pHLys Red - Lysosomal Acidic pH Detection
Safety Data Sheetaccording to Regulation (EC) No. 1907/2006 (REACH) with its amendment Regulation (EU) 2015/830
Issue date: 8/24/2022 Version: 1.0

SECTION 1: Identification of the substance/mixture and of the company/undertaking
1.1. Product identifier
Product form
Trade nameProduct code

: Substance: pHLys Red - Lysosomal Acidic pH Detection: L2651.2. Relevant identified uses of the substance or mixture and uses advised against
1.2.1. Relevant identified uses
No additional information available
1.2.2. Uses advised against
Recommended uses and restrictions: for research use only

1.3. Details of the supplier of the safety data sheet
Dojindo Laboratories
Tabaru 2025-5 Mashiki-machi, Kamimashiki-gun, Kumamoto 861-2202, JapanSECTION 2: Hazards identification
2.1. Classification of the substance or mixture
Classification according to Regulation (EC) No. 1272/2008 [CLP]Not classified
Adverse physicochemical, human health and environmental effects
To our knowledge, this product does not present any particular risk, provided it is handled in accordance with good occupational hygiene and safety
practice.

2.2. Label elements
Labelling according to Regulation (EC) No. 1272/2008 [CLP]No labelling applicable

2.3. Other hazards
No additional information available

SECTION 3: Composition/information on ingredients3.1. Substances
Name

Product identifier

pHLys Red - Lysosomal Acidic pH Detection%Classification according toRegulation (EC) No.
1272/2008 [CLP]< 100Not classified

3.2. Mixtures
Not applicable

SECTION 4: First aid measures
4.1. Description of first aid measures
First-aid measures after inhalation
First-aid measures after skin contact
First-aid measures after eye contact
First-aid measures after ingestion::::

Remove person to fresh air and keep comfortable for breathing.
Wash skin with plenty of water.
Rinse eyes with water as a precaution.
Call a poison center or a doctor if you feel unwell.

4.2. Most important symptoms and effects, both acute and delayed
No additional information available

8/24/2022 (Version: 1.0)

JP - en

1/7

pHLys Red - Lysosomal Acidic pH Detection
Safety Data Sheetaccording to Regulation (EC) No. 1907/2006 (REACH) with its amendment Regulation (EU) 2015/830

4.3. Indication of any immediate medical attention and special treatment needed
Treat symptomatically.

SECTION 5: Firefighting measures
5.1. Extinguishing media
Suitable extinguishing media: Water spray. Dry powder. Foam.

5.2. Special hazards arising from the substance or mixture
Hazardous decomposition products in case of fire

: Toxic fumes may be released.

5.3. Advice for firefighters
Protection during firefighting: Do not attempt to take action without suitable protective equipment. Self-contained
breathing apparatus. Complete protective clothing.

SECTION 6: Accidental release measures
6.1. Personal precautions, protective equipment and emergency procedures
6.1.1. For non-emergency personnel
Emergency procedures: Ventilate spillage area.

6.1.2. For emergency responders
Protective equipment: Do not attempt to take action without suitable protective equipment. For further informationrefer to section 8: "Exposure controls/personal protection".

6.2. Environmental precautions
Avoid release to the environment.

6.3. Methods and material for containment and cleaning up
Methods for cleaning up
Other information: Mechanically recover the product.
: Dispose of materials or solid residues at an authorized site.

6.4. Reference to other sections
For further information refer to section 13.

SECTION 7: Handling and storage
7.1. Precautions for safe handling
Precautions for safe handling
Hygiene measures: Ensure good ventilation of the work station. Wear personal protective equipment.
: Do not eat, drink or smoke when using this product. Always wash hands after handling theproduct.

7.2. Conditions for safe storage, including any incompatibilities
Storage conditions: Store at room temperature. Keep tightly closed.

7.3. Specific end use(s)No additional information available

SECTION 8: Exposure controls/personal protection
8.1. Control parameters
No additional information available

8.2. Exposure controls
Appropriate engineering controls:
Ensure good ventilation of the work station.

8/24/2022 (Version: 1.0)

JP - en

2/7

pHLys Red - Lysosomal Acidic pH Detection
Safety Data Sheetaccording to Regulation (EC) No. 1907/2006 (REACH) with its amendment Regulation (EU) 2015/830

Hand protection:
Protective gloves

Eye protection:
Safety glasses

Skin and body protection:
Wear suitable protective clothing

Respiratory protection:
In case of insufficient ventilation, wear suitable respiratory equipment
Personal protective equipment symbol(s):Environmental exposure controls:
Avoid release to the environment.

