Plenary Lecture 2【Room A】1F, Conference Center

March 29, Fri., 8:50-9:50

Chair: Makoto Tominaga (National Institute for Physiological Sciences, Japan)

Natural Products as Probes of the Pain Pathway:
PL2	
From Physiology to Atomic StructureDavid Julius
Department of Biochemistry and Biophysics, The University of California,
San Francisco, USA

Special Lecture1

The Susumu Hagiwara Memorial Lecture

March 29, Fri., 17:20-18:10【Room A】1F, Conference Center

Chair: Atsushi Nambu (National Institute for Physiologocal Sciences, Japan)

retrospection in the primate

Yasushi Miyashita
RIKEN Center for Brain Science, Japan

Special Lecture2
March 29, Fri., 17:20-18:10【Room B】3F, Conference Center

Chair: Mariko Omatsu-Kambe (Shiga University of Medical Science, Japan)

SL2 Signaling by Mitochondrial Flashes

Heping (Peace) Cheng
Peking University, China

DAY 2

Beyond memory circuit: Origins of metamemory andSL1	Special Lecture3【Room C】3F, Conference Center

March 29, Fri., 17:20-18:10

Chair: Michisuke Yuzaki (Keio University School of Medicine, Japan)

Tentonin 3, a Mechanosensitive Channel withSL3	Baroreceptor Function

Uhtaek Oh
Brain Science Institute, KIST, Korea

Special Lecture4
March 29, Fri., 17:20-18:10【Room D】4F, Conference Center

Chair: Noriyuki Koibuchi (Gunma University Graduate School of Medicine, Japan)

Finding Instructional Balance Using the Educational
SL4	
Triangle

Robert Graham Carroll
Office of Medical Education, Brody School of
Medicine,
East Carolina University, USASymposium1 (Local Organizing Committee Symposium)【Room A】1F, Conference Center

March 29, Fri., 10:00-12:00
S1

Molecular mechanisms of aging(Co-organized by the Japanese Society of Anti-Aging Medicine)

Shigeo Horie (Juntendo University, Graduate School of Medicine, Japan)

S1-1

The FGF-Klotho endocrine system and aging
Makoto Kuro-oDivision of Anti-aging Medicine, Center for Molecular Medicine, Jichi Medical University,
Japan

S1-2

The roles and mechanisms of SASP in aging and cancer
Eiji Hara1,2)

1
Research Institute for Microbial Diseases, Osaka University, Japan, 2Immunology
Frontier Research Center, Osaka University, Japan

S1-3

Necroptosis promotes the Aging of the Male Reproductive System inMice and Man
Xiaodong Wang, Dianrong Li, Lingjun Meng, Tao Xu, Yaning Su,
Xiao Liu, Zhiyuan Zhang
National Institute of Biological Sciences, China

S1-4

Significance of NAD/Sirtuins in Non-Communicable Diseases (NCD)and Metabo-Aging
Hiroshi Itoh

Department of Endocrinology, Metabolism and Nephrology School of Medicine, Keio
University, JapanDAY 2

Chairs: Shohei Mitani (Tokyo Women’s Medical University, Japan)

Symposium2 (Local Organizing Committee Symposium)
March 29, Fri., 10:00-12:00
S2【Room B】3F, Conference Center

Thermal biology: A new world of life science(whole day symposium) part I(Co-organized by Grant-in-Aid for Scientific Reserch on Innovative Areas‘Thermal Biology’ of MEXT, Japan)

Chairs: Makoto Tominaga (National Institute for Physiological Sciences, Japan)

Masao Doi (Kyoto University, Japan)

S2-1

Physiological Significance of Thermosensitive TRP Channels
Makoto Tominaga1,2)

1
Division of Cell Signaling, National Institute for Physiological Sciences, Japan, 2Thermal
Biology Group, Exploratory Research Center on Life and Living Systems, Japan

S2-2

Imaging intracellular temperature unveils thermal signaling in single
cells
Kohki Okabe1,2)1Graduate School of Pharmaceutical Sciences, University of Tokyo, Japan, 2PRESTO, JST,
Japan

S2-3

Transient intracellular acidification regulates the core transcriptional
heat shock responseDavid Allan Drummond1), Catherine G Triandafillou2),
Christopher D Katanski1), Aaron R Dinner3)

Department of Biochemistry and Molecular Biology, The University of Chicago, USA,
Graduate Program in Biophysical Sciences, The University of Chicago, USA, 3Departmentof Chemistry and the James Franck Institute, The University of Chicago, USA
1
2

Part II starts from 15:10 at the same room.

Symposium3 (International Scientific Program Committee Symposium)
March 29, Fri., 10:00-12:00
S3【Room C】3F, Conference Center

Gastrointestinal microbiome and immunophysiology (CPS, Taiwan)

Shinji Fukuda (Institute for Advanced Biosciences, Keio University, Japan)

S3-1

Metabologenomic approach reveals the function of gut microbiota inhealth and disease
Shinji Fukuda1,2,3,4,5)

1
Institute for Advanced Biosciences, Keio University, Japan, 2PRESTO, Japan Science andTechnology Agency (JST), Japan, 3Kanagawa Institute of Industrial Science andTechnology (KISTEC-KAST), Japan, 4Transborder Medical Research Center, University ofTsukuba, Japan, 5Metabologenomics, Inc., Japan

S3-2

Pathophysiology of the gut microbiota in digestive diseases
Sunny Hei Wong1,2,3)

Department of Medicine and Therapeutics, Faculty of Medicine, The Chinese Universityof Hong Kong, Hong Kong, 2Li Ka Shing Institute of Health Sciences, The Chinese
University of Hong Kong, Hong Kong, 3Institute of Digestive Disease, The Chinese
University of Hong Kong, Hong Kong1

S3-3

Microbiota dysbiosis and immune abnormality in colorectal
carcinogenesis
Linda Chia-Hui Yu

National Taiwan University College of Medicine, Taiwan

S3-4

Microbiota biofilm dysbiosis and pathobiont release induced byenteropathogens or in IBD
Andre G. Buret

Biological Sciences, Inflammation Research Network, Canada

DAY 2

Chairs: Linda Chia-Hui Yu (National Taiwan University College of Medicine, Taiwan)

Symposium4 (Local Organizing Committee Symposium)
March 29, Fri., 10:00-12:00
S4【Room D】4F, Conference Center

Teaching physiology; International perspectives(whole day symposium) part I

Chair: Mei-Ling Tsai (National Cheng Kung University, Taiwan)
S4-1

Role that the ‘step-by-step study of life sciences’ may play in healthrelated higher education
Masato Shibuya1,3), Kaname Higuchi1,3), Toshikazu Yamashita2,3)

1
Dept Physiol, Kagawa Nutrition Jr Col, Japan, 2Dept Applied Physiol, Kagawa Nutrition
Univ, Japan, 3Life Science Education Sharing Group, Japan

S4-2

Team-based Learning - the backbone of medical education in
LKCMedicine
Fabian C.L. Lim

Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore

S4-3

The role of Indonesian Physiology Society to improve physiology
teaching in Indonesia
Adrianta Surjadhana

Department of Physiology,Ciputra University, Indonesia

S4-4

Ethical Teaching: A Dilemma in Medical Education
Arif Siddiqui1), Kusal Kanti Das2)
1

Barrett Hodgson University, Pakistan, 2BLDE University, India

Part II starts from 15:10 at the same room.

Symposium5【Room E】4F, Conference Center

March 29, Fri., 10:00-12:00
S5

Masanari Umemura (Cardiovascular Research Institute, Yokohama City University
Graduate School of Medicine, Japan)

Co-Chair: Lin Hai Kurahara (School of Medicine, Fukuoka-University, Japan)
S5-1

Calcium-sensing receptor and PDGF signals on vascular remodelingin pulmonary hypertension
Aya Yamamura, Motohiko Sato

Department of Physiology, Aichi Medical University, Japan

S5-2

Relationship between Physical Stimulus and Cardiac RemodelingMasanari Umemura, Masatoshi Narikawa, Ryo Tanaka, Yoshihiro Ishikawa
Cardiovascular Research Institute, Yokohama City University Graduate School of
Medicine, Japan

S5-3

The Neuro-Mechanical unloading limits the infarct size and prevents
subsequent heart failure
Keita Saku

Department of Advanced Risk Stratification for Cardiovascular Disease, Center for
Disruptive Cardiovascular Medicine, Kyushu University, Japan

S5-4

Long noncoding RNAs: emerging players in cardiac electrical andstructural remodeling
Yong Zhang, Ying Zhang, Lei Jiao, Lina Xuan, Xin Liu, Baofeng Yang
Department of Pharmacology, Harbin Medical University, China

DAY 2

Chair:New Translational Insights on Cardiopulmonary RemodelingSymposium6
March 29, Fri., 10:00-12:00
S6【Room F】5F, Conference Center

Facilitation of Recovery of Motor Function After Paralysis(Co-sponsored by Uno Hospital)

Chair:
Yukio Nishimura (Tokyo Metropolitan Institute of Medical Science, Japan)
Co-Chair: Takuya Takahashi (Yokohama City University, Japan)
S6-1

CRMP2 Binding Compound, Edonerpic Maleate, Accelerates Motor
Function Recovery from Brain Damage
Takuya Takahashi

Department of Physiology Yokohama City University, Japan

S6-2

Bypassing damaged neural pathways via a neural interface
Yukio Nishimura

Neural Prosthesis Project, Tokyo Metropolitan Institute of Medical Science, Japan

S6-3

Repetitive facilitation exercise with non-invasive stimulation forrecovery of hemiplegia
Seiji Etoh, Megumi Shimodozono, Kazumi Kawahira

Department of Rehabilitation and Physical Medicine, Kagoshima University Graduate
School of Medical and Dental Sciences, Japan

S6-4

Predicting motor outcomes for individual patients after stroke
Marie-Claire Smith, Cathy Maree Stinear

Department of Medicine, University of Auckland, New ZealandSymposium7 (International Scientific Program Committee Symposium)
March 29, Fri., 10:00-12:00
S7【Room G】5F, Conference Center

From synaptic and network plasticity to behavior (CAPS, China)

Tian-Le Xu (Shanghai Jiao Tong University School of Medicine, China)

S7-1

Fear extinction requires ASIC1a-dependent regulation of hippocampal-prefrontal correlates
Tian-Le Xu, Qin Wang, Qi Wang, Wei-Guang Li

Collaborative Innovation Center for Brain Science, Department of Anatomy andPhysiology, Shanghai Jiao Tong University School of Medicine, China

S7-2

How does social conflict affect the synaptic plasticity in habenulointerpeduncular pathway?
Hitoshi Okamoto

Lab. for Neural Circuit Dynamics of Decision Making, RIKEN Center for Brain Science,
Japan

S7-3

Postnatal refinement of circuit plasticity for spatial navigation
Ying-Shing Chan, Kenneth Lap-Kei Wu, Wei Shi, Qiu-Fen Jiang,
Chun-Wai Ma, Daisy Kwok-Yan ShumSchool of Biomedical Sciences, Li Ka Shing Faculty of Medicine, The University of Hong
Kong, Hong Kong

S7-4

Behavioural Impact of Synaptic Kainate Receptor Protein Levels
Juan Lerma

Instituto de Neurociencias CSIC-UMH, San Juan de Alicante, Spain

DAY 2

Chairs: Ying-Shing Chan (The University of Hong Kong, Hong Kong)

Symposium8
March 29, Fri., 10:00-12:00
S8【Room H】5F, Conference Center

Biophysical mechanisms underlying nano-vibrations of the sensory
epithelium in hearing organs(Co-sponsored by the Society for Promotion of International Oto-Rhino-Laryngology)

Chair:
Hiroshi Hibino (Niigata University School of Medicine, Japan)
Co-Chair: Tobias Reichenbach (Imperial College London, UK)
S8-1

Detection of an atypical motion in cochlear sensory epithelium
Takeru Ota1,2), Fumiaki Nin1,2), Samuel Choi2,3), Hiroshi Hibino1,2)

Department of Molecular Physiology, Niigata University School of Medicine, Japan,
AMED-CREST, AMED, Japan, 3Department of Electrical and Electronics Engineering,
Niigata University, Japan

1
2

S8-2

Sensory tissue motion and hair cell responses in the base of the gerbil cochlea
Elizabeth Sue Olson1), Clark Elliott Strimbu4), Yi Wang2), Nathan C Lin3),
Elika Fallah2)

Departments of Otolaryngology and Biomedical Engineering, Columbia University,
USA, 2Department of Biomedical Engineering, Columbia University, USA, 3Department
of Electrical Engineering, Columbia University, USA, 4Department of Otolaryngology,
Columbia University, USA
1

S8-3

Dual-mode OCT system for vibrometry in mammalian hearing
mechanics at high frequencies
Fangyi Chen1), Cuixia Guo2), Xiaojie Yang1), Yonghong He2)

1
Department of Biomedical Engineering, Southern Univ. of Sci. & Tech., China, 2 Graduate
School at Shenzhen, Tsinghua University, China

S8-4

In-Vivo Nanomechanics in the Miniaturized Hearing Organ of an
InsectManuela Nowotny1), Jan Scherberich1), Jennifer Hummel1),
Stefan Schoneich2)

Institute of Cell Biology and Neurosciences, Goethe University, Germany, 2 Institute for
Biology, University of Leipzig, Germany

1

S8-5

Nonlinear micromechanics of the organ of Corti in the low-frequency
region of the cochlea
Tobias Reichenbach, Nikola Ciganovic
Imperial College London, UK

Symposium9 (International Scientific Program Committee Symposium)【Room I】5F, Conference Center

March 29, Fri., 10:00-12:00
S9

Metabolic syndrome and bone metabolism (TPS, Thailand)
Mahidol University, Thailand)

S9-1

Diabetic osteopathy and impaired intestinal calcium absorption indiabetes mellitus
Narattaphol Charoenphandhu1,2,3,4)Center of Calcium and Bone Research (COCAB), Faculty of Science, Mahidol University,
Thailand, 2Department of Physiology, Faculty of Science, Mahidol University, Thailand,Institute of Molecular Biosciences, Mahidol University, Thailand, 4The Academy of
Science, The Royal Society of Thailand, Thailand
1

3

S9-2

Is Metabolic Syndrome a Concern for Osteoporosis?
Siriporn C Chattipakorn1,2)

Neurophysiology Unit, Cardiac Electrophysiology Research and Training Center,
Faculty of Medicine, Chiang Mai University, Thailand, 2Department of Oral Biology and
Diagnostic Sciences, Faculty of Dentistry, Chiang Mai University, Thailand

1

S9-3

The effect of high-fat diet on maternal bone microstructure and themetabolic parameters in rats
Panan Suntornsaratoon1,2), Narattaphol Charoenphandhu1,2)

Department of Physiology, Faculty of Science, Mahidol University, Thailand, 2Center ofCalcium and Bone Research, Faculty of Science, Mahidol University, Thailand

1

S9-4

Proton-mediated regulation of physiological and pathological osteoclast functions
Miyuki Kuno

Department of Anesthesiology, Osaka City University, JapanDAY 2

Chair: Narattaphol Charoenphandhu (Center of Calcium and Bone Research (COCAB),

Symposium10
March 29, Fri., 10:00-12:00
S10【Room J】2F, Exhibition Hall

Neural circuit basis of behavioral physiology

Shi-Bing Yang (Institute of Biomedical Sciences, Academia Sinica, Taiwan)
Chair:
Co-Chair: Tsung-Han Kuo (National Tsing Hua University, Taiwan)
S10-1

Functional Dissection of the Central Glucoregulatory circuits
Shi-Bing Yang, Hsin-Ju Tsai

Institute of Biomedical Sciences, Academia Sinica, Taiwan

S10-2

Modeling of group size dependent aggressive behavior in the cricket
Hitoshi Aonuma

Research Institute for Electronic Science, Hokkaido University, Japan

S10-3

Neural basis of infant attachment and separation anxiety
Kumi O Kuroda1), Sachine Yoshida1,2)

1
Lab for Affiliative Social Behavior, RIKEN Center for Brain Science, Japan, 2Departmentof Anatomy, Faculty of Medicine, Toho University, Japan

S10-4

Set the threshold for surrender in social conflicts
Ming-Yi Chou1), Hitoshi Okamoto2)

Department of Life Science, National Taiwan University, Taiwan, 2RIKEN Center for Brain
Science, Japan

1

S10-5

Dissecting the neural circuits mediating female fertility in health anddiseaseRebecca Campbell

Centre for Neuroendocrinology, Department of Physiology, University of Otago, New
ZealandSymposium11
March 29, Fri., 10:00-12:00
S11【Room K】2F, Exhibition Hall

Advances in the mastication and swallowing physiology to prepare foran aging society

S11-1

Properties of Phox2b-expressing premotor neurons targeting jawmuscle motoneurons
Tomio Inoue

Department of Oral Physiology, Showa University School of Dentistry, Japan

S11-2

Development of masticatory performance as a novel biomarker ofgeneral health
Takahiro Ono

Graduate School of Medical and Dental Sciences, Niigata Univ., Japan

S11-3

Are respiratory-swallowing disturbances indicators of early dementia?
Mathias Dutschmann, Davor Stanic

Florey Institute of Neuroscience and Mental Health, Australia

S11-4

Coordination between swallowing and breathing: pathophysiology
and its clinical significanceYoshitaka Oku

Department of Physiology, Hyogo College of Medicine, Japan

S11-5

Non-invasive methods to evaluate the swallowing function

Makito Iizuka1), Kazuhide Tomita2), Reiko Takeshima3), Masahiko Izumizaki1)

1
Department of Physiology, Showa University School of Medicine, Japan, 2Departmentof Physical Therapy, Ibaraki Prefectural University of Health Sciences, Japan, 3Center for
Medical Sciences, Ibaraki Prefectural University of Health Sciences, Japan

DAY 2

Yoshitaka Oku (Hyogo College of Medicine, Japan)
Chair:
Co-Chair: Makito Iizuka (Showa University School of Medicine, Japan)

Symposium12
March 29, Fri., 10:00-12:00
S12【Room L】3F, Exhibition Hall

New insights into baroreflex function for cerebral and cardiovascularregulation: Implications for human health and disease

Shigehiko Ogoh (Toyo University, Japan)
Chair:
Co-Chair: Paul J Fadel (University of Texas at Arlington, USA)
S12-1

The effect of baroreflex function on cerebral blood flow regulation
during exercise
Shigehiko Ogoh

Department of Biomedical Engineering, Toyo University, Japan

S12-2

Arterial and cardiopulmonary baroreflex control of sympathetic nerve
activity during exercise
Paul J Fadel

Department of Kinesiology, University of Texas at Arlington, USA

S12-3

Sex Differences in Baroreflex Function
Qi Fu1,2)

1Internal Medicine, University of Texas Southwestern Medical Center, USA, 2Institute for
Exercise and Environmental Medicine at Texas Health Presbyterian Hospital, USA

S12-4

Exercise pressor reflex and arterial baroreflex function in cardiovascular disease
Scott Alan Smith

School of Health Professions, Department of Health Care Sciences, University of Texas
Southwestern Medical Center, USA

S12-5

Modulation of cardiac baroreflex by central command in daily life
Kanji Matsukawa, Kei Ishii, Ryota Asahara

Department of Integrative Physiology, Hiroshima University, JapanSymposium13
March 29, Fri., 10:00-12:00
S13【Room M】3F, Exhibition Hall

The role of the sympathetic nerves in health and disease

S13-1

Longterm effects of renal denervation in an ovine model ofhypertensive chronic kidney disease
Kate M Denton, Reetu R Singh

Department of Physiology, Monash University, Australia

S13-2

Sympathetic regulation in anaphylactic shock or feeding suppression
Mamoru Tanida

Department of Physiology II, Kanazawa Medical University, Japan

S13-3

The importance of sympathetic nervous system influences in thecoronary vasculature
James T. Pearson1,2), Daryl O. Schwenke3), Hirotsugu Tsuchimochi1),
Takashi Sonobe1), Vijayakumar Sukumaran1), Mikiyasu Shirai4)

Department of Cardiac Physiology, National Cerebral & Cardiovascular Center, Japan,
Department of Physiology, Monash University, Australia, 3Department of Physiology,
University of Otago, New Zealand, 4Department of Advanced Medical Research for
Pulmonary Hypertension, National Cerebral & Cardiovascular Center, Japan

1
2

S13-4

Altered differential control of cardiac and renal sympathetic nerve
activity in hypertension
Rohit Ramchandra1), Darvina Mahesh1), Jaap Joles2), Tycho Tromp1,2)

1
Department of Physiology, The University of Auckland, New Zealand, 2University
Medical Centre, Utrecht University, The Netherlands

S13-5

Cortical and subcortical structures involved in the generation ofmuscle sympathetic nerve activity
Vaughan G Macefield1,2,3), Luke A Henderson4)

Human Autonomic Neurophysiology Lab, Baker Heart and Diabetes Institute, Australia,
School of Medicine, Western Sydney University, Australia, 3Neuroscience Research
Australia, Australia, 4Discipline of Anatomy & Histology, Sydney Medical School,
University of Sydney, Australia
1
2

DAY 2

Chair: Rohit Ramchandra (The University of Auckland, New Zealand)Symposium14 (Local Organizing Committee Symposium)
March 29, Fri., 15:10-17:10
S14【Room A】1F, Conference Center

Advances in understanding cerebellar LTD and motor learning:
Masao Ito Symposium

Chairs: Yasuo Kawaguchi (National Institute for Physiological Sciences, Japan)

Masanobu Kano (Graduate School of Medicine, The University of Tokyo, Japan)
Kazuo Kitamura (University of Yamanashi, Japan)

S14-1

Discovery and investigation of cerebellar long-term depression at
Masao Ito’s lab
Masanobu Kano1,2)

Department of Neurophysiology, Graduate School of Medicine, The University ofTokyo, Japan, 2International Research Center for Neurointelligence (WPI-IRCN), The
University of Tokyo Institutes for Advanced Study (UTIAS), The University of Tokyo,
Japan
1

S14-2

Temporal aspects of cerebellar long-term synaptic depression
Keiko Tanaka-Yamamoto, Taegon Kim, Yukio Yamamoto

Center for Functional Connectomics (CFC), Korea Institute of Science and Technology(KIST), Korea

S14-3

LTD and the search for the cerebellar memory trace
Christian Hansel

Department of Neurobiology, University of Chicago, USA

S14-4

New optogenetical tool clarified that the cerebellar LTD was essential
for motor learning
Shinji Matsuda

Department of Engineering Science, The University of Electro-Communications, Japan

S14-5

Specialization of the rules for cerebellar LTD at different parallel fiberPurkinje cell synapses
Jennifer L RaymondDepartment of Neurobiology, Stanford University School of Medicine, USASymposium15 (Local Organizing Committee Symposium)
March 29, Fri., 15:10-17:10
S15【Room B】3F, Conference Center

Thermal biology: A new world of life science(whole day symposium) part II‘Thermal Biology’ of Mext, Japan)

Chairs: Makoto Tominaga (National Institute for Physiological Sciences, Japan)

Kazuhiro Nakamura (Nagoya University Graduate School of Medicine, Japan)

S15-1

Effects of temperature on seasonal adaptation: Towards theunderstanding of human seasonality
Takashi Yoshimura1,2,3)

Institute of Transformative Bio-Molecules (WPI-ITbM), Nagoya University, Japan,
Graduate School of Bioagricultural Sciences, Nagoya University, Japan, 3Division of
Seasonal Biology, National Institute for Basic Biology, Japan
1
2

S15-2

Mechanisms of psychological impacts on thermoregulation andmetabolism
Kazuhiro Nakamura

Department of Integrative Physiology, Nagoya University Graduate School of Medicine,
Japan

S15-3

TRP ion channels - internal/deep-brain temperature sensors andguardians of homeostasis?
Jan Erik Siemens1), Gretel B. Kamm1), Juan C. Boffi2), Hong Wang1,4),
Thomas Kuner2), Kun Song1,3)

1
Department of Pharmacology, Heidelberg University, Germany, 2Department of
Functional Neuroanatomy, Heidelberg University, Germany, 3Max Delbruck Center for
Molecular Medicine (MDC), Germany , 4The Brain Cognition & Brain Disease Institute,
University Town of Shenzhen, China

DAY 2(Co-organized By Grant-In-Aid For Scientific Research on Innovative Areas

Symposium16 (International Scientific Program Committee Symposium)
March 29, Fri., 15:10-17:10
S16【Room C】3F, Conference Center

Gastrointestinal Control of Energy Metabolism (CAPS, China)

Chairs: Weizhen Zhang (Peking University Health Science Center, China)

Jinxia Zhu (Capital Medical University, China)

S16-1

Gastric mTORC1 as a fuel sensing mechanism and its role in lipid
homeostasis
Weizhen Zhang

Department of Physiology and Pathophysiology, Peking University Health Science
Center, China

S16-2

Gut-derived Dopamine and Its Regulation on Intestinal Barrier
Function
Jinxia Zhu, Xiaoyan Feng, Chenzhe Liu, Xiaoli Zhang

Department of Physiology and Pathophysiology, Capital Medical University, China

S16-3

Hormonal and neuronal regulatory mechanisms of gastrointestinal
motility in the Suncus murinus
Ichiro Sakata, Takafumi Sakai

Graduate school of Science and Engineering, Saitama University, Japan

S16-4

The X/A-like cell as a regulator of food intake
Andreas Stengel1,2)

Psychosomatic Medicine, University Tuebingen, Germany, 2Psychosomatic Medicine,
Charité University, Germany

1

S16-5

Regulation of GLP1 secretion and mitochondrial function by Berberine
in colon enterocytes
Jianping Ye

Central Lab, Shanghai Jiaotong University Affiliated 6th People's Hospital East, China

Symposium17 (Local Organizing Committee Symposium )March 29, Fri., 15:10-17:10
S17【Room D】4F, Conference Center

Teaching physiology; International perspectives(whole day symposium) part II

S17-1

Integration of social practice and medical knowledge in an outcomebased curriculum at NCKU Medical School
Mei-Ling Tsai

Department of Physiology, National Cheng Kung University, Taiwan

S17-2

PHY-STORY : Students Discovering and Telling their Stories ofPhysiology
Cheng Hwee Ming

Department Physiology, Faculty of Medicine, University Malaya, Malaysia

S17-3

How to make students alert during lectures
Mangala Gunatilake

Dept. of Physiology, Faculty of Medicine, University of Colombo, Sri Lanka

S17-4

Teaching Physiology - Students’ Voice
Noriyuki Koibuchi

Gunma University Graduate School of Medicine, JapanDAY 2

Chair: Noriyuki Koibuchi (Gunma University Graduate School of Medicine, Japan)

Symposium18
March 29, Fri., 15:10-17:10
S18【Room E】4F, Conference Center

Dynamics of membrane trafficking and intracellular signaling

Yoh Takuwa (Kanazawa University, Japan)
Chair:
Co-Chair: Yusuke Ohba (Hokkaido University, Japan)
S18-1

Optogenetic control of diverse molecular and cellular processes in
the mouse brain.
Won Do Heo1,2)

1Department of Biological Sciences, KAIST, Korea, 2Center for Cognition and Sociality,
IBS, Korea

S18-2

Imaging secretory cells and molecular configurations of exocytic
proteins
Noriko Takahashi1), Hiroyasu Hatakeyama1), Tomomi Oshima1),
Yuichi Morimoto2), Haruo Kasai2)

1
Department of Physiology, Kitasato University School of Medicine, Japan, 2Structural
Physiology, Graduate School of Medicine, The University of Tokyo, Japan

S18-3

Fluorescence Imaging of membrane dynamics and intracellularsignaling
Yusuke Ohba

Department of Cell Physiology, Faculty of Medicine, Hokkaido University, Japan

S18-4

Essential role of class II PI3K in endocytosis and endosomal signaling
Kazuaki Yoshioka1), Khin Thuzar Aung1), Md Azadul Kabir Sarker1),
Sho Aki1), Kuntal Biswas1), Noriko Takuwa1,2), Yoh Takuwa1)

1
Department of Physiology, Kanazawa University, Japan, 2Department of Health
Science, Ishikawa Prefectural Nursing University, Japan

S18-5

Morphological changes of plasma membrane and protein assembly
during clathrin-mediated endocytosis
Shige H. Yoshimura1), Aiko Yoshida1,2), Yoshitsuna Itagaki1), Yuki Suzuki3)

1
Graduate School of Biostudies, Kyoto University, Japan, 2Graduate School of Medicine,
Hokkaido University, Japan, 3Frontier Research Institute for Interdisciplinary Sciences,
Tohoku University, JapanSymposium19 (International Scientific Program Committee Symposium)
March 29, Fri., 15:10-17:10
S19【Room F】5F, Conference Center

Mitochondrial Physiology and Pathophysiology (KPS, Korea)

Jin Han (Inje University, Korea)

S19-1

Mitochondrial quality control and its metabolic regulation by reactive
persulfide species
Motohiro Nishida1,2)

Division of Cradiocirculatory Signaling, National Institute for Physiological Sciences,
National Institutes of Natural Sciences, 2Department of Translational Pharmaceutical
Sciences, Graduate School of Pharmaceutical Sciences, Kyushu University
1

S19-2

Regulation of systemic energy metabolism in altered mitochondrial
proteostasis
Minho Shong

Department of Internal Medicine, Chungnam National University, Korea

S19-3

Roles of mitochondrial dynamics in cellular function, development,
and differentiation
Naotada Ishihara1,2), Takaya Ishihara1,2), Emi Ogasawara1,2), Tadato Ban2)

1
Graduate School of Science, Osaka University, Japan, 2Institute of Life Science, Kurume
University, Japan

S19-4

Mitochondrial oxidative stress associated with calcium and phosphate
Kyu-Sang Park1,2)
1
2

Department of Physiology, Wonju College of Medicine, Yonsei University, Korea,
Mitohormesis Research Center, Wonju College of Medicine, Yonsei University, Korea

DAY 2

Chairs: Kyu-Sang Park (Wonju College of Medicine, Yonsei University, Korea)

Symposium20
March 29, Fri., 15:10-17:10
S20【Room G】5F, Conference Center

Adaptation mechanisms to external or internal environmental changesof respiratory system

Hiroshi Onimaru (Showa University School of Medicine, Japan)
Chair:
Co-Chair: Keiko Ikeda (International University of Health and Welfare, Japan)
S20-1

Vaginal delivery is a strong adaptation signal to start spontaneous
breathing
Keiko Ikeda1,2), Hiroshi Onimaru3), Kiyoshi Kawakami2)

Department of Physiology, International University of Health and Welfare, Japan,
Division of Biology, Center for Molecular Medicine, Jichi Medical University, Japan,
3
Department of Physiology, Showa University School of Medicine, Japan
1
2

S20-2

Pontine modulation of medullary respiratory circuit activity
Rishi R Dhingra, Mathias Dutschmann

Division of Systems Neurophysiology, The Florey Institute of Neuroscience & Mental
Health, Australia

S20-3

Hypoxic responses of the respiratory system

Yasumasa Okada1), Itaru Yazawa2), Kotaro Takeda3), Shuntaro Okazaki4),
Makoto Uchiyama5), Yuki Kurita5), Isato Fukushi1), Shigefumi Yokota6),
Yasuo Mori5), Hiroshi Onimaru7)

1
Clin. Res. Ctr., Murayama Med. Ctr., Japan, 2Global Res. Ctr. for Innovative Life Sci., Hoshi
Univ. Sch. of Pharm. & Pharmaceut. Sc, Japan, 3Sch. of Hlth. Sci., Fujita Hlth. Univ., Japan,
4
Waseda Univ., Japan, 5Dept. of Synthetic Chem. and Biol. Chem., Grad. Sch. ofEngineering, Kyoto Univ., Japan, 6Dept. of Anat. and Neurosci., Shimane Univ., Japan,
7
Showa Univ. Sch. of Med., Japan

S20-4

How hypoxia blunts respiratory arousal from sleep
Peter George Burke

Neuroscience Research Australia, Australia

S20-5

Impact of cervical spinal cord injury on respiratory motor control
Kun-Ze Lee

Department of Biological Sciences, National Sun Yat-sen University, Taiwan

Symposium21
March 29, Fri., 15:10-17:10
S21【Room H】5F, Conference Center

New Paradigm in Physiology and Pathophysiology of Coagulationfibrinolysis System

S21-1

Overview of the cross-talk between the coagulation-fibrinolysis
System and cellular functions
Tetsumei Urano, Yuko Suzuki

Department of Medical Physiology, Hamamatsu University School of Medicine, Japan

S21-2

Cell surface-modified fibrinolysis; contribution of vascular endothelial
cells and platelets
Yuko Suzuki, Hideto Sano, Naoki Honkura, Tetsumei Urano

Department of Medical Physiology, Hamamatsu University School of Medicine, Japan

S21-3

Novel role of coagulation factor XI as a regulator of vascular smoothmuscle function
Katsuya Hirano, Wenhua Liu

Department of Cardiovascular Physiology, Faculty of Medicine, Kagawa University,
Japan

S21-4

Endosomal Platforms for Protease Signaling
Nigel W. Bunnet

Columbia University

S21-5

Fibrinolysis and immunity: a new paradigm
Robert Lindsay Medcalf

Australian Centre for Blood Diseases, Monash University, Australia

DAY 2

Katsuya Hirano (Kagawa University, Japan)
Chair:
Co-Chair: Tetsumei Urano (Hamamatsu University School of Medicine, Japan)

Symposium22
March 29, Fri., 15:10-17:10
S22【Room I】5F, Conference Center

Proton signalings and proton-related functions

Yoshifumi Okochi (Graduate School of Medicine, Osaka University, Japan)
Chair:
Co-Chair: Ye Yu (China Pharmaceutical University, China)
S22-1

Hv1/VSOP voltage-gated proton channel inhibits migration in
response to fMLF in neutrophils
Yoshifumi Okochi, Yasushi Okamura

Integrative Physiology, Graduate School of Medicine, Osaka University, Japan

S22-2

Controlling the innate immune signaling by the proton-coupled
peptide transporters
Toshihiko Kobayashi, Noriko Toyama-Sorimachi

Department of Molecular Immunology and Inflammation, Research Institute, National
Center for Global Health and Medicine, Japan

S22-3

Otopetrins constitute a new family of proton-selective ion channels
Emily Liman

Section of Neurobiology, University of Southern California, USA

S22-4

Proton imaging in the brain using CCD-type ion image sensor
Hiroshi Horiuchi1,2,4), Junko Ishida1,4), Masakazu Agetsuma1,2,4),Kazuaki Sawada3,4), Junichi Nabekura1,2,4)

Division for Homeostatic Development, National Institute for Physiological Sciences,
Japan, 2Department of Physiological Sciences, The Graduate School for Advanced
Study, Hayama, Japan, 3Department of Electronic and Information Engineering,
Toyohashi University of Technology, Japan, 4Core Research for Evolutional Science andTechnology, Japan Science and Technology Agency, Japan
1

S22-5

A nonproton ligand sensor in the acid-sensing ion channel
Ye Yu

China Pharmaceutical University, China

Symposium23
March 29, Fri., 15:10-17:10
S23【Room J】2F, Exhibition Hall

Glia and Neurological Diseases: from Physiological to Pathological
Roles of Astrocytes and Microglia

S23-1

Physiological function of microglia and their effect on neuronal circuits
Hiroaki Wake

Division of System Neuroscience, Kobe University Graduate School of Medicine, Japan

S23-2

The roles of astrocytes and microglia in glutamate release after brain
injuryWen-Biao Gan, Sally Levinson, Joseph Cichon, Mirko Santello
Skirball Institute, New York University School of Medicine, USA

S23-3

Bidirectional regulation of synapse remodeling by reactive astrocytes
Schuichi Koizumi

Department of Neuropharmacology, Interdisciplinary Graduate School of Medicine,
University of Yamanashi, Japan

S23-4

The role of cortical astrocytes in establishing peripheral neuropathic
pain
Sun Kwang Kim

Department of Physiology, College of Korean Medicine, Kyung Hee University, Korea

DAY 2

Sun Kwang Kim (College of Korean Medicine, Kyung Hee University, Korea)
Chair:
Co-Chair: Hiroaki Wake (Kobe University Graduate School of Medicine, Japan)

Symposium24
March 29, Fri., 15:10-17:10
S24【Room K】2F, Exhibition Hall

Complexity and Diversity of Motility Regulation in Smooth Muscle

Shinsuke Nakayama (Nagoya University, Japan)
Chair:
Co-Chair: Masaru Watanabe (Tokyo Metropolitan University, Japan)
S24-1

Morphological Study of Motility Regulation Mechanisms in Gastrointestinal Tract
Hiromi Tamada1,2)

Graduate School of Medicine, Nagoya University, Japan, 2Japan Society for the
Promotion of Science, Japan

1

S24-2

Differnece of pacamaking activity of interstitial cells of Cajal between
small and large intestine
Jae Yeoul Jun

Department of Physiology, University of Chosun, Korea

S24-3

Characteristic motility regulation of smooth muscle in lower urinary
tract
Shunichi Kajioka1), Tomoko Maki2), Maya Hayashi2), Nouval Shahab1),
Shinsuke Nakayama3), Toshiyuki Sasaguri1)

1
Department of Clinical Pharmacology, Kyushu University, Japan, 2Department ofUrology, Kyushu University, Japan, 3Department of Cell Physiology, Nagoya University,
Japan

S24-4

Regulation of thick and thin filaments organization during smoothmuscle contraction
Masaru Watanabe1), Naoya Nakahara2), Yukisato Ishida1,3)

