The 41st Annual Meeting of the Japanese Society
for Biomedical Mass Spectrometry

Program
September 15th (Thu) – 16th (Fri), 2016
Aichi Industry & Labor Center (WINC AICHI) 5F
4-4-38 Meieki, Nakamura‒ku, Nagoya, Aichi, 450-0002 JAPAN

Hiroshi Seno
President of the 41st Annual Meeting of
the Japanese Society for Biomedical Mass Spectrometry
Professor and Director, Department of Legal Medicine,
Aichi Medical University School of Medicine

1Time Schedule
September 15th (Thu)
8:45-

Registration

9:45- 9:50

Opening Remarks

9:50-11:30

Symposium 1

11:40-12:20

JSBMS Board Meeting

11:40-12:30

Luncheon Seminar 1

12:40-13:20

JSBMS General Meeting

13:30-14:30

Poster Presentation (Odd poster number)

14:40-16:20

Technology Forum

16:30-17:30

Special Lecture

18:00-

Post-Society Party

September 16th (Fri)8:45-

Registration

9:30-11:10

Symposium 2

11:20-12:20

Poster Presentation (Even poster number)

12:30-13:20

Luncheon Seminar 2

13:30-15:10

Symposium 3

15:10-15:15

Closing Remarks2

Program
September 15th (Thu)
8:45-

Registration

9:45-9:50

Opening Remarks

9:50-11:30

Symposium 1“Measurement of blood drug concentration using LC/MS”
Organizer: Hisao Oka (Kinjo Gakuin University)
Yasuhiro Maeda (Nagoya City University)

S1-1

Influence of the CYP2C19 gene polymorphism in the diazepam metabolism
Yasuhiro Maeda1, Yoko Nakajima2, Tetsuya Ito2, Kazunori Kimura1,3
1
Graduate School of Pharmaceutical Sciences, Nagoya City University
2
School of Medicine, Fujita Health University
3
Graduate School of Medical Sciences, Nagoya City University

S1-2

LC-MS/MS analysis of sedative drugs in blood samples for anesthesiology and medical crisis
management
Kochi Inoue1, Yoshito Fujita2
1
Ritsumeikan University College of Pharmaceutical Sciences
2
Aichi Medical University School of Medicine

S1-3

Usefulness of LC-MS in the study of crude drugs and Kampo medicine
Toshiaki Makino
Graduate School of Pharmaceutical Sciences, Nagoya City University

S1-4

New strategy to obtain deuterated internal standards for mass spectrometry: H-D exchange
reaction with heterogenous platinum group metal catalyst
Kaname Tsutsumiuchi1, Hisao Oka2
1
College of Bioscience and Biotechnology, Chubu University
2
Institute for Consumer Sciences and Human Life, Kinjo Gakuin University

11:40-12:20 JSBMS Board Meeting
11:40-12:30 Luncheon Seminar 1
LS1High resolution mass spectrometer with various chromatograph techniques
Masayuki Kubota
Thermo Fisher Scientific K.K. Japan

12:40-13:20 JSBMS General Meeting
13:30-14:30 Poster Presentation (Odd poster number)
P1

Performance of the MALDI-TOF Mass Spectrometry system in our hospital
Sakura Aso
Department of Clinical Laboratory, Niigata City General Hospital

P3-Introduction of using mass spectrometry- Bacterial identification by MALDI-TOF MS inclinical microbiology/Quantitative bioanalysis of drug by LC-MS/MS
Akihiko Aihara, Morio Honma, Tatsumi Kato, Akikazu Shiraishi, Hiroaki Umebayashi

3

JAPAN CLINICAL LABORATORIES
P5

Protein distribution analysis on mouse brain tissue by desorption electrospray ionization-ion
mobility-imaging mass spectrometry
Shoko Matsushista1,2, Thanai Paxton3, Noritaka Masaki1,2, Kohei Sato4, Eiji Sugiyama1,2, Futoshi
Sato3, Maki Terasaki3, Nobuyuki Mase4, Mitsutoshi Setou1,2
1Department of Cellular & Molecular Anatomy, Hamamatsu University School of Medicine
2
International Mass Imaging Center
3
Nihon Waters K.K.
4
Department of Applied Chemistry and Biochemical Engineering, Faculty of Engineering, Shizuoka
University

