いわて東北メディカル・メガバンク機構

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主な論文・著作・業績①Nasu, T., Satoh, M., Hachiya, T., Sutoh, Y., Ohmomo, H., Hitomi, S., Taguchi, S., Kikuchi, H., Kobayashi, T.,Takahashi, Y., Osaki, T., Morino, Y., Sobue, K., Shimizu, A., Sasaki, M., 2021. A genome-wide association study forhighly sensitive cardiac troponin T levels identified a novel genetic variation near a RBAK-ZNF890P locus in theJapanese general population. Int J Cardiol 329, 186–191. https://doi.org/10.1016/j.ijcard.2020.12.019②Sutoh, Y., Hachiya, T., Suzuki, Y., Komaki, S., Ohmomo, H., Kakisaka, K., Wang, T., Takikawa, Y., Shimizu, A.,
2020. ALDH2 genotype modulates the association between alcohol consumption and AST/ALT ratio among
middle-aged Japanese men: a genome-wide G × E interaction analysis. Sci Rep 10, 16227.
https://doi.org/10.1038/s41598-020-73263-1

いわて東北須藤洋一

メディカル・メガバンク機構

免疫学
特命講師

博士（医学）

進化生物学
分子生物学

③Suzuki, S., Goto, A., Nakatochi, M., Narita, A., Yamaji, T., Sawada, N., Katagiri, R., Iwagami, M., Hanyuda, A.,Hachiya, T., Sutoh, Y., Oze, I., Koyanagi, Y.N., Kasugai, Y., Taniyama, Y., Ito, H., Ikezaki, H., Nishida, Y., Tamura, T.,
Mikami, H., Takezaki, T., Suzuki, S., Ozaki, E., Kuriki, K., Takashima, N., Arisawa, K., Takeuchi, K., Tanno, K.,Shimizu, A., Tamiya, G., Hozawa, A., Kinoshita, K., Wakai, K., Sasaki, M., Yamamoto, M., Matsuo, K., Tsugane, S.,Iwasaki, M., 2021. Body mass index and colorectal cancer risk: A Mendelian randomization study. Cancer Sci 112,1579–1588. https://doi.org/10.1111/cas.14824④Zempo, H., Kim, S.-J., Fuku, N., Nishida, Y., Higaki, Y., Wan, J., Yen, K., Miller, B., Vicinanza, R., Miyamoto-Mikami,E., Kumagai, H., Naito, H., Xiao, J., Mehta, H.H., Lee, C., Hara, M., Patel, Y.M., Setiawan, V.W., Moore, T.M.,
Hevener, A.L., Sutoh, Y., Shimizu, A., Kojima, K., Kinoshita, K., Arai, Y., Hirose, N., Maeda, S., Tanaka, K., Cohen, P.,
2021. A pro-diabetogenic mtDNA polymorphism in the mitochondrial-derived peptide, MOTS-c. Aging (Albany NY)
13, 1692–1717. https://doi.org/10.18632/aging.202529

いわて東北メディカル・メガバンク機構

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主な論文・著作・業績①Takuya Osaki, Mamoru Satoh, Fumitaka Tanaka, Kozo Tanno, Yuji Takahashi, Takahito Nasu, Kiyomi Sakata,
Yoshihiro Morino, Kenji Sobue, and Makoto Sasaki. The Value of a Cystatin C-based Estimated Glomerular
Filtration Rate for Cardiovascular Assessment in a General Japanese Population:Results From the Iwate Tohoku
Medical Megabank Project. J Epidemiol 2020;30(6):260-267.
②Takuya Osaki, Mamoru Satoh, Fumitaka Tanaka, Kozo Tanno, Yuji Takahashi, Takahito Nasu, Kiyomi Sakata,
Yoshihiro Morino. The Longitudinal Changes in Cystatin C-based Estimated Glomerular Filtration Rate is
Associated to Cardiovascular Events in a General Japanese Population. The 84th Annual Scientific Meeting of theいわて東北
大﨑拓也

メディカル・メガバンク機構

Japanese Circulation Society. July 27-August 2, 2020.