Laboratory of Physiology, Graduate School of Human Health Sciences, Tokyo
Metropolitan University, Japan, 2The Jikei University, Japan, 3Bunkyo Gakuin University,
Japan

1

Symposium25
March 29, Fri., 15:10-17:10
S25【Room L】3F, Exhibition Hall

Calcium signaling in heart disease

S25-1

Alterations of shear-Ca2+ signaling in atrial myocytes under chronicpressure and volume overload
Sun-Hee Woo, Min-Jeong Son, Qui A Le, Joon-Chul Kim
College of Pharmacy, Chungnam National University, Korea

S25-2

Mechanisms for sex differences in drug-induced arrhythmia
Junko Kurokawa

School of Pharmaceutical Sciences, University of Shizuoka, Japan

S25-3

Sarcoplasmic reticulum calcium leak promotes atrial fibrillation
Wenjun Xie, Ying Qi, Jingjing Li, Wenjin He

School of Life Science and Technology, Xi'an Jiaotong University, China

S25-4

Mechanism and therapeutic strategies for arrhythmogenic diseases
caused by RyR2 mutations
Nagomi Kurebayashi

Department of Pharmacology, Faculty of Medicine, Juntendo University, Japan

S25-5

Conjunct JPH2-CAV3 Transcription Enhanced Ca Signaling Efficiency in Hibernating Ground Squirrels
Shi-Qiang Wang, Lei Yang, Rong-Chang Li, Bin Xiang, Yi-Chen Li,
Li-Peng Wang, Xiao-Ting Wang
College of LIfe Sciences, Peking University, China

DAY 2

Shi-Qiang Wang (Peking University, China)
Chair:
Co-Chair: Sun-Hee Woo (Chungnam National University, Korea)

Symposium26
March 29, Fri., 18:30-20:00
S26【Room A】1F, Conference Center

Synaptic remodeling and beyond in health and disease

Ryuta Koyama (The University of Tokyo, Japan)
Chair:
Co-Chair: Naofumi Uesaka (The University of Tokyo, Japan)
S26-1

Neuronal activity-dependent synaptic pruning by microglia
Ryuta Koyama

Graduate School of Pharmaceutical Science, The University of Tokyo, Japan

S26-2

Interleukin-1s-mediated effects of inflammation on visual circuit development in the zebrafish
Edward S Ruthazer, Cynthia M Solek, Nasr AI Farooqi, Niklas S Brake
Montreal Neurological Institute, McGill University, Canada

S26-3

Photooxygenation reduces the Aβ level in the brains of Alzheimer
disease model mice
Yukiko Hori1, Shuta Ozawa1, Youhei Sohma2, Motomu Kanai2,
Taisuke Tomita1

Laboratory of Neuropathology and Neuroscience, Graduate School of Pharmaceutical
Sciences, The University of Tokyo, Japan, 2Laboratory of Synthetic Organic Chemistry,
Graduate School of Pharmaceutical Sciences, The University of Tokyo, Japan

1

S26-4

Regulation of aberrant synaptic remodeling in the thalamus triggeredby peripheral nerve injury
Yoshifumi Ueta, Mariko Miyata

Dept Physiol, Div Neurophysiol, Grad Sch Med, Tokyo Women's Med Univ, Japan

S26-5

Activity-dependent synapse elimination in the developing cerebellum
Naofumi Uesaka, Tzu-Huei Kao, Masanobu Kano

Graduate School Medicine, The University of Tokyo, JapanSymposium27
March 29, Fri., 18:30-20:00
S27【Room B】3F, Conference Center

Regulation of cell functions by phosphoinositides

S27-1

A new mechanism of Ca2+-independent voltage-dependent secretionin dorsal root ganglion neurons
Zhuan Zhou1), Yuan Wang1), Hiroki Arima2), Rong Huang1), Yuqi Hang1,
Xingyu Du1), Feipeng Zhu1), Zuying Chai1), Changhe Wang1),
Yasushi Okamura2)
1

S27-2

Peking University, China, 2Osaka University, Japan

Functional analysis of voltage-sensing phosphatase in mouse sperm
Takafumi Kawai1), Haruhiko Miyata2), Hiroki Nakanishi3), Souhei Sakata1,4,
Yoshifumi Okochi1), Masahiko Watanabe5), Kenji Sakimura6),
Takehiko Sasaki7,8), Masahito Ikawa2), Yasushi Okamura1)

Graduate School of Medicine, Osaka University, Japan, 2RIMD, Osaka University, Japan,
Research Center for Biosignal, Akita University, Japan, 4Dept. of Physiolgy, Osaka
Medical College, Japan, 5Graduate School of Medicine, Hokkaido University, Japan,
6
Brain Research Institute, Niigata University, Japan, 7Graduate School of Medicine, Akita
University, Japan, 8Medical research institute, Tokyo Medical and Dental University,
Japan
1
3

S27-3

Regulation of ion channel functions by phosphoinositides
Byung C. Suh

Department of Brain and Cognitive Sciences, DGIST, Korea

S27-4

Molecular mechanisms of phosphoinositide signaling

Junko Sasaki1), Satoshi Eguchi2), Hiroki Nakanishi3), Takehiko Sasaki1)

1
Medical Research Institute, Tokyo Medical and Dental University, Japan, 2Departmentof Medical Biology, Graduate School of Medicine, Akita University, Japan, 3ResearchCenter for Biosignal, Akita University, Japan

DAY 2

Zhuan Zhou (Peking University, China)
Chair:
Co-Chair: Yasushi Okamura (Osaka University, Japan)

Symposium28
March 29, Fri., 18:30-20:00
S28【Room C】3F, Conference Center

Molecular evidences Link Physical Exercise to Cardiovascular Improvement

Chair:
Junjie Xiao (Shanghai University, China)
Co-Chair: Julie McMullen (Baker Heart and Diabetes Institute, Australia)
S28-1

Non-coding RNA basis of exercise induced physiological hypertrophy
Junjie Xiao

Institute of Cardiovascular Sciences, School of Life Science, Shanghai University, China

S28-2

Exercise Training Prevents Cardiac Injury Induced by Sympathetic
StressHan Xiao, Youyi Zhang

Institute of vascular medicine, Peking University Third Hospital, China

S28-3

Targeting a critical regulator of exercise-induced cardiac hypertrophy,
PI3K, in the failing heart
Julie Rae Mcmullen

Baker Heart and Diabetes Institute, Australia

Symposium29
March 29, Fri., 18:30-20:00
S29【Room D】4F, Conference Center

New insights into central mechanisms underlying hypertension

S29-1

Central mechanisms of hypertension: brain-heart-kidney connection
Yoshitaka Hirooka

Department of Medical Technology and Sciences, International University of Healthand Welfare, Japan

S29-2

Visceral afferent modulation for regulating sympathetic activity incardiorespiratory disease
Julian FR Paton

Department of Physiology, University of Auckland, New Zealand

S29-3

Role of hypothalamus on the cardiovascular regulation during
repeated acute psychological stressJouji Horiuchi, Ena Yamamoto, Takatoshi Horiuchi, Misaki Ichikawa
Department of Biomedical Engineering, Toyo University, Japan

S29-4

NTS gene expression profiles underlying basal blood pressure levels:
Focus on disease and gender
Sabine S. S. Gouraud1,2), Makiko Onishi3), Linh Thuy Pham2,3),
Ko Yamanaka4), Hidefumi Waki4)

Dept. Biology, Ochanomizu University, Japan, 2Grad Sch General Educational Research,
Ochanomizu University, Japan, 3Grad Sch Humanities and Sciences, Ochanomizu
University, Japan, 4Dept. Physiology, Grad Sch Health and Sports Science, Juntendo
University, Japan
1

S29-5

Brain molecular mechanisms underlying anti-hypertensive effect ofdaily exercise
Hidefumi Waki1), Ko Yamanaka1), Kei Tsukioka1), Keisuke Tomita1),
Miwa Takagishi2), Sabine S. S. Gouraud3)

Department of Physiology, Graduate School of Health and Sports Science, Juntendo
University, Japan, 2Department of Therapeutic Health Promotion, Kansai University of
Health Sciences, Japan, 3Department of Biology, Faculty of Science, Ochanomizu
University, Japan
1

DAY 2

Julian FR Paton (Department of Physiology, University of Auckland, New Zealand)
Chair:
Co-Chair: Sabine S. S. Gouraud (Ochanomizu University, Japan)

Symposium30
March 29, Fri., 18:30-20:00
S30【Room E】4F, Conference Center

Substance abuse and addiction ~ From basic science to regulatory
scienceTomoaki Shirao (Gunma University Graduate School of Medicine, Japan)
Chair:
Co-Chair: Bart A Ellenbroek (Victoria University of Wellington, New Zealand)
S30-1

An overview of recent emergence of new psychoactive substances(NPS)
Ruri Kikura-Hanajiri

Division of Pharmacognosy, Phytochemistry and Narcotics, National Institute of Health
Sciences, Japan

S30-2

High-throughput imaging analysis using cultured neurons for
detecting phencyclidine-like substances
Kenji Hanamura1), Toshinari Mitsuoka1), Ruri Kikura-Hanajiri2),
Yuko Sekino3), Tomoaki Shirao1)

Department of Neurobiology and Behavior, Gunma University Graduate School of
Medicine, Japan, 2Division of Pharmacognosy, Phytochemistry and Narcotics, National
Institute of Health Sciences, Japan, 3Endowed Laboratory of Human Cell-Based Drug
Discovery, Graduate School of Pharmaceutical Sciences, The University of Tokyo, Japan

1

S30-3

GIRK channels and NMDA receptor GluN2D subunit in signal
pathways from addictive substances
Kazutaka Ikeda

Department of Psychiatry and Behavioral Sciences, Tokyo Metropolitan Institute ofMedical Science, Japan

S30-4

The serotonin transporter (SERT) as a genetic risk factor for drug
addiction
Bart A Ellenbroek

School of Psychology, Victoria University of Wellington, New ZealandSymposium31
March 29, Fri., 18:30-20:00
S31【Room F】5F, Conference Center

Genomics of Sports and Exercise

S31-1

Implication of genetic polymorphisms on sports performance
Eri Miyamoto-Mikami

Graduate School of Health and Sports Science, Juntendo University, Japan

S31-2

Genomic investigations of skeletal muscle function
Ola Hansson1,2)

Department of Clinical Sciences, Lund University, Sweden, 2Institute for Molecular
Medicine Finland (FIMM), Helsinki University, Finland

1

S31-3

A Kinesio-Genomic Effect of mtDNA Polymorphism in the MOTS-c on
Diabetes
Hirofumi Zempo1,2)

Department of Administrative Nutrition, Faculty of Health and Nutrition, Tokyo Seiei
College, Japan, 2Graduate School of Health and Sports Science, Juntendo University,
Japan

1

DAY 2

Noriyuki Fuku (Juntendo University, Japan)
Chair:
Co-Chair: Ola Hanson (Lund University, Sweden)

Symposium32 (Local Organizing Committee Symposium)
March 29, Fri., 18:30-20:00
S32【Room G】5F, Conference Center

Membrane transporters related to diseases and drug development

Naohiko Anzai (Chiba University School of Medicine, Japan)
Chair:
Co-Chair: Stefan Broer (The Australian National University, Australia)
S32-1

The amino acid transporter SLC6A19 as a target to improve metabolic
diseases
Stefan Broer

Research School of Biology, Australian National University, Australia

S32-2

L-type Amino Acid Transporters and Cancer
Arthit Chairoungdua1,2)

1
Department of Physiology, Faculty of Science, Mahidol University, Thailand, 2Excellent
Center for Drug Discovery (ECDD), Mahidol University, Thailand

S32-3

Phosphate balance in the body and epithelial phosphate transporters
Hiroko Segawa, Yuji Shiozaki, Ichiro Kaneko, Ken-Ichi Minamoto

Department of Molecular Nutrition Institute of Biomedical Sciences, Tokushima
University Graduate School, Japan

S32-4

Genomic analysis of Japanese Cystinuria patients through a nextgeneration sequence
Shinichi Sakamoto1), Yukio Naya2), Yasuhiro Shigeta3), Masaaki Fujimura4),
Chiaki Inada1,8), Yuzuru Ikehara6), Yoshikatsu Kanai7), Naohiko Anzai5),
Tomohiko Ichikawa1,8)

Department of Urology, Chiba University Graduate School of Medicine, Japan,
Department of Urology, Teikyo University Chiba Medical Center, Japan, 3Nishifunabashi
Urology Clinic, Japan, 4Department of Urology, Saiseikai Narashino Hospital, Japan,
5
Department of Pharmacology, Chiba University Graduate School of Medicine, Japan,
6
Department of Tumor Pathology, Chiba University Graduate School of Medicine,Japan, 7Department of Bio-system Pharmacology, Osaka University Graduate School of
Medicine, Japan, 8Division of Clinical Genetics, Chiba University Graduate School of
Medicine, Japan
1
2

Symposium33
March 29, Fri., 18:30-20:00
S33【Room H】5F, Conference Center

New insights into Endocrinology and Metabolism

S33-1

Effects of perinatal hypothyroidism on brain development

Izuki Amano, Yusuke Takatsuru, Ayane Kate Ninomiya, Hiroyuki Yajima,
Miski Aghnia Khairinisa, Michifumi Kokubo, Machiko Suda, Asahi Haijima,
Noriyuki Koibuchi
Department of Integrative Physiology, Gunma University Graduate School of Medicine,
Japan

S33-2

Revealing role of thyroid hormone on autophagy regulation in skeletal
muscleRonny Lesmana1,2)

Departement of basic science, Physiology Division, Faculty of Medicine, Universitas
Padjadjaran, Indonesia, 2Central Laboratory, Universitas Padjadjaran, Indonesia

1

S33-3

The role of nuclear receptor corepressors NCoR1 and SMRT on
physiologic function in the mouse
Megan Jean Ritter, Izuki Amano, Kristen Vella, Anthony N Hollenberg

Weill Cornell Medicine, Department of Medicine, Division of Endocrinology, Diabetes
and Metabolism, USA

S33-4

The Protective Roles of Cardiac Macrophages in Heart Failure
Munehiko Shibata

Division of Endocrinology, Diabetes and Metabolism, Beth Israel Deaconess Medical
Center, USA

DAY 2

Izuki Amano (Gunma University Graduate School of Medicine, Japan)
Chair:
Co-Chair: Ronny Lesmana (Universitas Padjadjaran, Indonesia)

Symposium34
March 29, Fri., 18:30-20:00
S34【Room I】5F, Conference Center

Life Style Related Diseases in Asia: Underlying Mechanisms, Functions
and Behavioural Transitions

Kanwal Preet Kochhar (All India Institute of Medical Sciences, India)
Chair:
Co-Chair: Kishore Kumar Deepak (All India Institute of Medical Sciences, India)
S34-1

Obesity : a matter of fat taste
Naim A Khan

Universite de Bourgogne, France

S34-2

The autonomic modulation for alleviating life style diseases
Kishore Kumar Deepak

Department of Physiology, All India Institute of Medical Sciences, India

S34-3

Cognitive Neurophysiological Imaging and Neuromodulation in Obesity
Kanwal Preet Kochhar

Department of physiology, All India Institute of Medical Sciences, India

S34-4

Role of Yoga-based intervention in managing obesity and inflammation
Raj Kumar Yadav

Department of Physiology, All India Institute of Medical Sciences, India

S34-5

Food addiction and its link to obesity
Siddharth Sarkar

Department of Psychiatry and NDDTC, AIIMS, India

Symposium35
March 29, Fri., 18:30-20:00
S35【Room J】2F, Exhibition Hall

Frontiers in Ca2+ release research in skeletal muscle: 50th anniversary
from discovery of Ca2+-induced Ca2+ release

S35-1

Identification of novel inhibitors of Ca2+-induced Ca2+ release for
RyR1-related muscle diseases
Takashi Murayama

Department of Pharmacology, Juntendo University School of Medicine, Japan

S35-2

Interaction of junctophilins and the CaV1.1 is essential for the skeletal
muscle contraction
Tsutomu Nakada, Toshihide Kashihara, Masatoshi Komatsu,
Mitsuhiko Yamada

Department of Molecular pharmacology, Shinshu University School of Medicine, Japan

S35-3

Analysis of disease mutants of type 1 ryanodine receptor using
molecular dynamics and Ca2+ imaging
Toshiko Yamazawa

Department of Molecular Physiology, The Jikei University School of Medicine, Japan

S35-4

Structural basis for the gating, insecticide binding and resistance ofinsect ryanodine receptor
Zhiguang Yuchi, Lianyun Lin, Zhiyuan Hao

School of Pharmaceutical Science and Technology, Tianjin University, China

DAY 2

Takashi Murayama (Juntendo University School of Medicine, Japan)
Chair:
Co-Chair: Zhiguang Yuchi (Tianjin University, China)

Symposium by the PSJ Committee on the Promotion of Gender Equality【Room M】3F, Exhibition Hall

March 29, Fri., 12:20-13:20

Seeking Gender Equality in Science. A comparison of issues andinitiatives in Japan and New Zealand

MLS

Chairs: Yasuhiko Saito (Nara Medical University, Japan)

Tomoe Nakamura-Nishitani (National Cerebral and Cardiovascular Center Institute,Japan)MLS-1

Making room at the table: Gender equality initiatives at the Okinawa
Institute of Science and Technology (OIST) Graduate University
Gail Tripp

Okinawa Institute of Science and Technology Graduate University, Japan

MLS-2

Summary of the 4th Large-Scale Survey of Gender-Equality status inscientific professions
Tomoe Nakamura-Nishitani

National Cerebral and Cardiovascular Center Institute, Japan

Luncheon Seminar1【Room B】3F, Conference Center

March 29, Fri., 12:20-13:20
LS1

Structural Analysis of membrane proteins by Cryo-EM(Co-sponsored by Thermo Fisher Scientific)

LS1-1

Single particle cryo-EM of membrane proteins
Yifan Cheng1,2)

1
Howard Hughes Medical Institute, USA, 2Department of Biochemistry and Biophysics,
The University of California, USA

Luncheon Seminar2【Room C】3F, Conference Center

March 29, Fri., 12:20-13:20
LS2- Visualize Cellular Function - Application of DOJINDO Reagents(Co-sponsored by DOJINDO LABORATORIES)

Chair: Kazuhito Tomizawa (Kumamoto University, Japan)
Fan-Yan Wei
Department of Molecular Physiology, Faculty of Life Sciences, Kumamoto University,
Japan

DAY 2

Chair: Makoto Tominaga (National Institute for Physiological Sciences, Japan)

Luncheon Seminar3

Talk in Japanese【Room D】4F, Conference Center

March 29, Fri., 12:20-13:20
LS3

Physiological role of brain glycogen in rats with prolonged exerciseinduced central fatigue: Usefulness of metabolomics study(Co-sponsored by Human Metabolome Technologies, Inc.)

Chair: Kentaro Kawanaka (University of Fukuoka, Japan)
Hideaki Soya1,2,3)
1
Laboratory of Exercise Biochemistry and Sport Neuroscience, Japan, 2Advanced
Research Initiative for Human High Performance (ARIHHP), 3Faculty of Health and Sport
Sciences, University of Tsukuba, Japan

Luncheon Seminar4【Room G】5F, Conference Center

March 29, Fri., 12:20-13:20
LS4

Absorption of Rare Sugars in the Small Intestine(Co-sponsored by Matsutani Chemical Industry CO., LTD)

Chair: Masaaki Tokuda (Kagawa University, Japan)
Kunihiro Kishida
Department of Science and Technology on Food Safety, Kindai University, Japan.

Luncheon Seminar5

Talk in Japanese【Room I】5F, Conference Center

March 29, Fri., 12:20-13:20
LS5

Functional imaging of marmoset visual cortex(Co-sponsored by NIKON INSTECH CO., LTD.)

LS5-1

Functional imaging of marmoset visual cortex
Kenichi Ohki

Department of Physiology, Graduate School of Medicine, The University of Tokyo, Japan

LS5-2

Next generation confocal microscope system “A1R HD25”
Tadayoshi Ogura

NIKON INSTECH CO., LTD. Bioscience Sales Division, JapanDAY 2

Chair: Misuzu Nakajima (NIKON INSTECH CO., LTD., Japan)

Technical Workshop1

Talk in Japanese【Room F】5F, Conference Center

March 29, Fri., 12:20-13:20
TW1

Cutting edge of clinical rehabilitation for the paresis to reduce theburden on patients; Repetitive Facilitative Exercise combined withvibratory, electrical, magnetic stimulation and Robotics(Co-sponsored by YASKAWA ELECTRIC CORPORATION)

Chairs: Seiji Etoh (Graduate School of Medical and Dental Sciences, Kagoshima University, Japan)

Yong Yu (Graduate School of Science and Engineering, Kagoshima University, Japan)

TW1-1

Repetitive Facilitative Exercise combined with neuromuscularelectrical stimulation and vibratory stimulation for the upper
hemiplegic extremity
Tomokazu Noma

Department of Rehabilitation, Faculty of Health Sciences, Nihon Fukushi University,
Japan

TW1-2

Repetitive Facilitative Exercise combined with transcranial magnetic
stimulation
Seiji Etoh

Department of Rehabilitation and Physical Medicine, Graduate School of Medical and
Dental Sciences, Kagoshima University, Japan

TW1-3

Development of Hemiplegic Limbs Rehabilitation Devices Based on
Repetitive Facilitation Exercise
Yong Yu

Department of Mechanical Engineering, Graduate School of Science and Engineering,Kagoshima University, JapanGAKUSAI (interdisciplinary) Seminar【Room H】5F, Conference Center

March 29, Fri., 12:20-13:20
GAKUSAI Frontiers of Plasma Biology(Co-sponsored by Department of Plasmabio Science, Center for Novel Science Initiatives(CNSI), National Institutes of Natural Sciences (NINS))

Moderator: Motohiro Nishida (National Institute for Physiological Sciences (Exploratory Reserch
Center on Life and Living Systems), National Institutes of Natural
Sciences, Japan)

GAKUSAI-1	
Future Medicine and Innovation for Agriculture and Fisheries

Opened by Low-temperature Plasma Sciences
Masaru Hori

Center for Low-temperature Plasma Sciences, Nagoya University, Japan

Meet the Lecturers【Room M】3F, Exhibition Hall

March 29, Fri., 15:10-16:40
The Secret of High-Impact Research(Committee of the PSJ)

Organizers: Kaori Yamaguchi (International University of Health and Welfare)

Makoto Wada (Research Institute of National Rehabilitation Center for Persons with
Disabilities)

Lecturers: Linda B. Buck
Fred Hutchinson Cancer Research Center, USA

Hideyuki Okano
Keio University, Japan[overview]
This is an event for young physiologists and students. At the event, great scientists who
have great achievement in the field of physiology give participants their episodes about
the big findings, lab set-up, grant application and so on. The event consists of three parts;
topic providing from young researchers, Q&A with great scientists (lecturers answer toquestions from young scientists) and discussion with participants (lecturers and several
young scientists). Some questions are widely collected from young researchers throughSNS and so on in advance and some questions are received from participants at the venue
instantly.
We expect interaction with great scientists encourages young scientists who plan to havetheir own labs in the future.

Educational Lecture1
March 29, Fri., 8:00-8:40
EDL1
EDL1-1

Talk in Japanese【Room D】4F, Conference Center

Regulation of the autonomic functions
Regulation of the autonomic functions
Mieko Kurosawa

Center for Medical Science, International University of Health and WelfareThis lecture provides the credit in the qualification update for Physiology
Educator accredited by Physiological Society of Japan.

DAY 2

Planning and Management: Association of Young Researchers of Physiology

Poster (The 1st Poster Presentation Day)
March 29, Fri., 13:20-14:10/14:10-15:00

1F, Exhibition Hall

PSJ Awards
20th Promotion Award of the Physiological Society of Japanfor Young Scientists
AP-1

Chronic stress causes excessive aggression by altering synaptic
actin dynamics in the mPFC
Hirobumi Tada1,2), Takuya Takahashi2)
1
2

AP-2

Section of Neuroendocrinology, National Center for Geriatrics and Gerontology, Japan,
Department of Physiology, Yokohama City University

Characterization of the secondary auditory field in the mouse auditory
cortexHiroaki Tsukano

Department of Neurophysiology, Brain Research Institute, Niigata University, Japan

9th Hiroshi and Aya Irisawa Memorial Promotion Award
for Young Physiologists:
Section of channel and transporter
AP-3

Cytoplasmic conformational changes of VSP detected by voltage
clamp fluorescence spectroscopy
Akira Kawanabe, Tomoko Yonezawa, Yasushi Okamura
Graduate School of Medicine, Osaka University, Japan

AP-4

Interaction of junctophilins and the CaV1.1 is essential for the skeletal
muscle contraction
Tsutomu Nakada

Department of Molecular pharmacology, Shinshu University School of Medicine, Japan

9th Hiroshi and Aya Irisawa Memorial Promotion Award
for Young Physiologists:
Section of heart and circulatory system
AP-5

Physiological and pathophysiological significance of TRPC3-Nox2
coupling in the heart
Takuro Numaga-Tomita1,2,3), Tsukasa Shimauchi4,5), Naoyuki Kitajima4),
Akiyuki Nishimura2,4), Motohiro Nishida1,2,3,4)

Department of Creative Research, Exploratory Research Center on Life and Living
Systems: ExCELLS, National Institutes of Natural Sciences, Japan, 2National Institute forPhysiological Sciences (NIPS), National Institutes of Natural Sciences, 3School of life
sciences, SOKENDAI, 4Graduate School of Pharmaceutical Sciences, Kyushu University,
5
Graduate School of Medical Sciences, Kyushu University
1

PSJ Awards

9th Aya Irisawa Memorial Promotion Award
for Excellence by Women Physiologists
AP-6

Microglia permit climbing ﬁber pruning by promoting synaptic
inhibition in the developing cerebellum
Hisako Nakayama

Department of Physiology, School of Medicine, Tokyo Women's Medical University, 8-1,
Kawada-cho, Sinjuku-ku, Tokyo, Japan

AP-7

Inhibition of ghrelin-induced feeding in rats by treatment with a novel
orexin receptor antagonist
Mariko So1,2), Hirofumi Hashimoto2,4), Reiko Saito2,3), Yukiyo Yamamoto3),
Yasuhito Motojima2), Hiromichi Ueno2), Satomi Sonoda2),
Mitsuhiro Yoshimura2), Takashi Maruyama2), Koichi Kusuhara3),
Yoichi Ueta2)

Department of Health and Nutritional Care, Faculty of Medical Science, University of
East Asia, Shimonoseki 751-0807, Japan, 2Department of Physiology, School of
Medicine, University of Occupational and Environmental Health, 1-1 Iseigaoka,
Yahatanishi-ku, Kitakyushu 807-8555, Japan, 3Department of Pediatrics, School of
Medicine, University of Occupational and Environmental Health, Kitakyushu 807-8555,
Japan, 4Department of Regulatory Physiology, Dokkyo Medical University,
880 Kitakobayashi, Mibu 321-0293, Japan.
1

AP-8

Hypotonicity-induced cell swelling activates TRPA1

Fumitaka Fujita1,2,3), Kunitoshi Uchida4), Yasunori Takayama 1,5),
Yoshiro Suzuki 1,5), Masayuki Takaishi1,6), Makoto Tominaga1,5)

1
Division of Cell Signaling, National Institute for Physiological Sciences, Japan, 2Basic
Research Institute, Mandom Corp., Japan, 3Laboratory of Advanced Cosmetic Science,
Graduate School of Pharmaceutical Sciences, Osaka University, Japan, 4Departments ofPhysiological Science and Molecular Biology and Morphological Biology, Fukuoka
Dental College, Japan, 5Thermal Biology Group, Exploratory Research Center on Lifeand Living Systems, Japan; 6Product Assurance Division, Mandom Corp., Japan

9th Hiroshi and Aya Irisawa Memorial Award for Excellent Papers on Research in
Circulation in The Journal of Physiological Sciences
AP-9

Epac activation inhibits IL-6-induced cardiac myocyte dysfunction

Huiling Jin1), Takayuki Fujita1), Meihua Jin1,2), Reiko Kurotani1,3),
Yuko Hidaka1), Wenqian Cai1), Kenji Suita1), Rajesh Prajapati1), Chen Liang 1),
Yoshiki Ohnuki4), Yasumasa Mototani4), Masanari Umemura1),
Utako Yokoyama1), Motohiko Sato1,5), Satoshi Okumura1,4),
Yoshihiro Ishikawa1)
Cardiovascular Research Institute, Yokohama City University Graduate School of
Medicine, Japan, 2 Department of Cardiac Physiology, National Cerebral andCardiovascular Center Research Institute, Japan, 3 Biochemical Engineering, Faculty ofEngineering, Yamagata University, Japan, 4 Department of Physiology, Tsurumi
University School of Dental Medicine, Japan, 5 Department of Physiology, Aichi Medical
University, Japan
1

PSJ Awards

DAY 2

9th Hiroshi and Aya Irisawa Memorial Award
for Excellent Papers
in The Journal of Physiological Sciences

★Young Scientist Travel Award, ★★Young Scientist Travel Award & Masao Ito Memorial Award

Skeletal muscle & locomotion (1)1P-001Analysis of junctophilin2 knock out zebrafish
Souhei Sakata, Fumihito Ono

Department of Physiology, Division of Life Sciences, Faculty of Medicine, Osaka Medical
College, Japan

1P-002

Evaluation of muscle contraction by electromyogram and sonography
Masafumi Katayama

International University of Health and Welfare, Japan

1P-003

Muscle representations in spinal motor circuitry in intact humans andan individual with SCI
Toshiki Tazoe1), Koichi Iwatsuki2), Yukio Nishimura1)

Neural Prosthesis Project, Department of Dementia and Higher Brain Function, Tokyo
Metropolitan Institute of Medical Science, Japan, 2Senbokujinnai Hospital

1

1P-004Generation of a transgenic zebrafish for monitoring murf1 expression
Genri Kawahara, Mami S Nakayashiki, Yukiko K Hayashi

Department of Pathophysiology, Tokyo Medical University, Japan

1P-005

Acetylcholinesterase inhibitor accelerates muscle differentiation in
C2C12 myoblasts

Hiroshi Todaka1), Mikihiko Arikawa2), Tatsuya Noguchi3), Atsushi Ichikawa1),
Takayuki Sato1)

1
Dept Cardiovasc Control, Kochi Med Sch, Japan, 2Dept Biol Sci, Fac Sci Tech, Kochi Univ,
Japan, 3Dept Med Geriatr, Kochi Med Sch, Japan

1P-006

Emerin deficiency exacerbates skeletal muscle pathology in
LmnaH222P/H222P mutant mice
Eiji Wada, Megumi Kato, Kaori Yamashita, Yukiko K Hayashi
Department of Pathophysiology, Tokyo Medical University, Japan

1P-007

Cell surface flip-flop of phosphatidylserine is critical for PIEZO1mediated myotube formation
Yuji Hara1,2), Masaki Tsuchiya1), Masaki Okuda1), Kotaro Hirano1),
Seiji Takabayashi1), Masato Umeda1)
Graduate School of Engineering, Kyoto University, Japan, 2AMED, PRIME

1

1P-008

Role of Ror-family receptor tyrosine kinases in the skeletal muscle

Koki Kamizaki1), Ayano Yamamoto1), Ryosuke Doi1), Motoi Kanagawa2),
Tatsushi Toda2), Akiyoshi Uezumi3), So-Ichiro Fukada4), Mitsuharu Endo1),
Yasuhiro Minami1)

Division of Cell Physiology, Department of Physiology and Cell Biology, Graduate
School of Medicine, Kobe University, Japan, 2Division of Neurology/Molecular Brain
Science, Graduate School of Medicine, Kobe University, Japan, 3Department of GeriatricMedicine, Tokyo Metropolitan Institute of Gerontology, Japan, 4Laboratory of Molecular
and Cellular Physiology, Graduate School of Pharmaceutical Sciences, Osaka University,Japan
1

1P-009Bereitschaftspotential of the interference
distribution and finger movement timing

betweenattention

Daisuke Hirano1,2), Daisuke Jinnai1,3), Hana Nozawa1,3),
Takamichi Taniguchi1,3)
Graduate School of Health and Welfare Sciences, International University of Health andWelfare, Japan, 2Department of Occupational Therapy, School of Health Sciences at

1

Skeletal muscle & locomotion (1)Narita, International University of Health and Welfare, 3Department of Occupational
Therapy, School of Health Sciences, International University of Health and Welfare

1P-010Control of Keber’s valve at rest, foot extension and retraction of theclam Nodularia douglasiae
Yoshiteru Seo1), Yoshie Imaizumi-Ohashi1), Mika Yokoi-Hayakawa1),
Eriko Seo2)

Department of Regulatory Physiology, Dokkyo Medical University School of Medicine,Japan, 2Department of Marine Ecosystem Dynamics, Division of Marine Life Science,
Atmosphere and Ocean Research Institute, The University of Tokyo, Japan
1

Suppressive Activity of Chondroitin Sulfate on Nitric Oxide Production
by Knee Synoviocytes In Vitro
Takayuki Okumo1), Kazuhito Asano3), Hideshi Ikemoto1), Mana Tsukada1),
Shi-Yu Guo1), Koji Kanzaki2), Tadashi Hisamitsu1), Masataka Sunagawa1)

1
Department of Physiology, School of Medicine, Showa University, Japan, 2Departmentof Orthopaedic Surgery, Showa University Fujigaoka Hospital, Japan, 3Department of
Physiology, School of Nursing and Rehabilitation Science, Showa University, Japan

1P-012

Upregulation of osteclastogenic markers and impaired bone
microstructure in hypertensive rats

Wacharaporn Tiyasatkulkovit1,3), Worachet Promruk2,3),
Aniwat Sawangsalee1,3), Sirawich Intarapanich1,3), Jirawan Thongbunchoo2,3),
Kwanchit Chaimongkolnukul4), Kanchana Kengkoom4),
Nattapon Panupinthu 2,3), Narattaphol Charoenphandhu2,3,5,6)
Department of Biology, Faculty of Science, Chulalongkorn University, Thailand,
Department of Physiology, Faculty of Science, Mahidol University, Thailand, 3Center ofCalcium and Bone Research (COCAB), Faculty of Science, Mahidol University, Thailand,
4
National Laboratory Animal Center, Mahidol University, Thailand, 5Institute of Molecular
Biosciences, Mahidol University, Thailand, 6The Academy of Science, The Royal Societyof Thailand, Thailand
12

1P-013

Immature network function of the adult lumbosacral cord by loss ofinterferon regulatory factor 8
Itaru Yazawa1,2), Yuko Yoshida4), Ryusuke Yoshimi3,4), Michael J O’Donovan2),
Keiko Ozato4)

Global Research Center for Innovative Life Science, Hoshi University School of
Pharmacy and Pharmaceutical Sciences, Japan, 2Lab. of Neural Control, National
Institute of Neurological Disorders and Stroke, National Institutes of Health, USA,3
Department of Stem Cell and Immune Regulation, Yokohama City University Graduate
School of Medicine, Japan, 4Lab. of Molecular Growth Regulation, National Institute ofChild Health and Human Development, National Institutes of Health, USA
1

Exercise (1)1P-014

Exercise is better than caloric restriction regarding improving
fatigability in muscle of obese rats
Sintip Pattanakuhar1), Wissuta Sutham2,3), Jirapas Sripetchwandee2,3),
Wanitchaya Minta2,3), Duangkamol Mantor2,3), Siripong Palee2,3),
Wasana Pratchayasakul2,3), Nipon Chattipakorn2,3),
Siriporn C. Chattipakorn2,4)

Department of Rehabilitation Medicine, Chiang Mai University, Thailand,
Neurophysiology Unit, Cardiac Electrophysiology Research and Training Center,
Faculty of Medicine, Chiang Mai University, Thailand, 3Cardiac Electrophysiology Unit,
Department of Physiology, Faculty of Medicine, Chiang Mai University, Thailand,
4
Department of Oral Biology and Diagnostic Science, Faculty of Dentistry, Chiang Mai
University, Thailand
1
2

Skeletal muscle & locomotion (1)/Exercise (1)DAY 2

1P-011

1P-015

Effects of Hypoxia on Skeletal Muscle Molecular Adaptations to
Heavy Resistance Training
Aaron Petersen1), Jackson Fyfe2), Mathew Inness1,3), Lewan Parker2),
Francois Billaut4), Robert Aughey1)

1Institute for Health and Sport, Victoria University, Australia, 2School of Exercise andNutrition Sciences, Deakin University, Australia, 3Western Bulldogs Football Club,
Australia, 4Département de Kinesiologie, Université Laval, Canada

1P-016

Enriched environment attenuates hindlimb dysfunction in neonatal
white matter injury model
Naoki Tajiri1), Atsunori Hattori1), Yoshitomo Ueda1), Shino Ogawa1,2),
Akimasa Ishida1), Takeshi Shimizu1, Hideki Hida1

Department of Neurophysiology & Brain Science, Graduate School of Medical Sciences& Medical School, Nagoya City University, Japan, 2Department of Obstetrics andGynecology, Graduate School of Medical Sciences & Medical School, Nagoya City
University, Japan1

1P-017

Role of dopaminergic function in septum on exercise efficiency

Tetsuya Shiuchi, Takuya Masuda, Noriyuki Shimizu, Sachiko Chikahisa,
Hiroyoshi Sei
Department of Integrative Physiology, Tokushima University Graduate School, Japan

