Multiscale Brain/
Molecular and Cellular Cognition Society Asia

Constructive understanding of multiscale dynamism of brain and itsdisorders
Date: June 27-28, 2022
Venue: Ito Hall, Tokyo University

Organizers
Satoshi Kida (Tokyo University)
Yasunori Hayashi (Kyoto University)
SupportMEXT Grant-in-Aid for Scientific Research on Innovative Areas“Constructive understanding of multi-scale dynamism ofneuropsychiatric disorders”
SECOM Science and Technology Foundation
The Uehara Memorial Foundation
The NOVARTIS Foundation (Japan) for the Promotion of ScienceContact
Satoshi Kida: akida@g.ecc.u-tokyo.ac.jp
Yasunori Hayashi: yhayashi-tky@umin.ac.jp
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Access to Ito Hall, Tokyo University
From Narita or Haneda Airport to Tokyo

AirportTrain lines and major destinations in downtown Tokyo
JR Line: Narita Express to Tokyo, Shinagawa or Shinjuku Stations

Narita Airport

Keisei/Hokuso Sky Access Line: Skyliner to Nippori or Ueno
StationsHaneda Airport Keikyu Airport Line to Shinagawa Station
Do not take a taxi. It is too far away and can cost >US$200.
After arriving downtown Tokyo, please change to local line (JR or subway) to reachyour hotel.
Venue
Ito Hall is located on Hongo Campus of Tokyo University.
7-3-1, Hongo, Bunkyou-ku, Tokyo 113-0033+81-3-5841-0779 (international) or 03-5841-0779 (within Japan)(for GPS: 35.710N, 139.760E)
Hongo-sanchome Station (Marunouchi and Oedo Lines) is the closest station.

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For simplicity, not all stations are listed.

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Symposium Schedule
June 27, 2022
9:00–9:10

Opening Remarks – Chair of Multiscale Brain
Dr. Akiko Hayashi-Takagi (RIKEN CBS, Japan)

9:10–9:15

Opening Remarks – MCCS Asia
Dr. Satoshi Kida (Univ Tokyo, Japan)<Session 1> Chairman; Dr. Satoshi Kida (Univ Tokyo, Japan)
Sponsored by SECOM
9:15–9:40
Dr. Alicia Che (Yale Univ, USA)
Role of GABAergic interneurons in mediating early life experiences andimplications in psychiatric illnesses
9:40–10:05
Dr. Yasunori Hayashi (Kyoto Univ, Japan)
Online- and offline-LTP underlying long-term fear memory
10:05–10:30
Dr. Satoshi Kida (Univ Tokyo, Japan)
Potential roles of cAMP signaling pathway in PTSD
10:30–10:45<Session 2>

Coffee Break
Chairman; Dr. Tadafumi Kato (Juntendo Univ, Japan)

10:45–11:10
Dr. Gustavo Turecki (McGill Univ, Canada)
The depressed brain at single-cell resolution
11:10–11:35
Dr. Jelena Radulovic (Albert Einstein Med Coll, USA)
Primary cilia control the formation of lasting memories
11:35–12:00
Dr. Tadafumi Kato (Juntendo Univ, Japan)
Possible roles of paraventricular thalamic nucleus in bipolar disorder
12:00–13:00<Session 3>

Lunch Break
Chairman; Dr. Tomoyuki Furuyashiki (Kobe Univ, Japan)

13:00–13:25
Dr. Kanzo Suzuki (Vanderbilt, USA)
Synaptic mechanisms underlying rapid antidepressant action
13:25–13:50
Dr. Anatol Kreitzer (UCSF, USA)
Modulation of dopamine signaling by internal needs
13:50–14:15
Dr. Weidong Li (Shanghai Jiao Tong Univ, China)
Desipramine rescues memory deficits in mouse model of Kabuki syndrome
14:15–14:25

Coffee Break4

<Session 4>

Chairman; Dr. Ted Abel (Univ Iowa, USA)

