May 14, 2024

Grant Theme Decided for 17th Mandom International
Research Grants on Alternatives to Animal Experiments
Mandom Corporation(head office: Osaka City, President Executive Officer & Director: Ken
Nishimura, hereinafter referred to as “Mandom”) is working to develop alternatives to animal
experiments based on the concept of animal welfare. As part of this research effort, the company
has been holding its Mandom International Research Grants on Alternatives to Animal
Experiments with full cooperation from The Japanese Society for Alternatives to Animal
Experiments since FY2007. This will be the 17th time the event is held. After rigorous examination,it has been decided that grants will be issued regarding three research themes.
Grant Themes
When applications for the 17th Mandom International Research Grants on Alternatives to Animal
Experiments first started back on November 1, 2023, the deadline for applications was set toJanuary 1, 2024 . After careful examination, Mandom has decided that this year’s research grants
will be given under the following three themes.

Research grant providers (affiliation) withouthonorific titles
Nobuhiko Kojima（Graduate School of Nanobioscience, Yokohama CityUniversity）
Wei Liu（Dalian University of Technology）
Yasuhiro Ishihara（Graduate School of Integrated Sciences for Life,Hiroshima University）

Research theme
Development of translucent spheroid

Comparative studies on toxic effects of chemicals in
2D human bronchial epithelia cells and 3D airwayorganoids
Development of a novel device for skin culture
reflecting outdoor environment

Research grants for the themes listed above are being given from April 2024.
Considerations are currently underway regarding the 18th Mandom International Research
Grants on Alternatives to Animal Experiments. Mandom will issue another press release once
details have been decided.

mandom corp.
Public Relations Div.
mail: press@mandom.com
Please contact us in Japanese or English.

URL: https://www.mandom.co.jp/en/

*For reference[About the Mandom International Research Grants on Alternatives to Animal Experiments]
The Mandom International Research Grants on Alternatives to Animal Experiments has been
held since FY2007 with the aim of promoting and widely recommending research in alternatives
to animal testing and encouraging more active research in alternative fields.
During the 17th Mandom International Research Grants on Alternatives to Animal Experiments,
Mandom collected research themes from around the world, mainly Asia, regarding alternatives
to animal testing. The conditions were as follows:・Requirements for entering the 17th Mandom International Research Grants on
Alternatives to Animal Experiments
1) Theme
Research regarding alternatives to animal testing(any field of study)2) Grant Amount
500,000 - 2M yen per grant, total of 3M yen/year
3) Schedule
Nov.1, 2023
Applications begin
Jan. 31, 2023
Application deadline
Feb.1, 2024
Selection begins
Early Apr. 2024
Grant theme is decided
Until Mar. 31, 2025
Grant period(1 year)[Mandom’s Stance on Developing Alternatives to Animal Testing]In the wake of the EU ban on animal testing for cosmetics issued in March 2013, the global
effort to develop alternatives to animal experiments has sped up. The developed replacements
are now coming on stream as new methods of safety evaluation.
In Japan, the principles of the 3Rs to promote animal welfare are guiding the way in developing
these methods. The 3Rs are namely: Replacement(Using other methods that do not involveanimals); Reduction(Decreasing the amount of use of animals); and Refinement(Lessening thesuffering caused to animals). Discussion and development are ongoing on testing methods thatbring greater precision in predicting and evaluating products and their effectiveness.
At Mandom, our policy is not to use any animal testing. The safety of cosmetics products wemanufacture and market are assured through the use of replacement methods as well as oftesting on human subjects(including patch test and skin test). We are highly aware that thedevelopment of alternatives to animal experiments focusing on greater experiment precision isan essential part of further raising safety standards, and we have been awarding international
research grants on alternatives to animal experiments in addition to our current drive topromote the development of replacement methods to animal testing.
We make every effort when it comes to securing the safety of the cosmetics products wemanufacture and market, which is something we promote as an initiative for one of the materialissues(materiality) within our sustainability strategy, namely "maintaining/enhancing thecorporate base." Our everlasting mission is expanding and strengthening our Dedication toService , and we will continue our efforts as a company that recognizes the value of its existencefrom all stakeholders.