SAFETY DATA SHEETSDS No.5010-29014

Revised date

April 15, 2019

1/5 page

1. PRODUCT AND COMPANY IDENTIFICATIONPRODUCT NAME
： 10% Silver Nitrate-impregnated Silicagel
NAME OF SUPPLIER： GL Sciences Inc.
ADDRESS： 22-1 Nishishinjuku 6-chome Shinjuku-ku Tokyo 163-1130, JapanCHARGE SECTION： International Sales Section
TELEPHONE No.
： +81-3-5323-6620
FACSIMILE No.
： +81-3-5323-6621
PRODUCT No.
： 5010-29014, 5010SDS No.
： 5010-29014
Research use only.
2. HAZARDS IDENTIFICATIONGHS CLASSIFICATIONHAZARDS SYMBOL： Skin corrosion/irritation： Category 1
Eye damage/irritation： Category 1
Specific target organ toxicity (Single exposure)： Category 3(respiratory irritation)
Specific target organ toxicity (Repeated exposure)： Category 1<respiratory system>
Hazardous to the aquatic environment - Acute hazard： Category 1
Hazardous to the aquatic environment - Chronic hazard： Category 1：： Danger：
Cause severe skin burns and eye damage
Cause serious eye damage
May cause respiratory irritation
Cause damage to respiratory system through prolonged or repeated expo
sureH400
Very toxic to aquatic life
H410
Very toxic to aquatic life with long lasting effects
PRECAUTIONARY STATEMENTS ：P260
Do not breathing dust/fume/gas/mist/vapours/spray.
P264
Wash hands thoroughly after handling.
P270
Do not eat, drink or smoke when using this product.
P271
Use only outdoors or in a well-ventilated area.
P280
Wear protective gloves/protective clothing/eye protection/face protection.
P273
Avoid release to the environment.
P310
Immediately call a POISON CENTER or doctor.
P301+P330+P331
IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.
P303+P361+P353
IF ON SKIN or hair: Take off immediately all contaminated clothing. Rinse skin with water.
P304+P340
IF INHALED: Remove person to fresh air and keep comfortable for breathing.
P305+P351+P338
IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P314
Get medical attention if you feel unwell.
P363
Wash contaminated clothing before reuse.
P391
Collect spillage.
P403+P233
Store in a well-ventilated place. Keep container tightly closed.
P405
Store locked up.
P501
Dispose of contents/container in accordance with all applicable regulations.
SIGNAL WORD
HAZARD STATEMENTS
H314
H318
H335
H372

PRODUCT NAME ： 10% Silver Nitrate-impregnated Silicagel
SDS No.5010-29014

Revised date

3. COMPOSITION/INFORMATION ON INGREDIENTSCHEMICAL IDENTITY： Mixture
CHEMICALCHEMICALCONTENTNAME
FORMULA

April 15, 2019

2/5 page

CAS RNTSCA
INVENTRY

EINECS No.

Silver Nitrate

10 %AgNO37761-88-8

Listed231-859-3

Silicagel90 %SiO 2112926-00-8

Listed-4. FIRST AID MEASURES
GENERAL ADVICEINHALATIONSKIN CONTACTEYE CONTACTINGESTION： Wash off immediately with soap and plenty of water. In the case of respirable
dust, use self-contained breathing apparatus and dust impervious protectivesuit. Use personal protective equipment.
： Move victim to fresh air. If breathing is difficult, give oxygen. If irritation
persists, consult a physician.
： Remove contaminated clothes and shoes, rinse skin with plenty of water orshower. Use soap to help assure removal. If irritation persists, consult aphysician.
： Remove any contact lenses at once. Flush eyes well with flooding large
amounts of running water for at least 15 minutes. Assure adequate flushing byseparating the eyelids with sterile fingers. If irritation persists, consult aphysician. Never rub your eyes.
： Rinse mouth, give plenty of water to dilute the substance. Do not induce
vomiting. Never give anything by mouth to an unconscious person. Consult aphysician.

5. FIRE FIGHTING MEASURES
EXTINGUISHING MEDIA： Powder, foam (alcohol foam), carbon dioxide, water spray.
FIRE & EXPLOSION HAZARDS： Toxic and irritating dust, fumes or smoke may be emitted.
SPECIAL PROTECTIVE EQUIPMENT FOR FIRE FIGHTERS： Fireman should wear normal protective equipment (full bunker gear) andpositive-pressure self-contained breathing apparatus.
6. ACCIDENTAL RELEASE MEASURESPERSONAL PRECAUTIONS： Remove ignition sources and ventilate the area. In case of insufficientventilation, wear suitable respiratory equipment. Avoid raising dust and avoid
contact with skin and eyes.
ENVIRONMENTAL PRECAUTIONS： Prevent spills from entering sewers, watercourses or low areas.
Comply with local disposal regulations.
METHODS FOR CLEANING UP： Do not touch spilled material without suitable protection. After material iscompletely picked up, wash the spill site with soap and water and ventilate thearea. Pull all wastes in a plastic bag for disposal and seal it tightly. Remove,clean, or dispose contaminated clothing.
7. HANDLING AND STORAGE
HANDLING

STORAGEINCOMPATIBLE PRODUCTS： In case of insufficient ventilation, wear suitable respiratory equipment.
Avoid contact with eyes, skin, and clothing. Avoid prolonged or repeatedexposure. Handle this product with suitable protection.
After using this product, dispose of contents/container in accordance with allapplicable regulations and appropriate ways.
： Store away from sunlight, heat and all ignition sources in well-ventilated dryplace. Keep container tightly closed.
： Strong oxidizers, acids, reductants.

