Amyloidosis and the COVID Vaccine
By Craig Paardekooper

PART A : Observations of amyloidosis by embalmers and funeral homes
Dr Vaughn - spike protein creates FIBRIN that is resistant to being broken down. See.... CEO of MedHelp Clinic, Alabama, Dr. Vaughn
Several undertakers and embalmers are speaking out regarding the discovery of rubbery amyloid clots within the veins of thevaccinated - sometimes of considerable length and resistant to breakdown by enzymes. These amyloid clots obstruct the infusion ofembalming fluids.
Dr John Campbell Amyloid clots are a real phenomenon following C19 vax - occurring in 20% of corpses in the UK. John Campbell
has received 250 samples of these clots. This is a completely new pathology since the jab rollout. See.... Dr John Campbell
Major Tom Haviland : USA Airforce These amyloid clots consist of amyloid protein, fibrin and platelet. They stretch like a rubberband. These clots are almost certainly the cause of death. The amyloid clots occur on the venous AND the arterial side of the body ordinary clots are usually restricted to the venous side. These clots are in the 6 to 10 inch range - though some can be up to 2 ft long.
Ordinary clots look and feel like jelly and dissolve in your hands. In comparison these amyloid clots are much tougher, rubbery,elastic and longer lasting. The amyloid clots grow to large size - blocking blood supply - they fill the entire blood vessel - taking its
shape - like a cast. They appear to grow without limit.
During 2020 44 embalmers saw these clots, but the incidence of these clots exploded in 2021. (In both cases, the spike protein is
associated with the clot formation.) In 2022 about 30% of corpses contained these amyloid clots. In 2023 the percentage decreased
to 20%. Embalmers have never seen this phenomenon before.
A fifth to a third of corpses have these clots. 20-30% of all people dying! In addition there has been a great increase in the incidenceof traditional jelly clots and micro-clotting.
A survey was sent to 50 national undertakers associations, and to 1700 funeral homes. 197 out of 269 embalmers were stillobserving these clots in 2023. See.... Major Tom Haviland's survey
John O'Looney - undertaker. See.... John O LooneyYet another embalmer speaks out. See.... Embalmer speaks out
Laura Jeffery - Director of Canadian funeral home for 37 years. See.... Laura Jeffrey
Brenton Faithfull - undertaker. See.... Brenton Faithful
Brenton Faithfull - undertaker - 95% of deaths are vaccinated and dying within 2 weeks of the jab. See.... Brendon Faithful
Dr Peterson Pierre - undertakers reporting deaths of vaccinated. See.... Dr Peterson Pierre
Wesley - undertaker. See.... Wesley
Richard Hirschman - undertaker. See.... Richard Hirschman
Richard Hirschman - undertaker. See.... Richard Hirschman Interview with Conservative Daily
Nicky King - Embalmer. See.... Nicky King
Funeral Directors and Embalmers Unite. See.... Funeral Directors and Embalmers

Physicians and embalmers reveal shocking vaccine injuries. See.... Physicians and embalmers
Wallace Hooker - Embalmer and funeral director testifies to white amyloid clot formation in vaccinated. See.... Wallace Hooker
Hooker is a funeral director for the independent Family and Friends Funeral Home in Wingate, Indiana with over 30 years
experience. Hooker serves on the advisory board of Worsham College of Mortuary Science, is a member of the BIE (British Instituteof Embalmers) and board member of the North American Division. He also travels around the nation providing lectures to otherembalmers on perfecting the process and navigating unusual problems. Hooker confirmed an increase in strange blood clots in thepast two years, not just witnessed by himself but by other morticians from across the nation who send him photographs.
“I have lectured four times so far this year," Hooker said. "I am asking questions and showing pictures of these clots in my Powerpoint, and routinely, everywhere I lecture, people say they are seeing these clots, and have not seen them prior to COVID.”
Anna Foster - Embalmer speaks out about amyloid clot formation in vaccinated. See.... Anna Foster

Part B : The Nature of Amyloid
What is a prion ?
All proteins are a string of aminoacids that fold locally to form alpha helixes or beta sheets. These then fold 3-dimensionally togive the protein its shape. A prion is a misfolded protein and they are associated with neuro-degenerative diseases like
Alzheimer’s disease. Prions cause other proteins to misfold around them

3. Why are prions resistant to being broken down ?
Prions are resistant to being broken down (proteolysis) by proteases. In normal proteins 43% are alpha helixes and only 3%
are beta sheets. However prions have far fewer alpha helixes (30%) and far more betasheets (43%). The betasheets are very
compact and this makes them resistant to proteases.

