Product Data - D12266B

Description
Purified match to C11024,
the “condensed milk” diet.

Used in Research
Obesity
Diabetes
Hypertension

ReportRepeatReviseFormula
Product # D12266B

gm%

kcal%

Protein
Carbohydrate
Fat

18.5
56.7
15.6

16.8
51.4
31.8
100

PackagingTotal
kcal/gm

4.41

Product is packed in 12.5 kg box.
Each box is identified with the
product name, description, lot
number and expiration date.

Ingredient

gm

kcal

Casein, 30 Mesh
DL-Methionine

190
3760
12Lead TimeCorn Starch
Maltodextrin 10Sucrose

21575290860
3001160

Yes. Add 10 days to delivery time.

Cellulose, BW200300Form

Butter Fat, Anhydrous
Corn Oil

44.2
118397.81062

Mineral Mix S10001
Calcium Carbonate
Sodium Chloride
Potassium Citrate, 1 H2O405.5
5.5
13.50000

Vitamin Mix V10001
Choline Bitartrate

112440

FD&C Yellow Dye #5
FD&C Red Dye #40

00.1

001042.8

4595.85-7 business days.

Gamma-Irradiation

Pellet, Powder, Liquid

Shelf Life
Most diets require storage in a cooldry environment. Stored correctly
they should last 6 months.

Control Diets
D12489B

TotalWhere NutriPhenomics Begins

Research Diets, Inc.
20 Jules Lane
New Brunswick, NJ 08901 USA
Tel: 732.247.2390
Fax: 732.247.2340
info@researchdiets.com© 2006 Research Diets, Inc. All rights reserved. D12266B--6-12

References - D12266B

ReportRepeatRevise1. Alberts, P. et al. Selective inhibition of 11ß-hydroxsteroid dehydrogenase type 1 decreases blood glucose concentrations in hyperglycaemic mice.
Diabetologia. 45:1528-1532, 2002.
2. Alberts, P. et al. Selective inhibition of 11ß-hydroxysteroid dehydrogenase type 1 improves hepatic insulin sensitivity in hyperglycemic mice strains.
Endocrinology. 144:4755-4762, 2003.
3. Turnbull, A.V., et al. Selective antagonism of the NPY Y5 receptor does not have a major effect on feeding in rats. Diabetes. 51:2441-2449, 2002.
4. Block, M.H., et al. Discovery and optimization of a series of carbozole ureas as NPY5 antagonists for the treatment of obesity. J. Med. Chem. 45:3509-3523, 2002.
5. Boustany, C.M., et al. Activation of the systemic and adipose rennin-angiotesin system in rats with diet-induced obesity andhypertension. Am. J. Physiol. Integr. Comp. Physiol. 287: R943-R949, 2004.
6. Chandler, P.C., et al. Change in CCK-8 response after diet-induced obesity and MC3/4-receptor blockade. Peptides. 25:299-306, 2004.
7. Chandler, P.C., et al. Feeding response to melanocortin agonist predicts preference for and obesity from a high-fat diet. Physiology and Behavior. 85:221-230, 2005.
8. Chen, A.S., et al. Role of the melanocortin-4 receptor in metabolic rate and food intake in mice. Transgenic Research. 9:145-154, 2000.
9. Clegg, D.J., et al. Reduced anorexic effects of insulin in obesity-prone rats fed a moderate-fat diet. Am. J. Physiol. 288:981-986, 2005.
10. DeRuisseuu, L.R., Parsons, A.D., & Overton, J.M. Adaptive thermogenesis is intact in B6 and A/J mice studied at thermoneutrality. Metabolism. 53:1417-1423, 2004.
11. Bobrian, A.D., et al. Effect of salt on hypertension and oxidative stress in a rat model of diet-induced obesity.
Am. J. Physiol. Renal Physiol. 285::F619-F628, 2003.
12. Dobrian, A.D., et al. Development of Hypertension in a rat model of diet-induced obesity. Hypertension. 35:1009-1015, 2000.
13. Dobrian, A.D., et al. Oxidative stress in a rat model of obesity-induced hypertension. Hypertension. 37:554-560, 2001.
14. Dobrian A.D. et al. Pioglitazone prevents hypertension and reduces oxidative stress in diet-induced obesity. Hypertension. 43: 48-56, 2004.
15. Ghibaudi, L., et al. Fat intake affects adiposity, comorbidity factors, and energy metabolism of Sprague-Dawley rats. Obesity Research. 10:956-963, 2002.
16. Heinrichs, Stephen. Nonexercise muscle tension and behavioral fidgeting are positively correlated with food availability/palatability and body weight in rats.
Physiology & Behavior. 79:199-207, 2003.
17. Larden, P.J., et al. Differential influence of peroxisome proliferators-activated receptors ? and -a on food intake and energy homeostasis. Diabetes. 52:2249-2259, 2003.
18. Lauterio, T. J., et al. Plasma growth hormone secretion is impaired in obesity-prone rats before onset of diet-induced obesity.
American Journal of Physiology. 275:E6-E11, 1998.
19. Lauterio, T.J., Bond, J.P. * Ulman, E.A. Development and characterization of purified diet to identify obesity-susceptible and resistant rat popuilations.
Journal of Nutrition. 124:2172-2178, 1994.
20. Lauterio, T.J., et al. Neuropeptide Y expression and endogenous leptin concentrations in a dietary model of obesity. Obesity research. 7:498-505, 1999.
21. Marsh, D.J., et al. Melanin-concentrating hormone 1 receptor-deficient mice are lean, hyperactive, and hyperphagic and have altered metabolism.
PNAS. 99:3240-3245, 2002.
22. Shen, C.P., et al. Plasma agouti-related protein level: a possible correlation with fasted and fed states in humans and rats.
Journal of Neuroendocrinology. 14:607-610, 2002.
23. Singh, K.A., et al. Acute insulin-induced elevations of circulating leptin and feeding inhibition in lean but not obese rats. Am. J. Regul. Integr. Comp.
Physiol. 289:373-379,2005.
24. Singh, D.K., et al. Phosphorylation of supernatant protein factor enhances wits ability to stimulate microsomal squalene monooxygenase.
The Journal of Biological achemistry. 278:5646-5651, 2003.
25. Strack, A.M. et, al. Regulation of body weight and carcass composition by sibutramine in rats. Obesity Research. 10:173-181, 2002.
26. Turnbull, A.V. Selective antagonism of the NPY Y5 receptor does not have a major effect on feeding in rats. Diabetes. 51:2441-2449, 2002.
27. Warden, C. H., et al. Identification of a congenic mouse line with obesity and body length phenotypes. DOI. 15:460-471, 2004.
28. Zhou, D., et al. Enhanced running wheel activity of both Mch 1r- and Pmch-deficient mice. Regulatory Peptides. 124:53-63, 2005.

Where NutriPhenomics Begins

Research Diets, Inc.
20 Jules Lane
New Brunswick, NJ 08901 USA
Tel: 732.247.2390
Fax: 732.247.2340
info@researchdiets.com© 2006 Research Diets, Inc. All rights reserved. D12266B--6-12