Plenary Lecture3【Room A】1F, Conference Center

March 30, Sat., 8:50-9:50

Chair: Junichi Nabekura (National Institute for Physiological Sciences, Japan)

Looking back on 30 years of autophagy research
PL3	-dynamic equilibrium of the cell-

Yoshinori Ohsumi
Institute of Innovative Research (IIR), Tokyo Institute of Technology, Japan

Special Lecture5
March 30, Sat., 17:20-18:10【Room B】3F, Conference Center

Chair: Yumiko Yoshimura (National Institute for Physiological Sciences, Japan)

SL5 Toward the Mysteries of Sleep

International Institute for Integrative Sleep
Medicine (WPI-IIIS), University of Tsukuba, Japan

Special Lecture6
March 30, Sat., 17:20-18:10【Room C】3F, Conference Center

Chair: Yukiko Hayashi (Tokyo Medical University, Japan)

The Beauty of Physiological Mechanisms in Skeletal
SL6	
Muscle Function and Fatigue

Graham Douglas Lamb
Department of Physiology, La Trobe University,
Australia

DAY 3

Masashi Yanagisawa

Special Lecture7
March 30, Sat., 17:20-18:10【Room F】5F, Conference Center

Chair: Yoichi Ueta (University of Occupational and Environmental Health, Japan)

The importance of understanding fetal physiology forSL7	detecting brain injury before birth

Laura Bennet
Department of Physiology, The University of
Auckland, New ZealandFAOPS2019 - PSJ and JSPFSM co-organizedSpecial Guest Talk
Talk in Japanese***Simultaneous tramslation to English will be available in the Main Hall (Room A).

March 30, Sat., 18:20-19:10【Room A】1F, Conference Center

Towards the Summit with Sport Science

Ms. Nao Kodaira special talk with Professor Masahiro Yuki

(Co-organized by The Physiological Society of Japan, and Japanese Society of PhysicalFitness and Sports Medicine)

Facilitator: Fusao Kato (Jikei University School of Medicine, Japan)

Aizawa Hospital; Gold medal in women’s 500m speed skating and silver
medal in women’s 1000m speed skating at the PyeongChang 2018
Winter Olympic Games, World record holder in women’s 1000m speed
skating.

Co-Speaker: Masahiro Yuki
Professor of the Shinshu University, Department of Sports Sciences
Education, Faculty of Education; a national coach of Japan Skating
Federation. Prof. Yuki coached Miss Kodaira since she was a student at
Shinshu University.

Interviewers and Commentators:
Yukio Nishimura (Tokyo Metropolitan Institute of Medical Science; PSJ, Japan)
Mikako Sunaga (Nippon Sport Science University; JSPFSM, Japan)
Schuichi Koizumi (University of Yamanashi, Japan)
Planning: Hidefumi Waki ( JSPFSM) , Fusao Kato (PSJ)DAY 3Main Guest Speaker: Nao KodairaSymposium36 (Local Organizing Committee Symposium)
March 30, Sat., 10:00-12:00
S36【Room A】1F, Conference Center

Inter-tissue communications underlying metabolic and feeding control
in living body(whole day symposium) part I

Chairs: Yasuhiko Minokoshi (National Institute for Physiological Sciences, Japan)

Shingo Kajimura (UCSF Diabetes Center, University of California, USA)

S36-1

Dietary nutrients and genes that regulate growth in C. elegans
Masamitsu Fukuyama1), Toshiaki Katada1,2)

Laboratory of Physiological Chemistry, Graduate School of Pharmaceutical
Sciences, University of Tokyo, Japan, 2Molecular Cell Biology Laboratory, ResearchInstitute of Pharmaceutical Sciences, Faculty of Pharmacy, Musashino University, Japan
1

S36-2

Nutri-developmental biology: nutritional adaptability and adipose
tissue remodeling
Tadashi Uemura1,5), Yukako Hattori1), Kaori Watanabe1), Taiichi Tsuyama1),
Yasutetsu Kanaoka1), Shoko Mizutani1), Kohei Shimono1),
Hironobu Uchiyama2), Shunsuke Yajima2,3), Masayoshi Watada4)

1Grad. Sch. of Biostudies, Kyoto Univ., Japan, 2NGRC, Tokyo Univ. of Agri., Japan, 3Dept. of
Bioscience, Tokyo Univ. of Agri., Japan, 4Grad. Sch. of Sci. and Eng., Ehime Univ.,
Japan, 5AMED-CREST, Japan

S36-3

The neural circuit for prey capture in zebrafish: from vision to the
hypothalamic feeding center
Koichi Kawakami, Akira Muto, Deepak Ailani

Division of Molecular and Developmental Biology, National Institute of Genetics, Japan

S36-4

Hypothalamic control of glucose metabolism in skeletal muscle
Yasuhiko Minokoshi1,2)

Division of Endocrinology and Metabolism, National Institute for Physiological Sciences,
Japan, 2Department of Physiological Sciences, School of Life Science, SOKENDAI The
Graduate University for Advanced Studies, Japan

S36-5

Fibroblast Growth Factor 21 mediates the inter-talk between major
metabolic regulators
Karen SL Lam

Department of Medicine, The University of Hong Kong, Hong Kong

Part II starts from 15:10 at the same room.

Symposium37 (Local Organizing Committee Symposium)【Room B】3F, Conference Center

March 30, Sat., 10:00-12:00
S37

Primate researches in Asian regions

Organizers: Suchinda Malaivijitnond (National Primate Research Center of ThailandChulalongkorn University, Thailand)

Atsushi Iriki (Center for Biosystems Dynamics Research, RIKEN, Japan)
S37-1

Suchinda Malaivijitnond1,2), Srichan Bunlungsup1), Taratorn Kemthong1),
Suthirote Meesawat1), Mallika Imwong3), Yuzuru Hamada4)

National Primate Research Center of Thailand-Chulalongkorn University, Thailand,
Department of Biology, Faculty of Science, Chulalongkorn University, Thailand,
3
Department of Molecular Tropical Medicine and Genetics, Faculty of Tropical Medicine,
Mahidol University, Thailand, 4Evolutionary and Morphology Section, Primate ResearchInstitute of Kyoto University, Japan
1
2

S37-2

Tool-Use Behavior in Burmese Long-Tailed Macaques and Possible
Adaptation for Learning
Michael D Gumert

Nanyang Technological University, Singapore

S37-3

Ruminant-Like Primate, Proboscis Monkey in Borneo
Ikki Matsuda1,2,3,4)

Chubu University Academy of Emerging Sciences, Japan, 2Wildlife Research Center,
Kyoto University, Japan, 3Japan Monkey Centre, Japan, 4Institute for Tropical Biology
and Conservation, Universiti Malaysia, Malaysia

1

S37-4

Neurobiology of Primate Brain-Body-Environment Interactions under
Evolutionary Perspectives
Atsushi Iriki

Lab. for Symbolic Cognitive Development, Center for Biosystems Dynamics Research,
RIKEN, Japan

DAY 3

Advantages of using Thai cynomolgus macaques for infectious
disease and cognitive researchSymposium38 (Local Organizing Committee Symposium)
March 30, Sat., 10:00-12:00
S38【Room C】3F, Conference Center

Cutting-edge research topics on skeletal muscle plasticity in health anddiseases(Co-organized by Japanese Society of Physical Fitness and Sports Medicine)

Organizers: Katsumasa Goto (Toyohashi SOZO University, Japan)

Gordon S Lynch (The University of Melbourne, Australia)
Hidefumi Waki (Juntendo University, Japan)

S38-1

Evidence for acute contraction-induced myokine secretion by cultured
myotubes
Nobuharu L Fujii

Department of Health Promotion Sciences, Graduate School of Human Health Sciences,
Tokyo Metropolitan University, Japan

S38-2

Sex difference in sarcopenia: mechanisms and interventions
Shuichi Machida

Graduate School of Health and Sports Science, Juntendo University Graduate School of
Health and Sports Science, Juntendo University, Japan

S38-3

Therapeutic potential of slow muscle programming for muscle
wasting and muscular dystrophy
Gordon S Lynch1), Justin P Hardee1), Karen J Martins1), Timur Naim1),
Stefan M Gehrig1), Gregory R Steinberg2), Rene Koopman1), James G Ryall1)

Centre for Muscle Research, Department of Physiology, The University of Melbourne,
Australia, 2Division of Endocrinology and Metabolism, Department of Medicine,
McMaster University, Australia
1

S38-4

Adiponectin and skeletal muscle - new insights and potential
implications
Katsumasa Goto

Department of Physiology, Graduate School of Health Sciences, Toyohashi SOZO
University, JapanSymposium39 (Local Organizing Committee Symposium)
March 30, Sat., 10:00-12:00
S39【Room D】4F, Conference Center

Cutting-Edge Optical Imaging of Neuronal Circuits and Synapses(Co-organized by Grant-in-Aid for Scientific Research on Innovative Areas ‘ABiS’ of MEXT, Japan)(Co-sponsored by Spectra-Physics)

Chair:
Haruo Kasai (The University of Tokyo, Japan)
Co-Chair: Junichi Nabekura (National Institute for Physiological Sciences, Japan)
Mechanical forces of spine enlargement detected by presynaptic
FRET/FLIM imaging
Haruo Kasai1,2), Hasan Ucar2), Jun Noguchi3), Satoshi Watanabe3),
Sho Yagishita1,2), Noriko Takahashi4)

Graduate School of Medicine, The University of Tokyo, Japan, 2Intl. Res. Ctr. for
Neurointelligence (WPI-IRCN), UTIAS, The Univ. of Tokyo, Japan, 3Natl. Ctr. of Neurol. andPsychiatry, Japan, 4Department of Physiology, Kitasato Univ. School of Medicine

1

S39-2

Multi-scale calcium imaging in the marmoset visual cortical network
Kenichi Ohki1,2)
1
2

S39-3

Department of Physiology, Graduate School of Medicine, University of Tokyo, Japan,
International Research Center for Neurointelligence (IRCN), University of Tokyo, Japan

Biochemical Signal Computation in Single Dendritic Spines
Ryohei Yasuda

Max Planck Florida Institute for Neuroscience, USA

S39-4

Super-resolution microscopy for neuroscience: new methods &applications
Valentin Nagerl

Interdisciplinary Institute for Neuroscience, University of Bordeaux, France

DAY 3

S39-1

Symposium40
March 30, Sat., 10:00-12:00
S40【Room E】4F, Conference Center

Social communication through sensory information

Sachine Yoshida (Toho University, Japan)
Chair:
Co-Chair: Masakazu Ide (National Rehabilitation Center for Persons with Disabilities, Japan)
S40-1

TRPM2 in the sensation for warmthChun-Hsiang Tan

Graduate Institute of Clinical Medicine, Kaohsiung Medical University, Taiwan

S40-2

Physiological and behavioral changes in infants during mother-infantinteraction
Sachine Yoshida

Department of Anatomy, Faculty of Medicine, Toho University, Japan

S40-3

Evolutionary changes in the function and diversity of color vision inprimates
Chihiro Hiramatsu

Department of Human Science, Faculty of Design, Kyushu University, Japan

S40-4

BodySharing: How we can share our body experiences
Emi Tamaki1,2)
1

Waseda University, Japan, 2H2L Inc., JapanSymposium41 (International Scientific Program Committee Symposium)【Room F】5F, Conference Center

March 30, Sat., 10:00-12:00
S41

Leveraging novel techniques to research and translate synaptictransmission and plasticity (ISPP, Iran)Chairs: Javad Mirnajafi-Zadeh (Tarbiat Modares University, Iran)

Vahid Sheibani (Neuroscience Research Center,Kerman University of Medical Sciences,
Iran)

Modulating the mesolimbic dopamine system by leptin: a circuit study
Azar Omrani, Veronne De Vrind, Inge G. Wolterink-Donselaar,
Mieneke Luijendijk, Roger A.H. Adan

Department of Transnational Neuroscience, University Medical Center Utrecht, The
Netherlands

S41-2

Addressing Therapeutic
Digiceuticals

Challenges

in

Neurosciencewith

Bechara John Saab1,2,3)
1
3

S41-3

Mobio Interactive, Canada, 2University of Zurich Psychiatric Hospital, Switzerland,Royal Society of Medicine, UK

Activity dependent LncRNA LoNA: Linking synaptic plasticity andmemoryQiang Liu, Juan Zhang, Dingfeng Li

University of Science and Technology of China, China

S41-4

Dual effects of dopamine on synaptic plasticity in normal andhyperexcitable brain
Javad Mirnajafi-Zadeh1), Mahboobeh Ahmadi1), Bechara John Saab2),
Yaghoub Fathollahi1), Nahid Roohi1)

Department of Physiology, Faculty of Medical Sciences, Tarbiat Modares University,
Iran, 2Research & Development, Mobio Interactive, Canada

1

S41-5

Does exercise reverse cognitive and synaptic plasticity deficits
following sleep deprivation?
Vahid Sheibani, Hakimeh Saadati, Amin Rajizadeh, Khadijeh Esmaeelpour
Neuroscience Research Center, Kerman University of Medical Sciences, Iran

DAY 3

S41-1

Sponsored Symposium

Symposium42

March 30, Sat., 10:00-11:30
S42【Room G】5F, Conference Center

Physiological function of royal jelly contributing to healthy longevity- The effectiveness on Locomotive syndrome, Menopausal disorders,
Infectious diseases -(Co-sponsored by Yamada Bee Company, Inc.)

Chair: Yoshinori Marunaka (Kyoto Industrial Health Association, General Incorporated
Foundation, Japan; Ritsumeikan University, Japan; Kyoto Prefectural
University of Medicine, Japan)

S42-1

Royal Jelly Prevents the Progression of Sarcopenia

Hongmei Wu, Xue Bao, Yeqing Gu, Shunming Zhang, Ge Meng, Kaijun Niu
Nutritional Epidemiology Institute and School of Public Health, China

S42-2

Mitigation of postmenopausal neurological disorders by administrationof royal jelly
Akira Minami

Department of Biochemistry, School of Pharmaceutical Sciences, University of
Shizuoka, JapanS42-3

10-hydroxydecanoic acid in royal jelly elicits antigen-specific mucosal
IgA response
Shogo Misumi

Department of Environmental and Molecular Health Sciences, Faculty of Life Sciences,
Kumamoto University, JapanSymposium43
March 30, Sat., 10:00-12:00
S43【Room H】5F, Conference Center

TRP channels and inflammation/fibrosis

Insuk So (Seoul National Univ, Korea)
Chair:
Co-Chair: Ryuji Inoue (Fukuoka University, Japan)
S43-1

The regulation of TRPC5 channel activity by S-glutathionylation andS-palmitoylation
1
Department of Physiology, Chosun University School of Medicine, Korea, 2Departmentof Physiology, Seoul National University College of Medicine, Korea

S43-2

TRPM7 mediated fibrogenesis in heart diseases
Lixia Yue, Zhichao Yue, Albert S. Yu, Jianlin Feng

Department of Cell Biology, Calhoun Cardiology Center, University of Connecticut
School of Medicine, USA

S43-3

The role of TRPM7 channel in pathogenesis of pulmonary arterial
hypertension and right heart failure
Lin Hai Kurahara1), Keizo Hiraishi1), Lixia Yue2), Aya Yamamura3),
Jianlin Feng2), Yaopeng Hu1), Mikiko Aoki4), Ryuji Inoue1)

Department of Physiology, Fukuoka University, Japan, 2Cardiology/Cell Biology,
University of Connecticut Health Center, USA, 3Department of Physiology, Aichi Medical
University, Japan, 4Department of Pathology, Fukuoka University, Japan

1

S43-4

Critical role of TRPC6 Targeting Hepatic Stellate Cell in Liver Fibrosis
Seung-Kuy Cha1,2), Kyu-Hee Hwang1,2), Ji-Hee Kim1,2), Soo-Jin Kim1,2),
Kyu-Sang Park1,2)
1
2

S43-5

Department of Physiology, Yonsei University Wonju College of Medicine, Korea,
Mitohormesis Research Center, Yonsei University Wonju College of Medicine, Korea

The non-neuronal protection of transient receptor potential vanilloid 1
in vascular system
Tzong-Shyuan Lee

Graduate Institute and Department of Physiology, College of Medicine, National Taiwan
University, Taiwan

DAY 3

Chansik Hong1), Insuk So2)

Symposium44 (International Scientific Program Committee Symposium)
March 30, Sat., 10:00-12:00
S44【Room I】5F, Conference Center

Cutting-edge approaches to long-lasting questions and novel aspects
of inward rectifier K+ channels -- A quarter-century anniversary of cDNA
isolation (ISPP, Israel)

Chairs: Eitan Reuveny (Weizmann Institute of Science, Israel)

Yoshihiro Kubo (National Institute for Physiological Sciences, Japan)

S44-1

New insights into K+ dependences of the strong inward rectifierpotassium channel Kir2.1
Keiko Ishihara

Division of Integrated Autonomic Function, Department of Physiology, Kurume
University School of Medicine, Japan

S44-2

The mechanism underlying rectification of ion flow in Kir2.1 andevolutionarily relevant channels
Chung-Chin Kuo

Department of Physiology and Neurology, National Taiwan University, Taiwan

S44-3

Regulation mechanisms of G-protein-gated inwardly rectifying K+
channel by small molecules
I-Shan Chen1,2), Chang Liu1,2), Yoshihiro Kubo1,2)

Division of Biophysics and Neurobiology, Department of Molecular and Cellular
Physiology, National Institute for Physiological Sciences, Japan, 2Department of
Physiological Sciences, School of Life Science, SOKENDAI, Japan

1

S44-4

The G protein coupled potassium channel in the mammalian brain
Eitan Reuveny

Weizmann Institute of Science, Israel

Symposium45
March 30, Sat., 10:00-12:00
S45【Room J】2F, Exhibition Hall

New molecular insights into the synaptic tagging and capture hypothesis

Tomonori Takeuchi (Aarhus University, Denmark)Chair:
Co-Chair: Sreedharan Sajikumar (National University of Singapore, Singapore)
S45-1

Behavioural and molecular insights in facilitating memory persistence
Szu-Han Wang

Inverse synaptic tagging : an inactive synapse-targeted mechanism
to capture activity-induced Arc
Haruhiko Bito1,3), Yuichiro Ishii1), Hiroyuki Okuno2)

Dept of Neurochemistry, The University of Tokyo Graduate School of Medicine, Japan,
Dept of Biochemistry and Molecular Biology, Kagoshima University Graduate Schoolof Medical and Dental Sciences, Japan, 3WPI-IRCN, The University of Tokyo Institutes for
Advanced Study, Japan

1
2

S45-3

Role of p75 neurotrophin receptor in sleep deprivation
changes in synaptic plasticity

inducedSajikumar SreedharanDepartment of Physiology, National University of Singapore, Singapore

S45-4

Rapid reversal of microRNA-induced silencing: a novel mechanism
mediating synaptic plasticity
Ted Abel1,2), Alan Jung Park4), Xiuping Fu3), Aparna P. Shah3),
Mahesh Shivarama Shetty1,2), Jay M Baraban3)

Iowa Neuroscience Institute, University of Iowa Carver College of Medicine andUniversity of Iowa, USA, 2Department of Molecular Physiology and Biophysics,
University of Iowa, USA, 3Solomon H. Snyder Department of Neuroscience, Johns
Hopkins School of Medicine, USA, 4Mortimer B. Zuckerman Mind Brain Behavior
Institute, Columbia University, USA
1

S45-5

Dopaminergic memory boostby two distinct novelty systems
Tomonori Takeuchi1,2,3)

Department of Biomedicine, Aarhus University, Denmark, 2The Danish ResearchInstitute of Translational Neuroscience (DANDRITE), Aarhus University, Denmark,3
Aarhus Institute of Advanced Studies (AIAS), Aarhus University, Denmark
1

DAY 3

Centre for Clinical Brain Sciences, University of Edinburgh, UK

S45-2

Symposium46
March 30, Sat., 10:00-12:00
S46【Room K】2F, Exhibition Hall

Plasticity of inhibitory signaling in Epilepsy: New Physiological
Mechanisms

Andrew Moorhouse (UNSW Sydney, Australia)
Chair:
Co-Chair: Atsuo Fukuda (Hamamatsu University School of Medicine, Japan)
S46-1

Neural circuits basis of temporal lobe epilepsy
Zhong Chen, Yi Wang, Cenglin Xu
Zhejiang University, China

S46-2

Conditional upregulation of KCC2 enhances inhibition during seizures
in mice
Chelsea Goulton1), M Watanabe2), D Cheung1,2), A Khoshaba1), H Indada2),
K Eto2,3), H Wake2,4), J Nabekura2,3), A Moorhouse1)

Department of Physiology, School of Medical Sciences, UNSW Sydney, Australia,
National Institutes for Physiological Sciences, Japan, 3The Graduate University for
Advanced Studies (SOKENDAI), Japan, 4Division of System Neuroscience, Kobe
University Graduate School of Medicine, Japan

1
2

S46-3

Human epilepsy and animal model with mutations in KCC2
Atsuo Fukuda

Department of Neurophysiology, Hamamatsu University School of Medicine, Japan

S46-4

Altered Cl-homeostasis during epileptogenesis
Claudio Rivera1,2,3)

1
Neuroscience Center, University of Helsinki, Finland, 2Inserm Unité 1249, INMED,
Marseille, 13009, France, 3Aix-Marseille Université, UMR S1249, Marseille, 13009, France

S46-5

Upregulating KCC2 as a Target for Seizure Therapies

Dennis Lawrence Cheung1), Chelsea Sarah Goulton2), Miho Watanabe3),
Junichi Nabekura1), Andrew John Moorhouse2)
Division of Homeostatic Development, National Insititute for Physiological Sciences,
Japan, 2School of Medical Sciences, Faculty of Medicine, UNSW Sydney, Australia,
3
Department of Neurophysiology, Hamamatsu University School of Medicine, Japan1

Sponsored Symposium

Symposium47【Room F】5F, Conference Center

March 30, Sat., 13:30-15:00
S47

New Frontiers in Regenerative Medicine of Renal Function(Co-sponsored by Shinkoiwa CIinic)

Chair: Yoshinori Marunaka (Kyoto Industrial Health Association, General Incorporated
Foundation, Japan; Ritsumeikan University, Japan; Kyoto Prefectural
University of Medicine, Japan)

Failure to sense energy depletion in chronic kidney disease
Eisei Sohara, Hiroaki Kikuchi, Shinichi Uchida

Department of Nephrology, Tokyo Medical and Dental University, Japan

S47-2

Kidney reconstitution from iPS cells based on developmental biology
Ryuichi Nishinakamura

Institute of Molecular Embryology and Genetics, Kumamoto University, Japan

S47-3

Next generation Therapy for dialysis patients using iPS cells
Takashi Yokoo

Department of Internal Medicine, Jikei University School of Medicine, Japan

DAY 3

S47-1

Symposium48 (Local Organizing Committee Symposium)
March 30, Sat., 15:10-17:10
S48【Room A】1F, Conference Center

Inter-tissue communications underlying metabolic and feeding control
in living body(whole day symposium) part II

Chairs: Yasuhiko Minokoshi (National Institute for Physiological Sciences, Japan)

Shingo Kajimura (University of California, USA)

S48-1

Central insulin action and hepatic glucose metabolism
Hiroshi Inoue1,2), Yuka Inaba1), Emi Hashiuchi2)

1
Institute for Frontier Science Initiative, Kanazawa University, Japan, 2Graduate Schoolof Medical Sciences, Kanazawa University, Japan

S48-2

Contribution of the hepatokine selenoprotein P to the various
pathologies of type 2 diabetes
Hirofumi Misu

Department of Endocrinology and Metabolism, Kanazawa University, Japan

S48-3

NeuroImmunoMetabolic regulation of cardiac physiology and heart
failureIchiro Manabe

Chiba University, Japan

S48-4

JMJD1A mediates acute and chronic thermogenic responses throughcomplementary mechanisms
Juro Sakai1,2)

1
Tohoku University School of Medicine, Molecular Physiology div., Japan, 2The Universityof Tokyo, RCAST, Metabolic Medicine div., Japan

S48-5

Metabolic adaptation and maladaptation in the adipose tissue
Shingo Kajimura

University of California, USASymposium49 (Local Organizing Committee Symposium)
March 30, Sat., 15:10-17:10
S49【Room B】3F, Conference Center

Frontiers in pain physiology - from detection to the survival behavior(under the auspices of Japanese Association for Study of Pain)

Chairs: Fusao Kato (Jikei University, Japan)

Seog Bae Oh (Seoul National University, Korea)

S49-1

proteins

modulatepain

Xu Zhang

Institute of Neuroscience and State Key Laboratory of Neuroscience, CAS Center for
Excellence in Brain Science, Shanghai Institutes for Biological Sciences, Chinese
Academy of Sciences, China

S49-2

Immune Response to Peripheral Nerve Injury: Implication for Neuropathic Pain
Seog Bae Oh

Department of Neurobiology and Physiology School of Dentistry, Department of Brain
and Cognitive Sciences College of Natural Sciences, Seoul National University, Korea

S49-3

How opioids and noxious stimuli regulate delivery of nociceptive
information to the amygdala
Elena Bagley

Discipline of Pharmacology and Charles Perkins Centre, University of Sydney, Australia

S49-4

Lateralized amygdala plasticity independent of bilateral parabrachialactivity in inflammatory pain
Yukari Takahashi1,2), Yuta Miyazawa1,2), Yae K Sugimura1,2), Fusao Kato1,2)1Dept Neurosci, Jikei Univ Sch Med, Japan, 2Cntr Neurosci Pain, Jikei Univ Sch Med,
Japan

S49-5

No pain no gain and no protection: Chronic pain protects heart fromischemia-reperfusion injury
Chien-Chang Chen, Yi-Fen Cheng, Ya-Ting Chang, Wei-Hsin Chen,
Hsi-Chien Shih, Bai-Chuiang Shyu
Institute of Biomedical Sciences, Academia Sinica, Taiwan

DAY 3

Primary sensory neuron-secretedtransmission in spinal level

Symposium50 (International Scientific Program Committee Symposium)
March 30, Sat., 15:10-17:10
S50【Room C】3F, Conference Center

Maternal influences on offspring development (AuPS, Australia)

Chair: Deanne Hryciw (Griffith University, Australia)
S50-1

Fetal origins of osteoarthritis induced by maternal xenobiotic
exposure
Hui Wang1,4), Liaobin Chen3,4), Hao Kou2,4), Yinxian Wen3,4)

Department of Pharmacology, School of Basic Medical Sciences, Wuhan 430071,
China, 2Department of Pharmacy, Zhongnan Hospital of Wuhan University, Wuhan
430071, China, 3Department of Orthopedic Surgery, Zhongnan Hospital of Wuhan
University, Wuhan 430071, Chin, 4Hubei Provincial Key Laboratory of Developmentally
Originated Disease, Wuhan 430071, China
1

