Program
Moderator: Joy J. Goto

11:30

Registration

12:50-13:00

Opening ceremonySpecial Lectures 1Yong-Sun Kim

Chairs: Shirou Mohri and Eun-Kyoung Choi

TimePresentation Title

Speakers

13:00-13:40

The influence of aging and inflammation on oral prion disease pathogenesis
10-minute Q&A

Neil A.
Mabbott

13:40-14:20

Study of synthetically generated prions
10-minute Q&A

Jiyan Ma

14:20-14:40

Coffee BreakOral Presentations from Selected Posters 1 (Presentation & Audience participation: 10 min per person)
Chairs: Katsumi Doh-ura and Chongsuk RyouTime

14:40-15:30

Presentation TitleSpeakers

Poster 8Distinct
origins of dura mater graft-associated Creutzfeldt-Jakob disease:past and future problems

Atsushi
Kobayashi

Poster 5Involvement of the dorsal root ganglion in GSS with P105L mutation

FumikoFurukawa

Poster 2C SF analysis of patients with human prion disease

Katsuya SatohPoster 16 G lycosaminoglycans can be served as substitutes of nucleic acids forin vitro amplification of insect cell-derived abnormal form of prion protein

Morikazu
ImamuraPoster 28 C omparison of anti-prion mechanism of four different anti-prion
compounds, anti-PrP monoclonal antibody 44B1, pentosan polysulfate,chlorpromazine and U18666A in prion-infected mouse neuroblastoma cells

TakeshiYamasaki

Hot Topics Session 1Chairs: Hidehiro Mizusawa and Jae-Woo Kim

TimePresentation Title

Speakers

15:30-15:55

Involvement of CD14 in neuropathogenesis of prion diseases
5-minute Q&AMotohiroHoriuchi

15:55-16:20

Activation of AMPK-ULK1 pathway contributes greatly to autophagy activation in thebrains of scrapie infected rodents and cultured cells
5-minute Q&A

Xiao-PingDong

16:20-16:45

Vesicular trafficking in prion disease
5-minute Q&A

SuehiroSakaguchi

16:45-17:10

The yin and yang in the regulation of prion propagation
5-minute Q&AChongsukRyou

17:00-18:30

Poster Session

18:00-18:30

Executive APSPR committee Meeting

19:00

Reception

Program - DAY 1 : Sunday July 6•7

Program - DAY 1 : Sunday July 6

DAY 1 : Sunday July 6

Asian Pacific Prion Symposium 2014 in Jeju

Program
Program - DAY 2: Monday July 7

Moderator: Joy J. Goto

DAY 2: Monday July 7
9:00-9:10

Opening

Oral Presentations from Selected Posters 2 (Presentation & Audience participation: 10 min per person)
Chairs: Xiao-Ping Dong and Jae-Il Kim
Time

9:10-10:00

Presentation Title

Speakers

Poster 41 P rion protein gamma-cleavage: a novel proteolytic event

Victoria Lewis

Poster 35 P rion proteins binding of Aldolase A of intestinal M cells in a PrP-binding
protein

YuyaNagasawa

Poster 33 Innate immune responses modulate prion replication in primary CGN/CAS

Sang-Gyun
Kang

Poster 18 Infectivity, neurotoxicity and PrPSc accumulation in BSE-affected miceKohtaro
Miyazawa

Poster 24 M
 odification of Lys residue on the pathogenic prion isoform withεε
N -carboxymethyl (N -carboxymethyl linkage to the pathogenic prion isoform)

Yeong-Gon
Choi

Special Lecture 2

Chair: Noriyuki Nishida

Time

Presentation Title

10:00-10:40

Cerebrospinal fluid in prion diseases to understand early disease pathology
10-minute Q&A

10:40-11:00

Coffee BreakHot Topics Session 2Speakers
Inga Zerr

Chair: Steven John Collins and Masahito Yamada

Time

Presentation Title

Speakers

11:00-11:25

Yeast prion promotes acquired cellular adaptation to environmental stress5-minute Q&AMotomasa
Tanaka11:25-11:50

Prion infection dysregulates cholesterol metabolism and requires the preservation ofa membrane environment for efficient transmission
5-minute Q&A

Andrew F. Hill

11:50-12:15

Peptidylarginine deiminases and citrullinated proteins: New targets for prion
pathogenesis
5-minute Q&A

12:15-12:30

Awarding Ceremony

12:30-12:40

Closing Remarks

8•Program - DAY 2: Monday July 7

Eun-Kyoung
Choi

Masahito
Yamada