1P-018Enhanced muscle afferent responses to mechanical/chemical stimuli
in type 2 diabetic rats in vitro
Rie Ishizawa1), Norio Hotta2), Gary A Iwamoto1), Han-Kyul Kim1),
Wanpen Vongpatanasin1), Jere H Mitchell1), Scott A Smith1), Masaki Mizuno1)

1
University of Texas Southwestern Medical Center, United States, 2Chubu University,Japan

1P-019Sex difference in mitochondrial Ca2+ handling properties in mouseskeletal muscle
Daiki Watanabe, Koji Hatakeyama, Hiroaki Eshima, Ryo Ikegami,
Yutaka Kano

Department of Engineering Sciences, University of Electro-communications, Japan

1P-020Enhanced cerebro-cardiovascular responses before voluntary
cycling in physically fit men
Kazumasa Manabe1,2), Shizue Masuki1,2), Koji Uchida1), Yu Takeda1),
Hiroshi Nose1,2)

Department of Sports Medical Sciences, Shinshu University Graduate School of
Medicine, Japan, 2Institute for Biomedical Sciences, Shinshu University, Japan1

1P-021

Unloading-induced sarcopenia in relation to mitochondrial disorder inskeletal muscle of old rats
Hideki Yamauchi, Shigeru Takemori

Div of Phys Fitness, Dept of Mol Physiol, The Jikei Univ Sch Med, Japan

1P-022The effect of warm/cool stimulus to forearm/hand on brachial arteryblood flow during leg exercise
Yoshiyuki Fukuba1), Saki Namura1), Marina Morimoto1), Kohei Miura1),
Hideaki Kashima1), Anna Oue2)

Department of Exercise Science and Physiology, School of Health Sciences, Prefectural
University of Hiroshima, Japan, 2Faculty of Food and Nutritional Sciences, Toyo
University, Japan
1

Exercise (1)1P-023

Timing of nutrient intake after mild exercise: effects of gastrointestinal
activity in humans
Hideaki Kashima1), Saori Kamimura1), Masako Yamaoka Endo1),
Kohei Miura1,2), Akira Miura1), Yoshiyuki Fukuba1)

Department of Exercise Science and Physiology, School of Health Sciences, Prefectural
University of Hiroshima, Japan, 2Department of Health and Nutrition, Hiroshima Shudo
University, Japan1

Effects of continuous exercise with vocalization on the oxygen
dissociation states in muscles
Hajime Arikawa1), Toshio Matsuoka1), Teppei Takahashi2),
Tomoyoshi Terada3), Seiichi Era4)

Faculty of Sports and Health Sci, Chubu Gakuin Univ, Japan, 2Dept Oral and Maxillofacial
Surgery, Gifu Prefectural Gero Hospital, Japan, 3United Graduate School of Drug
Discovery and Medical Information Sciences, Gifu Univ, Japan, 4Dept of General Internal
Medicine, Gifu Univ, Japan1

1P-025The salivary 11β-HSD2 activities is beneficial for continuous strength
exercises in elderly people
Miyako Mochizuki1), Noboru Hasegawa2)

Kyoto Bunkyo Junior College, Japan, 2Department of Health and Medical Sciences,
Ishikawa Prefectural Nursing University, Japan1

1P-026The differential dynamics of brachial artery and forearm skin bloodflows during leg cycle exercise
Kohei Miura1), Ayaka Kondo2), Yuka Kikugawa2), Masako Y Endo2),
Hideaki Kashima2), Anna Oue3), Yoshiyuki Fukuba2)

Faculty of Health Sciences, Department of Health and Nutrition, University ofHiroshima Shudo, Japan, 2Department of Exercise Science and Physiology, School of
Health Sciences, Prefectural University of Hiroshima, Japan, 3Faculty of Food andNutritional Sciences, Toyo University, Japan1

1P-027

Molecular hydrogen increases acetone excretion and changes lipid
metabolism during exercise
Amane Hori, Ryota Masuda, Masatoshi Ichihara, Hisayoshi Ogata,
Takaharu Kondo, Norio Hotta
Chubu University, Japan

1P-028Combining Acute Exercise With Insulin Treatment increase Type 1
Diabetic Liver Antioxidant Capacity
Hei-Man Yuen, Ting-Wen Lin, Shiow-Chwen Tsai
Institute of Sports Sciences, University of Taipei, Taiwan

1P-029Longitudinal changes of trunk skeletal muscle characteristics inJapanese elderly males and females
Noriko Ishiguro Tanaka1), Madoka Ogawa1,2), Hisashi Maeda1,2),
Akito Yoshiko3), Aya Tomita3), Ryosuke Ando4), Hiroshi Akima1)

Research Center of Health Physical Fitness and Sports, Nagoya University, Japan,
Japan Society for the Promotion of Science, Japan, 3School of International LiberalStudies, Chukyo University, Japan, 4Japan Institute of Sports Science, Japan1
2

1P-030Relationship between occlusal balance and agility in Japanese elite
female junior badminton players
Mutsumi Takahashi1,2), Yogetsu Bando2,3), Yoshihide Satoh1)

Department of Physiology, The Nippon Dental University School of Life Dentistry at
Niigata, Japan, 2Division of Medical Science Research, The Japan Schoolchildren

1

Exercise (1)DAY 2

1P-024

Badminton Federation, Japan, 3BANDO Dental Clinic, Japan

1P-031

Estimation of maximal oxygen uptake from oxygen uptake efficiency
slope by leg or arm ergometer
Reizo Baba, Norio Hotta, Hisako Urai, Hisayoshi Ogata, Yukiko Okamura
College of Life and Health Sciences, Chubu University, Japan

1P-032

Effect of low-volume high-intensity interval exercise on post-exercise
inhibitory control
Takeshi Sugimoto1), Tadashi Suga1), Hayato Tsukamoto2), Daichi Tanaka1),
Saki Takenaka1), Kento Shimoho1), Tadao Isaka1), Takeshi Hashimoto1)

Faculty of Sport and Health Science, Ritsumeikan University, Japan, 2Faculty of Life
Sciences and Education, University of South Wales

1

1P-033Atrioventricular nodal function during dynamic exercise in elite
endurance athletes
Makoto Takahashi1), Tomoko Nakamoto1), Shigemitsu Niihata2),
Kanji Matsukawa1)
1
2

1P-035

Graduate School of Biomedical and Health Sciences, Hiroshima University, Japan,
Faculty of Welfare and Health, Fukuyamaheisei University

The influence of aerobics dance exercise on energy intake, appetite,and mood in young women
Yuki Aikawa1), Yusuke Takagi2), Minori Horiba3)
1

1P-036

Tsu City College, Japan, 2Nara University of Education, 3Nagoya University of The Arts

Shortening velocity of knee extensor in frog in vivo

Yoshiki Ishii1), Yuki Yamanaka1), Tomohito Mizuno1), Nobuaki Sasai2),
Toshie Nagare1), Teizo Tsuchiya3)

1
Faculty of Health Care Sciences, Himeji Dokkyo University, Japan, 2Faculty of Health
Science, Suzuka University of Medical Science, Japan, 3Faculty of Science, Kobe
University, Japan

1P-037CO2-water bath promotes a recovery from the muscle fatigue inducedby high intensity exercise
Noriyuki Yamamoto1), Tadashi Wada2), Fumiko Takenoya3),
Masaaki Hashimoto4)

Department of Health Science, Japanese Red Cross Hokkaido College of Nursing,Japan, 2Faculty of Science and Technology, Kokushikan University, 3Department ofPharmacy, Hoshi University, 4Physiology Laboratory, Canter for Medical Education,
Teikyo University of Science1

1P-038How does voluntary exercise frequency affect cardiac function indilated cardiomyopathy model mice?
Masami Sugihara1), Ryo Kakigi3), Takashi Murayama2), Takashi Miida1),
Takashi Sakurai2), Sachio Morimoto4), Nagomi Kurebayashi2)

1
Department of Clinical Laboratory, Juntendo University, Japan, 2Department of
Phamacology, Juntendo University, Japan, 3Department of Physiology(II), Juntendo
University, Japan, 4Department of Health Sciences at Fukuoka, International University
of Health and Welfare, Japan

1P-039Effect of lower body positive pressure and walking on fluid turnover inhuman legs
Satoshi Matsuo, Felix Ojeiru Ezomo, Noriko Matsuo
Division of Adaptation Physiology, Tottori University, Japan

Exercise (1)1P-040

Changes in weight bearing index (WBI) before and after skyrunningin Mt. Fuji
Hiroto Tsujikawa1), Koki Nagatsu2), Junichi Nagasawa3), Yutaka Iwaihara2),
Shinichi Murata2), Shino Sasaki1), Koji Sugiyama2)

Circulation & Respiration: Cardiac Physiology (1)1P-041

Electrophysiological analyses of multi-ion channel blockers in hiPSCCMs sheets with MEA system
Hiroko Izumi-Nakaseko1,2), Atsuhiko T Naito1,2), Yuko Sekino3),
Mihoko Hagiwara-Nagasawa1), Ai Goto2), Koki Chiba2), Yasunari Kanda4),
Atsushi Sugiyama1,2)

Department of Pharmacology, Faculty of Medicine, Toho University, Japan,
Department of Pharmacology, Toho University Graduate School of Medicine, Japan,
3
Endowed Laboratory of Human Cell-based Drug Discovery, Graduate School of
Pharmaceutical Sciences, The University of Tokyo, Japan, 4Division of Pharmacology,
National Institute of Health Sciences, Japan1
2

1P-042A CMOS camera depicted the excitation spread during arrhythmia in
an isolated rat atrial preparation
Tetsuro Sakai

Department of Systems Physiology, University of The Ryukyus Graduate School of
Medicine, Japan

1P-043

Potential link between Ca2+-activated cation TRPM4 channels and Ist
in mouse cardiac pacemaker cells
Futoshi Toyoda, Wei-Guang Ding, Hiroshi Matsuura

Department of Physiology, Shiga University of Medical Science, Japan

1P-044

Functional role of delayed rectifier K+ current in the automaticity of
pulmonary vein cardiomyocytes
Xinya Mi, Wei-Guang Ding, Yingnan Li, Hiroshi Matsuura
Department of Physiol, University of Shiga Univ. Med. Sci., Japan

1P-045

Pacemaking ion channel remodelling underlies chronic exerciseinduced atrioventricular block
Shu Nakao1,3), Alicia D’Souza1), Pirtro Mesirca2), Tariq Trussell1), Min Zi1),
Sunil JRJ Logantha1), Elizabeth J Cartwright1), Matteo E Mangoni2),
Halina Dobrzynski1), Mark R Boyett1)

1
Division of Cardiovascular Sciences, University of Manchester, UK, 2Département dePhysiologie, Université de Montpellier, France, 3Department of Biomedical Sciences,
Ritsumeikan University, Japan

1P-046

Cardiac Iron Overload: Impacts on Cellular Electrophysiology andCalcium Handling
Natthaphat Siri-Angkul1,2,3), Richard Gordan3), Suwakon Wongjaikam1,2),Nadezhda Fefelova3), Judith K. Gwathmey3), Siriporn C. Chattipakorn1,4),
Nipon Chattipakorn1,2), Lai-Hua Xie3)

Cardiac Electrophysiology Research and Training Center, Faculty of Medicine, Chiang
Mai University, Thailand, 2Cardiac Electrophysiology Unit, Department of Physiology,
Faculty of Medicine, Chiang Mai University, Thailand, 3Department of Cell Biology andMolecular Medicine, Rutgers University - New Jersey Medical School, USA, 4Department
1

Exercise (1)/Circulation & Respiration: Cardiac Physiology (1)

DAY 2

1
Faculty of Health Science and Nursing, Juntendo University, Japan, 2Faculty of
Education-Physical and Health Education, Shizuoka University, Japan, 3College of
Humanities and Sciences, Nihon University, Japan

of Oral Biology and Diagnostic Sciences, Faculty of Dentistry, Chiang Mai University,
Thailand

1P-047

Species difference of the hyperpolarized-activated current inpulmonary vein cardiomyocytes
Daichi Takagi1), Yosuke Okamoto1), Takayoshi Ohba1), Hiroshi Yamamoto2),
Kyoichi Ono1)

Dept. Cell Physiol., Akita Univ. Grad. Sch. Med., Japan, 2Dept Cardiovas. Surg., Akita Univ.
Grad. Sch. Med., Japan1

1P-048The mitochondrial Na+-Ca2+ exchanger is involved in automaticity ofmurine sinoatrial nodal cells
Yukari Takeda, Ayako Takeuchi, Satoshi Matsuoka

Department of Integrative & Systems Physiology, Faculty of Medical Sciences, Universityof Fukui, Japan

1P-049Low T-tubule density is related with vulnerability of sympathetic atrial
arrhythmia
Jieun An, Ami Kim, Tong Mook Kang

Department of Physiology, Sungkyunkwan Univeristy, Korea

1P-050Effect of Myocyte Mechanical Properties on Transmural Distributionof Stress and Energy Consumption
Shiro Kato, Kumiko Tamura, Akira Amano

Department of Bioinformatics, Graduate School of Life Science, University of
Ritsumeikan, Japan

1P-051D-galactose worsens cardiac function via aggravating mitochondrial
dysfunction in obese rats
Cherry Bo-Htay1,2,3), Thazin Shwe1,2,3), Krekwit Shinlapawittayatorn1,2,3),
Siripong Palee1,3), Siriporn C Chattipakorn1,3,4), Nipon Chattipakorn1,2,3)

Cardiac Electrophysiology Research and Training Center, Faculty of Medicine, Chiang
Mai University, Thailand, 2Cardiac Electrophysiology Unit, Department of Physiology,
Faculty of Medicine, Chiang Mai University, Thailand, 3Center of Excellence in Cardiac
Electrophysiology, Chiang Mai University, Thailand, 4Department of Oral Biology and
Diagnostic Science, Faculty of Dentistry, Chiang Mai University, Thailand
1

1P-052

Drug Effect Estimation System that Uses Cardiac Action Potential
Waveforms
Maho Yamamoto1), Kazuki Okumura2), Yukiko Himeno2), Akira Amano2)

Graduate School of Life Sciences, Ritsumeikan University, Japan, 2Department of
Bioinformatics, College of Life Sciences, University of Ritsumeikan, Japan1

1P-053

Acute Overstretch Causes Abrupt Inner Mitochondrial Collapsing of
Rat Papillary Muscles
Naritomo Nishioka1,2), Yoichiro Kusakari1), Jun Tanihata3),
Susumu Minamisawa1,3)

Department of Cell Physiology, The Jikei University School of Medicine, Japan,
Department of Cardiac Surgery, The Jikei University School of Medicine, Japan,
3
Division of Aerospace Medicine, Department of Cell Physiology, The Jikei University
School of Medicine, Japan1
2

1P-054PCSK9 Inhibitor Attenuates Cardiac and Mitochondrial Dysfunction
in Obese-Insulin Resistant Rats
Patchareeya Amput1,2,3), Siripong Palee1,3), Busarin Arunsak1,2,3),
Wasana Pratchayasakul1,2,3), Thidarat Jaiwongkam1,3),
Siriporn C Chattipakorn1,3,4), Nipon Chattipakorn1,2,3)
Circulation & Respiration: Cardiac Physiology (1)Cardiac Electrophysiology Research and Training Center, Faculty of Medicine, Chiang
Mai University, Thailand, 2Cardiac Electrophysiology Unit, Department of Physiology,
Faculty of Medicine, Chiang Mai University, Thailand, 3Center of Excellence in Cardiac
Electrophysiology Research, Chiang Mai University, Thailand, 4Department of Oral
Biology and Diagnostic Sciences, Faculty of Dentistry, Chiang Mai University, Thailand
1

1P-055

Evaluating the Role of Individual Types of Ca2+ Channels in the
Sinoatrial Node Pacemaker Cell Model
Graduate School of Life Sciences, Bioinformatics Course, University of Ritsumeikan,
Japan, 2Shiga University of Medical Science, Japan1

1P-056

Experimental Autoimmune Myocarditis (EAM) Model in NonhumanPrimates
Shunya Nakayama1,2), Hiroshi Koie1), Yuki Ishii1,2, Chungyu Pai1,2),
Yasuyo Ito-Fujishiro1,2), Kiichi Kanayama1), Yoshiko Munesue3),
Tadashi Sankai2), Yasuhiro Yasutomi2), Naohide Ageyama2)

Laboratory of Veterinary Physiology, Nihon University, Japan, 2Tsukuba Primate
Research Center, NIBIOHN, Japan, 3The Corporation for Production and Research ofLaboratory Primates, Japan1

1P-057

Physiological role of TRPC6 upregulation in hyperglycemia-exposed
mice hearts
Sayaka Oda1,2), Takuro Numaga-Tomita1,2), Akiyuki Nishimura3),
Motohiro Nishida1,2,3)

Division of Cardiocirculatory Signaling, National Institute for Physiological Sciences(Exploratory Research Center on Life and Living Systems), National Institutes of Natural
Sciences, Japan, 2Department of Physiological Sciences, SOKENDAI (School of Life
Science, The Graduate University for Advanced Studies), 3Department of Translational
Pharmaceutical Sciences, Graduate School of Pharmaceutical Sciences, Kyushu
University
1

1P-058

IL-6 may have protective roles in Lmna-related cardiomyopathy
Megumi Kato1), Mizuyo Kojima2), Kaori Yamashita1), Eiji Wada1),
Yukiko Hayashi1)

1
Department of Pathophysiol, Grad Sch Med, Tokyo Medical Univ, Japan, 2Sopport
Center of Medical Doctors and Researchers, Tokyo Medical University, Japan

1P-059Sonic hedgehog signaling regulates the mammalian cardiac regenerative response
Hiroyuki Kawagishi1,2,3), Jianhua Xiong2), Mitsuhiko Yamada3),
Toren Finkel2,4)Institute for Biomedical Sciences, Shinshu University, Japan, 2Center for Molecular
Medicine, National Heart, Lung and Blood Institute/NIH, USA, 3Department of Molecular
Pharmacology, Shinshu University School of Medicine, Japan, 4Aging Institute of UPMC
and The University of Pittsburgh, USA
1

1P-060Analysis of Diabetic Cardiomyopathy with type 2 Diabetes Mellitus in
Nonhuman Primate
Yuuki Ishii1,2), Shunya Nakayama1,2), Hiroshi Koie1), Chungyu Pai1,2),
Yasuyo Ito-Fujishiro1,2), Kiichi Kanayama1), Yoshiko Munesue3),
Tadashi Sankai2), Yasuhiro Yasutomi2), Naohide Ageyama2)

1
Laboratory of Veterinary Physiology, Nihon University, Japan, 2 Tsukuba Primate
Research Center, NIBIOHN, Japan, 3CPRLP, Japan

1P-061

Role of Cardiac Hormones in a Nonhuman Primate Model of Cardiac
DiseaseCirculation & Respiration: Cardiac Physiology (1)DAY 2

Yixin Zhang1), Yukiko Himeno1), Futoshi Toyoda2), Akira Amano1),
Akinori Noma1)

Chungyu Pai1,2), Hiroshi Koie1), Yuki Ishii1,2), Yasuyo Ito-Fujishiro1,2),
Kiichi Kanayama1), Yoshiko Munesue3), Tadashi Sankai2),
Yasuhiro Yasutomi2), Naohide Ageyama2)
Laboratory of Veterinary Physiology, Nihon University, Japan, 2Tsukuba Primate
Research Center, NIBIOHN, Japan, 3CPRLP, Japan1

1P-062

Activation of SIRT1 Attenuates Cardiac fibrosis via preventing
Endothelial-to-Mesenchymal Transition
Zhenhua Liu, Yanhong Zhang, Yongsheng Gong, Xu Li, Liping Han
Wenzhou Medical University, China

1P-063Insulin signaling deficiency is responsible for diastolic dysfunction ofdiabetic cardiomyopathy
Yoshinori Mikami1), Masanori Ito1), Shogo Hamaguchi2),
Shingo Murakami1,3), Taichiro Tomida1), Daisuke Ohshima1),
Iyuki Namekata2), Hikaru Tanaka2), Satomi Adachi-Akahane1)

1Department of Physiology, Faculty of Medicine, Toho University, Japan, 2Departmentof Pharmacology, Faculty of Pharmaceutical Sciences, Toho University, Japan, 3Facultyof Science and Engineering, Chuo University, Japan

1P-064

Vitamin B1 pretreatment prevents cardiac mitochondrial morphology
from ischemia/reperfusion injury
Yoichiro Kusakari1), Naritomo Nishioka1,2), Jun Tanihata1),
Susumu Minamisawa1)
1
2

1P-065

Department of Cell Physiology, The Jikei University School of Medicine, Japan ,Department of Cardiac Surgery, The Jikei University School of Medicine, Japan

Regulation of Orai1 in Angiotensin II-Induced Cardiac Hypertrophy
Mingxu Xie, Changbo Zheng, Xiaoqiang Yao

School of Biomedical Sciences, The Chinese University of Hong Kong, China

1P-066

Plasma Proteomic Analysis of Acute Myocardial Infarction in Young
AdultsNorbaiyah Mohamed Bakrim1), Aszrin Abdullah1),
Azarisman Shah Mohd Shah2), Norlelawati A Talib3),
Aida Nur Sharini Mohd Shah2), Jamalludin A Rahman4),
Noraslinda Muhamad Bunnori5), Siti Khairani Zainal Abidin6),
Mohd Yusri Idorus7)

Department of Basic Medical Sciences, Faculty of Medicine, International Islamic
University Malaysia, Kuantan, Malaysia, 2Department of Internal Medicine, Faculty of
Medicine, International Islamic University Malaysia, Malaysia, 3Department of Pathology
and Laboratory Medicine, Faculty of Medicine, International Islamic University Malaysia,
Malaysia., 4Department of Community Medicine, Faculty of Medicine, International
Islamic University Malaysia, Malaysia., 5Department of Biotechnology, Faculty of
Sciences, International Islamic University Malaysia, Malaysia, 6Hospital Tengku Ampuan
Afzan, Malaysia., 7Institute of Medical Molecular Biotechnology, Faculty of Medicine,
Malaysia
1

1P-067

Angiotensin-(1-5)-mediated cardioprotection via AT2R-PI3K-AkteNOS pathway
Byung Mun Park, Weijian Li, Suhn Hee Kim

Department of Physiology, Research Institute for Endocrine Sciences, Chonbuk
National University Medical School, Korea

1P-068

Palmitic Acid Contributes to the Development of Ca2+ Oscillations in
Adult Rat Cardiomyocyte
Yan-Jhih Shen1), Kun-Ta Yang2,3)

Circulation & Respiration: Cardiac Physiology (1)PhD Program in Pharmacology and Toxicology, School of Medicine, Tzu Chi University,
Taiwan, 2Department of Physiology, School of Medicine, Tzu Chi University, Taiwan,
3
Institute of Medical Sciences, Tzu Chi University, Taiwan
1

1P-069Insights into signaling mechanism of ANP receptor by x-ray crystal­lographyHaruo Ogawa, Masami Kodama
IQB, The University of Tokyo, Japan(AP-5)

Physiological and pathophysiological significance of TRPC3-Nox2
coupling in the heart
Takuro Numaga-Tomita1,2,3), Tsukasa Shimauchi4,5), Naoyuki Kitajima4),
Akiyuki Nishimura2,4), Motohiro Nishida1,2,3,4)

Department of Creative Research, Exploratory Research Center on Life and Living
Systems: ExCELLS, National Institutes of Natural Sciences, Japan, 2National Institute forPhysiological Sciences (NIPS), National Institutes of Natural Sciences, 3School of Life
Sciences, SOKENDAI, 4Graduate School of Pharmaceutical Sciences, Kyushu University,
5
Graduate School of Medical Sciences, Kyushu University
1

1P-071

Nuclear connectin novex-3 is essential for proliferation of hypoxic
fetal cardiomyocytes
Ken Hashimoto1), Aya Kodama1), Miki Sugino1), Tomoko Yobimoto1),
Takeshi Honda2), Akira Hanashima1), Yoshihiro Ujihara1), Satoshi Mohri1)

First Department of Physiology, Kawasaki Medical School, Japan, 2Department of
Cardiovascular Surgery, Kawasaki Medical School, Japan1

1P-072

Effect of autonomic nervous system on early and late repolarizationintervals in children
Hirofumi Kusuki1), Yuri Mizutani2), Yuka Tsuchiya1), Tadayoshi Hata1)

1
Graduate School of Health Science, Fujita Health University, Japan, 2Division of ClinicalLaboratory, Fujita Health University Hospital, Japan

1P-073

Pilocarpine but not Ach permeate the mouse footpads and induce
perspiration, sedation and arrhythmia
Shinichi Sato, Yosuke Okamoto, Kyoichi Ono

Department of Cell Physiology, Akita University, Japan

1P-074

Expression change of cytokine in principal organ during cardio­
pulmonary bypass
Yutaka Fujii1), Haruo Hanawa2)

Department of Clinical Engineering and Medical Technology, Niigata University of
Health and Welfare, Japan, 2Department of Health and Sports, Niigata University of
Health and Welfare

1

1P-075

Irregular division of the nucleus without cytokinesis in cardiac
progenitor cells of mouse heart
Ryo Fukunaga, Mariko Omatsu-Kanbe, Hiroshi Matsuura

Department of Physiology, Shiga University of Medical Science, Japan

1P-076

Usefulness of anti-arrhythmic drug therapy targeting cardiac adenylyl
cyclaseKenji Suita1, Takayuki Fujita2, Satoshi Okumura1, Yoshihiro Ishikawa2

Department of Physiology, Tsurumi University School of Dental Medicine, Japan,
Cardiovascular Research Institute, Yokohama City University Graduate School of
Medicine

1
2

1P-077

Stress intensity exhibited by E-PASS score and development of atrial
fibrillation
Circulation & Respiration: Cardiac Physiology (1)DAY 2

1P-070Takashi Kikuchi1), Takahide Kodama2), Masaki Ueno3), Minae Kamata1),
Yukimi Nakano1), Haruo Mitani2)
1
Department of Clinical Phygiology, Toranomon Hospital, Japan, 2CardiovascularCenter, Toranomon Hospital, Japan, 3Department of Gastroenterological Surgery,
Toranomon Hospital, Japan

1P-078Initiation of the heartbeat in rat embryonic heart precedes sarcomere
formation
Nobutoshi Ichise, Tatsuya Sato, Yoshinori Terashima, Mitsumasa Chiba,
Hiroya Yamazaki, Syunsuke Jimbo, Noritsugu Tohse

Department of Cellular Physiology and Signal Transduction, Sapporo Medical University,
Japan

1P-079Contribution of the rostroventral midbrain to movement-related
cardiovascular activation
Kei Ishii1), Ryota Asahara2), Nan Liang2), Hidehiko Komine1),
Kanji Matsukawa2)

Automotive Human Factors Research Center, National Institute of Advanced Industrial
Science and Technology, Japan, 2Department of Integrative Physiology, Graduate
School of Biomedical and Health Sciences, Hiroshima University, Japan1

1P-080Mechanism of augmentation of hydrogen sulfide-induced ANP
secretion in hypoxic condition
Weijian Li1), Lamei Yu2), Byung Mun Park1), Suhn Hee Kim1)

Department of Physiology, Research Institute for Endocrine Sciences, Chonbuk
National University Medical School, Korea, 2Department of Physiology, Binzhou Medical
University, China
1

Circulation & Respiration: Lung Physiology (1)1P-081

In vitro generation of goblet cell hyperplasia model using iPS cells
and cigarette smoking solution
Susumu Yoshie, Masao Miyake, Akihiro Hazama

Department of Cellular and Integrative Physiology, Fukushima Medical University,
Japan

1P-082

Pulmonary Hypertension Downregulated Mitochondria AssociatedMembrane Tethering Proteins In Rat
Shunsuke Baba, Satoko Shinjo, Yoshitaka Fujimoto, Mariko Okada,Toru Akaike, Yoichiro Kusakari, Susumu Minamisawa
Department of Cell Physiology, Jikei Medical University, Japan

1P-083NF- κB-mediated upregulation of miR-335-3p contributes to the
induction of hypoxic PAH in mice
Xiaofang Fan, Junming Fan, Hui Guang, Xiaoqiong Shan, Yongyu Wang,
Lianggang Hu, Yongsheng Gong
Institute of Hypoxia Medicine, Wenzhou Medical University, PR China

1P-084

The role of vascular smooth muscle NCX1 in the pathogenesis of
pulmonary arterial hypertension
Hideaki Tagashira1), Asahi Nagata1,2), Satomi Kita1,3), Tomo Kita1),
Sari Suzuki1), Kohtaro Abe4), Akinori Iwasaki2), Takahiro Iwamoto1)

Department of Pharmacology, Faculty of Medicine, Fukuoka University, Japan,
Department of General Thoracic, Breast and Pediatric Surgery, Faculty of Medicine,
Fukuoka University, Japan, 3Department of Pharmacology, Faculty of Pharmaceutical
Sciences, Tokushima Bunri University, Japan, 4Department of Cardiovascular Medicine,1
2

Circulation & Respiration: Cardiac Physiology (1)/Circulation & Respiration: Lung Physiology (1)Kyushu University Graduate School of Medical Sciences, Japan

1P-085

Inflammatory effects of menthol versus non-menthol cigarette smokeon the mouse lungs
Yu Ru Kou1), Tzong-Shyuan Lee2)

Department of Physiology, School of Medicine, National Yang-Ming University, Taiwan,
Graduate Institute and Department of Physiology, College of Medicine, National
Taiwan University, Taiwan

1
2

Nerve growth factor contributes laryngeal airway hyperreactivity inrats with intermittent hypoxia
Ping-Hsun Ou1), Yan-Jhih Shen2), Ching Jung Lai1)

Master Program in Medical Physiology, School of Medicine, Tzu Chi University, Taiwan,
PhD program in Pharmacology and Toxicology, School of Medicine, Tzu Chi University,
Taiwan1
2

1P-088Successful cigarette smoke extract-induced emphysema model
defined by histology and inflammation
Siriporn V Siriphorn1,3), Supitsara Thorsuwan1), Julalux Thongam1),
Poungpetch Hussarin1), Thanaporn Rungruang2), Sorachai Srisuma1)

Department of Physiology, Faculty of Medicine Siriraj Hospital, Mahidol University,
Thailand, 2Department of Anatomy, Faculty of Medicine Siriraj Hospital, Mahidol
University, Thailand, 3Faculty of Physical Therapy and Sport Medicine, Rangsit University,
Thailand1

Circulation & Respiration: Vascular Physiology (1)1P-089Functional Role of TRPC5 in Platelets

Zhuo Duan1), Lau Eva2), Lo Chun Yin1), Yao Xiao Qiang1)
1
2

1P-090School of Biomedical Sciences, The Chinese University of Hong Kong, Hong Kong,
Institute of Neuroscience, University of Louvain, Belgium

Decreased expression of KATP channel in human umbilical smoothmuscle during gestational diabetes
Won Sun Park, Ji Hye Jang, Mi Seon Seo

Department of Physiology, Kangwon National University School of Medicine, Korea

1P-091

Vildagliptin induces vasodilation via SERCA pump and Kv channel
activation in aortic smooth muscle
Mi Seon Seo, Won Sun Park

Department of Physiology, Kangwon National University School of Medicine, Korea

1P-092

Withdrawn

1P-093

Roles of K+ channels in synchronising spontaneous Ca2+ transients inmural cells of rectal arteriole
Retsu Mitsui, Hikaru Hashitani

Department of Cell Physiology, Nagoya City University Graduate School of Medical
Sciences, Japan

1P-094

Periodic assessment of (ET-1) and Nitric Oxide (NO) in hypertensive
disorders of pregnancy (HDP)
Hidayatul Radziah Ismawi1), Tariq Abd. Razak1), Nurjasmine Aida Jamani2),
Maizura Mohd Zainudin1)

Department of Basic Medical Sciences, Kulliyyah of Medicine, International Islamic
University Malaysia, 2Department of Family Medicine, Kulliyyah of Medicine,1

Circulation & Respiration: Lung Physiology (1)/Circulation & Respiration: Vascular Physiology (1)DAY 2

1P-086

International Islamic University Malaysia

1P-095

L-Cysteine’s carotid flow responses mapped in pre-sympathetic
areas of the rat ventral medulla
Yumi Takemoto

Physiology II, Biomedical Sciences Major, Graduate School of Biomedical and Health
Sciences, Hiroshima University, Japan

1P-096

Role of c-Abl/YAPY357 in integrin α5 activation in endothelial athe­rogenic responses
Bochuan Li, Jinlong He

Department of Physiology and Pathophysiology, Tianjin Medical University, China

1P-097

Different effects of α and β1 blockers on Beta in the elastic andmuscular arteries in rabbits
Shi-ichiro Katsuda1), Yuko Horikoshi2), Yuko Fujikura3), Akihiro Hazama1),
Tsuyoshi Shimizu4), Koji Shirai5)

Department of Cellular and Integrative Physiology, Fukushima Medical University
School of Medicine, Japan, 2Department of Laboratory Medicine, Fukushima Medical
University School of Medicine, Japan, 35th-year Medical Student, Fukushima Medical
University School of Medicine, Japan, 4Shimizu Institute of Space Physiology, Suwa
Maternity Clinic, Japan, 5Seijinkai Mihama Hospital, Japan1

1P-098

Angiopoietin-2 is released after vascular leak onset during
anaphylaxis in un- and anesthetized rats
Toshishige Shibamoto1), Mamoru Tanida1), Tao Zhang1,2), Wei Yang1,3),
Yuhichi Kuda1), Yasutaka Kurata1)

Department of Physiology 2, Kanazawa Medical University, Japan, 2Department ofColorectal and Hernia Surgery, The Fourth Affiliated Hospital of China Medical
University, 3Department of Infectious Disease, Shengjing Hospital of China Medical
University
1

1P-099Apolipoprotein C3-rich LDL induces endothelial dysfunction andvascular cells senescence in vivo
Ming-Yi Shen1,2,3), Li-Zhen Chen3), Ping-Hsuan Tsai4), Fang-Yu Chen1,2,3)

Department of Pharmacology, School of Medicine, China Medical University, Taiwan,
Department of Medicine Research, China Medical University Hospital, Taiwan,
Graduate Institute of Biomedical Science, China Medical University, Taiwan,
4
Department of Biological Science and Technology, China Medical University, Taiwan
12
3

1P-100

The Role of KLF1 in Mediating Immune Response
Chun Ju Yang1,2), Yu Chiau Shyu2,3,4,5)

1
Institute of Biopharmaceutical Sciences, University of Yang-Ming, Taiwan, 2Community
Medicine Research Center, Chang Gung Memorial Hospital, Taiwan, 3Institute of
Molecular Biology, Academia Sinica, Taiwan, 4Department of Nursing, Research Center
for Food and Cosmetic Safety, College of Human Ecology, Chang Gung University of
Science and Technology, Taiwan, 5Department of Nutrition and Health Sciences,
Research Center for Chinese Herbal Medicine, College of Human Ecology, Chang Gung
University of Science and Technology, Taiwan

1P-101

YAP promotes angiogenesis via STAT3 in endothelial cells
Jinlong He, Ding Ai, Yi Zhu

Tianjin Medical University, China

1P-102

Inhibition of PRC2 Protects against Restenosis via Suppressing Trimethylation of H3K27 in SMCs
Jing Liang

Department of Physiology, Tianjin Medical University, China
Circulation & Respiration: Vascular Physiology (1)1P-103

Gaseous components of cigarette smoke upregulate prostaglandin
E2 receptor EP4 in aortic aneurysm
Taro Hiromi1,2), Utako Yokoyama1), Al Mamun1), Tsunehito Higashi3),
Takahiro Horinouchi3), Souichi Miwa4), Ichiro Takeuchi2),
Yoshihiro Ishikawa1)

1P-104

Central command increases oxygenation of the non-contracting arm
muscles during fine hand movement
Ryota Asahara, Kanji Matsukawa, Kei Ishii, Izumi Okamoto, Yuki Sunami,
Hironobu Hamada, Tsuyoshi Kataoka, Wakana Oshita, Tae Watanabe
Department of Integrative Physiology, Hiroshima University, Japan

1P-105

Cold stimulation for the tympanic membrane decreases heart rate
Kunihiko Tanaka1), Akihiro Sugiura2)

Graduate School of Health and Medicine, Gifu University of Medical Science, Japan,
Department of Radiological Technology, Gifu University of Medical Science12

1P-106mGluR2/3 Agonist Suppresses Hypertension Development in SHR
Julia Chu-Ning Hsu, Shin-ichi Sekizawa, Masayoshi Kuwahara

Department of Veterinary Medical Sciences, Graduate School of Agricultural and Life
Sciences, The University of Tokyo

1P-107

Standard-dose gentamicin does not increase a risk of patent ductus
Toru Akaike, Ayana Kishibuchi, Susumu Minamisawa
Department of Cell Physiology, The Jikei University, Japan

1P-108

Role of TRPV4 on the spontaneous electrical properties of guinea pig
mesenteric lymphatic vessel
Hiromichi Takano, Hikaru Hashitani

Department of Cell Physiology, Nagoya City University, Japan

1P-109Physiological evidence that mesenteric lymph has been called as
white blood
Tomomi Watanabe-Asaka1,2), Daisuke Maejima2), Moyuru Hayashi1,2),
Yoshiko Kawai1,2), Toshio Ohhashi2)

Department of Physiology, Faculty of Medicine, Tohoku Medical and Pharmaceutical
University, Japan, 2Department of Innovation of Medical and Health Sciences Research,
Shinshu University School of Medicine, Japan
1

