Safety Data Sheet
Material Name: Antibody solution

SDS ID: F-1068
In compliance with Regulation(EC) 1907/2006 (REACH) as
amended* * *Section 1 - IDENTIFICATION OF THE SUBSTANCE / MIXTURE AND OF THE COMPANY /UNDERTAKING* * *1.1 Product Identifier:Product Identifier: Antibody solution(Sialylated HEG1 (SKM9-2) HC)
Product code: 498331F
Substance Registration Number(s)This product and its components are not subject to REACH.
1.2 Relevant Identified Uses of the Substance or Mixture and Uses Advised Against
Identified Uses
immunohistochemical use
Reagent type: Bottle
498331F : Sialylated HEG1 (SKM9-2) HC; 1 ml x 1
Uses Advised Against
Use in accordance with supplier's recommendations.
1.3 Details of the supplier of the safety data sheet
Nichirei Biosciences Inc.
6-19-20, Tsukiji, Chuo-Ku
Tokyo, Japan

Telephone number: +81-3-3248-2207
Email: n1060x005@nichirei.co.jp

1.4 Emergency Telephone Number+81-3-3248-2207 (9:00-17:00 Japan time)* * *Section 2 - HAZARDS IDENTIFICATION* * *2.1 Classification of the Substance or Mixture
Classification according to Regulation (EC) No 1272/2008
No classification is assigned, based on classification criteria. Review the entire data sheet for any additional
information which did not result in a GHS classification.
2.2 Label Elements
Labelling according to Regulation (EC) No 1272/2008:
Symbol(s)None needed according to classification criteria.
Signal Word
None needed according to classification criteria.
Hazard Statement(s)None needed according to classification criteria.
Precautionary Statement(s)Prevention
None needed according to classification criteria.
Response
None needed according to classification criteria.
Storage____________________________________________________________
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Safety Data Sheet
Material Name: Antibody solution

SDS ID: F-1068
In compliance with Regulation(EC) 1907/2006 (REACH) as
amendedNone needed according to classification criteria.
Disposal
Dispose in accordance with all applicable regulations.
2.3 Other Hazards
No additional information is available.

* * *Section 3 - COMPOSITION / INFORMATION ON INGREDIENTS* * *
CAS
EC No
Registration No
Not Available--26628-22-8
247-852-1--

Component
Synonyms

1272/2008(CLP)

Percent

Aqueous protein containing solution

--

>99.9

Sodium azide

Acute Tox. 2(Oral) H300
Aquatic Acute 1
H400
Aquatic Chronic
1 H410EU Acid VTox
EUH032<0.1* * *Section 4 - FIRST AID MEASURES* * *4.1 Description of First Aid Measures
Inhalation
If adverse effects occur, remove to uncontaminated area. If breathing is difficult, oxygen should be administeredby qualified personnel. Get medical attention.
Skin
Wash with plenty of soap and water. If skin irritation occurs: Get medical advice/attention.
Eyes
Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue
rinsing. Get medical attention if irritation develops or persists.
Ingestion
If swallowed, get medical attention.
4.2 Most Important Symptoms and Effects, both Acute and Delayed
Acute
No information on significant adverse effects.
DelayedNo information on significant adverse effects.
4.3 Indication of any Immediate Medical Attention and Special Treatment Needed
Treat symptomatically and supportively.

* * *Section 5 - FIRE FIGHTING MEASURES* * *5.1 Extinguishing Media____________________________________________________________
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Safety Data Sheet
Material Name: Antibody solution

SDS ID: F-1068
In compliance with Regulation(EC) 1907/2006 (REACH) as
amendedUse extinguishing agents appropriate for surrounding fire.
Unsuitable Extinguishing MediaDo not use high-pressure water streams.
5.2 Special Hazards Arising from the Substance or Mixture
Negligible fire hazard.
Thermal Decomposition Products
Combustion: miscellaneous decomposition products
5.3 Advice for Firefighters
Fire Fighting Measures
Move container from fire area if it can be done without risk. Cool containers with water spray until well after thefire is out.
Protective Equipment and Precautions for Firefighters
Wear personal protective clothing and equipment such as self-contained breathing apparatus (SCBA) for
protection against possible exposure.

* * *Section 6 - ACCIDENTAL RELEASE MEASURES* * *6.1 Personal Precautions, Protective Equipment and Emergency Procedures
Wear personal protective clothing and equipment, see Section 8.
6.2 Environmental Precautions
Avoid release to the environment.
6.3 Methods and Material for Containment and Cleaning up
Absorb with sand or other non-combustible material. Collect spilled material in appropriate container for disposal.
Keep unnecessary people away, isolate hazard area and deny entry.
6.4 Reference to Other Sections
See Section 7 for Handling Procedures. See Section 8 for Personal Protective Equipment recommendations. See
Section 13 for Disposal Considerations.

