specifications

bulletin 6092

S1000™ Thermal Cycler
Bio-Rad’s S1000 thermal cycler offers premium thermalperformance, whether operated as a stand-alone instrument orconnected to a C1000 Touch™ thermal cycler as part of a larger
multi-bay configuration.
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
Innovativeengineering delivers exceptional performanceand flexibility
Choiceof interchangeable reaction modules includes
gradient-enabled dual 48/48-well fast, gradient-enabled
96-well fast, gradient-enabled 96–deep well,and gradient-enabled 384-well reaction modules
Patented
O-ring hermetic seal* and reduced-mass sample
block** design provide quick time-to-target temperature forfast protocol run times
Fully adjustable heated lid accommodates a broad range of vessels
Optional
PC control and networking capability for up to 32
systems enable the ultimate in high throughput

Specifications
Thermal Cycler		
Input power
Up to 700 W, maximum

Temperature control modes

Calculated and block

Frequency

50–60 Hz, single phase

PCR license

Yes

Display

LCD

Programming options

Text basedPorts

4 USB A, 1 USB B

PC compatibility

Fuses

Two 10 A, 250 V, 5 x 20 mm		Windows XP or higher with C1000™
or C1000 Touch thermal cycler

Memory	>1,000 typical programs onboard

Instant incubation

Yes

Dimensions (W x D x H)

33 x 46 x 20 cm (13 x 18 x 8")		

Weight10 kg (23 lb)

Reaction Modules
Sample capacity		

96-Well Fast
96 x 0.2 ml tubes
or 1 x 96-well plate

96–Deep Well
96 x 0.2 ml tubes, 48 x 0.5 ml tubes,
or 1 x 96-well plate

Dual 48/48 Fast
2 x 48 x 0.2 ml tubes
or 2 x 48-well plates

384-Well1 x 384-well plate

Maximum ramp rate

5°C/sec

2.5°C/sec

4°C/sec

2.5°C/sec

Average ramp rate

3.3°C/sec

2°C/sec

3°C/sec

2°C/sec

Temperature range

0–100°C

0–100°C

0–100°C

0–100°C

Temperature accuracy		±0.2°C of programmed
target at 90°C

±0.2°C of programmed
target at 90°C

±0.2°C of programmed
target at 90°C

±0.2°C of programmed
target at 90°C

Temperature uniformity				±0.4°C well-to-wellwithin 10 sec ofarrival at 90°C

±0.4°C well-to-wellwithin 10 sec ofarrival at 90°C

±0.4°C well-to-wellwithin 10 sec ofarrival at 90°C

±0.4°C well-to-wellwithin 10 sec ofarrival at 90°C

Gradient capability

Yes

Yes

Yes

Yes

Gradient
Gradient range

30–100°C

Temperature differential range

1–24°C* U.S. patent 7,051,536.
** U.S. patent 7,632,464.

12-1418_S1000_Spec_sheet_FINAL.indd 1

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90Temperature, °C

8580

C1000 Touch Thermal Cycler
75706560

S1000 Thermal Cyclers

55020

4060

80

100120140160180200Time, sec
Rapid arrival at target temperature and superior uniformity. Graph shows
temperature measured by probes in 15 wells across the sample block of a 1000-series
thermal cycler. Traces are nearly indistinguishable due to the tight uniformity. Notethe consistent ramp rate throughout heating and cooling. 1000-series thermal cyclers
exhibit high average ramp rates, rapid settling time, and tight thermal uniformity
throughout the ramp, resulting in rapid arrival at target temperature and enabling faster
protocol run times.

Expansion capabilities provide the ultimate in high throughput.
Up to three S1000 thermal cyclers can be connected to a C1000
Touch cycler to operate as a four-bay instrument. With the additionof a PC and CFX Manager™ software version 2.1 or higher, up to 32
instruments can be operated in tandem.

