Kit
Product name
GroE Mix

Catalog No.

Quantity

PF004-0.5-EX

500 µL for reaction

PF004-10ML-EX

5x 2 mL for reaction

Contents
Product nameProduct No.

GroE Mix

PF004

Dil. Buf.

PF001-DB2

SAFETY DATA SHEET
Page 1 of 9
Revision date: Dec 1st, 2023
PF004 (US)Version 3

Section 1: Identification
Product identifier
Product name:Product code:

GroE Mix
PF004

Relevant identified uses of the substance or mixture and uses advised against
Relevant identified uses of the product:
This product is for research and development only.
Details of the supplier of the safety data sheet
Name:
Address:

GeneFrontier Corporation
SHARP Kashiwa Building 4F, 273-1
Kashiwa, Kashiwa-shi, Chiba 277-0005,
Japan+81-4-7137-6301+81-4-7132-7530
purefrex@genefrontier.com+81-4-7137-6301

Telephone number:Fax number:e-mail address:
Emergency telephone number:
Section 2: Hazard(s) identification

GHS classification and label elements of the product
Classification according to Hazard Communication Standard - 2012 (29 CFR 1910.1200)

Classification of the substance or mixture:

Not classified to GHS classification.

Labelling according to Hazard Communication Standard - 2012 (29 CFR 1910.1200)

Label elements:

No GHS label element.
No Signal word.

Section 3: Composition/information on ingredients
Mixture/Substance selection:

MixtureIngredient name
CAS No.
Content (%)
BufferTrade secret0.1 - 1
Mineral F
Trade secret0.1 - 2Glycerin
56-81-5
25 - 30
Note: The figures shown above are not the specifications of the product.
The specific chemical identity and/or exact percentage (concentration) of this composition
has been withheld as a trade secret.
The components not described in this component table are not listed in Table 3 of Annex VI
in EU CLP.
Product name: GroE Mix

Product No.: PF004

Page 2 of 9
Revision date: Dec 1st, 2023
PF004 (US)Version 3

Section 4: First-aid measures
Descriptions of first-aid measures
IF INHALEDIF ON SKIN (or hair)
IF IN EYESIF SWALLOWED

Remove person to fresh air and keep comfortable for breathing.
Call a POISON CENTER or doctor/physician if you feel unwell.
Wash with plenty of soap and water.
If skin irritation occurs: Get medical advice/attention.
Rinse cautiously with water for several minutes. Remove contactlenses, if present and easy to do. Continue rinsing.
If eye irritation persists: Get medical advice/attention.
Rinse mouth. Call a POISON CENTER or doctor/physician if you feelunwell.

Most important symptoms/effects, both acute and delayedSpecific information on symptom and effect are unknown.
Indication of any immediate medical attention and special treatment needed
Information on indication of any immediate medical attention and special treatment needed is
not available.
Section 5: Fire-fighting measures
Extinguishing media
Suitable extinguishing media:
Use appropriate extinguishing media suitable for surrounding facilities.
Unsuitable extinguishing media:
Unsuitable extinguishing media data is not available.
Specific hazards arising from the substance or mixture
No information available
Advice for firefighters
Specific fire-fighting measures:
Evacuate non-essential personnel to safe area.
Special protective equipment and precautions for fire-fighters:
Firefighters should wear self-contained breathing apparatus with full face peace operated
positive pressure mode.

Product name: GroE Mix

Product No.: PF004

Page 3 of 9
Revision date: Dec 1st, 2023
PF004 (US)Version 3

Section 6: Accidental release measures
Personal precautions, protective equipment and emergency procedures
Keep unauthorized personnel away. Wear proper protective equipment.
Environmental precautions
Prevent spills from entering sewers, watercourses, or low areas.
Do not wash away into sewers or waterway.
Methods and materials for containment and cleaning up
Absorb spill with inert material (dry sand, earth, et al), then place in a chemical waste container.
Section 7: Handling and storage
Precautions for safe handling
Preventive measures:
Avoid contact with skin.
Avoid contact with eyes.
Safety treatments:
Use personal protective equipment as required.
Advice on general occupational hygiene:
Do not get in eyes, on skin, or on clothing.
Do not eat, drink or smoke when using this product.
Wash hands thoroughly after handling.
Storage
Conditions for safe storage:
Keep container tightly closed.
Store at temperatures not exceeding designated temperature.
Storage temperature upper limit:-20 °C/ -4 °F
Container and packaging materials for safe handling:
No information available.