Endocrine, Reproduction & Development (1)1P-110

Mutual interaction of orexin-A and glucagon-like peptide-1 on reflex
swallowing in anesthetized rats
Motoi Kobashi1), Yuichi Shimatani2), Masako Fujita1), Yoshihiro Mitoh1),
Ryuji Matsuo1)

Department of Oral Physiology, Okayama University Graduate School of Medicine,
Dentistry and Pharmaceutical Sciences, Japan, 2Department of Medical Engineering,
Faculty of Engineering, Tokyo City University, Japan1

1P-111Age-dependent attenuation of hypothalamic sensitivity to thermo­
genic melanocortin signals
Manami Oya, Kazuhiro Nakamura

Circulation & Respiration: Vascular Physiology (1)/Endocrine, Reproduction & Development (1)

DAY 2

1
Cardiovascular Research Institute, Yokohama City University, Japan, 2Department ofEmergency Medicine, Yokohama City University, Japan, 3Department of Cellular
Pharmacology, Hokkaido University Graduate School of Medicine, Japan, 4Toyooka
Hospital, JapanDepartment of Integrative Physiology, Nagoya University, Graduate School of Medicine,Japan

1P-112Intake of caffeine in the morning exhibits anti-obesity effect on mice
fed with high-fat dietAtsushi Haraguchi, Tomohiro Yamazaki, Konomi Tamura, Shuhei Sato,
Shigenobu Shibata

Laboratory of Physiology and Pharmacology, School of Advanced Science andEngineering, Waseda University, Japan

1P-113

Effect of suppression of oral sweet-sensing with gymnema sylvestre
on food motivation in humans
Naomi Sano Kashima1), Kanako Kimura2), Natsumi Nishitani2),
Masako Yamaoko Endo2), Yoshiyuki Fukuba2), Hideaki Kashima2)

1
Department of Health and Nutrition, Hiroshima Shudo University, Japan, 2Department
of Exercise Science and Physiology, School of Health Sciences, Prefectural University ofHiroshima, Japan

1P-114

Impact of Aerobic Exercises on Hunger, Satiety and Food Intake inType 2 Diabetes Mellitus (T2DM)
Dinithi Vidanage1), Sudarshani Wasalathanthri2),
Priyadarshika Hettiarachchi3)

Department of Nursing and Midwifery, General Sir John Kotelawala Defence University,
Sri Lanka, 2Department of Physiology, University of Colombo, Sri Lanka, 3Department of
Physiology, University of Sri Jayewardenepura, Sri Lanka
1

1P-115

Possible improvement of cognitive function by long-term dark
chocolate ingestion in young subjects
Eri Sumiyoshi1), Kentaro Matsuzaki1), Naotoshi Sugimoto3), Yoko Tanabe1),
Toshiko Hara1), Masanori Katakura4), Mayumi Miyamoto2), Seiji Mishima5),
Osamu Shido1)

1
Department of Environmental Physiology, Shimane University, Japan, 2Fundamental
Nursing, Shimane University, Japan, 3Department of Physiology, Kanazawa University,
Japan, 4Department of Pharmaceutical Sciences, Josai University, Japan, 5Central
Clinical Laboratory, Shimane University Hospital, Japan

1P-116

Maternal low-protein-diet alters the glucose metabolism and its
intestinal mechanism of offspring
Nan Wang1), Ke Chen1), Bo Lv2), Hu Qiao3), Bo Hu3), Qun jian Yan1)

Department of Physiology and Pathophysiology, School of Basic Medical Sciences,
Xi'an Jiaotong University Health Science Center, China, 2School of Humanities, Xidian
University, China, 3Key Laboratory of Shaanxi Province for Craniofacial Precision
Medicine Research, Xi’an Jiaotong University College of Stomatology, China
1

1P-117

Importance of RANTES/CCR5 signaling in lipid oxidation andadaptive thermogenesis in micePei-Chi Chan1), Po-Shiuan Hsieh1,2)
12

1P-118Department of Physiology & Biophysics, National Defense Medical Center, Taiwan,
Institute of Preventive Medicine, National Defense Medical Center, Taiwan

Estradiol protects decrease in energy intake under psychosocial
stress in ovariectomized rats
Miho Nishimura, Sayaka Nishihara, Mariko Kawahara, Mizuho Kawakami,
Naoko Nakagi, Yuki Uchida, Akira Takamata, Keiko Morimoto

Dept. Environm. Health, Facult. Human Life & Environm, Sci., Nara Women's Univ., Japan

Endocrine, Reproduction & Development (1)1P-119

Involvement of phosphoinositide 3-kinase in leptin signaling in sweet
sensitive taste cells
Ryusuke Yoshida1), Robert F. Margolskee2), Yuzo Ninomiya2,3)

Department of Oral Physiology, Graduate School of Medicine, Dentistry andPharmaceutical Science, Okayama University, Japan, 2Monell Chemical Senses Center,
USA, 3Division of Sensory Physiology, Research and Development Center for Taste andOdor Sensing, Kyushu University, Japan1

CRF circuit involved in the regulation of food intake

Shuhei Horio1), Satoshi Yamagata2), Kenta Kobayashi3), Shigeki Kato4),
Kenji Sakimura5), Kazuto Kobayashi4), Yasuhiko Minokoshi1), Keiichi Itoi6)

Division of Endocrinology and Metabolism, National Institute for Physiological
Sciences, Japan, 2Graduate School of Medicine, Hirosaki University, Japan, 3Section ofViral Vector Development, National Institute for Physiological Sciences, Japan,
4
Department of Molecular Genetics, Fukushima Medical University, Japan, 5Brain
Research Institute, Niigata University, Japan, 6Graduate School of Information Sciences,
Tohoku University, Japan1

1P-121

Association between Birth weigh and some Metabolic Syndrome
Parameters among Medical Students
Tasabeeh Abd Allah Alnoor1), Lamis Abd Algadir Kaddam2),
Marwa Mohammed Ali 3), Faris Jamal Altekana4), Humeda Suiket Humeda5)

1
Department of Human Physiology, lecturer, University of Aneelain, Sudan, 2Departmentof Human Physiology, associate professor, University of Aneelain, Sudan, 3Departmentof Human Physiology,master candidate, University of Aneelain, Sudan, 4Department of
Human Physiology, medical student, University of Aneelain, Sudan, 5Department of
Human Physiology, assistant professor, International University of Africa, Sudan

1P-122

EID1 inhibits adipogenesis through reduction of GPDH expression
Tomohiko Sato1,2,3), Diana Vargas1,2), Saki Kawano2), Tomomi Maeyama2),
Amu Maruyama2), Kaoru Uchida2), Noriyuki Koibuchi1),
Noriaki Shimokawa1,2)

Department of Integrative Physiology, Gunma University Graduate School of Medicine,Japan, 2Department of Nutrition, Takasaki University of Health and Welfare, Japan,
Department of Physical Therapy, Ota College of Medical Technology, Japan

1

3

1P-123Macrophage Raptor deficiency-induced
exacerbates non-alcoholic steatohepatitis

lysosome

dysfunction

Chunjiong Wang, Wenli Liu, Chenji Ye, Yi Zhu, Ding Ai
Department of Physiology and Pathophysiology, Tianjin Medical University, China

1P-124

Capsaicinoid Nonivamide ameliorates hepatic injury on non-alcoholic
fatty liver disease in rat model
Naruemon Wikan1), Jiraporn Tocharus2), Sivanan Sivasinprasasn1),
Aphisek Kongkaew3), Waraluck Chaichompoo4), Apichart Suksamrarn4),
Chainarong Tocharus1)

Department of Anatomy, Faculty of Medicine, Chiang Mai University, Thailand,
Department of Physiology, Faculty of Medicine, Chiang Mai University, Thailand,3
Research Administration Section, Faculty of Medicine, Chiang Mai University, Thailand,
4
Department of Chemistry and Center of Excellence for Innovation in Chemistry,
Faculty of Science, Ramkhamhaeng University, Thailand
12

1P-125

Regulation of mitochondrial respiration, energy metabolism, andobesity by neuronal Ca2+-sensor-1
Tomoe Y Nakamura-Nishitani1), Shu Nakao2), Shigeo Wakabayashi3)

Dept. of Mol. Physiol., Natl. Cereb & Cardiovasc. Ctr., Japan, 2Stem Cell Regen. Med. Lab.,

1

Endocrine, Reproduction & Development (1)DAY 2

1P-120Col. Life Sci., Ritsumeikan Univ., Japan, 3Dept. Pharm., Osaka Med. Col., Japan

1P-126

Pioglitazone ameliorates senescence related markers in visceraladipose tissue of obese mice
Masaki Kimura, Risako Ishii, Natsumi Hirano, Ryoei Uchida, Shoji Yamada,
Yoshimasa Saito, Hidetsugu Saito
Division of Pharmacotherapeutics, Faculty of Pharmacy, Keio University, Japan

1P-127

Remote ischemic preconditioning affects gluconeogenesisvia thebrain-liver route
Yoshihiko Kakinuma1), Atsushi Kurabayashi2)

Department of Bioregulatory Science, Nippon Medical School Graduate School of
Medicine, Japan, 2Department or Pathology, Kochi Medical School1

1P-128Systemic glucose oxidation is enhanced in acquired liver and muscle
insulin receptor knockout mice
Kei Takahashi1), Tetsuya Yamada2), Takashi Sugisawa1), Keiko Kawata3),
Yoichiro Asai1), Yuichiro Munakata1), Shinjiro Kodama1), Shojiro Sawada1),
Junta Imai1), Makoto Inada3), Hideki Katagiri1)

Department of Metabolism and Diabetes, Tohoku University Graduate School of
Medicine, Japan, 2Department of Molecular Endocrinology and Metabolism, Graduate
School of Medical and Dental Sciences, Tokyo Medical and Dental University,
3
Diagnostic Division, Otsuka Pharmaceutical Co., Ltd.
1

1P-129CCL5 Deficiency Protect against High-fat Diet-induced Insulin
Resistance
Chao-Yu Kuo, Li-Man Hung

Department and Graduate Institute of Biomedical Sciences, College of Medicine,
Chang Gung University, Taiwan

1P-130The effects of insulin signaling on mouse taste bud organoid

Shingo Takai1), Peihua Jiang2), Robert F Margolskee2), Yuzo Ninomiya2,3),
Noriatsu Shigemura1,3)Section of Oral Neuroscience, Faculty of Dental Science, Kyushu University, Japan,
Monell Chemical Senses Center, 3Division of Sensory Physiology, Research andDevelopment Center for Taste and Odor Sensing, Kyushu University, Japan

1
2

1P-131Anti-hyperglycemic Effect Gynura Procumbens (Lour.) Merr. in In
vivo and In vitro Studies
Cho Lwin Aung1), Fumitaka Kawakami2), Motoki Imai2), Thet Thet Lwin3),
Ohnmar .4), Khin Phyu Phyu5), Mya Mya Thwin1), Hiroko Maruyama6)

1
Department of Physiology, University of Medicine 2, Myanmar, 2Department ofBiochemistry, Graduate School of Medical Sciences, Kitasato University, Japan,
3
Department of Radiology, Graduate School of Medical Sciences, Kitasato University,
Japan, 4Department of Physiology, University of Medicine, Myanmar, 5Department ofMedical Research (DMR), Myanmar, 6Department of Cytopathology, Graduate School of
Medical Sciences, Kitasato University, Japan

1P-132Whole organism chemical screening identifies modulators ofpancreatic β cell function
Hiroki Matsuda1,2), Sri Teja Mullapudi2), Carol Yang2), Hideki Masaki3),
Daniel Hesselson4), Didier Stainier2)

College of Life Sciences, Ritsumeikan University, Japan, 2Max Planck Institute for Heartand Lung Research, 3The Institute of Medical Science, University of Tokyo, 4Garvan
Institute of Medical Research
1

1P-133

Colonic smooth muscle injury ameliorates via SIRT1 activator in
STZ-Induced Diabetic Micee
Endocrine, Reproduction & Development (1)Hongli Lu1,2), Xu Huang1), Jie Chen2), Wenxie Xu1)
Department of Anatomy and Physiology, Shanghai Jiaotong University, School of
Medicine, China, 2Department of Pediatric Surgery, Xin Hua Hospital, Affiliated to
Shanghai Jiao Tong University School of Medicine, China
1

1P-134

Evaluation of anti-hyperglycemic efficacy of Lactobacillus paracasei
HII01 in type 2 diabetic rat
Department of Physiology, Faculty of Medicine, Chiang Mai University, Thailand,
Innovation Center for Holistic Health, Nutraceuticals and Cosmeceuticals, Faculty of
Pharmacy, Chiang Mai University, Thailand

12

1P-135White-skinned sweet potato stimulates insulin secretion frompancreatic β cells
Takuma Nagata, Takumi Shimada, Tetsuya Okuyama, Mikio Nishizawa,Eri Mukai
Graduate School of Life Sciences, Ritsumeikan University, Japan

1P-136

Correlation between hie-sho score and progesterone, fat intake inthe pre- and post-menopausal women
Yuki Uchida, Kyoko Ueshima, Koko Kano, Mayuko Minami, Yuri Mizukami,
Keiko Morimoto

Department of Health Sciences, Faculty of Human Life and Environment, Nara Women's
University, Japan

1P-137

Action mechanisms of sex steroids during puberty on sexual
differentiation of the brain in mice
Masahiro Morishita, Shinji Tsukahara

Division of Life Science, Graduate School of Science and Engineering, Saitama
University, Japan

1P-138

Role of Sphingosine-1-phosphate on the proliferative effect ofEstrogen in Human Osteoblast cells
Duangrat Tatikanlayaporn1), Pawinee Piyachaturawat2), Michelle R Witt3),
Irina C Tourkova4), Harry C Blair4)

Division of Cell Biology, Faculty of Medicine, Thammasat University, Thailand,
Department of Physiology, Faculty of Sciences, Mahidol University, Thailand,
3
Departments of Pathology and of Microbiology, Immunology & Cell Biology, West
Virginia University School of Medicine, 4Department of Pathology, University ofPittsburgh
12

1P-139Neonatal motor coordination is impaired by moderate perinatal
hypothyroidism in mice
Michifumi Kokubo1), Izuki Amano1), Wataru Miyazaki1), Yusuke Takatsuru2),
Asahi Haijima1), Shogo Haraguchi3), Noriyuki Koibuchi1)

Department of Integrative Physiololy, Gunma University Graduate School of Medicine,Japan, 2Department of Medicine, Johmoh Hospital, Japan, 3Department of Biochemistry,
Showa University School of Medicine, Japan1

1P-140Mifepristone upregulates vimentin expression in human hepatic
stellate cells
Takeshi Hashimoto, Katsuya Hirano

Department of Cardiovascular Physiology, Faculty of Medicine, Kagawa University,Japan

1P-141

CDK5 regulates estrogen receptor and breast cancer cell growth
Endocrine, Reproduction & Development (1)DAY 2

Parichart Toejing1), Nuntawat Khat-Udomkiri2), Sasithorn Sirilun2),
Chaiyavat Chaiyasut2), Narissara Lailerd1)

Chia Wei Huang1), Yueh-Tsung Lee2), Wei-Huan Huang3), Mei-Chih Chen3,4),
Ho Lin1)
1
Department of Life Sciences, National Chung Hsing University, Taiwan, 2Division ofGeneral Surgery, Chang Bing Show Chwan Memorial Hospital, Taiwan, 3Medical
Research Center for Exosomes and Mitochondria Related Diseases, China Medical
University Hospital, Taiwan, 4Department of Nursing, Asia University, Taiwan

1P-142

Effect of Blood Donation on Insulin Resistance and Lipid Peroxidation
Product
Thet Khaing Lei Maung, Zin Maung Tun

Department of Physiology, University of Medicine Mandalay, Myanmar

1P-143Ghrelin modulates duration or number of wakefulness, NREM andREM sleep event
Ryosuke Okumura, Toshiki Tajima, Takuya Mukai, Taiga Yamashita,
Taichi Kakizawa, Juhyon Kim, Kazuki Nakajima

Division of Bio-Information Engineering, Faculty of Engineering, University of Toyama,Japan

1P-144

Estrogen deficiency leads to decreased water channel aquaporin 4
expression in skeletal muscle
Yung-Li Hung1), Keigo Ota2), Minenori Ishido3), Shuichi Machida2)

Institute of Health and Sports Science & Medicine, Juntendo University, Japan,
Graduate School of Health and Sports Science, Juntendo University, 3Section for
Health‑related Physical Education, Division of Human Sciences, Faculty of Engineering,Osaka Institute of Technology
12

1P-146The expression of the arginine vasopressin gene in the rat
hypothalamus of EAE model
Kentaro Tanaka, Haruki Nishimura, Kazuaki Nishimura, Satomi Sonoda,
Hiromichi Ueno, Takanori Matsuura, Reiko Saito, Mitsuhiro Yoshimura,
Takashi Maruyama, Koichi Kusuhara, Yoichi Ueta

Department of Physiology, School of Medicine, University of Occupational andEnvironmental Health, Japan

1P-147

Effect of persistent nicotine exposure on cell differentiation in rat
pituitary gland
Masashi Higuchi, Takahiro Yamaguchi, Ayaka Hibara, Yoshiaki Yamano

Laboratory of Veterinary Biochemistry, Joint Department of Veterinary Medicine,
Faculty of Agriculture, Tottori University, Japan

1P-148

Identification and functional analysis of inhibin βE (INHBE) as ahepatokine
Akihiro Kikuchi1,2), Hirofumi Misu2), Hirobumi Igawa 2),
Yasuhiko Minokoshi 1), Toshinari Takamura 2)

Division of Endocrinology and Metabolism, National Institute for Physiological
Sciences, Japan, 2Department of Endocrinology and Metabolism, Kanazawa University
Graduate School of Medical Sciences, Japan1

1P-149Serum leptin adiponectin and their effects on obesity among
adolescents in Colombo district Sri Lanka
Thilini Abeyratne1), Sharaine Fernando2), Rasika Perera3)

Department of Allied Health Sciences, Univesity of Sri Jayewardanepura, Sri Lanka,
Department of Physiology, Univesity of Sri Jayewardanepura, Sri Lanka, 3Departmentof Biochemistry, Univesity of Sri Jayewardanepura, Sri Lanka
12

1P-151

Targeting FGF/FGFR axis ameliorates endometriosis progression
Endocrine, Reproduction & Development (1)Pei-Chin Chuang3), Wen-Hong Su1), Shaw-Jenq Tsai3), Meng-Hsing Wu2)
Department of Medical Research, Chang Gung Memorial Hospital, Taiwan,
Department of Obstetrics & Gynecology, College of Medicine, National Cheng Kung
University, Taiwan, 3Department of Physiology, College of Medicine, National Cheng
Kung University, Taiwan
12

1P-152

Subepithelial synchronous interstitial cells drive spontaneouscontractions in the seminal vesicle
1
Dept. Physiol., Kurume Univ. Sch. Med., Japan, 2Dept. Cell Physiol., Grad. Sch. Med. Sci.,
Nagoya City Univ., Japan, 3Dept. Urol., Kurume Univ. Sch. Med., Japan, 4Advanced
Imaging Research Center, Kurume Univ. Sch. Med., Japan, 5Dept. Anat., Kurume Univ.
Sch. Med., Japan

1P-153Chronological change in concepts and symptoms of premenstrual
syndrome of female university students
Ayaka Matsuo, Shunta Maruo, Takayoshi Hosono

Department of Biomedical Engineering, Osaka Electro-Communication University,Japan

1P-154

Expression and function of GLUT1-4 in mouse endometrium during
the preimplantation periodLong Yun, Li Nie, Yuan Dong Zhi, Liu Min, Zhao Dan, Wang Yi Cheng,
Zhang Xue Qing, Lei Yi, Wang Mei Jiao, Zhang Jin Hu, Yue Li Min
Department of Physiology, University of SiChuan, China

1P-155The dynamic expression of PTEN in the development of mouse spirallimbusYouyi Dong, Kazuyo Kamitori

Department of Molecular Physiology, Faculty of Medicine, Kagawa University, Japan

1P-156The effect of post-natal PFOS exposure on cerebellar development
and motor coordination
Abdallah Mshaty , Asahi Haijima, Wataru Miyazaki, Noriyuki Koibuchi
Integrative Physiology Department, Gunma University, Japan

1P-157The effects of thyroid hormone on development of hippocampal
neurons in vitro
Hiroyuki Yajima1), Izuki Amano1), Wataru Miyazaki1), Yusuke Takatsuru2),
Noriyuki Koibuchi1)

Department of Integrative Physiology, Gunma University, Japan, 2Department ofMedicine, Johmoh Hospital, Japan1

1P-158Perceptions towards health and care giving among elderly withloneliness, living in aged-care homes
Hapuarachchige Sewvandi Maliga Sampath Kumari Wijesiri1),
Kerstin Samarasinghe2)

Department of Nursing and Midwifery, Faculty of Allied Health Sciences, General Sir
John Kotelawala Defence University, Sri Lanka, 2Department of Health Sciences,
Kristianstad University, Sweden

1

1P-159Krüppel-like factor 5 regulates proliferation of neural precursor cells
in the developing brain
Takahiro Fuchigami1), Yoshitaka Hayashi1), Anri Kuroda1), Takuya Azami2),
Masatsugu Ema2), Seiji Hitoshi1)

Department of Integrative Physiology, Shiga University of Medical Science, Japan,

1

Endocrine, Reproduction & Development (1)DAY 2

Mitsue Takeya1), Hikaru Hashitani2), Tokumasa Hayashi3), Ryuhei Higashi4),
Kei-Ichiro Nakamura5), Makoto Takano1)

2

1P-160Research Center for Animal Life Science, Shiga University of Medical Science, Japan

Rescue of craniofacial defects with therapeutic hedgehog target
chemical in ECO syndrome mouse model
Jeong-Oh Shin1), Jieun Song2), Hyuk Wan Ko2), Jinwoong Bok1)

1
Department of Anatomy, Yonsei University College of Medicine, Korea, 2Department ofBiochemistry, College of Life Science and Biotechnology, Yonsei University

Neuroscience: Synapse & neural cellular communication (1)1P-161

Nicotine layer-specifically modulates synaptic plasticity in the mouseinsular cortex
Hiroki Toyoda, Hajime Sato, Dong-Xu Yin, Takafumi Kato

Department of Oral Physiology, Osaka University Graduate School of Dentistry, Japan

1P-162Large volume electron microscopy and neural microcircuitanalysis
Yoshiyuki Kubota1,2), Jaerin Sohn1,3), Yasuo Kawaguchi1,2)

1
Div Cerebral Circuitry, National Institute for Physiological Sciences, Japan, 2Dept
Physiological Sciences, The Graduate University for Advanced Studies (SOKENDAI),
3
Research Fellow of Japan Society for the Promotion of Science (JSPS), Japan

1P-163

Stimulated single fiber electromyography in orbicularis oculi muscle
in profenofos poisoned patients
Chanika Alahakoon1), Tharaka Lagath Dassanayake1),
Indika Bandara Gawarammana2), Vajira Senaka Weerasinghe1)

Department of Physiology, University of Peradeniya, Sri Lanka, 2Department ofMedicine, University of Peradeniya, Sri Lanka

1

1P-164

Conduction filtering of synaptic currents via dendrites by SK channels
in cerebellar Purkinje cells
Gen Ohtsuki

Hakubi Center / Department of Biophysics, Kyoto University, Japan

1P-165

Bidirectional dopamine-dependent synaptic plasticity at IPSC of SNr
GABA neurons in young rat slice
Takefumi Miyazaki

Department of Physiology, Tokyo Medical University, Japan

1P-166

Miniature inhibitory postsynaptic current in cerebellar Purkinje cellsof old dystrophic mdx mice
Chek Ying Tan, Sindy Lyn Ling Kueh, Stewart Ian Head,John William Morley
School of Medicine, Western Sydney University, Australia

1P-167

Src kinase regulates the presynaptic transmitter release in avian
cochler nucleus
Takayuki Furuta, Rei Yamada, Hiroshi Kuba

Department of Cell Physiology, University of Nagoya, Japan

1P-168The mGluR1 contributes strengthening and maintenance ofdeveloping lemniscal synapses
Madoka Narushima1,2), Yuki Yagasaki1), Yuichi Takeuchi1), Mariko Miyata1)1Dept Physiol, Div Neurophysiol, Sch Med, Tokyo Women's Medical Uni, Japan, 2Div
Homeostatic Development, NIPS, Japan

1P-169Inhibition expands dynamic range of inputs in low-tuning frequency
neurons in avian cochlear nucleus

Endocrine, Reproduction & Development (1)/Neuroscience: Synapse & neural cellular communication (1)Mohammed Al-Yaari, Rei Yamada, Hiroshi Kuba
Department of Cell Physiology, Japan

1P-1705-HT-induced inhibition of excitatory transmission onto basal
forebrain cholinergic neurons
Takuma Nishijo, Toshihiko Momiyama

Department of Pharmacology, Jikei University School of Medicine, Japan

Electrophysiological comparison-negative Punkinje cells

betweenzebrin-positive

andViet Tuan Nguyen-Minh, Anh Khoa Tran, Yuanjun Luo, Izumi Sugihara
Department of Systems Neurophysiology, Tokyo Medical and Dental University, Japan

1P-172

Actin-associated tropomyosins in the dendritic spine play a role insynaptic function
Chanchanok Chaichim1), Holly Stefen1), Merryn Brettle1),
Peter W Gunning1), Edna C Hardeman1), Thomas Fath1,2), John M Power1)

School of Medical Sciences, UNSW Sydney, Australia, 2Department of Biomedical
Sciences, Macquarie University, Australia

1

1P-173New method to prevent the visually-evoked somatic depolarization
for spine imaging
Satoru Kondo1,2), Kenichi Ohki1,2)

1
IRCN, The University of Tokyo Institutes for Advanced Study , The University of Tokyo,
Japan, 2Department of Physiology, School of Medicine, The University of Tokyo

1P-174

Fndc3b promotes climbing fiber synapse elimination partly byinhibiting STAT3 in the cerebellum
Kushibe Kyoko1), Celine Mercier1), Takaki Watanabe1), Taisuke Miyazaki2),
Miwako Yamasaki2), Masahiko Watanabe2), Naofumi Uesaka1),
Masanobu Kano1)1Dept of Neurophysiol, University of Tokyo, Japan, 2Dept of Anat, Hokkaido Univ Grad
Sch of Med, Japan

1P-175Distinct kinetics of synaptic vesicle replenishment mediated bysynaptotagmin 1, 2 and 7
Shota Tanifuji1), Ken Kojima2)

1
Department of Physiology, Tokyo Medical University, Japan, 2Pre-clinical ResearchCenter, Tokyo Medical University, Tokyo, Japan

1P-176

Synaptic clustering regulates the auditory coincidence detection in
low tuning frequency neurons
Rei Yamada, Hiroshi Kuba

Department of Cell Physiology, Graduate School of Medicine, Nagoya University, Japan

Neuroscience: Neural cell signalling
1P-177

Function of type 1 metabotropic glutamate receptors in the neonatal
rat hippocampal marginal zone
Megumi Taketo

Department of Cellular and Functional Biology Institute of Biomedical Science, Facultyof Medicine, Kansai Medical University, Japan

1P-178

Sodium channel-independent components of axonal afterdepolarization in hippocampal mossy fibers
Shunsuke Ohura, Haruyuki Kamiya

Neuroscience: Synapse & neural cellular communication (1)/Neuroscience: Neural cell signalling

DAY 2

1P-171Dept Neurobiol, Grad Sch Med, Hokkaido Univ, Japan

1P-179Different taste sensitivity to salt and amiloride relates localization in
the rat rNST neurons
Tatsuko Yokota, Katsunari Hiraba

Department of Physiology, School of Dentistry, Aichi-Gakuin University, Japan

1P-180Olfactory marker protein controls cAMP-throughput capacity via
cAMP-gated channels in normosmia
Noriyuki Nakashima1), Kie Nakashima2), Akiko Taura3), Akiko Nakashima4),
Harunori Ohmori5), Makoto Takano1)

1
Department of Physiology, Kurume University School of Medicine, Japan, 2Laboratoryof Developmental Neurobiology, Graduate School of Biostudies, Kyoto University,
Japan, 3Department of Medical Engineering, Faculty of Health Science, Aino University,
Japan, 4Post Graduate Training Program, The University of Tokyo Hospital, Japan,
5
Department of Physiology, School of Medicine, Kanazawa Medical University, Japan

1P-181

Melatonin does not protect the brain against cardiac ischemia/
reperfusion injury
Nattayaporn Apaijai1,2), Kodchanan Singhanat1,2,3), Thidarat Jaiwongkam1,2),
Siriporn C Chattipakorn1,2,4), Nipon Chattipakorn1,2,3)

Cardiac Electrophysiology Research and Training Center, Faculty of Medicine, Chiang
Mai University, Thailand, 2Center of Excellence in Cardiac Electrophysiology Research,
Chiang Mai University, Thailand, 3Cardiac Electrophysiology Unit, Department of
Physiology, Faculty of Medicine, Chiang Mai University, Thailand, 4Department of Oral
Biology and Diagnostic Sciences, Faculty of Dentistry, Chiang Mai University, Thailand
1

1P-182Developmental regulation of Ca channel expression in avian cochlear
nucleusKensuke Muto, Rei Yamada, Hiroshi Kuba

Department of Cell Physiology, Graduate School of Medicine, Nagoya University, Japan

1P-183Mechanisms underlying WNK3 kinase mediated regulation ofneuronal excitability in prefrontal cortex
Adya Saran Sinha1), Tianying Wang1), Yasushi Hosoi1), Eisei Sohara2),
Tenpei Akita1), Shinichi Uchida2), Atsuo Fukuda1)

Department of Neurophysiology, Hamamatsu University School of Medicine, Japan,
Department of Nephrology, Graduate School of Medical and Dental Sciences, Tokyo
Medical and Dental University, Japan

1
2

1P-184Ca2+ signaling and ion channel activation in embryonic neurons in the
medial ganglionic eminence
Tenpei Akita, Atsuo Fukuda

Department of Neurophysiology, Hamamatsu University School of Medicine, Japan

1P-185GABA in the suprachiasmatic nucleus refines circadian behavioral
rhythms
Daisuke Ono1), Ken-Ichi Honma2), Yuchio Yanagawa3), Akihiro Yamanaka1),
Sato Honma2)

1
Research Institute of Environmental Medicine, Nagoya University, Japan, 2Researchand Education Center for Brain Science, Hokkaido University Graduate School of
Medicine, Japan, 3Department of Genetic and Behavioral Neuroscience, Gunma
University Graduate School of Medicine, Japan

1P-186

Calpain inhibition modulates NMDAR responsiveness to calcium
increases in midbrain dopamine neurons
Shinhye Kim, Sun Hee Jeon, Hyung Seo Park, Se Hoon Kim
Neuroscience: Neural cell signallingDepartment of Physiology, College of Medicine, Konyang University, Korea

1P-187

P2X7 receptor-pannexin-1 channel interaction in rat trigeminal
ganglion neuron
Hiroyuki Inoue1), Hidetaka Kuroda2), Noboru Ishikawa3), Sadao Ohyama4),
Asuka Higashikawa4), Maki Himura4), Hitoshi Yamamoto3),
Yoshiyuki Shibukawa4), Tatsuya Ichinohe1)

Neuroscience: Brain circuits
1P-188Oxygen affects simple circuit for cold acclimation via KQT potassiumchannel and HADH in C. elegans
Atsushi Kuhara1,3), Mayu Fujita1), Misaki Okahata1), Yohei Minakuchi2),
Atsushi Toyoda2), Akane Ohta1)

1Inst. for Integrative Neurobio., Konan University, Japan, 2National Institute of Genetis,
Japan, 3PRIME, AMED

1P-189Corticocortical mechanisms underlying
consolidation during NREM sleep

perceptual

memoryDaichi Hirai1,2), Daisuke Miyamoto1), Yasuhiro Oisi1), Maya Odagawa1),
Chie Matsubara1), Kanako Ueno1), Kenta Kobayashi3),
Akiko Hayashi-Takagi4), Masanori Murayama1)
Lab for Haptic Perception and Cognitive Physiology, RIKEN Center for Brain Science,
Japan, 2Research Fellow, Japan Society for the Promotion of Science (JSPS), Japan, 3Lab
Viral Vector Development, Natl Inst Physiol Sci, Japan, 4Laboratory of Medical
Neuroscience, Institute for Molecular and Cellular Regulation, Gunma University, Japan1

1P-190Physiological and anatomical organization of cortico-striatal inputs inthe basal ganglia
Hiromi Sano1,2), Kenta Kobayashi2,3), Shigeki Kato4), Satomi Chiken1,2),
Kazuto Kobayashi4), Atsushi Nambu1,2)

Division of System Neurophysiology, NIPS, Japan, 2Department of Physiological
Sciences, SOKENDAI, Japan, 3Section of Viral Vector Development, NIPS, Japan,
4
Department of Molecular Genetics, Fukushima Med. Univ., Japan1

1P-191

Effects of acute kidney dysfunction on arginine vasopressin intransgenic rats
Hiromichi Ueno, Kenya Sanada, Kentaro Tanaka, Haruki Nishimura,Kazuaki Nishimura, Satomi Sonoda, Yoshihiro Yoshimura,
Takashi Maruyama, Yutaka Otsuji, Yoichi Ueta

Department of Physiology, University of Occupational and Environmental Health,Japan

1P-192How does the cerebellum control thalamocortical activity?

