内科学講座

氏名所属

職名取得学位

糖尿病・代謝・内分泌内科分野

専門分野

主な論文・著作・業績①Takebe N, Tanno K, Ohmomo H, Hangai M, Oda T, Hasegawa Y, Takanashi N, Sasaki R, Shimizu A, Sasaki A,Sakata K, Sasaki M, Ishigaki Y. Weight Gain After 20 Years of Age is Associated with Unfavorable Lifestyle andIncreased Prevalence of Metabolic Disorders. Diabetes Metab Syndr Obes. 2021;14:2065-2075.
②Hasegawa Y, Takahashi Y, Kezuka Y, Obara W, Kato Y, Tamura S, Onodera K, Segawa T, Oda T, Sato M, Nata K,Nonaka T, Ishigaki Y. Identification and Analysis of a Novel NR0B1 Mutation in Late-Onset Adrenal Hypoplasia
Congenita and Hypogonadism. J Endocr Soc. 2020; 5(2):bvaa176.
③Ishigaki Y, Strizek A, Aranishi T, Arai N, Imaoka T, Cai Z, Maegawa H. Glucagon-Like Peptide-1 Receptor Agonist

石垣泰

内科学講座糖尿病・代謝・内分泌内科分野教授

医学博士

代謝学(糖代謝）

Utilization in Type 2 Diabetes in Japan: A Retrospective Database Analysis (JDDM 57). Diabetes Ther.
2021;12(1):345-361④Matsushita Y, Hasegawa Y, Takebe N, Onodera K, Shozushima M, Oda T, Nagasawa K, Honma H, Nata K, Sasaki
A, Ishigaki Y. Serum C-X-C motif chemokine ligand 14 levels are associated with serum C-peptide and fatty liverindex in type 2 diabetes mellitus patients. J Diabetes Investig. 2021, 12(6):1042-1049.
⑤Oda T, Satoh M, Nagasawa K, Sasaki A, Hasegawa Y, Takebe N, Ishigaki Y. The Effects of Imeglimin on the Daily
Glycemic Profile Evaluated by Intermittently Scanned Continuous Glucose Monitoring: Retrospective, SingleCenter, Observational Study. Diabetes Ther. 2022 Jul 27. doi: 10.1007/s13300-022-01298-w.
①Matsui M, Takahashi Y, Takebe N, Takahashi K, Nagasawa K, Honma H, Oda T, Ono M, Nakagawa R, Sasai T,Togashi H, Hangai M, Kajiwara T, Taneichi H, Ishigaki Y, Satoh J. Response to the dipeptidyl peptidase-4 inhibitors
in Japanese patients with type 2 diabetes might be associated with a diplotype of two single nucleotide
polymorphisms on the interleukin-6 promoter region under a certain level of physical activity. J Diabetes Investig.
2015 Mar;6(2):173-81.
②Takarabe D, Rokukawa Y, Takahashi Y, Goto A, Takaichi M, Okamoto M, Tsujimoto T, Noto H, Kishimoto M,Kaburagi Y, Yasuda K, Yamamoto-Honda R, Tsukada K, Honda M, Teruya K, Kajio H, Kikuchi Y, Oka S, Noda M.
Autoimmune diabetes in HIV-infected patients on highly active antiretroviral therapy. J Clin Endocrinol Metab.

高橋義彦

内科学講座糖尿病・代謝・内分泌内科分野

准教授

医学博士

2010; 95:4056-60.
代謝学・内分泌学③Takahashi Y, Noda M, Tsugane S, Kuzuya T, Ito C, Kadowaki T. Prevalence of diabetes estimated by plasma
glucose criteria combined with standardized measurement of HbA1c among health checkup participants on
Miyako Island, Japan. Diabetes Care 2000; 8: 1092-1096.
④Takahashi Y, Kadowaki H, Ando A, Quin JD, MacCuish AC, Yazaki Y, Akanuma Y, Kadowaki T. Two aberrant
splicings caused by mutations in the insulin receptor gene in cultured lymphocytes from a patient with RabsonMendenhall's syndrome. J.Clin.Invest. 1998; 101: 588-594.
⑤Takahashi Y, Kadowaki H, Momomura K, Fukushima Y, Orban T, Okai T, Taketani Y, Akanuma Y, Yazaki Y,Kadowaki T. A homozygous kinase-defective mutation in the insulin receptor gene in a patient withleprechaunism. Diabetologia 1997; 40: 412-420.