There are misfolded proteins in our bodies all of the time. If a protein is misfolded then the body deals with this in one of two
ways – chaperones refold it properly, or it is destroyed by proteases. However, prions are misfolded proteins that form betasheets, and these are not broken down by proteases.

4. What is amyloidosis ?
Amyloidosis comprises diseases that result from protein aggregation of fibrous proteins called amyloids. the beta-sheetalignment that gives the fibrils their visual appearance.
Rambaran RN, Serpell LC. Amyloid fibrils: abnormal protein assembly. Prion. 2008;2(3):112-117. doi:10.4161/pri.2.3.7488.

Part C : The SARS-nCoV-2 spike contains amyloidogenic peptides
Amyloidogenesis of SARS-CoV-2 Spike Protein - https://pubs.acs.org/doi/10.1021/jacs.2c03925
The protease neutrophil elastase (NE), which is overexpressed at sites of inflammation, cuts the spike protein into smaller
pieces. 7 of these smaller pieces are highly amyloidogenic. They produce amyloid deposits. These amyloid deposits don’t get
broken down, and they disrupt the normal functioning of cells and tissues.

“Amyloid fibril assays of peptide library mixtures and theoretical predictions identified seven amyloidogenic
sequences within the S-protein. All seven peptides in isolation formed aggregates during incubation at 37 °C.
Three 20-amino acid long synthetic spike peptides (sequence 192–211, 601–620, 1166–1185) fulfilled three amyloid fibril
criteria: nucleation dependent polymerization kinetics by ThT, Congo red positivity, and ultrastructural fibrillar
morphology. Full-length folded S-protein did not form amyloid fibrils, but amyloid-like fibrils with evident
branching were formed during 24 h of S-protein coincubation with the protease neutrophil elastase (NE) in vitro.
NE efficiently cleaved S-protein, rendering exposure of amyloidogenic segments and accumulation of theamyloidogenic peptide 194–203, part of the most amyloidogenic synthetic spike peptide. NE is overexpressed at
inflamed sites of viral infection.”“Neither NE nor SARS-CoV-2 S-protein incubated alone formed fibrils (Figure 2G–H). Fibrils were found only after coincubation of the two proteins”

“Fibrils from most of the synthetic peptides were detected within a few hours by at least one assay (Table 1, Figure 1).
Spike192, Spike601, and Spike1166 fulfilled all our amyloid criteria: sigmoidal ThT kinetics, Congophilicity, and fibrillar
ultrastructure (Figure 1, Table 1). Spike192 formed exceptionally well-ordered fibrils comparable to a mix of all
peptides (Figures 1C and S3C).”
As you can see from the charts above, fibrils resulting from spike regions 192, 601 and 1166 show strong growth, which was
ongoing at the end of the study.
These amyloid fibrins induced a resistance to breakdown of clots –“The addition of 10 μg/mL amyloid fibrils formed from a mix of the seven spike peptides (Table 1, Figure S3) during
fibrin formation decreased the fibrinolysis (Figure 4C). Furthermore, the addition of 2% fibrils (from 1 mg/mL stock,
total 20 μg/mL) of Spike192 and 194–203 increased persistent plasmin indigestible fibrin (Figure 4 D). As expected,
the more amyloidogenic Spike192 induced more plasmin resistant fibrin clots than did Spike194–203.”

