O Labeled
Stable Isotope
Water Imaging

17

Symposium

Schedule(JST)Opening Remarks

13：00-O Labeled Stable Isotope Water MR Imagingand Aquaporin-4

13：10-

17

Water Movement in AQP4-knockout Mouse Brain after MCA
Occlusion
National Institutes for Quantum Science and Technology / Takayuki OBATA

Functional Analysis of AQP-4 Using Water and Solute
Tracers in MRIRadiology, Hokkaido University Hospital / Daisuke KATO

Modulation of Brain Water Dynamics through AQP-4
Regulation and Its Implications for Disease Treatment
Strategies
Brain Research Institute, Niigata University / Hironaka IGARASHIIntermission

14：10-14：25

Attempt to Visualize Neurofluid Using
Oxygen-17O Labeled Stable Isotope Water

March 9th

Neurofluid MR Imaging using CSF Tracers in Rat Models

Admission

Radiology, Hokkaido University Hospital / Naoya KINOTA

Free ofCharge

Sat 2024

13:00 to 18:50

14：25-

Analysis of Brain Water Dynamics using H 217O MRI in ALS
Model Mice Administered 17O Labeled Water
Central Institute for Experimental Animals / Yuji KOMAKI

Cerebrospinal Fluid Dynamics using 17O-Labeled Water inMacaca fascicularis
Radiology, Shiga University of Medical Science / Yoshiyuki WATANABEMR Imaging of Neurofluid in Humans using 17O-LabeledWaterRadiology, Hokkaido University Hospital / Hiroyuki KAMEDAIntermission

15：45-16:00

Application of 17O Labeled Stable Isotope Water
in Human

16：00-

Visualization of Human Intraocular Water Dynamics using
1H-MRI with 17O Labeled Water
National Institutes for Quantum Science and Technology /Moyoko TOMIYASUMR Imaging of Intrapympanically Administered 17O Labeled
Water in the Human Inner Ear: Insight into Lymphatic
Dynamics and Vestibular Function
Pre-registration

Format : HybridOnsite

School of Medicine Centennial Hall,
Graduate School of Medicine,
Hokkaido University

Department of Radiology Nagoya University, Graduate School of Medicine/ Shinji NAGANAWA

Development of MRI Evaluation Modalities for theDiagnosis of Articular Cartilage Lesions

Department of Orthopaedic Surgery, Hokkaido University Graduate
School of Medicine / Tomohiro ONODERAIntermission
Integration with Other Fields

Department of Gastroenterological Surgery 1, Hokkaido University
Graduate School of Medicine / Moto FUKAI

Pre-registration Online

Cryogenic Isotope Microscope from Stars to Life

Creative Research Institution, Hokkaido University / Naoya SAKAMOTO

Intermission

https://us06web.zoom.us/webinar/register/WN̲QrxotaNpQhOb7yYcGJtYvASpecial Lecture

Lectures will be broadcast on YouTube after March 9thContactInformation

17：15-

D2O Containing Organ Preservation Solution Suppresses Cold
Storage and Reperfusion Injury: Emerging Needs to Assess
Solvent Isotope Effect of D2O Inside and Outside the Body

URL/ https://forms.gle/Nc19qPvCTt5Vy2Dh6

Nonproﬁt organization

Sponsored by

17：00-17：15

17：55-18：10
18：10-

Physiological and Pathological Roles of Aquaporin-4 in
Glymphatic System
Department of Pharmacology, Keio University School of Medicine/ Masato YASUIMedical Image Lab.

Closing Remarks

18：40-

Department of Diagnostic Imaging,
Hokkaido University Graduate School of Medicine and Faculty of Medicine
N15,W7,Kita ward, Sapporo,Japan, 060-8638 Southeast Research Building 1F ES1・106-2

TEL

011-706-7779

E-mailnatsuki-sato@med.hokudai.ac.jp