* * *Section 7 - HANDLING AND STORAGE* * *7.1 Precautions for Safe Handling
Avoid breathing vapor or mist. Avoid contact with skin and eyes. Wash thoroughly after handling.
7.2 Conditions for Safe Storage, Including any Incompatibilities
Store and handle in accordance with all current regulations and standards.
7.3 Specific End Use(s)immunohistochemical use* * *Section 8 - EXPOSURE CONTROLS / PERSONAL PROTECTION* * *8.1 Control Parameters
Component Exposure Limits
Sodium azide (26628-22-8)
EU (IOELV):

Austria:

Belgium:

0.1 mg/m3 TWA
0.3 mg/m3 STEL
Possibility of significant uptake through the skin
0.1 mg/m3 TWA [TMW]
0.3 mg/m3 STEL [KZW] (4 X 15 min)skin notation
Skin____________________________________________________________
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Safety Data Sheet
Material Name: Antibody solution

Bulgaria:

Croatia:

Denmark:
Estonia:

Finland:France:Germany (TRGS):
Gibraltar:

Germany (DFG):
Greece:Hungary:
Ireland:

Italy:

Latvia:Lithuania:

Malta:

Netherlands:

Poland:Portugal:

SDS ID: F-1068
In compliance with Regulation(EC) 1907/2006 (REACH) as
amended

0.1 mg/m3 TWA
0.3 mg/m3 STEL
Skin notation
0.1 mg/m3 TWA [GVI]
0.3 mg/m3 STEL [KGVI]Skin Notation
0.1 mg/m3 TWA
Potential for cutaneous absorption
0.1 mg/m3 TWA
0.3 mg/m3 STEL
Skin notation
0.1 mg/m3 TWA
0.3 mg/m3 STEL
Potential for cutaneous absorption
0.1 mg/m3 TWA [VME] (restrictive limit)
0.3 mg/m3 STEL [VLCT] (restrictive limit)
Risk of cutaneous absorption
0.2 mg/m3 TWA AGW (exposure factor 2)
Skin notation
0.3 mg/m3 STEL
0.1 mg/m3 TWA
0.2 mg/m3 TWA MAK (inhalable fraction)
0.4 mg/m3 Peak (inhalable fraction)
0.1 ppm TWA; 0.3 mg/m3 TWA
0.1 ppm STEL; 0.3 mg/m3 STEL
0.1 mg/m3 TWA [AK]0.3 mg/m3 STEL [CK]0.1 mg/m3 TWA (as NaN3)
0.3 mg/m3 STEL
Potential for cutaneous absorption
0.1 mg/m3 TWA Media Ponderata nel Tempo
0.3 mg/m3 STEL Breve termine
skin - potential for cutaneous absorption
0.1 mg/m3 TWA
0.3 mg/m3 STEL
skin - potential for cutaneous exposure
0.1 mg/m3 TWA [IPRD]
0.3 mg/m3 STEL [TPRD]
Skin notation
0.1 mg/m3 TWA
0.3 mg/m3 STEL
possibility of significant uptake through the skin
0.1 mg/m3 TWA
0.3 mg/m3 STEL
skin notation
0.1 mg/m3 TWA [NDS]
0.3 mg/m3 STEL [NDSCh]
0.1 mg/m3 TWA [VLE-MP] (indicative limit value)
0.3 mg/m3 STEL [VLE-CD] (indicative limit value)____________________________________________________________
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Safety Data Sheet
Material Name: Antibody solution

Romania:

Slovak Republic:

Slovenia:

Spain:

Sweden:United Kingdom:SDS ID: F-1068
In compliance with Regulation(EC) 1907/2006 (REACH) as
amended0.29 mg/m3 Ceiling [VLE-CM] (as NaN3); 0.11 ppm Ceiling [VLE-CM] (as Hydrazoic
acid, vapor)skin - potential for cutaneous exposure (indicative limit value)
0.1 mg/m3 TWA
0.3 mg/m3 STEL
Skin notation
0.1 mg/m3 TWA
0.3 mg/m3 Ceiling
Potential for cutaneous absorption
0.1 mg/m3 TWA
0.3 mg/m3 STEL
Potential for cutaneous absorption
0.1 mg/m3 TWA [VLA-ED] (indicative limit value)
0.3 mg/m3 STEL [VLA-EC]
skin - potential for cutaneous exposure
0.1 mg/m3 LLV
0.3 mg/m3 STVSkin notation
0.1 mg/m3 TWA (as NaN3)
0.3 mg/m3 STEL (as NaN3)
Potential for cutaneous absorption

Component Biological Limit Values
There are no biological limit values for the component(s) of this product.
Derived No Effect Levels (DNELs)
No DNELs available.
Predicted No Effect Concentrations (PNECs)
No PNECs available.