Product name: GroE Mix

Product No.: PF004

Page 4 of 9
Revision date: Dec 1st, 2023
PF004 (US)Version 3

Section 8: Exposure controls/personal protection
Control parameters
Adopted value
Adopted value in ACGIH is not available.
OSHA-PEL(Glycerin)
NIOSH-REL(Glycerin)

TWA: 5 mg/m3 (Respirable fraction)
TWA: 15 mg/m3 (Total dust)
See Appendix D

Exposure controls
Appropriate engineering controls:
Eye wash station should be available.
Washing facilities should be available.
Individual protection measures, such as personal protective equipment:
Hand protection

Eye protection
Skin and body protection

Wear protective gloves.
Recommended material(s): impermeable or chemical resistantrubber.
Wear safety glasses with side-shields or chemical safety
goggles.
Wear protective clothing.

Section 9: Physical and chemical properties
Information on basic physical and chemical properties
Physical state: Liquid
Colour: Clear
Odour: None
Odour threshold data is not available.
Melting point/Freezing point data is not available.
Boiling point or initial boiling point data is not available.
Boiling range data is not available.
Flammability (gases, liquids and solids): Non-flammable
Lower and upper explosion limit/flammability limit data is not available.
Flash point data is not available.
Auto-ignition temperature data is not available.
Decomposition temperature data is not available.
pH: 7-8
Kinematic viscosity data is not available.
Solubility
Solubility in water: Soluble
Solubility in solvent data is not available.
n-Octanol/water partition coefficient data is not available.
Vapor pressure data is not available.
Product name: GroE Mix

Product No.: PF004

Page 5 of 9
Revision date: Dec 1st, 2023
PF004 (US)Version 3

Density and/or relative density data is not available.
Relative vapor density (Air=1) data is not available.
Particle characteristics: Not applicable.
Evaporation rate data is not available.
Other information
No information available.
Section 10: Stability and reactivity
Reactivity
Reactivity data is not available.
Chemical stability
Stable under normal storage/handling conditions (see Section 7).
Possibility of hazardous reactions
Possibility of hazardous reactions data is not available.
Conditions to avoid
Conditions to avoid data is not available.
Incompatible materials
Incompatible materials data is not available.
Hazardous decomposition products
Hazardous decomposition products data is not available.

Product name: GroE Mix

Product No.: PF004

Page 6 of 9
Revision date: Dec 1st, 2023
PF004 (US)Version 3

Section 11: Toxicological information
Information on toxicological effects
Acute toxicity
Acute toxicity (Oral)

Acute toxicity (Dermal)

Acute toxicity (Inhalation)

Irritant properties
Skin corrosion/irritation

Serious eye
damage/irritation

Classification of the product is not possible (Insufficient data
available or no data available).
Data for components of the product is not available.
Classification of the product is not possible (Insufficient data
available or no data available).
Data for components of the product is not available.
Classification of the product is not possible (Insufficient data
available or no data available).
Data for components of the product is not available.
Classification of the product is not possible (Insufficient data
available or no data available).
Data for components of the product is not available.
Classification of the product is not possible (Insufficient data
available or no data available).
Data for components of the product is not available.

Sensitization
Respiratory sensitization

Classification of the product is not possible (Insufficient data
available or no data available).
Data for components of the product is not available.
Skin sensitization
Classification of the product is not possible (Insufficient data
available or no data available).
Data for components of the product is not available.
Germ cell mutagenicity
Classification of the product is not possible (Insufficient data
available or no data available).
Data for components of the product is not available.
Carcinogenicity
Classification of the product is not possible (Insufficient data
available or no data available).
Data for components of the product is not available.
Reproductive toxicity
Classification of the product is not possible (Insufficient data
available or no data available).
Data for components of the product is not available.
Specific target organ toxicity (STOT)
STOT-single exposure
Classification of the product is not possible (Insufficient data
available or no data available).
Data for components of the product is not available.
STOT-repeated exposure
Classification of the product is not possible (Insufficient data
available or no data available).
Data for components of the product is not available.