内科学講座

氏名所属

職名

取得学位

糖尿病・代謝・内分泌内科分野

専門分野

主な論文・著作・業績①Hasegawa Y. New perspectives on obesity-induced adipose tissue fibrosis and related clinical manifestations.
Endocrine Journal. 2022 Jul 28;69(7):739-748②Hasegawa Y, Takahashi Y, Kezuka Y, Obara W, Kato Y, Tamura S, Onodera K, Segawa T, Oda T, Sato M, Nata K,Nonaka T, Ishigaki Y. Identification and Analysis of a Novel NR0B1 Mutation in Late-Onset Adrenal Hypoplasia
Congenita and Hypogonadism. J Endocrine Society. 2020 Nov 13;5(2): bvaa176.
③Matsushita Y, Hasegawa Y, Takebe N, Onodera K, Shozushima M, Oda T, Nagasawa K, Honma H, Nata K, Sasaki

長谷川豊

内科学講座糖尿病・代謝・内分泌内科分野

特任准教授

医学博士

代謝学（糖尿病）

A, Ishigaki Y. Serum C-X-C motif chemokine ligand 14 levels are associated with serum C-peptide and fatty liver
index in type 2 diabetes mellitus patients. J Diabetes Investig. 2020 Oct 15.
④Hasegawa Y, Ikeda K, Chen Y, Alba DL, Stifler D, Shinoda K, Hosono T, Maretich P, Yang Y, Ishigaki Y, Chi J,Cohen P, Koliwad SK, Kajimura S.Repression of Adipose Tissue Fibrosis through a PRDM16-GTF2IRD1 Complex
Improves Systemic Glucose Homeostasis.Cell Metabolism. 2018 Jan 9;27(1):180-194⑤Altshuler-Keylin S, Shinoda K, Hasegawa Y, Ikeda K, Hong H, Kang Q, Yang Y, Perera RM, Debnath J, Kajimura S.
Beige Adipocyte Maintenance Is Regulated by Autophagy-Induced Mitochondrial Clearance.Cell Metab. 2016 Aug
24. pii: S1550-4131(16)30378-3.
① Fujita N, Baba T, Tomiyama T, Kodama T, Kato N. Hyperinsulinaemia and blood pressure withinsulinom. BMJ. 1992; 304(6835):1157.
② 藤田典子、小沼冨男、後藤尚、日向豪史. 耐糖能軽度低下, インスリン抵抗性, 高インスリン血症併存例における交感神経機能及び腎ナトリウム排泄能についての研究. 弘前医学. 1994; 46(2): 121-130.
② 武部典子、藤丸潔、松原潔、種市春仁、歳弘真貴子、吉成仁、石田弥、金子能人、澤田哲伸、佐々木正孝、佐藤俊一．悪性貧血を合併した抗グルタミン酸脱炭酸酵素抗体陽性の緩徐進行型1型糖尿病の一例．糖尿病．
2000; 43: 367-371.

武部典子

内科学講座糖尿病・代謝・内分泌内科分野

講師

医学博士

代謝学・内分泌学③ 武部典子、横山仁、三浦正憲、他. 橋本病を合併し抗GAD抗体が異常高値を示したIDDMの1例. 岩手医学誌. 1998;
50(1):105-109.
④Matsushita Y, Hasegawa Y, Takebe N, Onodera K, Shozushima M, Oda T, Nagasawa K, Honma H, Nata K, SasakiA, Ishigaki Y. Serum C-X-C motif chemokine ligand 14 levels are associated with serum C-peptide and fatty liver
index in type 2 diabetes mellitus patients. J Diabetes Investig. 2021; 12(6): 1042-1049.
⑤Takebe N, Tanno K, Ohmomo H, Hangai M, Oda T, Hasegawa Y, Takanashi N, Sasaki R, Shimizu A, Sasaki A,Sakata K, Sasaki M, Ishigaki Y. Weight Gain After 20 Years of Age is Associated with Unfavorable Lifestyle andIncreased Prevalence of Metabolic Disorders. Diabetes Metab Syndr Obes. 2021; 14: 2065-2075.

内科学講座氏名所属

職名取得学位

糖尿病・代謝・内分泌内科分野

専門分野

主な論文・著作・業績①Yutaka H, Yoshihiko T, Yuichiro K, Wataru O, Yoichiro K, Shukuko T, Ken O, Toshie S, Tomoyasu O, Marino Sa,Koji N, Takamasa N, Yasushi I. Identification and Analysis of a Novel NR0B1 Mutation in Late-Onset Adrenal
Hypoplasia Congenita and Hypogonadism. J Endocr Soc. 5, 1-10, 2021.
②Yuki M, Fumitaka T, Toshie S, Kozo T, Kazuyoshi I, Kiyomi S, Masaki O, Shinichi O, Kuniaki O, Koichi A andMotuyki N. Sex differences in the influence of elevated serum uric acid levels for cardiovascular risk in the general
population with normal renal function. JIMA 72, 145-155, 2020.
③Nakamura M, Tanaka F, Segawa T, Takahashi T, Matsuura Y, Sakai T, Nishiyama O, Niiyama M, Onoda T,瀬川利恵

内科学講座糖尿病・代謝・内分泌内科分野

講師

医学博士

Koshiyama M, (on behalf of Northern Iwate Heart Disease Registry Consortium) . Temporal Trends in the
代謝学・内分泌学