S50-2

How can maternal deprivation cause neurodevelopmental disorders?
Ken-Ichi Ohta, Shingo Suzuki, Takanori Miki

Department of Anatomy and Neurobiology, Faculty of Medicine, Kagawa University,
Japan

S50-3

Role of linoleic acid in offspring development: Focus on inflammationand the placenta
Deanne Helena Hryciw1,2), Nirajan Shrestha3), James SM Cuffe3),
Olivia J Holland3), Amanda Cox3), Andrew Bulmer3), Anthony V Perkins3),
Andrew J McAinch2,4)1School of Environment and Science, Griffith University, Australia, 2Institute for Healthand Sport, Victoria University, Australia, 3School of Medical Science, Griffith University,
Australia, 4Australian Institute for Musculoskeletal Science (AIMSS), Victoria University,
AustraliaSymposium51【Room D】4F, Conference Center

March 30, Sat., 15:10-17:10
S51

Cutting-edge Research in Neural Network Dynamics(Organized by Women in Physiology of Japan (WPJ))

Chair:
Akiko Arata (Hyogo College of Medicine, Japan)
Co-Chair: Yumiko Yoshimura (National Institute for Physiological Sciences, Japan)
S51-1

Seung-Hee Lee

Department of Biological Sciences, KAIST, Korea

S51-2

Involvement of V1 neurons preferring low-contrast stimuli in difficult
orientation discrimination
Rie Kimura1,2), Yumiko Yoshimura1,2)

Division of Visual Information Processing, National Institute for Physiological Sciences,
Japan, 2Department of Physiological Sciences, SOKENDAI, Japan

1

S51-3

mGRASP for high-resolution structural and functional synapse
mapping
Jinhyun Kim1,2)

1
Korea Institute of Science and Technology, Korea, 2University of Science andTechnology, Korea

S51-4

Synaptic communication from subplate neurons controls neuronalmigration in the developing neocortex
Chiaki Ohtaka-Maruyama

Neural Network Project, Tokyo Metropolitan Institute of Medical Science, Japan

DAY 3

State-dependent multi-sensory integration in the posterior parietal
cortexSymposium52
March 30, Sat., 15:10-17:10
S52

Sports and Brain【Room E】4F, Conference Center(Co-sponsored by De Luca Foundation)

Chair:
Kazuyuki Kanosue (Waseda University, Japan)
Co-Chair: Yukio Nishimura (Tokyo Metropolitan Institute of Medical Science, Japan)
S52-1

Functional organization of spinal motor map in sport athletes
Toshiki Tazoe

Neural Prosthesis Project, Department of Dementia and Higher Brain Function, Tokyo
Metropolitan Institute of Medical Science, Japan

S52-2

Neural Correlates of Intuitive Decision - Making in Soccer
Xiaohong Wan1,2), Tomohisa Nagano3), Keiji Tanaka2)

School of Pychology, Beijing Normal University, China , 2Cognitive Brain Mapping
Laboratory, RIKEN Center for Brain Science, Japan, 3Faculty of Policy Management, Keio
University, Japan

1

S52-3

The Paralympic Brain - Brain reorganization appeared in Paralympic
athletes Kimitaka Nakazawa

Department of Life Sciences, The University of Tokyo, Japan

S52-4

Why is muscle relaxation difficult during sports?
Kouki Kato, Kazuyuki Kanosue

Faculty of Sport Sciences, Waseda University, JapanSymposium53【Room F】5F, Conference Center

March 30, Sat., 15:10-17:10
S53
Chair:

Dynamic signaling of axon and presynaptic terminals revealed by direct
recordings

Shin-ya Kawaguchi (Society-Academia Collaboration for Innovation, Kyoto University,
Japan)

Co-Chair: Haruyuki Kamiya (Hokkaido University Graduate School of Medicine, Japan)
Control of synaptic outputs by dynamic axonal excitability
Shin-Ya Kawaguchi1,2,3)

1
Society-Academia Collaboration for Innovation, Kyoto University, Japan, 2Graduate
School of Science, Kyoto University, Japan, 3Institute for Advanced Study, Kyoto
University, Japan

S53-2

Analog signaling in molecular layer interneurons of the cerebellar
cortexFederico F Trigo1,2)
1

S53-3

Brain Physiology Laboratory, France, 2University Paris Descartes, France

Presynaptic properties at lemniscal fiber terminals in the somato­
sensory thalamus
Mitsuharu Midorikawa, Mariko Miyata

Department of Physiology, Division of Neurophysiology, School of Medicine, Tokyo
Women's Medical University, Japan

S53-4

Regulation of neuronal signaling by axonal ion channels and neuro­transmitter receptors
Yousheng Shu

State Key Laboratory of Cognitive Neuroscience and Learning, Beijing Normal
University, China

S53-5

Dynamic control of spike signaling by axonal afterdepolarization
Haruyuki Kamiya

Department of Neurobiology, Hokkaido University Graduate School of Medicine, Japan

DAY 3

S53-1

Symposium54
March 30, Sat., 15:10-17:10
S54【Room G】5F, Conference Center

Ca2+ signaling in health and disease

Xiaoqiang Yao (Chinese University of Hong Kong, China)
Chair:
Co-Chair: Ryuji Inoue (Fukuoka University School of Medicine, Japan)
S54-1

A multi-hierarchical study on the arrhythmogenicity of a Ca-activatedcation channel TRPM4
Ryuji Inoue1), Yaopeng Hu1), Yanghua Shen2), Keizo Hiraishi1),
Lin Hai Kurahara1), Jun Ichikawa1), Tomohiro Numata1), Xin Zhu2)

1
Department of Physiology, Fukuoka University School of Medicine, Japan, 2Departmentof Biomedical Information Technology, Aizu University, Japan

S54-2

TRPP2 acts through autophagy to exert cyto-protective role in humanstem cell-derived cardiomyocytes
Xiaoqiang Yao, Jun Lu

School of Biomedical Sciences, Chinese University of Hong Kong, China

S54-3

Ca2+ signaling in early fate decision of cardiac lineage cells
Huangtian Yang, Yijie Wang, Jijun Huang, Ji Liang, Liming Chu

Laboratory of Molecular Cardiology, Shanghai Institutes for Biological Sciences, Chinese
Academy of Sciences, China

S54-4

Use of tetrandrine to treat flavivirus infection
Jianbo Yue, Lihong Huang

Department of Biomedical Sciences, City University of Hong Kong, China

S54-5

Structure-function Study of TRPP Channels
Xiaodong Liu1), Yuxia Liu1,2)

Beihang University, China, 2Tsinghua University, China

1Symposium55
March 30, Sat., 15:10-17:10
S55【Room H】5F, Conference Center

Brain pathways linking between emotion, behaviour and autonomic
responses

Youichirou Ootsuka (Flinders University, Australia)
Chair:
Co-Chair: Tomoyuki Kuwaki (Kagoshima University, Japan)
S55-1

Yoko Ikoma1,4), Ikue Kusumoto1), Akihiro Yamanaka2),
Youichirou Ootsuka1,3), Tomoyuki Kuwaki1)

Department of Physiology, Graduate School of Medical & Dental Sciences, Kagoshima
University, Japan, 2Department of Neuroscience II, Research Institute of Environmental
Medicine, Nagoya University, Japan, 3Centre for Neuroscience, Department of Human
Physiology, School of Medicine, Flinders University, Australia, 4Super-network Brain
Physiology, Graduate School of Life Sciences, Tohoku University, Japan
1

S55-2

Lateral habenula-ventral tegmental area pathways for emotional
hyperthermia
Youichirou YoYo Ootsuka1), Mariana Brizuela1), Steven J Swoap2),
Anna Antipov1), William W Blessing1)

Centre for Neuroscience, College of Medicine and Public Health, Flinders University,
Australia, 2Department of Biology, Williams College, USA

1

S55-3

The medial amygdala is critical for endocrine and behavioural
responses to emotional stress
Christopher Vincent Dayas

School of Biomedical Sciences and Pharmay, University of Newcastle, Australia

S55-4

Striatopallidal output pathways promoting and preventing motivatedbehaviour
Gavan McNally

School of Psychology, UNSW Sydney, Australia

DAY 3

Contribution of medullary raphe serotonergic neurons in the stressinduced autonomic responses

Symposium56
March 30, Sat., 15:10-17:10
S56【Room I】5F, Conference Center

Optical neuroscience: reading and manipulating neural computation
behind cognition, memory, and behavior

Masakazu Agetsuma (National Institute for Physiological Sciences, Japan)
Chair:
Co-Chair: Luis Alberto Carrillo-Reid (National Autonomous University of Mexico, Mexico)S56-1

Multiscale understanding of synaptic pathology of psychiatricdisorders
Akiko Hayashi-Takagi

Lab of Medical Neurosci, IMCR, Gunma Univ, Japan

S56-2

Population coding of fear memory in prefrontal cortex
Masakazu Agetsuma1,2,3), Yoshiyuki Arai3), Atsushi Kasai4),
Hitoshi Hashimoto4), Takeharu Nagai4)

Division of Homeostatic Development, National Institute for Physiological Sciences,
Japan, 2Japan Science and Technology Agency, PRESTO, Japan, 3The Institute of
Scientific and Industrial Research, Osaka University, Japan, 4Graduate School of
Pharmaceutical Sciences, Osaka University, Japan
1

S56-3

SLM-based methods for 3d control and imaging in the brain
Darcy Peterka

Zuckerman Mind Brain Behavior Institute, Columbia University, USA

S56-4

Manipulation of behavioral performance by targeted activation ofcortical ensembles
Luis Alberto Carrillo-Reid

Department of Developmental Neurobiology and Neurophysiolgy, National
Autonomous University of Mexico, Mexico

S56-5

Brain states through brainwide neuromodulation in zebrafish
Misha Benjamin Ahrens

Howard Hughes Medical Institute, Janelia Research Campus, USASymposium57
March 30, Sat., 15:10-17:10
S57【Room J】2F, Exhibition Hall

Alternative GPCR and G-protein signaling in cardiovascular disease
and therapy

Utako Yokoyama (Yokohama City University, Japan)
Chair:
Co-Chair: Motohiko Sato (Aichi Medical University, Japan)
S57-1

Hemal PatelUC San Diego, USA & VA San Diego, USA

S57-2

Role of activator of G-protein signaling (AGS) 8 in neovascularization
Hisaki Hayashi, Motohiko Sato

Department of Physiology, Aichi Medical University, Japan

S57-3

Uncovering new GPCR signaling pathways in prostaglandin E2mediated vascular inflammation
Utako Yokoyama, Al Mamun, Hiromi Taro, Yoshihiro Ishikawa
Cardiovascular Research Institute, Yokohama City University, Japan

S57-4

Age-dependent dimer formation of AT1R and P2Y6R promotes
angiotensin II-induced hypertension
Akiyuki Nishimura1), Caroline Sunggip2), Takuro Numaga-Tomita2,3,4),Motohiro Nishida1,2,3,4)

Department of Translational Pharmaceutical Sciences, Graduate School of
Pharmaceutical Sciences, Kyushu University, Japan, 2National Institute for Physiological
Sciences (NIPS), National Institutes of Natural Sciences, Japan, 3Department of Creative
Research, Exploratory Research Center on Life and Living Systems (ExCELLS), National
Institutes of Natural Sciences, Japan, 4School of Life Sciences, SOKENDAI, Japan
1

S57-5

A novel physiological role of tetrahydrobiopterin, a key GTP
metabolite, in cardiovascular system
Jin Han1), Hyoung Kyu Kim1), Ippei Shimizu2), Tohru Minamino2),
Bernd Nilius3)

Cardiovascular and Metabolic Disease Center, Inje University, Korea, 2Department of
Cardiovascular Biology and Medicine, Niigata University Graduate School of Medical
and Dental Sciences, Japan , 3KU Leuven, Department of Cellular and Molecular
Medicine, Belgium

1

DAY 3

The Membrane-Intracellular Organelle Interface: A Compartment for
GPCR Regulation of Cell Physiology

Symposium58
March 30, Sat., 15:10-17:10
S58【Room K】2F, Exhibition Hall

Zinc physiology and pathophysiology

Toshiyuki Fukada (Tokushima Bunri University, Japan)
Chair:
Co-Chair: Taiho Kambe (Kyoto University, Japan)
S58-1

Role of the zinc homeostatic system in skin and skeletal muscle
development
Toshiyuki Fukada

Faculty of Pharmaceutical Sciences, Tokushima Bunri University, Japan

S58-2

Zn sensitivity of Hv1 channel: an evolutionary perspective
2+

Adisorn Ratanayotha1,2), Takafumi Kawai1), Yasushi Okamura1)

Laboratory of Integrative Physiology, Department of Physiology, Graduate School of
Medicine, Osaka University, Japan, 2Department of Anatomy, Faculty of Medicine Siriraj
Hospital, Mahidol University, Thailand
1

S58-3

How does zinc signaling control the fate determination of beige fat
cells?
Ayako Fukunaka

Institute for Molecular & Cellular Regulation Gunma University, Japan

S58-4

Physiology and biochemistry of zinc enzymes
Taiho Kambe

Graduate School of Biostudies, Kyoto University, JapanSymposium59
March 30, Sat., 15:10-17:10
S59【Room M】3F, Exhibition Hall

Contribution of microglia in health and disease of the brain

Mami Noda (Kyushu University, Japan)
Chair:
Co-Chair: Bo Peng (Shenzen Institutes of Advanced Technology, China)
S59-1

Deciphering the origins of repopulated microglia in the central
nervous system
Chinese Academy of Sciences, China

S59-2

Microglia in Post-stroke Axon Remyelination and Tissue Repair
Dandan Sun

Department of Neurology, University of Pittsburgh, USA

S59-3

Roles of lipid receptors expressed by microglia in traumatic nerve
injuryHiroshi Kiyama

Department of Functional Anatomy & Neuroscience, Nagoya University Graduate
School of Medicine, Japan

S59-4

Sex- and age-dependent effect of thyroidism on microglia and brain
function
Mami Noda

Kyushu University, Graduate School of Pharmaseutical Sciences, JapanDAY 3

Bo PengLuncheon Seminar6

Talk in Japanese【Room A】1F, Conference Center

March 30, Sat., 12:20-13:20
LS6

Plasmalogen: The effects on Alzheimer's disease and its mechanism(Co-sponsored by The Japanese Plasmalogen Society)

Chair: Junichi Nabekura (National Institute for Physiological Sciences, Japan)
LS6-1

Plasmalogens improve the memory and other functions in Alzheimer’s
disease and Mild Cognitive Impairment
Takehiko Fujino

The Japanese Plasmalogen Society, Japan

LS6-2

Plasmalogens are the key phospholipids to regulate memory andneuro-inflammation in the brain
Hossain Md Shamim

Faculty of Medical Sciences, Kyushu University, Japan

Luncheon Seminar7

【Room B】3F, Conference Center

March 30, Sat., 12:20-13:20
LS7

Talk in Japanese

Frailty and Ninjin’yoeito(Co-sponsored by Kracie Pharmaceutical, Ltd.)

Chair: Yoshinori Marunaka (Kyoto Industrial Health Association, General Incorporated
Foundation, Japan; Ritsumeikan University, Japan; Kyoto Prefectural
University of Medicine, Japan)

LS7-1

Anti-frailty strategy:Ninjin-yoeito stimulates appetite center andrestores feeding
Toshihiko Yada1,2)

Kansai Electric Power Medical Research Institute Center for Integrative Physiology,
Division of Integrative Physiology, Japan, 2Kobe University Graduate School of Medicine
Division of System Physiology, Japan
1

LS7-2

Frailty and Ninjin’yoeito - toward healthy longevity
Akio Inui

Kagoshima University Graduate School of Medical and Dental Sciences Pharmacological
Department of Herbal Medicine, Japan

Luncheon Seminar8
【Room C】3F, Conference Center

March 30, Sat., 12:20-13:20
LS8

Imaging intracellular temperature using fluorescence lifetime imaging
microscopy (FLIM) reveals novel thermal signaling(Co-sponsored by Leica Microsystems K.K.)

Chair: Makoto Tominaga (National Institute for Physiological Sciences (NIPS), Japan; Exploratory
Research Center on Life and Living Systems (ExCELLS), Japan)
1
Graduate School of Pharmaceutical Sciences, The University of Tokyo, Japan, 2PRESTO,
JST, Japan

Luncheon Seminar9
March 30, Sat., 12:20-13:20
LS9

Talk in Japanese【Room D】4F, Conference Center

ABiS Luncheon Event: Neurophysiological Sciences Assisted by
Imaging Support Network(Co-sponsored by Grant-in-Aid for Scientific Research on Innovative Areas“Advanced Bioimaging Support (ABiS)” of MEXT, Japan)

Chair: Masanobu Kano (National Institute for Physiological Sciences, Japan; University of Tokyo,
Japan)

LS9-1

Support system for the electron microscopic investigation ofultrastructure and molecular localization
Yugo Fukazawa

University of Fukui, Japan

LS9-2

Causal link between cerebellar LTD and motor learning revealed by
the optogenetic tool PhotonSABER and SDS-FRL
Shinji Matsuda

University of Electro-Communications, Japan

LS9-3

What’s “ABiS”
ABiS-Office

DAY 3

Kohki Okabe1,2)

Luncheon Seminar10
March 30, Sat., 12:20-13:05
LS10

Talk in Japanese【Room H】5F, Conference Center

The effects of Bedding based on Physiology of sleep(Co-sponsored by airweave inc.)

Chair: Motohiro Ozone (The Jikei University school of Medicine, Japan)
LS10-1

Investigation of sleep surface selection and its influence on sleep
Shintaro Chiba1,2)

1
Ota Memorial Sleep center, Japan, 2Department of Otorhinolaryngology, The Jikei
University school of Medicine, Japan

LS10-2The effects of high rebound mattress topper on sleep and approachto the medical field
Motokuni Takaoka
airweave inc., Japan

Technical Workshop2【Room G】5F, Conference Center

March 30, Sat., 12:20-13:20
TW2

How to take advantage of new tools and techniques with Narishige
products(Co-sponsored by NARISHIGE SCIENTIFIC INSTRUMENT LAB.)

Chair: Hidemasa Furue (Hyogo College of Medicine, Japan)
TW2-1

Akihiro Yamanaka

Research Institute of Environmental Medicine, Nagoya University, Japan

TW2-2

Intrinsic plasticity of cerebellar Purkinje cells in motor learning circuits:
Application of micro manipulators to patch clamping
Sang Jeong Kim

Department of Physiology, Seoul National University College of Medicine, Korea

TW2-3

Synaptic responses evoked by optogenetic activation of descending
pain modulatory system: Recording from anesthetized animals
placed in a stereotaxic apparatus
Hidemasa Furue

Department of Neurophysiology, Hyogo College of Medicine, Japan

DAY 3

Adeno-associated virus vector micro injection into mice brain toreveal function of neural circuitry involved in the regulation of sleep/
wakefulness

Iran Lunch
March 30, Sat., 12:20-13:20【Room I】5F, Conference Center

Educational Lecture2
March 30, Sat., 8:00-8:40
EDL2
EDL2-1

Talk in Japanese【Room D】4F, Conference Center

Mechanomedicine
Mechanomedicine
Keiji Naruse

Cardiovascular Physiology, Graduate School of Medicine, Dentistry and Pharmaceutical
Sciences, Okayama University, Japan

DAY 3

This lecture provides the credit in the qualification update for Physiology
Educator accredited by Physiological Society of Japan.

Poster (The 2nd Poster Presentation Day)
March 30, Sat., 13:20-14:10/14:10-15:00

1F, Exhibition Hall

★Young Scientist Travel Award, ★★Young Scientist Travel Award & Masao Ito Memorial Award

PSJ Awards
see P.96~97 for each presentation.

Skeletal muscle & locomotion (2)2P-001

Application of CGRP upregulates MyHC I mRNA through cAMPdependent manner in C2C12 cells
Yoshiaki Mori1), Junko Yamaji2)

Department of Rehabilitation Sciences, Kansai University of Welfare Sciences, Japan,
Department of Nutrition Sciences, Kansai University of Welfare Sciences, Japan1
2

2P-002Essential role of calcineurin but not cAMP in mRNA expression of
MyHC II and IL-6 in murine myocytes
Junko Yamaji1), Yoshiaki Mori2)

1
Dept. of Nutrition sciences, Kansai University of Welfare Sciences, Japan, 2Dept. of
Rehabilitation sciences, Kansai University of Welfare Sciences, Japan

2P-003Differential Scanning Calorimeter reveals interaction between waterand myoproteins
Naoya Nakahara1), Tetsuo Ohno1), Masako Kimura2), Sumiko Kimura1),
Shigeru Takemori1)

1Dept. Mol. Physiol., Jikei Univ. Sch. Med., Japan, 2Dept. Integr. Physiol., Kagawa Nutri.
Univ., Japan

2P-004Microscopic heat pulses induce activation of cardiac thin filaments in
the in vitro motility assay
Shuya Ishii1), Kotaro Oyama1,2,3,4), Tomomi Arai1,2), Hideki Itoh1,5),
Seine A. Shintani6), Madoka Suzuki4,7), Fuyu Kobirumaki-Shimozawa2),
Shin’Ichi Ishiwata8), Norio Fukuda2)

Department of Physics, School of Advanced Science and Engineering, Waseda
University, Japan, 2Department of Cell Physiology, The Jikei University School of
Medicine, Japan, 3Quantum Beam Science Research Directorate, National Institutes for
Quantum and Radiological Science and Technology, Japan, 4PRESTO, Japan Scienceand Technology Agency, Japan, 5Epithelial Biology Laboratory, Institute of Medical
Biology, Agency for Science, Technology and Research, Singapore, 6Department
Biomedical Sciences, Chubu University, Japan, 7Institute for Protein Research, Osaka
University, Japan, 8Faculty of Science and Engineering, Waseda University, Japan1

2P-005Functional organization of spinal motor map depends on sport
experience
Kazutake Kawai1,2), Toshiki Tazoe2), Yukio Nishimura2)

1
College of Sports Sciences, Nihon University, Japan, 2Neural Prosthesis Project,
Department of Dementia and Higher Brain Function, Tokyo Metropolitan Institute ofMedical Science

2P-006

Thalamocortical Axon Activity in Motor Cortex Exhibits Layer-Specific
Dynamics during Motor Learning
Yasuhiro R. Tanaka1,2,3), Yasuyo H. Tanaka1,2,3), Masashi Kondo1,2),
Shin-Ichiro Terada1,2,4), Yasuo Kawaguchi3,5,6), Masanori Matsuzaki1,2,3,5,7)Skeletal muscle & locomotion (2)/PSJ Awards

Department of Physiology, The University of Tokyo, Japan, 2Division of Brain Circuits,
NIBB, Japan, 3CREST, JST, Japan, 4Graduate School of Biostudies, Kyoto University, Japan,
5
SOKENDAI, Japan, 6Division of Cerebral Circuitry, NIPS, Japan, 7WPI-IRCN, The Universityof Tokyo Institutes for Advanced Study, Japan1

2P-007Leg muscle activity during postural control under optokinetic
stimulation in healthy subjects
Junya Komagata1,2), Atsushi Sugiura1), Hiroshi Takamura2), Yujiro Masu2),
Toshihiro Kitama1)

Center for Life Science Research, University of Yamanashi, Japan, 2Department of
Physical Therapy, Health Science University, Japan1

2P-008

Effects of neonatal dopamine depletion on behavioral responses toanxiogenic tasks in adult rats
Department of Physiology, School of Allied Health Sciences, Kitasato University, Japan

2P-009

Primary motor cortex single cell activity during quadrupedal vs.
bipedal gait in Japanese macaques
Marc A Maier1), Katsumi Nakajima2,3), Kazunori Morita2,3), Akira Murata2),Masahiko Inase2)

1
FR3636, CNRS / Universite Paris Descartes, Sorbonne Paris Cite, France , 2Department of
Physiology, Kindai University, Faculty of Medicine, Japan , 3Department of Physiology,
School of Medicine, Iwate Medical University, Japan

2P-010Features of fine motor skills in 5-year-old children with developmental
coordination disorders
Misaki Mikami1), Shuhei Koeda1), Ayako Osato2), Takahito Masuda3),
Manabu Saito2), Kazuhiko Nakamura2,4), Junko Yamada1)

Hirosaki University Graduate School of Health Sciences, Japan, 2Department of
Neuropsychiatry, Hirosaki University Graduate School of Medicine, Japan, 3Hirosaki
University Faculty of Education, Japan, 4Research Center for Child Mental Development,
Hirosaki University Graduate School of Medicine, Japan1

2P-011

Serotonin-induced synchronization to both respiratory rhythm andbody movement in the pons
Hirotaka Ooka, Chiaki Uchida, Reona Furukawa, Akiko Arata

Department of Physiology, Hyogo College of Medicine, Mukogawa, Japan

2P-012

Neuronal tuning to speed and acceleration of locomotion in mouse
cerebellar cortex
Koji Ikezoe, Kazuo Kitamura

Faculty of Medicine, University of Yamanashi, Japan

2P-013Characteristics of eye movements of 5-year-old children with
developmental coordination disorder
Manabu Saito1,2,4), Shuhei Koeda3), Misaki Mikami3), Taiahiro Aoki5),
Kazutaka Yoshida1), Yui Sakamoto1), Junko Yamada3), Kenji Tsuchiya6),
Taiichi Katayama7), Kazuhiko Nakamura1,2),

Department of Neuropsychiatry, Hirosaki University Graduate School of Medicine,Japan, 2Research Center for Child Mental Development, Hirosaki University Graduate
School of Medicine, Japan, 3Hirosaki University Graduate School of Health Sciences,
Japan, 4Department of Neuropsychiatry, Hirosaki University Hospital, Japan, 5JVCKENWOOD Corporation, Japan, 6Hamamatsu University school of Medicine, japan,
7
Osaka University Graduate School of Medicine, Japan1

2P-014

Postural adjustments associated with transition from quadrupedal tobipedal locomotion in monkeys
Skeletal muscle & locomotion (2)DAY 3Masanori Ogata, Hisanao Akita, Hitoshi Ishibashi

Takashi Suzuki1), You Komagiri1), Kazunori Morita1), Akira Murata2),Masahiko Inase2), Katsumi Nakajima1)
Dept. Physiol., Iwate Med. Univ., Japan, 2Dept. Physiol., Facult. Med., Kindai Univ., Japan1

2P-015Distinctive compositions of nicotinic acetylcholine receptors in slow
and fast muscles
Buntaro Zempo1), Yasuhiro Yamamoto1), Tory Williams2), Fumihito Ono1,2)

Department of Physiology, Division of Life Sciences, Faculty of Medicine, Osaka
Medical College, Japan, 2Laboratory of Molecular Physiology, NIAAA, NIH.