Satomi Chiken1,2), Hiromi Sano1,2), Kenta Kobayashi2,3), Atsushi Nambu1,2)

Division of System Neurophysiology, National Institute for Physiological Sciences,
Japan, 2Department of Physiological Sciences, SOKENDAI, Japan, 3Section of Viral Vector
Development, National Institute for Physiological Sciences, Japan1

1P-193The perioral sensory signaling pathway for complex spike generationin cerebellar Purkinje cells
Reika Kubo1), Atsu Aiba2), Kouichi Hashimoto1)

Neuroscience: Neural cell signalling/Neuroscience: Brain circuits

DAY 2

1
Department of Dental Anesthesiology, Tokyo Dental College, Japan, 2Department
Critical Care Medicine and Dentistry, Kanagawa Dental University Graduate School of
Dentistry, Japan, 3Department of Histology and Developmental Biology, Tokyo Dental
College, 4Department of Physiology, Tokyo Dental College, JapanDepartment of Neurophysiology, Graduate School of Biomedical and Health Sciences,
Hiroshima University, Japan, 2Laboratory of Animal Resources, Center for Disease
Biology and Integrative Medicine, Graduate School of Medicine, The University ofTokyo, Japan1

1P-194

Examination into effects of stimulation of the lateral habenula on
cardiovascular responses in rats
Tri Huu Doan1,2,4), Yuma Sato1,3), Masayuki Matsumoto1),
Tadachika Koganezawa1)

Department of Physiology, Faculty of Medicine, University of Tsukuba, Tsukuba, Japan,
Doctoral Program in Biomedical Sciences, Graduate School of Comprehensive Human
Sciences, University of Tsukuba, Japan, 3School of Medical Sciences, University ofTsukuba, Japan, 4Center for Advanced Training in Clinical Simulation, University of
Medicine and Pharmacy at Ho Chi Minh City, Vietnam
12

1P-195NMDA receptor-mediated activation of excitatory networks in rat
interstitial nucleus of Cajal
Yasuhiko Saito

Department of Neurophysiology, Nara Medical University, Japan

1P-196

Topographic representation of saccade vector in frontal eye field ofcommon marmoset
Chih-Yang Chen, Denis Matrov, Kuan-Ting Ho, Tadashi Isa

Division of Physiology and Neurobiology, Department of Neuroscience, Graduate
School of Medicine, Kyoto University, Japan

1P-197

Measurement of multiple cerebellar mossy fiber activities by calcium
imaging in mouse
Satoshi Manita1), Koji Ikezoe1), Masaaki Sato2,3), Masamichi Ohkura2,3),
Junichi Nakai2,3), Yasunori Hayashi4), Kazuo Kitamura1)

Department of Neurophysiology, Faculty of Medicine, University of Yamanashi, Japan,
Graduate School of Science and Engineering, Saitama University, Japan , 3Brain and
Body System Science Institute, Saitama University, Japan, 4Department of Pharmacology,
Graduate School of Medicine, Kyoto University, Japan
1
2

1P-198

Activity-dependent formation and restoration of callosal axon
projections in developing neocortex
Yoshiaki Tagawa1,2), Yuta Tezuka2), Kenta Hagihara3), Kenichi Ohki4),
Tomoo Hirano2)

Department of Physiology, Graduate School of Medical and Dental Sciences,
Kagoshima University, Japan, 2Department of Biophysics, Graduate School of Science,
Kyoto University, Japan, 3Friedrich Miescher Institute, Neurobiology, Switzerland,
4
Department of Physiology, Graduate School of Medicine, University of Tokyo, Japan1

1P-199Neural ensemble dynamics during P-waves in mice
Tomomi Tsunematsu1,2,3,4), Arno Onken5), Shuzo Sakata1)

Strathclyde Institute of Pharmacy and Biomedical Sciences, University of Strathclyde,
Japan, 2Frontier Research Institute for Interdisciplinary Sciences, Tohoku University,
Super-network Brain Physiology, Graduate School of Life Sciences, Tohoku University,
4
JST, PRESTO, 5School of Informatics, University of Edinburgh
13

1P-200The neural connections between the oculomotor neural integratorsand the vestibulo-cerebellum
Taketoshi Sugimura, Yasuhiko Saito

Department of Neurophysiology, Nara Medical University, Japan

1P-201

Serotonin regulated the fetal movement-like activity in the spinal cord
Reona Furukawa1), Chiaki Uchida1), Hirotaka Ooka1), Yoshiyuki Ohmura2),
Neuroscience: Brain circuits

Akiko Arata1)
1
Department of Physiology, Hyogo College of Medicine, Japan, 2Lab. for Intell. Sys. &Informatics, Dept. Mechano-Informatics, School of Information Science & Technology,
Univ. of Tokyo, Japan

1P-202Function of inhibitory neurons in the solitary nucleus in the control ofrespiration
Department of Neural and Muscular Physiology, Shimane University School of
Medicine, Japan, 2Department of Anatomy and Neuroscience, Shimane University
School of Medicine, 3Clinical Research Center, Murayama Medical Center, 4Cellular and
Systems Neurobiology Section, NINDS, NIH

1

1P-203

Information processing in brainstem bitter taste-relaying neurons
Makoto Sugita, Kuniyo Yamamoto

Department of Physiology and Oral Physiology, Graduate School of Biomedical &Health Sciences, Hiroshima University, Japan

1P-204

Inhibitory local connection of parvalbumin-expressing neurons in the
rat globus pallidus
Tetsuya Higashiyama1), Fuyuki Karube1), Yasuharu Hirai1),
Kenta Kobayashi2), Fumino Fujiyama1)

Department of Brain Science, Doshisha University, Japan, 2Section of Viral Vector
Development, Center for Genetic Analysis of Behavior, NIPS, Japan1

1P-205

Effects of hypovolemia and osmotic challenge on arginine vasopressin
synthesis in transgenic rats
Kenya Sanada1,2), Hiromichi Ueno1,2), Hiroki Beppu1), Kentaro Tanaka1),
Haruki Nishimura1), Kazuaki Nishimura1), Satomi Sonoda1),
Mitsuhiro Yoshimura1), Takashi Maruyama1), Yutaka Otsuji2, Yoichi Ueta1)

Department of Physiology, University of Occupational and Environmental Health,Japan, 2Department of Cardiovascular Medicine and Nephrology

1

1P-206

Sex difference of oxytocin and vasopressin dynamics in the
hypothalamus of rats
Kazuaki Nishimura1,2), Kenya Sanada1), Hiroki Beppu1), Haruki Nishimura1),
Kentaro Tanaka1), Satomi Sonoda1), Hiromichi Ueno1),
Mitsuhiro Yoshimura1), Takashi Maruyama1), Kiyoshi Yoshino2), Yoichi Ueta1)

Department of Physiology, School of Medicine, University of Occupational andEnvironmental Health, Japan, 2Department of Obstetrics and Gynecology, School of
Medicine, University of Occupational and Environmental Health, Japan1

1P-207

Projection-specific cortico-cortical transformations in the mouse
visual system
Fumitaka Osakada1,2,3)

Laboratory of Cellular Pharmacology, Graduate School of Pharmaceutical Sciences,
Nagoya University, Japan, 2Laboratory of Neural Information Processing, Institute forAdvanced Research, Nagoya University, Japan, 3PRESTO, Japan Science and Technology
Agency, Japan1

1P-208Presynaptic H3 heteroreceptor in nucleus accumbens mediates
anxiolytic effect of histamine
Jing-Ning Zhu1,2), Shi-Yu Peng1), Bin Li1), Qian-Xing Zhuang1), Shu-Tao Xie1),
Jian-Jun Wang1,2)

State Key Laboratory of Pharmaceutical Biotechnology and Department of Physiology,
School of Life Sciences, Nanjing University, China, 2Institute for Brain Sciences, Nanjing
University, China
1

Neuroscience: Brain circuits

DAY 2

Noriyuki Hama1), Shigefumi Yokota2), Masashi Fujitani1,2), Yasumasa Okada3),
Naohiro Koshiya4), Hidehiko Koizumi4)

1P-209

VTA neurons targeting cortical motor areas exhibit highly diffuse
collateral projections
Yoshinori Koshimizu1,3), Kenta Kobayashi2,3), Kaoru Isa1,3), Tadashi Isa1,3)

Department of Neurophysiology, Graduated School of Medicine, University of Kyoto,
Japan, 2Laboratory of Viral Vector Development, National Institute for Physiological
Sciences, Japan, 3CREST, JST, Japan1

1P-210Phasic increase of interleukin 1 in the dorsal raphe nucleus affects
inter-male aggressive behavior
Aki Takahashi1,2,3), Hossein Aleyasin2), Mihaela A Stavarache4),
Meghan E Flanigan2), Caroline Menard2), Madeline L Pfau2),
Georgia E Hodes2), Sonoko Ogawa1), Bruce S Mcewen3), Scott J Russo2)

1
Laboratory of Behavioral Neuroendocrinology, University of Tsukuba, Japan, 2Center
for Affective Neuroscience and Friedman Brain Institute, Icahn School of Medicine atMount Sinai, 3Laboratory of Neuroendocrinology, The Rockefeller University,
4
Department of Neurological Surgery, Weill Cornell Medical College

1P-211

Cerebellar integration of neocortical somatosensory signals
Misa Shimuta1), Izumi Sugihara2), Taro Ishikawa1)

1
Dept. Pharmacology, Jikei Univ. Sch. of Med., Japan, 2Dept. Systems Neurophysiol.,Tokyo
Med. Dent. Univ., Japan

1P-212

Phox2b-expressing neurons in the rat reticular formation dorsal to
the trigeminal motor nucleus
Shiro Nakamura1), Kouta Nagoya2), Keiko Ikeda3), Hiroshi Onimaru4),
Kiyoshi Kawakami5), Kiyomi Nakayama1), Ayako Mochizuki1),
Masanori Dantsuji1), Tomio Inoue1)

1
Department of Oral Physiology, Showa University School of Dentistry, Japan, 2Divisionof Dysphagia Rehabilitation, Department of Oral Biological Science, Faculty of Dentistry
Niigata University, 3Department of Physiology, School of Medicine, International
University of Health and Welfare, 4Department of Physiology, Showa University Schoolof Medicine, 5Division of Biology, Center for Molecular Medicine, Jichi Medical University

1P-213

Neural activity underlying mismatch negativity generation in macaquetemporal and frontal cortices
Yuki Suda1), Mariko Tada2), Takeshi Matsuo3), Keisuke Kawasaki4),
Takafumi Suzuki5), Isao Hasegawa4), Kenji Matsumoto1), Kiyoto Kasai2),
Takanori Uka 6)

1
Brain Science Institute, Tamagawa University, Tokyo, Japan, 2Department of
Neuropsychiatry, Graduate School of Medicine, University of Tokyo, 3Department of
Neurosurgery, Tokyo Metropolitan Neurological Hospital, Tokyo, 4Department of
Neurophysiology, Niigata University School of Medicine, 5Center for Information and
Neural Networks (CiNet), National Institute of Information and Communications
Technology, and Osaka University, 6Department of Integrative Physiology, Graduate
School of Medicine, University of Yamanashi

1P-214

CRH release regulation by GABAergic projection from arcuate
nucleus using chemogenetic model
Ruksana Yesmin, Miho Watanabe, Atsuo Fukuda

Department of Neurophysiology, Hamamatsu University School of Medicine, Japan

1P-215

Exploring the roles of calbindin-D28K in the medial preoptic nucleus
in sexual behavior of male rats
Sho Maejima1), Masahiro Morishita2), Kanna Ueno2), Arisa Kamada2),
Shinji Tsukahara1,2)

Area of Life-NanoBio, Division of Strategy Research, Graduate School of Science and1

Neuroscience: Brain circuits

Engineering, Saitama University, Japan, 2Area of Regulatory Biology, Division of Life
Science, Graduate School of Science and Engineering, Saitama University, Japan

1P-216

ASIC1a mediates striatal synapse remodeling and procedural motor
learning
Wei-Guang Li, Zhe Yu, Yan-Jiao Wu, Tian-Le Xu

Department of Anatomy and Physiology, Shanghai Jiao Tong University School of
Medicine, China

1P-218

Effects of ELF-EMF on learning and memory, anxiety-like behavior
and stress oxidative in male rats
Iraj Salehi1,2), Seyed Asaad Karimi1,2), Alireza Komaki1,2)

Neurophysiology Research Center, Hamadan University of Medical Sciences, Iran,
Department of Neuroscience, School of Advanced Technologies in Medicine,
Hamadan University of Medical Sciences, Iran1
2

1P-219Ventral hippocampus inactivation facilitates the attenuation of
olfactory neophobia in rats
Keisuke Shinohara, Yasunobu Yasoshima

Division of Behavioral Physiology, Department of Human Sciences, Osaka University,Japan

1P-220Effect of Castration on Electrophysiological Properties
Neurons in Adult Male Zebra Finches

of LMAN

Dongfeng Li, Li Wu

School of Life Science, South China Normal University, China

1P-221

MMP-9 activity is required for the NMDA induced endocytosis of
AMPA receptor
Shinnosuke Kohara1), Shinji Matsuda1,2)

Department of Engineering Science, University of Erectro-Communications, Japan,
Brain Science Inspired Life Support Research Center (BLSC), The University of ElectroCommunications

1
2

1P-222

Impairment of Long-term Plasticity in Purkinje Cell with Dominantnegative Thyroid Hormone Receptor
Ayane Ninomiya1), Nobutake Hosoi2), Michifumi Kokubo1), Izuki Amano1),
Asahi Haijima1), Wataru Miyazaki1), Hirokazu Hirai2), Noriyuki Koibuchi1)1Dept. Integrative Physiology, Grad. Sch. Med., Gunma Univ., Japan,
Neurophysiology and Neural Repair, Grad. Sch. Med., Gunma Univ., Japan

1P-2232

Dept.

Remote memory traces in the mouse hippocampus revealed by Arcbased functional labeling
Hiroyuki Okuno1,2), Anna Araki2), Keiichiro Minatohara1,2), Haruhiko Bito4),
Itaru Imayoshi2,3)

Dept. of Biochem. and Molec. Biol., Kagoshima University Graduate School of Medical
and Dental Sciences, Japan, 2Med. Innov. Ctr., Graduate School of Medicine, Kyoto
University, Japan, 3Graduate School of Biostudies, Kyoto University, Japan, 4Dept. of
Neurochem., Graduate School of Medicine, The University of Tokyo, Japan1

1P-224

Plasmalogens enhance spatial memory in mice by increasing thegene expression in hippocampus
Md Shamim Hossain1), Sanyu Sejimo1), Yutaka Oomura1), Takehiko Fujino2)

Department of Neuroinflammation and Brain Fatigue Science, Graduate School of
Medical Sciences, Kyushu University, Japan, 2Institute of Rheological Functions of Food

1

Neuroscience: Brain circuits/Neuroscience: Learning, memory & neuronal plasticity (1)DAY 2

Neuroscience: Learning, memory & neuronal plasticity (1)1P-225

Reaction time property of visual working memory to adjacent twolever task in standing rats
Masatoshi Takita1,2), Sei-etsu Fujiwara3), Yukio Ichitani4)

Human Informatics Research Institute, National Institute of Advanced Industrial
Science and Technology (AIST), Japan, 2Brain Science Inspired Life Support ResearchCenter, The University of Electro-Communications, Japan, 3Department of Physiology,
St Marianna University School of Medicine, Japan, 4Faculty of Human Sciences,
University of Tsukuba, Japan1

1P-226

Gut Dysbiosis Induced Brain Pathological Changes and Cognitive
Decline in HFD-Fed Rats
Napatsorn Saiyasit1,2), Dillon Prus1), Kanokphong Suparan1),
Sasiwan Kredphoo1,2), Thidarat Jaiwongkum1,2), Jirapas Sripetchwandee1,2),
Nipon Chattipakorn1,2), Siriporn C Chattipakorn1,3)

Neurophysiology Unit, Cardiac Electrophysiology Research and Training Center,
Faculty of Medicine, Chiang Mai University, Thailand , 2Department of Physiology,
Faculty of Medicine, Chiang Mai University, Thailand, 3Department of Oral Biology and
Diagnostic Sciences, Faculty of Dentistry, Chiang Mai University, Thailand
1

1P-227

PKD1 promotes functional synapse formation coordinated with
N-cadherin in hippocampus
Cen Cheng, Luo Li-Da

Neuroscience Research Institute, Peking University, China

1P-228

Dynamics of cell assemblies in hippocampus during memory
consolidation and recall
Shogo Takamiya, Shoko Yuki, Junya Hirokawa, Yoshio Sakurai
Graduate School of Brain Science, Doshisha University, Japan

1P-229Hippocampal-prefrontal plasticity with transcranial direct current
stimulation
Yumiko Watanabe1), Hiroyuki Takei1,2), Kazuaki Nagasaka1),
Ichiro Takashima1,2)

Human Informatics Research Institute, National Institute of Advanced Industrial
Science and Technology (AIST), Japan, 2Graduate School of Comprehensive Human
Sciences, University of Tsukuba, Japan1

1P-230D-galactose induced aging aggravates hippocampal oxidative stressin obese-insulin resistant rats
Thazin Shwe1,2,3), Cherry Bo-Htay1,2,3), Wasana Pratchayasakul1,2,3),
Nipon Chattipakorn1,2,3), Siriporn C Chattipakorn1,3,4)

Neurophysiology Unit, Cardiac Electrophysiology Research and Training Center,
Faculty of Medicine, Chiang Mai University, Thailand, 2Cardiac Electrophysiology Unit,
Department of Physiology, Faculty of Medicine, Chiang Mai University, Thailand, 3Centerof Excellence in Cardiac Electrophysiology, Chiang Mai University, Thailand,
4
Department of Oral Biology and Diagnostic Science, Faculty of Dentistry, Chiang Mai
University, Thailand
1

1P-231

Exercise, not calorie restriction, improves cognitive function in obese
rats
Wasana Pratchayasakul1,2,3), Duangkamol Mantor1,2,3), Wanitchaya Minta1,2,3),
Wissuta Sutham1,2,3), Siripong Palee1,3), Jirapas Sripetchwandee1,2,3),
Sasiwan Kerdphoo1,3), Thidarat Jaiwongkum1,3), Nipon Chattipakorn1,2,3),
Siriporn C Chattipakorn1,3,4)

Neurophysiology Unit, Cardiac Electrophysiology Research and Training Center,
Faculty of Medicine, Chiang Mai University, Thailand, 2Cardiac Electrophysiology Unit,

1

Neuroscience: Learning, memory & neuronal plasticity (1)Department of Physiology, Faculty of Medicine, Chiang Mai University, Thailand, 3Centerof Excellence in Cardiac Electrophysiology, Chiang Mai University, Thailand,
4
Department of Oral Biology and Diagnostic Sciences, Faculty of Dentistry, Chiang Mai
University, Thailand

1P-232

Mitochondrial ATP-linked respiration in PBMCs is associated withcognition in Aged-EGAT population

Center of Excellence in Cardiac Electrophysiology Research, Faculty of Medicine,
Chiang Mai University, Thailand, 2Neurophysiology Unit, Cardiac Electrophysiology
Research and Training Center, Faculty of Medicine, Chiang Mai University, Thailand,
3
Department of Oral Biology and Diagnostic Sciences, Faculty of Dentistry, Chiang Mai
University, Thailand, 4Department of Physiology, Faculty of Medicine, Chiang Mai
University, Thailand, 5Department of Internal Medicine, Faculty of Medicine, Chiang Mai
University, Thailand, 6Department of Medicine, Faculty of Medicine, Ramathibodi
Hospital, Mahidol University, Thailand
1

1P-233

Temporal dynamics of reward cue representation in the rat paraventricular nucleus
Munkhzaya Unur, Chinzorig Choijiljav, Jumpei Matsumoto,
Hiroshi Nishimaru, Yusaku Takamura, Taketoshi Ono, Hisao Nishijo
Department of System Emotional Science, University of Toyama, Japan

1P-234Modulation of Synaptic Plasticity in Hippocampal CA1 Region by
Basolateral Amygdala
Yee Song Chong1,2), Cai Shan Goh1), Sreedharan Sajikumar1,2)

Department of Physiology, School of Medicine, National University of Singapore,
Singapore, 2Neurobiology/Aging Program, Life Sciences Institute, Singapore

11P-235

Depotentiation at the hippocampal CA1 synapse depends on thebasal synaptic transmission
Jun-Ichi Goto1,2), Satoshi Fujii1,2), Kenya Kaneko1), Hiroki Fujiwara1),
Yoshihiko Yamazaki1), Katsuhiko Mikoshiba2)

1
Department of Physiology, Yamagata University School of Medicine, Japan, 2Laboratory
for Developmental Biology, Center for Brain Science, RIKEN, Japan

1P-236

Population Spike-Timing-Dependent Plasticity and Synaptic Tagging
and Capture in hippocampal CA1
Ka Lam Karen Pang1,2), Mahima Sharma1,2), Thomas Behnisch3),
Sreedharan Sajikumar1,2)

Department of Physiology, Yong Loo Lin School of Medicine, National University ofSingapore, Singapore , 2Neurobiology/Aging Programme, Life Sciences Institute, Centre
for Life Sciences, 3The Institutes of Brain Science, The State Key Laboratory of Medical
Neurobiology, The Collaborative Innovation Centre for Brain Science, Fudan University,
China

1

1P-237p75 neurotrophin receptor regulates hippocampal associative
plasticity in aging
Lik Wei Wong, Yee Song Chong, Sajikumar SreedharanDepartment of Physiology, National University of Singapore, Singapore

1P-238

Role of dopamine D3 receptor on hyper-dopamine activity-alterednovel object recognition memory
Jin-Chung Chen1,2), Pi-Kai Chang1,2)

Neuroscience: Learning, memory & neuronal plasticity (1)DAY 2

Sirawit Sriwichaiin1,2,4), Nattayaporn Apaijai1,2), Thidarat Jaiwongkam1,2),
Sasiwan Kerdphoo1,2), Wasana Pratchayasakul1,2,4), Siripong Palee1,2),
Arintaya Phrommintikul1,2,5), Chrigriya Kitiyakara6), Piyamitr Sritara6),
Nipon Chattipakorn1,2,4), Siriporn Chattipakorn1,2,3)

Department of Physiology and Pharmacology, School of Medicine, Chang-Gung
University, Taiwan, 2Graduate Institute of Biomedical Sciences, Chang-Gung University

1

1P-239

Role of olfactory tubercle in the weaning of neonatal mice
Yasutaka Chikuda, Masahiro Yamaguchi

Department of Physiology, Kochi Medical School, Japan

1P-240

The analysis of neuropsin-dependent and-independent late associativity
Yasuyuki Ishikawa, Yuka Suzuki

Department of Systems Life Engineering, Maebashi Institute of Technology, Japan

1P-241

Differentiation of spatially overlapping routes and reward zones in themonkey hippocampus
Rafael Bretas Vieira1,2), Jumpei Matsumoto2), Hiroshi Nishimaru2),
Yusaku Takamura2), Etsuro Hori2), Taketoshi Ono2), Hisao Nishijo2)

Laboratory for Symbolic Cognitive Development, Center for Biosystems Dynamics
Research, RIKEN, Japan, 2System Emotional Science, Graduate School of Medical andPharmaceutical Sciences, University of Toyama, Japan1

1P-242(-)-Festidinol: Potential Effect on Preventing Neurodegeneration in
Mice
Jittiporn Wongpun1), Ratchanaporn Chokchaisiri2), Jiraporn Tocharus3),
Apichart Suksamrarn4), Chainarong Tocharus1)

Department of Anatomy, Faculty of Medicine, Chiang Mai University, Thailand,
Department of Chemistry, Faculty of Science, University of Payao, Thailand,
3
Department of Physiology, Faculty of Medicine, Chiang Mai University, Thailand,
4
Department of Chemistry and Center of Excellence for Innovation in Chemistry,
Faculty of Science, Ramkhamhaeng University, Thailand
12

1P-243

Effect of agomelatine on neurogenesis in D-galactose-induced brain
aging
Teera Chanmanee1), Piyarat Govitrapong2), Jiraporn Tocharus3),
Chainarong Tocharus 1)

Department of Anatomy, Faculty of Medicine, Chiang Mai University, Thailand,
Chulabhorn Graduate Institute, Thailand, 3Department of Physiology, Faculty of
Medicine, Chiang Mai University, Thailand

12

1P-244

Effects of 5,6,7,4’-TMF on neurodegeneration and neurogenesis indexamethasone-induced mice
Kanet Pakdeepak1), Ratchanaporn Chokchaisiri2), Chainarong Tocharus3),
Pranglada Jearjaroen1), Apichart Suksamrarn4), Jiraporn Tocharus1)

Department of Physiology, Faculty of Medicine, Chiang Mai University, Thailand,
Department of Chemistry, School of Science, University of Phayao, 3Department of
Anatomy, Faculty of Medicine, Thailand , 4Department of Chemistry and Center of
Excellence for Innovation in Chemistry, Faculty of Science, Ramkhamhaeng University
1
2

Neuroscience: Higher order brain functions
1P-246

Salicylate-induced changes of tuning function in AI of guinea pigs
observed by optical recording.
Yutaka Hosokawa1), Michinori Kubota2), Shunji Sugimoto3),
Junsei Horikawa4)

1
Dept. of Systems Physiol., Grad. Sch. Univ. of Ryukyus, Japan, 2Med. Res. Inst., Tokyo
Medical and Dental Univ., 3Dept. of Comp. Sci. and Eng., Grad. Sch. of Eng., Toyohashi
Univ. of Technology, 4Senior Researcher, Toyohashi Univ. of Technology

Neuroscience: Learning, memory & neuronal plasticity (1)/Neuroscience: Higher order brain functions

1P-247

Laterality effects of the visual information processing on the sensorimotor gating system
Daisuke Ishii1,2), Kotaro Takeda3), Satoshi Yamamoto4), Akira Noguchi5),
Kiyoshige Ishibashi6), Kenya Tanamachi6), Arito Yozu1), Yutaka Kohno1)

Center for Medical Sciences, Ibaraki Prefectural University of Health Sciences, Japan,
Department of Cognitive Behavioral Physiology, Chiba University Graduate School of
Medicine, 3Faculty of Rehabilitation, School of Health Sciences, Fujita Health University,
4
Department of Physical Therapy, School of Healthcare, Ibaraki Prefectural University of
Health Sciences, 5Sakai Neurosurgical Clinic, 6Department of PhysicaI Therapy, Ibaraki
Prefectural University of Health Sciences Hospital1
2

Neural substrates of action timing decisions

Masayoshi Murakami1), Fanny Cazettes2), Zachary F. Mainen2),
Kazuo Kitamura1)
1
2

1P-249Department of Neurophysiology, Division of Medicine, University of Yamanashi, Japan,
Champalimaud Research, Champalimaud Centre for the Unknown, Portugal

Ongoing motor information embedded in a network dynamics ofprimate primary somatosensory neurons
Kei Mochizuki1), Katsumi Nakajima2), Masahiko Inase1), Akira Murata1)1Dept Physiol, Facult Med, Kindai Univ, Japan, 2Dept Physiol, Facult Med, Iwate Medical
Univ, Japan

1P-250Chronic mild stress increases aggressive behavior in mice

Sachiko Chikahisa, Tetsuya Shiuchi, Daisuke Tanioka, Noriyuki Shimizu,
Airi Otsuka, Hiroyoshi Sei
Department of Integrative Physiology, Institute of Biomedical Sciences, Tokushima
University Graduate School, Japan

1P-251

Body ownership and agency altered by a robotic arm controlled byelectromyography of elbow muscles
Toshihiro Kawase1,2,3), Kenta Kono1), Kenichi Cho1), Eiko Kato1),
Kenji Kansaku1,4)

Department of Physiology and Biological Information, Dokkyo Medical University
School of Medicine, Japan, 2Institute of Biomaterials and Bioengineering, Tokyo Medical
and Dental University, Japan, 3Institute of Innovative Research, Tokyo Institute ofTechnology, Japan, 4Brain Science Inspired Life Support Research Center, The University
of Electro-Communications, Japan1

1P-252

Hypoxia effect on daily activity is daily activity dependent wavelike
response in mice
Satoru Masubuchi1), Takako Yano1), Kouji Komatsu1), Wataru Nakamura2),
Akinobu Ota3), Sivasundaram Karnan3), Kosei Takeuchi4),
Yoshitaka Hosokawa3), Takeshi Todo5), Toshiaki Shiomi6)1
Department of Physiology, Aichi Medical University, Japan, 2Department of Oral
ChronoPhysiology, Unit of Basic Medical Sciences, Graduate School of Biomedical
Sciences, Nagasaki University, Japan, 3Department of Biochemistry, Aichi Medical
University, Japan, 4Department of Biology, Aichi Medical University, Japan , 5Departmentof Radiation biology and Medical Genetics, Graduate School of Medicine, Osaka
University, Japan, 6Department of Sleep Medicine, Aichi Medical University, Japan

1P-253

Recency of pattern repetition degrades monkeys’ performance inpattern recognition with visual noise
Ryosuke Kuboki1), Narihisa Matsumoto2), Yasuko Sugase-Miyamoto2),
Barry J Richmond3), Munetaka Shidara1,4)

Grad. Sch. of Comprehensive Human Sci., University of Tsukuba, Japan, 2Human Info.

1

Neuroscience: Higher order brain functions

DAY 2

1P-248

Res. Inst. & AIRC, AIST, Japan, 3NIMH/NIH, Bethesda, MD, USA, 4Faculty of Medicine,
University of Tsukuba, Japan

1P-255Lower c-Fos expressions in the posterior parietal cortex during rubber
tail task in Caps2 KO mice
Makoto Wada1,2), Masakazu Ide1), Takeshi Atsumi1), Kouji Takano3),
Yoshitake Sano4), Yo Shinoda5), Teiichi Furuichi4), Kenji Kansaku3,6,7)

1
Dev Disorders Sect, Dept Brain Rehab, Res Inst of NRCD, Japan, 2Dept Informatics,
Shizuoka Univ, 3Sys Neurosci Sect, Dept Brain Rehab, Res Inst of NRCD, 4Tokyo Univ of
Sci, 5Tokyo Univ of Pharmacy and Life Science, 6Brain Sci Inspired Life Supp Res Cent,
Univ of Electro-Communications, 7Dept Physiol & Biol Info, Dokkyo Med Univ Sch ofMed

1P-256

Interval timing of visual and auditory cues for duration discriminationin monkey prefrontal cortex
Atsushi Chiba1), Kazunori Morita2), Ken-ichi Oshio1), Masahiko Inase1)

Department of Physiology, Kindai University, Japan, 2Department of Physiology, Iwate
Medical University, Japan1

1P-257

Haptic material perception in macaque monkeys, estimated by thematerial discrimination task
Minami Ito, Chisaki Hatta, Sakie Yoshida, Kanoko Katsube, Yuka Morisue,Tensei Iwata

Department of Biofunctional System Engineering, Tokyo Medical and Dental University(TMDU), Japan

1P-258

Physiological effects of two types of sitting positions on the brain andautonomic nerve activities
Yuji L. Tanaka1), Yume Sasaki2), Ayumi Amemiya1), Hisayoshi Sugawara1),
Ryutaro Kase1)

Department of Nursing Physiology, Chiba University Graduate School of Nursing,Japan, 2Yokohama Municipal Citizen's Hospital, Japan1

1P-259Prefrontal-enriched SLIT1 expression in primate cortex establishedduring the postnatal development
Tetsuya Sasaki1,2), Yusuke Komatsu3), Akiya Watakabe4), Tetsuo Yamamori4)

Department of Anatomy and Neuroscience, Faculty of Medicine, University of Tsukuba,
Japan, 2Department of Kansei, Behavioral, and Brain Sciences, Graduate School ofComprehensive Human Sciences, 3ACD Corporation, 4Laboratory for Molecular Analysisof Higher Brain Function, CBS, RIKEN
1

1P-260

Response preference to artificial and environmental natural sounds
in higher auditory cortices
Sohei Chimoto

Department of Neurophysiology, University of Yamanashi, Japan

1P-261

Neural properties of macaque SII bimodal neurons and their functionalrole for self-body awarenessMiki Taoka, Sayaka Hihara, Rafael Bretas, Atsushi Iriki

Laboratory for Symbolic Cognitive Development, Center of Biosystematics Dynamics
Research, RIKEN, Japan

Neuroscience: Higher order brain functions

Neuroscience: Neurologic and psychiatric diseases (1)1P-262

The relation between the NMDA receptor/NO/cGMP pathway and theantidepressant-like effects of GLP-2
Sachie Sasaki-Hamada1,2), Yuya Nakamura2), Kenichi Koizumi2),
Rena Nabeta2), Jun-Ichiro Oka2)

1P-263

Systematic analysis on the seeding activity of familial mutant forms of
α-synuclein
Ning Xu1), Genta Ito2), Airi Tarutani1), Taisuke Tomita1,2)

Laboratory of Neuropathology and Neurosciences, Graduate School of Pharmaceutical
Science, The University of Tokyo, Japan, 2Laboratory of Brain and Neurological Disorders,
Graduate School of Pharmaceutical Science, The University of Tokyo, Japan1

1P-264

Olfactory impairment associated with left hippocampus volumes at
earliest stages of schizophrenia
Yuri Masaoka1,2), Dennis Velakoulis2), Warrick Brewer3), Vanessa Cropley2),
Cali Bartholomeusz2,3), Masahiko Izumizaki1), Patrick Mcgorry3),
Stephen J Wood3,4), Christos Pantelis2,5)1
Department of Physiology, Showa University School of Medicine, Japan, 2Melbourne
Neuropsychiatry Centre, Department of Psychiatry, University of Melbourne andMelbourne Health, Australia, 3Orygen Youth Health Research Centre, Centre for YouthMental Health, University of Melbourne, Australia, 4School of Psychology, University ofBirmingham, UK, 5Centre for Neural Engineering, Department of Electrical andElectronic Engineering, University of Melbourne, Australia

1P-265Atypical Motility Patterns in Gut Preparation of LRRK2 Knockout
Mice
Tatsunori Maekawa1), Fumitaka Kawakami1), Rei Kawashima1),
Joel Bornstein2), Jaime Foong2), Takafumi Ichikawa1)

Department of Regulation Biochemistry, Graduate School of Medical Sciences,
Kitasato University, Japan, 2Department of Physiology, The University of Melbourne,
Australia
1

1P-266

Histone Deacetylase 1, 3 as a novel target for anti-seizure drug discovery
Kingsley Ibhazehiebo1,3), Cezar Gavrilovici2,3), Cristiane De La Hoz1,3),
Paola Meza Santoscoy1,3), Jong Micheal Rho2,3), Deborah Marie Kurrasch1,3)

1Department of Medical Genetics, University of Calgary, Canada, 2Department ofPediatrics, University of Calgary, Canada, 3Alberta Children’s Hospital Research Institute,
University of Calgary, Canada

1P-267Hyperventilation test with indocyanine green kinetics predicts
cerebral hyperperfusion after CAS
Ichiro Nakagawa, Masashi Kotsugi, Fumihiko Nishimura, Syuichi Yamada,Yasushi Motoyama, Young Su Park, Hiroyuki Nakase
Department of Neurosurgery, Nara Medical University, Japan

1P-268

Electrophysiological study of epilepticus recovering effect andmechanism of JBPOS0101 using MEA
Eunsang Hwang4), Kwan-Joong Kim3), Min-Jeong Kim3), Jeong-Hee Yoon1),
Jae-Ho Khil2), Ji-Ho Park1)

Department of East-West Medicine, Graduate School of East-West Medical Science,
Kyung Hee University, Korea, 2Department of Sports Medicine, Graduate School ofSports Science, Kyung Hee University, Korea, 3Department of Food Science andBiotechnology, Graduate School of Biotechnology, Kyung Hee University, Korea,

1

Neuroscience: Neurologic and psychiatric diseases (1)

DAY 2

1
Department of Physiology, Kitasato University, Japan, 2Laboratory of Pharmacology,
Tokyo University of Science, JapanDepartment of Gerontology, Graduate School of East-West Medical Science, Kyung
Hee University, Korea

4

1P-269

ROS generation, Neuronal degeneration and Neurologic dysfunction
after Ischemic Stroke in Mice
Nobuo Nagai1), Yasuki Matano1), Riku Kawazu1), Yasuhiro Suzuki2),
Kazuo Umemura3)

Laboratory of Animal Physiology, Nagahama Institute of Bio-Science and Technology,
Japan, 2School of Pharmaceutical Sciences, Ohu University, Japan, 3Department ofPharmacology, Hamamatsu University School of Medicine, Japan1

1P-270Effect of orexin on the firing pattern of serotonergic dorsal raphe
neurons
Masaru Ishibashi1,2), Nancy E Molina2), Atsuo Fukuda1),
Christopher S Leonard2)
1
2

1P-271

Department of Neurophysiology, Hamamatsu University School of Medicine, Japan,
Department of Physiology, New York Medical College

Would skin resistance be a novel neurophysiological marker fortranscranial electrical stimulation?
Hanna Lu1,2,3), Harriet Tang1), Linda Chiu Wa Lam1)

1
Department of Psychiatry, The Chinese University of Hong Kong, China, 2Shenzhen
Research Institute, The Chinese University of Hong Kong, 3The Affiliated Brain Hospitalof Guangzhou Medical University

1P-272

Proposal for the classification sweating disorders based on lesion
site
Yoko Inukai, Satoshi Iwase, Motohiko Sato

Department of Physiology, Aichi Medical University School of Medicine, Japan

1P-273

Reduced synaptic inputs in prefrontal cortex by lack of a mental
disorder-related epigenetic factor
Kenichiro Nagahama1,2), Kazuto Sakoori1,2), Takaki Watanabe1,2),
Naofumi Uesaka1,2), Masanobu Kano1,2)1Dept. Neurophysiol, Gran. Sch. of Med., The Univ Tokyo, Japan, 2WPI-IRCN, URIAS, The
Univ. Tokyo

1P-274

Common behavioral characteristics in the mice maternally exposed
to different types of dioxins
Fumihiko Maekawa1), Eiki Kimura1,2), Naoto Uramaru3), Go Suzuki4)

Center for Health and Environmental Risk Research, National Institute for Environmental
Studies, Japan, 2Japan Society for the Promotion of Science, 3Nihon Pharmaceutical
University, 4Center for Material Cycles and Waste Management Research, National
Institute for Environmental Studies, Japan1

1P-275TSPO-targeting compound ameliorates the abnormal behaviors ofmice received social defeat stress
Kanako Nozaki1), Hikaru Ito1), Masahiro Ohgidani2), Yosuke Yamawaki3),
Takashi Kitajima4), Seishi Katsumata4), Shigeto Yamawaki5), Takahiro Kato2),
Hidenori Aizawa1)

Department of Neurobiology, Hiroshima University, Japan, 2Department of
Neuropsychiatry, Kyushu University, Japan, 3Department of Cellular and Molecular
Pharmacology, Hiroshima University, Japan, 4Discovery Research Laboratories, Drug
Discovery Division, Discovery & Research ONO Pharmaceutical Co., Ltd., Japan,
5
Department of Psychiatry and Neurosciences, Hiroshima University, Japan1

1P-276

Investigation of the effect of seaweed on the metabolic dysfunctionassociated neurodegeneration
Neuroscience: Neurologic and psychiatric diseases (1)Motoki Imai1), Fumitaka Kawakami1), Hiroko Maruyama2)
Department of Regulation Biochemistry, Graduate School of Medical Sciences,
Kitasato University, Japan, 2Department of Cytopathology, Graduate School of Medical
Science, Kitasato University

1

1P-277The expression and activation of Smad in the rat hippocampus
following global cerebral ischemia
Yusuke Takahashi, Takayuki Nakajima

1P-278Abnormalities in synaptic structure and function in valproate-induced
autism model marmosets
Satoshi Watanabe1), Tohru Kurotani2), Tomofumi Oga1), Keiko Nakagaki1),
Jun Noguchi1), Noritaka Ichinohe1,2)

Department of Ultrastructural Research, National Center of Neurology and Psychiatry,
Japan, 2Ichinohe Group, Laboratory for Molecular Analysis of Higher Brain Function,
RIKEN Center for Brain Science, Japan1

1P-279Neonatal dexamethasone treatment suppresses hippocampal ERa
expression in adolescent female rats
Kwok-Tung Lu1), Hui-Fang Chiu1), Michael W.Y. W.Y Chan2),
Chiung-Yin Cheng1), Jian-Liang Chou3), Jora Meng-Ju Lin2), Yi-Ling Yang4)

Department of Life Science, University of Taiwan Normal University, Taiwan,
Department of Life Science, National Chung Cheng University, Taiwan, 3Division of
Gastroenterology, Chang Gung Memorial Hospital, Taiwan, 4Institute of Biochemical
Science and Technology, National Chia-Yi University, Taiwan

12

1P-280Rosmarinic acid protects against MPTP-induced toxicity and inhibits
iron-induced α-syn aggregation
Wenting Jia, Le Qu, Huamin Xu, Junxia Xie

Department of Physiology, Medical College of Qingdao University, China

1P-281

Automated, closed-loop stimulation of the medial septum alleviates
temporal lobe epilepsy in rats
Yuichi Takeuchi1,2), Márk Harangozó1), Lizeth Pedraza1), Tamás Földi1),
Gábor Kozák1), Antal Berényi1,3)