Product name: GroE Mix

Product No.: PF004

Page 7 of 9
Revision date: Dec 1st, 2023
PF004 (US)Version 3

Aspiration hazard

Classification of the product is not possible (Insufficient data
available or no data available).
Data for components of the product is not available.

Section 12: Ecological information
Toxicity:
Aquatic toxicity
Classification of the product is not possible (Insufficient data
available or no data available).
Data for components of the product is not available.
Water solubility
Mineral F
256 g/100 ml (20°C) (ICSC, 2006)
Glycerin
miscible (ICSC, 2006)
Persistence and degradability:
Persistence and degradability data is not available.
Bioaccumulative potential:(Glycerin)
log Pow=-1.76 (ICSC, 2006)
Mobility in soil:
Mobility in soil data is not available.
Other adverse effects:
Ozone depleting chemical data is not available.
Section 13: Disposal considerations
Description of waste residues and information on their safe handling and methods of disposal,
including the disposal of any contaminated packaging
Waste treatment methods:
Dispose of contents/container in accordance with local/national regulation.
Do not dump into sewers, on the ground or into any body of water.
Contaminated packing:
Dispose of container after using the contents completely.

Product name: GroE Mix

Product No.: PF004

Page 8 of 9
Revision date: Dec 1st, 2023
PF004 (US)Version 3

Section 14: Transport information
UN number, UN CLASSUN No. or ID No.
UN Proper Shipping NameClass or division (Transport hazard class)Packing group

Not applicable.
Not applicable.
Not applicable.
Not applicable.

IMDG Code (International Maritime Dangerous Goods Regulations)Not applicable.
IATA Dangerous Goods Regulations
Not applicable.
Environmental hazards
MARPOL Annex III - Prevention of pollution by harmful substances
Marine pollutants (yes/no) : noSpecial precautions for user
Not applicable.
Maritime transport in bulk according to IMO instruments
This product is not intended to be carried in bulk.
Section 15: Regulatory information
Safety, health and environmental regulations/legislation specific for the substance or
mixtureU.S. Toxic Substances Control Act (TSCA) Inventory
Chemicals listed in TSCA Inventory
Buffer; Mineral F; Glycerin
Superfund Amendments and Reauthorizations Act (SARA), Title III
This product contains no chemicals subjected to reporting levels established by SARA Title III,
Section 313.
California proposition 65
This product does not contain any chemicals known to State of California to cause cancer,
birth defects, or any other reproductive harm.
Other regulatory information
We are not able to check up the regulatory information with regard to the substances in yourcountry or region, therefore, we request this matter would be filled by your responsibility.

Product name: GroE Mix

Product No.: PF004

Page 9 of 9
Revision date: Dec 1st, 2023
PF004 (US)Version 3

Section 16: Other information
GHS classification and labelling:
Not classified/Classification not possible
Reference Book:
Globally Harmonized System of classification and labelling of chemicals, UN
Recommendations on the TRANSPORT OF DANGEROUS GOODS 21th edit., 2019 UN
IMDG Code, 2018 Edition (Incorporating Amendment 39-18)
IATA Dangerous Goods Regulations (62nd Edition) 2021
2020 EMERGENCY RESPONSE GUIDEBOOK (US DOT)
2022 TLVs and BEIs. (ACGIH)
Supplier's data/information
Hazard Communication Standard - 2012 (29 CFR 1910.1200)
GESTIS-Stoffdatenbank
Pub Chem (OPEN CHEMISTRY DATABASE)[General Disclaimer]
The GHS classification data given here is based on current EU official data (Consolidated version of the CLP
Regulation published in 1.3.2022 and Commission delegated regulation (EU) 2021/849 (ATP17)) & US
Hazard Communication Standard - 2012.
This data sheet was created based on the information we currently have and may be revised according to
new information. In addition, the precautions apply only to normal handling, and in the case of special handling,please make adequate countermeasure to maintain your safety.