1

2P-016The effects of sensory and cognitive functions on motor coordinationin 5-years old children
Ayako Osato1), Misaki Mikami2), Manabu Saito1), Shuhei Koeda2),
Tamaki Mikami3), Yui Sakamoto1), Kazutaka Yoshida1), Yuri Matsubara1),
Junko Yamada2), Kazuhiko Nakamura1,3),

Department of Neuropsychiatry, Hirosaki University Graduate School of Medicine,Japan, 2Hirosaki University Graduate School of Health Sciences, Japan, 3Research Centerfor Child Mental Development, Hirosaki University Graduate School of Medicine, Japan
1

Exercise (2)2P-017

Habitual physical exercise attenuates classical brown adipose tissue
mass in interscapular region
Junetsu Ogasawara1), Ken Shirato2), Amire Alimu1), Takahiko Yoshida1)

Depertment of Social Medicine, Asahikawa Medical University, School of Medicine,Japan, 2Department of Molecular Predictive Medicine and Sport Science, Kyorin
University, School of Medicine
12P-018Changes in Atf3 and Ankrd2 following denervation induced skeletal
muscle atrophy
Ippei Yamato1), Shuichi Soeda2), Tetsuro Tamaki2)

Department of Medical Education, Tokai University School of Medicine, Japan,
Department of Human Structure and Function, Tokai University School of Medicine

1
2

2P-019Understanding Cardiac Hypertrophy Process After Training withDifferent Intensity In Wistar Rats
Julia Windi Gunadi1), Vita Murniati Tarawan2), Ronny Lesmana2,4),Setiawan Setiawan2), Hanna Goenawan2,4), Teresa Liliana Wargasetia3),
Roro Wahyudianingsih5), Gina Melawati Sukma6), Septo Andry Soesanto6),
Rizky Regia Triseynesya6)

Physiology Department, Faculty of Medicine, Maranatha Christian University,
Indonesia, 2Physiology Division, Basic Medical Science Department, Faculty of Medicine,
Padjadjaran University, 3Biology Department, Faculty of Medicine, Maranatha Christian
University, 4Biological Activity Division, Central Laboratory, Padjadjaran University,
5
Anatomy Pathology, Faculty of Medicine, Maranatha Christian University, 6Faculty of
Medicine, Maranatha Christian University
1

2P-020

Alteration of Autophagy Gene Expression by Different Intensity of
Exercise in Skeletal Muscles
Vita Murniati Tarawan1), Julia Windi Gunadi2), Ronny Lesmana1,5),
Hanna Goenawan1,5), Setiawan Setiawan1), Teresa Liliana Wargasetia3),
Wahyu Widowati3), Yenni Limyati4), Julidea Anggiriani Sipayung6),
Debby Eka Meilina6)

Physiology Division, Basic Medical Science Department, Faculty of Medicine,
Padjadjaran University, Indonesia, 2Physiology Department, Faculty of Medicine,
Maranatha Christian University, 3Biology Department, Faculty of Medicine, Maranatha
1

Skeletal muscle & locomotion (2)/Exercise (2)★ 2P-021(Y-01)

Christian University, 4Physical Medicine and Rehabilitation Department ImmanuelHospital Bandung, 5Biological Activity Division, Central Laboratory, Padjadjaran
University, 6Faculty of Medicine, Maranatha Christian University

Effect of Swimming Exercise to Cardiac PGC-1α and HIF-1α Gene
Expression in Mice
Nova Sylviana1,2), Hanna Goenawan1,2), Ronny Lesmana1,2),
Badai Batara Tiksnadi 3), Hasrayati Agustina4), Bethy S Hernowo4),
Vita Murniati Tarawan1), Unang Supratman2), Ambrosius Purba1),
Setiawan Setiawan1,2)
Department Biomedical Sciences, Faculty Medicine, Padjadjaran University, Bandung,Indonesia , 2Laboratorium Central, Universitas Padjadjaran, Indonesia, 3Department of
Cardiology and Vascular Medicine, Universitas Padjadjaran-Hasan Sadikin Hospital,
Indonesia , 4Department of Pathology Anatomy, Universitas Padjadjaran-Hasan Sadikin
Hospital, Indonesia
1

Influence exercise intensity moderate (walking) delay changes ofphysiology aging for elderly
Gusbakti R1), S Sri Mukti2)

Department Physiology, Faculty of medicine, Universitas Muhammadyah Sumatera
Utara, Indonesia, 2Department Physiology Faculty of Medicine Univ. Gunadarma,Indonesia
1

2P-023

Drastic changes in arterial pressure during high intensity of treadmill
exercise in rats
Kei Tsukioka1), Ko Yamanaka1), Hisashi Naito2), Hidefumi Waki1)

Department of Physiology, Grduate School of Health and Sports Science, Juntendo
University, Japan, 2Department of Exercise Physiology, Grduate School of Health andSports Science, Juntendo University, Japan1

2P-024

Differential improvement of performance by motor imagery of humanankle dorsal and plantar flexion
Nan Liang1,2), Ayumi Tsubota2), Masato Mukai2), Aiko Takezawa2),
Takahiro Masuhara2), Kanji Matsukawa2)

Department of Human Health Sciences, Graduate School of Medicine, Kyoto University,
Japan, 2Department of Integrative Physiology, Graduate School of Biomedical and
Health Sciences, Hiroshima University

1

2P-025The long-term exercise doesn’t affect blood humoral immunity
Kihachiro Fukada1), Hidehiko Kushi2), Terue Takashina1)

Institute of Humanities and Social Sciences, Nihon University, Japan, 2Graduate Schoolof Literature and Social Sciences, Nihon University, Japan1

2P-026

Seasonal effect on resting energy expenditure is age and percent
body fat dependent
Duong Duc Pham, Jeong Hun Lee, Ki Hwan Hong, Youn Joo Jung,
Sung Jin Kim, Chae Hun Leem
Department of Physiology, College of Medicine, University of Ulsan, Korea

2P-027

Exercise Prevents Hypertension by Modulating Sleep-Related
Cardiovascular Autonomic Function in SHRs
Chieh-Wen Chen1,2), Terry B. J. Kuo1,2,3,5,6), Pei-Chi Hsu1), Jai-Yi Li2,7),
Kuan-Liang Kuo4,8), Cheryl C. H. Yang1,2,3,5)

Institute of Brain Science, National Yang-Ming University, Taiwan, 2Sleep ResearchCenter, National Yang-Ming University, Taiwan, 3Brain Research Center, National YangMing University, Taiwan, 4Institute of BioMedical Informatics, National Yang-Ming
University, Taiwan, 5Department of Education and Research, Taipei City Hospital,Taiwan,
6
Graduate Institute of Biomedical Informatics, College of Medical Science and1

Exercise (2)DAY 3

2P-022

Technology, Taipei Medical University, Taiwan, 7Department of Health and LeisureManagement, Yuanpei University of Medical Technology,Taiwan, 8Family Medicine
Department, Taipei City Hospital Ren-Ai Branch, Taiwan

2P-028Does sport discipline at a young age influence the incidence ofhypertension? -J-Fit+studyHiroshi Kumagai1,2), Yuki Someya3,4), Masaki Yoshioka5),
Eri Miyamoto-Mikami1), Youngju Choi6), Yoshimitsu Kohmura1),
Koya Suzuki1), Shuichi Machida1), Hisashi Naito1), Seiji Maeda6),
Noriyuki Fuku1)

1Graduate School of Health and Sports Science, Juntendo University, Japan., 2Research
Fellow of Japanese Society for the Promotion of Science, Japan., 3Department ofMetabolism & Endocrinology, Graduate School of Medicine, Juntendo University,
Japan., 4Sportology Center, Graduate School of Medicine, Juntendo University, Japan.,5
Graduate School of Comprehensive Human Sciences, University of Tsukuba, Japan.,
6
Faculty of Health and Sport Sciences, University of Tsukuba, Japan

2P-029Regular exercise suppresses obesity-associated HCC development
Naoki Takada1), Miho Kumagai2), Tatsuya Ando2,3), Fumitaka Kamachi1,2),
Naoko Ohtani1,2)

Department of Pathophysiology, Osaka City University Graduate School of Medicine,
Department of Applied Biological Science, Faculty of Science and Technology, Tokyo
University of Science, 3Division of Clinical Laboratory, Gifu University, School of
Medicine

1
2

2P-030Lower urinary tract symptoms are associated with reduced peak
aerobic capacity in old people
Yu Takeda1), Shizue Masuki1,2), Mayuko Morikawa1,2,3), Hiroshi Nose3)

Department of Sports Medical Sciences, Shinshu University Graduate School of
Medicine, 2Institute for Biomedical Sciences, Shinshu University, 3Jukunen Taiikudaigaku
Research Center

1

2P-031

Assessment of thermal load during exercise in junior high school
students using wearable sensors
Issei Kato, Kei Nagashima, Shuri Marui, Yuta Masuda★ 2P-032(Y-02)

Department of Human science, University of waseda, Japan

Respiratory Muscle Training (RMT), Aerobic Fitness and Perform­
ance in Sri Lankan Rowers
Dilani Priyashanthi Perera1), Anoja Ariyasinghe2), Anula Kariyawasam2)
Department of Physiotherapy, Faculty of Allied Health Sciences, General Sir John
Kotelawala Defence University, Sri Lanka, 2Department of Physiology, Faculty of
Medicine, University of Peradeniya, Sri Lanka

1

2P-033The expression and distribution of mitsugumin53 in skeletal muscle
after lengthening contraction
Yuhei Hibino1), Yuki Katanosaka2), Kimiaki Katanosaka1)

1
Department of Life and Health Science, Chubu University, Japan , 2Department of
Cardiovascular Physiology, Graduate School of Medicine, Dentistry and Pharmaceutical
Sciences, Okayama University, Japan

2P-034

Neuroendocrine response to long-term exercise

Terue Takashina1), Hidehiko Kushi2), Kihachiro Fukada1)
Institute of Humanities and Social Sciences, Nihon University, Japan, 2Graduate Schoolof Literature and Social Sciences, Nihon University, Japan1

2P-035

The relationship of body mass index and aerobic capacity in primaryschool students in Jakarta
Exercise (2)Nurul Paramita, Sophie Yolanda, Imelda Rosalyn Sianipar,
Dewi Irawati Soeria Santoso
Department of Medical Physiology, Universitas Indonesia, Indonesia

2P-036

The analgesic effect of voluntary running in a rat model of persistent
inflammatory pain
Risa Yamauchi1,2), Hideshi Ikemoto1), Takayuki Okumo1,3), Nachi Ebihara1),
Mana Tsukada1), Hiroyuki Horikawa1,2), Shi-Yu Guo1), Yan-Qing Liu1,4),
Tadashi Hisamitsu1), Masataka Sunagawa1),

2P-037A Randomised Controlled Trial Evaluating Effect of Walking Advice
on Improving Depressive Symptoms
Mei-Yuk Lam, Ka-Tik Cheung

School of Medical and Health Sciences, Tung Wah College, China

2P-038

Acute effects of mechanical compression in hypoxia on arterial
stiffness
Masato Nishiwaki★ 2P-039(Y-03)

Faculty of Engineering, Osaka Institute of Technology, Japan

Factors affecting oxygen pulse in a healthy Thai population
Tichanon Promsrisuk, Napatr Sriraksa, Ratchaniporn Kongsui
Division of Physiology, School of Medical Sciences, University of Phayao, Thailand

2P-040Circulatory dynamics and autonomic nervous activities between
sprinters and distance runners
Xinru Sun1), Madoka Nozawa1), Sayaka Saito1), Junko Hoshi1),
Hiromasa Tanno1), Emi Kanno1), Ryoko Maruyama1)

Department of Health Sciences, Tohoku University Graduate School of Medicine,
Japan

1

2P-041

Exercise habit is correlated to lower fall risks among elderly people
living in urban areas
Hisayo Yokoyama1), Hitoshi Watanabe1), Kazumi Saito2), Ayane Shibata2),
Yuta Suzuki1), Daiki Imai1), Kazunobu Okazaki1), Akira Ogita1)

1
Research Center for Urban Health and Sports, Osaka City University, Japan, 2Social
Welfare Bureau, Osaka City

2P-042

Asymmetry of plantar flexor muscle but not Achilles tendon in highjumpers

Keigo Tomoo, Tadashi Suga, Yusuke Izui, Hiromasa Ueno, Masafumi Terada,
Akinori Nagano, Tadao Isaka
Depoartment of Sports and Health Science, Ritsumeikan University, Japan

Circulation & Respiration: Cardiac Physiology (2)2P-043nNOS regulation of myocyte contraction and [Ca2+]i handling withfatty acid supplementation
Yin Hua Zhang

Department of Physiology, Seoul National University, College of Medicine, Korea

Exercise (2)/Circulation & Respiration: Cardiac Physiology (2)

DAY 3

1
Department of Physiology, School of Medicine, Showa University, Japan, 2Faculty ofArts and Sciences at Fujiyoshida, Showa University, Japan, 3Department of Orthopaedic
Surgery, Showa University Fujigaoka Hospital, Japan, 4Department of Combined
Traditional Chinese and Western Medicine, Yangzhou University School of Medicine,China2P-044

A novel superforated-patch technique revealed the Ca2+-triggeredarrhythmogenesis from the T-tubules
Takao Shioya

Department of Physiology, Faculty of Medicine, Saga University, Japan

2P-045

Propagation of repolarization induced in a cell array of human ventricular cell models
Shotaro Kiyokawa, Natsuki Yamamoto, Akinori Noma, Akira Amano

Department of Bioinfomatics, Graduation school of Lifescience,
Ritsumeikan, Japan

2P-046

University of

Screening for novel RyR2 inhibitor by ER Ca2+ monitoring

Mai Tamura1), Nagomi Kurebayashi1), Takashi Murayama1), Shuichi Mori2),
Mari Ishigami-Yuasa2), Hiroyuki Kagechika2), Junji Suzuki3),
Kazunori Kanemaru4), Masamistu Iino4), Takashi Sakurai1),
1Dept Pharmacol, Fac Med, Juntendo Univ, Japan, 2Tokyo Med Dent Univ, Japan, 3Univ
California San Francisco, USA, 4Nihon Univ Sch Med, Japan

2P-047

Molecular architecture of catecholamine-induced arrhythmogenicity
in rat pulmonary vein
Yosuke Okamoto1), Naing Ye Aung2), Yoshinobu Nagasawa3), Daichi Takagi1),
Kyoichi Ono1)

Department of cell physiology, Akita University Graduate School of Medicine, Japan,
Pathological and Image analysis center, Cancer Research center, Yamagata University
Faculty of Medicine, 3Department of Pharmacology and Therapeutics, Faculty of
Pharmaceutical Sciences, Toho University
1
2

2P-048High throughout screening of RyR2 inhibitors as candidates for novelantiarrhythmic drugs
Masatoshi Ito1), Nagomi Kurebayashi1), Takashi Murayama1), Mai Tamura1),
Mari Ishigami- Yuasa2), Shuichi Mori2), Hiroyuki Kagechika2), Junji Suzuki3),
Kazunori Kanemaru4), Masamitsu Iino4), Takashi Sakurai1)

Dept Pharmacol, Fac Med, Juntendo Univ, Tokyo, Japan, 2Tokyo Med Dent Univ, Japan,
Univ Calfornia, USA, 4Nihon Univ Sch Med, Japan1
3

2P-049Anti-arrhythmic force of leak current enhancement in manufactured
atrial fibrillation of rat
Kako Andoh, Yoriko Katoh, Yosuke Okamoto, Yui Takahashi, Daichi Takagi,
Kyoichi Ono
Department of Cell Physiology, Akita Graduate School of Medicine, Japan

2P-050Interventricular difference in calcium sensitivity with lower expressionof calcium binding proteins
Young Keul Jeon1,2,3), Ji Hyun Jang1,2,3), Juhan Woo1,2,3), Hae Jin Kim1,2,3),
Su Han Cho1,2,3), Yin Hua Zhang1,2,3), Sung Joon Kim1,2,3)

Department of Physiology, Seoul National University, College of Medicine, Republic ofKorea, 2Department of Biomedical Sciences, Seoul National University, College ofMedicine, Republic of Korea, 3Ischemic/Hypoxic Disease Institute, Seoul National
University College of Medicine, Republic of Korea
1★★2P-051(Y-04)

Mitochondrial fusion promoter attenuates left ventricular dysfunctionin pre-diabetic rats
Chayodom Maneechote1,2,3), Siripong Palee1,2,3), Nattayaporn Apaijai1,2,3),
Thidarat Jaiwongkam1,2,3), Sasiwan Kerdphoo1,2,3),
Siriporn C Chattipakorn1,2,4), Nipon Chattipakorn1,2,3)
Circulation & Respiration: Cardiac Physiology (2)Cardiac Electrophysiology Research and Training Center, Faculty of Medicine, Chiang
Mai University, Thailand, 2Center of Excellence in Cardiac Electrophysiology Research,
Chiang Mai University, Thailand, 3Cardiac Electrophysiology Unit, Department of
Physiology, Faculty of Medicine, Chiang Mai University, Thailand, 4Department of Oral
Biology and Diagnostic Sciences, Faculty of Dentistry, Chiang Mai University, Thailand
1

2P-053The use of fetal heart rate variability to identify evolving brain injury
after asphyxia
Kyohei Yamaguchi1), Christopher Arther Lear2), Alistair Jan Gunn2),
Tomoaki Ikeda1), Laura Bennet2), Yoshiki Maeda1)

Department of Obstetrics & Gynecology, Mie University Faculty of Medicine, Japan,
The Fetal Physiology and Neuroscience Group, Department of Physiology, The
University of Auckland, New Zealand

12

Generation mechanism of transient EAD in a mathematical ventricular
model
Yuichiro Ito, Hiroyuki Kitajima, Toru Yazawa

Department of Engineering and Design, Kagawa University, Japan

2P-055

Alternans in a Mathematical Crustacean Cardiac Model
Hiroyuki Kitajima, Toru Yazawa

Department of Engineering and Design, Kagawa University, Japan

2P-056

Dynamical mechanisms of phase-2 early afterdepolarizations inhuman ventricular myocyte models
Yasutaka Kurata1), Kunichika Tsumoto1), Mamoru Tanida1), Yuhichi Kuda1),
Ichiro Hisatome2)

1
Department of Physiology II, Kanazawa Medical University, Japan, 2Division ofRegenerative Medicine and Therapeutics, Institute of Regenerative Medicine andBiofunction, Tottori University Graduate School of Medical Science

2P-057

Mechanisms of L-type Ca2+ channel blockers to produce EAD in
drug-induced arrhythmia
Shingo Murakami, Akira Kimura

Department of Electrical, Electronic, and Communication Engineering, Faculty of
Science and Engineering, Chuo University , Japan★★2P-058(Y-05)

Crossbridge thermodynamics in right heart failure

June-Chiew Han1), Toan Pham1), Kenneth Tran1), Andrew J. Taberner1,2),
Denis S. Loiselle1,3)123★★2P-059(Y-06)

Auckland Bioengineering Institute, The University of Auckland, New Zealand,
Department of Engineering Science, The University of Auckland, New Zealand,
Department of Physiology, The University of Auckland, New Zealand

LysoPC plays a crucial role in cholesterol-induced nonobese MS cardiomyopathy
Jiung-Pang Huang, Li-Man Hung

Department of Biomedical Sciences, Chang Gung University,Taiwan

2P-060

Successful establishment of a murine model of cardiac reverse remodeling
Tatsuyuki Sato1), Norihiko Takeda1), Yu Nakagama2), Masaki Wake1),
Katsura Soma1), Hiroaki Semba1), Takayuki Isagawa3), Issei Komuro1)

Department of Cardiovascular Medicine, University of Tokyo Graduate School of
Medicine, Japan, 2Department of Pediatrics, University of Tokyo Graduate School of
Medicine, Japan, 3Department of Cardiovascular Medicine, Nagasaki University
Graduate School of Biomedical Sciences, Japan1

Circulation & Respiration: Cardiac Physiology (2)DAY 3

2P-054

2P-062

Forced expression of DFCP1 attenuates cardiac fibroblasts acti­
vation via promoting autophagic flux
Xiaojing Liu1,2)

1
Laboratory of Cardiovascular Diseases, University of Sichuan, China, 2Department of
Cardiology, University of Sichuan, China

2P-063Chronic isoproterenol stimulation induced different cardiac disordersin Tric-deficient mice
Daiju Yamazaki

Division of Pharmacology, National Institute of Health Sciences, Japan

2P-064

SDH deficiency induced metabolic switch and dilated cardio­myopathy
Wenwen Li, Xianhua Wang, Heping Cheng, Qi Ma
Peking University, China

2P-065Chronic response of renal and lumbar sympathetic nerve activity to
myocardial infarction in rats
Misa Yoshimoto, Shizuka Ikegame, Fumi Hyodo, Yuki Shiwa, Kenju Miki★ 2P-066(Y-07)

Department of Health Science, University of Nara women's University, Japan

Inhibition of p16 INK4a protects against myocardial ischemia/
reperfusion injury
Zhou Qiulian, Bei Yihua, Meng Xiangmin, Xiao Junjie
Institute of Cardiovascular Sciences, School of Life Science, Shanghai University, China

2P-067The cytotoxic effect of 2-APB in H9c2 cells
YanCheng Shen1), KunTa Yang2,3)

Department of Pharmacology and Toxicology, School of Medicine, Tzu Chi University,
Taiwan, 2Department of Physiology, School of Medicine, Tzu Chi University, Taiwan ,3
Institute of Medical Sciences, Tzu Chi University, Taiwan
1

2P-068

Protective Effect of Intermittent Hypoxia Against Oxidative Stress
Injury in Rat Cardiomyocytes
I-Chieh Wang1), Chih-Feng Lien2), Kun-Ta Yang3)

1
PhD Program in Pharmacology and Toxicology, Tzi Chi University, Taiwan, 2Institute ofMedical Sciences, Tzu Chi University, Taiwan, 3Department of Physiology, School of
Medicine, Tzu Chi University, Taiwan

2P-070The cardiac end-systolic pressure-volume (force-length) relation iscontraction-mode dependent
Kenneth Tran1), Toan Pham1,2), Andrew J Taberner1,3), Denis S Loiselle1,2),
June-Chiew Han1)

1
Auckland Bioengineering Institute, University of Auckland, New Zealand, 2Departmentof Physiology, University of Auckland, New Zealand, 3Department of Engineering
Science, University of Auckland, New Zealand

2P-071Glycolytic pathway is activated in rat embryonic heart just after the
beginning of the heartbeat
Tatsuya Sato1,2), Nobutoshi Ichise1), Takeshi Kobayashi1), Hiroya Yamazaki1),
Yoshinori Terashima1), Shunsuke Jimbo1), Noritsugu Tohse1)

Department of Cellular Physiology and Signal Transduction, Sapporo Medical
university School of Medicine, Japan, 2Department of Cardiovascular, Renal, andMetabolic Medicines, Sapporo Medical university School of Medicine, Japan1

2P-072

Rapid heating induces high-frequency sarcomeric oscillations inliving rat neonatal cardiomyocytes
Circulation & Respiration: Cardiac Physiology (2)Seine A. Shintani1), Kotaro Oyama2,3), Shin’Ichi Ishiwata4), Norio Fukuda5)
Department of Biomedical Sciences, College of Life and Health Sciences, The Chubu
University, Japan, 2Quantum Beam Science Research Directorate, National Institutes for
Quantum and Radiological Science and Technology, Japan, 3PRESTO, Japan Scienceand Technology Agency, Japan, 4Department of Physics, Faculty of Science andEngineering, Waseda University, 5Department of Cell Physiology, The Jikei University
School of Medicine, Japan1

2P-073

Roles of Epac1 in the regulation of contractility in cardiac muscle
Yoshiki Ohnuki, Kenji Suita, Satoshi Okumura

Department of Physiology, Tsurumi University School of Dental Medicine, Japan

2P-074

In vivo nano-analysis of the dynamics of individual sarcomeres in thebeating mouse heart
Department of Cell Physiology, The Jikei University School of Medicine, Japan,
National Institutes for Quantum and Radiological Science and Technology, 3PRESTO,
Japan Science and Technology Agency, 4Technical Division, School of Science, The
University of Tokyo, 5Department of Physics, Faculty of Science and Engineering,
Waseda University
1
2

2P-075

Role of pannexin hemichannel on stretch-induced mitochondrial
hyperpolarization in cardiomyocytes
Daisuke Katsura1), Gentaro Iribe1), Keiko Kaihara1), Keiji Naruse1)
1

2P-076

Department of Cardiovascular Physiology, Okayama University, Japan

Comparison of cardiomyocyte kinetics of rat left ventricle and turtle
ventricle
Yoshihiro Ujihara1,2), Akira Hanashima2), Takeshi Honda2), Aya Kodama2),
Ken Hashimoto2), Satoshi Mohri2)

Department of Electrical and Mechanical Engineering, Nagoya Institute of Technology,
Japan, 2First department of Physiology, Kawasaki Medical School, Japan1

2P-077

Hydrogen Sulfide Exerts Cardioprotection in Sepsis by Inhibiting
Endoplasmic Reticulum Stress
Yuming Wu1,4,5), Yuhong Chen1,2), Sheng Jin1), Xu Teng1), Zhenjie Hu2),
Xuan Qiu3)

1
Department of Physiology, Hebei Medical University, China, 2Intensive care unit, The
Fourth Hospital of Hebei Medical University, China, 3Department of endocrinology, The
Third Hospital of Hebei Medical University, China, 4Hebei Collaborative Innovation
Center for Cardio-Cerebrovascular Disease, China, 5Key Laboratory of Vascular Medicineof Hebei Province, China

2P-078

Physiological Studies on the Protective Effect Ofmelatonin against
Doxorubicin Cardiotoxicity
Faten Mahmoud Diab

Physiology Department, Faculty of Medicine, Ain Shams University, Egypt

2P-079Optogenetic cardiac pacing in freely-moving mice

Jun Kaminosono1), Yuki Kambe2), Tomoyuki Kuwaki1), Akira Yamashita1)
Dept. Physiol.1, Grad. Sch. Med. Dent. Sci., Kagoshima Univ., Japan, 2Dept. Pharmacol.,Grad. Sch. Med. Dent. Sci., Kagoshima Univ., Japan1

2P-080The prevalence of low physical activity and its association with otherrisk factors in Iran
Majid Askaripour1), Masoomeh Kahnooji2), Mahboobeh Yeganeh2),
Fatemeh Tavakoli3), Mitra Shadkam4), Farzaneh Rostamzadeh1),
Circulation & Respiration: Cardiac Physiology (2)DAY 3Fuyu Kobirumaki-Shimozawa1), Kotaro Oyama2,3), Togo Shimozawa4),
Shin’Ichi Ishiwata5), Norio Fukuda1)

Hamid Najafipour2)
Physiology Research Center, Institute of Basic and Clinical Physiology Sciences andDepartment of Physiology and Pharmacology Kerman University of Medical Sciences,
Kerman, Iran, 2Cardiovascular Research Center, Institute of Basic and Clinical Physiology
Sciences and Shafa hospital, Kerman University of Medical Sciences, Iran, 3Departmentof Biostatistics and Epidemiology, Kerman University of Medical Sciences, Iran ,4
Endocrinology and Metabolism Research Center, Institute of Basic and ClinicalPhysiology sciences, Kerman University of Medical Sciences, Iran1

2P-081Development of light-controllable nitric oxide releasing small compounds and biological application
Naoya Ieda, Hana Okuno, Ayaka Yamauchi, Yuji Hotta,
Mitsuyasu Kawaguchi, Kazunori Kimura, Hidehiko Nakagawa

Graduate School of Pharmaceutical Sciences, Nagoya City University, Japan

Circulation & Respiration: Lung Physiology (2)2P-082

Airway epithelial integrin β4 expression deficiency leads to lungdysplasia in mice
Yang Xiang1), Yu Chen1,2), Wang Jiang1), Di Wu1), Jinmei Wang1), Chi Liu1),
Xiaoqun Qin1)

Department of Physiology, Xiangya School of Medicine, Central South University,
China, 2Department of laboratory medicine, Hunan Normal University of
medicine, China
1

2P-083

S1P2 aggravates lung fibrosis through altering alveolar macrophage
polarization in miceYasuo Okamoto1,2), Juanjuan Zhao1), Kazuaki Yoshioka1), Sho Aki1),
Kazuhiro Ishimaru1), Noriko Takuwa1,3), Yoh Takuwa1)

1
Dept. of Physiology, Kanazawa Univ. Sch. Med., Japan, 2Dept. of Pharmacology,
Kawasaki Medical School, 3Dept. of Health & Med. Sci., Nursing Univ.

