長崎大学医学部業績集 ２．研究業績

解剖学第三Ａ

欧文Ａ‑ａ
１．Imaizumi Y, Murota H, Kanda S, Hishikawa Y, Koji T, Taguchi T, Tanaka Y, Yamada Y, Ikeda S, Kohno
T, Yamamoto K, Mori N, Tomonaga M , M atsuyama T: Expression of the c‑Met proto‑oncogene and its
possible involvement in liver invasion in adult T‑cell leukemia. Clin Cancer Res 9 (1):181‑187, 2003 ◎２．Tamura K,Oka T,Ohsawa K,Koji T,Watanabe Y,Katamine S,Sato H,Ayabe H:Allogeneic cell stimulation
enhances cytomegalovirus replication in the early period of primary infection in an experimental rat model.
J Heart Lung Transplant 22(4):452‑459, 2003 ○◎☆
３．Yamamoto‑Fukuda T, Aoki D, Hishikawa Y, Kobayashi T, Takahashi H, Koji T:Possible involvement ofkeratinocyte growth factor and its receptor in enhanced epithelial‑cell proliferation and acquired recurrenceof middle‑ear cholesteatoma. Lab Invest 83(1):123‑136, 2003 ○◎４．Tsurusaki T,Aoki D,Kanetake H,Inoue S,Muramatsu M ,Hishikawa Y,Koji T:Zone‑dependent expressionof estrogen receptors α and β in human benign prostatic hyperplasia. J Clin Endocrinol M etab 88(3):1333‑1340, 2003 ◎５．Okada K,Nakashima M ,Komuta K,Hashimoto S,Okudaira S,Baba N,Hishikawa Y,Koji T,Kanematsu T,Watanabe T:Expression of tumor‑associated membrane antigen,RCAS1,in human colorectal carcinomas andpossible role in apoptosis of tumor‑infiltrating lymphocytes. Modern Pathol 16(7):679 ‑685, 2003 ◎６．Nishino T, Miyazaki M , Abe K, Furusu A, M ishima Y, Harada T, Ozono Y, Koji T, Kohno, S:Antisense
oligonucleotides against collagen‑binding stress protein HSP47 suppress peritoneal fibrosis in rats.Kidney Int64(3):887‑896, 2003 ○☆◎７．Mishima Y, Miyazaki M, Abe K, Ozono Y, Shioshita K, Xia Z, Harada T, Taguchi T, Koji T, Kohno S:
Enhanced expression of heat shock protein 47 in rat model of peritoneal fibrosis. Perit Dial Int 23(1):14‑22,
2003 ○☆◎
８．Ashizawa M, Miyazaki M , Abe K, Furusu A, Isomoto H, Harada T, Ozono Y, Sakai H, Koji T, Kohno S:
Detection of nuclear facator‑kB in IgA nephropathy using southwestern histochemistry. Am J Kidney Dis 42(1):76‑86, 2003 ○◎９．Miyazaki M, Nishino T, Abe K, Furusu A, Koji T, Kohno S: Regulation of renal extracellular matrix
metabolism. Contrib Nephrol 139:141‑155, 2003 ◎10．Izumi S, Shin M, Takano K, Nakane PK,Koji T:Differential analysis of active and inactive genes in humanneutrophils by chromosomal in situ hybridization. Acta Histochem Cytochem 36(4):325‑330, 2003 ◎11．Nonaka M I,Hishikawa Y,Moriyama N,Koji T,Ogata RT,Kudo A,Kawakami H,Nonaka M :Complement
C4b‑binding protein as a novel murine epididymal secretory protein. Biol Reprod 69 (6):1931‑1939, 2003 ☆
◎12．Nakashima K,Kawakami A,Hida A,Yamasaki S,Nakamura H,Kamachi M,Miyashita T,Tanaka F,IzumiY, Tamai M, Ida H, Furuyama M, Koji T, Nakamura T, M igita K, Origuchi T, Eguchi K: Protection of
mitochondrial perturbation by human T‑lymphotropic virus type 1 tax through induction of Bcl‑xL expression. J Lab Clin Med 142(5):341‑347, 2003 ○◎13．Ohara H, Isomoto H, Wen CY, Ejima C, Murata M, Miyazaki M , Takeshita F, Mizuta Y, Murata I, Koji T,Nagura H,Kohno S:Expression of mucosal addressin cell adhesion molecule 1 on vessel endothelium ofgastricmucosa in patients with nodular gastritis. World J Gastroenterol 9 (12):2701‑2705, 2003 ○◎14．Ueda S, Yamanoi A, Hishikawa Y, Dhar DK, Tachibana M , Nagasue N:Transforming growth factor‑β 1
released from the spleen exerts a growth inhibitory effect on liver regeneration in rats.Lab Invest 83(11):1595‑1603, 2003 ○☆◎15．Ejima K, Layne MD, Carvajal IM , Kritek PA, Baron RM , Chen YH, Saal J, Levy BD, Yet SF, Perrella M A.
Cyclooxygenase‑2 deficient mice are resistant to endotoxin‑induced inflammation and death.FASEB J 17(10):1325‑1327, 2003 ☆◎16．Shibata E, Nnri H, Ejima K, Araki M, Fukuda J, Yoshimura K, Toki N, Ikeda M , Kashimura M :Peroxiredoxin III/SP‑22 in the mitochondria of human pre‑eclamptic placentae.Placenta 24(6):698‑705,2003◎17．Chen YH , Layne M D, Chung SW, Ejma K, Baron RM, Yet SF, Perrella MA. Elk‑3 Is a transcriptional
repressor of nitric oxide synthase 2. J Biol Chem 278(41):39572‑39577, 2003 ☆◎18．Watanabe I,Liu J,Atsuta M,Okabe T:Effect of welding method on joint strength of laser‑welded gold alloy.
Am J Dent 16(4):231‑234, 2003