Product name: GroE Mix

Product No.: PF004

SAFETY DATA SHEET
Page 1 of 9
Revision date: Dec 1st, 2023
PF001-DB2 (US)Version 2

Section 1: Identification
Product identifier
Product name:Product code:

Dil. Buf. (Dilution Buffer)
PF001-DB2

Relevant identified uses of the substance or mixture and uses advised against
Relevant identified uses of the product:
This product is for research and development only.
Details of the supplier of the safety data sheet
Name:
Address:

GeneFrontier Corporation
SHARP Kashiwa Building 4F, 273-1
Kashiwa, Kashiwa-shi, Chiba 277-0005,
Japan+81-4-7137-6301+81-4-7132-7530
purefrex@genefrontier.com+81-4-7137-6301

Telephone number:Fax number:e-mail address:
Emergency telephone number:
Section 2: Hazard(s) identification

GHS classification and label elements of the product
Classification according to Hazard Communication Standard - 2012 (29 CFR 1910.1200)

Classification of the substance or mixture:

Not classified to GHS classification.

Labelling according to Hazard Communication Standard - 2012 (29 CFR 1910.1200)

Label elements:

No GHS label element.
No Signal word.

Section 3: Composition/information on ingredients
Mixture/Substance selection:

MixtureIngredient name
CAS No.
Content (%)
BufferTrade secret0.1 - 1
Mineral F
Trade secret0.1 - 2Glycerin
56-81-5
25 - 30
Note: The figures shown above are not the specifications of the product.
The specific chemical identity and/or exact percentage (concentration) of this composition
has been withheld as a trade secret.
The components not described in this component table are not listed in Table 3 of Annex VI
in EU CLP.
Product name: Dil. Buf. (Dilution Buffer)

Product No.: PF001-DB2

Page 2 of 9
Revision date: Dec 1st, 2023
PF001-DB2 (US)Version 2

Section 4: First-aid measures
Descriptions of first-aid measures
IF INHALEDIF ON SKIN (or hair)
IF IN EYESIF SWALLOWED

Remove person to fresh air and keep comfortable for breathing.
Call a POISON CENTER or doctor/physician if you feel unwell.
Wash with plenty of soap and water.
If skin irritation occurs: Get medical advice/attention.
Rinse cautiously with water for several minutes. Remove contactlenses, if present and easy to do. Continue rinsing.
If eye irritation persists: Get medical advice/attention.
Rinse mouth. Call a POISON CENTER or doctor/physician if you feelunwell.

Most important symptoms/effects, both acute and delayedSpecific information on symptom and effect are unknown.
Indication of any immediate medical attention and special treatment needed
Information on indication of any immediate medical attention and special treatment needed is
not available.
Section 5: Fire-fighting measures
Extinguishing media
Suitable extinguishing media:
Use appropriate extinguishing media suitable for surrounding facilities.
Unsuitable extinguishing media:
Unsuitable extinguishing media data is not available.
Specific hazards arising from the substance or mixture
No information available
Advice for firefighters
Specific fire-fighting measures:
Evacuate non-essential personnel to safe area.
Special protective equipment and precautions for fire-fighters:
Firefighters should wear self-contained breathing apparatus with full face peace operated
positive pressure mode.

Product name: Dil. Buf. (Dilution Buffer)

Product No.: PF001-DB2

Page 3 of 9
Revision date: Dec 1st, 2023
PF001-DB2 (US)Version 2

Section 6: Accidental release measures
Personal precautions, protective equipment and emergency procedures
Keep unauthorized personnel away. Wear proper protective equipment.
Environmental precautions
Prevent spills from entering sewers, watercourses, or low areas.
Do not wash away into sewers or waterway.
Methods and materials for containment and cleaning up
Absorb spill with inert material (dry sand, earth, et al), then place in a chemical waste container.
Section 7: Handling and storage
Precautions for safe handling
Preventive measures:
Avoid contact with skin.
Avoid contact with eyes.
Safety treatments:
Use personal protective equipment as required.
Advice on general occupational hygiene:
Do not get in eyes, on skin, or on clothing.
Do not eat, drink or smoke when using this product.
Wash hands thoroughly after handling.
Storage
Conditions for safe storage:
Keep container tightly closed.
Store at temperatures not exceeding designated temperature.
Storage temperature upper limit:-20 °C/ -4 °F
Container and packaging materials for safe handling:
No information available.