2P-084Lung Functions and Feno Levels during Phases of Menstrual Cyclein Asthmatic and Healthy Females
Kushani Rasangika Atukorala1), Sharaine Fernando1), Nalinda Silva1),
Lakmali Amarasiri2)

Department of Physiology, Faculty of Medical Sciences, University of SriJayewardenepura, Sri Lanka, 2Department of Physiology, Faculty of Medicine, Universityof Colombo
1

2P-085

The role of miR-126 on LPS-induced acute lung injury in mice
Yongsheng Gong, Haizeng Zhang, Danyang Chen, Qiuyun Tian,
Sunzhong Mao, Xiaofang Fan, Shufang Liu

Institute of Hypoxia Medicine,School of Basic Medical Sciences,Wenzhou Medical
University, China

2P-086Chloramphenicol induces autophagy and inhibits the HIF1α pathway
in NSCLC cells
Ching-Hao Li1), Po-Lin Liao2), Yu-Wen Cheng3), Shih-Hsuan Huang3),
Han-Lin Hsu4), Jaw-Jou Kang2)

Department of Physiology, School of Medicine, College of Medicine, Taipei Medical
University, Taiwan, 2Institute of Food Safety and Health Risk Assessment, School of
Pharmaceutical Sciences, National Yang-Ming University, Taiwan, 3College of Pharmacy,
Taipei Medical University, Taiwan, 4Division of Pulmonary Medicine, Department ofInternal Medicine, Taipei Medical University-Wan Fang Hospital, Taiwan
1

Circulation & Respiration: Cardiac Physiology (2)/Circulation & Respiration: Lung Physiology (2)★ 2P-087(Y-09)

Circulation & Respiration: Vascular Physiology (2)Influence of Tobacco smoking on carboxyhaemglobin levels andblood lipid levels
Prasanna Herath1), Savithri Wimalasekera2), Thamara Amarasekara3)
Department of Nursing and Midwifery, Faculty of Allied Health Sciences , General Sir
John Kotelawala Defence University, Sri Lanka, 2Department of Physiology, Faculty of
Medical Sciences, University of Sri Jayewardenepura, Sri Lanka, 3Department of Allied
Health Sciences, Faculty of Medical Sciences, University of Sri Jayewardenepura, Sri
Lanka
1

2P-088Stimulation of nitric oxide production in vascular endothelial cells byRaphanus sativus extract
Department of Biochemical Science & Technology, Graduate School of Agriculture,
Kagoshima University, Japan, 2Central Research Laboratory, Hamamatsu Photonics K.K.,
Japan, 3Department of Food Science & Biotechnology, Faculty of Agriculture,
Kagoshima University, Japan1

2P-089The vasodilatory effect of Tiliacorinine 12′-O-acetate in rat aorta
Luckika Panthiya1), Jiraporn Tocharus2), Rungusa Pantan1),
Archawin Nakaew3), Apichart Suksamrarn3), Chainarong Tocharus1)

Department of Anatomy, Faculty of Medicine, Chiang Mai University, Thailand,
Department of Physiology, Faculty of Medicine, Chiang Mai University, Thailand,
3
Department of Chemistry and Center of Excellence for Innovation in Chemistry,
Faculty of Science, Ramkhamhaeng University, Thailand
12

2P-090Effects of adiponectin against CoCl2induced apoptosis of SMCs via
HIF-1α/cAMP/PKA/Cx43 pathway
Jingjie Xiao1,2), Wei Zhang1,3), Lei Wu1,4), Liang Zhang1,2), Yang Wang1,2),
Li Li1,2), Junqiang Si1,2), Xinzhi Li1,5), Ketao Ma1,2)

Key Laboratory of Xinjiang Endemic and Ethnic Diseases, Medicine School of Shihezi
University, China, 2Department of Physiology Medicine School of Shihezi University
Shihezi, China, 3Department of Gerontology, the First Affiliated Hospital, Medicine
School of Shihezi University, China, 4Department of Cardiology, the First AffiliatedHospital, Medicine School of Shihezi University, Shihezi, China, 5Department of
Pathophysiology, Medicine School of Shihezi University, Shihezi, China
1

2P-091

Hemodynamic responses to hyperbaric treatment in skeletal muscle
of obesity and type 2 diabetes rats
Natsuki Goto1), Naoto Fujita1), Ryosuke Ochi1), Wataru Nino1),
Kazuyoshi Hisatsune1), Hisao Nishijo2), Susumu Urakawa1)

Dept of Musculoskeletal Functional Research and Regeneration, Grad. Sch. of
Biomedical & Health Sciences, Hiroshima Univ., Japan, 2Dept. of System Emotional
Science, Grad. Sch. of Medical and Pharmaceutical Science, Univ. of Toyama, Japan1

2P-092Differential changes of flow-induced vasodilation mechanisms incoronary arteries from SHR and WKY
Suhan Cho, Hae Jin Kim, Ming Zhe Yin, Sung Joon Kim

Department of Physiology, Seoul National University College of Medicine, Korea

2P-093

Measurement of pulmonary arterial capacitance in the pathogenesisof pulmonary hypertension in rats
Hirotsugu Tsuchimochi1), Ryohei Fukuba1,2), Takashi Sonobe1),
Shigeki Taniguchi2), James T Pearson1,3)
1

Department of Cardiac Physiology, National Cerebral and Cardiovascular Research
Circulation & Respiration: Vascular Physiology (2)DAY 3Misato Wakamatsu1), Rei Kuroda1), Kimiko Kazumura2), Yuji Minami3),
Katsuko Kajiya3)

Center, Japan, 2Department of Thoracic and Cardiovascular Surgery, Nara Medical
University School of Medicine, Japan, 3Department of Physiology, Monash University,
Australia

2P-094

Advanced method for vessel identification and assessment ofconcurrent dynamic vascular events
Naoki Honkura1,2), Mark Richerds2), Tetsumei Urano1),
Lena Claesson-Welsh2)

Department of Medical Physiology, Hamamatsu University school of Medicine, Japan,
Department of Immunology, Genetics and Pathology, Rudbeck Laboratory, Uppsala
University, Sweden

12

2P-095

Resveratrol stimulates Na+-Ca2+exchanger to reduce cytosolic Ca2+in
rat aortic smooth muscle cells
Yunting Zhang1), F Yan2), Xiaoqiang Yao1)
1
2

2P-096

Department of Biomedical Sciences, The Chinese University of Hong Kong, China,
Department of Physiology, Guangzhou University of Chinese Medicine, China

The involvement of calpain in abnormal vascular smooth muscle
contraction induced by SPC and U46619
Hiroko Kishi1), Qian Lu1), Tomoka Morita1), Ying Zhang1), Bochao Lyu1),
Min Zhang1), Nan Li1), Sei Kobayashi1)

Department of Molecular and Cellular Physiology, Yamaguchi University Graduate
School of Medicine, Japan1

2P-097

Effects of Capsaiciniod Nonivamide on Obesity-Related Vascular
Dysfunction in Obese Rat
Sivanan Sivasinprasasn1), Naruemon Wikan1), Apichart Suksamrarn 2),
Jiraporn Tocharus 3), Chainarong Tocharus 1)

Department of Anatomy, Faculty of medicine, Chiang Mai University, Thailand,
Department of Chemistry and Center of Excellence for Innovation in Chemistry,
Faculty of Science, Ramkhamhaeng University, Thailand, 3Department of Physiology,
Faculty of Medicine, Chiang Mai University, Thailand
12

2P-098

Deficiency of HIF2α in VSMCs Protects Against Angiotensin IIInduced Abdominal Aortic Aneurysm
Yanting Song1), Dan Qi1), Xia Wang1), Ye Liu1), Huihua Li1,2), Jie Du2,3),
Aijuan Qu1,2)

Department of Physiology and Pathophysiology, School of Basic Medical Sciences,
Capital Medical University, China, 2Key Laboratory of Remodeling-Related
Cardiovascular Diseases, Ministry of Education, 3Beijing Anzhen Hospital of Capital
Medical University and Beijing Institute of Heart Lung and Blood Vessel Diseases, China
1

2P-099Intermedin reduces neointima formation by regulating vascularsmooth muscle cell phenotype
Yong Fen Qi, Qing Zhu, Xian-Qiang Ni, Wei-Wei Lu, Jin-Sheng Zhang,
Jin-Ling Ren, Di Wu, Yao Chen, Lin-Shuang Zhang, Yan-Rong Yu,
Chao-Shu Tang
Peking University Health Science Center, China

2P-100Role of mitochondrial phosphate transporters in vascular calcification
Nhung Thi Nguyen, Tuyet Thi Nguyen, Soo-Jin Kim, Luong Dai Ly,
Dat Da Ly, Seung-Kuy Cha, Kyu-Sang Park

Department of Physiology, Wonju College of Medicine, Yonsei University, Korea

2P-101

Evolutional relationship between hearts and elastic protein connectins
Akira Hanashima, Yoshihiro Ujihara, Mayuko Tada, Mai Iwasa, Aya Kodama,
Circulation & Respiration: Vascular Physiology (2)Takeshi Honda, Ken Hashimoto, Satoshi MohriFirst Department of Physiology, Kawasaki Medical school

2P-102

Changes in the Right Coronary Microvascular Function in Pulmonary
Arterial Hypertension
Mark T Waddingham1), Huiling Jin2), Takashi Sonobe2),
Hirotsugu Tsuchimochi 2), Ryotaro Asano1), Keiji Umetani3),
Mikiyasu Shirai1), Takeshi Ogo1), James T Pearson 2)

Department of Advanced Medical Research for Pulmonary Hypertension, National
Cerebral and Cardiovascular Center Research Institute, Japan, 2Department of Cardiac
Physiology, National Cerebral and Cardiovascular Center Research Institute, Japan,
3
Japan Synchrotron Radiation Research Institute, Japan1

2P-103Sung Eun Kim1,2), Ming Zhe Yin1,2), Hae Jin Kim1), Yin Hua Zhang1,2,3),
Sung Joon Kim1,2,3)

1
Department of physiology, Seoul National University College of Medicine, 2Departmentof Biomedical Sciences, Seoul National University College of Medicine, 3Ischemic/
Hypoxic Disease Institute Seoul National University College of Medicine★★2P-104(Y-10)FUNDC2 regulates platelet activation through AKT/GSK-3β/cGMP
axis
Qi Ma1), Weilin Zhang2), Heping Cheng1), Junling Liu3), Quan Chen2)

1Institute of Molecular Medicine, Peking University, China, 2Institute of Zoology, Chinese
Academy of Sciences, Beijing, China, 3School of Medicine, Shanghai Jiao Tong University,
China

2P-105

A Mathematical Model of Cardiac Cycle Driven by the Human Ventricular Cell Model
Sayaka Niwa1), Yukiko Himeno2), Akinori Noma2), Akira Amano2)

Bioinformatics course, Graduate School of Life Sciences, Ritsumeikan University, Japan,
Department of Bioinformatics, College of Life Sciences, Ritsumeikan University, Japan1
2

2P-106

Atypical antipsychotic drug olanzapine leads to aggravation ofatherosclerosis in apoE-null miceChia-Hui Chen1), Song-Kun Shyue2), Chiao-Po Hsu3,4), Tzong-Shyuan Lee1,5)Department of Physiology, School of Medicine, National Yang-Ming University,Taiwan,
Cardiovascular Division, Institute of Biomedical Sciences, Academia Sinica, Taiwan,
3
Division of Cardiovascular Surgery, Department of Surgery, Taipei Veterans General
Hospital, Taiwan, 4Faculty of Medicine, School of Medicine, National Yang-Ming
University, Taipei, Taiwan; 5Graduate Institute and Department of Physiology, College ofMedicine, National Taiwan University, Taiwan, 5Graduate Institute and Department of
Physiology, College of Medicine, National Taiwan University, Taiwan
12

2P-107

Effect of Total Cholesterol on Blood Pressure and the Difference
between Genders
Reza Ishak Estiko, Miranti Dewi Pramaningtyas

Faculty of Medicine, Universtas Islam Indonesia, Indonesia

2P-108The prevalence of hypertension and incidence in Southeastern Iran:
A Community-based Study
Soodeh Rajabi1), HamidReza Nasri2), Farzaneh Rostamzadeh3),
Freidoon Jahangir4), Mahboobeh Yeganeh-Hajahmadi1), Mitra Shadkam5),
Hamid Ajafipour2)

Physiology Research Center, Institute of Basic and Clinical Physiology Sciences, andDepartment of Physiology and Pharmacology, Kerman University of Medical Sciences,

1

Circulation & Respiration: Vascular Physiology (2)DAY 3

Decreased Kir and Kv of right coronary artery SMC in pulmonary
arterial hypertensive rats

Iran, 2Cardiovascular Research Center, Institute of Neuropharmacology and Departmentof Physiology and Pharmacology, Kerman University of Medical Sciences, Iran,
3
Endocrinology and Metabolism Research Center, Institute of Basic and ClinicalPhysiology Sciences and Department of Physiology and pharmacology, Kerman
University of Medical Sciences, Iran, 4Department of Biostatistics and Epidemiology,
Kerman University of Medical Sciences, Iran, 5Gasteroentrology and Hepathology
Research Center, Institute of Basic and Clinical Physiology Sciences, Kerman Universityof Medical Sciences, Iran★ 2P-110(Y-11)

Endocrine, Reproduction & Development (2)Genistein and running exercise modulates HDAC3 and the fibrosis
markers in OVX rats with NASH
Namthip Witayavanitkul1), Duangporn Werawatganon1),
Naruemon Klaikeaw2), Prasong Siriviriyakul1)
1
2

2P-111

Department of Physiology, Faculty of Medicine, Chulalongkorn University, Thailand,
Department of Pathology, Faculty of Medicine, Chulalongkorn University, Thailand

DHA Protects Against Hepatic Steatosis by Activating Sirt1 in
Nonalcoholic Fatty Liver Disease Mice
Xiao Luo1,2), Xinqian Gu2,3), Xiaomin Su2,3), Xin Liu4), Zhangya He2,3),
Xiaomin Li2,3), Ru Jia5), Bei Han2,3), Yan Yu2,3), Xiaoqin Luo2,3),

Department of Physiology and Pathophysiology, School of Basic Medical Sciences,
Xi'an Jiaotong University Health Science Center, China, 2Department of Nutrition andFood Safety, School of Public Health, Xi’an Jiaotong University, China, 3Nutrition andFood Safety Engineering Research Center of Shaanxi Province, School of Medicine,
Xi’an Jiaotong University, China, 4Department of Epidemiology and Health Statistics,
School of Public Health, Xi'an Jiaotong University, China, 5Department of Prosthodontics,
Stomatological Hospital, College of Stomatology, Xi’an Jiaotong University, China
1

2P-112

Neurosecretory protein GL, a hypothalamic small protein, regulates
appetite and energy homeostasis
Kenshiro Shikano1,2), Daichi Matsuura2), Takaya Saito2),
Eiko Iwakoshi-Ukena2), Megumi Furumitsu2), Kazuyoshi Ukena2)

1
Department of Neurophysiology, Faculty of Medicine, Oita University, Japan, 2Sectionof Behavioral Sciences, Graduate School of Integrated Arts and Sciences, Hiroshima
University, Japan

2P-113

Effect of long term high-fat diet and calorie restriction on the hepatic
NAD metabolism in mice
Xiaojing Wei1), Ru Jia2), Qiqi Wang1), Jiaqi Huang1), Xiao Luo1), Jianqun Yan1)

Department of Physiology and Pathophysiology, School of Basic Medical Sciences,
Xi'an Jiaotong University Health Science Center, China, 2Department of Prosthodontics,
College of Stomatology, Stomatological Hospital, Xi’an Jiaotong University, China
1

2P-114

Effect of flaxseed on a inflammatory response in patients with hypercholesterolemia-preliminary data
Dominika Kanikowska1), Rafał Rutkowski1), Krzysztof Pawlaczyk2),
Maki Sato3), Monika Misian2), Andrzej Bręborowicz1), Janusz Witowski1)

Department of Pathophysiology, Poznan University of Medical Sciences, Poland,
Department of Nephrology, Transplantology, and Internal Medicine, Poznan Universityof Medical Sciences, Poland, 3Department of Physiology, Aichi Medical University,
Japan

1
2

2P-115The hypothalamic feeding-related neuropeptides in the streptozotocininduced diabetic rat
Satomi Sonoda1,2), Kenya Sanada1), Hiroki Beppu1), Kazuaki Nishimura1),

Circulation & Respiration: Lung Physiology (2)/Endocrine, Reproduction & Development (2)Haruki Nishimura1), Kentaro Tanaka1), Hiromichi Ueno1),
Mitsuhiro Yoshimura1), Takashi Maruyama1), Yoshiya Tanaka2), Yoichi Ueta1)
Department of Physiology, School of Medicine, University of Occupational andEnvironmental Health, Japan, 2The First Department of Internal Medicine, School of
Medicine, University of Occupational and Enviromental Heatlth, Japan1

2P-116

Effects of estradiol on an orexigenic function of ghrelin in ovariecto­
mized rats fed high-fat diet
Naoko Yokota-Nakagi1,2), Mizuho Kawakami1), Haruka Takahashi1),
Akira Takamata1), Yuki Uchida1), Keiko Morimoto1)

Department of Environmental Health, Faculty of Life Science and Human Technology,
Nara Womens University, Japan, 2Department of Health and Nutrition, Faculty of Health
Science, Kyoto Koka Womens University, Japan

1

Possible involvement of central nesfatin-1 neurons in xenin-induced
feeding suppression in rats
Hirofumi Hashimoto, Yoshiteru Seo

Department of Regulatory Physiology, Dokkyo Medical University, Japan

2P-118Adrenomedullin enhances chorda tympani nerve responses tosugars in mice
Shusuke Iwata1), Mayuko Inoue1), Keiko Yasumatsu1), Ryusuke Yoshida2,3),
Yuzo Ninomiya1,4)

1
Div Sensory Physiol, R&D Cent for Taste and Odor Sensing, Kyushu Univ, Japan, 2Sect
Oral Neurosci, Grad Sch Dent Sci, Kyushu Univ, Japan, 3OBT Res Cent, Grad Sch Dent Sci,
Kyushu Univ, Japan, 4Monell Chemical Senses Center, USA

2P-119

Dietary fat modulation of oral fatty acid sensitivity and preference inyoung men and women
Yuho Yamauchi, Mamiko Inoshita, Kyoko Ueshima, Yuki Uchida,
Keiko Morimoto

Dept.Environm. Health, Facult. Human Life & Environm, Sci., Nara Women's Univ., Japan

2P-120

Nutritional status of Japanese children with developmental disorders
Shuhei Koeda1), Misaki Mikami1), Manabu Saito2,3), Tamaki Mikami3),
Kazuhiko Nakamura2,3), Junko Yamada1)

Hirosaki University Graduate School of Health Sciences, Japan, 2Department of
Neuropsychiatry, Hirosaki University Graduate School of Medicine, Japan, 3ResearchCenter for Child Mental Development, Hirosaki University Graduate School of Medicine,Japan
1★★2P-121(Y-12)The influence of central leptin signalling upon Obesity-induced hypertension
Stephanie Elise Simonds, Jack T Pryor, Tony Tiganis, Michael A Cowley
Monash University, Australia★★2P-122(Y-13)FKBP51 defect is resistant to diet induced obesity, inflammation andinsulin resistanceLuen-Kui Chen1), Chi-Chang Juan1,2,3)

Institute of Physiology, School of Medicine, National Yang-Ming University,
Department of Medical Research, Taipei Veterans General Hospital, 3Department of
Education and Research, Taipei City Hospital, Taiwan
12

2P-123

Leptin is a key regulator of glucose homeostasis in obesity
Jack Pryor, Stephanie Simonds, Michael Cowley

Department of Physiology, Monash University, Australia

Endocrine, Reproduction & Development (2)DAY 3

2P-117

2P-124

Visfatin promotes monocyte-endothelial cell adhesion via activationof p38-PI3K-Akt signaling
Chi-Chang Juan1,2,3), Yu-Ting Lin1), Deng-Yuan Jian1,4), Luen-Kui Chen1),
Tse-Ting Kuan1), Shao-Yun Wu1)

1
Institute of Physiology, National Yang-Ming University, Taiwan, 2Department of Medical
Research, Taipei Veterans General Hospital,Taiwan, 3Department of Education andResearch, Taipei City Hospital, Taiwan, 4Division of Nephrology, Wen-Lin Hemodialysis
Unit ,Taiwan

2P-125

Pin1 suppress thermogenesis through promoting the degradation of
PRDM16
Masa-ki Inoue, Yusuke Nakatsu, Takeshi Yamamotoya, Yasuka Matsunaga,
Yuki Inoue, Koji Ueda, Yu Mizuno, Tomoichiro Asano★ 2P-127(Y-14)

Department of Medical Science, Graduate School of Medicine, University of Hiroshima,Japan

Effect of Dapagliflozin on Glucose Metabolism and Renal andHepatic PEPCK Expression in Obese Rats
Myat Theingi Swe, Krit Jaikumkao, Laongdao Thonak,
Anchalee Pongchaidecha, Anusorn Lungkaphin
Epithelial Transport and Intracellular Signaling Regulation Unit, Department of
Physiology, Faculty of Medicine, Chiang Mai University, Thailand

2P-128

Tentonin 3/TMEM150C contributes to glucose-stimulated insulin
secretion in pancreatic β-cells
Jungwon Wee1,2), Gyusang Hong1), Sungmin Pak1), Uhtaek Oh1)

1
Brain Science Institue, Korea Institute of Science and Technology, Korea, 2Molecular
Medicine and Biopharmaceutical Sciences, Seoul National University, Korea

2P-129

Cytosolic phospholipase A2 in hypothalamus modulates systemic
glucose metabolism differently by meal
Ming-Liang Lee1), Hirokazu Matsunaga1), Takahiro Hayasaka2),
Yuko Okamatsu1), Kazuhiro Kimura1), Chitoku Toda1)
1
2

2P-130

Dept Biochemistry, Graduate School of Veterinary Medicine, Hokkaido University,
Dept Surgery, Graduate School of Medicine, Hokkaido University

Heterotypic endosomal fusion as an initial trigger for insulin-induced
GLUT4 translocation
Hiroyasu Hatakeyama1,2,3), Makoto Kanzaki3)

1
Department of Physiology, Kitasato University School of Medicine, Japan, 2Frontier
Research Institute for Interdisciplinary Sciences, Tohoku University, Japan, 3Graduate
School of Biomedical Engineering, Tohoku University, Japan

2P-131

Exogenous pyruvate maintains glycolysis-TCA cycle flux in Schwann
cell under high glucose conditions
Hideji Yako1), Naoko Niimi1), Ayako Kato2), Shizuka Takaku1), Koichi Kato2),
Kazunori Sango1)
1
2

2P-132Diabetic Neuropathy Project, Tokyo Metropolitan Institute of Medical science, Japan,
Laboratory of Medicine, Aichi Gakuin University, School of Pharmacy

Early life stress effect on pancreatic PDH level and Krebs cycle
enzymes activity in young adult rat
Mina Salimi1), Forouzan Sadeghimahalli2,4), Homeira Zardooz1,2),
Fariba Khodagholi3), Fatemeh Shaerzadeh5), Roxana Karbaschi2)

Neurophysiology Research Center, Shahid Beheshti University of Medical Sciences,Iran, 2Department of Physiology, School of Medicine, Shahid Beheshti University of1

Endocrine, Reproduction & Development (2)Medical Sciences, Iran, 3Neuroscience Research Center, Shahid Beheshti University of
Medical Sciences, Iran, 4Eduction Development Center, Mazandaran University of
Medical Science, Iran, 5Department of Physiology, Hormozgan University of Medical
Sciences, Iran2P-133Chronic maternal separation impaired glucose-dependent insulin
secretion from pancreatic islets
Homeira Zardooz1,2), Soheila Maghami2), Roxana Karbaschi2,3),
Mina Salimi1,2), Forouzan Sadeghimahalli4)

Neurophysiology Research Center, Shahid Beheshti University of Medical Sciences,
Iran , 2Department of Physiology, School of Medicine, Shahid Beheshti University of
Medical Sciences, Iran, 3Faculty of Nursing and Midwifery, Shahid Beheshti University of
Medical Sciences, Iran, 4Education Development Center, Mazandaran University of
Medical Sciences, Iran
1

Effect of maternal high-fat diet on HB9 expression and pancreatic
insulin secretion in male rats
Roxana Karbaschi1,2,3), Homeira Zardooz1,2), Mina Salimi1,2),
Forouzan Sadeghimahalli4), Rezvan Arian 2,5)