8.2 Exposure Controls
Appropriate Engineering Controls
Provide local exhaust ventilation system. Ensure compliance with applicable exposure limits.
Personal Protective Equipment
Eye / Face Protection
Wear splash resistant safety glasses. (EN 166) Provide an emergency eye wash fountain and quick drench
shower in the immediate work area.
Skin Protection
Wear appropriate chemical resistant clothing. (EN 340)
Glove Recommendations
Wear appropriate chemical resistant gloves. (EN 374)
Respiratory Protection
If airborne contaminant levels exceed recommended exposure limits, use CEN/EN Standard applicable
respiratory protection appropriate for employee exposure levels.
Consult with a health and safety professional for specific respirators appropriate for your use.
Environmental Exposure Controls
Avoid release to the environment.

____________________________________________________________
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Safety Data Sheet
Material Name: Antibody solution

SDS ID: F-1068
In compliance with Regulation(EC) 1907/2006 (REACH) as
amended* * *Section 9 - PHYSICAL AND CHEMICAL PROPERTIES* * *9.1 Information on Basic Physical and Chemical Properties
Physical State:
Color:
Odor:
pH:
Boiling Point:
Decomposition
Temperature:
LEL:
Vapor Pressure:
Density:
Water Solubility:
Coeff. Water/Oil Dist:
Viscosity:
Explosive Properties:

Liquidcolorlessodorless
Not available
Not available
Not available

Appearance:
Physical Form:
Odor Threshold:
Melting Point:
Flash Point:
Evaporation Rate:colorless liquid
liquidNot available
Not available
Not available
Not available

Not available
Not available
Not available
Not available
Not available
Not available
Not available

UEL:
Vapor Density (air = 1):
Specific Gravity (water = 1):
Log KOW:
Auto Ignition Temperature:
Oxidizing Properties:
Flammability (solid, gas):

Not available
Not available
Not available
Not available
Not available
Not available
Not applicable

9.2 Other Information
No additional information is available.

* * *Section 10 - STABILITY AND REACTIVITY* * *10.1 Reactivity
No reactivity hazard is expected.
10.2 Chemical Stability
Stable at standard temperatures and pressure.
10.3 Possibility of Hazardous Reactions
Will not polymerize.
10.4 Conditions to Avoid
None known.
10.5 Incompatible Materials
None known.
10.6 Hazardous Decomposition Products
Thermal Decomposition Products
Combustion: miscellaneous decomposition products* * *Section 11 - TOXICOLOGICAL INFORMATION* * *11.1 Information on Toxicological Effects
Acute and Chronic Toxicity
Component Analysis - LD50/LC50
Sodium azide (26628-22-8)
Oral LD50 Rat 27 mg/kg
Irritation / Corrosivity____________________________________________________________
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Safety Data Sheet
Material Name: Antibody solution

SDS ID: F-1068
In compliance with Regulation(EC) 1907/2006 (REACH) as
amendedMay cause irritation.
Respiratory Sensitisation
No information available for the product.
Skin Sensitisation
No information available for the product.
Germ Cell Mutagenicity
No information available for the product.
Carcinogenicity
Component Carcinogenicity
No information available for the product.
Reproductive Toxicity
No information available for the product.
Specific Target Organ Toxicity - Single Exposure
No target organs identified.
Specific Target Organ Toxicity - Repeated Exposure
No target organs identified.
Aspiration Hazard
No information available for the product.

* * *Section 12 - ECOLOGICAL INFORMATION* * *12.1 Toxicity
Component Analysis - Aquatic Toxicity
Sodium azide (26628-22-8)
Fish:

96 Hr LC50 Oncorhynchus mykiss: 0.8 mg/L; 96 Hr LC50 Lepomis macrochirus: 0.7
mg/L; 96 Hr LC50 Pimephales promelas: 5.46 mg/L [flow-through]12.2 Persistence and Degradability
No information available for the product.
12.3 Bioaccumulative Potential
No information available for the product.
12.4 Mobility in Soil
No information available for the product.
12.5 Results of PBT and vPvB Assessment
No information available.
EU - Interim Strategy for Management of PBT and vPvB Substances (PBT Assessments)
No components of this material are listed.
12.6 Other Adverse Effects
No additional information is available.

* * *Section 13 - DISPOSAL CONSIDERATIONS* * *13.1 Waste Treatment Methods
13.1.1 Product/Packaging Disposal
For disposal within the EC, use the appropriate code according to European Waste Catalogue (EWC).
13.1.2 Waste Treatment Relevant Information
Dispose in accordance with all applicable regulations.

____________________________________________________________
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Safety Data Sheet
Material Name: Antibody solution

SDS ID: F-1068
In compliance with Regulation(EC) 1907/2006 (REACH) as
amended13.1.3 Sewage Disposal Relevant Information
Prevent entry into sewers, drains, ditches, underground or confined spaces and waterways.
13.1.4 Other Disposal Recommendations
Dispose in accordance with all applicable regulations.

* * *Section 14 - TRANSPORT INFORMATION* * *Transportation
Not regulated as dangerous goods
International Bulk Chemical CodeThis material contains no chemical required by the IBC Code to be identified as dangerous chemicals in bulk

* * *Section 15 - REGULATORY INFORMATION* * *15.1 Safety, Health and Environmental Regulations / Legislation Specific for the Substance or Mixture
EU - REACH (1907/2006) - Annex XIV List of Substances Subject to Authorisation
No components of this material are listed.
EU - REACH (1907/2006) - Article 59(1) Candidate List of Substances for Eventual Inclusion in Annex XIV
No components of this material are listed.
EU - REACH (1907/2006) - Annex XVII Restrictions of Certain Dangerous Substances, Mixtures and Articles
No components of this material are listed.
Germany Regulations
Germany Water Classification
Sodium azide (26628-22-8)
ID Number 636, hazard class 2 - hazard to waters
Denmark Regulations
Environmental Protection Agency List of Undesirable Substances
No components of this material are listed.
Threshold of Exposure Concentrations of VOCs
No components of this material are listed.
France Water Pollution
No components of this material are listed.
Inventory
Substance Analysis - Inventory
Component
Sodium azideCAS
26628-22-8

EEC
EIN

15.2 Chemical Safety Assessment
No chemical safety assessment has been carried out for the substance/mixture.

* * *Section 16 - OTHER INFORMATION* * *
16.1
16.2

Indication of changes
New SDS: November 12, 2020
Key / Legend to abbreviations and acronyms used in the safety data sheet
ACGIH - American Conference of Governmental Industrial Hygienists; ADR - European Road Transport; AIHA American Industrial Hygiene Association; CAS - Chemical Abstracts Service; CERCLA - Comprehensive
Environmental Response, Compensation, and Liability Act; CLP - Classification, Labelling and Packaging; DNEL -____________________________________________________________
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Safety Data Sheet
Material Name: Antibody solution

16.3
16.4
16.5
16.6
16.7

SDS ID: F-1068
In compliance with Regulation(EC) 1907/2006 (REACH) as
amended

Derived No Effect Level; DOT - Department of Transportation; DSD - Dangerous Substances Directive(67/548/EEC); DSL - Domestic Substances List; EC50 - Effective Concentration, 50%; EEC - European Economic
Community; EIN (EINECS) - European Inventory of Existing Commercial Chemical Substances; ELN (ELINCS) European List of Notified Chemical Substances; EPA - Environmental Protection Agency; IARC - International
Agency for Research on Cancer; IATA - International Air Transport Association; IBC Code - International Bulk
Chemical Code; IMDG - International Maritime Dangerous Goods; Kow - Octanol/water partition coefficient; LC50
- Lethal Concentration, 50%; LD50 - Lethal Dose, 50%; LEL - Lower Explosive Limit; NFPA - National Fire
Protection Agency; NIOSH - National Institute for Occupational Safety and Health; NTP - National Toxicology
Program; OSHA - Occupational Safety and Health Administration; PNEC - Predicted No Effect Concentration;
REACH - Registration, Evaluation, Authorisation and Restriction of Chemicals; RID - European Rail Transport;
SARA - Superfund Amendments and Reauthorization Act; STEL - Short-term Exposure Limit; TDG Transportation of Dangerous Goods; TSCA - Toxic Substances Control Act; TWA - Time Weighted Average; UEL- Upper Explosive Limit; WHMIS - Workplace Hazardous Materials Information System
Key literature references and sources for data
Available upon request
Methods used for classification of mixture according to Regulation (EC) No 1272/2008
Available upon request
Full text of H- phrases in Section 3
There is no text of H-phrase.
Training Advice
Read the Safety Data Sheet before handling product.
Other Information
Disclaimer: Supplier gives no warranty whatsoever, including the warranties of merchantability or of fitness for aparticular purpose. Any product purchased is sold on the assumption the purchaser shall determine the quality
and suitability of the product. Supplier expressly disclaims any and all liability for incidental, consequential or any
other damages arising out of the use or misuse of this product. No information provided shall be deemed to be arecommendation to use any product in conflict with any existing patent rights.

End of Sheet F-1068____________________________________________________________
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