Product name: Dil. Buf. (Dilution Buffer)

Product No.: PF001-DB2

Page 4 of 9
Revision date: Dec 1st, 2023
PF001-DB2 (US)Version 2

Section 8: Exposure controls/personal protection
Control parameters
Adopted value
Adopted value in ACGIH is not available.
OSHA-PEL(Glycerin)
NIOSH-REL(Glycerin)

TWA: 5 mg/m3 (Respirable fraction)
TWA: 15 mg/m3 (Total dust)
See Appendix D

Exposure controls
Appropriate engineering controls:
Eye wash station should be available.
Washing facilities should be available.
Individual protection measures, such as personal protective equipment:
Hand protection

Eye protection
Skin and body protection

Wear protective gloves.
Recommended material(s): impermeable or chemical resistantrubber.
Wear safety glasses with side-shields or chemical safety
goggles.
Wear protective clothing.

Section 9: Physical and chemical properties
Information on basic physical and chemical properties
Physical state: Liquid
Colour: Clear
Odour: None
Odour threshold data is not available.
Melting point/Freezing point data is not available.
Boiling point or initial boiling point data is not available.
Boiling range data is not available.
Flammability (gases, liquids and solids): Non-flammable
Lower and upper explosion limit/flammability limit data is not available.
Flash point data is not available.
Auto-ignition temperature data is not available.
Decomposition temperature data is not available.
pH: 7-8
Kinematic viscosity data is not available.
Solubility
Solubility in water: Soluble
Solubility in solvent data is not available.
n-Octanol/water partition coefficient data is not available.
Vapor pressure data is not available.
Product name: Dil. Buf. (Dilution Buffer)

Product No.: PF001-DB2

Page 5 of 9
Revision date: Dec 1st, 2023
PF001-DB2 (US)Version 2

Density and/or relative density data is not available.
Relative vapor density (Air=1) data is not available.
Particle characteristics: Not applicable.
Evaporation rate data is not available.
Other information
No information available.
Section 10: Stability and reactivity
Reactivity
Reactivity data is not available.
Chemical stability
Stable under normal storage/handling conditions (see Section 7).
Possibility of hazardous reactions
Possibility of hazardous reactions data is not available.
Conditions to avoid
Conditions to avoid data is not available.
Incompatible materials
Incompatible materials data is not available.
Hazardous decomposition products
Hazardous decomposition products data is not available.

Product name: Dil. Buf. (Dilution Buffer)

Product No.: PF001-DB2

Page 6 of 9
Revision date: Dec 1st, 2023
PF001-DB2 (US)Version 2

Section 11: Toxicological information
Information on toxicological effects
Acute toxicity
Acute toxicity (Oral)

Acute toxicity (Dermal)

Acute toxicity (Inhalation)

Irritant properties
Skin corrosion/irritation

Serious eye
damage/irritation

Classification of the product is not possible (Insufficient data
available or no data available).
Data for components of the product is not available.
Classification of the product is not possible (Insufficient data
available or no data available).
Data for components of the product is not available.
Classification of the product is not possible (Insufficient data
available or no data available).
Data for components of the product is not available.
Classification of the product is not possible (Insufficient data
available or no data available).
Data for components of the product is not available.
Classification of the product is not possible (Insufficient data
available or no data available).
Data for components of the product is not available.

Sensitization
Respiratory sensitization

Classification of the product is not possible (Insufficient data
available or no data available).
Data for components of the product is not available.
Skin sensitization
Classification of the product is not possible (Insufficient data
available or no data available).
Data for components of the product is not available.
Germ cell mutagenicity
Classification of the product is not possible (Insufficient data
available or no data available).
Data for components of the product is not available.
Carcinogenicity
Classification of the product is not possible (Insufficient data
available or no data available).
Data for components of the product is not available.
Reproductive toxicity
Classification of the product is not possible (Insufficient data
available or no data available).
Data for components of the product is not available.
Specific target organ toxicity (STOT)
STOT-single exposure
Classification of the product is not possible (Insufficient data
available or no data available).
Data for components of the product is not available.
STOT-repeated exposure
Classification of the product is not possible (Insufficient data
available or no data available).
Data for components of the product is not available.