13

19．Watanabe I,Atsuta M,Liu J:Mechanical retention of low‑fusing porcelain to cast titanium.Prosthodont Res
Pract 2(1):43‑48, 2003

Ａ‑ｂ
１．Koji T,Hishikawa Y:Germ cell apoptosis and its molecular trigger in mouse testes.Arch Histol Cytol 66(1):
1‑16, 2003 (Review)
２．Hishikawa Y,Damavandi E,Izumi S,Koji T:Molecular histochemical analysis of estrogen receptor αand β
expressions in the mouse ovary:In situ hybridization and Southwestern histochemistry.M ed Electron Microsc
36(2):67‑73, 2003 (Review)
３．Abe K, Miyaziki M, Yoshio Y, Furusu A, Harada T, Sugaya T, Ozono Y, Koji T, Kohno S:Importance ofangiotensin
type 1 receptor in bone marrow derived cell in the progression of peritoneal fibrosis. J Amer
Soc Nephrol 14:36A, 2003
４．Kinoshita T, Abe K, M iyazaki M , Yoshio Y, Obata Y, Harada T, Ozono Y, Koji T, Kohno S:Expression ofaldosterone synthase gene in IgA nephropathy (IgAN). J Amer Soc Nephrol 14:376A, 2003
５．Hayashi Y,Miyazaki M,Abe K,Yoshio Y,Harada T,Ozono Y,Sugaya T,Koji T,Kohno S:Possible role of(A ) in glomerular remodeling in mouse mesangial proliferative glomerulonephritis model.Jangiotensin
Amer Soc Nephrol 14:412A, 2003
６．Yoshio Y, Miyazaki M, Abe K, Miyazaki M , Jinnouchi C, Funakoshi S, Harada T, Ozono Y, Koji T, Kohno
S:Roles of bone marrow derived cells in experimental mouse peritoneal fibrosis.J Amer Soc Nephrol 14:477A,
2003
７．Jinnouchi C,Miyazaki M,Abe K,Yoshio Y,Harada T,Niwa M ,Koji T,Kohno S:Involvement of macrophage
infilration in the development of renal injury in stroke‑prone spontaneously hypertensive rats (SHRSP). JAmer Soc Nephrol 144:640A, 2003
８．Baba N, Watanabe I, Liu J, Atsuta M:M echanical property of laser‑welded Ag‑Pd‑Au alloy. J Dent Res 82(Special Issue B):B‑130, #0938, 2003