Study author Per Hammarstrom says

“When the spike protein is cut up, it produces the exact piece of protein which, according to the researchers’ analysis,
is most likely to produce amyloid. This enzyme is released in large quantities from one type of white blood cells,
neutrophils, which are released early on during infections such as COVID-19. When the researchers mixed pure spike
protein with this enzyme, called neutrophil elastase, unusual fibrils were produced.”“We have never seen such perfect, but scary, fibrils as these ones from the amyloid-producing SARS-CoV-2 spike
protein and pieces thereof. The fibrils starting from the full-sized spike protein branched out like limbs on a body.
Amyloids don’t usually branch out like that. We believe that it is due to the characteristics of the spike protein.”
Study author Sofie Nystrom explained to Medical News Today:“Under normal circumstances, when we get an injury, fibrinogen that we have in our bloodstream is transformed into
fibrin to form clots. To prevent ‘over-clotting,’ there is another blood component, plasmin, that will dissolve the fibrin
clots when there are enough and ultimately get rid of all fibrin when it is not needed anymore.”“Our experiment shows that if fibrin is formed in the presence of spike amyloid, the plasmin cannot totally remove thefibrin clots”“Our finding that the SARS-CoV-2 Spike protein can form amyloid when cut by neutrophil elastase is probably an
important piece in the puzzle for many unsolved questions related to COVID-19 infection.”
See also - https://liu.se/en/news-item/mojlig-mekanism-bakom-gatfulla-symtom-vid-covid-19-upptackt

See also Amyloid and Hydrogel Formation of a Peptide Sequence from a Coronavirus Spike Protein | ACS Nano

It has been shown repeatedly in the literature that prion-like domains or peptides exist in
the spike protein of SARS-nCoV-2 and these are specific to SARS-2.
*** Tetz G, Tetz V. Prion-like Domains in Spike Protein of SARS-CoV-2 Differ across Its Variants and Enable Changes in Affinity
to ACE2. Microorganisms. 2022; 10(2):280. https://doi.org/10.3390/microorganisms10020280.
Misfolded Proteins - SUZANNE GAZDA M.D. (suzannegazdamd.com)*** Neurotoxic amyloidogenic peptides in the proteome of SARS-COV2: potential implications for neurological symptoms in
COVID-19 | Nature Communications
Highly efficient intercellular spreading of protein misfolding mediated by viral ligand-receptor interactions | Nature
Communications

Part D : Amyloid plaques are associated with diseases
Amyloidosis is a universal hallmark of
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CJD
Alzheimer's
Parkinson’s
Dementia
Type II Diabetes

Covid 19 vaccine is unique in having a high proportional reporting ratio for all of these. See Safety Signal - https://howbad.info
The number of Creutzfeldt-Jacob Disease (CJD)/prion disease reports in VAERS since the deployment of the COVID-19
injections has far surpassed the background rate for the U.S. for the year.

“There are 59 reports of CJD and prion diseases in VAERS to date (June 10, 2022). The background rate of CJD in the
United States is 1/1M per year. Since the population of the U.S. as of June 6, 2022 is ~334M5, then we would expect nomore than 334 cases of CJD reported. If we consider an extraordinarily low under-reporting factor (URF)6 of 6, thenwe have already surpassed the background expected number of cases reported by 20 reports. If we use thecalculated URF of 31 as referenced in (2), then we have 1,829 cases of prion diseases (CJD) in the U.S., to date. And thisis just data from VAERS. And this is just in the context of the COVID-19 shots. ~589M doses of the COVID-19 injections(Moderna, Pfizer and Janssen) have been doled out in the States as of June 6, 2022. This means that we are seeing~3.1 incidents of prion diseases/CJD per million Americans - 3 times the background rate. Already.”
Jessica Rose

Cases of CJD in temporal proximity to COVID vax
Prion diseases are no joke - by Jessica Rose (substack.com)
COVID-19 RNA Based Vaccines and the Risk of Prion Disease (scivisionpub.com)(PDF) COVID19 injection dose-effect on dynamics of Creutzfeldt-Jakob disease (researchgate.net)

Part E : Proportional Reporting Ratios
Safety Signal is available at https://howbad.info