Ordering Information
Catalog #Description

184-2000
S1000 Thermal Cycler Chassis, includes power cord; does not include reaction module
185-2148	
S1000 Thermal Cycler with Dual 48/48 Fast Reaction Module, includes S1000 thermal cycler chassis, dual 48/48 fast reaction module
185-2196
S1000 Thermal Cycler with 96-Well Fast Reaction Module, includes S1000 thermal cycler chassis, 96-well fast reaction module
185-2197	S1000 Thermal Cycler with 96–Deep Well Reaction Module, includes S1000 thermal cycler chassis, 96–deep well reaction module
185-2138	S1000 Thermal Cycler with 384-Well Reaction Module, includes S1000 thermal cycler chassis, 384-well reaction module184-1100
C1000 Touch Thermal Cycler Chassis, includes USB flash drive, power cord; does not include reaction module
184-0148
Dual 48/48 Fast Reaction Module, independent dual 48-well reaction module, fits C1000, C1000 Touch, and S1000 thermal cyclers, gradient enabled
184-0196
9 6-Well Fast Reaction Module, fits C1000, C1000 Touch, and S1000 thermal cyclers, gradient enabled
184-0197
96–Deep Well Reaction Module, fits C1000, C1000 Touch, and S1000 thermal cyclers, gradient enabled
184-0138
3 84-Well Reaction Module, fits C1000, C1000 Touch, and S1000 thermal cyclers, gradient enabled
170-8870
iTaq™ DNA Polymerase, 5 U/μl, includes 250 U polymerase, 1.25 ml 10x PCR buffer (200 mM Tris-HCI, pH 8.4, 500 mM KCI),
1.25 ml 50 mM MgCl2 solution
170-8891
iScript™ cDNA Synthesis Kit, 100 x 20 μl reactions, includes 5x iScript reaction mix, iScript reverse transcriptase, nuclease-free water172-5301
iProof™ High-Fidelity DNA Polymerase, 2 U/μl, 100 U, includes 5x reaction buffers, MgCl2 solution, DMSO
172-5310
iProof HF Master Mix, 100 x 50 μl reactions, includes 2x master mix (0.04 U/μl), DMSO (for highest fidelity with most templates)
TWI-0201
PCR Tubes with Domed Caps (0.2 ml), clear, 1,000
TBC-08028-Tube Strips and Domed Cap Strips (0.2 ml), clear, 20 bags of 12 x 8-tube strips and 12 x 8-cap strips (1,920 PCR tubes and 1,920 caps)
MSB-1001
Microseal® 'B' Adhesive Seals, optically clear, 100
TCS-0801
Domed 8-Cap Strips, for 0.2 ml PCR tubes and plates, clear, 120
MLP-9601
Multiplate™ 96-Well Unskirted PCR Plates, clear, 25 plates
Windows is a trademark of Microsoft Corporation.
Notice regarding Bio-Rad thermal cyclers and real-time systems:
Purchase of this instrument conveys a limited non-transferable immunity from suit for the purchaser’s own internal research and development and for use in humanin vitro diagnostics and all other applied fields under U.S. Patent Number 5,475,610 (Claims 1, 44, 158, 160–163, and 167 only), or corresponding claims in its
non-U.S. counterpart, owned by Applera Corporation. No right is conveyed expressly, by implication, or by estoppel under any other patent claim, such as claims
to apparatus, reagents, kits, or methods such as 5' nuclease methods. Further information on purchasing licenses may be obtained by contacting the Director ofLicensing, Applied Biosystems, 850 Lincoln Centre Drive, Foster City, California 94404, USA.
Bio-Rad’s thermal cyclers and real-time thermal cyclers are covered by one or more of the following U.S. patents or their foreign counterparts owned by Eppendorf
AG: U.S. Patent Numbers 6,767,512 and 7,074,367.
Practice of the patented 5' Nuclease Process requires a license from Applied Biosystems. The purchase of these products includes an immunity from suit underpatents specified in the product insert to use only the amount purchased for the purchaser’s own internal research when used with the separate purchaseof Licensed Probe. No other patent rights are conveyed expressly, by implication, or by estoppel. Further information on purchasing licenses may beobtained from the Director of Licensing, Applied Biosystems, 850 Lincoln Centre Drive, Foster City, California 94404, USA.

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