Ａ‑ｃ
１．Koji T,Izumi S,Hishikawa Y:Molecular histochemistry of rRNAs by nonradioactive in situ hibyridization atlight‑ and electron‑microscopic Levels.Advancement of Life Science,Edited Kojun Setsu and Cheng‑HsiungRoan, AMVO PUBLISHING COM PANY, Taipei Taiwan. 141‑146, 2003
２．Hishikawa Y,Izumi S,Koji T:Southwestern histochemical analysis of estrogen responsive element in paraffin‑embedded tissue sections of mouse ovary. Advancement of Life Science, Edited Kojun Setsu and Cheng‑Hsiung Roan, AMVO PUBLISHING COM PANY, Taipei Taiwan. 147‑152, 2003
３．Izumi S, Takano K, Hishikawa Y, Koji T:In situ hybridization of prolactin mRNA in rat pituitary sections:Backscattered electron mode analysis using light microscopic specimen on glass slides.Advancement of LifeScience,Edited Kojun Setsu and Cheng‑Hsiung Roan,AMVO PUBLISHING COMPANY,Taipei Taiwan.153‑158, 2003
４．An S,Hishikawa Y,Koji T:Induction of apoptosis in the crypts of rat small intestine by ischemia‑reperfusion.
Advancement of Life Science, Edited Kojun Setsu and Cheng‑Hsiung Roan, AMVO PUBLISHING COM PANY, Taipei Taiwan. 159 ‑164, 2003

Ｂ邦

文Ｂ‑ｂ
１．小路武彦：分子組織細胞化学：遺伝子発現をみる．Kyushu Branch Jap Soc Clin Cytol 33 :1‑8、2003
２．菱川善隆、小路武彦：In situ hybridization によるゲノム転写物の局在証明と定量的解析． ニューサイエンス社、細胞35：489‑493、2003

Ｂ‑ｃ
１．小路武彦：国立大学法人化への燕雀の杞憂． 学術の動向 8(2)：22‑25、2003
２．小路武彦：2002年12月のミャンマー：乾季での驚き−雨が降る−． 長崎県 JICA 派遣専門家連絡会会報

142：4、

長崎大学医学部業績集 ２．研究業績
2003
３．小路武彦（分担執筆）：「医学書院医学大辞典」． （伊藤正男、井村裕夫、高久史麿編）、医学書院、東京、2003
４．小路武彦：遺伝子組織化学総論［組織細胞化学2003］． （日本組織細胞化学会編）、学際企画、東京、115‑126、2003

Ｂ‑ｄ１．小路武彦：生殖細胞アポトーシス誘導プログラムの多様性と一様性． 平成12年度〜平成14年度科学研究費補助金（基盤研究（B）（2））研究成果報告書、2003

原著論文数一覧
Ａ‑ａ2003

Ａ‑ｂ Ａ‑ｃ19８４Ａ‑ｄ合計

SCI

B‑ａB‑ｂB‑ｃB‑ｄ合計

総 計

０3118０241738合 計

総 計

2328

学会発表数一覧
Ａ‑ａ2003

Ａ‑ｂシンポジウム

学会

0５0合計
５Ｂ‑ａ５B‑ｂシンポジウム

学会

０18

原著論文総数に係る教官生産係数一覧
欧文論文総数 教官生産係数 ＳＣＩ掲載論文(論文総数)
2003

0.674

教官生産係数（欧文論文) 欧文論文総数 （ＳＣＩ掲載論文)
7.75

0.581

4.5

Impact factor 値一覧
2003

Impact factor

１教官当たり Impact factor

論文当たり Impact factor

67.57616.8943.754

15