Arterial effects of amyloidosis
You can use Safety Signal to search for each of these symptoms associated with the amyloid clots to see which vaccines
generate a high proportional reporting ratio. The arterial location of amyloid clots makes them distinct from blood clots thatare mainly located on the venous side of the body.
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Amyloidosis
Arterial catheterisation
Arterial occlusive disease
Arterial stenosis
Arterial thrombosis
Coronary arterial stent insertion
Embolism arterial
Peripheral arterial occlusive disease
Pulmonary arterial hypertension
Pulmonary arterial pressure

Biomarkers for amyloidosis
You can use Safety Signal to search for each of these biomarkers associated with the amyloid clots to see which vaccines
generate a high proportional reporting ratio
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D-DimerLight chain analysis
Blood alkaline phosphatase
Blood creatine
Troponin T
Troponin I
Brain natriuretic peptide
Blood fibrinogen

Diseases associated with amyloidosis
You can use Safety Signal to search for each of these diseases associated with the amyloid clots to see which vaccines
generate a high proportional reporting ratio
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Brain Fog
CJD
Alzheimer's
Parkinson’s
Dementia
Type II Diabetes
Disorientation
Memory loss

https://newsnetwork.mayoclinic.org/discussion/what-is-amyloidosis-and-10-signs-you-might-have-it/Part F : Mystery ORF genes in Covid Vaccine code for Amyloid
So far, we have seen evidence of a high incidence of amyloid clotting reported by embalmers since the rollout of the COVID
vaccines. We have also seen experimental evidence that the COVID spike protein rapidly generates amyloids in the presenceof neutrophil enzyme. Thirdly we have seen that COVID vaccines have a high proportional reporting ratio for symptoms
associated with amyloidosis.
A question arises as to how these adverse effects came to be associated with the Covid vaccines, and why the vaccines havenot been suspended pending an investigation.
When we look at the RNA sequence within the COVID vaccine, we find that other genes have been added besides the gene forthe spike protein, and these genes were kept hidden from the public.
The following is taken from Spider webs in the Pfizer closet - by Anandamide (substack.com)
Pfizer failed to report the 2nd largest sequence in the RNA. This is the mystery ORF of 1252 amino acids described by Beaudoin
et al. The protein sequence is given below –>Mystery_ORF_Under_Pfizer_SpikeMQYQLESSCVVQFHALQHGLRIVLVELAAAATATTALQAATAAGHATQHDCDHHDGNQSGDKAQPDVPGPLDVLLVLPQFLQVDQALVQIL
GHLVQPVDLFLDVHDAGIDSADIAQVHVGACVVLKVLVQFLFEAVQLGLQRVVHGIVHNADHDVAVARHEGVVGGDDLGLVEVPLCHEPMG
AVGHEHAFSRKVGFAVVADGWSGGEILLLSGHICHVQKHHAVRGRLREAHQVVALAAKVHSLALAQHTLRHLGGGQIGRGSNLGGSDQLLG
HVCLEALQSACDQSVDLHLGLRRVQSAQDIVQHRADGAELGGQLLDQGVQCLGIVVDHVLQLSQGACCAAQAVLDLADGAVELVGDQLLVLVQHILGHSDAVEPVGHLHSKGDLQSGACSKCPAACDCAGQQGRCVLGDHLIGQQRRQHCQSVKLLGANQIPGGNVAQTIAILLDEAGVGQCH
FVEQQVLDEAPLAGLARIGQNLAEIEAAEVLDRRGLVDLLHLGEHLLGVLVLFHGDPCQGSFQLGAEAAVLQQQVGALGGIAADVHGAVHAG
LGHGHRQDLCGHADGEVGGDSDRVVGVGHAVLGAQRHCVGNDALAGHASGSPVALCLCLVAGADSSADGDVALVAIVHVLGSDQTAGSGLKHIAAGGVHPPCRCQLIGVNGHGHFGTVHALVQHCHLIAGVGARGDHRHSAEAARGDVQDFQCLGISNGVCGIGDIPAKLLEWQELLVALCQHAGAGQAVEVEVHAFVLHEIGAFLRAAHCGRGMQQFEAQHHHSVGLVAHAVCGPKAVGLQWEVAVHACHAVTRLVAGLIDLGGDVPLEGLQIGLPEQPVPVIVVAADFGVQLVAVPGNHTAGEVVGQLVVVVGDVACLSRGNLPHFVSPDHEAVGVHVCEAQVVQLGRGHAVALECEEGG
EVVQHGVVGHAIADPLPVPGVHRGESGGIEHLVEGAQIGDIGEPHDGFGGLHPEVAGLVDALFHGEGLQGALCLAQRIQSTIHGVGDGAVLVV
LQQEGSRLQVAHIVSGGTSCPSAAAIARCQVASVQGQQCLKPGDVDADGQIHQGFQSREALRQIPAEVDRGVLAVDLEVAVDVLKHELAQVLEVALLAFQVHQERLGHVLEGAVVGAAVHPELAFHPALVVLVVVDVQEGVVAELELAHFDDHVGGVVHDQQALGLAVQCGAEDPASDDVGLLGAGKVHPVVEGQHGVVESLGAIGAGDGVEPGHVAEERQEQVLGRVQHAGSEHLVGVVHASGKAVGVORFs are painted in Green and Gold in the plasmid map below.
This large 1252 amino acid ORF was undisclosed and thisviolates FDA and WHO guidelines.

