by NGS using Illumina
MiSeq (Location A);

And
Detection of chromosome
aneuploidy via copy numberanalysis.

Location
CodeA
B

Illumina SurePlex (PicoPLEX®
Single Cell WGA kit) WGA andVeriSeq™ NGS,
Illumina NextSeq
SOP 92: NGS for PGT-A and PGTSR;
SOP 009: Whole Genome
Amplification via SUREPLEX(Location B)
via CooperGenomicsSM
PGTaiSM Bioinformatics technology
including EmbryoDx pipeline
automation
Biopsy samples from IVF
generated embryos

Detection of monogenic(single gene) defects

Preimplantation Genetic Testing(PGT-M) using karyomapping,nested PCR and Sanger
sequencing using Applied
Biosystems ABI 3130 Genetic
analyser; Illumina iScan Array
Scanning System
SOPs: SOP 070; 071; 072; 073;
015

BEND

Assessment Manager: GB

Page 3 of 3