MTA-SZTE ‘Momentum’ Oscillatory Neuronal Networks Research Group, Departmentof Physiology, University of Szeged, Hungary, 2Department of Neuropharmacology,
Graduate School of Pharmaceutical Sciences, Nagoya City University, Japan,
3
Neuroscience Institute, New York University, USA
1

1P-282The effect of anti-arrhythmic drugs on glioma stem cells

Kohei Ofune1), Ryoichi Iwata1), Mikio Hayashi2), Kunikazu Yoshimura1),
Masahiro Nonaka1), Akio Asai1)

1
Department of Neurosurgery, Kansai Medical University, Japan, 2Department of Cell
Physiology, Kansai Medical University, Japan

1P-283

TRPV4 is critical to brain edema after traumatic brain injury

Yi-Ling Yang1), Kwok-Tung Lu2), Tai-Chung Huang2), Ya‐Hsin Tsai2)
Department of Biochemical Science and Technology, National Chia-Yi University,
Taiwan, 2Department of Life Science, National Taiwan Normal University, Taiwan

1

1P-284Three-dimensional kinematical gait analysis of hindlimbs in rats withfocal cerebral infarction
Tatsuro Kumada1), Akira Yoshikawa2), Saho Morishita3,4),
Kazuya Hokamura5), Masahiko Izumizaki2), Kazuo Umemura3)

Faculty of Health and Medical Sciences, Tokoha University, Japan, 2Department of
Physiology, Showa University, School of Medicine, Japan, 3Department of Pharmacology,

1

Neuroscience: Neurologic and psychiatric diseases (1)DAY 2

Department of Veterinary Anatomy, Osaka Prefecture University, Japan

Hamamatsu University School of Medicine, Japan, 4Faculty of Health Promotional
Sciences, Tokoha University, Japan, 5Department of Medical Education, Hamamatsu
University School of Medicine, Japan

1P-285

TrkB activation promotes neuronal survival via Akt-ASK1 signaling
after intracerebral hemorrhage
Chun-Hu Wu1), Yen-Chieh Chuang2), Chien-Cheng Chen3), Chia-Hua Ke3),
Chun-Yen Lee3), Song-Kun Shyue4), Szu-Fu Chen2,3)

Graduate Institute of Life Sciences, National Defense Medical Center, Taiwan,
Departments of Physiology and Biophysics, National Defense Medical Center, Taiwan,
Republic of China, 3Department of Physical Medicine and Rehabilitation, Cheng Hsin
General Hospital, Taiwan, Republic of China, 4Institute of Biomedical Sciences, Academia
Sinica, Taiwan, Republic of China
12

1P-286

Neuroprotective effects of COPPIX against dopaminergic neurons
degeneration in MPTP-intoxicated mice
Ning Song, Xiaofeng Xu, Xiaojun Yu, Junxia Xie
Department of Physiology, Qingdao University, China

1P-287

Investigation of the antidepressant agomelatine and ketamine on thesynaptic plasticity in mice
Chi-Wei Lee1,2), Yueh-Jung Chung2), Yi-Chao Lee1), Hui-Ching Lin1,2,3)

Ph.D. Program for Neural Regenerative Medicine, College of Medical Science andTechnology, Taipei Medical University, Taiwan, 2Department and Institute of Physiology,
School of Medicine, National Yang-Ming University, Taiwan, 3Brain Research Center,
National Yang-Ming University, Taiwan

1

1P-288Prenatal stress on Gad1-heterozygotes perturbs development of
GABAergic networks affecting behavior
Tianying Wang1), Adya Saran Sinha1), Hiroki Mutoh1), Tenpei Akita1),
Yuchio Yanagawa2), Tomoko Kawai3), Kenichiro Hata3), Atsuo Fukuda1)

Department of Neurophysiology, Hamamatsu University School of Medicine, Japan,
Department of Genetic and Behavioral Neuroscience, Gunma University Graduate
School of Medicine, Japan, 3Department of Maternal–Fetal Biology, National ResearchInstitute for Child Health and Development, Japan
1
2

1P-289Suppression of FoxO1 by leptin enhances tyrosine hydroxylase andleads to anxiolytic behavior
Seul Ki Kim1), Dong Hwee Son1), Khanh Van Doan2), Dong Joo Yang1,3),
Ji Su Sun1), Yun-Hee Choi1), Dong Min Shin1), Ki Woo Kim1)

Department of Oral Biology, BK21 PLUS Project, Yonsei University College of Dentistry, Korea, 2Department of Pharmacology, School of Medicine, Tan Tao University, Vietnam.,Department of Pharmacology and Global Medical Science, Yonsei University, Republicof Korea1

3

Neuroscience: Somatosensory & Pain (1)1P-290

Nociceptor-mediated outcomes under hydroxyphenyl octanediamide
exposure via TRPV4 modulation
Pyung Sun Cho1,2), Geunyeol Choi1), Minseok Kim1), Seung-In Choi1),
Ji Yeon Lim1), Im Joo Rhyu1), Sun Wook Hwang1,2)

Department of Biomedical Sciences, Korea University, Korea, 2 Neuroscience ResearchInstitute, Korea University, Korea

1

1P-291

Effects of Toxoplasma gondii infection on motor and non-motor
symptoms of rat model of Parkinson
Mahnaz Taherianfard, Moslem Riyahi

Neuroscience: Somatosensory & Pain (1)/Neuroscience: Somatosensory & Pain (1)Physiology Division of Basic Science Department, Shiraz University, Iran

1P-292

Increase of histone acetylation in the RVM in the rat with stressinduced hyperalgesia
Hiroki Imbe, Akihisa Kimura

Department of Physiology, Wakayama Medical University, Japan

1P-293

Masayuki Kurose1), Mana Hasegawa2), Yosuke Nakatani1,3), Shiho Shimizu1,3),
Noritaka Fujii2), Yoshihide Satoh4), Kensuke Yamamura1),
Keiichiro Okamoto1)

Division of Oral Physiology, Department of Oral Biological Sciences, Niigata University,
Graduate School of Medical and Dental Sciences, Japan, 2General Dentistry and Clinical
Education Unit, Niigata University Medical and Dental Hospital, Japan, 3Division of Oraland Maxillofacial Surgery, Department of Oral Biological Sciences, Niigata University,
Graduate School of Medical and Dental Sciences, Japan, 4Department of Physiology,
The Nippon Dental University School of Life Dentistry at Niigata, Japan1

1P-294

Descending orexinergic inhibition contributes to the linalool odorinduced analgesia in mice
Yurina Higa1,2), Mitutaka Sugimura1), Tomoyuki Kuwaki2),
Hideki Kashiwadani2)

Department of Dental Anesthesiology, Graduate School of Medical and Dental
Sciences Kagoshima University, Japan, 2Department of Physiology, Graduate School of
Medical and Dental Sciences Kagoshima University

1

1P-295Modulation of nociception via Endothelin-1 signaling in early-stage
tongue cancer in rats
Masamichi Shinoda1), Akihiko Furukawa2), Ryuta Akasaka2),
Yoshiyuki Yonehara2), Koichi Iwata1)

1
Department of Physiology, Nihon University School of Dentistry, Japan, 2Departmentof Clinical Medicine, Nihon University School of Dentistry, Japan

1P-296

TRPV1 Expression in the TG and Spinal Trigeminal Nucleus Following Dental Pulp Inflammation
Myeounghoon Cha1), Imene Sallem2), Il-Young Jung2), Bae Hwan Lee1)

1
Department of Physiology, Yonsei University College of Medicine, Korea, 2Departmentof Conservative Dentistry and Oral Science Research Center, Yonsei University Collegeof Dentistry

1P-297

TRPV1 inhibition by α2 adrenergic receptors on peripheral sensory
neurons causes analgesia
Yumi Matsushita, Miki Manabe, Naoki Kitamura, Izumi Shibuya
Faculty of Agriculture, Tottori University, Japan

1P-299Effects of QX314 / Flagellin (Q/F) on the conduction of the peripheral
nerve in rats
Yoshiyuki Tsuboi, Akihiro Kaizu

Department Physiology, Nihon University School of Dentistry, Japan

1P-300Investigation of the antipruritic mechanisms of nalfurafine in themurine spinal cord
Kotaro Honda1), Mitsutoshi Tominaga1), Fumiya Kusube1,2),
Fumiyuki Yamakura3), Hisashi Naito4), Yasushi Suga5), Kenji Takamori1,5)
12

Institute for Environmental and Gender Specific Medicine, Juntendo University, Japan,
Department of Biological Science and Technology, Faculty of Industrial Science and
Neuroscience: Somatosensory & Pain (1)DAY 2

Psychological stress modulates On- and Off-cell activity in the rostral
ventromedial medulla

Technology, Tokyo University of Science, Japan, 3Faculty of International Liberal Arts,
Juntendo University, Japan, 4Institute of Health and Sports Science & Medicine,
Juntendo University, Japan, 5Department of Dermatology, Juntendo University Urayasu
Hospital, Japan

1P-301

Enhanced basal pain sensitivities observed in mice lacking interleukin-27
Toshiharu Yasaka1), Tomoko Sasaguri2), Toru Taguchi3,4), Yuzo Murata5),
Kimiko Kobayashi6), Sayaka Iizasa7), Ei’ichi Iizasa1), Makoto Tsuda8),
Naomi Hirakawa2), Hiromitsu Hara1), Hiroki Yoshida9)

Department of Immunology, Kagoshima University, Japan, 2Department ofAnesthesiology & Critical Care Medicine, Saga University, Japan, 3Department of
Physical Therapy, Niigata University of Health and Welfare, Japan, 4Department of
Neuroscience II, Nagoya University, Japan, 5Division of Histology and Neuroanatomy,
Department of Anatomy & Physiology, Saga University, Japan, 6Department of Anatomy
and Neuroscience, Hyogo College of Medicine, Japan, 7Department of Biological
Science and Technology, Kagoshima University, Japan, 8Department of Molecular and
System Pharmacology, Kyushu University, Japan, 9Division of Molecular and Cellular
Immunoscience, Department of Biomolecular Sciences, Saga University, Japan1

1P-302

Withdrawn

1P-303Astrocytes are a novel target for treatment of the chronic pain
Ikuko Takeda, Kei Eto, Kohei Yoshihara, Junichi Nabekura

Division of Homeostatic Development, National Institute for Physiological Sciences,Japan

1P-304IFN-γ signaling in trigeminal spinal subnucleus caudalis is involved inorofacial neuropathic pain
Sayaka Asano1,2), Masamichi Shinoda2), Akiko Ogawa-Okada1),
Yoshiki Imamura1), Koichi Iwata2)12

1P-305

Department of Oral Diagnostic Sciences, Nihon University School of Dentistry, Japan,
Department of Physiology, Nihon University School of Dentistry, Japan

Analgesic effects of calcitonin on radicular pain in rats

Yoshinori Terashima1,2), Shunsuke Jimbo2), Tatsuya Sato1),
Nobutoshi Ichise1), Toshihiko Yamashita2), Noritsugu Tohse1)

Department of Cellular Physiology and Signal Transduction, Sapporo Medical
University School of Medicine, Japan, 2Department of Orthopaedic Surgery, Sapporo
Medical University School of Medicine, Japan1

1P-306

Effect of intraarticular hyaluronic acid in a rat monoiodoacetateinduced ankle osteoarthritis model
Shunsuke Jimbo1,2), Yoshinori Terashima1,2), Atsushi Teramoto2),
Tatsuya Sato1), Izaya Ogon2), Nobutoshi Ichise1), Kota Watanabe3),
Tsuneo Takebayashi4), Toshihiko Yamashita2), Noritsugu Tohse1)

Department of Cellular Physiology and Signal Transduction, Sapporo Medical
University School of Medicine, Japan, 2Department of Orthopedic Surgery, Sapporo
Medical University School of Medicine, Japan, 3Department of Second Division of
Physical Therapy, Sapporo Medical University School of Health Sciences, Japan ,4
Sapporo Maruyama Orthopaedic Hospital, Japan1

1P-307Chronic pain model alters GABAergic synaptic transmission in themice anterior cingulate cortex
Kohei Koga1,2), Shuji Shimoyama1), Akihiro Yamada2), Hidemasa Furue2),
Kazuhiko Nakamura3), Shinya Ueno1)
Department of Neurophysiology, Hirosaki University, Japan,

1

Neuroscience: Somatosensory & Pain (1)2

Department ofNeurophysiology, Hyogo College of Medicine, Japan, 3Research Center for Child Mental
Development, Hirosaki University, Japan

1P-308NGF induces constitutive activity of TRPV1 triggering spontaneous
firing in sensory neurons
Naoki Kitamura, Erika Nagami, Yumi Matsushita, Tomohiko Kayano,
Izumi Shibuya
Faculty of Agriculture, Tottori University, Japan

Characterization of mechanically-insensitive afferents and sympathetic efferents in skeletal muscle
Hiroki Ota1), Takanori Matsubara2), Harumi Hotta3), Kazue Mizumura4),
Toru Taguchi5)1Dept. Judo Ther., Fac. Med. Tech., Teikyo Univ., Japan, 2Dept. Neural Regul., Grad. SchoolMed., Nagoya Univ., Japan, 3Dept. Auton. Neurosci., Tokyo Metropol. Inst. Gerontol.,
Japan, 4Dept. Phys. Sch. Dent. Nihon Univ., Japan, 5Dept. Phys. Ther., Fac. Rehabil.,
Niigata Univ. Health Wel., Japan

1P-310An alteration of gut microbiota is associated with pain in fibromyalgia
patients: a pilot study
Passakorn Sawaddiruk1), Nattayaporn Apaijai2), Sasiwan Kerdphoo2),
Nipon Chattipakorn3), Siriporn Chattipakorn2)

Department of Anesthesiology, Faculty of Medicine, Chiang Mai University, Thailand,
Neurophysiology Unit, Cardiac Electrophysiology Research and Training Center,
Faculty of Medicine, Chiang Mai University, Thailand, 3Center of Excellence in Cardiac
Electrophysiology Research, Chiang Mai University, Thailand
12

1P-311

In vivo two-photon imaging of thermo-sensing at the skin of living rats
Atsunori Kamiya1), Kazuo Kobayashi2)

Department of Cellular Physiology, Graduate School of Medicine, Dentistry andPharmaceutical Sciences, Okayama University, Japan, 2Department of Molecular
Genetics, Institute of Biomedical Sciences, Fukushima Medical University School of
Medicine
1

1P-312

Cisplatin-induced intraoral neuropathy due to TRPA1 sensitization inrats
Suzuro Hitomi1), Kiichiro Yamaguchi1), Yuji Seta2), Izumi Ujihara1),
Kentaro Ono1)

1
Division of Physiology, Kyushu Dental University, Japan, 2Division of Anatomy, Kyushu
Dental University

1P-313

Amitriptyline-induced suppression of spinal dorsal horn neurons in a
rat model of fibromyalgia
Toru Taguchi1), Daisuke Uta2), Katsuyuki Tsuboshima3), Hisao Nishijo3),
Kazue Mizumura4)

Department of Physical Therapy, Niigata University of Health and Welfare, Japan,
Department of Applied Pharmacology, Graduate School of Medicine andPharmaceutical Sciences, University of Toyama, Japan, 3System Emotional Sciences,
Graduate School of Medicine and Pharmaceutical Sciences, University of Toyama,
Japan, 4Department of Physiology, School of Dentistry, Nihon University, Japan1
2

1P-314Presynaptic inhibition of muscle afferent in awake, behavingmonkeys: task-dependent modulation
Saeka Tomatsu1,2), Geehee Kim2), Shinji Kubota2), Kazuhiko Seki2)

Department of System Neuroscience, National Institute for Physiological Science,
Japan, 2Department of Neurophysiology, National Institute of Neuroscience, National
Center of Neurology and Psychiatry, Japan1

Neuroscience: Somatosensory & Pain (1)DAY 2

1P-309

1P-315

Tentonin 3/TMEM150c, a mechanotransduction channel for Arterialpressure sensing baroreceptors
Huanjun Lu1,2), Luan Thien Nguyen1,2), Hyungsup Kim1), Hyesu Kim1),
Uhtaek Oh1)
1
2

1P-316

Brain Science Institute, Korea Institute of Science and Technology (KIST), Korea,
College of Pharmacy, Seoul National University, Korea

The role of Cdkal1-mediated tRNA modification in peripheral neuropthy
Korin Sakakida1,2), Fan-Yan Wei1), Eiichi Araki2), Kazuhito Tomizawa1)

Department of Molecular Physiology, University of Kumamoto, Japan, 2Department ofMetabolic Medicine, University of Kumamoto, Japan1

1P-317

Mild traumatic brain injury induce sensitization of neurovascularsystem: Relevance for migraine
Akimasa Tashiro, Hiroyuki Ohta, Yuji Morimoto

Department of Physiology, National Defense Medical College, Japan

1P-318Mechanical and reactive oxygen species-sensitive TRP channels
mediate tooth movement-induced pain
Aoi Morii1,2), Suzuro Hitomi1), Izumi Ujihara1), Misa Sago-Ito2),
Masahiro Mizuhara2), Kaori Gunjigake2), Tatuo Kawamoto2), Kentaro Ono1)

Division of Physiology, Kyushu Dental University, Japan, 2Division of Orofacial Functions
and Orthodontics, Kyushu Dental University, Japan1

1P-319Therapeutic effects of highly-residual ointments on oral ulcerativemucositis
Mako Naniwa1,2), Suzuro Hitomi1), Izumi Ujihara1), Kazunari Matsuda3),
Kenichi Yoshino4), Atsuko Nakamichi2), Kentaro Ono1)

1
Division of Physiology, Kyushu Dental University, Japan, 2Division of Oral Health
Sciences, Kyushu Dental University, Japan, 3Daiichi Sankyo Healthcare Co. Ltd., Japan,
4
Section of Primary Dental Education, Kyushu Dental University, Japan

1P-320mGluR5 in the dysgranular zone of primary somatosensory cortex
mediates neuropathic pain in the rat
Geehoon Chung1,2), Sang Jeong Kim2), Sun Kwang Kim1)
12

1P-321

Department of Physiology, College of Korean Medicine, Kyung Hee University, Korea,
Department of Physiology, College of Medicine, Seoul National University, Korea

Thermosensory processing in excitatory and inhibitory neurons of the
primary somatosensory cortex
Kei Eto, Junichi Nabekura

Division of Homeostatic Development, National Institute for Physiological Sciences,Japan

Neuroscience: Somatosensory & Pain (1)Neuroscience: Autonomic Physiology (1)1P-322

Electrophysiological characterization of bradykinin B2 receptors in rat
intracardiac neurons
Shiho Arichi1), Sachie Hamada2), Masanori Ogata2), Hitoshi Ishibashi2)

Department of Brain Science, Graduate School of Medical Science, Kitasato University,
Japan, 2Department of Physiology, School of Allied Health Science, Kitasato University,
Japan
1

Cell type-based activation timing and order in the sequence in the
preBotzinger Complex
Yoshihiko Oke1), Fumikazu Miwakeichi2,3), Yoshitaka Oku1),
Johanness Hirrlinger4,5), Swen Hülsmann6,7)

Division of Physiome, Department of Physiology, Hyogo College of Medicine, Japan,
Department of Statistical Modeling, The Institute of Statistical Mathematics, Japan,
3
Department of Statistical Science, School of Multidisciplinary Sciences, The Graduate
University for Advanced Studies, Japan, 4Carl-Ludwig-Institute for Physiology, Faculty of
Medicine, University of Leipzig, Germany, 5Department of Neurogenetics, Max Planck
Institute of Experimental Medicine, Germany, 6Clinic for Anesthesiology, University
Medical Center Gottingen, Germany, 7Research Center for Nanoscale Microscopy andMolecular Physiology of the Brain, University Medical Center Gottingen, Germany
12

1P-324

Respiratory fluctuations in pupil diameter are not maintained duringcognitive tasks
Nozomu H Nakamura1), Masaki Fukunaga2), Yoshitaka Oku1)

Div. Physiome, Dept. Physiology, Hyogo College of Medicine, Japan, 2Div. Cerebral
Integration, Dept. System Neuroscience, National Institute of Physiological Sciences,
Japan

1

1P-325Morphology and vanilloid-susceptibility of sensory neurons inner­vating perirenal adipose tissue
Bo-Xun Liu, Peng-Yu Zong, Xu-Guan Chen, Wei Sun, Xiang-Qing Kong

Department of Cardiology, The First Affiliated Hospital of Nanjing Medical University,
China

1P-326The central nNOS uncoupling contributes to cardiovascular dys­function in hypertensive rats
Wei-Zhong Wang, Xing Tan, Yang-Kai Wang, Ya-Hong Yang
Department of Physiology, Naval Medical University, China

1P-327Involvement of PVN neurons projecting to the RVLM in sympathetic
dysfunction in heart failure
Satoshi Koba, Eri Hanai, Nao Kumada, Tatsuo Watanabe
Tottori University Faculty of Medicine, Japan

1P-328

Responses to hypercapnia and hypoxia of Phox2b-positive cells inthe ventral medulla of newborn rats
Hiroshi Onimaru1), Keiko Ikeda2), Hiroyuki Igarashi3), Hiromu Yawo4),
Kazuto Kobayashi5), Satoru Arata6), Kiyoshi Kawakami7),
Masahiko Izumizaki1)

1
Department of Physiology, Showa University School of Medicine, Japan, 2Departmentof Physiology, International University of Health and Welfare (IUHW), 3Department of
Physiology and Pharmacology, Schulich School of Medicine and Dentistry, Robarts
Research Institute, Western University, 4Department of Integrative Life Sciences, Tohoku
University Graduate School of Life Sciences, 5Dept Mol Genet, (Inst Bio Sic,) Fukushima
Med Univ, 6Center for Biotechnology, Showa University, 7Division of Biology, Center for
Molecular Medicine, Jichi Medical University

Neuroscience: Autonomic Physiology (1)DAY 2

1P-323

1P-329

Involvement of the lateral parabrachial nucleus in the pressor
responses to pinching of the hindpaw
Hana Nozawa1,2), Rie Shimoju1,3), Takamichi Taniguchi1,2), Hideshi Shibata4),
Mieko Kurosawa1,5)

Grad. Sch. Health & Sci., Int. Univ. Health & Welfare, Japan, 2Dept. Occupational Ther.,Intl. Univ. Health & Welfare, Japan, 3Dept. Physical Ther., Intl. Univ. Health & Welfare,Japan, 4Lab. Vet. Anat., Ins. Agric., Tokyo Univ. Agric & Tech., Japan, 5Center Med. Sci., Intl.
Univ. Health & Welfare, Japan1

1P-330Raphe-projecting oxytocinergic hypothalamic neurons stimulate
brown adipose tissue thermogenesis
Akihiro Fukushima, Kazuhiro Nakamura

Department of Integrative Physiology, Nagoya University Graduate School of Medicine,Japan

1P-331Strychnine enhances inspiratory-related calcium rise in the thoracic
inspiratory interneuron
Yoshihiro Mikami, Makito Iizuka, Hiroshi Onimaru, Masahiko Izumizaki
Dept. Physiol., Showa Univ. Sch. Med., Japan

1P-332

Effects of feeding-promoting peptides on excitability of the superior
salivatory nucleus neurons
Yoshihiro Mitoh1), Tadasu Sato2), Masako Fujita1), Hiroyuki Ichikawa2),
Motoi Kobashi1), Ryusuke Yoshida1)

Department of Oral Physiology, Okayama University Graduate School of Medicine andDentistry and Pharmaceutical Sciences, Okayama, Japan, 2Division of Oral and
Craniofacial Anatomy, Tohoku University Graduate School of Dentistry, Japan1

1P-333Patch-clamp recordings from CRF+ neuron in the Barrington’s
nucleus using CRF-VenusΔneo mice
Masahiro Kawatani1), Keiichi Itoi2,3), Katsuya Uchida2,3), Kenji Sakimura4)

Department of Neurophysiology, School of Medcine, University of Akita, Japan,
Laboratory of Information Biology, Graduate School of Information Sciences, Tohoku
University, Japan, 3Department of Neuroendocrinology, Graduate School of Medicine,
Tohoku University, Japan, 4Department of Cellular Neurobiology, Brain ResearchInstitute, Niigata University, Japan
1
2

1P-334

Edible sesquiterpene alcohols suppress cytotoxic chemotherapyside effects
Young-Ho Jin, Eunhee Yang

Deartment of Physiolgy, School of Med. Kyung Hee University, Korea

1P-335

Opposite effects of peripheral warming on autonomic nerve activities
in the anesthetized rat
Takehito Kemuriyama1), Yoshiaki Sato2), Hokyoo Lee3), Takuto Nagashima4),
Megumi Tandai-Hiruma2)

1
Department of Nursing, Kiryu University, Japan, 2Department of Physiology, National
Defense Medical College, Japan, 3Department of Engineering, Niigata Institute ofTechnology, Japan, 4SIT Research Laboratories, Shibaura Institute of Technology, Japan

1P-336Is sympathoexcitation by PVN-RVLM neurons augmented in heart
failure?
Eri Hanai, Nao Kumada, Tatsuo Watanabe, Satoshi Koba

Division of Integrative Physiology, Tottori University Faculty of Medicine, Japan

Neuroscience: Autonomic Physiology (1)1P-337

Role of Orexin neurons in the hypothalamus during social defeat
stress in the rat
Ena Yamamoto, Takatoshi Horiuchi, Misaki Ichikawa, Jouji Horiuchi
Department of Biomedical Engineering, Toyo University, Japan

1P-338

Yuhichi Kuda, Mamoru Tanida, Yasutaka Kurata, Toshishige Shibamoto
Department of Physiology 2, Kanazawa Medical University, Japan

Neuroscience: Brain-machine interface
1P-339The efficacy of prosthetic retinal stimulation

Tomomitsu Miyoshi1), Hiroyuki Kanda2), Takeshi Morimoto2),
Takashi Fujikado2)
Department of Integrative Physiology, Graduate School of Medicine, Osaka University,
Japan, 2Department of Applied Visual Science, Graduate School of Medicine, Osaka
University
1

1P-340A possibility of intracortical neural prostheses with carbon-nanotubebased electrodes
Yuki Hayashida, Rira Ohta, Shohei Suga
Grad. Engineering, Osaka University, Japan

Neuroscience: Others (1)1P-341

The neuroprotective effects of Metformin after severe traumatic brain
injury in male rats:
Ali Siahposht-Khachaki1), Ahmadreza Ferdowsi2)

Department of Physiology and Pharmacology, Mazandaran University of Medical
Sciences, Ramsar International Branch, Iran, 2medicine Students, Mazandaran Universityof Medical Sciences, Ramsar International Branch, Iran1

1P-342

In vivo otolith organs: clinical significance of its shape between
normal and Meniere’s disease
Hisaya Tanioka1), Kimitaka Kaga2), Sayaka Tanioka3)

1
Department of Radiology, Tanioka Clinic, Japan, 2National Institute of Sensory Organs,Tokyo Medical Center, 3Tanioka Clinic, Japan

1P-343A newly synthesized adenosine analogue COA-Cl increases
dopamine secretion in mouse brain
Ikuko Tsukamoto1), Mostofa Jamal1), Maki Takata1), Asuka Ito1),
Junsuke Igarashi2), Yasuo Kubota1), Hiroshi Kinoshita1),
Norikazu Sakakibara3), Ryoji Konishi1)

1
Faculty of Medicine, Kagawa University, Japan, 2Morinomiya University of Medical
Sciences, Japan, 3Kagawa School of Pharmaceutical Sciences, Tokushima Bunri
University, Japan

1P-344

Neurotrophic Role of Glucagon-like Peptide-1 Promotes Neuronal
Differentiation via PI3K-AKT Axis
Yun-Ru Yang, Sun Shu-Fang, Yang Jenq-Lin

Institute for Translational Research in Biomedicine,Kaohsiung Chang Gung Memorial
Hospital,Taiwan

Neuroscience: Autonomic Physiology (1)/Neuroscience: Brain-machine interface/ Neuroscience: Others (1)

DAY 2

Effects of anaphylaxis on the gastric autonomic nerve activities inanesthetized rats

1P-345

Cholinergic induction of network oscillations in the slug olfactory
neuron in vitro
Suguru Kobayashi

Kagawa School of Pharmaceutical Sciences, Tokushima Bunri University, Japan

1P-346

Cycle duration-modulated information transfer of olfactory andvomeronasal
sensory neurons in mice
Tomohiro Noguchi, Sadaharu Miyazono, Makoto Kashiwayanagi
Department of Sensory Physiology, Asahikawa Medical University, Japan

1P-347The Neuro-protective Role of Parkin-mediated Mitophagy in Ethambutolinduced Toxic Optic Neuropathy
Jin Hyoung Kim1), Byung Joo Lee1), Jeong Hun Kim1,2)

FARB Laboratory, Clinical Research Institute, Seoul National University Hospital, Korea,
Department of Biomedical Sciences and Ophthalmology, Seoul National University
College of Medicine, Korea

12

1P-348Tregs Protect Dopaminergic Neurons against MPP+ Neurotoxicity via
CD47-SIRPA Interaction
Yan Huang, Zhan Liu, Yuping Peng

Department of Physiology, School of Medicine Nantong University, China

1P-349Pathology-dependent mitochondria-cytoskeleton
amyotrophic lateral sclerosis (ALS)interactioninTomohiro Tanaka1,2), Akiyuki Nishimura3), Okiru Komine4), Koji Yamanaka4),
Motohiro Nishida1,2,3)

National Institute for Physiological Sciences (NIPS), National Institutes of Natural
Sciences, Japan, 2Exploratory Research Center on Life and Living Systems(EXCELLS), National Institutes of Natural Sciences, Japan, 3Graduate School of
Pharmaceutical Sciences, Kyushu University, Japan, 4Research Institute of Environmental
Medicine, Nagoya University, Japan1

1P-350Continuous laryngeal TRPV1 activation modulates swallowing
initiation in anesthetized rats
Midori Yoshihara, Takanori Tsujimura, Makoto Inoue

Division of Dysphagia Rehabilitation, Niigata University Graduate School of Medical
and Dental Sciences, Japan

1P-351Prevention of Dry-Eye Pain by Diquafosol Sodium Administration
Ayano Katagiri1), Koichi Iwata2)

Department of Oral Physiology, Osaka University Graduate School of Dentistry, Japan,
Department of Physiology, Nihon University School of Dentistry1
2

1P-352Analysis of activated cortical area caused by food restriction in mice
Jihao Ma, Sakurako Yanase, Lisa Udagawa, Tomoyuki Kuwaki,
Ikue Kusumoto-Yoshida
Department of Physiology, University of Kagoshima, Japan

1P-353

TLR2-dependent signaling relay of glial-neuronal circuits to regulate
thermoregulation
Saki Murayama, Erkin Kurganov, Seiji Miyata

Department of Applied Biology, Kyoto Institute of Technology, Japan

1P-354

A novel TRPM8 expressing “cold-neuron” in mouse hypothalamus
and medulla
Erkin Kurganov, Kaho Okamoto, Seiji Miyata
Neuroscience: Others (1)Department of Applied Biology, Kyoto Institute of Technology, Japan

1P-355

Sensitivity of voltage-dependent Ca2+ channels in rat AVP neurons toan anthranilic acid derivative
Kaori Sato1,2), Tomohiro Numata1), Yoichi Ueta3), Yasunobu Okada4,5)

1P-356

Behavioral and neural characteristics of recognition of the binary
taste mixture in rats
Tomoki Yamamura, Yoshihisa Katagawa, Toshiaki Yasuo, Takeshi Suwabe,
Noritaka Sako
Dept. Oral Physiol., Asahi Univ. Sch. Dent., Japan

1P-357

An imaging system for 3D detection of nano-vibrations in sensory
epithelium of the inner ear
Fumiaki Nin1), Samuel Choi2), Takeru Ota1), Hiroshi Hibino1)

Department of Molecular Physiology, Niigata University, Japan, 2Department ofElectrical and Electronics Engineering, Niigata University, Japan1

1P-358

Effects of self-motion on the hippocampal CA1 place cell activities in
the freely behaving monkey
Yutaro Hazama, Takashi Asano, Ryoi Tamura

Department of Integrative Neuroscience, Graduate School of Medicine andPharmaceutical Sciences, University of Toyama, Japan

1P-359Massage-like
vocalizations

stroking

stimulationinduces

50-kHzultrasonic

Rie Shimoju1), Miyo Hori2), Hideshi Shibata3), Mieko Kurosawa4,5)

Dept. Physical Ther., Intl. Univ. Health & Welfare, Japan, 2Foundation for Advancementof Intl. Sci., Japan, 3Lab. Vet. Anat., Ins. Agric., Tokyo Univ. Agric & Tech., Japan, 4Center
Med. Sci., Intl. Univ. Health & Welfare, Japan, 5Dept. Pharm. Sci., Intl. Univ. Health &Welfare, Japan1

1P-360Retinal circadian rhythm is entrained by the SCN via corticosterone
secretion from the adrenal gland
Keisuke Ikegami1,2), Mamoru Nagano2), Satoru Masubuchi1),
Yasufumi Shigeyoshi2)

Department of Physiology, School of Medicine, Aichi Medical University, Japan,
Department of Anatomy and Neurobiology, Faculty of Medicine, Kindai University

1
2

1P-361

Exercise capacity and intelligence in adults after betamethasone
given to 4-day-old infant rats
Shunta Maruo, Ayaka Matsuo, Takayoshi Hosono

Department of Biomedical Engineering, Osaka Electro-Communication University,Japan

1P-362

Characteristics of motor and memory functions in cerebral
hypoperfusion model rat by microspheres
Naoyuki Himi1), Naohiko Okabe1), Emi Maruyama Nakamura1),
Hisashi Takahashi2), Norito Hayashi1), Issei Sakamoto1), Tomoshige Koga2),
Osamu Miyamoto1)

1
Department of Physiology 2, Kawasaki Medical School, Japan, 2Department of
Rehabilitation, Kawasaki University of Medical Welfare, Japan

Neuroscience: Others (1)

DAY 2

1
Department of Physiology, Fukuoka University, Japan, 2Japan Society for the Promotionof Science, Japan, 3Department of Physiology, School of Medicine, University ofOccupational and Environmental Health, Japan, 4Department of Physiology and
Systems Bioscience, Kyoto Prefectural University of Medicine, Japan, 5National Institutefor Physiological Science, Japan

1P-363

H2S Attenuates Maternal Cigarette Smoke Exposure-Induced Oxidative Stress in pFRG in Neonatal Rats
Fang Lei, Wen Wang, Yating Fu, Ji Wang, Yu Zheng

Department of Physiology, West China School of Basic Medical Sciences and Forensic
Medicine, Sichuan University, China

1P-364

Maternal Cigarette Smoke Exposure Disturbs Excitatory/Inhibitory
Balance in pFRG of Neonatal RatsFu Yating, Fang Lei, Wang Ji, Zheng Yu

Department of Physiology, West China School of Basic Medical Sciences and Forensic
Medicine, Sichuan University, China

1P-365

Brown adipose tissue is involved in anti-obesity effects of royal jelly
in high fat diet-fed mice
Akira Terao1), Takeshi Yoneshiro2), Ryuji Kaede2), Kazuki Nagaya2),
Julia Aoyama2), Mana Saito2), Yuko Okamatsu-Ogura2), Kazuhiro Kimura2)

1
School of Biological Sciences, Tokai University, 2Laboratory of Biochemistry,
Department of Biomedical Sciences, Graduate School of Veterinary Medicine, Hokkaido
University

1P-366

Effect of LH stimulation on formalin-induced orofacial pain: role oforexin1 receptors in the VTA
Laleh Rezaee Nazifi, Abbas Haghparast

Neuroscience Research Center Shahid Beheshti University of Medical Sciences

1P-367

Ischemic postconditioning induced by opening of mK+ ATP channels
and NMDAR silencing by mPTP opening
Yudai Morisaki1), Ichiro Nakagawa1), Shohei Yokoyama1), Yoichi Ogawa2),
Yasuhiko Saito2), Hiroyuki Nakase1)

1
Department of Neurosurgery, Nara medical university, Japan, 2Department of
Physiology I, Nara medical university, Japan

1P-368

Effect of cannabinoids in prefrontal on decision making mediates via
change in p-CREB and p-GSK3
Zahra Fatahivanani, Abbas Haghparast, Fariba Khodagholi

Neuroscience Research Center, Shahid Beheshti University of Medical Science, Iran

1P-369Low frequency stimulation targeting the subiculum reverses drug
resistance in temporal lobe epilepsy
Fan Fei, Cenglin Xu, Yi Wang, Yao Liu, Ying Wang, Fang Ding, Kai Zhong,Shuang Wang, Zhong Chen
Department of Pharmacology, University of Zhejiang, China

1P-370Utilizing the TRPV1 and TRPM8 channels to facilitate the swallowing

Mohammad Zakir Hossain1), Hiroshi Ando2), Shumpei Unno1), Yuji Masuda3),
Junichi Kitagawa1)

Department of Oral Physiology, Matsumoto Dental University, Japan, 2Department of
Biology, Matsumoto Dental University, Japan, 3Institute for Oral Science, Matsumoto
Dental University, Japan1

1P-371Mating with SFPs deficient males cause the suppression of NaCl
intake in females in Drosophila
Akira Furuyama

Department of Oral Function and Molecular Biology, Ohu University School of Dentistry,Japan

Neuroscience: Others (1)1P-372

Mood stabilizing drugs activate adult neural stem cell-neurogenesis
systemKeita Nakaji1), Natsu Koyama2), Takahiro Fuchigami2), Seiji Hitoshi2)

