臨床薬学講座

氏名

所属

職名

取得学位

情報薬科学分野

専門分野

主な論文・著作・業績①Yonezawa, H., Ikeda, A., Takahashi, R., Endo, H., Sugawara, Y., Goto, M., Kanno, M., Ogawa, S., Nakamura, K.,
Ujiie, H., Iwatsuki, M., Hirose, T., Sunazuka, T., Uehara, Y., Nishiya, N. : Ivermectin represses Wnt/β-cateninsignaling by binding to TELO2, a regulator of phosphatidylinositol 3-kinase-related kinases./ iScience.
25(3):103912 (2022)②Nishiya, N. and Yonezawa, H. : Domestication of chemicals attacking metazoan embryogenesis: Identification of西谷直之

臨床薬学講座情報薬科学分野

教授

博士（薬学）

創薬科学

safe natural products modifying developmental signaling pathways in human. / J. Antibiotics, 74: 651–659 (2021)

腫瘍治療学③Nishiya, N., Oku, Y., Ishikawa, C., Fukuda, T., Dan, S., Mashima, T., Ushijima, M., Furukawa, Y., Sasaki, Y., Otsu,

ケミカルバイオロジー

K., Sakyo, T., Abe, M., Yonezawa, H., Ishibashi, F., Matsuura, M., Tomida, A., Seimiya, H., Yamori, T., Iwao, M.,Uehara, Y. : Lamellarin 14, a Derivative of Marine Alkaloids, Inhibits the T790M/C797S Mutant Epidermal GrowthFactor Receptor. / Cancer Sci., 112: 1963–1974 (2021)④文部科学省科学研究費補助金「課題名：ｍTORC構成因子Tel2を標的とする新規マクロライド系Wnt経路阻害薬の開発」2021〜2023年⑤米国特許

Patent No: 11,286,261 B2「Fourth-Generation EGFR Tyrosine Kinase Inhibitor」Mar. 29, 2022

①Nishiya, N., Oku, Y., Ishikawa, C., Fukuda, T., Dan, S., Mashima, T., Ushijima, M., Furukawa, Y., Sasaki, Y., Otsu,K., Sakyo, T., Abe, M., Yonezawa, H., Ishibashi, F., Matsuura, M., Tomida, A., Seimiya, H., Yamori, T., Iwao, M.,Uehara, Y. : Lamellarin 14, a Derivative of Marine Alkaloids, Inhibits the T790M/C797S Mutant Epidermal GrowthFactor Receptor. / Cancer Sci., 112: 1963–1974 (2021)②Yonezawa, H., Sugawara, A., Sakyo, T., Uehara, Y., Kawano, T., Nishiya, N. : IMU1003, an atrarate derivative,
inhibits Wnt/β-catenin signaling. / Biochem. Biophys. Res. Commun. 532: 440-445 (2020)

佐京智子

臨床薬学講座情報薬科学分野

助教

博士（医学）

細胞生物学③ Watanabe, M., Naraba, H., Sakyo, T., Kitagawa, T. : DNA damage-induced modulation of GLUT3 expression is

病態医化学

mediated through p53-independent extracellular signal-regulated kinase signaling in HeLa cells. / Mol Cancer

腫瘍生物学

Res.8, 1547-57 (2010)④ Sakyo, T., Naraba, H., Teraoka, H., and Kitagawa, T. : The intrinsic structure of glucose transporter isoforms
Glut1 and Glut3 regulates their differential distribution to detergent-resistant membrane domains in non-polarized
mammalian cells. / FEBS Journal, vol. 274, 2843-2853 (2007)⑤ Sakyo, T., and Kitagawa, T. : Differential localization of glucose transporter isoformes in non-polarized
mammalian cells: Distribution of GLUT1 but not GLUT3 to detergent-resistant membrane domains. / Biochimica
Biophysica Acta(BBA)-Biomembranes, 1567: 165-175 (2002)

臨床薬学講座

氏名所属

職名取得学位

情報薬科学分野

専門分野

主な論文・著作・業績①Yonezawa, H., Ikeda, A., Takahashi, R., Endo, H., Sugawara, Y., Goto, M., Kanno, M., Ogawa, S., Nakamura, K.,
Ujiie, H., Iwatsuki, M., Hirose, T., Sunazuka, T., Uehara, Y., Nishiya, N. : Ivermectin represses Wnt/β-cateninsignaling by binding to TELO2, a regulator of phosphatidylinositol 3-kinase-related kinases. / iScience.
7;25:103912(2022).
②Ujiie, H., Nihei, S., Nishiya, N., Goto, S., Asakura, Y., Miura, S., Hirai, D., Endo, M., Oyake, T., Ito, S., Chiba, T.,
Kudo, K. : Switching from Intravenous to Oral Tacrolimus Reduces its Blood Concentration in Paediatric Cancer

氏家悠貴

臨床薬学講座情報薬科学分野

助教

学士（薬学）

医療薬学
がん化学療法

Patients. / Anticancer Res. 41:2591-2596 (2021)③Takahashi, H., Asaka, J., Tairabune, T., Ujiie, H., Matsuura, Y., Nihei, S., Kimura, T., Chiba, T., Kudo K. : Analysis ofrisk factors for skin disorders caused by anti-epidermal growth factor receptor antibody drugs and examination ofmethods for their avoidance. / J Clin Pharm Ther, Online ahead of print. doi: 10.1111/jcpt.13475. (2021)④Oku, Y., Tareyanagi, C., Takaya, S., Osaka, S., Ujiie, H., Yoshida, K., Nishiya, N., Uehara, Y. : Multimodal Effects ofSmall Molecule ROCK and LIMK Inhibitors on Mitosis, and Their Implication as Anti-Leukemia Agents. / PLoS
One, 9:e92402. (2014)⑤氏家悠貴「小児がん領域における多職種連携で薬剤師ができること」日本病院薬剤師会東北ブロック第9回学術大会
シンポジウム6「薬薬・多職種・施設間…連携でさらに広がるがん領域の薬剤師業務」, 秋田市, 2019年6月1日.