SECTION 9: Physical and chemical properties
9.1. Information on basic physical and chemical properties
Physical state
ColourOdour
Odour threshold
pH
Relative evaporation rate (butylacetate=1)
Melting point
Freezing point
Boiling point
Flash point
Auto-ignition temperature
Decomposition temperature
Flammability (solid, gas)
Vapour pressure
Relative vapour density at 20 °C
Relative density
Solubility
Partition coefficient n-octanol/water (Log Pow)
Viscosity, kinematic
Viscosity, dynamic
Explosive properties
Oxidising properties
Explosive limits:::::::::::::::::::::::

Solidunable to visually confirm.
odourless.
No data available
No data available
No data available
No data available
Not applicable
No data available
Not applicableNot applicable
No data available
Non flammable.
No data available
No data available
No data available
No data available
No data available
Not applicable
No data available
No data available
No data available
Not applicable

9.2. Other information
No additional information available

SECTION 10: Stability and reactivity
10.1. Reactivity
The product is non-reactive under normal conditions of use, storage and transport.

8/24/2022 (Version: 1.0)

JP - en

3/7

pHLys Red - Lysosomal Acidic pH Detection
Safety Data Sheetaccording to Regulation (EC) No. 1907/2006 (REACH) with its amendment Regulation (EU) 2015/830

10.2. Chemical stability
Stable under normal conditions.

10.3. Possibility of hazardous reactions
No dangerous reactions known under normal conditions of use.

10.4. Conditions to avoid
None under recommended storage and handling conditions (see section 7).

10.5. Incompatible materials
No additional information available

10.6. Hazardous decomposition products
Under normal conditions of storage and use, hazardous decomposition products should not be produced.

SECTION 11: Toxicological information
11.1. Information on toxicological effects
Acute toxicity (oral)
Acute toxicity (dermal)
Acute toxicity (inhalation): Not classified: Not classified: Not classified

Skin corrosion/irritation
Serious eye damage/irritation
Respiratory or skin sensitisation
Germ cell mutagenicityCarcinogenicity:::::

Reproductive toxicity: Not classified

STOT-single exposure: Not classified

STOT-repeated exposure: Not classified

Aspiration hazard: Not classified

Not classified
Not classified
Not classified
Not classified
Not classified

pHLys Red - Lysosomal Acidic pH Detection
Viscosity, kinematic

Not applicable

SECTION 12: Ecological information
12.1. Toxicity
Ecology - general
Hazardous to the aquatic environment, short-term(acute)Hazardous to the aquatic environment, long-term(chronic)
Not rapidly degradable: The product is not considered harmful to aquatic organisms nor to cause long-term adverse
effects in the environment.
: Not classified: Not classified

12.2. Persistence and degradability
No additional information available

12.3. Bioaccumulative potential
No additional information available

12.4. Mobility in soil
No additional information available

8/24/2022 (Version: 1.0)

JP - en

4/7

pHLys Red - Lysosomal Acidic pH Detection
Safety Data Sheetaccording to Regulation (EC) No. 1907/2006 (REACH) with its amendment Regulation (EU) 2015/830

12.5. Results of PBT and vPvB assessment
No additional information available

12.6. Other adverse effects
No additional information available

SECTION 13: Disposal considerations
13.1. Waste treatment methods: Dispose of contents/container in accordance with licensed collector’s sorting instructions.

Waste treatment methods

SECTION 14: Transport information
In accordance with ADR / IMDG / IATA / ADN / RID

ADR

IMDG

IATA

ADN

RID

Not applicableNot applicableNot applicableNot applicableNot applicableNot applicableNot applicableNot applicableNot applicableNot applicableNot applicableNot applicableNot applicableNot applicableNot applicableNot applicableNot applicableNot applicableNot applicable

14.1. UN number
Not applicable

14.2. UN proper shipping nameNot applicableNot applicable

14.3. Transport hazard class(es)Not applicable

14.4. Packing group
Not applicable

14.5. Environmental hazards
Not applicableNo supplementary information available

SECTION 15: Regulatory information
15.1. Safety, health and environmental regulations/legislation specific for the substance or mixture
15.1.1. EU-Regulations
No REACH Annex XVII restrictions
pHLys Red - Lysosomal Acidic pH Detection is not on the REACH Candidate List
pHLys Red - Lysosomal Acidic pH Detection is not on the REACH Annex XIV List
pHLys Red - Lysosomal Acidic pH Detection is not subject to Regulation (EU) No 649/2012 of the European Parliament and of the Council of 4 july
2012 concerning the export and import of hazardous chemicals.
pHLys Red - Lysosomal Acidic pH Detection is not subject to Regulation (EU) No 2019/1021 of the European Parliament and of the Council of 20
June 2019 on persistent organic pollutants
15.1.2. National regulations
Germany
Employment restrictions