Incidence and Clinical Features of Acute Myocardial Infarction in a Japanese Rural Area From 2006 to 2014. Circ J
2017; 81: 1854–1861.
④ Koeda Y, Tanaka F, Segawa T, Ohta M, Ohsawa M, Tanno K, Makita S, Ishibashi Y, Itai K, Omama S, Onoda T,
Sakata K, Ogasawara K, Okayama A, Nakamura M. Comparison between urine albumin-to-creatinine ratio andurine protein dipstick testing for prevalence and ability to predict the risk for chronic kidney disease in the generalpopulation (Iwate-KENCO study): a prospective community-based cohort study.BMC Nephrol. 2015;12;17(1):46.
⑤ Toshie S, Motoyuki N, Kazuyoshi I, Toshiyuki O, Akira O, Katsuhiko H. B-type Natriuretic Peptide Levels andRisk Factors for Congestive Heart Failure in a Japanese General Population. Int Heart J. 2005;46(3):465-75.
本間博之、松井瑞絵、佐藤隆、高橋和眞、武部典子、長澤幹、小野光隆、笹井賢良、高橋義彦、菅井保、石垣泰、佐藤本間博之

内科学講座糖尿病・代謝・内分泌内科分野

助教

代謝学（糖尿病）

譲、Non-islet cell tumor hypoglycemia caused by big IGF-II in a patient with carcinosarcoma of the uterus.、日本内科学会英文誌、54巻・24号・3165-9 、2015年12月12日
Nagasawa K, Kaneko Y, Taneichi H, Ishii M, Masaya M, Honma H, Kakino S, Takahashi K, Yoshioka Y, Satoh J:

長澤幹

内科学講座糖尿病・代謝・内分泌内科分野

助教

医学博士

代謝学（糖尿病）

Association of decrease in liver triglyceride content with increase in plasma adiponectin levels after pioglitazone
treatment in Japanese patients with type 2 diabetes. J Iwate Med Assoc 62(1): 59-66, 2010.
Oda T, Taneichi H, Takahashi K, Togashi H, Hangai M, Nakagawa R, Ono M, Matsui M, Sasai T, Nagasawa K,

小田知靖

内科学講座糖尿病・代謝・内分泌内科分野

助教

医学博士

代謝学（糖尿病）

Honma H, Kajiwara T, Takahashi Y, Takebe N, Ishigaki Y, Satoh J: Positive association of free triiodothyronine withpancreatic β-cell function in people with prediabetes: Diabet Med. 2014 Sep 26.
Satoshi Yashiro, Hiroyuki Kameda, Ai Chida, Yusuke Todate, Yutaka Hasegawa, Kan Nagasawa, Ikuko Uwano,

八代諭

内科学講座糖尿病・代謝・内分泌内科分野

助教

医学博士

代謝学（糖尿病）

Makoto Sasaki, Kuniaki Ogasawara, Yasushi Ishigaki Evaluation of Lenticulostriate Arteries Changes by 7 T
Magnetic Resonance Angiography in Type 2 Diabetes:Journal of Atherosclerosis and Thrombosis, 2018;25:10671075.
Mari Hangai, Noriko Takebe, Hiroyuki Honma, Atsumi Sasaki,Ai Morita, Rieko Nakano, Hirobumi Togashi, Riyuki

半谷真理

内科学講座糖尿病・助教

代謝・内分泌内科分野（任期付）

Nakagawa,Tomoyasu Oda, Mizue Matsui, Takayoshi Sasai, KanNagasawa, Takashi Kajiwara, Kazuma
代謝学（糖尿病）

Takahashi,Yoshihiko Takahashi, Jo Satoh, Yasushi Ishigak:Association of Advanced Glycation End Products withcoronary Artery Calcification in Japanese Subjects with Type 2 Diabetes as Assessed by Skin Autofluorescence,Journal of atherosclerosis and thrombosis, 23(10), 1178-1187, 2016 Oct 1]

佐賀敦美

内科学講座糖尿病・助教

代謝・内分泌内科分野（任期付）

代謝学（糖尿病）

内科学講座氏名

所属

職名取得学位

糖尿病・代謝・内分泌内科分野

専門分野

主な論文・著作・業績①千田 愛, 高橋 義彦, 中川 理友紀, 長澤 幹, 川島 智美, 佐藤 まりの, 瀬川 利恵, 高橋 和眞, 石垣 泰

千田愛

内科学講座糖尿病・助教

代謝・内分泌内科分野（任期付）

性HLAハプロタイプを有する膵島関連自己抗体陰性の多腺性自己免疫症候群2型の1例
代謝学（糖尿病）

糖尿病

1型糖尿病疾患抵抗2019：62(9)、514-9②千田 愛、橋本 朋子、松下 百合子、中川 理友紀、小田 知靖、長谷川 豊、武部 典子、石垣 泰：1型糖尿病の血清ア
ディポサイトカイン濃度に影響する因子の検討：Journal of Iwate Medical Association 72(1):11-20、2020