PRODUCT NAME ： 10% Silver Nitrate-impregnated Silicagel
SDS No.5010-29014

Revised dateApril 15, 2019

3/5 page

8. EXPOSURE CONTROL/PERSONAL PROTECTION
ENGINEERING MEASURES： Use exhaust ventilation to keep airborne concentrations below exposure limits.
Use adequate ventilation.
VENTILATION： Local Exhaust ; Necessary, Mechanical(General) ; Recommended
CONTROL PARAMETERSCHEMICALACGIH
OSHA PELNIOSH RELNAME
Silver Nitrate
TWA 0.01 mg/m3
TWA 0.01 mg/m3 (as Ag) TWA 0.01 mg/m3 (as Ag)
Inhalable dust TWA=10mg/m3 ,TWA 20mppcf
TWA 6mg/m3
Silica gel
Respirable dust TWA=3mg/m3(80mg/m3 /%SiO2 )(as amorphous silica)(as PNOS)(as amorphous silica)
PERSONAL PROTECTIONRESPIRATORY PROTECTION

HAND PROTECTION
EYE PROTECTION
SKIN PROTECTION： Half or full face piece respirator, self-contained breathing apparatus, supplied
air respirator, etc. Use respirators approved under appropriate government
standards and follow all regulations.
： Safety gloves： Safety glasses(goggles)： Protective clothing

9. PHYSICAL AND CHEMICAL PROPERTIESAPPEARANCE： White - slightly grayish white
PHYSICAL STATE： Solid(Powder)
ODOR： No data available
pH： Strong acid (in water)
BOILING POINT： No data available
MELTING POINT： No data available
FLASH POINT： No data available
FLAMMABILITY： No data available
AUTOIGNITION TEMPERATURE ： No data available
VAPOR PRESSURE： No data available
SPECIFIC GRAVITY (DENSITY) ： No data available
SOLUBILITY INWater： Insoluble
Organic solvent： Insoluble
PARTITION COEFFICIENT ;n-octanol/water： No data available
DECOMPOSITION TEMPERATURE： No data available
10. STABILITY AND REACTIVITY
REACTIVITY： Stable under recommended using and storage conditions.
Color gradually from gray to black by sunlight.
CHEMICAL STABILITY： No data available
CONDITION TO AVOID： Sunlight, heat, moisture, contact with incompatible materials.
INCOMPATIBILE MATERIALS： Acidic materials, oxidants, reductants, alkaline compounds
HAZARDOUS DECOMPOSITION PRODUCTS： No data available

11. TOXICOLOGICAL INFORMATIONACUTE TOXICITY -oral： This product is not classified.
(Silver Nitrate)： Rat LD50=1,170 mg/kg(IUCLID,2000)
ACUTE TOXICITY -dermal： The classification is not possible in this product.
ACUTE TOXICITY -inhalation： The classification is not possible in this product.
SKIN CORROSION/IRRITATION ： This product is classified in Category 1.
(Silver Nitrate)： It has been described that this substance causes corrosion to the skin (CICAD44(2003)). In addition, chemical burns due to contact with this substance havebeen reported in occupational exposure (ATSDR(1990)). In addition, thissubstance is classified into Category “C; R34” in EU DSD classification and“Skin Corr. 1B H314” in EU CLP classification.