Analysis of Mystery ORF Region Using AmyloGram Tool
AmyloGram (uni.wroc.pl) shows that this ORF sequence is amyloidogenic. If the cells lining blood vessels start manufacturing
this amyloid, then the blood vessels will slowly fill with amyloid fibrils and the flow of blood will be gradually impeded.

The probability that the ORF sequence will generate amyloid is 0.8508 (1 is absolute certainty)
The percentage of the ORF sequence that is amyloid residue is 45.85%

Analysis of Pfizer Spike Region Using AmyloGram Tool

The probability that the SPIKE sequence will generate amyloid is 0.8627 (1 is absolute certainty)
The percentage of the SPIKE sequence that is amyloid residue is 28.15%(Note that the breakup of the SPIKE protein into amylogenic residues when exposed to neutrophil elastase will further
increase both the probability and percentage of amyloid formation)

So BOTH the ORF sequence AND the SPIKE sequence will result in the production of amyloid. In other words – as surely as thevaccine RNA generates spike protein (its intended purpose), it will also generate amyloid (a hidden intended purpose?)Using Uniprot to Identify What this Sequence Does
Anandamide found that the Mystery ORF's closest hit is to a protein involved in spider silk – called Spidroin. Other hits withlower E-values are to Collagen and Fibroin. Anandamide got no hits when he used BlastP to search for this sequence in the
NCBI database - it only showed up in UniProt.

I checked Uniprot to confirm Anandamide’s finding. I input the above sequence here - Tool results | UniProt
The top result was Spidroin as reported.

Curiously the Spidroin protein codes for natures toughest silk fibre, comparable in tensile strength to that of steel or Kevlar.
The RNA sequence is also similar to that of other fibrous materials – fibrin and collagen.
When blood vessel lining is exposed to the vaccine, the RNA codes for the Spike, but also codes for fibres akin to spider silk,
fibrin and collagen. The result is that endothelial cells begin to exude the tendrils of a fibrous mesh.
In addition, Spidroin is well known to be highly amyloidogenic.
Spider Silk Protein Forms Amyloid‐Like Nanofibrils through a Non‐Nucleation‐Dependent Polymerization Mechanism - Qi 2023 - Small - Wiley Online Library
Amyloidogenic nature of spider silk (wiley.com)

Note that the Spidroin sequence forms amyloid-like fibrils rapidly at 37 degrees Celsius.

A Reasonable Conclusion
Given the deliberate undisclosed inclusion of an amyloid producing sequence, as well as the inclusion of the spike sequencethat is also amyloidogenic, there is a distinct possibility that amyloid formation may be an intended effect of the Covid vaccine.
Despite these dangers, the failure of governments to withdraw or suspend the vaccine, or to investigate or even acknowledge
the risk, means that harms can no longer be considered an accident. It looks as if a conscious decision has been made to allow
and encourage a harmful protocol.
Branding the COVID vaccine a success, governments plan to replace more traditional vaccines with RNA ones, and childhood
vaccination continues unabated.