Department of physiology, School of Medicine, Shahid Beheshti University of Medical
Sciences, Iran, 2Neurophysiology Research Center, Shahid Beheshti University of
Medical Sciences, Iran. , 3Faculty of Nursing and Midwifery, Shahid Beheshti Universityof Medical Sciences, Iran. , 4Education Development Center, Educational Assistant,
Mazandaran University of Medical Science,Iran, 5Department of Dentistry, Shahid
Beheshti University of Medical Sciences, Iran1

2P-135

Postnatal stress induces morphological changes in islets ofLangerhans in stressed adult male rats
Forouzan Sadeghimahalli1,2), Homeira Zardooz2,3), Mina Salimi3),
Roxana Karbaschi2)

Educational Development Center, Mazandaran University of Medical Sciences, Iran,
Department of Physiology, Faculty of Medicine, Shahid Beheshti University of Medical
Sciences, Iran, 3Neurophysiology Research Center, Shahid Beheshti University of
Medical Sciences, Iran1
2

★ 2P-136(Y-15)

Correlation of median nerve parameters with TSH values in hypo­thyroid patients
Shital Gupta1), Rita Khadka1), Dilip Thakur1), Bishnu Hari Poudel1),
Kishun Deo Mehta2), Robin Maskey3)
Department of Basic & Clinical Physiology, B.P.Koirala Institute of Health Science, Nepal,
Department of Biochemistry, B.P.Koirala Institute of Health Science, Nepal, 3Department
of Internal Medicine, B.P.Koirala Institute of Health Sciences, Nepal
1
2

2P-137

Role of PCSK9 in lipid metabolic disorders and ovarian dysfunctionin polycystic ovary syndrome
Meijiao Wang1), Dan Zhao1), Liangzhi Xu2,3), Wenjing Guo1), Li Nie1),
Yun Long1), Min Liu1), Yichen Wang1), Xueqin Zhang1), Dongzhi Yuan1),
Limin Yue1)

Department of Physiology, West China School of Basic Medical Sciences and Forensic
Medicine, Sichuan University, China, 2Reproductive endocrinology and regulation jointlaboratory, West China Second University Hospital, Sichuan University, China,
3
Department of Obstetrics & Gynecology, West China Second University Hospital,
China
1

2P-138

Norepinephrine inhibits Th17 cells via beta2-adrenoreceptor signaling in collagen-induced arthritis
Yi-Hua Qiu, Yan Liu, Yu-Ping Peng

Department of Physiology, School of Medicine, Nantong University, China
Endocrine, Reproduction & Development (2)DAY 3

2P-134

2P-139

Roles of macrophages and PAI-1 in diabetic delayed bone repair in
female mice
Naoyuki Kawao1), Takeshi Shimoide1), Yukinori Tamura1), Kiyotaka Okada1),
Katsumi Okumoto2), Shinji Kurashimo2), Yoshitaka Horiuchi2),
Kohei Tatsumi1), Osamu Matsuo1), Hiroshi Kaji1),

Department of Physiology and Regenerative Medicine, Kindai University Faculty of
Medicine, Japan, 2Life Science Research Institute, Kindai University

1

2P-140Mechanical allodynia caused by peripheral nerve hyperexcitability inadult-onset hypothyroid mice
Machiko Suda1), Yusuke Takatsuru2), Noriyuki Koibuchi1)

Department of Integrative Physiology, Gunma University, Japan, 2Department ofMedicine, Johmoh Hospital, Japan1

2P-141

Ketogenic diet induces slow-type shift of skeletal muscle in male rat
Yuji Ogura1), Mitsutoshi Kurosaka1), Chiaki Kakehashi1), Ryo Kakigi2),
Tatsuo Akema1), Toshiya Funabashi1)

Department of Physiology, St. Marianna University School of Medicine, Japan,
Department of Physiology, Juntendo University Faculty of Medicine, Japan1
2

2P-142Administration of xylooligosaccharides from rice husk delayed theprogression of diabetic rat model
Narissara Lailerd1), Parichart Toejing1), Nuntawat Khat-Udomkiri2),
Sasithorn Sirilun2), Chaiyavat Chaiyasut2)

Department of Physiology, Faculty of Medicine, Chiang Mai University, Thailand,
Innovation Center for Holistic Health, Nutraceuticals and Cosmeceuticals, Faculty of
Pharmacy, Chiang Mai University, Thailand

12

2P-143

Improvement of organ bath technique as ex vivo systems in theinsulin secretion assay
Motoshi Ouchi1), Asuka Morita1), Keitaro Satoh2), Hidefumi Wakashin3),
Hiroe Kon4), Misao Terada4), Tomoe Fujita1)

Department of Pharmacology and Toxicology, Dokkyo Medical University School of
Medicine, Japan, 2Department of Pharmacology, Asahi University School of Dentistry,3
Department of Regulatory Physiology, Dokkyo Medical University School of Medicine,
4
Laboratory Animal Research Center, Dokkyo Medical University
1

2P-144

Responsiveness of vomeronasal cells to a male-attractant, imorin in
the newt, Cynops pyrrhogaster
Fumiyo Toyoda1), Tomoaki Nakada2), Kouhei Matsuda3), Takashi Nakakura4),
Itaru Hasunuma5), Kazutoshi Yamamoto6), Sakae Kikuyama6)

Department of Neurophysiology, Nara Medical University, Japan, 2Department ofComparative and Behavioral Medicine, Nippon Veterinary and Life Science University,
Japan, 3Laboratory of Regulatory Biology, Graduate School of Science and Engineering,
University of Toyama, Japan, 4Department of Anatomy and Cell Biology, Teikyo
University School of Medicine, Japan, 5Department of Biology, Faculty of Science, Toho
University, Japan, 6Department of Biology, Faculty of Education and Integrated
Sciences, Waseda University, Japan1

2P-145

Uterine environment regulates nurturing behavior in the offspringwith prolactin as a key factor
Taku James Sairenji1), Shinnosuke Masuda1), Oh Kwan Ee1),
Ryosuke Kaneko2), Saya Kodohira3), Yuri Shirakawa3), Chieko Yamazaki3),
Noriaki Shimokawa1,3), Noriyuki Koibuchi1)

Department of Integrative Physiology, Gunma University, Japan, 2Bioresource Center,
Gunma University, Japan, 3Department of Nutrition, Takasaki University of Health and1

Endocrine, Reproduction & Development (2)Welfare, Japan

2P-146

Effect of maternal high-fat diet and exercise during gestation onplacental signaling
Lin Song, Bo Sun, Jianqun Yan

Department of Physiology & Pathophysiology, Xi' an Jiaotong University, China

2P-147

Fetal heart rate variability: a biomarker for evolving fetal hypoxicischaemic brain injury
Yoshiki Maeda1,2), Christopher A Lear1), Michi Kasai1,3), Michael J Beacom1),
Victoria King1), Joanne Davidson1), Tomoaki Ikeda2), Alistair Jan Gunn1),
Laura Bennet1)

2P-148

Evaluation of spontaneous behaviors on an elevated plus mazeusing bisphenol A exposure model
Tetsuya Fujimoto1), Shuji Aou2)

Department of Physiology, Osaka Dental University, Japan, 2Department of HumanIntelligence Systems, Kyushu Institute of Technology, Japan1

2P-149Genistein and daidzein augments thyroid hormone-mediateddendritogenesis of cerebellar Purkinje cell
Winda Ariyani1), Wataru Miyazaki1), Yu Lu2), Toshiharu Iwasaki3),
Noriyuki Koibuchi1)

Department of Integrative Physiology, Gunma University, Japan, 2Department of
Physiology, College of Basic Medical Sciences, Jilin University, China., 3Department of
Liberal Arts and Human Development, Kanagawa University of Human Services, Japan1

2P-150

Positive effects of reduced nocturnal screen light on sleep in bedtime
phone users
Chuan Li, Augustine WL Li, Chun Lok Wu, Zenab Bibi

School of Medical and Health Sciences, Tung Wah College, Hong Kong

2P-151

Association of sex and sex hormones with the functional brain
network at rest
Tomohiro Donishi1), Masaki Terada2), Yoshiki Kaneoke1)

Department of System Neurophysiology, Graduate School of Wakayama Medical
University, Japan, 2Wakayama-Minami Radiology Clinic, Japan1

2P-152

The relationships between embryogenic outcome and membranepotential of mouse ova
Masao Miyake1), Susumu Yoshie1), Satoru Kaneko2), Akihiro Hazama1)

Department of Cellular and Integrative Physiology, Fukushima Medical University,
Japan, 2 Ichikawa General Hospital, Tokyo Dental College, Japan1

2P-153

Regulation of hyperactivation by interactions among oviductal
hormones in hamster sperm
Masakatsu Fujinoki

Department of Physiology, Dokkyo Medical University, Japan

2P-154

Proteomics analysis of whole testis in cordycepin treatment in
streptozotocin-induced diabetic miceWirasak Fungfuang1), Kongphop Paranyakul1), Krittika Srisuksai1),
Sittiruk Roytakul2)

1
Department of Zoology, Faculty of Science, Kasetsart University, Thailand, 2Proteomics
Research Laboratory, National Center for Genetic Engineering and Biotechnology,
Thailand
Endocrine, Reproduction & Development (2)

DAY 3

1
Department of physiology, The University of Auckland, New Zealand, 2Department of
Obstertrics and Gynecology, Mie University, Japan, 3Department of Obstetrics andGynecology, Yokohama Municipal University, Japan

★★2P-155(Y-16)

Overexpression of Anthrax toxin receptor 2 (ANTXR2) promotes early development of endometriosis
Shih-Chieh Lin1), Hsiu-Chi Lee2), Ching-Ting Hsu1), Yi-Han Huang1),
Wan-Ning Li2), Pei-Ling Hsu1), Meng-Hsing Wu3), Shaw-Jenq Tsai1)

Department of Physiology, College of Medicine, National Cheng Kung University,
Taiwan, 2Institute of Basic Medical Sciences, College of Medicine, National Cheng Kung
University, 3Department of Obstetrics & Gynecology, College of Medicine, National
Cheng Kung University and Hospital1

2P-156

Promoting follicle development by inducing ovarian angiogenesis
Kouji Komatsu, Satoru Masubuchi

Department of Physiology, Aichi Medical University, Japan

2P-157

Repression of COUP-TFII by proinflammatory cytokines contributes
to endometriotic lymphangiogenesis
Wan-Ning Li1), Kuei-Yang Hsiao5), Chu-An Wang3), Ning Chang2),
Meng-Hsing Wu4), Shaw-Jenq Tsai1,2)

The Institute of Basic Medical sciences, College of Medicine, National Cheng Kung
University, Taiwan, 2Departments of Physiology, College of Medicine, National Cheng
Kung University, Taiwan, 3Institute of Molecular Medicine, College of Medicine, National
Cheng Kung University, Taiwan, 4Obstetrics & Gynecology, College of Medicine,National Cheng Kung University, Taiwan, 5Graduate Institute of Biochemistry, National
Chung Hsing University, Taiwan
1

2P-158

Effects of exposure to mild hyperbaric oxygen on the outcome ofinfertility treatment
Tsuyoshi Shimizu1), Fumihiko Yoshikawa2), Yahiro Netsu3), Kaori Kamijou3),
Hiromi Hoshina2), Akihiko Ishihara4)

1
Shimizu Institute of Space Physiology Suwa Maternity Clinic, Japan, 2Suwa
Reproduction Center, Suwa Maternity Clinic, Japan, 3Suwa Maternity Clinic, Hospital for
Obstetrics,Gynecology and Pediatrics, Japan, 4Laboratory of Cell Biology and Life
Science, Graduate School of Human and Environmental Studies, Kyoto University,Japan

2P-159Insufficient in utero prolactin exposure causes impaired maternal
behavior in the offspring
Oh Kwan Ee1), Shinnosuke Masuda1), Taku James Sairenji1),
Noriaki Shimokawa2), Noriyuki Koibuchi1)

Department of Integrative Physiology, Gunma University Graduate School of Medicine,Japan, 2Department of Nutrition, Takasaki University of Health and Welfare, Japan1

2P-160Dominantly expressed Serpina3n suppresses the phenotypes ofosteoblasts of female mice
Masayoshi Ishida1), Naoyuki Kawao1), Kiyotaka Okada1), Kohei Tatsumi1),
Kazuko Sakai2), Kazuto Nishio2), Hiroshi Kaji1)

Department of Physiology & Regenerative Medicine, Kindai University Faculty of
Medicine, Japan, 2Department of Genome Biology, Kindai University Faculty of
Medicine
1

2P-161

The role of CTCF in the mammalian cochlea

Ji-Hyun Ma1), Jeong-Oh Shin1), Jong-Joo Lee2), Hyoung-Pyo Kim2,3),
Jinwoong Bok1,3,4)

1
Department of Anatomy, Yonsei University, Korea, 2Department of Environmental
Medical Biology, Republic of Korea, 3BK21 PLUS project for Medical Science,4
Department of Otorhinolaryngology, Yonsei University College of Medicine

Endocrine, Reproduction & Development (2)Neuroscience: Neural development and repair
2P-162

Electric axon guidance in embryonic retina: Regulation of integrin
activities by extracellular Ca2+
Masayuki Yamashita

Center for Medical Science, International University of Health and Welfare, Japan

2P-163

Improvement of motor function induced by skeletal muscle contractionin spinal cord injury rats
Norito Hayashi1,2), Naoyuki Himi1), Emi Nakamura-Maruyama1),
Naohiko Okabe1), Issei Sakamoto1,2), Toru Hasegawa2), Osamu Miyamoto1)

1
Department of Physiology2, Kawasaki Medical School, Japan, 2Department ofOrthopedics, Kawasaki Medical School, JapanTRPV4 is functionally expressed in cultured mouse Schwann cells
Xiaona Feng1,2,3), Yasunori Takayama1,2), Makoto Tominaga1,2,3)

1
Division of Cell Signaling, National Institute for Physiological Sciences, Japan , 2Thermal
Biology Group, Exploratory Research Center on Life and Living Systems (ExCELLS),
3
Department of Physiological Sciences, The Graduate University for Advanced Studies(SOKENDAI)

2P-165

Spontaneous network activity in the embryonic CNS analyzed with
voltage-sensitive dye recording
Katsushige Sato1), Yoko Momose-Sato2)

Department of Health and Nutrition Sciences, Faculty of Human Health, Komazawa
Women's University, Japan, 2Department of Nutrition and Dietetics, College of Nutrition,
Kanto-Gakuin University, Japan1

2P-166

Optical analysis of functional development of the mouse vestibular
nucleus
Yoko Momose-Sato1), Katsushige Sato2)

Department of Nutrition and Dietetics, College of Nutrition, Kanto-Gakuin University,
Japan, 2Department of Health and Nutrition Sciences, Faculty of Human Health,Komazawa Women's University, Japan1

2P-167

Sexual differentiation of the preoptic area by estrogen-induced cell
migration through Rac1 pathway
Tomohiro Hamada1), Yasuo Sakuma2)

Clinical Departments Laboratory, Nippon Medical School, Japan, 2Faculty of
Rehabilitation, School of Allied Health Sciences, University of Tokyo Health Sciences,
Japan

1

2P-168

Neuronal differentiation induced by vitamin K and generation ofderivatives to treat brain diseases
Yoshihisa Hirota1,2), Yuta Takagi2), Yutaro Yamashita1), Mayu Okazeri1),
Yoshitomo Suhara1,2)

Department of Bioscience and Engineering , College of Systems Engineering andSciences, Shibaura Institute of Technology, Japan, 2Systems Engineering and Science ,Graduate School of Engineering and Science, Shibaura Institute of Technology
12P-169Intranasal IGF-1 reduced neonatal LPS-induced behavioral deficits
and inflammation in juvenile rats
Lu-Tai Tien1), Yih-Jing Lee1), Chih-Hsueh Tseng1), Lir-Wan Fan2)

1
School of Medicine, Fu Jen Catholic University, Taiwan, 2Department of Pediatrics,
Division of Newborn Medicine, University of Mississippi Medical Center, USA

Neuroscience: Neural development and repair

DAY 3

2P-164

2P-170

Early exercise inhibits inflammation and promotes neuroprotection in
intracerebral hemorrhage rats
Keigo Tamakoshi, Keishi Hayao, Hideaki Takahashi, Hiroyuki Tamaki

Department of Physical Therapy, Niigata University of Health and Welfare, Japan

2P-171Glial cells missing 1 promote cell differentiation and angiogenesis in
the mammalian brain
Yoshitaka Hayashi, Satoshi Fuke, Takahiro Fuchigami, Naoko Morimura,
Natsu Koyama, Seiji Hitoshi
Department of Integrative Physiology, Shiga University of Medical Science, Japan

2P-172The effect of forced limb training of rats under photochemicallyinduced focal cerebral ischemia
Junko Yamada, Kazuki Akahira, Misaki Mikami, Yuuri Kato, Chihiro Sato

Department of Comprehensive Rehabilitation Science, Hirosaki University Graduate
School of Health Sciences, Japan

2P-173

Role of SAD-A kinase in radial neuronal migration during development of cerebral cortex
Keiko Nakanishi1,2), Hiroyuki Niida3,4), Hidenori Tabata5),
Yoshikazu Johmura3,6), Kenichiro Yamada7), Koh-Ichi Nagata5),Nobuaki Wakamatsu7), Masashi Kishi8), Yujiro Higashi2),
Makoto Nakanishi3,6),

Department of Pediatrics, Central Hospital, Aichi Human Service Center, Japan,
Department of Perinatology, Institute for Developmental Research, Aichi Human
Service Center, Japan, 3Department of Cell Biology, Graduate School of Medical
Sciences, Nagoya City University, Japan, 4Department of Molecular Biology, Hamamatsu
University School of Medicine, Japan, 5Department of Molecular Neurobiology, Institutefor Developmental Research, Aichi Human Service Center, Japan, 6Division of Cancer
Cell Biology, Department of Cancer Biology, Institute of Medical Sciences, The Universityof Tokyo, Japan, 7Department of Genetics, Institute for Developmental Research, Aichi
Human Service Center, Japan, 8Neuroscience Laboratory, Research Institute, Nozaki
Tokushukai Hospital, Japan1
2

2P-174

Voluntary and forced rehabilitation to promote motor palsy recovery
in intracerebral hemorrhage rats
Chihiro Sato1), Kunikazu Tanji2), Shuji Shimoyama2), Misaki Mikami1),
Kazuki Akahira1), Junko Yamada1)

Department of Health Science, University of Hirosaki, Japan , 2Department of Medicine,
University of Hirosaki, Japan1

2P-175

Alteration of gut microbiota and cerebellar structures in Glyphosateexposure rat
Kana Miyamoto1), Ken Futagami1), Kwon Soon Thomas Tiong1),
Yuu Hirose1), Jianzhong Hu2), Yoko Nomura3), Yasunari Kanda4),
Sachiko Yoshida1)

Department of Environmental and Life Science, Toyohashi University of Technology,
Japan, 2Icahn school of medicine at Mount Sinai, USA, 3Queens College, the City
University of New York, USA, 4National Institute of Health Sciences, Japan1

2P-176

Analysis of rat fetal movement before and after anesthetic drug using
non-anesthesia pregnant rat
Suzuka Hashiguchi1,2), Hodaka Natsuka1,2), Marin Tanimoto1,2),
Akira Tamaki1), Akiko Arata2)

Physical Ther. for Int. Disorders, Sch. of Rehabilitation, Hyogo Univ of Helth Sci., Japan,
Department of Physiology, Hyogo College of Medicine, Japan1
2

Neuroscience: Neural development and repair

2P-177

Altered gut flora and cerebellar development abnormalities in VPA rat
model of ASD
Kwong Soon Thomas Tiong1), Seita Sato1), Kana Miyamoto1), Yuu Hirose1),
Yasunari Kanda2), Sachiko Yoshida1)

Department of Environmental and Life Sciences, Toyohashi University of Technology,
Japan, 2Division of Pharmacology, National Institute of Health Sciences, Japan1

2P-178

Histological analysis of peripheral nerve injury in methylmercuryexposed rat
Yo Shinoda1), Shunsuke Ehara1), Satoshi Tatsumi1), Tatsuro Amemiya1),
Eiko Yoshida2), Tsutomu Takahashi1), Toshiyuki Kaji2), Yasuyuki Fujiwara1)
1

The role of Cdon in differentiation of mouse embryonic stem cells into
motor neurons
Seul-Yi Lee1,3), Hye-Been Kim2,3), Jong-Sun Kang2,3), Hana Cho1,3)

1Department of Physiology, Korea, 2Department of Molecular Cell Biology, 3Cell
Network Research Center, Sungkyunkwan University School of Medicine, Korea

2P-180PlexinA1 is crucial for the midline crossing of callosal axons during
corpus callosum development
Md Mosharaf Hossain1), Takuji Ito2), Takamasa Tsuzuki1),
Fumitaka Imaizumi1), Kana Kamiya1), Mitsuki Okada1), Ikuko Takahashi1),
Takayuki Negishi1), Kazunori Yukawa1)
1

2P-181

Department of Pharmacy, Meijo University, Japan, 2Aichi Medical University

The maintenance of adult neural stem cells by Klf5 gene

Anri Kuroda1), Takahiro Fuchigami1), Natsu Koyama1), Masatsugu Ema2),
Seiji Hitoshi1)

1
Department of Physiology, Shiga University of Medical Science, Japan, 2ResearchCenter for Animal Life Science, Shiga University of Medical Science, Japan

2P-182

Upregulation of heat shock factor and Factor XIII-A after optic nerve
injury in zebrafish
Kayo Sugitani1), Kazuhiro Ogai2), Yoshiki Koriyama 3), Satoru Kato2)

1
Div Health Sci, Grad Sch Med Sci, Kanazawa Univ, Japan , 2Wellness Promotion Science
Center, Institute of Medical, Pharmaceutical and Health Sci., Kanazawa Univ., Japan,
3
Grad. Sch. Pharm Sci, Suzuka University of Med Sci, Japan

2P-183

Oligodendrocyte progenitor cells during development and upon
sensory loss in mouse visual cortex
Hyeryun Shin, Hideki Derek Kawai

Department of Bioinformatics, Soka University, Japan

2P-184

Enhanced neuronal migration through activated glia promotes poststroke neuronal regeneration
Naoko Kaneko1), Vicente Herranz-Pérez2,3), Takeshi Otsuka4), Hiromi Sano5),
Nobuhiko Ohno6,7), Taichi Omata1), Huy Bang Nguyen7), Truc Quynh Thai7),
Jose Manuel García-Verdugo2), Kazunobu Sawamoto1,8),

Department of Developmental and Regenerative Biology, Nagoya City University
Graduate School of Medical Sciences, Japan, 2Laboratory of Comparative Neurobiology,
Instituto Cavanilles, Universidad de Valencia, CIBERNED, 3Predepartamental Unit ofMedicine, Faculty of Health Sciences, Universitat Jaume I, 4Division of Cerebral Circuitry,
National Institute for Physiological Sciences, 5Division of System Neurophysiology,
National Institute for Physiological Sciences, 6Department of Anatomy, Division ofHistology and Cell Biology, Jichi Medical University School of Medicine, 7Division of
1

Neuroscience: Neural development and repair

DAY 3

2P-179

Tokyo University of Pharmacy and Life Sciences, Japan, 2Tokyo University of ScienceNeurobiology and Bioinformatics, National Institute for Physiological Sciences, 8Divisionof Neural Development and Regeneration, National Institute for Physiological Sciences

2P-185

Postnatal development of core fields in the mouse auditory cortex
Feifan Chen, Wenjie Song, Makoto Takemoto, Masataka Nishimura,
Ryohei Tomioka

Department of Sensory and Cognitive Physiology, University of Kumamoto, Japan

2P-186Moduration of CRMP2 Accelerates Motor Function Recovery from
Brain Damage
Susumu Jitsuki1), Hiroki Abe1), Waki Nakajima1), Aoi Jitsuki-Takahashi1),
Hitoshi Masuyama2), Takashi Komori2), Nobuyuki Mochizuki2),
Tomohiro Okuda2), Yoshio Goshima3), Takuya Takahashi1),1Department of Physiology, Yokohama City University, Japan, 2Pharmacology Research
Department, Toyama Chemical Co., LTD., Japan, 3Department of Molecular
Pharmacology and Neurobiology, Yokohama City University, Japan

2P-187

Neurochemical differentiation of hypothalamic MCH neurons derived
from mouse embryonic stem cells
Yu Kodani1), Hidetaka Suga2), Yoko S Kaneko1), Miho Kawata1),
Akira Nakashima3), Hiroshi Nagasaki1)

Department of Physiology, Fujita Health University School of Medicine, Japan,
Department of Endocrinology & Diabetes, Nagoya University, Graduate School of
Medicine, Japan, 3Department of Physiological Chemistry, Fujita Health University
School of Medicine, Japan1
2

Neuroscience: Synapse & neural cellular communication (2)2P-188Accelerated climbing fiber synapse elimination in cerebellar Purkinjecells lacking protocadherin 10
Takaki Watanabe1,2), Shutaro Inoue1), Tsubasa Akamatsu1), Honoka Suzuki1),
Manabu Abe3), Kenji Sakimura3), Naofumi Uesaka1,2), Masanobu Kano1,2)1Dept. of Neurophysiol., Grad. Sch. of Med., Univ. of Tokyo, Japan, 2WPI-IRCN, UTIAS,
Univ. of Tokyo, Japan, 3Dept. of Cell. Neurobiol., Brain Res. Inst., Niigata Univ., Japan

2P-189Vesicular GABA Uptake can be Rate-Limiting for Recovery of IPSCs
from Synaptic Depression
Manami Yamashita1,2), Shin-ya Kawaguchi3), Tetsuya Hori4),
Tomoyuki Takahashi5)

1
Department of Physiology, Osaka Medical College, Japan, 2Laboratory of MolecularSynaptic Function, Graduate School of Brain Science, Doshisha University, Japan,
3
Society-Academia Collaboration for Innovation, Kyoto University, Japan, 4Departmentof Neurophysiology, Graduate School of Life and Medical Sciences, Doshisha University,
Japan, 5Cellular and Molecular Synaptic Function Unit, Okinawa Institute of Science andTechnology (OIST) Graduate University, Japan

2P-190M1 receptor-mediated presynaptic inhibition of IPSCs in basal
forebrain cholinergic neurons
Toshihiko Momiyama, Takuma Nishijo

Department of Pharmacology, The Jikei University School of Medicine, Japan

2P-191

Construction Rules of the Axospinous Synapses Revealed by FIBSEM Imaging
Yugo Fukazawa1,2,3), Taito Sakurai1,4), Ruwaida Elhanbaly1,5),
Tatsuya Ishikawa1,6)