14:25–14:50
Dr. Takanobu Nakazawa (Tokyo Univ. Agri. Japan)
Modelling psychiatric disorders with patient iPSC-derived neurons andmouse disease models
14:50–15:15
Dr. Zhihua Gao (Zhejiang Univ, China)
Oxytoxin and emotional control
15:15–15:40
Dr. Akiko Hayashi (RIKEN CBS, Japan)
Multi-scale synaptic analysis for schizophrenia
15:40–15:50<Session 5>

Coffee BreakChairman; Dr. Thomas McHugh (RIKEN CBS, Japan)

15:50–16:15
Dr. Mazen Kheirbek (UCSF, USA)
Representing rewarding and aversive experiences in hippocampal circuits
16:15–16:40
Dr. Juan Song (Univ North Carolina, USA)
Hypothalamic modulation of adult hippocampal neurogenesis and its
functional implication
16:40–17:05
Dr. Ted Abel (Univ Iowa, USA)
Endoplasmic reticulum chaperone genes encode effectors of long-termmemory<Poster Session>
17:05–19:00

With Snacks

5June 28, 2022
9:00–9:05

Dr. Satoshi Kida
General Information<Session 6> Chairman; Dr. Akiko Hayashi-Takagi (RIKEN CBS, Japan)
9:05–9:30
Dr. Gemma Modinos (King's Coll London, UK)
Translational approaches to the role of GABAergic dysfunction invulnerability for psychosis
9:30–9:55
Dr. Shusaku Uchida (Kyoto Univ, Japan)
Constructive understanding of the mechanisms underlying psychosocial
stress-induced behavioral heterogeneity
9:55–10:20
Dr. Tomoyuki Furuyashiki (Kobe Univ, Japan)
Inflammatory mechanisms of stress and depression
10:20–10:35<Session 7>

Coffee Break
Chairman; Dr. Josh Johansen (RIKEN CBS, Japan)

10:35–11:00
Dr. Matthew Girgenti (Yale Univ, USA)
Integrating single cell genomics to understand stress disorder
11:00–11:25
Dr. Atsushi Kasai (Osaka Univ, Japan)
Claustral ensemble for stress-induced anxiety responses
11:25–11:50
Dr. Takuya Sasaki (Tohoku Univ, Japan)
Hippocampal memory mechanisms underlie stress-induced psychiatricdisease11:50–13:00<Session 8>

Lunch Break
Chairman; Dr. Paul Frankland (Hosp Sick Kids, Canada)

13:00–13:25
Dr. Takashi Kitamura (Univ Texas, USA)
Role of Eph/Ephrin signals on anatomical and functional modules in medial
entorhinal cortex
13:25–13:50
Dr. Hyungju Park (Korea Brain Res Inst, Korea)
Regulation of learning and memory by astrocytic synapse pruning
13:50–14:15
Dr. Gisella Vetere (ESPCI Paris, France)
Decoding memory formation and stabilization in mice
14:15–14:25<Session 9>

Coffee Break
Chairman; Dr. Takashi Kitamura (Univ Texas, USA)6

14:25–14:50
Dr. Kobi Rosenblum (Univ Haifa, Israel)
Differential cell specific regulation of protein synthesis control different
neuronal and behavioral processes
14:50–15:15
Dr. Paul Frankland (Hosp Sick Kids, Canada)
The supramammilliary nucleus integrates environmental signals to modulate
mood and cognition via hippocampal neurogenesis
15:15–15:40
Dr. Yong-Seok Lee (Seoul Natl Univ, Korea)
Role of NAc-projecting infralimbic neurons in social recognition
15:40–15:50<Session 10>

Coffee Break
Chairman; Dr. Yasunori Hayashi (Kyoto Univ, Japan)

15:50–16:15
Dr. Eric Klann (New York Univ. USA)
Cell type-specific and local translation in memory
16:15–16:40
Dr. Takeshi Imai (Kyushu Univ, Japan)
Cortical development during adolescence
16:40–17:05
Dr. Justin Lee (Inst Basic Sci, Korea)
Reactive astrocytes as the cause of Alzheimer's disease
17:05–

Closing Remarks
Dr. Hiroyuki Nawa (Wakayama Med. Univ, Japan)

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