PRODUCT NAME ： 10% Silver Nitrate-impregnated Silicagel
SDS No.5010-29014

Revised date

April 15, 2019

4/5 page： This product is classified in Category 1.
： The substance has been described as causing severe corrosiveness to theeyes (CICAD 44(2003)). In addition, chemical burns due to eye contact havebeen reported in occupational exposure (ATSDR(1990)). In addition, thissubstance is classified into Category “C; R34” in EU DSD classification and“Skin Corr. 1B H314” in EU CLP classification.
(Silica gel)
： Mild conjunctival redness in eye irritation tests(OECD TG 404, Precipitatedsilica(Sident9)) using rabbits (SIDS (2006)、ECETOC JACC (2006)).
Slight or no irritation in eye irritation tests(Precipitated silica) using rabbits(SIDS (2006)).
SKIN SENSITIZATION： The classification is not possible in this product.
GERM CELL MUTAGENICITY： The classification is not possible in this product.
CARCINOGENICITY： The classification is not possible in this product.
REPRODUCTIVE TOXICITY： The classification is not possible in this product.
SPECIFIC TARGET ORGAN TOXICITY - single exposure ： This product is classified in Category 3.
(Silver Nitrate)： The substance is corrosive and airway irritant (ATSDR(1990), PATTY(6th,2012)). In humans, exposure to dust inhalation causes irritation of airway
mucus, acute oral poisoning symptoms such as burning sensation or pai
n in the mouth, salivation, vomiting, abdominal pain, diarrhea, severe gas
troenteritis, decreased blood pressure, decreased respiratory rate, dizzine
ss, Convulsions, diaphragmatic myopathy, coma, central nervous systemdisorders, death have been reported (HSDB(Access on September 2014)).
There is no data for experimental animals.
(Silica gel)
： Irritating to respiratory tract (SIDS (2006), ECETOC JACC (2006))
SPECIFIC TARGET ORGAN TOXICITY - repeated exposure ： This product is classified in Category 1.
(Silver Nitrate)： Twenty-five out of 30 workers exposed to silver dust for less than 1 year to over 10years at the silver nitrate and silver oxide manufacturing plants have upper
respiratory tract irritation symptoms (sneezing, runny nose, stuffy nose, sore throatpain) There are descriptions that 10 persons complained of abdominal pain (severepain and reduced by antacid) (ATSDR(1990), ACGIH(7th, 2001)). Among them,abdominal pain may be due to the effect of mucous membrane irritation that orallyingested a part of dust, and it is a symptom of a few cases (one third of the whole),
and description of other digestive symptoms such as diarrhea and vomiting It wasthought that it should not be targeted for the target organ. On the other hand, in theexperimental animals, rats were administered a drinking dose of 222 mg Ag / kg /day (equivalent to 349.6 mg / kg / day) to rats for 37 weeks, and increased mortality
was observed after 23 weeks. There is no description of organ toxicity other thansilverosis (ACGIH(7th,2001)). In addition, in a study in which 89 mg Ag / kg / day(equivalent to 140 mg / kg / day) was administered to rats for nine months. Although
it has been described that ventricular hypertrophy was observed (ATSDR(1990),
ACGIH(7th,2001)), cardiovascular effects have not been reported in human andother animal studies, and the results are reliable. It is said that there is no(ATSDR(1990)). Besides this, there is no data available for classification inexperimental animals.
ASPIRATION HAZARD： The classification is not possible in this product.
EYE DAMAGE/EYE IRRITATION(Silver Nitrate)

12. ECOLOGICAL INFORMATION
Hazardous to the aquatic environment - Acute hazard –： This product is classified in Category 1.
(Silver Nitrate)： Crustacean(Daphnia magna) 48hr-EC50=0.0014 mg/L(0.0009 mg Ag/L)(CICADs 44,2002)
Hazardous to the aquatic environment - Chronic hazard –： This product is classified in Category 1.
(Silver Nitrate)： When chronic toxicity data are used, the environmental kinetics for inorg
anic compounds are unknown, and there are 60 days LOEC = 0.00016
mg/LCICADs 44,2002) of fish (rainbow trout). When using acute toxicity data for trophic levels where chronic toxicity data are not available, the environmental dynamics of inorganic compounds are unknown, and 48 hours EC50 = 0.0014 mg/L(0.0009 mg for crustaceans(Daphnia magna)Ag/L)(CICADs 44,2002).

PRODUCT NAME ： 10% Silver Nitrate-impregnated Silicagel
SDS No.5010-29014

Revised dateApril 15, 2019

5/5 page

BIODEGRADABILITY： No data available
BIOACCUMULATIVE POTENTIAL ： No data available
MOBILITY IN SOIL
： No data available
HAZARDOUS TO THE OZONE LAYER： Not listed in Montreal Protocol list.
13. DISPOSAL INFORMATION
Dispose in a hazardous-waste site in accordance with all applicable regulations. Any disposal practice must be incompliance with country, local, state, and federal laws and regulations (contact country, local or state environment
agency for specific rules).
14. TRANSPORT INFORMATIONIATAUN NUMBER： 3260
UN PROPER SHIPPING NAME ： CORROSIVE SOLID, ACIDIC, INORGANIC, N.O.S. (10%Silver Nitrate-impregnated Silicagel)
CLASS： 8, Corrosives
PACKING GROUP： III
ADR/RID： 3260, Corrosives
DOT： 3260, Corrosives
MARINE POLLUTANT： Not classified
15. REGULATORY INFORMATIONFor classification and labeling of chemicals in accordance with the applicable rules and regulations in the EU or eachcountry, refer to GHS classification of this product (See Section 2).
US REGULATION
EU REGULATION： OSHA HCS 2012/29 CFR 1910.1200： CLP Regulation ((EC) No. 1272/2008)

16. OTHER INFORMATIONNOTICE:The information contained in the SDS description is applicable exclusively to the chemical substance identified
herein and for its intended use as an analytical reference standard or reagent and to the unit quantity intended forthat purpose. The information does not relate to, and may not be appropriate for, any application or larger quantityof the substance described. Our products are intended for the use by individuals possessing sufficient technicalskill and qualification on use the material potential hazardous chemical. Accordingly, no representation or warranty,
express or implied, with respect to merchantability and fitness for a particular purpose is made with respect to theinformation contained herein.
Attention:
This product in terms of chemical identity and the unit amount provide is intended for use in chemical analysis andnot for human consumption, nor any other purpose.