1
Division of Brain Structure and Function, University of Fukui, Japan, 2Life Science
Innovation Center, University of Fukui, Japan, 3Research Center for Child Mental

Neuroscience: Neural development and repair/Neuroscience: Synapse & neural cellular communication (2)Development, University of Fukui, Japan, 4Rakuhoku High School, Japan, 5Departmentof Anatomy, Histology and Embryology, Faculty of Veterinary Medicine, Assiut
University, Egypt, 6Department of Functional Anatomy, Kanazawa University Graduate
School of Medical Sciences, Japan

2P-192Analysis of the central circadian clock in AVP neuron-specific VGAT
deficient mice
Takashi Maejima1), Emi Hasegawa2), Yusuke Tsuno1), Michihiro Mieda1)

Department of Integrative Neurophysiology, Kanazawa University Graduate School of
Medical Sciences, Japan, 2International Institute for Integrative Sleep Medicine,
University of Tsukuba, Japan1

2P-193

Regulation of reciprocal current in the mouse accessory olfactory
bulb by vasopressin V1a receptors
Department of Physiology, Kochi Medical School, Kochi University, Japan

2P-194

The activity of metabotropic glutamate receptor affects drebrin
localization in dendritic spines
Nobuhiko Kojima1), Mai Sawabe1), Kaiin Shu1), Kenji Hanamura2),
Tomoaki Shirao2)

Faculty of Life Sciences, Toyo University, Japan, 2Gunma University, Graduate School of
Medicine, Japan1

2P-195

Dopamine induced long-lasting calcium increase in orexin neurons
via D1-like receptor
Yasutaka Mukai1,2,3,4), Kenji F Tanaka5), Takeharu Nagai6),
Akihiro Yamanaka1,2,3)

1
Department of Neuroscience II, RIEM, Nagoya University, Japan, 2Department of
Neuralregulation, Graduate School of Medicine, Nagoya University, Japan, 3CREST,
Japan Science and Technology Agency, Japan, 4Research Fellowship for Young
Scientists (DC1), Japan Society for the Promotion of Science, Japan, 5Department of
Neuropsychiatry, Graduate School of Medicine, Keio University, Japan, 6Department of
Biomolecular Science and Engineering, ISIR, Osaka University, Japan

2P-196

Drebrin depletion affects stability of microtubules in dendrites
Noriko Koganezawa, Hiroyuki Yamazaki, Tomoaki Shirao

Department of Neurobiology and Behavior, Gunma University Graduate School of
Medicine, Japan

2P-197

Induction of electrophysiologically-active brain organoids showing
human midbrain-specific structure
Takeshi Ken Matsui1,3), Nobuyuki Eura1), Hitoki Nanaura1), Tomo Shiota1),
Yasuhiko Saitoh2), Kazuma Sugie1), Eiichiro Mori3)

1
Department of Neurology, Nara Medical University, Japan, 2Department of Physiology
I, Nara Medical University, Japan, 3Department of Future Basic Medicine, Nara Medical
University, Japan

2P-198C1ql1-Bai3 Signaling Dynamically Modulates Climbing Fiber Syna­pses in Adult Cerebellum
Takahiro Aimi, Wataru Kakegawa, Michisuke Yuzaki

Department of Physiology, Keio University School of Medicine, Japan

2P-199Layer 5 sublayer-dependent excitatory-inhibitory connections in the
rat frontal cortex
Mieko Morishima1,2), Yasuo Kawaguchi1,2)
1
2

Division of Cerebral Circuitry, National Institute for Physiological Sciences, Japan,
SOKENDAINeuroscience: Synapse & neural cellular communication (2)DAY 3

Mutsuo Taniguchi, Yoshihiro Murata, Masahiro Yamaguchi, Hideto Kaba

2P-200

Phasic inhibition in the interval of carbachol-induced β oscillation in
rat hippocampal
Toyohiro Sawada, Kiyohisa Natsume

Dept. of Brain Sci. and Eng., Grad. Sch. of Life Sci. and Sys. Eng., Kyusyu Inst. of Tech.,Japan

Neuroscience: Neuron-glia interactions / functions of glia
2P-201

Exendin-4 promotes myelination in a co-culture of DRG neurons andimmortalized Schwann cells IFRS1
Kazunori Sango, Shizuka Takaku, Masami Tsukamoto, Naoko Niimi,
Hideji Yako

Diabetic Neuropathy Project, Tokyo Metropolitan Institute of Medical Science, Japan

2P-202Loss-of-function of glial ABCA1 increases the risk for pathogenesis ofglaucoma
Youichi Shinozaki1), Kazuhiko Namekata2), Kenji Kashiwagi3),
Nobuhiko Ohno4,5), Akiko Takeda1), Takayuki Harada2), Schuichi Koizumi1)

Department of Neuropharmacology, University of Yamanashi, Japan, 2Vis. Res. Project,Tokyo Metr. Inst. Med. Sci., Japan, 3Dept. Ophthalmol, Interdiscip. Grad. Sch. Med. Univ.
Yamanashi, JAPAN, 4Dev. Neurobiol. Bioinfo., Natl. Inst. Physiol. Sci., Japan, 5Div. Anatomy,
Jichi Med. Univ. Japan1

2P-203

Müller glial swelling activates TRPV4 and triggers photoreceptor cell
death at body temperature
Koji Shibasaki1), Hidetaka Matsumoto2), François Seghers3), David Krizaj4),
Hideo Akiyama2), Yasuki Ishizaki1), Philippe Gailly3)

1
Dep. Mol. Cellular Neurobiology, Gunma Univ. Grad. Sch. Medicine, Japan, 2Dep.
Opthalmology, Gunma Univ., Japan, 3Instit. Neurosci., Univ. Catholique de Louvain,
Belgium, 4Moran Eye Instit., Univer. Utah School of Medicine, United States

2P-204Stress-Induced Microglial Activation Occurs through a betaAdrenergic Receptor
Shuei Sugama, Hisayuki Ohata, Yasuhiro Takenaka, Yoshihiko Kakinuma
Department of Physiology, Nippon Medical School, Japan

2P-205

Electrophysiological approach with ex vivo trigeminal ganglia toclarify neuron-glia interactions
Asako Kubo1), Shiori Sugawara1,2), Koichi Iwata1)

1
Department of Physiology, School of Dentistry Nihon University, Japan, 2Departmentof Psychosomatic Dentistry, Graduate School of Medical and Dental Sciences, Tokyo
Medical and Dental University, Japan

2P-206

The role of primary somatosensory cortex in causing mirror image
pain
Tatsuya Ishikawa1,2), Kei Eto2,3), Noriyuki Ozaki1), Hitoshi Ishibashi4),
Junichi Nabekura2,3)

1
Department of Functional Anatomy, Kanazawa University, Japan, 2Department ofDevelopment Physiology, National Institute for Physiological Sciences, Japan,
3
Department of Physiological Sciences, The Graduate School for Advanced Study,
Japan, 4Department of Physiology, Kitasato University School of Allied Health Sciences,Japan

2P-207Visualization of spatiotemporal interaction of neurons and astrocytes
Eiji Shigetomi1), Yukiho J Hirayama1), Kazuhiro Ikenaka2), Kenji F Tanaka3),

Neuroscience: Synapse & neural cellular communication (2)/Neuroscience: Neuron-glia interactions / functions of glia

Haruhiko Bito4), Schuichi Koizumi1)
University of Yamanashi, Interdisciplinary Graduate School of Medicine, University of
Yamanashi, Japan, 2Division of Neurobiology and Bioinformatics, NIPS, Japan,
Department of Neuropsychiatry, Keio University School of Medicine, Japan,
4
Department of Neurochemistry, Graduate School of Medicine, University of Tokyo,
Japan
1

3

2P-208

Activation of TRPV4 induced significant ATP release in Müller glia
Shouta Sugio1,2), Hidetaka Matsumoto3), Mai Oda2), Yasuki Ishizaki2),
Koji Shibasaki2)

Division of System Neuroscience, Kobe University School of Medicine, Japan,
Department of Molecular and Cellular Neurobiology, Gunma University School of
Medicine, Japan, 3Department of Ophthalmology, Gunma University School of
Medicine, Japan

1
2

Excitatory synaptic transmission is reduced by astrocytes previously
exposed to amyloid β 1-40
Kohei Oyabu1), Hiroyuki Kawano1), Hideaki Yamamoto2), Kei Eto3,4),
Yuna Adaniya1), Kaori Kubota1,5), Takuya Watanabe1,5),
Ayumi Hirano-Iwata6,7), Junichi Nabekura4,8,9), Shutaro Katsurabayashi1),
Katsunori Iwasaki1,5)

1
Department of Neuropharmacology, University of Fukuoka, Japan, 2Frontier ResearchInstitute for Interdisciplinary Sciences, Tohoku University, Japan, 3Division ofHomeostatic Development, Department of Fundamental Neuroscience, National
Institute for Physiological Sciences, Japan, 4Department of Physiological Sciences, The
Graduate University for Advanced Studies (SOKENDAI), Japan, 5A.I.G. Collaborative
Research Institute for Aging and Brain Sciences, Fukuoka University, Japan, 6Advanced
Institute for Materials Research, Tohoku University, Japan, 7Research Institute ofElectrical Communication, Tohoku University, Japan, 8Division of Homeostatic
Development, Department of Developmental Physiology, National Institute forPhysiological Sciences, Japan, 9CREST, Japan Science and Technology Agency (JST),Japan

2P-210

Acute stress induced the alterations of astrocytes and glutamate
receptors in the hippocampus of rat
Ratchaniporn Kongsui1), Rohan Frederick Walker2,3), Napatr Sriraksa1),
Tichanon Promsrisuk1)

Division of Physiology, School of Medical Sciences, University of Phayao, Thailand,
School of Biomedical Sciences and Pharmacy and the Priority Research Centre for
Stroke and Brain Injury, University of Newcastle, Australia, 3Hunter Medical ResearchInstitute, Australia

12

2P-211Visualizing the Interaction of Immune Cells and Peripheral Sensory
Fibers in Mice Neuropathic Model
Han-Yuan Yeh1), Chen-Chi Wang2), Han-Hsiung Chi1), Jye-Chang Lee1),
Masakazu Agetsuma3), Junichi Nabekura3)

Department of Life Science, National Taiwan University, Taiwan, 2Center of Experimental
Animals, National Institute of Physiological Science, Japan, 3Division of Homeostatic
Development, National Institute of Physiological Science, Japan1

2P-212

Tonic release of D-serine through Best1 channel is critical for longterm depression
Wuhyun Koh1,2,4), Jaekwang Lee3), Mijeong Park3), Ye Eun Chun2,4),
Hey Yun Kim6), Junsung Woo2), Soo-Jin Oh6), Changjoon Justin Lee1,2,4,5)Center for Glia-Neuron Interaction, Korea Institute of Science and Technology (KIST),
Korea, 2Center for Functional Connectomics, Korea Institute of Science and Technology,
Republic of Korea, 3Center for Neural Science, Korea Institute of Science and Technology,
Republic of Korea, 4Bio-med Department, University of Science and Technology (UST),
1

Neuroscience: Neuron-glia interactions / functions of glia

DAY 3

2P-209

★ 2P-213(Y-17)

Republic of Korea, 5KU-KIST School of Converging Science and Technology, Korea
University, Republic of Korea, 6Convergence Research Center for Dementia DTC, Korea
Institute of Science and Technology, Republic of Korea

TRPA1 channel is critical for gliotransmitter release from astrocyte
by eliciting calcium entry
Jung Moo Lee1,2), Soo-Jin Oh2,3), Wuhyun Koh2,4), Changjoon Justin Lee1,2)
KU-KIST Graduate School of Converging Science and Technology, Korea
University, Korea, 2Center for Glia-Neuron Interaction, Korea Institute of Science andTechnology (KIST), Republic of Korea, 3Convergence Research Center for Diagnosis,
Treatment and Care System of Dementia, Korea Institute of Science and Technology,
Republic of Korea, 4Division of Bio-Medical Science & Technology, KIST School, Korea
University of Science and Technology, Republic of Korea

1

2P-215

Astrocytes mediate persistent respiratory augmentation in therecovery phase after hypoxic exposure
Isato Fukushi1), Yosuke Kono1,2), Kotaro Takeda1,3), Shuntaro Okazaki4),
Shigefumi Yokota5), Itaru Yazawa6), Hiroshi Onimaru7), Yasumasa Okada1)

1
Clinical Research Center, Murayama Medical Center, Japan, 2Department of Pediatrics,
Faculty of Medicine, University of Yamanashi, 3School of Health Sciences, Fujita Health
University, 4Faculty of Human Sciences, Waseda University, 5Department of Anatomy
and Neuroscience, Shimane University School of Medicine, 6Global Research Center for
Innovative Life Science, Hoshi University, 7Department of Physiology, Showa University
School of Medicine

2P-216

AQP4 involvement in normalization of extracellular potassium after
acute ischemic stroke
Hiromu Monai1,2), Xiaowen Wang2), Kazuko Yahagi2), Nanhong Lou3),
Humberto Mestre3), Qiwu Xu3), Youichiro Abe4), Masato Yasui4),
Youichi Iwai2), Hajime Hirase2)

Ochanomizu University, Japan, 2RIKEN Center for Brain Science, 3University of Rochester
Medical Center, 4Keio University

1

2P-217

Efficacy of Cinnamomi Cortex & Coumarin on cold allodynia byoxaliplatin : modulating spinal gila
Ji Hwan Lee1,2), Woojin Kim1), Sun Kwang Kim1,2)

1
Department of Physiology, Korean Medicine, Kyung Hee University, Korea, 2Departmentof Science in Korean Medicine, Graduate School, Kyung Hee University, Korea

2P-218

Pioglitazone reversed the developmental programming of fructose in
the astrocytic glucose metabolism
Kay LH Wu, Chih-Wei Wu, Chung-Ying Hung

Institute for Translational Research in Biomedicine, Kaohsiung Chang Gung Memorial
Hospital, Taiwan

2P-219Microglial activation caused by lipopolysaccharide and trimethyltin
administration in the rat brain
Toshiyuki Saito1,2), Wakako Nakajima1), Nobuhiro Ishida1), Takayo Imori2)

Department of Life Sciences, Kyoto Sangyo University, Japan, 2Graduate School of Life
Sciences, Kyoto Sangyo University, Japan1

2P-220Brain area-dependent astrocyte heterogeneity detected in mice by
dopamine receptor expressions
Katsuhiro Nagatomo1), Kazuto Kobayashi2), Yoshio Yamamoto3),
Katsuya Yamada1)

1Dept. Physiol., Hirosaki Univ. Grad. Sch. Med., Japan, 2Dept. Mol. Genet., Inst. Biomed.
Sci., Fukushima Med. Univ. Sch. Med., Japan, 3Lab. Vet. Anat. Cell Biol., F. Agri., Iwate Univ.,Japan

Neuroscience: Neuron-glia interactions / functions of glia

2P-221Social defeat stress reduces newly born oligodendrocytes andinduces anxiety-like behavior in miceTakeshi Shimizu, Sawa Kondo, Akimasa Ishida, Naoki Tajiri, Hideki Hida

Department of Neurophysiology and Brain Science, Graduate School of Medical
Sciences, Nagoya City University, Japan

2P-222

Rediscovery of GIT1 hetero mice as more practical model for
hyperactivity
Yoo Sung Kim1), Junsung Woo2), C. Justin Lee2), Bo-Eun Yoon1)

1
Department of Molecular Biology, University of Dankook, Korea, 2Center for
Neuroscience and Functional Connectomics, Korea Institute of Science and Technology,
Korea

2P-223Functional connectivity changes after rTMS used to detect plasticity
decline associated with obesity
Shuyan Han1), Takahiro Osada1), Akitoshi Ogawa1), Masaki Tanaka1),
Masaaki Hori2), Shigeki Aoki2), Takahiro Shimizu3), Hiroyuki Enomoto4),
Ritsuko Hanajima3), Yoshikazu Ugawa4), Seiki Konishi1)

Department of Neurophysiology, Juntendo University School of Medicine, Japan,
Department of Radiology, Juntendo University School of Medicine, Japan, 3Departmentof Neurology, Tottori University School of Medicine, Japan, 4Department of NeuroRegeneration, Fukushima Medical University, Japan1
2

2P-224Visualization of the activation pattern causality during pain chro­
nification using DREADD-MEMRI
Daigo Arimura1,2,3), Kei Shinohara3), Yukari Takahashi1,2),
Tomokazu Tsurugizawa1,2,4), Ryo Ikeda3), Keishi Marumo3), Fusao Kato1,2)

1Department of Neuroscience, The Jikei University School of Medicine, Japan, 2Center
for Neuroscience of Pain, The Jikei University School of Medicine, Japan, 3Departmentof Orthopaedics, The Jikei University School of Medicine, Japan, 4Neurospin, France

2P-225

Correlation analysis of sister mitral and tufted cells
Yusuke Tsuno1,2), Matt Wachowiak1)

1
Department of Neurobiology and Anatomy, University of Utah, USA, 2Department ofIntegrative Neurophysiology, Graduate School of Medical Science, Kanazawa University,Japan

2P-226Novel fluoropolymer nanosheets extending in vivo two-photon imaging of living mouse brain
Taiga Takahashi1,2), Kenji Yarinome3), Hong Zhang4), Ryosuke Kawakami5),
Yosuke Okamura3,4), Tomomi Nemoto1,2)

1Research Institute for Electronic Science, Hokkaido University, Japan, 2Graduate Schoolof Information Science and Technology, Hokkaido University, Japan, 3Graduate Schoolof Engineering, Tokai University, Japan, 4Micro/Nano Technology Center, Tokai
University, Japan, 5Department of Molecular Medicine for Pathogenesis, Graduate
School of Medicine, Ehime University, Japan

2P-227

Wide-field imaging of neural activity with high spatial resolution
Masanori Matsuzaki, Shin-Ichiro Terada, Eriko Yoshida
Department of Physiology, The University of Tokyo, Japan

2P-2283-D visualization of avian brainstem auditory circuits using Brainbow
labeling and tissue clearing
Hiroshi Sekikawa1,2), Ryo Egawa2), Hiroshi Kuba2)
1

Dept. of Med., Japan, 2Cell. Physiol., Grad. Sch. of Med., Nagoya Univ.

Neuroscience: Neuron-glia interactions / functions of glia/Neuroscience: Imaging of brain

DAY 3

Neuroscience: Imaging of brain

2P-229

Anesthesia alters orientation and direction selective properties inmouse superior colliculus
Masatoshi Kasai, Tadashi Isa

Department of Neuroscience, Graduate School of Medicine, Kyoto University, Japan

2P-230Analysis of a novel higher visual area, ECT, in the mouse ventral
streamNana Nishio1,2), Hiroaki Tsukano2), Ryuichi Hishida2), Manabu Abe3),
Junichi Nakai4), Meiko Kawamura3), Atsushi Aiba5), Kenji Sakimura3),
Katsuei Shibuki2), Kenichi Ohki1),

1
Dept. Physiol, Univ of Tokyo, Japan, 2Dept Neurophysiol, BRI, Niigata Univ., Japan, 3Dept
Cell Neurobiol, BRI, Niigata Univ., Japan, 4BBSSI, Saitama Univ., Japan, 5Animal Resources,
CDBIM, Univ. of Tokyo., Japan

2P-231

An fMRI Study of Brain Network Involved in Elderly Teeth Tapping
Yosinori Sahara1), Hideyuki Fukami1,2)
1
2

2P-232

Department of Physiology, Iwate Medical University School of Dentistry, Japan,
Department of Oral Health Science, Baika Women's University, Japan

Hippocampus abnormalities evaluated by density imaging in COPD
patients
Natsuko Iizuka1,2), Yuri Masaoka 1), Masaki Yoshida 3), Ryo Manabe 4),
Koji Kamagata 5), Yuki Takenaka 5), Kentaro Okuda 6), Akira Yoshikawa1),
Satomi Kubota 1,2), Masahiro Ida 7), Masahiko Izumizaki 1)

1
Dept Physiol, Showa Univ, Japan, 2Dept Neulol, Showa Univ, Japan, 3Dept Ophthalmol,
Jikei Univ, Japan, 4Dept Respiratory Medicine and Allergology, Showa Univ, Japan,
5
Dept Radiol, Juntendo University Graduate School of Medicine, Japan, 6Dept Medicine,
Ebara Hospital, Japan, 7Dept Radiol, Ebara Hospital, Japan

2P-233

Relationship between Resting-State Functional Connectivity andcognitive function
Akira Yoshikawa1), Yuri Masaoka1), Masaki Yoshida2), Nobuyoshi Koiwa3),
Satomi Kubota1,4), Ryo Manabe1,5), Natsuko Iizuka1,4), Masahiro Ida6),
Masahiko Izumizaki1)

1
Department of Physiology, Showa University School of Medicine, Japan, 2Departmentof Ophthalmology, Jikei University School of Medicine, Japan, 3Human Arts andSciences Research Center, University of Human Arts and Sciences, Japan, 4Departmentof Neurology, Showa University School of Medicine, Japan, 5Department of Medicine,
Division of Respiratory Medicine and Allergology, Showa University School of Medicine,Japan, 6Department of Radiology, Comprehensive Stroke Center, Ebara Hospital, Japan

2P-234

Decoder construction for MEG signals in a subitizing task
Kouji Takano1), Kenji Kansaku1,2,3)

Department of Rehabilitation for Brain Functions, Research Institute of National
Rehabilitation Center For Persons with Disabilities, Japan, 2Department of Physiology
and Biological Information, Dokkyo Medical University School of Medicine, Japan,
3
Brain Science Inspired Life Support Research Center, The University of ElectroCommunications, Japan1

2P-235

Application of a Spatiotemporal Neural Network to Segment Low
Contrast Calcium Fluorescence Images
Pelonomi Moiloa, Noriyasu Homma, Makoto Osanai
Tohoku University, Japan

2P-236

Circuitry changes in Parkinson’s disease assessed by qAIM-MRI

Makoto Osanai1,2), Satomi Kikuta1,3), Pelonomi Moiloa2), Hiroki Tanihira1),
Neuroscience: Imaging of brain

Noriyasu Homma1,2)
Tohoku University Graduate School of Medicine, Japan, 2Graduate School of Biomedical
Engineering, Tohoku University, 3Primate Research Institute, Kyoto University

1

2P-237

Positron Emission Tomography Tracer for AMPA receptors Chara­cterizes Psychiatric Disorders in Human
Mai Hatano★ 2P-238(Y-18)

Department of Physiology, University of Yokohama City University, Japan

Molecular profiling of the subthalamic nucleus
Jiwon Kim1,2), Hyungju Jeon1), Hojin Lee1,2), Linqing Feng1), Jinhyun Kim1,2)
Center for Functional Connectomics, Korea Institute of Science and Technology (KIST),
Republic of Korea, 2Division of Bio-Medical Science & Technology, KIST-School,
University of Science and Technology (UST), Republic of Korea
1

Dynamics of local networks in the motor cortex during sleep andwakefulness
Takeshi Kanda1), Takehiro Miyazaki1), Daiki Nakatsuka1), Hideitsu Hino2),
Masashi Yanagisawa1)
1

2P-240

University of Tsukuba, Japan, 2The Institute of Statistical Mathematics

Relation between Montreal Cognitive Assessment and amygdalahippocampus volumes in the elderly
Satomi Kubota1,2), Yuri Masaoka1), Masaki Yoshida3), Ryuta Kinno2),
Akira Yoshikawa1), Ryo Manabe4), Natsuko Iizuka1,2), Masahiro Ida5),
Kenjirou Ono2), Masahiko Izumizaki1)

1
Department of Physiology, Showa University, Japan, 2Department of Neurology,
Showa University, Japan, 3Department of Opthalmology, Jikei University, Japan,
4
Department of Respiratory Medicine and Allergology, Showa University, Japan,
5
Department of Radiology, Ebara Hospital, Japan

2P-241

Sensory integration and behavioral choice regulated by the meta­
botropic glutamate receptor
Yuji Suehiro, Shohei Mitani

Department of Physiology, Tokyo Women's Medical University School of Medicine,Japan

2P-242

Two-photon imaging of neuronal activity in motor cortex of nonhuman primate during reaching tasks
Teppei Ebina, Yoshito Masamizu, Keitaro Obara, Masanori Matsuzaki

Department of Physiology, Graduate School of Medicine, The University of Tokyo, Japan

2P-243

Calcium imaging data from premotor area predict features ofupcoming movement
Wing-Ho Yung, Chunyue Li, Ya Ke

School of Biomedical Sciences, The Chinese University of Hong Kong, Hong Kong

2P-244

In vivo Ca2+ imaging of mouse brain by two-photon excitation spinning-disk confocal microscopy
Mitsutoshi Ataka1,2), Takafumi Kamada1,2), Kohei Otomo1,2),
Tomomi Nemoto1,2)

Graduate School of Information Science and Technology, Hokkaido University, Japan,
Laboratory of Molecular and Cellular Biophysics, Research Institute for Electronic
Science, Hokkaido University, Japan1
2

2P-245

Uptake and Release of Mn Ions from Neuron as a Basis of Mn MRI
Akio Inoue1), Yuriko Inoue2), Hiromitsu Ezure2), Naruto Ohtsuka2),
Neuroscience: Imaging of brain

DAY 3

2P-239

Yoshinobu Manome3), Koichi Shiraishi4), Akitoshi Inoue5)
Human Brain Research Center, Graduate School of Medicine, Kyoto University,
Department of Anatomy, Showa University, School of Medicine, 3Division of Molecular
and Cellular Bilogy, Research Center for Medicine, Jikei University, School of Medicine,
4
Division of Medical Engineering, Jikei University, School of Medicine, 5Department of
Molecular and Functional Biology, Kansai Medical University
1
2

2P-246

Two-photon laser ablation cut sole neural processes without severe
damage on surrounding astrocytes
Kazushi Yamaguchi1), Ryosuke Kawakami1,2), Tomomi Namoto1,2)

Graduate School of Information Science and Technology, Hokkaido University, Japan,
Research Institute for Electronic Science, Hokkaido University, Japan1
2

2P-247

Topical pH change in the brain by visual stimulation revealed by CCD
pH image sensor
Junko Ishida1), Hiroshi Horiuchi1), Masakazu Agetsuma1), Kazuaki Sawada2),
Junichi Nabekura1)

Division of Homeostatic Development, National Institute for Physiological Sciences,
Japan, 2Department of Electronic and Information Engineering, Toyohashi University ofTechnology, Japan1

2P-248Differential characteristics of D1 and D2-type medium spiny neuron
via cortico-striatal stimulation
Ryo Inagaki1,2), Masato Sasagawa3), Noriyasu Homma3), Makoto Osanai3)