1
Department of Medical Science, Shiga University of Medical Science, Japan, 2Dept.
Physiology, Shiga Univ. of Medical Science

1P-373

Rimpi Arora, Arjun Singh, Rahul Deshmukh

Dept. of Pharmacology, ISF College of Pharmacy, India

1P-374Chronic EEG recording from rodents using ceramic-guided wire
electrodes
Tomokazu Ohshiro1), Yuchio Yanagawa2), Hajime Mushiake1)

1
Department of Physiology, School of Medicine, Tohoku university, Japan, 2Departmentof Genetic and Behavioral Neuroscience, Graduate School of Medicine, Gunma
University, Japan

1P-375Retinal ON pathways contribute to temporal characteristics of visualmotion processing in mice
Yuko Sugita1,2), Kenichiro Miura2), Takahisa Furukawa1)

Laboratory for Molecular and Developmental Biology, Institute for Protein Research,
Osaka University, Japan, 2Department of Integrative Brain Science, Graduate School of
Medicine, Kyoto University, Japan1

1P-376

Distribution of Smad mRNA and proteins in the rat brain
Takayuki Nakajima

Department of Veterinary Anatomy, Graduate School of Life and Environmental
Sciences, Osaka Prefecture University, Japan

1P-377

Event related potentials in the first-person shooter game with virtual
reality environment
Masashi Arake1,2), Hiroyuki Ohta3), Aki Tsuruhara2), Yuji Morimoto3),
Nariyoshi Shinomiya1)

Department of Integrative Physiology and Bio-Nano Medicine, National Defense
Medical College, Japan, 2Aeromedical Laboratory, Japan Air Self Defense Force, Japan,
Department of Physiology, National Defense Medical College, Japan

1

3

1P-378Changes in reproductive hormones-related genes in hippocampus ofcognitive impaired male rats
Patteera Wititsuwankul, Sukanya Jaroenporn, Taratorn Fainanta,
Suchinda Malaivijitnond

Department of Biology, Faculty of Science, Chulalongkorn University, Thailand

1P-379

Agomelatine protects against on permanent cerebral ischemia modelthrough Nrf2-HO-1 pathway
Wijitra Chumboatong1), Chainarong Tocharus2), Piyarat Govitrapong3),
Jiraporn Tocharus Tocharus1)
1
2
3

1P-380Department of Physiology, Faculty of Medicine, Chiang Mai University, Thailand,
Department of Anatomy, Faculty of Medicine, Chiang Mai University, Thailand,
Chulabhorn Graduate Institute, Thailand

Effects of taurine supplementation with exercise onantioxidant enzymes activities in aging rat brain
Jiraporn Onsri, Rungrudee Srisawat

School of Preclinic, Institute of Science, Suranaree University of Technology, Thailand
Neuroscience: Others (1)

DAY 2

Chebulinic acid negated the development of streptozotocin induced
experimental dementia in rats

1P-381

Effects of quercetin on neuronal activity in the hypothalamic foodintake regulating areas
Naiyana Nontamart, Rungrudee Srisawat

School of Preclinic, Institute of Science, Suranaree University of Technology, Thailand

1P-382Dihydrocapsaicin improves functional recovery after cerebral
ischemia and reperfusion in rat model
Jiraporn Tocharus1), Adchara Janyou2), Chainarong Tocharus2),
Apichart Suksamrarn3)

1
Department of Physiology, Chiang Mai University, Thailand, 2Department of Anatomy,
Chiang Mai University, Thailand, 3Department of Chemistry and Center of Excellence forInnovation in Chemistry, Ramkhamhaeng University

1P-383The Effect of difference of cognitive control levels in SRK model on
EEG frontal theta band
Satoshi Kawashima1), Asako Yoda2)

Graduate School of Literature and Social Sciences, Nihon University, Japan, 2College of
Humanities and Sciences, Nihon University

1

1P-384

Parvalbumin positive neurons in the basolateral amygdala andanxiety-like behavior in OLETF rats
Ryosuke Ochi1), Naoto Fujita1), Natsuki Goto1), Hisao Nishijo2),
Susumu Urakawa1)

Dept. of Musculoskeletal Functional Res. and Regeneration, Grad. Sch. of Biomedicaland Health Sci., Hiroshima Univ., Japan, 2Dept. of System Emotional Sci., Grad. Sch. ofMedical and Pharmaceutical Sci., Univ. of Toyama, Japan1

1P-385

Role of the medulla in the regulation of slow wave sleep

Yoshimasa Koyama, Kazuki Kobayashi, Hayato Iwata, Tatsuya Suzuki,
Kaname Mochizuki, Yoshifumi Arai
Department of Science and Technology, Fukushima University, Japan

1P-386

The Protective Effect of Neferine on Permanent Ischemic Brain Injury
in Rats
Jirakhamoln Sengking1), Jiraporn Tocharus3), Ratchanaporn Chokchaisiri2),
Apichart Suksamrarn4), Chainarong Tocharus1)

Department of Anatomy, Faculty of Medicine, Chiang Mai University, Thailand,
Department of Chemistry, School of Science, University of Phayao, Thailand.,3
Department of Physiology, Faculty of Medicine, Chiang Mai University, Thailand,
4
Department of Chemistry and Center of Excellence for Innovation in Chemistry,
Faculty of Science, Ramkhamhaeng University, Thailand
12

1P-387

Effects of NSAIDs on cerebral glucose metabolism measured by [18F]
FDG uptake in rat brain slices
Tatsuya Asai1,2), Yasuki Narita1), Yasushi Kiyono2), Hidehiko Okazawa2)
1
2

Department of Human and Artificial Intelligence Systems, University of Fukui, Japan,
Biomedical Imaging Research Center, University of Fukui, Japan

Epithelial Transport, Secretion & Absorption: Epithelium (1)1P-388MLCK isoforms regulate intestinal epithelial hyperpermeability under
inflammatory stress
Yu Chen Pai, Tsung-Chun Lee, Chia-Hui Yu

Graduate Institute of Physiology, National Taiwan University College of Medicine,
TaiwanNeuroscience: Others (1)/Epithelial Transport, Secretion & Absorption: Epithelium (1)1P-389

TRPV6 mutations cause neonatal transient hyperparathyroidism

Yoshiro Suzuki1,2), David Chitayat3), Hirotake Sawada4), Gen Nishimura5),
Makoto Tominaga1,2)
Division of Cell Signaling, National Institute for Physiological Sciences, Japan,
Department of Physiological Sciences, SOKENDAI, Japan, 3University of Toronto,
Canada, 4Miyazaki University School of Medicine, Japan, 5Saitama Medical University
Hosptal, Japan1
2

Involvement of EP receptors in the regulation of Short circuit current
by prostaglandins in A6 cells
Sun Hongxin1,2), Marunaka Yoshinori2), Asano Shinji1,2)Dept Mol. Physiol, Coll. Pharm. Sci., Ritsumeikan Univ., Japan, 2Research Organization of
Sci. and Tech., Ritsumeikan Univ.

1

1P-391

Oligomerization of Na+/H+ exchanger isoform 3 (NHE3) and its role in
the transport mechanism
Noriko Ishizuka, Shino Koido, Hisayoshi Hayashi

School of Food and Nutritional Sciences, University of Shizuoka, Japan

1P-392Computer simulation of intracellular HCO3-/CO2 buffering in pancreatic
duct cell

Makoto Yamaguchi1), Martin Steward2), Yoshiro Sohma3), Akiko Yamamoto1),
Hiroshi Ishiguro1)

Department of Human Nutrition, Nagoya University Graduate School of Medicine,Japan, 2School of Medical Sciences, University of Manchester, UK, 3Department ofPharmaceutical Sciences, International University of Health and welfare, Japan1

1P-393

Secretory reflex pathway of Xenin-25 in the rat ileum

Atsukazu Kuwahara1), Yuko Kuwahara2), Ikuo Kato3), Toshio Inui4),
Yoshinori Marunaka1,2,5)

1
Research Unit for Epithelial Physiology, Research Organization of Science andTechnology, Ritsumeikan University, Japan, 2Department of Molecular Cell Physiology,
Graduate School of Medical Science, Kyoto Prefectural University of Medicine,3
Department of Medical Biochemistry, Kobe Pharmaceutical University, 4Saisei Mirai
Clinics, 5Research Institute for Clinical Physiology, Kyoto Industrial Health Association

1P-394

Secretory reflex pathway of SCFA in the rat distal colon

Daiki Harata1), Shinji Asano1,2), Atsukazu Kuwahara2), Toshio Inui3),
Yoshinori Marunaka2,4,5)Dept of Mol Physiol, Coll Pharm Sci, Ritsumeikan Univ, Japan, 2Res Unit for Epithelial
Physiol, Res Org of Sci and Tech, Ritsumeikan Univ, Japan, 3Saisei Mirai Clinics, Japan,
4
Dept Mol Cell Physiol, Grad Sch Med Sci Kyoto Pref Univ Med, Japan, 5Res Inst for Clin
Physiol, Kyoto Ind Health Assoc, Japan1

1P-395Epithelial ion secretion of human bronchial ciliary epithelium
Shigekuni Hosogi1,2), Leonardo Puppulin2), Nobuyo Tamiya4),
Hideo Tanaka3), Koichi Takayama4), Eishi Ashihara1)

Department of Clinical and Translational Physiology. Kyoto Pharmaceutical University,
Japan, 2Department of Molecular Cell Physiology, Graduate School of Medical Sciences,
Kyoto Prefectural University of Medicine, Japan, 3Department of Pathology and Cell
Regulation, Graduate School of Medical Sciences, Kyoto Prefectural University of
Medicine, Japan, 4Department of Respiratory Medicine, Graduate School of Medical
Sciences, Kyoto Prefectural University of Medicine, Japan
1

Epithelial Transport, Secretion & Absorption: Epithelium (1)DAY 2

1P-390Epithelial Transport, Secretion & Absorption: G-I tract (1)1P-396

Zinc finger protein 521 involved in small intestinal function and stem
cell differentiation
Nazuna Morisada, Kotone Miyake, Mamoru Aoto, Noriaki Mitsuda,
Nobutaka Ohkubo

Department of Circulatory Physiology, Graduate School of Medicine, Ehime University,Japan

1P-397

Role of cysteine protease inhibitors in malignancy of oral squamouscell carcinoma
Junko Fujita-Yoshigaki, Megumi Yokoyama, Osamu Katsumata-Kato

Department of Physiology, Nihon University School of Dentistry at Matsudo, Japan

1P-398

Renal impairment disturbs the intestinal microbiota and alters
intestinal motility
Kazuhiro Nishiyama1), Yasu-Taka Azuma2), Hidemitsu Nakajima2),
Tadayoshi Takeuchi2)

Department of Translational Phrmaceutical Sciences Kyushu University, Japan,
Laboratory of Veterinary Pharmacology, Division of Veterinary Science, Osaka
Prefecture University Graduate School of Life and Environmental Science, Japan

1
2

1P-399Down-regulation of PDGFRα+ cells caused colonic dysmotility in
DSS-induced colitis miceWenxie Xu1,2), Chen Lu1), Hongli Lu1), Xu Huang1), Jie Chen2)

Department of anatomy and physiology, Shanghai Jiaotong University , School of
Medicine, China, 2Department of Pediatric Surgery, Xin Hua Hospital, Affiliated to
Shanghai Jiao Tong University School of Medicine, China
1

1P-400

Neurogenic relaxation of Xenin on spontaneous circular muscle
contractions in rat distal colon
Yuko Kuwahara1), Ikuo Kato2), Atsukazu Kuwahara3), Yoshinori Marunaka3,4),
Toshio Inui5)

Department of Molecular Cell Physiology, Kyoto Prefectural University of Medicine,Japan, 2Department of Medical Biochemstry, Kobe Pharmaceutical University, 3Resarch
Unit for Epithelial Physiology, Research Organizasion of Science and Technology,
Ritsumeikan University, 4Reseach Institute for Clinical Physiology, Kyoto Industrial
Health Association, 5Saisei Mirai Clinics
1

1P-401

CRF regulates colonic motility through CRF-PDGFRα+/ICC pathway
Xu Huang, Hong-Li Lu, Han-Yue Fu, Chen Lu, Wen-Xie Xu

Department of Anatomy and Physiology, Shanghai Jiao Tong University School of
Medicine, China

1P-402

Regulation of gastric motility by histamine via interstitial cells of Cajalin the Syrian hamster
Takahiko Shiina1), Kazuhiro Horii1), Satoru Naganuma1), Shohei Yasuda1),
Yasutake Shimizu1,2)

Department of Basic Veterinary Science, Laboratory of Physiology, The United Graduate
School of Veterinary Sciences, Gifu University, Japan, 2Center for Highly Advanced
Integration of Nano and Life Sciences, Gifu University (G-CHAIN)

1

1P-403

Changes of colonic transit in feeding state after abdominal open
surgery in conscious rat
Misaki Okada1), Sazu Taniguchi2), Hiroshi Taniguchi3), Hiroshi Kitakoji4),
Kazunori Itoh5), Kenji Imai6)

Graduate School of Acupuncture and Moxibustion, Meiji University of Integrative

1

Epithelial Transport, Secretion & Absorption: G-I tract (1)Medicine, Japan, 2The Japan School of Acupuncture, Moxibustion and Physiotherapy,
3
Department of Acupuncture and Moxibustion, Tokyo Ariake University of Medical and
Health Sciences, 4Department of Acupuncture and Moxibustion, Takarazuka Universityof Medical and Health Care, 5Department of Acupuncture and Moxibustion, Meiji
University of Integrative Medicine, 6Department of Acupuncture and Moxibustion,
Faculty of Health Science, Teikyo Heisei University

1P-404

Kazuhiro Horii1), Yuka Ehara1), Kiyotada Naitou1), Hiroyuki Nakamori1),
Takahiko Shiina1), Yasutake Shimizu1,2)

Lab Vet Physiol, Unit Grad Sch Vet Sci, Gifu Univ, Japan, 2Center for Highly Advanced
Integration of Nano and Life Sciences, Gifu University (G-CHAIN)

1Epithelial Transport, Secretion & Absorption: Renal Physiology (1)1P-405

Recovery of tight junctional localization and Mg2+ transport of claudin-16 mutant by primaquine
Akira Ikari1), Kana Marunaka1), Toru Kimura2), Hajime Hasegawa3),
Satoshi Endo1), Toshiyuki Matsunaga1)

Laboratory of Biochemistry, Gifu Pharmaceutical University, Japan, 2School of Medicine,
Kyorin University, Japan, 3Saitama Medical Center, Saitama Medical University, Japan1

1P-406

Endocytosis of NKCC2 is impaired in renal tubule in moesin knockout
mice
Kotoku Kawaguchi1), Ryo Hatano2), Shinji Asano1)

1
College of Pharmaceutical Sciences, Ritsumeikan University, Japan, 2Graduate Schoolof Medicine, Chiba University, Japan

1P-407

Quantitative analysis of epithelial transport in proximal tubule withmathematical model
Taiki Nishizuka1), Junichi Taniguchi2), Akinori Noma1), Yukiko Himeno1),
Akira Amano1)

Graduate School of Life Science, Ritsumeikan University, Japan, 2Div. Mol. Pharmcol.
Dept. Pharmcol. Jichi Med. Univ

1

1P-408

Low-Pi diet-induced metabolic acidosis with alkalinuria was reversedin the Pendrin KO mice
Yukiko Yasuoka1), Tomomi Oshima1), Yuichi Sato2), Hiroshi Nonoguchi3),
Noriko Takahashi1), Katsumasa Kawahara1,4)

1
Department of Physiology, Kitasato University, School of Medicine, Japan, 2Departmentof Molecular Diagnostics, Kitasato University, School of Allied Health Sciences, Japan,
3
Division of Internal Medicine, Kitasato University Medical Center, Japan, 4Department
of Health and Nutrition, Sendai Shirayuri Women's College, Japan

1P-409Atorvastatin ameliorates renal injury in high-fat diet-induced obese
rats
Anusorn Lungkaphin, Nattavadee Pengrattanachot, Rada Chengwelling,
La-ongdao Thongnak, Anchalee Pongchaidecha
Department of Physiology, Faculty of Medicine, Chiang Mai University, Thailand

1P-410Protective role of COUP-TFII against cisplatin-induced acute kidney
injurySumiyasu Ishii, Noriyuki Koibuchi

Department of Integrative Physiology, Gunma University Graduate School of Medicine,Japan

Epithelial transport, Secretion & Absorption: G-I tract (1) /Epithelial Transport, Secretion & Absorption: Renal Physiology (1)DAY 2

The mechanism of sexually dimorphic responses of colorectal motility
by noxious stimulation in rats

1P-411

Possible Role of Garlic Oil in Ameliorating Renal Injury after Liver
Ischemia/Reperfusion in Rats
Noha Nooh Lasheen, Wael Alayat, Mohamed Fathy

Associate Professor of Physiology, Physiology Department, Faculty of Medicine, Ain
Shams University, Egypt

1P-412

A novel NEU mutagenesis model rat of chronic kidney disease

Iori Ohmori1), Tomoji Mashimo2), Mamoru Ouchida3), Shinya Toyokuni4)1
Department of special education, Okayama University, Japan, 2The Institute ofExperimental Animal Sciences Department of Medicine, Osaka University, Japan,
3
Department of Molecular Oncology, Graduate School of Medicine, Dentistry, andPharmaceutical Sciences, Okayama University, Japan, 4Department of Pathology andBiological Responses Nagoya University Graduate School of Medicine, Japan

1P-413

Pathogenic role of ERK1/2-mTORC1 axis in adriamycin-induced
glomerulosclerosis
Soo-Jin Kim1), Ranjan Das1), Nhung Thi Nguyen1), Luong Dai Ly1),
Ji-Hee Kim1), Kyu-Hee Hwang1), Dat Da Ly1), Eunha Chang1),
Hyeong Ju Kwon2), Seung-Kuy Cha1), Kyu-Sang Park1)

Department of Physiology, Wonju College of Medicine, Yonsei University, Korea,
Department of Pathology, Wonju College of Medicine, Yonsei University, Korea

1
2

Molecular & Cellular Biology: Channels & Transporters (1)1P-414

Role of TRPV3-ANO1 interaction in keratinocyte wound healing
Yu Yamanoi1,2,3), Yasunori Takayama2,3), Makoto Tominaga2,3)

1
Research Laboratory, Ikedamohando Co., Ltd., Japan, 2Division of Cell Signaling,
National Institute for Physiological Sciences, 3Thermal Biology Group, Exploratory
Research Center on Life and Living Systems(ExCELLS)

1P-415Functional analyses for a Ca2+ binding site of TRPM4 and TRPM5channels
Soichiro Yamaguchi1), Akira Tanimoto2), Shinsuke Iwasa2),
Ken-Ichi Otsuguro2)

Laboratory of Physiology, Department of Basic Veterinary Sciences, Faculty of
Veterinary Medicine, Hokkaido University, Japan, 2Laboratory of Pharmacology,
Department of Basic Veterinary Sciences, Faculty of Veterinary Medicine, Hokkaido
University, Japan1

1P-416

Enhanced activity by NKCC1 and SLC26A6 in cardioplegic arrest of
db/db heart
Minjeong Ji

Department of Physiology, College of Medicine, Gachon University, Lee Gil Ya Cancer
and Diabetes Institute, Korea

1P-417Involvement of thermosensitive TRP channels in temperaturedependent microglia movement
Sandra Derouiche1), Rei Nishimoto1), Kei Eto2), Makoto Tominaga1)

1
Division of Cell signaling, NIPS, Thermal biology group ExCELLS, Japan, 2Division ofHomeostatic development, NIPS, Japan

1P-418Characterization of TRPA1 from disease vector mosquitoes
Tianbang Li1,2,3), Claire Tanaka Saito2,3), Shigeru Saito1,2,3),
Makoto Tominaga1,2,3)

Department of Physiological Sciences, SOKENDAI, Japan, 2Division of Cell signaling,
National Institute for Physiological Sciences, Japan, 3Thermal Biology Group, Exploratory

1

Epithelial Transport, Secretion & Absorption: Renal Physiology (1) /Molecular & Cellular Biology: Channels & Transporters (1)Research Center on Life and Living Systems (ExCELLS), Japan

1P-419Simultaneous intracellular temperature imaging during patch-clamp
recording of TRPV1 activity
Tomoyo Ujisawa1,2), Kunitoshi Uchida3), Kohki Okabe4), Takeharu Nagai5),
Makoto Tominaga1,2)

Exploratory Research Center on Life and Living Systems, National Institutes of Natural
Sciences, Japan, 2National Institute for Physiological Sciences, National Institutes of
Natural Sciences, Japan, 3Department of Physiological Science and Molecular Biology,
Fukuoka Dental College, Japan, 4Graduate School of Pharmaceutical Sciences, The
University of Tokyo, Japan, 5The Institute of Scientific and Industrial Research, Osaka
University, Japan1

A key interaction for modulation of voltage dependence by phosphoinositides in two-pore channel 3
Takushi Shimomura1,2), Yoshihiro Kubo1,2)

Division of Biophysics and Neurobiology, Natl Inst Physiol Sci, Japan, 2Department of
Physiological Sciences, SOKENDAI, Japan1

1P-421

Inhibition of IL-10 transcription by KCa3.1 K+ channel activation inhuman T-cell lymphoma
Susumu Ohya1), Miki Matsui1,2), Junko Kajikuri1), Hiroaki Kito1),
Kyoko Endo1,2), Yuki Hasagawa2), Shin-ya Murate1)

Department of Phramacology, Graduate School of Medical Sciences, Nagoya City
University, Japan, 2Department of Pharmacology, Kyoto Pharmaceutical University

1

1P-422Ion Permeation of Voltage Sensor and its Foundation Structure
Ayako Katagi, Yuichiro Fujiwara

Molecular Physiology & Biophysics, Kagawa University, Faculty of Medicine, Japan

1P-423

Identification of amino acids involved in the 4-isopropylcyclohexanol
action on TRP channels
Hong Dung Thi Nguyen1,2,3), Yasunori Takayama 1,2,3), Makoto Tominaga1,2,3)

Division of Cell Signaling, National Institute for Physiological Sciences, National
Institutes of Natural Sciences, Japan, 2Department of Physiological Sciences, theGraduate University for Advanced Studies, Japan, 3Thermal Biology group, Exploratory
Research Center on Life and Living Systems National Institutes of Natural Sciences,Japan
1

1P-424

TRPV1 and ANO1/TMEM16A interaction in inflammatory pain conditions
Yasunori Takayama, Makoto Tominaga

Thermal Biology Group, Exploratory Research Center on Life and Living Systems(ExCELLS), National Institutes of Natural Sciences, Japan

1P-425

DNA origami scaffolds as templates for Kir3.1/3.4 heterotetramericchannels
Tatsuki Kurokawa1,2), Shigeki Kiyonaka2), Eiji Nakata3), Masayuki Endo4),
Emiko Mori2), Nam Ha Tran2), Chikara Sato6), Hiroshi Sugiyama4,5),
Takashi Morii3), Yasuo Mori2)

Department of Pathophysiology, Faculty of Medicine, Oita University, Japan,
Department of Synthetic Chemistry and Biological Chemistry, Graduate School ofEngineering, Kyoto University, 3Institute of Advanced Energy, Kyoto University, 4Institutefor Integrated Cell-Material Sciences (WPI-iCeMS), Kyoto University, 5Department ofChemistry, Graduate School of Science, Kyoto University, 6Biomedical Research Institute,
National Institute of Advanced Industrial Science and Technology
1
2

Molecular & Cellular Biology: Channels & Transporters (1)DAY 2

1P-4201P-426

A tension-modulated modality of the KcsA channel exclusive for acidactivated state
Masayuki Iwamoto, Shigetoshi Oiki

Department of Molecular Physiology & Biophysics, University of Fukui Faculty of
Medical Sciences, Japan

1P-427

Determinants of Ba2+ sensitivity in zebrafish ROMK channels
Yuriko Takeda1), Fumihito Ono1), Koichi Nakajo1,2)

1Department of Physiology, Osaka Medical College, Japan, 2Division of Integrative
Physiology, Department of Physiology, Jichi Medical University, Japan

1P-428Functional Interaction between TRPM8 and ANO1

Mingyi Dong1,2), Hong Dung Thi Nguyen1,2,3), Tominaga Makoto1,2,3),
Yasunori Takayama1,2,3)

National Institute for Physiological Sciences, Japan, 2Thermal Biology Group,
Exploratory Research Center on Life and Living Systems (ExCELLS), 3Department of
Physiological Sciences, The Graduate University for Advanced Studies (SOKENDAI),Japan
1

1P-429Analysis of dynamic structural rearrangements of Two-Pore Na+
Channel 3 by voltage clamp fluorometryKi-Ichi Hirazawa1,2), Takushi Shimomura1,2), Yoshihiro Kubo1,2)

Division of Biophysics and Neurobiology, National Institute for Physiological Sciences,
Japan, 2Department of Physiological Sciences, The Graduate University for Advanced
Studies, Japan1

1P-430Mechano-gating of Piezo1 mutants identified in patients affected by
Hereditary Xerocytosis
Yohei Yamaguchi1,2), Hélène Guizouarn3), Olivier Soriani3), Akira Takai1),
Peter Kohl2), Rémi Peyronnet2)

1
Department of Physiology, Asahikawa Medical University, Japan, 2Institute forExperimental Cardiovascular Medicine, University Heart Centre Freiburg · Bad
Krozingen, Faculty of Medicine, University of Freiburg, Germany, 3University Côte d’Azur,
CNRS, Inserm, Insitut for Biology Valrose, France.

1P-431

Involvement of TRPA1 channel in FK506-incuced pain sensation
Kunitoshi Uchida1), Tomo Kita1), Kenichi Kato1), Yoshiro Suzuki2),
Makoto Tominaga2,3), Jun Yamazaki1)

Dept of Physiol Sci and Mol Biol, Fukuoka Dental College, Japan, 2Div of Cell Signal,
NIPS, Japan, 3Thermal Biol Group, EXCELLS, Japan1

1P-432

What is the pH-gradient Sensing in the Voltage-Gated H+ Channel?
Yuichiro Fujiwara

Molecular Physiology & Biophysics, Faculty of Medicine / Graduate School of Medicine,
Kagawa University, Japan

1P-433

Withdrawn

1P-434Magnesium ion influx in H9c2 cells with TRPM7 gene silencing
Michiko Tashiro1), Hana Inoue1), Ryo Kobayashi2), Masato Konishi1)

1
Department of Physiology, Tokyo Medical University, Japan , 2Department ofMicrobiology, Tokyo Medical University, Japan

1P-435

The role of TRPM4 in immune responses in keratinocytes and thenovel TRPM4 agonist
Kaori Otsuka Saito1,2), Fumitaka Fujita1,2), Manami Toriyama2),

Molecular & Cellular Biology: Channels & Transporters (1)Ratna Annisa Utami3), Yoshiro Suzuki4,5,6), Fumihiro Okada1,2),
Makoto Tominaga4,5,6), Ken J Ishii7,8)
Fundamental Research Institute, Mandom Corp., Japan, 2Laboratory of Advanced
Cosmetic Science, Graduate School of Pharmaceutical Sciences, Osaka University,
Japan, 3School of Pharmacy, Institut Teknologi Bandung, Indonesia, 4Thermal Biology
Group, Exploratory Research Center on Life and Living Systems National Institutes of
Natural Sciences, Japan, 5Division of Cell Signaling, Okazaki Institute for Integrative
Bioscience, (National Institute for Physiological Sciences), National Institutes of Natural
Sciences; Japan, 6Department of Physiological Sciences, SOKENDAI, (The Graduate
University for Advanced Studies); Japan, 7Laboratory of Vaccine Science, WPI
Immunology Frontier Research Center (iFReC), Osaka University, Japan, 8Laboratory of
Adjuvant Innovation, Center for Vaccine and Adjuvant Research (CVAR), National
Institutes of Biomedical Innovation, Health and Nutrition (NBIOHN), Japan1

Analysis of chondrocytes anion channel activity in vitro model ofosteoarthritis
Kosuke Kumagai1,2), Futoshi Toyoda2), Caroline Staunton3),
Tsutomu Maeda1), Hitoshi Tanigawa1), Noriaki Okumura1),
Mitsuhiko Kubo1), Takahumi Yayama1), Hiroshi Matsuura2), Shinji Imai1),
Richard Barrett-Jolley3)

Department of Orthopaedic Surgery, Shiga University of Medical Science, Japan,
Department of Physiology, Shiga University of Medical Science, Japan, 3Department ofMuscloskeletal Biology, University of Liverpool, United Kingdom
12

1P-437The Ca2+-permeable cation TRPV3 channel: an emerging pivotal
target for itch and skin diseases
Kewei Wang

Department of Pharmacology, School of Pharmacy, Qingdao University, China

1P-438(AP-3)

Cytoplasmic conformational changes of VSP detected by voltage
clamp fluorescence spectroscopy
Akira Kawanabe, Tomoko Yonezawa, Yasushi Okamura
Graduate School of Medicine, Osaka University, Japan

1P-439The regulation of TRPV1 channel gating by intracellular ATP

Takahiro Shimizu, Nobuhiro Yanase, Takuto Fujii, Haruka Sakakibara,
Hideki Sakai
Department of Pharmaceutical Physiology, University of Toyama, Japan

1P-440Recognition of capsaicin via transient receptor potential channel andtransmembrane protein
Yuma Unno1), Kanami Moriya2), Naomi Osakabe1,2), Yoshihisa Hirota1,2)

Systems Engineering and Science, Graduate School of Engineering and Science,
Shibaura Institute of Technology, Japan, 2Department of Bioscience and Engineering,
College of Systems Engineering and Sciences, Shibaura Institute of Technology

1

1P-441

Regulation of TRPM7 channel activity by its kinase domain

Hana Inoue1), Takashi Murayama2), Takuya Kobayashi2), Masato Konishi1)
Department of Physiology, Tokyo Medical University, Japan, 2Department of Cellular
and Molecular Pharmacology, Juntendo University Graduate School of Medicine

1

1P-442Mapping the agonist binding site of the FMRFamide-gated Na+ channel
Yasuo Furukawa, Iori TagashiraLaboratory of Neurobiology, Graduate School of Integrated Arts and Sciences,
Hiroshima University, Japan

Molecular & Cellular Biology: Channels & Transporters (1)DAY 2

1P-436

1P-443

Development of tonotopic differentiation of axon initial segment inavian nucleus magnocellularis
Nargis Akter, Ryota Adachi, Ryota Fukaya, Hiroshi Kuba
Department of Cell Physiology, University of Nagoya, Japan

1P-444A calcium-binding protein S100A10 is a regulator of Maxi-Cl channel
activity
Rafiqul Md. Islam1), Toshiaki Okada1), Abduqodir Toychiev1),
Ravshan Z. Sabirov1,2), Yasunobu Okada1,3)

Div. Cell Signal, National Institute for Physiological Sciences, Japan, 2Lab. Mol. Physiol.,Inst. Bioorg. Chem, Uzb. Acad. Sci., Uzbekistan, 3Dept. Physiol., Kyoto Pref. Univ. Med.,
Japan

1

1P-445

Toward the understanding of hexose specificity of Na+D-glucose
cotransporters SGLT1 and SGLT2
Kazuyo Kamitori1,2), Yuichiro Fujiwara1)

Department of Molecular Physiology and Biophysics, Faculty of Medicine, Kagawa
University, Japan, 2International Institute of Rare Sugar Research and Education,Kagawa
University
1

1P-446The comparison of sensitivity between NaPi-IIa and NaPi-IIb activity
to phosphoinositides
Natsuki Mizutani, Yoshifumi Okochi, Yasushi Okamura
Integrative Physiol, Grad Sch Med, Osaka Univ, Japan

1P-447

An endosome-resident zinc transporter negatively regulates systemicdsRNA spreading in C. elegans
Katsufumi Dejima, Rieko Imae, Yuji Suehiro, Shohei Mitani

Department of Physiology, Tokyo Women's Medical University School of Medicine

1P-448

Evaluation of effects of empagliflozin on mouse ventricular myocytes
Hinako Suzuki1), Takuma Yoshizawa2), Shunsuke Aoki3), Saki Watanabe4),
Yukari Takeda5), Ayako Takeuchi5), Satoshi Matsuoka5)

Fukui Senior High School, 2Fujishima High School, 3Yokohama Science Frontier HighSchool, 4Aomori High School, 5Department of Integrative and Systems Physiology,
Faculty of Medical Sciences, University of Fukui

1

1P-449A united chemotherapy to reverse drug resistance in ovarian cancer
Libo Yu

School of Biomedical Sciences, The Chinesse University of Hong Kong, Hong Kong

1P-450AMP-activated protein kinase dissociates vesicle association ofclathrin heavy chain CHC22
Kazuho Sakamoto1), Stéphane M Camus2), Frances M Brodsky2)

Department of Bio-Informational Pharmacology, University of Shizuoka, Japan,
Division of Biosciences, University College London

12

1P-451

Function analysis of NHE1 using a strategy of cardiomyocyte
differentiation from human iPS cells
Shigeo Wakabayashi, Kiichiro Tomoda, Shunichi Yokoe, Hirofumi Morihara,
Michio Asahi
Department of Pharmacology, Osaka Medical Collage

1P-452Developmental regulation of KCC2 phosphorylation is essential for
GABA signaling and survival
Miho Watanabe1), Jinwei Zhang2), Mohammad Mansuri3), Jingjing Duan3),

Molecular & Cellular Biology: Channels & Transporters (1)Kristopher T Kahle3,4), Atsuo Fukuda1)1
Dept Neurophysiol, Hamamatsu Univ Sch Med, Japan, 2Inst Biomed Clinical Sci, Univ
Exeter Med Sch, UK, 3Dept Neurosurgery, Yale Sch Med, 4Depts of Pediatrics and Cell.
and Mol Physiol; Centers for Mendelian Genomics, Yale Sch Med

1P-453Characterization of transgenic mice overexpressing dominantnegative TRPM7 mutant
Department of Pharmacology, Faculty of Medicine, Fukuoka University, Japan,
Department of Physiology, Faculty of Medicine, Fukuoka University, Japan,
Department of Pharmacology, Faculty of Pharmaceutical Sciences, Tokushima Bunri
University, Japan1
2
3

1P-454Characterizations of the HCO3- transport activities of a choroid
plexus-specific variant of NBC4
Hidekazu Fukuda, Noriko Takahashi

Department of Physiology, Kitasato University School of Medicine, Japan

Molecular & Cellular Biology: Cellular Physiology (1)1P-455Glycative stress influences skeletal muscle growth and cell growthsignaling in mice
Tatsuro Egawa1,2), Yoshitaka Ohno2), Shingo Yokoyama2), Ayumi Goto1,3),
Satoshi Tsuda1), Katsumasa Goto2), Tatsuya Hayashi1)

Graduate School of Human and Environmental Studies, Kyoto University, Japan,
Department of Physiology, Toyohashi SOZO University, Japan, 3Graduate School of
Medical Sciences, Juntendo University, Japan
1
2

1P-456

Intracellular cAMP induces Ca2+ influx in odontoblasts

Maki Kimura1), Asuka Higashikawa1), Sadao Ohyama1,2), Wataru Ofusa1),
Miyuki Shimada1), Hidetaka Kuroda3), Hiroyuki Mochizuki1),
Masayuki Ando1), Kyosuke Kono1), Yoshiyuki Shibukawa1)
Department of Physiology, Tokyo Dental College, Japan, 2Department of Oral Surgery,Tokyo Metropolitan Komagome Hospital, 3Department of Critical Care Medicine andDentistry, Division of Anesthesiology, Kanagawa Dental University

1

1P-457

P2Y6 receptor antagonist MRS2578 induces atypical signaling

Kakeru Shimoda1,2), Caroline Sunggip1), Akiyuki Nishimura3),
Tomohiro Tanaka1), Takuro Numaga-Tomita1,2), Kazuhiro Nishiyama3),
Motohiro Nishida1,2,3)

Division of Cardiocirculatory Signaling, National Institute for Physiological Sciences(Creative Research Group on Cardiocirculatory Dynamism, Exploratory Research Center
on Life and Living Systems (ExCELLS)), National Institutes of Natural Sciences, Japan,
2
Department of Physiological Sciences, School of Life Science, The Graduate University
for Advanced Studies (SOKENDAI), Japan, 3Department of Translational Pharmaceutical
Sciences, Graduate School of Pharmaceutical Sciences, Kyushu University, Japan1

1P-458PDGF signals contribute to proliferation and migration of humanprostate cancer cell
Md Junayed Nayeem, Aya Yamamura, Rie Takahashi, Hisaki Hayashi,
Motohiko Sato
Department of Physiology, Aichi Medical University, Japan

1P-459Single-cell imaging analysis of inflammatory JNK signaling
Taichiro Tomida1), Kimitaka Yamaguchi1), Masanori Ito1),
Yoshinori Mikami1), Daisuke Ohshima1), Shingo Murakami2),

Molecular & Cellular Biology: Channels & Transporters (1)/Molecular & Cellular Biology: Cellular Physiology (1)DAY 2

Tomo Kita1), Hideaki Tagashira1), Tomohiro Numata2), Satomi Kita1,3),
Takahiro Iwamoto1)

Satomi Adachi-Akahane1)
Department of Physiology, Faculty of Medicine, School of Medicine, Toho University,
Japan, 2Department of EECE, Faculty of Science and Engineering, Chuo University