Water hazard class (WGK)
Hazardous Incident Ordinance (12. BImSchV)
Netherlands
ABM category
SZW-lijst van kankerverwekkende stoffen
SZW-lijst van mutagene stoffen
SZW-lijst van reprotoxische stoffen – Borstvoeding

8/24/2022 (Version: 1.0)

: Observe restrictions according Act on the Protection of Working Mothers (MuSchG)
Observe restrictions according Act on the Protection of Young People in Employment(JArbSchG): Not classified according to Regulation Governing Systems for Handling Substances
Hazardous to Waters (AwSV): Is not subject of the Hazardous Incident Ordinance (12. BImSchV): A(4) - low hazard for aquatic organisms, may have longterm hazardous effects in aquaticenvironment: The substance is not listed: The substance is not listed: The substance is not listed

JP - en

5/7

pHLys Red - Lysosomal Acidic pH Detection
Safety Data Sheetaccording to Regulation (EC) No. 1907/2006 (REACH) with its amendment Regulation (EU) 2015/830

SZW-lijst van reprotoxische stoffen –Vruchtbaarheid
SZW-lijst van reprotoxische stoffen – Ontwikkeling
Switzerland
Storage class (LK): The substance is not listed: The substance is not listed: NG - Non-hazardous

15.2. Chemical safety assessment
No chemical safety assessment has been carried out

SECTION 16: Other information
Abbreviations and acronyms:
ADN

European Agreement concerning the International Carriage of Dangerous Goods by Inland Waterways

ADR

European Agreement concerning the International Carriage of Dangerous Goods by Road

ATE

Acute Toxicity Estimate

BCF

Bioconcentration factor

BLV

Biological limit value

BOD

Biochemical oxygen demand (BOD)

COD

Chemical oxygen demand (COD)

DMEL

Derived Minimal Effect level

DNEL

Derived-No Effect Level

EC-No.

European Community numberEC50

Median effective concentration

ENEuropean Standard

IARC

International Agency for Research on Cancer

IATA

International Air Transport Association

IMDG

International Maritime Dangerous Goods

LC50

Median lethal concentration

LD50

Median lethal dose

LOAEL

Lowest Observed Adverse Effect Level

NOAEC

No-Observed Adverse Effect Concentration

NOAEL

No-Observed Adverse Effect Level

NOEC

No-Observed Effect Concentration

OECD

Organisation for Economic Co-operation and Development

OEL

Occupational Exposure Limit

PBT

Persistent Bioaccumulative Toxic

PNEC

Predicted No-Effect Concentration

RID

Regulations concerning the International Carriage of Dangerous Goods by RailSDS

Safety Data Sheet

STP

Sewage treatment plant

ThOD

Theoretical oxygen demand (ThOD)

TLMMedian Tolerance Limit

VOC

Volatile Organic Compounds

CAS-No.

Chemical Abstract Service number

8/24/2022 (Version: 1.0)

JP - en

6/7

pHLys Red - Lysosomal Acidic pH Detection
Safety Data Sheetaccording to Regulation (EC) No. 1907/2006 (REACH) with its amendment Regulation (EU) 2015/830

N.O.S.

Not Otherwise SpecifiedvPvB

Very Persistent and Very Bioaccumulative

ED

Endocrine disrupting properties

The classification complies with: ATP 12SDS EU (REACH Annex II)
This product is a chemical substance and is intended to be used by persons having chemical knowledge and skill at their own discretion and risk.
This SDS was prepared with our best knowledge based on the information obtained. However, it does not provide any warranty on the data and theassessment of hazards and toxicity information be covered. For use, please investigate not only the hazards and toxicity information but also thelaws and regulations of the organization, region and country where the product be used.
In case you use the information on SDS for important decision, we strongly recommend you to confirm the source of information and the data withyour own investigation. Please be noted that the physicochemical data and contents indicated in this SDS are not guaranteed values, only a guide.
The cautions stated are for normal handling only. Additional care may be required for any special handling. The data and/or information used on thisSDS may be updated by new knowledge and/or amendments of the conventional theory. Therefore, please check the most updated version of SDS
which is available at www.dojindo.com.

8/24/2022 (Version: 1.0)

JP - en

7/7