Product name: Dil. Buf. (Dilution Buffer)

Product No.: PF001-DB2

Page 7 of 9
Revision date: Dec 1st, 2023
PF001-DB2 (US)Version 2

Aspiration hazard

Classification of the product is not possible (Insufficient data
available or no data available).
Data for components of the product is not available.

Section 12: Ecological information
Toxicity:
Aquatic toxicity
Classification of the product is not possible (Insufficient data
available or no data available).
Data for components of the product is not available.
Water solubility
Mineral F
256 g/100 ml (20°C) (ICSC, 2006)
Glycerin
miscible (ICSC, 2006)
Persistence and degradability:
Persistence and degradability data is not available.
Bioaccumulative potential:(Glycerin)
log Pow=-1.76 (ICSC, 2006)
Mobility in soil:
Mobility in soil data is not available.
Other adverse effects:
Ozone depleting chemical data is not available.
Section 13: Disposal considerations
Description of waste residues and information on their safe handling and methods of disposal,
including the disposal of any contaminated packaging
Waste treatment methods:
Dispose of contents/container in accordance with local/national regulation.
Do not dump into sewers, on the ground or into any body of water.
Contaminated packing:
Dispose of container after using the contents completely.

Product name: Dil. Buf. (Dilution Buffer)

Product No.: PF001-DB2

Page 8 of 9
Revision date: Dec 1st, 2023
PF001-DB2 (US)Version 2

Section 14: Transport information
UN number, UN CLASSUN No. or ID No.
UN Proper Shipping NameClass or division (Transport hazard class)Packing group

Not applicable.
Not applicable.
Not applicable.
Not applicable.

IMDG Code (International Maritime Dangerous Goods Regulations)Not applicable.
IATA Dangerous Goods Regulations
Not applicable.
Environmental hazards
MARPOL Annex III - Prevention of pollution by harmful substances
Marine pollutants (yes/no) : noSpecial precautions for user
Not applicable.
Maritime transport in bulk according to IMO instruments
This product is not intended to be carried in bulk.
Section 15: Regulatory information
Safety, health and environmental regulations/legislation specific for the substance or
mixtureU.S. Toxic Substances Control Act (TSCA) Inventory
Chemicals listed in TSCA Inventory
Buffer; Mineral F; Glycerin
Superfund Amendments and Reauthorizations Act (SARA), Title III
This product contains no chemicals subjected to reporting levels established by SARA Title III,
Section 313.
California proposition 65
This product does not contain any chemicals known to State of California to cause cancer,
birth defects, or any other reproductive harm.
Other regulatory information
We are not able to check up the regulatory information with regard to the substances in yourcountry or region, therefore, we request this matter would be filled by your responsibility.

Product name: Dil. Buf. (Dilution Buffer)

Product No.: PF001-DB2

Page 9 of 9
Revision date: Dec 1st, 2023
PF001-DB2 (US)Version 2

Section 16: Other information
GHS classification and labelling:
Not classified/Classification not possible
Reference Book:
Globally Harmonized System of classification and labelling of chemicals, UN
Recommendations on the TRANSPORT OF DANGEROUS GOODS 21th edit., 2019 UN
IMDG Code, 2018 Edition (Incorporating Amendment 39-18)
IATA Dangerous Goods Regulations (62nd Edition) 2021
2020 EMERGENCY RESPONSE GUIDEBOOK (US DOT)
2022 TLVs and BEIs. (ACGIH)
Supplier's data/information
Hazard Communication Standard - 2012 (29 CFR 1910.1200)
GESTIS-Stoffdatenbank
Pub Chem (OPEN CHEMISTRY DATABASE)[General Disclaimer]
The GHS classification data given here is based on current EU official data (Consolidated version of the CLP
Regulation published in 1.3.2022 and Commission delegated regulation (EU) 2021/849 (ATP17)) & US
Hazard Communication Standard - 2012.
This data sheet was created based on the information we currently have and may be revised according to
new information. In addition, the precautions apply only to normal handling, and in the case of special handling,please make adequate countermeasure to maintain your safety.

Product name: Dil. Buf. (Dilution Buffer)

Product No.: PF001-DB2