1
Tohoku University Graduate School of Medicine, Japan, 2Brain/MINDS, 3Tohoku
University Graduate School of Medicine, Graduate School of Biomedical Engineering,Tohoku University

Neuroscience: Learning, memory & neuronal plasticity (2)2P-249Error signals in the red nucleus drive adaptation in reaching
Masato Inoue1), Shigeru Kitazawa2,3,4)

Global Center for Medical Engineering and Informatics, Osaka University, Japan,
Graduate School of Frontier Biosciences, Osaka University, 3Graduate School of
Medicine, Osaka University, 4Center for Information and Neural Networks (CiNet),
National Institute of Information and Communications Technology, and Osaka
University
1
2

2P-250Modulatory effects of dopamine on synaptic plasticity in hippo­campusof kindled mice
Nahid Roohi, Yaghoub Fathollahi, Mahboubeh Ahmadi,
Javad Mirnajafi-Zadeh

Department of Physiology, Tarbiat Modares University of Medical Sciences, Iran

2P-251

LTD is regulated by drebrin isoforms conversion likely due to thedifference in the isoform dynamics
Tomoaki Shirao1), Kenji Hanamura1), Nobuhiko Kojima2), Hiroki Yasuda3),
Yuko Sekino4)

1
Dept. of Neurobiology and Behavior, Gunma Univ. Grad. Sch. of Med., Japan, 2Dept. ofLife Sci., Faculty of Life Sci, Toyo University, Japan, 3Dept. of Physiol., Saga Univ. Sch. ofMed., Japan, 4Lab. of Human-Cell based Drug Discovery, Grad. Sch. of Pharm. Sci., Univ.
of Tokyo, Japan

2P-253A strategy of NMDA receptor-dependent oscillation in the visualcortex of rats
Hiroshi Yoshimura

Department of Molecular Oral Physiology, Institute of Biomedical Sciences, Tokushima
University Graduate School, Japan
Neuroscience: Imaging of brain/Neuroscience: Learning, memory & neuronal plasticity (2)2P-254

Retrieval-Induced Forgetting in Young Mice
Asahi Haijima, Noriyuki Koibuchi

Department of Integrative Physiology, Gunma University Graduate School of Medicine,Japan

2P-255The mitochondrial system of hippocampal adult-born neurons in theTg2576 mouse model
Trinovita Andraini1,2), Kevin Richetin2), Petnoi Petsophonsakul2),
Laurent Roybon3), Marie-Christine Miquel2), Claire Rampon2)

2P-256

Effects of PDIA3 on Neurogenesis in the Dentate Gyrus of Normal
and Ischemic Gerbils
In Koo Hwang1), Woosuk Kim1), Dae Young Yoo2), Su Bin Cho3),
Jong Whi Kim1), Yeo Sung Yoon1), Dae Won Kim4)

Department of Anatomy, College of Veterinary Medicine, Seoul National University,
South Korea, 2Department of Anatomy, College of Medicine, Soonchunhyang
University, South Korea, 3Department of Biomedical Sciences, and Research Institute for
Bioscience and Biotechnology, Hallym University, South Korea, 4Department ofBiochemistry and Molecular Biology, Research Institute of Oral Sciences, College ofDentistry, Gangneung-Wonju National University, South Korea
12P-257

Different mechanism of actions of testosterone and estradiol on
cognitive impairment in male rats
Taratorn Fainanta, Sukanya Jaroenporn, Thaweechai Saetae,
Patteera Wititsuwankul, Suchinda Malaivijitnond
Department of Biology, Chulalongkorn University, Thailand

2P-258Modulation of dentate granule cell activity during fear memory
extinction in freely moving miceAlvaro Carrier Ruiz1,2), Yuki Sugaya1,2), Masanobu Kano1,2)

Department of Neurophysiology, Graduate School of Medicine, The University ofTokyo, Japan, 2WPI-IRCN, UTIAS, The University of Tokyo, Japan1

2P-259Impairment of memory and hippocampal synaptic plasticity inducedby high-fat diet in animal model
Yun-Chi Chang1), Han-Fang Wu1), Ting-Yi Lu1), Yi-Ju Chen1),
Hui-Ching Lin1,2,3)

1
Department and Institute of Physiology, National Yang Ming University, Taiwan, 2Ph.D.
Program for Neural Regenerative Medicine, College of Medical Science and Technology,
Taipei Medical University,Taiwan, 3Brain Research Center, National Yang-Ming
University,Taiwan

2P-260Overexpression of K+ Cl- cotransporter promotes activity dependent
synaptic plasticity and learning
Kayo Nakamura, Junichi Nabekura

Department of Physiological Sciences, National Institute for Physiological Science,Japan

2P-261

Investigating the effects of muscle wasting on Alzheimer’s disease
Ya-Hsin Hsiao, Yung-Shuen Lin, Fang-Yu Lin

Department of Pharmacology, College of Medicine, National Cheng Kung University,
TaiwanNeuroscience: Learning, memory & neuronal plasticity (2)

DAY 3

1
Department of Physiology, Medical Faculty, Universitas Indonesia, Indonesia, 2Centre
de Recherches sur la Cognition Animale, Centre de Biologie Intégrative, Université deToulouse, France , 3Stem Cell Laboratory for CNS Diseases Modeling, Department ofExperimental Medical Science, Wallenberg Neuroscience Center, Lund Stem Cell
Center and MultiPark, Lund University, Sweden

2P-262

HSYA improves cognitive function in MCAO rats via recovering
synaptic plasticity in the hippocampus
Lu Yu1), Yanhong Duan2), Zheng Zhao2), Wendi He2), Ming Xia1),
Qiujuan Zhang3), Xiaohua Cao2)

Comprehensive Department of Traditional Chinese Medicine, Putuo Hospital Affiliatedto Shanghai University of Traditional Chinese Medicine, China, 2Key Laboratory of Brain
Functional Genomics, Ministry of Education, Shanghai Key Laboratory of Brain
Functional Genomics, School of Life Sciences, East China Normal University, China,
3
Department of Neurology, Yueyang Hospital of Integrated Chinese and Western
Medicine Affiliated to Shanghai University of Traditional Chinese Medicine, China
1

2P-263

The response to whisker stimulation in the visual cortex of monoculardeprived mice in vivo
Akari Hashimoto, Akiko Miyamoto, Yoshihisa Tachibana,
Koichiro Haruwaka, Hiroaki Wake
Department of System Neuroscience, University of Kobe, Japan

2P-264

Metabotropic glutamate receptor 5 (mGluR5) has a critical role inbehavioral flexibility
Chul Hoon Kim, Shinwon Kang, Jisoo Lim, Hyun Jong Noh
Pharmacology, Yonsei University College of Medicine, Korea

2P-265

Increase of sleep spindle density induced by rTMS for major depression
Takuji Izuno1,2), Motoaki Nakamura3), Takashi Saeki4), Nobuhide Hirai5),
Mana Tsukada1), Hideshi Ikemoto1), Chiaki Tezuka1), Kana Takahashi1),
Masataka Sunagawa1), Masahiko Izumizaki1)

1
Department of Physiology, School of Medicine, Showa University, Japan, 2Kanagawa
Psychiatric Center, Japan, 3Medical Institute of Developmental Disabilities Research,Showa University Japan, 4Department of Psychiatry, Yokohama City University Schoolof Medicine, Japan, 5Tokyo Medical and Dental University, Japan

2P-266

Speed representation in the hippocampus and entorhinal cortex
Motosada Iwase, Takuma Kitanishi, Kenji Mizuseki

Department of Physiology, Osaka City University Graduate School of Medicine

2P-267Single Purkinje Neuron Voltage Imaging to Detect Cerebellar Parallel
Fibre Long Term Depression
Ruth M Empson1,2), Emmet m Power1), Emma Deeney1), Dan Potapov1),
Kay Potapov1), Thomas Knopfel2)
1

2P-268

University of Otago, New Zealand, 2Imperial College, UK

Hippocampal, amygdala neuronal, and sympathetic nerve activities
in odor-cue fear conditioned rats
Kana Yaguchi, Sizuka Ikegame, Kana Nagao, Misa Yoshimoto, Kenju Miki
Department of Health Science ,University of Nara Woman's University , Japan

2P-269

Two groups of SPNs in cholinergic modulation of corticostriatal
plasticity in dorsomedial striatum
Atsushi Tamura, Kiyoto Kurima, Yumiko Akamine, Jeffery R Wickens

Neurobiology Reserch Unit, Okinawa Institute of Science and Technology, Japan

2P-270Contribution of Thyrotropin-Releasing Hormone to Cerebellar LongTerm Depression and Motor Learning
Masashi Watanabe1), Yasunori Matsuzaki1), Yasuyo Nakajima2),
Atsushi Ozawa2), Masanobu Yamada2), Hirokazu Hirai1)

Neuroscience: Learning, memory & neuronal plasticity (2)1Department of Neurophysiology, Gunma University, Japan, 2Department of Medicine
and Molecular Science, Gunma University, Japan

2P-271

Sharp-wave ripples facilitate memory consolidation via activation ofcAMP
Constantine Pavlides, Jiyeon Cho, Krzysztof A Sypniewski
University of Tsukuba, Japan

2P-272

Real-time dynamism of hippocampal CA1 firings after the 4 different
episodic stimuli
Takuto Tomokage, Junko Ishikawa, Dai Mitsushima

Department of Physiology, Yamaguchi University Graduate School of Medicine, Japan

2P-273

Kyoung-Hye Yoon, Hee Kyung Lee

Department of Physiology, Mitohormesis Research Center, Yonsei University Wonju
College of Medicine, Korea

2P-274

Nitric oxide into the basolateral amygdala potentiates stress-induced
spatial memory disorder in rat
Roya Ranjbar Saber1), Hedayat Sahraei2), Esmaeil Nikkar3),
Hassan Ghoshooni3), Mohammad Hadipour3)

Neurophysiology Research Center, Shahid Beheshti University of Medical Science, Iran,
Neuroscience Research Center, Baqiyatallah University of Medical Science, Iran,3
Department of Physiology and Biophysics, School of Medicine, Baqiyatallah Universityof Medical Science, Iran1
2

Neuroscience: Neurologic and psychiatric diseases (2)★ 2P-276(Y-19)

Characterization of a novel and potent neuronal Kv7/M opener
SCR2682 for anti-epilepsy
Yani Liu1), Fan Zhang2), Feng Tang3), Bo Liang3), Huanming Chen3), Ge Jin4),
Qi Sun5), Hailin Zhang2), Kewei Wang1)
Department of Pharmacology, School of Pharmacy, Qingdao University, China,
Department of Pharmacology, Hebei Medical University, China, 3Medicinal Chemistry,
Simcere Pharmaceuticals, China, 4Department of Pharmacology, Shenyang Medical
College, China, 5Department of Medicinal Chemistry, School of Pharmaceutical
Sciences, Peking University, China
1
2

2P-277(AP-1)

Chronic stress causes excessive aggression by altering synaptic
actin dynamics in the mPFC
Hirobumi Tada1,2), Takuya Takahashi2)
12

2P-278

Section of Neuroendocrinology, National Center for Geriatrics and Gerontology, Japan,
Department of Physiology, Yokohama City University

ASD-like Behaviors and Synaptic Defects Inherit to Subsequent
Generations in VPA-Induced Rat Model
Ming-Chia Chu1), Han-Fang Wu1), Hui-Ching Lin1,2,3)

Department and Institute of Physiology, School of Medicine, National Yang-Ming
University, Taiwan, 2Brain Research Center, National Yang-Ming University, Taiwan, 3Ph.D.
Program for Neural Regenerative Medicine, College of Medical Science and Technology,
Taipei Medical University, Taiwan
1

2P-279The antiseizure activities of new hydrazine derivatives: behavioral
and electrophysiological studies
Elmira Heidarli1), Hamid Irannejad2), Nima Naderi3)

Neuroscience: Learning, memory & neuronal plasticity (2)/Neuroscience: Neurologic and psychiatric diseases (2)DAY 3Understanding the mechanism of odor-specific memory formation in
Caenorhabditis elegans

Department of Toxicology and Pharmacology, PhD student, School of Pharmacy,
Shahid Beheshti University of Medical Sciences, Iran , 2Department of Medicinal
Chemistry, Associate professor, Mazandaran University of Medical Sciences, Iran,3
Department of Toxicology and Pharmacology, Associate professor, School of Pharmacy,
Shahid Beheshti University of Medical Sciences, Iran1

2P-280

Genome-wide screening of genes involved in tau aggregation by
CRIPSR/Cas9 system
Ihori Ebinuma, Yu Nemoto, Takanobu Suzuki, Yukiko Hori, Taisuke Tomita

Laboratory of Neuropathology and Neuroscience, Graduate School of Pharmaceutical
Sciences, University of Tokyo, Japan

2P-281

Berberine attenuated the cytotoxicity induced by t-BHP via inhibiting
oxidative stress and mitophagy
Zhengmao Li

Key Laboratory of Biotechnology and Pharmaceutical Engineering, School of
Pharmaceutical Sciences, Wenzhou Medical University, China

2P-282Chloroquine promotes the recovery of SCI by inhibiting  inflammationand ER stressHongyu Zhang1), Xiaojie Wei2)

Molecular Pharmacology Research Center, School of Pharmaceutical Science,
Wenzhou Medical University, China, 2Department of Orthopaedics, Cixi People’s
Hospital, Wenzhou Medical University, China

1

2P-283

GLYX-13 alleviates chronic stress-induced depression-like behavior
through its actions in midbrain
Yu-Cheng Ho

Department of Medicine, Mackay Medical College, Taiwan

2P-284

Effects of optogenetic inhibition of 5-HT neurons in the dorsal raphe
nucleus on respiratory control

Mitsuko Kanamaru1,2), Mana Tsukada2), Akira Yoshikawa2),
Hiroshi Onimaru2), Ayako Mochizuki3), Masataka Sunagawa2), Tomio Inoue3),
Masahiko Izumizaki2)

1
Physiology, Faculty of Arts and Sciences, Showa University, Japan, 2Department of
Physiology, Showa University School of Medicine, Japan, 3Department of Oral
Physiology, Showa University School of Dentistry, Japan

2P-285

Astrocytic Ca2+ signals via IP3 receptor type2 mediate reactive astrocytes after status epilepticus

Fumikazu Sano1,2), Eiji Shigetomi1), Schuichi Koizumi1), Hideaki Kanemura2),
Katsuhiko Mikoshiba3), Masao Aihara2)

Department of Neuropharmacology, Interdisciplinary Graduate School of Medicine,
University of Yamanashi, Japan, 2Department of Pediatrics, Faculty of Medicine,
University of Yamanashi, Japan, 3Laboratory for Developmental Neurobiology, RIKEN
Brain Science Institute, Japan1

2P-286

CSD is accompanied by mitochondrial oxidaization wave revealedwith Flaboprotein autofluorescence
Hitoshi Maeda, Kohta Terada, Sohta Katohno, Syunichi Kuwana

Department of Physical Therapy, Faculty of Health Sciences, Uekusagakuen University,Japan

2P-287

Impaired olfactory identification in patients with cerebrovasculardiseaseFumino Okutani1), Kazuyuki Omori2)
1

Department of Occupational Health, Kochi Medical School, Japan, 2Matsuyama
Neuroscience: Neurologic and psychiatric diseases (2)Rehabilitation Hospital

2P-288

Physiological characteristics of rhythmic masticatory muscle activity
during sleep in children
Yuki Shiraishi1,2), Masaya Tachibana3), Sheng-Yun Lu3), Ai Shirota1),
Ikuko Mohri3), Shingo Haraki4), Atsuko Tsujisaka4), Masako Taniike3),
Takashi Yamashiro2), Takafumi Kato2)

Department of Oral Physiology, Osaka University Graduate School of Dentistry, Japan,
Department of Orthodontics and Dentofacial Orthopedics, Osaka University Graduate
School of Dentistry, 3United Graduate School of Child Development, Osaka University,
4
Department of Fixed Prosthodontics, Osaka University Graduate School of Dentistry12

2P-289Risa Toyota1,2), Mutsumi Okura1,3), Shigeru Nonoue4,5), Shingo Haraki6),
Akiko Tsujisaka6), Hiroyoshi Adachi4,5,7), Kazunori Ikebe2), Takafumi Kato1)

Department of Oral Physiology, Osaka University Graduate School of Dentistry, Japan,
Department of Prosthodontics, Gerodontology and Oral Rehabilitation, Osaka
University Graduate School of Dentistry, Japan, 3Sleep Medical Center, Osaka Kaisei
Hospital, Japan, 4Sleep Medicine Center, Osaka University Hospital, Japan, 5Departmentof Psychiatry, Osaka University Graduate School of Medicine, Japan, 6Department of
Fixed Prosthodontics, Osaka University Graduate School of Dentistry, Japan, 7Healthand Counseling Center, Osaka University, Japan1
2

2P-290Role of cortico-brainstem circuits in poststroke rehabilitation-induced
functional recovery
Akimasa Ishida1), Takeshi Shimizu1), Naoki Tajiri1), Kenta Kobayashi2),
Tadashi Isa3), Hideki Hida1)1Dept. Neurophysiol. and Brain Sci., Nagoya City Univ. Grad. Sch. Med. Sci., Japan, 2Sec.
Viral Vector Dev, Natl, Inst. Physiol. Sci., Japan, 3Dept. Physiol and Neurobiol., Kyoto Grad
Sch Med., Japan

2P-291The effect of orally-administered baclofen on spinocerebellar ataxia
type 3 (SCA3) model mice
Nobutake Hosoi, Hirokazu Hirai

Department of Neurophysiology and Neural Repair, Gunma University Graduate
School of Medicine, Japan

2P-292

Metabotropic Glutamate Receptor as a potential therapeutic target
for the treatment of SCA1
Mohamed Fasil Ibrahim, Daniil Potapov, Kay Potapov, Ruth M Empson

Department of Physiology, School of Biomedical Sciences, University of Otago, New
Zealand

2P-293

Transgeneration of environmental chemicals-primed rat hyperactivity
Masami Ishido

Center for Environ Risk Res, Natl Inst Environ Studies, Japan

2P-294Social isolation during developmental critical window affects inhibitory
neuronal circuitsin mPFC
Hiroki Yoshino1), Kazuhiko Yamamuro1), Yoichi Ogawa2),
Manabu Makinoda1), Yasuhiko Saito2), Toshifumi Kishimoto1)

Department of Psychiatry, Nara Medical University, Japan, 2Department of Physiology 1,
Nara Medical University
1

2P-295

The 40Hz-ASR may be a good predictor of conscious outcome inpatients with severe head injury
Shun-ichiro Hirano

Neuroscience: Neurologic and psychiatric diseases (2)DAY 3Masseter muscle activity during REM sleep in young adults withsleep bruxismDepartment of Physiology, Osaka Dental University, Japan

2P-296

Deep brain stimulation for depression in rats: correction of left/righthemispheric imbalance
Yukitoshi Sakaguchi, Yoshio Sakurai

Graduate School of Brain Science, Doshisha University, Japan

2P-297

Experience and cell type-dependent induction of MeCP2 in the visualthalamusYuki Yagasaki, Goichi Miyoshi, Mariko Miyata

Department of Physiology, Division of Neurophysiology, School of Medicine, Tokyo
Women's Medical University, Japan

2P-298Function of the primate medial frontal cortex in the control of moodand affect: an rTMS study
Shinya Nakamura, Ken-Ichiro Tsutsui

Laboratory of Systems Neuroscience, Graduate School of Life Sciences, Tohoku
University, Japan

Neuroscience: Somatosensory & Pain (2)2P-299Inflammatory pain changes the electrophysiological properties oflocus coeruleus neurons
Fatemeh Farahani, Hossein Azizi, Saeed Semnanian

Department of Physiology, Faculty of Medical Sciences, Tarbiat Modares University, Iran

2P-300Widespread Hyperalgesia and Autonomic Dysregulation in a Rat
Model of Chronic Back Pain
Ryota Tokunaga1,2), Harumi Hotta4), Nobuhiro Watanabe4), Sara Touj1,2),
Hugues Leblond2,3), Mathieu Piché1,2)

1
Department of Chiropractic, Université du Québec à Trois-Riviéres, Canada, 2CogNAC
Research Group, Université du Québec à Trois-Riviéres, Canada, 3Department of
Anatomy, Université du Québec à Trois-Riviéres, Canada, 4Department of Autonomic
Neuroscience, Tokyo Metropolitan Institute of Gerontology, Japan

2P-301

TRPA1 mediates the uterine PGE2-induced cross-organ reflex
sensitizationin anesthetized rats
Tzer-Bin Lin

Department of Physiology, Taipei Medical University, Taiwan

2P-302

Inhibitory effects of Sake lees (Sake Kasu) on stress-induced hyperalgesia in the rats
Shiho Shimizu1,2), Yoshito Kakihara3,4), Mayumi Taiyoji5), Yosuke Nakatani1,2),
Masayuki Kurose1), Nobuyuki Ikeda2), Makio Saeki3), Ritsuo Takagi2),
Kensuke Yamamura1), Keiichiro Okamoto1)

Division of Oral Physiology, Niigata University Graduate School of Medical and Dental
Sciences, Japan, 2Division of Oral and Maxillofacial Surgery, Niigata University Graduate
School of Medical and Dental Sciences, Japan, 3Division of Dental Pharmacology,
Niigata University Graduate School of Medical and Dental Sciences, Japan, 4Departmentof Sakeology, Niigata University, Japan, 5Food Research Center, Niigata Agricultural
Research Institute, Japan1

2P-303

Renin-angiotensin system and angiotensin II receptors in rat geni­
culate ganglion
Takeshi Suwabe, Toshiaki Yasuo, Noritaka Sako

Department of Oral Physiology, School of Dentistry, Asahi University, Japan

Neuroscience: Neurologic and psychiatric diseases (2)/Neuroscience: Somatosensory & Pain (2)2P-304

Inhibitory effect of bee venom on the reserpine-induced pain anddepression-like behavior in mice
Jae-Gyun Choi1), Dong-Wook Kang1), Cuk-Seong Kim2), Sang Do Lee2),
Byeong Hwa Jeon2), Jin Bong Park1), Hyun-Woo Kim1)

Department of Physiology and Medical Science, Brain Research Institute, College ofMedicine, Chungnam National University, Republic of Korea, 2Department of Physiology
and Medical Science, Research Institute of Medical Science, College of Medicine,
Chungnam National University, Republic of Korea
12P-305Distribution of HCN4 positive cell in mouse spinal dorsal horn
Taku Nakagawa1), Toshiharu Yasaka2), Noriyuki Nakashima1),
Makoto Takano1)

2P-306

Response properties of premotor heat-sensitive neurons in awake
behaving monkeys
Shumpei Unno1), Masamichi Shinoda2), Koichi Iwata2)

Department of Oral Physiology, Matsumoto Dental University, Japan, 2Department of
Physiology, School of Dentistry, Nihon University, Japan1★ 2P-307(Y-20)

Molecular mechanism of dopamine-induced itch in mice
YoungIn Choi1), PyungSun Cho1,2), HanKyu Lee1), SungJun Jung1)
1
Department of Biomedical Science, Hanyang University, Korea, 2Department of
Physiology, Korea University, Republic of Korea

2P-308

Negative modulation of TRPV1 by alpha 2 adrenergic receptor
agonist, Dexmedetomidine
Byeong-min Lee1,3), Yoonsun Jang1), Yong Ho Kim4), Chul-kyu Park4),
Teo Jeon Shin2), Gehoon Chung1,3)

Department of Oral Physiology and Neurobiology, School of Dentistry, Seoul National
University, Korea, 2Department of Pediatric Dentistry, School of Dentistry, Seoul
National University, Republic of Korea, 3Dental Research Institute, Seoul National
University, Republic of Korea, 4Department of Physiology, Gachon University, Republicof Korea1

2P-309Direct Mechanical stimulation evoked Gd3+-sensitive inward current
in trigeminal ganglion neurons
Asuka Higashikawa1), Maki Kimura1), Miyuki Shimada1), Hidetaka Kuroda3),
Wataru Ofusa1), Sadao Ohyama 1,2), Masayuki Ando1), Kyousuke Kono1),
Hiroyuki Mochizuki1), Yoshiyuki Shibukawa1)

Department of Physiology, Tokyo Dental College, Japan, 2Department of Oral Surgery,Tokyo Metropolitan Komagome Hospital, 3Department of Critical Care Medicine andDentistry, Division of Anesthesiology, Kanagawa Dental University

1

2P-310ASIC 3 contributes to mechanical hypersensitivity in the rat model ofcold exposed osteoarthritis
Sungtae Koo1,2,3), So-Hee Kim3,4), Byeong Uk Ji1,3), Ji Eun Lee3)

Department of Korean Medical Science, School of Korean Medicine, Pusan National
University, Korea, 2Division of Meridian and Structural Medicine, School of Korean
Medicine, Pusan National University, 3Healthy Aging Korean Medical Research Center,
School of Korean Medicine, Pusan National University, 4Institute of Korean Medical
Science, School of Korean Medicine, Pusan National University

1

2P-311

Increased transport of spinal l-lactate from astrocytes causes
mechanical hyperlageisa via PKA
Neuroscience: Somatosensory & Pain (2)

DAY 3

1
Department of Physiology, Kurume University, Japan, 2Department of Immunology,
Graduate School of Medical and Dental Sciences, Kagoshima University, Japan

Masahiro Ohsawa, Keisuke Miyamoto, Kei-ichiro Ishikura, Kazuhiko Kume
Department of Neuropharmacology, Nagoya City Univeristy, Japan

2P-312

Neuronal representation in the S1 cortex during formalin-induced
spontaneous pain in mice
Heera Yoon1), Yoo Rim Kim2), Sa-Yoon Park3), Chang-Eop Kim3),
Geehoon Chung1), Sang Jeong Kim2), Sun Kwang Kim1)
1
2
3

2P-313

Department of Physiology, College of Korean Medicine, Kyung Hee University, Korea,
Department of Physiology, College of Medicine, Seoul National University, Korea ,Department of Physiology, College of Korean Medicine, Gachon University, Korea

Effects of Cinnamic Acid on Chemotherapy-Induced Peripheral
Neuropathy
Hyeonkyeong Chae, Woojin Kim, Sun Kwang Kim

Department of Physiology, College of Korean Medicine, Kyung Hee University, Korea

2P-314

Effect of Bee Venom Derived Phospholipase A2 on Nerve InjuryInduced Neuropathic Pain
Seunghui Woo, Geehoon Chung, Sun Kwang Kim

Department of Physiology, College of Korean Medicine, Kyung Hee University, Korea