P7

Analysis of serotonin distribution in mouse intestinal tissue using MALDI imaging mass
spectrometry
Asako Saiki1,2,4, Aru Konno2, Shiro Takei2-4, Yoshihiro Takata1, Hirotaka Kaneda1, Youichi
Tsuchiya1, Mitsutoshi Setou2-4, Ikuko Yao2,4
1
Frontier Laboratories for Value Creation, SAPPORO HOLDINGS LTD.
2
Preeminent Medical Photonics Education & Research Center, Institute for Medical Photonics
Research, Hamamatsu University School of Medicine
3
Department of Cellular & Molecular Anatomy, Hamamatsu University School of Medicine
4International Mass Imaging Center

P9

Imaging of rat buccal mucosa by MALDI-IMSMariko Miyagi1-3, Ikuko Yao2,3, Mitsutoshi Setou1-3
1Department of Cellular & Molecular Anatomy, Hamamatsu Medical University School of Medicine
2Preeminent Medical Photonics Education & Research Center, Institute for Medical Photonics
Research, Hamamatsu University School of Medicine
3International Mass Imaging Center

P11

Measurement of acylcarnitine in urine and blood of a patient administration of sivelestat
sodiumYoko Maeda1, Yasuhiro Maeda1, Yasuko Togawa2, Kana Gotoh1, Yuji Hotta1, Tomoya Kataoka3,
Yoshihiro Kawade1, Norihisa Koyama2, Masanori Kouwaki2, Naruji Sugiyama4, Kazunori Kimura1
1
Graduate School of Pharmaceutical Sciences, Nagoya City University
2
Pediatrics Toyohashi Municipal Hospital3
Graduate School of Medical Sciences, Nagoya City University
4
Aichi Medical College for Physical and Occupational Therapy

P13

Measurement of the enzyme activities of patients with propionic academia using UPLC-MS/MS
Kana Gotoh1, Yasuhiro Maeda1, Yoko Nakajima2, Tetsuya Ito2, Go Tajima3, Yoko Maeda1, Yuji
Hotta1, Tomoya Kataoka4, Yoshihiro Kawade1, Kazunori Kimura1,4
1
Graduate School of Pharmaceutical Sciences, Nagoya City University
2
Department of Pediatrics, Fujita Health University
3
National Center for Child Health and Development
4
Graduate School of Medical Sciences, Nagoya City University

P15

Therapeutic drug monitoring of Zonisamide by liquid chromatography-tandem mass
spectrometry in veterinary clinics
Kazuo Azuma1, Syuntaro Komada1, Saya Kunihiro1, Kaori Araki1, Tomohiro Osaki1, Tomohiro
Imagawa1, Takeshi Tsuka1, Yusuke Murahata1, Yoshiharu Okamoto1, Norihiko Ito1,2
1
Tottori University, Faculty of Agriculture, Joint Department of Veterinary Medicine
2
Tokyo Medical University, Department of Opthamnology

P17

Development of a method for gas chromatography–mass spectrometry based metabolomics ofchildren urine extracted from disposable diaper
Yuko Ueda1, Jun Ueyama1, Yuka Sugiura1, Michihiro Kamijima2, Takaaki Kondo1, Isao Saito3,
Shinya Wakusawa1
1
Department of Pathophysiological Laboratory Sciences, Nagoya University Graduate School of
Medicine4

2

Department of Occupational and Environmental Health, Nagoya City University Graduate Schoolof Medical Sciences3
Food Safety and Quality Research Center, Tokai COOP Federation
P19

A metabolomics study on autism spectrum disorders by mass spectrometry
Qi Li, Chunhua Zhang
Department of Research & Development of MILS International, Japan

P21

Proteomic profiling of antigens in circulating immune complexes associated with livertransplantation
Nozomi Aibara1, Kaname Ohyama1, Masaaki Hidaka2, Naoya Kishikawa1, Naotaka Kuroda1
1
Graduate School of Biomedical Sciences, Nagasaki University
2
Department of Surgery, Nagasaki University Graduate School of Biomedical Sciences

P23

Development of next-generation quantitative proteomics “iMPAQT”
Susumu Yoshioka1,3, Masaki Matsumoto1, Keiichi Nakayama2
1
Division of Proteomics, Multi-scale Research Center for Prevention of Medical Science, Medical
Institute of Bioregulation, Kyushu University
2
Department of Molecular and Cellular Biology, Medical Institute of Bioregulation, Kyushu
University
3
Medical Solution Promotion Department, Business Management Center, LSI Medience Corporation

P25

Investigation of rapid metabolome analysis using nano-flow injection ESI/Q-TOFMS
Kentaro Taki1, Kei Zaitsu1,2, Yumi Hayashi1,2, Tomomi Asano1, Maiko Kusano1, Hitoshi
Tsuchihashi1, Akira Ishii1
1
Nagoya University Graduate School of Medicine
2
Institute for Advanced Research, Nagoya University

P27

Simultaneous analysis of equol and their metabolites in human plasma by liquid
chromatography-tandem mass spectrometry
Mizuki Kinoshita1, Kaori Hosoda1, Aki Obara1, Hiromi Shibasaki2, Akitomo Yokokawa2, Kazuo
Ishii1
1
Kyorin University Faculty of Health Sciences
2
Tokyo University of Pharmacy and Life Sciences School of Pharmacy

P29

Highly sensitive determination of 6β-hydroxycortisol and cortisol in human plasma by LCMS/MS
Ryohei Hirano, Hiromi Shibasaki, Akitomo Yokokawa, Takashi Furuta
Tokyo University of Pharmacy and Life Sciences, School of Pharmacy

P31

Simultaneous measurement of estrogens and clinical applications using the LC-MS/MS
Yui Miyabayashi1, Mamoru Satoh2, Masaki Takiwaki2, Motoi Nishimura1, Kazuyuki Matsushita1,
Fumio Nomura2
1
Department of Molecular Diagnosis, Graduate School of Medicine, Chiba University
2
Division of Clinical Mass Spectrometry, Chiba University Hospital

P33

Long-term and high concentration dopamine exposure enhances the glial endocannabinoid
signaling
Hiroshi Ochi, Yukari Hirata, Makoto Hamajima, Ichiro Isobe
Department of Legal Medicine, Fujita Health University School of Medicine

P35

Detection of testosterone esters in Dried Blood Spot (DBS) on sports doping testing
Asami Miyamoto1, Sho Shiomura1, Masato Okano1, Michiko Dohi2, Shinji Kageyama1
1Anti-Doping Laboratory, LSI Medience Corporation
2
Medical Centre, Japan Institute of Sports Sciences

P37

Deuteration of atropine by H-D exchange reaction with Pt/C-D2O-H2 system
Akihiro Miura1, Yuji Yokoyama1, Kaname Tsutsumiuchi1, Hisao Oka2
1
College of Bioscience and Biotechnology, Chubu University

5

2

Institute for Consumer Sciences and Human Life

P39

Evaluation of a preparation method that can be applied to both LC-MS/MS and GC-MS forthe screening of postmortem specimens
Brian Waters1, Kenji Hara1, Natsuki Ikematsu1, Tomoko Tokuyasu1, Hiroshi Fujii1,2, Mio Takayama1,
Aya Matsusue1, Masayuki Kashiwagi1, Shin-ichi Kubo1
1
Fukuoka University, Faculty of Medicine, Department of Forensic Medicine
2
Narcotics Control Department, Kyushu Regional Bureau of Health and Welfare, Ministry of Health,Labour and Welfare, Fukuoka, Japan

P41

Analysis of Plant Alkaloids Through Accurate Mass Screening and Next Generation
Informatics Platform
Maki Terasaki1, Jeff Goshawk2, Michelle Wood2
1
Nihon Waters K. K.
2
Waters Corporation

P43

Efforts of building the drug screening system for drug statistical survey in forensic autopsy (2)– The quality management in drug analysis with blind tests –Chizuko Sasaki1, Hiroko Abe2, Kyoko Maebashi3, Hirotaro Iwase2, Kimiharu Iwadate3, Fumiko
Satoh1
1
Department of Legal Medicine, Kitasato University School of Medicine
2
Department of Legal Medicine, Graduate School of Medicine, Chiba University
3
Department of Forensic Medicine, The Jikei University School of Medicine

P45

High resolution and high precision analysis of barbiturates in human body fluids using amonolithic C18 gel-packed spin tip and UPLC-Q-Tof-MS
Xiao-Pen Lee1, Chika Hasegawa2, Takeshi Kumazawa1,3, Shota Miyazaki4, Yukiko Shouji1, Masaya
Fujishiro1, Akemi Marumo1, Keizo Sato1
1
Department of Legal Medicine, Showa University School of Medicine
2
Department of Legal Medicine, Toho University School of Medicine
3
Seirei Christopher University School of Nursing
4
GL Sciences Inc.

P47

Xanthine Oxidoreductase Activity assay using Liquid Chromatography-Mass Spectrometry
Takayo Murase, Atsushi Miyachi, Takashi Nakamura
Mie Research Laboratories, Sanwa Kagaku Kenkyusyo Co., Ltd.

14:40-16:20 Technology Forum
Chairperson: Yoshitomo Ikai (Aichi Prefectural Institute of Public Health): Fumio Kondo (Aichi Medical University)
TF1

Elements for Metabolomics to process, organize and interpret large scale metabolomics
experiments datasets
Shigetoshi Yoshikawa
INFOCOM CORPORATION

TF2

X500R QTOF system: New high resolution MS system
Ushio Takeda
SCIEX

TF3

Introduction of triple quadrupole mass spectrometer
Jun Watanabe
Shimadzu Corporation

TF4

Introduction of High resolution GC-MS/MS system equipped with Orbitrap
Masayuki Kubota
Thermo Fisher Scientific K.K. Japan

6

TF5

Exosome purification columns
Nozomi Iwanami1, Koji Ueda2
1
GL Sciences Inc.
2
Project for Realization of Personalized Cancer Medicine, Genome Center, Japanese Foundation forCancer Research

TF6

Certified Reference Materials for reliability of analysis
Taisuke Ueda
Sigma Aldrich Japan G.K.

TF7

UniSpray ion source, an alternative to ESI, APCI and APPI
Maki Terasaki
Nihon Waters K. K.

TF8High-sensitivity, high-throughput quantitation of catecholamines and metabolites in plasma by
LC/MS/MS analysis
Maiko Kaneko
Biotage Japan, Ltd.

16:30-17:30 Special Lecture
SL

Chairperson: Hiroshi Seno (Aichi Medical University)
Metabolomics and its Application to Medical and Food Sciences
Masaru Tomita
Institute for Advanced Biosciences, Keio University

18:00-

Post-conference Party
Nagoya Marriott Associa Hotel - Azalea - (16F)

September 16th (Fri)8:45-

Registration

9:30-11:10

Symposium 2“Mass spectrometry in the diagnosis of infectious diseases -Current
status and issues-”
Organizer: Hiroshige Mikamo (Aichi Medical University)
Kiyofumi Okusu (Tokyo Medical University)

S2-1

Current status of MALDI-TOF MS in Aichi Medical University Hospital Microbiological
Laboratory
Yuka Yamagishi1,2, Atsuko Yamada2, Rieko Yamashita2, Tomoko Ohno2, Yuzuka Kawamoto2,
Narimi Miyazaki2, Daisuke Sakanashi2, Isao Koita2, Setsuo Miyajima2, Hiroyuki Suematsu2,
Hiroshige Mikamo1,2
1
Department of Clinical Infectious Diseases, Aichi Medical University Hospital2
Department of Infection Control and Prevention, Aichi Medical University Hospital

S2-2

The operation and the issues of bacterial identification using the mass spectrometry at Shinshu
University Hospital
Go Matsumoto1, Takehisa Matsumoto2, Eriko Kasuga3, Tatsuya Natori3, Shinitiro Kanai1, Takayuki
Honda1,3
1
Infection control team, Shinshu University Hospital2
Department of Laboratory Sciences, Gunma University Graduate School of Health Sciences3
Department of Laboratory Medicine, Shinshu University School of Medicine

7

S2-3

A few tricks on running microbiology laboratory using VITEK MS and our future challenges
Tomohisa Watari
Department of Medical Laboratory and Blood Center, Asahikawa Medical University Hospital

S2-4

The challenges in introduction of MALDI-TOF MS (VITEK MS) for clinical microbiology
laboratory at Kyusyu University Hospital
Makiko Kiyosuke
Clinical Chemistry and Laboratory Medicine, Kyushu University

11:20-12:20 Poster Presentation (Even poster number)
P2

Examination of the bacteria identification rate improvement by the MALDI-TOF MS (Matrix·Sandwich Method)
Takenori Yamashita
Yodogawa Christian Hospital Department of Clinical Laboratory bacteria laboratory

P4

Imaging Mass Spectrometry Analysis of ganglioside GM1 molecular species in the dentate
gyrus of Alzheimer’s disease patients
Wakako Hirano-Sakamaki1, Eiji Sugiyama2, Takahiro Hayasaka3, Rivka Ravid4, Mitsutoshi Setou2,
Takao Taki5
1
Department of Medical Innovations, New Drug Research Division, Otsuka Pharmaceutical Co., Ltd.
2
Department of Cell Biology and Anatomy, Hamamatsu University School of Medicine
3
Faculty of Health Sciences, Hokkaido University
4
Brain Bank Consultants, The Netherlands
5
Tokushima University

P6

Application of mass spectrometry imaging for the screening of novel factors involved inregulation of AMPK activity in diabetic kidney disease
Satoshi Miyamoto1-4, Cheng-Chih Hsu5, Gregory Hamm6, Manjula Darshi2,3, Jonathan Stauber6,
Pieter C. Dorrestein2,5, Kenichi Shikata1, Kumar Sharma2-4
1
Center for Innovative Clinical Medicine, Okayama University Hospital2
Institute of Metabolomic Medicine, University of California San Diego
3
Center for Renal Translational Medicine, University of California San Diego
4
Veterans Affairs San Diego Healthcare System
5
Therapeutic Discovery Mass Spectrometry Center, University of California San Diego
6
ImaBiotech, MS Imaging Department, Lille, France

P8

Cystathionine β-synthase is required for maintaining levels of glutathione hydropersulfide, anovel antioxidant molecule in the murine lens
Akiko Kubo1, Takafumi Yoshioka1,2, Shinichi Goto1, Isao Ishii3, Takako Hishiki1, Takehiro
Yamamoto1, Naoharu Takano1, Takao Hoshino1, Takashi Nakamura1, Akitoshi Yoshida2, Mayumi
Kajimura1, Makoto Suematsu1
1
Keio University School of Medicine
2
Asahikawa Medical University
3
Showa Pharmaceutical University

P10

Development of new non-derivatization method for quantitative analysis of serum
acylcarnitines using LC-MS/MS and comparison with existing method of abbreviated analysis
Hironori Kobayashi1, Kenji Yamada1, Ryosuke Bo1, Yuki Hasegawa1, Seiji Yamaguchi1, Naoko
Ohyama2, Kazuhiro Takeuchi2, Tomoyoshi Shiroshita2, Akira Ideno2
1
Department of Pediatrics, Shimane University, Faculty of Medicine
2
SEKISUI MEDICAL CO., LTD.

P12

The diagnosis of Japanese patients with HMG-CoA synthase deficiency by urinary organic
acids analysis using GC/MS
Yuki Omura-Hasegawa, Kenji Yamada, Hironori Kobayashi, Seiji Yamaguchi
Department of Pediatrics, Shimane University School of Medicine

8

P14

Measurement of reverse T3 by LC-MS/MS and development of early diagnosis for MCT8
deficiency
Hideyuki Iwayama1, Masaru Nakano2, Minoru Fukayama1, Akihisa Okumura1
1
Aichi Medical University School of Medicine
2
Nagoya City University Graduate School of Medical Sciences

P16

Study on clinical significance of urinary high methionine by GC/MS analysis
Mingji Jin, Qi Li, Zonghai Ruan, Chunhua Zhang
Department of Research & Development of MILS International

P18

Study on clinical significance of urinary cyclic citrulline in CTLN2 patient by GC/MS
Chunhua Zhang, Zonghai Ruan, Qi Li, Mingji Jin, Ning Zhao
Department of Research & Development of MILS International

P20

Diagnostic method for X-linked adrenoleukodystrophy using liquid chromatography-tandem
mass spectrometry
Ryuichi Mashima1, Misa Tanaka1, Eri Sakai1, Tadayuki Kumagai1, Motomichi Kosuga1-3, Torayuki
Okuyama1,2
1
Department of Clinical Laboratory Medicine, National Center for Child Health and Development
2
Center for Lysosomal Storage Disease, National Center for Child Health and Development
3
Division of Medical Genetics, National Center for Child Health and Development

P22

Elucidation of the anticancer drug resistant mechanisms using a global lipid analysis
Takanori Hiraide1,2, Takanori Sakaguchi1, Satoru Furuhashi1,2, Ryota Kiuchi1,2, Makoto Takeda1,2,
Yasushi Shibasaki1,2, Yoshifumi Morita1,2, Eiji Sugiyama2,3, Hiroyuki Konno1, Mitsutoshi Setou2,31Second Department of Surgery, Hamamatsu University School of Medicine
2
International Mass Imaging Center, Hamamatsu University School of Medicine
3
Department of Cellular & Molecular Anatomy, Hamamatsu University School of Medicine

P24

Quantitative and quantitative analysis of glucosylated lipids by HILIC-ESI-MS/MS and clinicalapplications
Kazuki Nakajima1,3, Hisako Akiyama1, Emi Ito1, Kazuhisa Iwabuchi2, Yukio Yuzawa3, Yoshio
Hirabayashi1
1
RIKEN, BSI
2
Juntendo University School of Medicine
3
Fujita Health University

P26

Development of a nano LC/MS/MS method for simultaneous analysis of bile acids and its
application to bile-profiling of rat liver
Tomomi Asano1,2, Kei Zaitsu1, Kentaro Taki1, Maiko Kusano1, Kazuya Kitamori2, Hisao Naito3,
Tamie Nasu4, Hitoshi Tsuchihashi1, Akira Ishii1
1
Nagoya University Graduate School of Medicine
2College of Human Life and Environment, Kinjo Gakuin University
3
Fujita Health University School of Medicine
4College of Life and Health Sciences, Chubu University

P28

Analyses of fatty acids in used culture media for human embryos by LC/MS
Shu-Ping Hui1, Akiko Yagi2, Satoshi Miyanaga1, Rojeet Shrestha1, Seiji Takeda1, Hirobumi Kamiya2,
Hitoshi Chiba1
1Faculty of Heath Science, Hokkaido University
2
Kamiya Ladies Clinic

P30

Sphingomyelin profile of Abcd1 knockout mouse brain
Kotaro Hama1, Yuko Fujiwara1, Masashi Morita2, Tsuneo Imanaka2, Nobuyuki Shimozawa3,
Kazuaki Yokoyama1
1
Teikyo University Faculty of Pharmaceutical Sciences
2
University of Toyama Graduate School of Medicine & Pharmaceutical Sciences
3
Gifu University Life Science Research Center

9

P32

Evaluation of the physiologic change of serum HODE using LC/MS/MS
Akiko Nobata1, Yoshitomo Notsu1, Seiji Mishima1, Atsushi Nagai1, Toru Nabika2
1
Department of Laboratory Medicine, Shimane University, Faculty of Medicine
2
Department of Functional Pathology, Shimane University, Faculty of Medicine

P34

Analysis of GAG in human l lumbar ligamentum flavum
Harumi Osago1, Michihaya Kono2, Mikiko Miura1, Yoshifumi Hamasaki1, Nobumasa Hara1,
Mineyoshi Hiyoshi1, Yuji Uchio2, Mikako Tsuchiya1
1
Department of Biochemistry, Shimane University, Faculty of Medicine
2
Department of Orthopedic Surgery, Shimane University, Faculty of Medicine

P36

Development of relative quantitative analysis method for oligosaccharide based upontransglycosylation reaction by mutant enzyme Endo-M-N175Q
Jun Zhe Min, Hashimoto Ryugo, Kenichiro Todoroki, Hajime Mizuno, Toshimasa Toyooka
School of Pharmaceutical Sciences, University of Shizuoka

P38

Application of imipramine metabolite for functional material
Hideki Hayashi1,2, Junpei Kuno3, Taiki Naruo3, Hiroki Hirota3, Tadashi Ogawa2, Hideki Hattori2,
Hiroshi Seno2, Yukio Onouchi3, Yuzo Ishigaki1
1
Nagoya Municipal Industrial Research Institute2
Aichi Medical University School of Medicine
3
Faculty of Engineering, Aichi Institute of Technology

P40

Analysis of metabolites of biperiden by MALDI-QTOF-mass spectrometry
Kayoko Minakata1, Masako Suzuki2, Hideki Nozawa1, Itaru Yamagishi1, Kunio Gonmori1, Koutaro
Hasegawa1, Osamu Suzuki1, Kanako Watanabe1
1Department of Legal Medicine, Hamamatsu University School of Medicine
2
Research Equipment Center, Hamamatsu University School of Medicine

P42

Efforts of building the drug screening system for drug statistical survey in forensic autopsy (1)– Introduction of Drug Screening Method Sharing Project –Kyoko Maebashi1, Hiroko Abe2, Chizuko Sasaki3, Hirotaro Iwase2, Fumiko Satoh3, Kimiharu
Iwadate1
1
Department of Forensic Medicine, The Jikei University School of Medicine
2
Department of Legal Medicine, Graduate School of Medicine, Chiba University
3
Department of Legal Medicine, Kitasato University School of Medicine

P44

Efforts of building the drug screening system for drug statistical survey in forensic autopsy (3)– Introduction of Drug Screening Report System –Hiroko Abe1, Shinya Nakashima2, Yuji Ito3, Kyoko Maebashi4, Isora Tatematsu4, Chizuko Sasaki5,
Kimiharu Iwadate4, Fumiko Satoh5, Hirotaro Iwase1
1
Department of Legal Medicine, Graduate School of Medicine, Chiba University
2
Science Software Inc.
3
Nihon Techno Kaihatsu Co., Ltd.
4
Department of Forensic Medicine, The Jikei University School of Medicine
5
Department of Legal Medicine, Kitasato University School of Medicine

P46

Application of a new monolithic SPE spin tip and mass spectrometry for analysis of drugs inhuman blood
Chika Hasegawa1,3, Takeshi Kumazawa2,3, Xiao-Pen Lee3, Shota Miyazaki4, Keizo Sato3, Hiroshi
Seno5, Kunihiko Kurosaki1
1
Department of Legal Medicine, Toho University School of Medicine
2
Seirei Christopher University School of Nursing
3
Department of Legal Medicine, Showa University School of Medicine
4
GL Sciences Inc.
5
Department of Legal Medicine, Aichi University School of Medicine

1012:30-13:20 Luncheon Seminar 2LS2

Approach to Omics Research using LC/MS/MS
Jun Watanabe
Shimadzu Corporation

13:30-15:10 Symposium 3“Novel Development of Disease Lipoquality Research”
Organizer: Mitsutoshi Setou (Hamamatsu University School of Medicine)
Kazutaka Ikeda (RIKEN)
S3-1

Discovery of novel brain glycolipid involved in Parkinson’s disease by HILIC-MS/MS
Hisako Akiyama1, Kazuki Nakajima1, Yoshiyuki Itoh2, Tomoko Sayano1, Yasuko Nagatsuka1, Yoko
Ohashi1, Yoshiki Yamaguchi3, Peter Greimel4, Yoshio Hirabayashi1
1
Laboratory for Molecular Membrane Neuroscience, RIKEN Brain Science Institute2
JEOL Ltd.
3
Structural Glycobiology Team, Systems Glycobiology Research Group, RIKEN-Max Planck Joint
Research Center, Global Research Cluster, RIKEN
4
Lipid Biology Laboratory, RIKEN

S3-2

New insight into lipoquality research with non-target analysis
Kazutaka Ikeda1,2, Yuuya Senoo1, Makoto Arita1,3
1
RIKEN Center for Integrative Medical Sciences (IMS)2
AMED-PRIME
3
Graduate School of Pharmaceutical Sciences, Keio University

S3-3

Lipid analysis of spinal disease by matrix-assisted laser desorption/ionization imaging mass
spectrometry
Tomohiro Banno1,2, Hideyuki Arima1, Mitsuru Hanada1, Yukihiro Matsuyama1, Mitsutoshi Setou2,31
Department of Orthopaedic Surgery, Hamamatsu Medical University School of Medicine
2
Department of Cellular and Molecular Anatomy, Hamamatsu Medical University School of
Medicine
3
International Mass Imaging Center

S3-4

Imaging mass spectrometry for visualization of steroid hormones in tissues
Yuki Sugiura1, Shuichi Shimma1, Tatsuya Higashi2, Koshiro Nishimoto1
1
Department of Biochemistry, School of Medicine, Keio University
2
Department of Biotechnology, Graduate School of Engineering, Osaka University
3
Tokyo University of Science, Faculty of Pharmaceutical Sciences, Department of Pharmacy

15:10-15:15 Closing Remarks11