1

1P-460

LMHFV promotes BMSCs to Differentiate into osteoblast via a Novel
lincRNA-7140 in osteoporosis rat
Liang Li1), Chengjian Cao1), Xiaoqin Yu1), Huiming Li1), Xiaojing Liu2),
Wenchao Wu2), Xueling He1)

Institute of Biomedical Engineering, School of Preclinical and Forensic Medicine, West
China Center of Medical Sciences, Sichuan University, China, 2Laboratory of
Cardiovascular Diseases, Regenerative Medicine Research Center, West China Hospital,
Sichuan University, China

1

1P-461

Effect of hydrogen sulfide and L-cysteine on the principal cells of rat
cortical collecting ducts
You Komagiri

Department of Physiology, School of Medicine, Iwate Medical University, Japan

1P-462

Voltage-dependent Ionic Channels in Human Cementoblast

Satomi Kamata1), Asuka Higashikawa2), Maki Kimura2), Sadao Oyama2),
Yoshiyuki Shibukawa2), Shuichiro Yamashita1)
Department of Removable Partial Prosthodont,Tokyo Dent Coll, Japan, 2Department of
Physiology, Tokyo Dent Coll

1

1P-463Insulin Regulates Adrenal Steroidogenesis by Stabilizing SF-1 Activity
Dong Joo Yang1,2), Ann Wambui Kinyua2), Ji Su Sun1), Seul Ki Kim1),
Yun-Hee Choi1), Dong Min Shin1), Ki Woo Kim1)

1
Department of Oral Biology, Yonsei University, Korea, 2Departments of Pharmacology
and Global Medical Science, Wonju College of Medicine, Yonsei University

1P-464

The 2nd Residue of GPCR Helix 8 May Control Transient and SpecificInteraction with its G Protein
Takaaki Sato1), Hiroyoshi Matsumura2)

Biomed Res Inst, Natl. Inst. Adv. Indust. Sci. & Technol., Japan, 2Dept Biotech, Coll Life
Sci, Ritsumeikan Univ, Japan1

1P-465

The role for O-linked N-acetylglucosamine cycling in macrophageToll-like receptor signaling
Ken Shirato1), Junetsu Ogasawara2), Takuya Sakurai1), Kazuhiko Imaizumi3),
Hideki Ohno4), Takako Kizaki1)

Kyorin University School of Medicine, Japan, 2School of Medicine, Asahikawa Medical
University, Japan, 3Faculty of Human Sciences, Waseda University, Japan, 4Social Medical
Corporation, the Yamatokai Foundation, Japan1

1P-466

Hypotonic Stress Induces ATP Release via Volume-regulated Anion
Channels in Breast Cell Lines
Kishio Furuya1,2), Yuko Takahashi1), Masahiro Sokabe1)
12

1P-467

Mechanobiology Lobo, Nagoya University Graduate School of Medicine, Japan,
Research Center of Health, Physical Fitness and Sports, Nagoya University, Japan

Estrogen deficiency compromised the β2AR-Gs/Gi: implications forarrhythmia and cardiac injury
Yu Zhang1), Hongjian Hou1), Zhiwei Zhao2), Jeremiah Ong’achwa Machuki1),
Lin Zhang1), Yan Zhang1), Lu Fu1), Jinxia Wu1), Yuyu Liu2), Sian E. Harding3),
Hong Sun1)
1

Physiology Department, Xuzhou Medical University,China, 2Institute of Cardiovascular
Molecular & Cellular Biology: Cellular Physiology (1)Disease Research, Xuzhou Medical University, China, 3Myocardial Function Section,
National Heart and Lung Institute, Imperial College London

1P-468Inhibition of HSC activation by caffeine is elicited by antagonizing
adenosine receptor-Akt1 pathway
Momoka Yamaguchi, Tomoya Morishita, Shin-ya Saito, Tomohisa Ishikawa
Department of Pharmacology, University of Shizuoka, Japan

Phosphorylation analysis in renal arterioles by advanced phos-tag
SDS-PAGE method
Kosuke Takeya

Department of Veterinaly Medicine, Okayama University of Science, Japan

1P-470IL-6 promotes CDK5-induced STAT3/androgen receptor activation in
prostate cancer cells
Wan-Chen Yu1), Pei-Chi Li1), Fu-Ning Hsu1), Chieh-Lin Jerry Teng2),
Hsin-Yi Wang3), Mei-Chih Chen4,5), Ho Lin1)

Department of Life Sciences, National Chung Hsing University, Taiwan, 2Department ofDivision of Hematology/Medical Oncology, Taichung Veterans General Hospital,
Taiwan, 3Department of Nuclear Medicine, Taichung Veterans General Hospital, Taiwan,
4
Medical Research Center for Exosomes and Mitochondria Related Diseases, China
Medical University Hospital, Taiwan, 5Department of Nursing, Asia University, Taiwan
1

1P-471

Acute exposure to PRMT1 inhibitor can regulate contraction in
isolated mouse ventricular myocytes
Xue An1), Hyun Ji Kim1), Jung Hoon Pyun2), Jong Sun Kang2), Hana Cho1)

Department of Physiology, Single Cell Network Resarch Center, Sungkyunkwan
University School of Medicine, Korea, 2Department of Molecular Cell Biology, Single Cell
Network Resarch Center, Sungkyunkwan University School of Medicine, Korea
1

1P-472

Conditional deletion of PRMT1 in adult brain reveals its neuronal cell
type-specific roles
Yoo Bin Kim1), Hyun Kyung So2), Jong Sun Kang2), Hana Cho1)

Department of Physiology, Single Cell Network Resarch Center, Sungkyunkwan
University School of Medicine, Korea, 2Department of Molecular Cell Biology, Single Cell
Network Resarch Center, Sungkyunkwan University School of Medicine, Korea
1

1P-473

Procathepsin B without mannose-6-phosphaste is released fromsecretory granules
Osamu Katsumata-Kato, Megumi Yokoyama, Junko Fujita-Yoshigaki

Department of Physiology, Nihon University School of Dentistry at Matsudo, Japan

1P-474

Pathophysiological roles of an actin-binding protein ezrin in thekidneyShinji Asano1), Kotoku Kawaguchi1), Tomonori Okazaki1), Ryo Hatano2)

College of Pharmacy, Ritsumeikan University, Japan, 2Chiba University Graduate
School of Medicine

1

1P-475The efflux characteristics of mitochondrial calcium

Jeong Hoon Lee1), DuongDuc Pham1), ChaeHun Leem1,2)
Department Physiology, University of Ulsan, Korea, 2ASAN medical center, Korea

1

1P-476

Role of mito-KATP channel in Formation of the De-energized
Mitochondrial Membrane Potential
ChaeHun Leem1,2), JeongHoon Lee1), QuynhMai Ho1), DuongDuc Pham1)

1
Department of Physiology University of Ulsan College of Medicine, Korea, 2Asan
Medical Center, Korea

Molecular & Cellular Biology: Cellular Physiology (1)DAY 2

1P-469

1P-477

Multistep adaptation of nuclear transport system depending onvarying heat stress
Yutaka Ogawa, Naoko Imamoto

Cellular Dynamics Laboratory, RIKEN Cluster for Pioneering Research, Japan

1P-478

Physiological functions of Hikeshi, a nuclear import carrier ofmolecular chaperone HSP70
Shingo Kose, Ai Watanabe, Naoko Imamoto

Cellular Dynamics Laboratory, RIKEN Cluster for Pioneering Research, Japan

1P-479Palmitate induces ER Ca2+ depletion and defective lysosomal Ca2+
release in insulin-secreting cells
Luong Dai Ly1,2), Dat Da Ly1,2), Nhung Thi Nguyen1,2), Soo-Jin Kim1,2),
Seung-Kuy Cha1,2), Myungsik Lee3), Kyu-Sang Park1,2)

Department of Physiology, Wonju College of Medicine, Yonsei University, Korea,
Mitohormesis Research Center, Wonju College of Medicine, Yonsei University,
Department of Internal Medicine, College of Medicine, Yonsei University, Korea

12
3

1P-480

Direct Fyn-paxillin binding controls migration of coronary arterysmooth muscle cells
Ying Zhang, Min Zhang, Bochao Lyu, Hiroko Kishi, Tomoka Morita,
Qian Lu, Nan Li, Sei Kobayashi
Dept Mol Cell Physiol, Yamaguchi Univ, Grad Sch Med, Japan

1P-481

Fascia related muscle contracture
Akihiro Kaizu, Yoshiyuki Tsuboi

Department of Physiology, Nihon University School of Dentistry, Japan

1P-482

Inhibitory effects of chloride intracellular channel protein 2 on distantmetastasis of tumor cells
Akihiro Umakoshi1), Saya Ozaki2), Yutaro Sumida1), Shota Ohsumi1),
Erika Hayase1), Yoshitomo Ueno3), Yasutsugu Takada3), Takeharu Kunieda2),
Hajime Yano1), Junya Tanaka1)

Department of Molecular and Cellular Physiology, Graduate School of Medicine,
Ehime University, Japan, 2Department of Neurosurgery, Graduate School of Medicine,
Ehime University, Japan, 3Department of Hepato Gallblad Pancreatic, Graduate Schoolof Medicine, Ehime University, Japan1

1P-483

Gelatin alters the TGF-beta signaling for RANKL induced osteo­
clastogenesis
Yingming Liou, Wei-Ting Lin

Department of Life Sciences, National Chung Hsing University, Taiwan

1P-484

Evaluation of cell damage during cold-stress and re-warming
Daisuke Kobayashi, Keisuke Yoshida, Shingo Tsuji, Tomoki Nagae,
Akihiro Hazama

Department of Cellular and Integrative Physiology, Fukushima Medical University,
Japan

1P-485

The role of BAG3 on the heat-induced cell death in human cancer
cells
Yoshiaki Tabuchi1,2), Tatsuya Yunoki3), Yukihiro Furusawa4),
Tetsushi Hirano1), Atsushi Hayashi3)Life Science Research Center, University of Toyama, Japan, 2Graduate School of
Innovative Life Science, University of Toyama, Japan, 3Department of Ophthalmology,
Graduate School of Medicine and Pharmaceutical Sciences, University of Toyama,
1

Molecular & Cellular Biology: Cellular Physiology (1)Japan, 4Department of Liberal Arts and Sciences, Toyama Prefectural University, Japan

1P-486

Lysosomal Proton Sponge Effect by a Cationic Gold NanorodDoxorubicin in Cancer Cells
Dongun Lee1), Jun-Young Park1), Song Kwon1), Jun Young Park1),
Dongwoo Khang1,2), Jeong Hee Hong1,2)

1
Lee Gil Ya Cancer and Diabetes Institute, Gachon University, Korea, 2Department of
Physiology, Gachon University, South Korea

Periodontitis elicits salivary gland atrophy via plasma TNF-α andinfiltration of B-cells
Takemi Shikayama1,3), Misa Sago-Ito2), Suzuro Hitomi1), Izumi Ujihara1),
Mako Naniwa1), Michihiko Usui3), Keisuke Nakashima3), Kentaro Ono1)

Division of Physiology, Kyushu Dental University, Japan, 2Division of Orofacial Functions
Ortho, Kyushu Dental University, 3Division of Periodontol, Kyushu Dental University

1

1P-488N-terminal region of apoptosis-inducing factor stabilizes formation of
charge transfer complex
Tetsuo Yamashita1), Takeshi Hashimoto1), Junsuke Igarashi1,2),
Hiroaki Kosaka1), Katsuya Hirano1)

1
Dept. of Cardiovasc. Physiol., Kagawa Univ., Japan, 2Dept. of Med. Engineer., Morinomiya
Univ. of Med. Sci., Japan

1P-490Loss of GPx4 in vascular endothelial cells induces accumulation oflipid peroxide and cell death
Toshinori Yasuzawa1), Yoshie Sumikawa2), Osamu Sakai3),
Shigeru Ueshima1,2,4)

Department of Food Science and Nutrition, Faculty of Agriculture, Kindai University,
Japan, 2Major in Applied Biological Chemistry, Graduated school of Agriculture, Kindai
University, 3Senju Laboratory, Senju Pharmaceutical Co., Ltd., 4Antiaging Center, Kindai
University
1

1P-491

Synergistic inhibition of Dinaciclib and Paclitaxel on breast cancer
cell growth
Yu-Hsuan Li1), Hsin-Shun Tseng2), Mei-Chih Chen3,4), Ho Lin1)

1
Department of Life Sciences, National Chung Hsing University, Taiwan, 2Comprehensive
Breast Cancer Center, Changhua Christian Hospital, Taiwan, 3Medical Research Center
for Exosomes and Mitochondria Related Diseases, China Medical University Hospital,
Taiwan, 4Department of Nursing, Asia University, Taiwan

1P-492Bitter tastant and bacterial metabolite modulate glucagon-like peptide-1 secretion
Kazuki Harada1), Hidekazu Sakaguchi2), Shoko Sada1), Takashi Tsuboi1,2)

Department of Life Sciences, Graduate School of Arts and Sciences, The University ofTokyo, Japan, 2Department of Biological Sciences, Graduate School of Science, The
University of Tokyo

1

1P-493

Sequential phosphoinositide conversion is required for TGFβ–
induced receptor endocytosis in ECs
Sho Aki1), Kazuaki Yoshioka1), Noriko Takuwa2), Yoh Takuwa1)
1
2

1P-494

Department of Physiology Kanazawa University School of Medicine, Japan,
Department of Health and Medical Sciences, Ishikawa Prefectural Nursing University

The roles of p11 for the localization and heteromeric channel
formation of TASK1 and TASK3 isoforms
Hidetada Matsuoka, Keita Harada, Masumi Inoue

Department of Cell and Systems Physiology, University of UOEH, Japan
Molecular & Cellular Biology: Cellular Physiology (1)DAY 2

1P-487

1P-495

Astrocytic spontaneous hormone exocytosis modulated by spontaneous cytosolic Ca2+ increase
Mai Takizawa, Kazuki Harada, Takashi Tsuboi

Department of Life Sciences, Graduate School of Arts and Sciences, The University ofTokyo, Japan

1P-496

Molecular mechanisms of deoxycholic acid induced glucagon-like
peptide-1 secretion
Maoko Takashima, Kazuki Harada, Taichi Kamiya, Takashi Tsuboi

Department of Life Sciences, Graduate School of Arts and Sciences, The University ofTokyo, Japan

1P-497

Effect of temperature on raft-dependent endocytosis during activationof T cells by concanavalin A
Masahiro Takagi, Neha Sharma, Naofumi Shimokawa

School of Materials Science, Japan Advanced Institute of Science and Technology,Japan

1P-498

Electrophysiological evidence for increased thrombopoiesis in thebone marrow in CRF rat model
Itsuro Kazama1,2)
1

1P-499Miyagi University, Japan, 2Tohoku University, JapanThe outer BRB in diabetic retina is regulated by interaction between
microglia and RPE cells
Jeong Hun Kim1,2,3), Jin Hyoung Kim3), Dong Hyun Jo3), Jang-Hyuk Yun1),
Chung-Hyun Cho1)

Department of Biomedical Sciences, Seoul National University College of Medicine,
Korea, 2Department of Ophthalmology, Seoul National University College of Medicine,
Korea, 3FARB Laboratory, Clinical Research Institute, Seoul National University Hospital1

1P-500

Expression of Tyrosine Hydroxylase in CD4+ T Cells Alleviates
Collagen-Induced Arthritis
Xiao-Qin Wang, Yan Liu, Yi-Hua Qiu

Department of Physiology, School of Medicine, Nantong University, China

1P-501

Effects of 405 nm light by using light emitting diods on cultured HeLa
cells
Toshitaka Ikehara1,2), Mutsumi Nakahashi3), Takahiro Emoto5),
Masatake Akutagawa5), Koichiro Tsuchiya4), Akira Takahashi6),
Yohsuke Kinouchi 5)

Department of Human Welfare, Faculty of Health and Welfare, Tokushima Bunri
University, Japan, 2Division of Biomolecular and Structural Biology, Institute for Health
Sciences, Tokushima bunri University, 3Tokushima Agriculture, Forestiy and Fisheries
Technology Support Center , 4Department of Medical Pharmacology, Department ofInstitute of Biomedical Sciences,Tokushima University, 5Graduate School of Technology,
Industrial and Social Sciences, Tokushima University, 6Department of Preventive
Environment and Nutrition, Institute of Biomedical Sciences,Tokushima University
1

1P-502

Inhibitory effect of Corylifol C on RANKL-induced osteoclast differentiation and bone resorption
Jung Yun Kang, Dong Min Shin

Department of Oral Biology, Yonsei University College of Dentistry, Korea

1P-503

Sestrin 2 regulates osteoclast differentiation through interaction with
p62 and TRAF6
Molecular & Cellular Biology: Cellular Physiology (1)Namju Kang, Sue Young Oh, Dong Min Shin
Department of Oral Biology, BK21 PLUS project, Yonsei University College of Dentistry,
Korea

1P-504

A novel screening system to predict injured organs using cell-free
DNA in serum
Wataru Miyazaki, Hiroyuki Yajima, Michifumi Kokubo, Noriyuki Koibuchi

1P-505The stress-induced stress tolerance acquisition in ciliated protozoan
Paramecium caudatum
Mikihiko Arikawa1), Yasutaka Chikuda2), Tatsuomi Matsuoka1)

Department of Biological Sciences, Faculty of Science and Technology, Kochi
University, Japan, 2Department of Physiology, Kochi Medical School, Japan1

1P-506

Calcium-dependent regulation of cortical actin filaments in mouseeggs
Shunta Arakawa, Takashi Yoshida, Hideki Shirakawa

Department of Engineering Science, The University of Electro-Communications, Japan

1P-507

Target-gene disruption by CRISPR/xCas9 system in Drosophilamelanogaster
Xuyang Ni, Gongyin Ye, Jia Huang

Institute of Insect Sciences, Zhejiang University, China

1P-508

Electrophysiological properties of inwardly rectifying K+ channel inglioblastoma stem-like cells
Mikio Hayashi1), Ryoichi Iwata2), Naaz Andharia1), Kohei Ofune2),
Kunikazu Yoshimura2), Masahiro Nonaka2), Akio Asai2), Hiroko Matsuda1)

1
Department of Physiology, Kansai Medical University, Japan, 2Department of
Neurosurgery, Kansai Medical University, Japan

1P-509Downregulating CXCR4 by miR-139 to restrain breast cancer stem
cell-like phenotypes
Chun-Wen Cheng1,2), Po-Ming Chen1), Hui-Ping Shiau1), Yi-Hsien Hsieh1),
Jyh-Cherng Yu3), Chen-Yang Shen4)

Institute of Biochemistry, Microbiology and Immunology, Chung Shan Medical
University, Taiwan, 2Clinical Laboratory, Chung Shan Medical University Hospital,
Taiwan, 3National Defense Medical College, Department of Surgery, Tri-Service General
Hospital, Taiwan, 4Institute of Biomedical Sciences, Academia Sinica, Taiwan

1

1P-510CHIP-mediated ubiquitination of Gal1 predicts prognosis of colorectal
cancer
Wei min Wang1,2,3)

1
Department of oncology, Yangzhou University, China, 2 Department of Oncology,
Yixing Hospital Affiliated to Medical College of Yangzhou University, China ,3
Department of Physiology, School of Medicine, Showa University, Japan

1P-511

CD105 maintains the thermogenic program of beige adipocyte
Ryoko Higa1), Toshikatsu Hanada2), Reiko Hanada1)
1
2

1P-512

Department of Neurophysiology, Oita University Faculty of Medicine, Japan,
Department of Cell Biology, Oita University Faculty of Medicine, Japan

Leucine and Caffeine induce mitochondrial biogenesis and down­
regulation of miRNAs in C2C12 myotubes
Claudia Perez Lopez1), Tsubasa Shibaguchi2), Kazumi Masuda1)
Molecular & Cellular Biology: Cellular Physiology (1)DAY 2

Department of Integrative Physiology, Graduate School of Medicine, Gunma University,JapanDepartment of Exercise Physiology, Faculty of Human Sciences, University ofKanazawa, Japan, 2Institute of Liberal Arts and Science, Kanazawa University, Japan1

1P-513

Effects of supplementation of fatty acids on viability of B16F10 andneural stem cells
Naomi Ohuchi, Masanori Katakura

Department of Pharmaceutical Sciences, University of josai, Japan

1P-514

STAT6 promotes myoblast differentiation and fusion

Mitsutoshi Kurosaka, Yuji Ogura, Kazuhisa Koda, Toshiya Funabashi
Department of Physiology, St. Marianna University School of Medicine, Japan

1P-515

Analysis of Molecular and Cellular Roles of the GON domain in ERto-Golgi transport
Swako Yoshina1), Shohei Mitani1,2)
1

Department of Physiology, TWMU, Japan, 2TIIMS, TWMU, Japan

Adaptation, Environment & Evolution (1)1P-517

Relationships between exploration and anxiety in male Formosanwood mice (Apodemus semotus)
Shu-Chuan Yang1), Hsien-Yong Lai2), Kun-Ruey Shieh3)

Holistic Education Center, Tzu Chi University of Science and Technology, Taiwan,
Division of Anesthesiology, Mennonite Christian Hospital, Taiwan, 3Department of
Physiology, Tzu Chi University, Taiwan
12

1P-518

Exploratory behaviors related to central dopaminergic activities inmale Formosan wood mice
Kun-Ruey Shieh1), Shu-Chuan Yang2), Hsien-Yong Lai3)

1
Department of Physiology, Tzu Chi University, Taiwan, 2Holistic Education Center, Tzu
Chi University of Science and Technology, Taiwan, 3Division of Anesthesiology,
Mennonite Christian Hospital, Taiwan

1P-519Characterization of splicing variants of frog TRPA1 revealed divergence in their thermal property
Claire Saito1,2), Shigeru Saito1,2,3), Makoto Tominaga1,2,3)

Thermal Biology Group, Exploratory Research Center on Life and Living Systems(ExCELLS), Japan, 2Division of Cell Signaling, National Institute for Physiological Sciences,
Japan, 3Department of Physiological Sciences, SOKENDAI (The Graduate University for
Advanced Studies), Japan1

1P-520(AP-7)

Fos expression in the hypothalamic nuclei after changes fromhypergravity to normal gravity in mice
Yoichi Ueta1), Mitsuhiro Yoshimura1), Satomi Sonoda1), Takashi Maruyama1),
Chikara Abe2), Hironobu Morita2)

Department of Physiology, School of Medicine, University of Occupational andEnvironmental Health, Japan, 2Department of Physiology, Gifu University Graduate
School of Medicine, Japan1

1P-522

Impact of long-term stay in micro-gravity on vestibular function
Hironobu Morita1), Chikara Abe1), Kunihiko Tanaka2)

1
Department of Physiology, Gifu University Graduate School of Medicine, Japan, 2Gifu
University of Medical Sciences

1P-523

Effect of RBM3 on Glycolysis and Apoptosis in the Liver After AcuteCold Exposure
Shize Li, Hongzhao Shi, Ruizhi Yao, Shuai Lian, Peng Liu, Yang Liu,

Molecular & Cellular Biology: Cellular Physiology (1)/Adaptation, Environment & Evolution (1)Yuying Yang, Huanmin Yang, Shize Li, Hongzhao Shi
College of Animal Science and Veterinary Medicine, Heilongjiang Bayi Agricultural
University, China

1P-524

Different adaptation of Chinese expeditioners during prolonged
Antarctic and sub-Antarctic residence
Chengli Xu1, Shiying Liu1), Nan Chen1), Quan Wu2), Hao Li3), Tao Zhang4)

Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences, China,
Department of General Surgery, Beijing Jishuitan Hospital, China, 3Beijing Friendship
Hospital, China, 4Beijing Tongren Hospital, China
1

1P-525

Circadian Rhythm and Sleep during Prolonged Antarctic Residence
at Chinese Zhongshan Station
Yanlei Xiong1), Chengli Xu1), Nan Chen1), Quan Wu2), Guang Chen3),
Dandan Chen3)

Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences, China ,Department of General Surgery, Beijing Jishuitan Hospital, China , 3Beijing Institute ofTechnology, China
1
2

1P-526The sleep parameter and autonomic nervous response in menopausal
womenMichiko Tanaka1), Mou Nagasaka1), Chiyomi Egami2), Miyuki Matsuyama2),
Kiyoka Yamashita2), Yukiko Ogata2), Aki Nozue3), Yoshikazu Sakakibara4)

1
School of Nursing, Miyazaki Prefectural Nursing University, Japan, 2Fukuoka Prefectural
University , 3Miyazaki University, 4Kanazawa Institute of Technology

1P-527

Time since injury and thermoregulatory responses in hyperthermic
person with spinal cord injury
Yoshi-Ichiro Kamijo1,3), Manabu Shibasaki2), Tokio Kinoshita3),
Takashi Moriki3), Yasunori Umemoto1), Ken Kouda1), Fumihiro Tajima1,3)

Department of Rehabilitation Medicine, Wakayama Medical University, Japan,
Department of Health Sciences, Nara Women’s University, Japan , 3Medical Center for
Health Promotion and Sport Science, Wakayama Medical University, Japan
1
2

1P-528Neural network during cognitive tasks during whole body heat stress
Manabu Shibasaki, Hiroki Nakata

Department of Health Sciences, Nara Women's University, Japan

1P-529A study of ultradian rhythm expression with a mathematical model
Hiroko Sawai, Tetsuo Kurahashi
Toyota Central R&D Labs., Inc., Japan

1P-530Ultradian Calcium Rhythms in the PVN and SPZ in the Hypothalamus
Ryosuke Enoki1), Yu-Er Wu2), Yoshiaki Oda3), Zhi-Li Huang2),
Ken-Ichi Honma4), Sato Honma4)

Laboratory of Molecular and Cellular Biophysics, Research Institute for Electronic
Science, Hokkaido University, Japan, 2State Key Laboratory of Medical Neurobiology,
School of Basic Medical Sciences, Fudan University, China, 3Department of Oral ChronoPhysiology, Graduate School of Biomedical Sciences, Nagasaki University, Japan,
4
Research and Education Center for Brain Science, Hokkaido University Graduate
School of Medicine, Japan1

1P-531

Thermosensors and neural circuit regulating temperature-dependent
negative masking behavior in mice
Wataru Ota1,2), Yusuke Nakane1,2), Makiko Kashio4), Yoshiro Suzuki5,6),
Kazuhiro Nakamura7), Yasuo Mori8), Makoto Tominaga5,6),
Takashi Yoshimura1,2,3,9)Institute of Transformative Bio-Molecules (WPI-ITbM), Nagoya University, Japan,

1

Adaptation, Environment & Evolution (1)

DAY 2

2

Laboratory of Animal Integrative Physiology, Graduate School of Bioagricultural
Sciences, Nagoya University, Japan, 3Avian Bioscience Research Center, Graduate
School of Bioagricultural Sciences, Nagoya University, Japan, 4Department of
Physiology, Aichi Medical University, Japan, 5Division of Cell Signaling, National Institutefor Physiological Sciences, National Institutes of Natural Sciences, Japan, 6Thermal
Biology Group, Exploratory Research Center on Life and Living Systems, National
Institutes of Natural Sciences, Japan, 7Department of Integrative Physiology, Nagoya
University Graduate School of Medicine, Japan, 8Department of Synthetic Chemistry
and Biological Chemistry, Graduate School of Engineering, Kyoto University, Japan,
9
Division of Seasonal Biology, National Institute for Basic Biology, National Institutes of
Natural Sciences, Japan2

1P-532

Real time recording of clock gene expression in multiple tissues offreely moving mice
Toshiyuki Hamada, Kazuko Hamada

Department of Pharmaceutical Sciences, International University of Health and Welfare,Japan

1P-533The evaluation of activity and body temperature fluctuation in animalmodel of shift work
Hiroaki Fujihara, Nobuhiro Fujiki

Department of Ergonomics, Institute of Industrial Ecological Science, University ofOccupational and Environmental Health, Japan

1P-534

Optical imaging of circadian calcium rhythm in a solitary supra­chiasmatic neuron
Yoshihiro Hirata1), Ryosuke Enoki1,2), Kaori Kuribayashi-Shigetomi4),
Yoshiaki Oda5), Sato Honma3,5), Ken-Ichi Honma3,5)

Photic Bioimaging Section, Hokkaido University Graduate School of Medicine,
Precursory Research for Embryonic Science and Technology (PRESTO), Japan Scienceand Technology Agency (JST), 3Department of Chronomedcine,Hokkaido University
Graduate School of Medicine, 4Nitobe School, Institute for the Advancement of Higher
Education, Hokkaido University, 5Research and Education Center for Brain Science,
Hokkaido University
1
2

1P-535Chemical and thermal sensitivity of axolotl TRPA1

Mai Oda1,2), Hajime Ogino1), Yoshihiro Kubo3), Koji Shibasaki2),
Osamu Saitoh1)

Department of Animal Bio-Science, Faculty of Bio-Science, Nagahama Institute of BioScience and Technology, 2Department of Molecular and Cellular Neurobiology, Gunma
University Graduate School of Medicine, 3Division of Biophysics and Neurobiology,
Department of Molecular & Cellular Physiology, National Institute for Physiological
Sciences
1

1P-536Innate and acquired cold tolerant properties in hibernating Syrian
hamsters (Mesocricetus auratus)
Hiroki Shimaoka1), Yuuma Yoshida1), Manami Kurata1), Yuuki Horii1),
Hiroki Sakai2), Takahiko Shiina1), Yasutake Shimizu1,3)

Department of Basic Veterinary Science, Laboratory of Physiology, The United Graduate
School of Veterinary Sciences, Gifu University, Japan, 2Department of Pathogenetic
Veterinary Science, Laboratory of Veterinary Pathology, The United Graduate School of
Veterinary Sciences, Gifu University, Japan, 3Center for Highly Advanced Integration of
Nano and Life Sciences (G-CHAIN), Gifu University, Japan1

1P-537

Effect of blue light blocking glass on melatonin secretion and sleep
quality in humans
Sayo Oishi1), Maki Sato2), Chihiro Kodama2), Yoko Inukai2), Mika Kamiya2),
Naoki Nishimura2), Satoshi Iwase2)
Adaptation, Environment & Evolution (1)1Aichi Medical University School of Medicine, Japan, 2Department of Physiology, Aichi
Medical University, Japan

1P-538Cell autonomous cold resistance of a mammalian hibernator, Syrian
hamster
Daisuke Anegawa1,2), Yuichi Chayama2), Lisa Ando2), Hiroki Taii2),
Shuji Shigenobu3), Yuya Sato1,2), Masayuki Miura2), Yoshifumi Yamaguchi1)

Hibernation metabolism, physiology and development group, Institute of low
temperature science, Hokkaido University, Japan, 2Department of Genetics, Graduate
school of pharmaceutical science, The University of Tokyo, Japan, 3National institute forbasic biology, Japan
1

Alternative splicing of cold-inducible RNA-binding protein mRNA in
hypothermic animals
Yuuki Horii1), Hiroki Shimaoka1), Takahiko Shiina1), Yasutake Shimizu1,2)

Department of Basic Veterinary Science, Laboratory of Physiology, The United Graduate
School of Veterinary Sciences, Gifu University, Japan, 2Center for Highly Advanced
Integration of Nano and Life Sciences, Gifu University (G-CHAIN)

1

Physiome
1P-540Weighted gene co-expression network analysis in chronic kidneydisease and hemodialysis patients
Tomoyoshi Terada1,2), Hiromichi Akahori2), Yoshinori Muto1,2)

United Graduate School of Drug Discovery and Medical Information Sciences, Gifu
University, Japan, 2Department of Functional Biosciences, Gifu University School of
Medicine
1

1P-541

Reflected conduction caused by subcellular sodium channel redis­
tributions
Kunichika Tsumoto1,3), Takashi Ashihara2), Yasutaka Kurata1),
Yoshihisa Kurachi3)

1
Department of Physiology, Kanazawa Medical University, Japan, 2Department of
Cardiovascular Medicine, Shiga University of Medical Science, Japan, 3Department ofPharmacology, Graduate school of Medicine, Osaka University, Japan

1P-542

Simulation study on the nitrogen homeostasis disturbed by defect of
glutamine synthase in liver
Yuki Sasahara1,2), Masaru Tomita1,2,3), Yasuhiro Naito1,2,3)

1
Department of Environment and Information Studies, Keio University, Japan, 2Institutefor Advanced Biosciences, Keio University, 3Systems Biology Program, Graduation
School of Media and Governance, Keio University

Alternative Medicine (1)1P-543

Cortical cerebral blood flow response induced by manual acupunctureof the auricular region in rats
Sae Uchida1, Hiroshi Taniguchi1,2, Yoshie Ito1,3, Fusako Kagitani1,3Department of Autonomic Neuroscience, Tokyo Metropolitan Institute of Gerontology,
Japan, 2Tokyo Ariake Univ, Japan, 3Univ Human Art Sci, Japan1

1P-544

Influence of press tack needle acupuncture on the secretion of orexin
Aki Fujiwara1,2), Mana Tsukada1), Hideshi Ikemoto1), Toku Takahashi1,3),
Chiaki Tezuka1), Kana Takahashi1), Takuji Izuno1), Tadashi Hisamitsu1),
Masataka Sunagawa1)
1

Department of Physiology, School of Medicine, Showa University, Japan, 2Acupuncture

Adaptation, Environment & Evolution (1)/Physiome/Alternative Medicine (1)DAY 2

1P-539

& Moxibustion clinic Tenshinotamago, Japan, 3Department of Surgery, Medical Collegeof Wisconsin, USA

1P-546

Family history of hypertension has an effect on blood pressure
response with fragrance inhalation
Eriko Kawai1), Ryosuke Takeda2), Kosuke Saho1), Akemi Ota1),
Emiko Morita1), Daiki Imai1,2), Yuta Suzuki1,2), Hisayo Yokoyama1,2),
Kazunobu Okazaki1,2)

Department of Environmental Physiology for Exercise, Osaka City University Graduate
School of Medicine, Japan, 2Research Center for Urban Health and Sports, Osaka City
University, Japan1

1P-547

Physiological effects in CNS and the autonomic nervous system bydrinking jasmine tea
Mitsuyuki Ichinose, Yumi Shigihara

Department of Chemistry and Biological Science, Iwate University, Japan

1P-548Contribution of oxytocin to the anti-stress effect of Kampo medicine
Kamikihito
Mana Tsukada1), Tadashi Ikemoto1), Xiao Pen Lee2), Takaaki Matsuyama2),
Takuji Izuno1), Toku Takahashi1,3), Tadashi Hisamitsu1), Masataka Sunagawa1)

1
Department of Physiology, School of Medicine, Showa University, Japan, 2Departmentof Legal Medicine, School of Medicine, Showa University, Japan, 3Department ofSurgery, Medical College of Wisconsin, USA

1P-549Asymmetric Dimethylarginine and Endothelin B Receptor Modulationin Piper Sarmentosum Treated Rats
Maizura MOHD Zainudin, Taher Ft Elshami, Hidayatul Radziah Ismawi,
Fatimatuzzahra Hashim Fauzy, Tariq Abd Razak
Bms, Kulliyyah Medicine, International Islamic University Malaysia

1P-550

Theobromine increases plasma cholesterol levels by increasing
ABCA1 protein
Natsuki Hiruma1), Naotoshi Sugimoto2), Kentaro Matsuzaki3),
Eri Sumiyoshi3), Osamu Shido3), Masanori Katakura1)

1
Department of Pharmaceutical Sciences, University of Josai, Japan, 2Kanazawa
University, Department of Physiology, Japan, 3Shimane University, Department ofEnvironmental Physiology, Japan

1P-551

Nonequivalent effect of CO2-water bath on muscle fatigue caused byisotonic- and isometric-exercise
Masaaki Hashimoto1), Noriyuki Yamamoto2)

Physiology Laboratory, Center for Medical Education, Teikyo University of Science,
Japan, 2Department of Health Science, Japanese Red Cross Hokkaido College Nursing,Japan
1

1P-552

Change in the foot pressure distribution to dental occlusion adjustment
by micro tapping with paper
Masanori Takemura1), Akio Kawamura2), Kenichi Ichihashi1),
Mitsuharu Kaya3), Junzo Tsujita4)1
4

1P-553

Ichihashi Clinic, Japan, 2Kawamura Dental Clinic, 3Hyogo University of Health Science,
Institute of Health & Sports Medical Science

Analysis of Ultrasound Changes in Vastus Lateralis Muscle following
Transcutaneous Vacume Treatment

Junzo Tsujita1), Tomonari Shibutani2,6), Hiroshi Ueno3), Yoichiro Yamashita4),
Arijit Banerjee5), Mitsuharu Kaya6), Masanori Takemura7), Kenichi Ichihashi7)
Alternative Medicine (1)Institute of Health and Sports Medical Science, Japan, 2MJ Company, Japan,
JCRAFT, Japan, 4Osaka Electro-Communication University, Japan, 5Amgsaki-city Bordof Education, Japan, 6Hyogo University of Health Sciences, Japan, 7Ichihashi Clinic,
Japan

1
3

1P-554

Changes of HRV and resting-state amygdala functional connectivity
after SKY practicing
Ting-Wei Hsu1), Sheng-Kai Lee3), Chun-Yu Lin4), A-Min Huang2)

Alternative Medicine (1)DAY 2

Department of Physiology, College of Medicine, National Cheng Kung University,
Taiwan, 2Institute of Basic Medical Sciences, College of Medicine, National Cheng Kung
University, Taiwan, 3Interdisciplinary Neuroscience Graduate Program, Academia Sinica,
Taiwan, 4Department of Psychology, National Cheng Kung University, Taiwan
1