2P-315

EP4 receptor-mediated augmentation of Ih currents in Abeta DRG
neurons underlies neuropathic pain
Mitsuhiko Yamada1), Hao Zhang1,2), Toshihide Kashihara1),
Tsutomu Nakada1), Satoshi Tanaka2), Kumiko Ishida2), Satoshi Fuseya2),
Hiroyuki Kawagishi1), Kenkichi Kiyosawa1,2), Mikito Kawamata2)

Department of Molecular Pharmacology, Shinshu University School of Medicine,Japan, 2Department of Anesthesiology and Resuscitology, Shinshu University School of
Medicine, Japan1

2P-316

Effects of Venlafaxine on Oxaliplatin and Paclitaxel Induced Neuropathic Pain in Mice
Daxian Li1,2), Woojin Kim1), Sun Kwang Kim1)
12

2P-317

Department of Physiology, College of Korean Medicine, Kyung Hee University, Korea,
Department of Science in Korean Medicine,Graduate School, Kyung Hee University

Plastic changes in cortical excitatory responses in the model rat with
infraorbital nerve ligation
Manabu Zama1,2), Masayuki Kobayashi2), Morio Tonogi1),
Tadayoshi Kaneko1)

1
Department of Oral and Maxillofacial Surgery, University of Nihon, Japan, 2Departmentof Pharmacology, University of Nihon, Japan

2P-318Perineural expression of TNF-α contributes to long-term mechanicalallodynia in CRPS model mice
Shiho Shibata1,2), Hideaki Tagashira1), Satomi Kita1,3), Tomo Kita1),
Sari Suzuki1), Ken Yamaura2), Takahiro Iwamoto1)

Department of Pharmacology, Faculty of Medicine, Fukuoka University, Japan,
Department of Anesthesiology, Faculty of Medicine, Fukuoka University, Japan,
3
Department of Pharmacology, Faculty of Pharmaceutical Sciences, Tokushima Bunri
University, Japan1
2

2P-319

Acute nociceptive stimuli induce the activity of serotonin andnoradrenalin neurons in awake mice
Akira Yamashita1), Shunpei Moriya1), Ryusei Nishi1), Yoko Ikoma1),
Akihiro Yamanaka2), Tomoyuki Kuwaki1)
1

Department of Physiology 1, Graduate School of Medical and Dental Sciences,
Neuroscience: Somatosensory & Pain (2)Kagoshima University, Japan, 2Department of Neuroscience 2, Research Institute ofEnvironmental Medicine, Nagoya University, Japan

2P-320Effects of naftopidil in substantia gelatinosa neurons of the rat spinal
dorsal horn
Daisuke Uta1), Tsuyoshi Hattori2), Megumu Yoshimura3,4)

Department of Applied Pharmacology, Graduate School of Medicine andPharmaceutical Sciences, University of Toyama, Japan, 2Asahi Kasei Pharma Co., Japan,
Graduate School of Health Sciences, Kumamoto Health Science University, Japan,
4
Nogata Nakamura Hospital, Japan1

3

2P-321

Profiles of excitatory projection from the insular cortex to trigeminal
spinal subnucleus caudalis
Yuka Nakaya, Kiyofumi Yamamoto, Masayuki Kobayashi

2P-322Dexmedetomidine inhibits voltage-gated sodium channels intrigeminal ganglion neurons
Chul-Kyu Park, Sang-Taek Im, Ki Whan Kim, Joong Soo Kim, Yong Ho Kim

Gachon Pain Center and Department of Physiology, College of Medicine, Gachon
University, Korea

2P-323In vivo Ca2+ imaging of somatosensory cortex in postoperative andinflammatory pain models of mice
Takuya Okada1,2,3), Yoshihisa Tachibana1,3), Yuki Nomura2), Norihiko Obata2),
Satoshi Mizobuchi2), Hiroaki Wake1,3)

Department of System Neuroscience, Kobe University Graduate School of Medicine,Japan, 2Department of Anesthesiology, Kobe University Graduate School of Medicine,
CREST, JST

1

3

2P-324

Alteration of spinal sensory processing from the LUT in rats withstreptozotocin-induced diabetes
Tatsuki Nakagawa1,2,3), Atsushi Hakozaki2), Nozomi Akimoto2),
Noriyuki Ozaki3), Masahito Kawatani4), Keiji Imoto2), Hidemasa Furue1,2)

1Department of Neurophysiology, Hyogo College of Medicine, Japan, 2Department ofInformation Physiology, National Institute for Physiological Sciences, Japan,
3
Department of Functional Anatomy, Graduate School of Medicine, Kanazawa
University, Japan, 4Department of Neurophysiology, Graduate School of Medicine,
Akita University, Japan

2P-325

Effects of ethanol on nociceptive synaptic transmission in the rat
spinal dorsal horn
Akihiro Yamada1,2,3), Kohei Koga1), Kazuhiko Kume3), Masahiro Ohsawa3),
Keiji Imoto2), Hidemasa Furue1,2)

1Department of Neruophysiology, Hyogo College of Medicine, Japan, 2Department ofInformation Physiology, National Institute for Physiological Sciences, Japan,
3
Department of Neuropharmacology, Nagoya City University, Japan

Neuroscience: Autonomic physiology (2)2P-326

Dexmedetomoidine suppresses rat nodose ganglion tetrodotoxinresistant voltage-gated sodium current
Ryoji Ide, Kosuke Iwasaki, Chikako Saiki, Toshio Imai, Shigeji Matsumoto

Depertment of Physiology, Nippon Dental University, School of Life Dentistry at Tokyo,
Japan

Neuroscience: Somatosensory & Pain (2)/Neuroscience: Autonomic physiology (2)DAY 3

Department of Pharmacology, Nihon University School of Dentistry, Japan

2P-327

Expression of c-Fos and the cardiovascular response evoked by anodor fear stressor in the rat
Seita Hori, Ena Yamamoto, Jouji Horiuchi

Department of Biomedical Engineering, Toyo University, Japan

2P-328Does listening to Mozart’s or Bach’s music have any effects on
autonomic nervous activity?
Junko Hoshi, Xinru Sun, Hiromasa Tanno, Emi Kanno, Ryoko Maruyama

Department of Health Sciences, Tohoku University Graduate School of Medicine, Japan

2P-329Effects of GABA agonist injection into the ventrolateral medulla onoropharyngeal swallowing
Shinya Fuse1,2), Yoichiro Sugiyama2), Rishi Dhingra3),
Mathias Dutschmann 3), Shigeru Hirano2), Yoshitaka Oku 1)

1
Department of Physiology, Hyogo College of Medicine, Japan, 2Department ofOtolaryngology-Head and Neck Surgery, Kyoto Prefectural University of Medicine,Japan, 3Florey Institute of Neuroscience and Mental Health, Australia

2P-330

Coordinated involvement of the amygdala and claustrum for bloodpressure control during exercise
Ko Yamanaka, Jimmy Kim, Hidefumi Waki

Department of Physiology, Health and Sports Science, Juntendo University, Japan

2P-331

Hormonal secretion from the thyroid gland is promoted by mechanicalstimulation of the pharynx
Kaori Iimura, Harue Suzuki, Harumi Hotta

Department of Autonomic Neuroscience, Tokyo Metropolitan Institute of Gerontology,Japan

2P-332

Exercise improve stress-induced high blood pressure and abnormal
gene expression in the amygdala
Keisuke Tomita1), Ko Yamanaka1), Kei Tsukioka1), Makoto Suzuki1),
Linh Pham2), Sabine S. Gouraud2), Hidefumi Waki1)

Graduate School of Health and Sports Science, Juntendo University, Japan,
Department of Biology, Ochanomizu University, Japan1
2

2P-333Ethanol injection differently activated autonomic nerve activity inanesthetized rats
Chen Fu1,2), Tanida Mamoru1)

1
Physiology 2, Kanazawa Medical University, Japan, 2General Surgery Department, theFourth Affiliated Hospital of China Medical University, China

2P-334Estradiol-dependent gene expression profile in the amygdala ofovariectomized SHRs
Linh Thuy Pham1,2), Onishi Makiko1,4), Yamanaka Ko5),
Miyamoto Yasunori1,2,4), Waki Hidefumi5), Gouraud Sabine2,3)1
Graduate School of Humanities and Sciences, Ochanomizu University, Japan, 2Grad
Sch General Educational Research, Ochanomizu University, Japan, 3Dept. Biology,
Ochanomizu University, Japan, 4Institute of Human Life Innovation, Ochanomizu
University, Japan, 5Dept. Physiology, Grad Sch Health and Sports Science, Juntendo
University, Japan

2P-335

Discharge activities of diaphragm motor units during inspiratory load
Ryosuke Takei1), Kenta Kawamura1), Yukako Sedaka1), Kazumasa Sasaki2),
Seiichi Sasaki3), Kazuhide Tomita1)
1

Ibaraki Prefectual University of Heaith Science,Japan, 2Toho University, Japan, 3Toyo
Neuroscience: Autonomic physiology (2)Public Health College, Japan

2P-336

A role of TRPA1 in oxygen detection

Sichong Chen1,2), C. Kuroki1), N. Takahashi1,3), Ly. Hao2), Y. Mori3),
T. Kuwaki1)
Department of Physiology, Kagoshima University Graduate School of Medical and
Dental Sciences, Japan, 2Department of Pharmaceutical Toxicology, China Medical
University School of Pharmacy, China, 3 Department of Synthetic Chemistry andBiological Chemistry, Graduate School of Engineering, Kyoto University, Japan1

2P-337

Descending inhibition on spinal seizure-like activity in the phrenic
nerve output
Shih Tien Lin

Department of Physiology, Showa University School of Medicine, Japan

Measurement of paraventricular nucleus neuronal and sympathetic
nerve activities in conscious rats
Shizuka Ikegame, Misa Yoshimoto, Kenju Miki

Department of Health science, Nara Women's University, Japan

2P-339Projection from the midbrain to the rostroventral medulla and the
cardiovascular response to stress
Mio Matsuyama, Ena Yamamoto, Jouji Horiuchi

Department of Biomedical Engineering, Toyo University, Japan

2P-340Gut hormone signal alters lick microstructure and taste reactivity tosweet stimulation in mice
Yasunobu Yasoshima, Erina Yamaguchi

Division of Behavioral Physiology, Graduate School of Human Sciences, Osaka
University, Japan

2P-341

Hyposalivation and impaired parasympathetic vasodilation in parotid
glands with diabetes mellitus
Toshiya Sato, Kohei Mito, Hisayoshi Ishii

Division of Physiology, Department of Oral Biology, School of Dentistry, Health Sciences
University of Hokkaido, Japan

2P-342

Acute myocardial infarction activates hypothalamic vasopressin andoxytocin neurons
Colin Hamilton Brown, Ranjan K Roy, Rachael A Augustine,
Daryl O Schwenke
Department of Physiology, University of Otago, New Zealand

Neuroscience: Others (2)2P-343

Phospholipase C-related inactive protein type-1 deficiency alters
propofol-induced EEG activity
Yoshikazu Nikaido1,2), Tomonori Furukawa2), Shuji Shimoyama2),
Yoshiki Ogata2), Tetsuya Kushikata1), Kazuyoshi Hirota1), Masato Hirata3,4),
Takashi Kanematsu5), Shinya Ueno2)

1
Department of Anesthesiology, Hirosaki University, Japan, 2Department of
Neurophysiology, Hirosaki University, Japan, 3Laboratory of Molecular and Cellular
Biochemistry, Faculty of Dental Science, Kyushu University, Japan, 4Fukuoka Dental
College, Japan, 5Department of Cellular and Molecular Pharmacology, Division of BasicLife Sciences, Institute of Biomedical and Health Sciences, Hiroshima University, Japan

Neuroscience: Autonomic physiology (2)/Neuroscience: Others (2)DAY 3

2P-338

2P-344

A microsensing system for the in vivo real-time detection of local drug
kinetics and dynamics
Genki Ogata1), Kai Asai2), Seishiro Sawamura1), Madoka Takai3),
Hiroyuki Kusuhara4), Yasuaki Einaga2), Hiroshi Hibino1)

Dept Mol Physiol, Sch Med, Niigata Univ, Japan, 2Dept of Chem, Fac of Sci and Tech,
Keio Univ, Japan, 3Dept of Bioeng, Grad Sch of Eng, Univ of Tokyo, Japan, 4Lab of Mol
Pharmacokinet, Grad Sch of Pharmaceut Sci, Univ of Tokyo, Japan1

2P-345Treatment of Alzheimer’s disease by a disease-modifying small
molecule
Ya Ke, Xiao Man Zhang, Sheng Xi Yang, Ming Dao Mu, King Lin Rong,
Wing Ho Yung
School of Biomedical Sciences, The Chinese University of Hong Kong

2P-346

Andrographolide relieved pain generated by post-operative pain
model in rat
Meng-Jen Lee1), Yilo Lin2), Siendong Huang 3)

Department of Applied Chemistry, Chaoyang University of Technology, Taiwan,
Graduate Institute Veterinary Pathobiology, National Chung Hsing University, Taiwan,
3
Department of Applied Mathematics, National Dong Hwa University
1
2

2P-347Comparing the natural and morphine induced reward in conditioning
place preference paradigm
Shoele Jamali, Abbas Haghparast

Neuroscience Research Center, Shahid Beheshti University of Medical Sciences, Iran

2P-348

Mouse strain-dependent BBB (blood-brain barrier) permeability of
AAV-PHP.B
Yasunori Matsuzaki, Masami Tanaka, Sachiko Hakoda, Tatsuki Masuda,
Ryota Miyata, Ayumu Konno, Hirokazu Hirai
Department of Neurophysiology and Neural Repair, Gunma university, Japan

2P-349A coagulation factor IX peptide regulates endothelial barrier functionin brainYuusuke Fujiwara1), Hisataka Kitano1,2), Chiaki Hidai2), Shinichiro Kokubun2)

1
Division of Dental Surgery, Nihon University School of Medicine, Japan, 2 Division of
Physiology, Nihon University School of Medicine

2P-350Fatty acid-responding neurons in mouse glossopharyngeal nerve
Keiko Yasumatsu1), Shusuke Iwata1), Mayuko Inoue1), Yuzo Ninomiya1,2)

Division of Sensory Physiology, Research and Development Center for Taste and Odor
Sensing, Kyushu University, Japan, 2Monell Chemical Senses Center, Philadelphia, PA,USA
1

2P-351

The role of HCN4-positive cells in the gastrointestinal development
and motility of zebrafish
Kensuke Fujii1), Koichi Nakajyo2,3), Koichi Kawakami4), Yoshihiro Egashira2),
Yasuhiro Yamamoto2), Kohei Tanigushi1), Masaru Kawai1),
Hideki Tomiyama1), Kazuhisa Uchiyama1), Fumihito Ono2),

Department of General and Gastroenterological Surgery, Osaka Medical College,
Japan, 2Department of Physiology, Division of Life Sciences, Osaka Medical College,
Japan, 3Division of Integrative Physiology, Department of Physiology, Jichi Medical
University, Japan, 4Division of Molecular and Developmental Biology, National Instituteof Genetics, Japan1

Neuroscience: Others (2)2P-352

NHEJ and BER are Concurrently Engaged by APE1 in Oxidative
DNA Damage Repair in Rat Cortical Neurons
Jenq-Lin Yang1), Shu-Fang Sun1), Yun-Ru Yang1), Shang-Der Chen1,2)Institute for Translational Research in Biomedicine, Kaohsiung Chang Gung Memorial
Hospital, Taiwan, 2Department of Neurology, Kaoshiung Chang Gung Memorial
Hospital

1

2P-353

Remote control of neuronal function using X-ray

Takanori Matsubara1,2), Shin-Ichiro Horigane3,4), Shuhei Ueda3,4),
Sayaka Takemoto-Kimura3,4,6), Noriaki Kawaguchi5), Takayuki Yanagida5),
Akihiro Yamanaka1,2,7), Takayuki Yamashita1,2,6,7)

Department of Neuroscience II, Research Institute of Environmental Medicine, Nagoya
University, Japan, 2Department of Neural Regulation, Graduate School of Medicine,
Nagoya University, Japan, 3Department of Neuroscience I, Research Institute ofEnvironmental Medicine, Nagoya University, Japan, 4Department of Molecular
Neuroscience, Graduate School of Medicine, Nagoya University, Japan, 5Graduate
School of Materials Science, Nara Institute of Science and Technology, Japan, 6PRESTO,
Japan Science and Technology Agency, Japan, 7CREST, Japan Science and Technology
Agency, Japan
1

Development of lentiviral vectors for glutamatergic-selective gene
expression in cultured neurons
Yoshihiro Egashira1,2), Yasunori Mori2), Yuchio Yanagawa3),
Shigeo Takamori2)

1
Department of Physiology, Osaka Medical College, Japan, 2Graduate School of Brain
Science, Doshisha University, 3Graduate School of Medicine, Gunma University

2P-355

Effects of Cigarette Smoking on the motor nerve conduction study
parameters among young adults
Rama Mohammed Baba Musa1), Lamis Kaddam1), Mustafa Abdelrahman 1),
Humeda Suekit 2)
1

2P-356

Al-Neelain University faculty of Medicine, Sudan, 2International University of Africa

Dysregulated microRNA expression profiles in extracellular vesicles
of schizophrenia
Kittima Lekmanee1,2), Woraphat Ratta-Apha3), Chanatip Metheetrairut4),
Wittawin Worakitchanon1,2), Pholphat Losatiankij5), Natini Jinawath6),
Witchuda Saengsawang1,2), Arthit Chairoungdua1,2,7)

1
Department of Physiology, Faculty of Science, Mahidol University, Thailand, 2Excellent
Center for Drug Discovery (ECDD), Mahidol University, Thailand, 3Department of
Psychiatry, Faculty of Medicine Siriraj Hospital, Mahidol University, Thailand,
4
Department of Biochemistry, Faculty of Medicine Siriraj Hospital, Mahidol University,
Thailand, 5Somdet Chaopraya Institute of Psychiatry, Thailand, 6Program in Translational
Medicine, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Thailand,
7
Toxicology Graduate Program, Faculty of Science, Mahidol University, Thailand

2P-357

Oral capsaicin sensitivity and preference for spicy food in Japanese
medical students
Yoshihiro Murata1), Kiwamu Shibano1), Masahiro Yamaguchi1),
Fumino Okutani1,2)

1
Department of Physiology, Kochi Medical School, Japan, 2Department of Occupational
Health, Kochi Medical School, Japan

2P-358Hypnotic and anti-inflammatory actions of bromovalerylurea

Haruna Takeda, Naoto Seo, Kohdai Fujita, Arisa Sato, Nanako Kihara,
Me Choudhury, Hajime Yano, Junya Tanaka
Neuroscience: Others (2)DAY 3

2P-354

Department of Molecular and Cellular Physiology, Graduate School of Medicine, Ehime
University, Japan

2P-359Memantine selectively ameliorates gait impairment to hyperalgesia in
MPTP-injected miceRamesh Sharma1,2), Chiranjivi Neupane1,2)

1Department of medical sciences, Chungnam National University, Korea, 2Department
of BK21plus CNU Integrative Biomedical Education Initiative, Korea

2P-360Physiologic process before rhythmic jaw movements after ketamine
injections in guinea pigs
Takafumi Kato1), Yutaka Matsuura1), Hiroshi Yano3), Makoto Higashiyama1),
Hiroki Toyoda1), Ayano Katagiri1), Hajime Sato1), Narikazu Uzawa3),
Atsushi Yoshida2)

Department of Oral Physiology, Osaka University Graduate School of Dentistry, Japan,
Department of Oral Anatomy and Neurobiology, Osaka University Graduate School of
Dentistry, Japan, 3Department of Oral & Maxillofacial Surgery II, Osaka University
Graduate School of Dentistry, Japan1
2

2P-361

Mitochondrial disease diagnosis by urinary tRNA modification analysis
Tetsuya Watanabe1,2), Kazuhito Tomizawa1), Fanyan Wei1), Yukio Ando2)

Department of Molecular Physiology, Graduate School of Medical Sciences, Kumamoto
University, Japan, 2Department of Neurology, Graduate School of Medical Sciences,
Kumamoto University
1

2P-362Age-related changes in hemodynamics and their mechanisms in theorofacial area
Kohei Mito1), Toshiya Sato1), Hisayoshi Ishii1)Div. of Physiol., Dept. of Oral Biol., Sch. of Dent., Health Sci. Univ. of Hokkaido, Japan1

2P-363

Proteomic analysis of the transport system in a connective tissue ofthe mammalian cochlea
Seishiro Sawamura1), Yoriko Nonomura1,2), Fumiaki Nin1), Arata Horii2),
Sugata Takahashi2), Shushi Nagamori3), Yoshikatsu Kanai4), Hiroshi Hibino1)

Department of Molecular Physiology, Niigata University School of Medicine, Japan,
Department of Otorhinolaryngology-Head and Neck Surgery, Niigata University
School of Medicine, Japan, 3Department of Collaborative Research for Bio-Molecular
Dynamics, Nara Medical University, Japan, 4Department of Pharmacology, Graduate
School of Medicine, Osaka University, Japan1
2

2P-364

Rodent posterior parietal cortex controls ipsilateral as well con­tralateral movement
Shogo Soma1), Junichi Yoshida2), Shigeki Kato3), Satoshi Nonomura2),
Yae K Sugimura4), Alain Rios2), Masanori Kawabata2), Kazuto Kobayashi3),
Fusao Kato4), Yutaka Sakai2), Yoshikazu Isomura2)

1
Department of Anatomy and Neurobiology University of California, 2Brain Science
Institute, Tamagawa University, 3Department of Molecular Genetics, Institute of
Biomedical Sciences, Fukushima Medical University School of Medicine, 4Departmentof Neuroscience, The Jikei University School of Medicine

2P-365Development of a Low-cost, Comprehensive Recording System for
Circadian Rhythm Behavior
Jea Kwon Kwon, Changjoon Justin Lee

Korea Institute of Science and Technology, Korea

Neuroscience: Others (2)★ 2P-366(Y-21)

Molecule REST interacts with brain 5-HT system in tilapia fish
during social stress
Shingo Nakajima, Tomoko Soga, Ishwar S Parhar★ 2P-367(Y-22)

Brain Research Institute Monash Sunway (BRIMS), School of Medicine and Health
Sciences, Monash University Malaysia

Altered electrical responsiveness of CA1 pyramidal neurons in avalproic acid rat model of autism
Mona Rahdar, Razieh Hajisoltani, Shima Davoudi, Narges Hosseinmardi,
Mahyar Janahmadi(Y-23)

Lumbrokinase improves neurological deficit by preventing endo­
plasmic reticulum stress
Yi Hsin Wang1), Hsing Hui Su2), Jiuan Miaw Liao3), Shiang Suo Huang4)★ 2P-369(Y-24)

1
Institute of Medicine, Chung Shan Medical University, Taiwan, 2Department andInstitute of Pharmacology, School of Medicine, National Yang-Ming University, Taiwan,
3
Department of Physiology, Chung Shan Medical University and Chung Shan Medical
University Hospital, Taiwan, 4Department of Pharmacology and Institute of Medicine,
Chung Shan Medical University, and Department of Pharmacy, Chung Shan Medical
University Hospital, Taiwan

Oxytocin effects on nicotine aversion and anxiety in nicotineexposed early adolescent rats
Minji Jang, Taesub Jung, Jihyun Noh★ 2P-370(Y-25)

Department of Science education, University of Dankook, South Korea

Mesenchymal stem cell conditioned medium therapy modulates
neuroinflammatory symptoms
Vida Nazemian, Jalal Zaringhalam★ 2P-371(Y-26)

Physiology Department, Shahid Beheshti University of Medical Sciences

Depolarized subicular microcircuits mediate generalized seizure intemporal lobe epilepsy
Yi Wang, Cenglin Xu, Zhenghao Xu, Caihong Ji, Ying Wang, Shuang Wang,
Xiaoming Li, Zhong Chen

★ 2P-372(Y-27)

School of Medicine, Zhejiang University, China

Mitochondrial fission inhibitor attenuates brain mitochondrial
dysfunction in pre-diabetic rats
Siripong Palee1,2), Chayodom Maneechote1,2,3), Nattayaporn Apaijai1,2),
Thidarat Jaiwongkam1,2), Sasiwan Kerdphoo1,2), Nipon Chattipakorn1,2,3),
Siriporn C Chattipakorn1,2,4)
Cardiac Electrophysiology Research and Training Center, Faculty of Medicine, Chiang
Mai University, Thailand, 2Center of Excellence in Cardiac Electrophysiology Research,
Chiang Mai University, Thailand, 3Cardiac Electrophysiology Unit, Department of
Physiology, Faculty of Medicine, Chiang Mai University, Thailand, 4Department of Oral
Biology and Diagnostic Sciences, Faculty of Dentistry, Chiang Mai University, Thailand
1

2P-373

Effects of vagotomy and area postrema lesion on induction of emesisby emetine
Makoto Funahashi, Yoshiyuki Hirai, Mayu Fujita, Kazunari Hisadome,
Hitoshi Maezawa

Oral Physiology, Department of Oral Functional Science, Faculty of Dental Medicine
and Graduate School of Dental Medicine, Hokkaido University
Neuroscience: Others (2)DAY 3★ 2P-368

Neuroscience Research Center and Dept. of Physiology, Medical School, Shahid
Beheshti University of Medical Sciences, Iran

Epithelial Transport, Secretion & Absorption: Epithelium (2)2P-374

Kampo medicine Junchoto promotes intestinal Cl-/water secretion bycAMP-dependent CFTR activation
Tomohiro Numata1), Kaori Sato-Numata2), Yasunobu Okada3), Ryuji Inoue1)

Department of Physiology, Graduate School of Medical Sciences, Fukuoka University,
Japan., 2Japan Society for the Promotion of Science, Japan., 3Department of Physiology
and Systems Bioscience, Kyoto Prefectural University of Medicine, Japan1

2P-375

CFTR function and CFTR mutations of cystic fibrosis in Japan

Yuka Kozawa1), Akiko Yamamoto1), Miyuki Nakakuki1), Kotoyo Fujiki2),
Shiho Kondo3), Itsuka Taniguchi1), Satoru Naruse4), Hiroshi Ishiguro1)

Department of Human Nutrition, Nagoya University Graduate School of Medicine,
Department of Nutritional Sciences, Nagoya University of Arts and Sciences,
Department of Food Science and Nutrition, Nagoya Women's University, 4Miyoshi
Municipal Hospital1
2
3

2P-376

Characterization of the Most Frequent Cftr-Mutant Found in JapaneseCystic Fibrosis Patients
Yoshiro Sohma1,2), Kanako Wakabayashi-Nakao1), Yingchun Yu2),
Miyuki Nakakuki3), Tzyh-Chang Hwang2), Hiroshi Ishiguro3)

Department of Pharmaceutical Sciences, International University of Health andWelfare, