FOCUS ON:

Oncology Systems

Focused and committed
to helping you deliver

Excellence inOncology IV Therapy

Enhance Patient Safety

Improve Clinical Efficiency

Powerful medications used in cancer treatments are critical to patient care,but they also pose a safety risk to healthcare workers.
At ICU Medical, our focus is on delivering safe, efficient, and cost-effective
oncology systems that fit seamlessly into your workflows and help you
keep pharmacists and clinicians safe from hazardous drug exposure
from preparation to administration.

Maximize Profitability

Preparation with ChemoLock™
& ChemoClave™ CSTDs for
USP <800> Compliance
Complete Line of Diluents andContainers for Preparationof Oncology Admixtures

Helping you keep healthcare
Automated Compounding
and Remote Verification
with the Diana™
Workflow System

workers safe from hazardous
drug exposure and comply
with USP <800>
Enhance Safety

Only ICU Medical lets you
keep a closed system frombeginning to end*

Patient Administration
with ChemoLock andChemoClave CSTDs for
USP <800> Compliance

Complete IV-EHR
Interoperability withICU Medical MedNet™
Infusion Documentation
to Deliver Charge Capture
with ICU Medical MedNet* Plum 360 provides a closed system when using the PlumSet™
with Clave™ secondary port and a closed system transfer device

Plum 360™ Infusion
Pump with Unique Air
Management Technology>

Track preparation data with automated pharmacy
compounding and ensure accurate dosing with smart
pump programming infusion technology.

>

Maintain a closed system that enhances end-to-end
safety and helps to comply with USP <800>.

Improve Efficiency>

Simplify the compounding process with automatedcompounding with remote verification and ‘click to lock’
CSTD technology.

>

Improve nursing efficiency with infusion pumps featuring
unique air management and IV-EHR interoperability, alongwith easy-to-use luer-based CSTDs.

>

Reduce chair time by delivering two compatible
medications simultaneously at independent rates
through a single line.

Maximize Profitability>

Improve financial performance by maximizing
reimbursement with accurate infusion documentation andreducing chair time with concurrent medication delivery.

>

Minimize CSTD and IV set costs by reducing components
at each step.

In Pharmacy
We design our products to align with your existing workflows, helping you reduce medicationerrors and streamline the flow of data from pharmacy to nursing.
SafetyEfficiency

Profitability

Complete Line of Diluents and Containers
for Preparation 0f Oncology Admixtures
Complete Line of Diluents and Container Sizes
Empty Admixture Containers
DEHP-Free Containers Available

ChemoLock and ChemoClave
CSTDs for USP <800> Compliance
Reduce Exposure to Hazardous Drugs
Easy-to-Use Closed Systems
Save Costs with Multipacks and Speciality Kits
Maintain Sterility of Drug Vial

The Diana Compounding Workflow
System for Increased Efficiency
Remote Verification
Integrated CSTDs
Accuracy without the Use of Gravimetric Scales
Automated Ambulatory Cassette
Filling and Air Removal

In Nursing
We reduce steps while helping you improve safety, letting you
focus on your patients.
SafetyEfficiency

Profitability

ChemoLock and ChemoClave
CSTDs for USP <800> Compliance
Sets with Prebonded CSTDs
Cost-Effective CSTD Implementation
Easy-to-Use CSTDs

Full IV-EHR Interoperability
with ICU Medical MedNet
Smart Pump Programming
Automated Start/Stop Time Capture
Alarm Forwarding

Plum 360 Infusion Pump withUnique Air Management Technology
Reduce Air-in-Line Alarms
Automated Backpriming
Reliable Secondary Delivery
Data You Can TrustEnhance Medication Safetywith ICU Medical MedNet
Unmatched Drug Library ComplianceComprehensive Reports
Industry-Leading Cybersecurity
Deliver Medications as Ordered

ICU Medical offers two CSTD
solutions to meet your needs

Enhance safety with compounding and infusion
system technology that connects to your EHR
Maintain drug vial
sterility for up toICU Medical’s easy-to-use closed system transfer devices (CSTDs) and automated compounding workflow

7 Daysextension of your electronic health record (EHR), helping you reduce medication errors, increase patient1

system are designed to help you minimize exposure to hazardous drugs and comply with USP <800>. Oursmart infusion systems with ICU Medical MedNet safety software and full IV-EHR interoperability act as ansafety, and streamline the flow of data from pharmacy to administration.

Maximize safety and maintain a closed system frompreparation through administration with easy-to-use
USP <800> compliant CSTDs*>

The ChemoLock system’s locking mechanism eliminates unsafe
disconnects, helping you comply with USP <800> CSTD guidelines.

Track preparation data and enhance accuracy with IV workflowtechnology and automated pharmacy compounding thatconnects to your EHR>

Connecting the Diana compounding workflow system to your EHR lets
you maintain an accurate record of each preparation, ensuring greater
accuracy than manual compounding.

>

Automated compounding with Diana has been shown to provide
compounding accuracy of ±1% 2.

Ensure accurate dosing with smart pump programming
technology and maintain a closed system with air
management pump technology*

12

Microbial Ingress Study for ChemoLock™ Devices. Report of a study commissioned by ICU Medical Inc. and conducted by AAIPharma Services Corp.
Accuracy Evaluation of the Diana™ Compounding Workflow System, 2017.

* When using PlumSet™ with Clave secondary
port and a closed system transfer device.

>

ICU Medical MedNet IV safety software helps you eliminate potentiallycatastrophic dosing errors associated with manual programming, while
our proven Plum 360 infusion system helps you reach up to 98% drug
library compliance.

>

Plum 360 is the only infusion system to allow automated backpriming toremove air from the line without disconnection, helping you maintain aclosed system throughout drug delivery.

>

Plum 360 eliminates the risk for common secondary setup errors,
which have been shown to occur in 48% of secondary infusions.

Improve efficiency with innovative technologies
designed to complement the way you work today
ICU Medical’s oncology systems deliver everything you need to standardize your IV oncology workflow.
Our Diana drug compounding workflow system combines both automation and IV workflow technologies
with wireless pharmacist notification to let you remotely verify preparations on a handheld tablet. You
can streamline the flow of medications and data from pharmacy to administration with smart pumpprogramming technology and IV pumps with complete IV-EHR interoperability.

Speed up the compounding process with remote pharmacist
verifications and easy-to-use ‘click to lock’ CSTD technology>

With Diana, you can maximize compounding efficiencies and safety
by remotely verifying every mix without having to gown up andenter the cleanroom.

>

Prepare medications more safely and efficiently using ourChemoLock CSTD that snaps together with an audible click toensure a safe and secure connection.

Improve nursing efficiency with infusion systems featuringclosed air management and full IV-EHR interoperability>

Reduce the time it takes nurses to program pumps by up to 25%
with smart pump programming, freeing up nurses tospend more time caring for patients.

>

Eliminate manual steps traditionally required for EHR documentation
with infusion documentation.

>

Monitor alarms more efficiently and effectively with alarm forwarding.

Air-In-Line Alarms>

Over the course of three administration
cycles, the competitive pump registereda total of 21 air-in-line alarms while the1Plum 360 registered zero alarms.

Plum 360
Average0

Plum 360
Total0Competitor
Average4.2

Competitor
Total

21051015

Number of Alarms
1JW Beared, Zehra Madhany, Healther Witek. The Role of Infusion Pump Technology in Optimizing Efficiency in Cancer Care Delivery, 2017.

2025

Save timeby remotely reviewing
preparation photos
and data and verifying
the mix on a handheld
tablet display

Maximize profitability by improving reimbursements
and lowering product implementation costs
From preparation to administration, ICU Medical IV oncology technologies help you effectively andefficiently boost profitability. Our infusion systems become an extension of your EHR to help you
maximize revenue capture and eliminate lost charges through accurate documentation. Our uniquesecondary delivery technology lets you purchase fewer devices to administer the same amount ofmedications, while our lower cost CSTDs are included on pre-assembled sets with bonded components
to maximize safety and minimize set costs.

12%

Improve financial performance by maximizing reimbursementswith accurate infusion documentation and reducing chair time

Reduction in chair timeby concurrent medicationdelivery with Plum 360>

Increase revenue capture with accurate infusion documentationof start/stop times.

>

Purchase fewer devices and reduce operating expenses by delivering
compatible medications via secondary set with the unique concurrent
flow technology of the Plum 360.

>

Improve patient turnaround time by reducing air-in-line alarms withthe unique air management technology of the Plum 360.

Minimize CSTD and IV set costs by reducing components at each step>

Offset administration costs while preventing
accidental misuse and reducing set-up timewith CSTDs requiring no extra parts oradd-on components.

The ChemoClave system helps
you comply with USP <800>
and was shown to cost up to$307,000 less to implement
than competing systems.*

$500K
$450K

$435,473$400K$393,978

$350K
$300K
Cost

10%>

Reduce costs and packaging wastewith options to purchase multipack
CSTD components.

$507,287

Total Annual Costs Associated withImplementing Competing CSTDs1
Reduction in costwith multipacks>$239,020

$250K
$200K

$200,281

$150K
$100K
$50K
$0

* Component cost may vary slightly due to manufacturing price changes, contract pricing,
and/or volume discount pricing. Texium/SmartSite is marketed as a closed system, not a CSTD.
1Barnachea L, Lee T, Gitler J, Saria M. Cost Determination Study of Closed System Transfer Devices (CSTD). Presented at the California Society of Health System Pharmacists (CSHP), November 4, 2011.

PhaSeal

EquaShield

OnGuard

Texium/SmartSite

ChemoClaveA commitment to exceptional
ongoing technical support andclinical education
Our commitment to you doesn’t end with the purchase. We provide a dedicated support
organization with a wealth of knowledge, resources, and technical training opportunities
to help you maximize the value of your investment in ICU Medical products.
When you choose ICU Medical, you are choosing a true partner who will be with you
every step of the way, offering:> Best-in-class technical and clinical in-servicing> Dedicated field service engineers available> Personalized instructional materials© 2018 ICU Medical Inc.

|P19-3772-R1

For safe and proper use, refer to the Instructions for Use.

800.824.7890 | www.icumed.com