特命助教

博士(医学)

循環内科学③Takuya Osaki, Mamoru Satoh, Fumitaka Tanaka, Kozo Tanno, Yuji Takahashi, Takahito Nasu, Kiyomi Sakata,
Yoshihiro Morino. Cystatin C-based Estimated Glomerular Filtration Rate for a Cardiovascular Assessment in aGeneral Japanese Population: The Iwate Tohoku Medical Megabank Project. The 83rd Annual Scientific Meeting ofthe Japanese Circulation Society. March 29-31, 2019.
④Takuya Osaki, Mamoru Satoh, Yuji Takahashi, Kozo Tanno, Takahito Nasu, Kiyomi Sakata, Motoyuki Nakamura,
Yoshihiro Morino, Atsushi Hozawa, Hideyasu Kiyomoto.Relationship between Cystatin C-based Estimated GFRand Biomarkers of Cardiovascular Disease in a General Population: The Tohoku Medical Megabank Project :The
81st Annual Scientific Meeting of the Japanese Circulation Sosiety.March 17-19, 2017

いわて東北メディカル・メガバンク機構

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主な論文・著作・業績①Yuka Kotozaki, Kozo Tanno, Kiyomi Sakata, Kotaro Otsuka, Ryohei Sasaki, Nobuyuki Takanashi, Mamoru Satoh,Atsushi Shimizu, Makoto Sasaki. Association between Social Isolation and Total Mortality after the Great East
Japan Earthquake in Iwate Prefecture: Findings from the TMM CommCohort Study. International Journal ofEnvironmental Research and Public Health 19(7) 4343 (2022)②Hiroto Kikuchi, Takahito Nasu, Mamoru Satoh, Yuka Kotozaki, Kozo Tanno, Koichi Asahi, Hideki Ohmomo,
Takamasa Kobayashi, Satoru Taguchi, Yoshihiro Morino, Atsushi Shimizu, Kenji Sobue, Makoto Sasaki.
Association between total type I collagen N-terminal propeptide and coronary artery disease risk score in thegeneral Japanese population. International journal of cardiology. Heart & vasculature 41 101056 (2022)

いわて東北
事崎由佳

メディカル・特命助教

メガバンク機構

臨床心理学関連③Yuka Kotozaki, Kozo Tanno, Kiyomi Sakata, Eri Takusari, Kotaro Otsuka, Hiroaki Tomita, Ryohei Sasaki,

博士

認知脳科学関連

Nobuyuki Takanashi, Takahiro Mikami, Atsushi Hozawa, Naoki Nakaya, Naho Tsuchiya, Tomohiro Nakamura, Akira（情報科学）

衛生学および公衆Narita, Yasuyuki Taki, Atsushi Shimizu, Jiro Hitomi, Mamoru Satoh, Makoto Sasaki. Association between the social

衛生学分野関連：

isolation and depressive symptoms after the great East Japan earthquake: findings from the baseline survey of the

実験系を含まない

TMM CommCohort study. BMC Public Health 21(1) 925 (2021)④Yuka Kotozaki, Mamoru Satoh, Kozo Tanno, Hideki Ohmomo, Ryo Otomo, Fumitaka Tanaka, Takahito Nasu,Satoru Taguchi, Hiroto Kikuchi, Takamasa Kobayashi, Atsushi Shimizu, Kiyomi Sakata, Jiro Hitomi, Kenji Sobue,
Makoto Sasaki. Plasma Xanthine Oxidoreductase Activity Is Associated with a High Risk of Cardiovascular Disease
in a General Japanese Population. International Journal of Environmental Research and Public Health 18(4) 1894
(2021)⑤Yuka Kotozaki. Horticultural activity improves postpartum women’s cognitive function: Preliminary evidence
from an exploratory pilot study. Cogent Psychology 7(1) 1851003 (2020)①Komaki S., Shiwa Y., Furukawa R., Hachiya T., Ohmomo H., Otomo R., Satoh M., Hitomi J., Sobue K., Sasaki M.,Shimizu A. (2018) iMETHYL: an integrative database of human DNA methylation, gene expression, and genomicvariation. Human Genome Variation . 5: 18008.
②Komaki S., Sutoh Y., Kobayashi K, Saito S, Saito Tanaka C, Igawa T, Lau Q (2020) Hot spring frogs (Buergeriajaponica) prefer cooler water to hot water. Ecology and Evolution .10: 9466-9473.

いわて東北
小巻翔平

メディカル・メガバンク機構

進化生物学
特命助教

博士（理学）

多様性生物学③Tadaka S., Hishinuma E., Komaki S., Motoike N.I., Kawashima J., Saigusa D., Inoue J., Takayama J., Okamura Y.,

生態学

Aoki Y., Shirota M., Otsuki A., Katsuoka F., Shimizu A., Tamiya G., Koshiba S., Sasaki M., Yamamoto M., Kinoshita
K. (2021) jMorp updates in 2020: large enhancement of multi-omics data resources on the general Japanese
population. Nucleic Acids Research . 49:D536-D544.
④Komaki,S. (2021) Widespread misperception about a major East Asian biogeographic boundary exposed throughbibliographic survey and biogeographic meta-analysis. Journal of Biogeography . 48: 2375-2386.

いわて東北メディカル・メガバンク機構

氏名所属

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主な論文・著作・業績①Otsuka-Yamasaki, Y., Inanami, O., Shino, H., Sato, R., Yamasaki, M.: Characterization of a novel nicotinamide
adenine dinucleotide-cytochrome b5 reductase mutation associated with canine hereditary methemoglobinemia. J
Vet Med Sci. 2021; 83(2): 315-321.

獣医内科学（血液いわて東北山崎

弥生

メディカル・病・人獣共通感染特命助教

博士（獣医学）メガバンク機構症）
分子生物学②Kiatpakdee, B., Sato, K., Otsuka, Y., Arashiki, N., Tsumita, T., Otsu, W., Yamamoto, A., Kawata, L., Yamazaki, J.,
Sugimoto, Y., Takada, K., Mohandas, N., Inaba, M.: Cholesterol-binding protein TSPO2 coordinates maturation andproliferation of terminally differentiating erythroblasts. J Biol Chem. 2020. 295(23): 8048-8063.
③Masuda, M., Otsuka-Yamasaki, Y., Shiranaga, N., Iguchi, A., Uchida, N., Sato, R., Yamasaki, M.: Retrospective
study on intercurrent pancreatitis with Babesia gibsoni infection in dogs. J Vet Med Sci. 2019. 81(11): 1558-1563.
④Sato, R., Uchida, N., Kawana, Y., Tozuka, M., Kobayashi, S., Hanyu, N., Konno, Y., Iguchi, A., Otsuka-Yamasaki,Y., Kuramochi, K., Yamasaki, M.: Epidemiological evaluation of cats associated with feline polycystic kidneydisease caused by the feline PKD1 genetic mutation in Japan. J Vet Med Sci. 2019. 81(7): 1006-1011.
①Minabe, S., Iwata, K., Tsuchida, H., Tsukamura, H., and Ozawa, H. (2021). Effect of diet-induced obesity on
Kiss1/Tac3/Pdyn gene expressions in the arcuate nucleus and luteinizing hormone secretion in sex hormoneprimed male and female rats. Peptides, 170546.
②Minabe, S., Nakamura, S., Fukushima, E., Sato, M., Ikegami, K., Goto, T., Sanbo, M., Hirabayashi, M., Tomikawa,J., Imamura, T., et al. (2020). Inducible Kiss1 knockdown in the hypothalamic arcuate nucleus suppressed pulsatile

いわて東北楠詩織

メディカル・メガバンク機構

生殖内分泌学特命助教

博士（農学）

secretion of luteinizing hormone in male mice. J Reprod Dev 66, 396-375.

神経内分泌学
繁殖生物学③Minabe, S., Sato, M., Inoue, N., Watanabe, Y., Magata, F., Matsuda, F., Uenoyama, Y., Ozawa, H., andTsukamura, H. (2019). Neonatal Estrogen Causes Irreversible Male Infertility via Specific Suppressive Action on
Hypothalamic Kiss1 Neurons. Endocrinology 160, 1223-1233.
④Tatebayashi, R., Nakamura, S., Minabe, S., Furusawa, T., Abe, R., Kajisa, M., Morita, Y., Ohkura, S., Kimura, K.,
and Matsuyama, S. (2021). Gene-expression profile and postpartum transition of bovine endometrial side
population cellsdagger. Biol Reprod 104, 850-860.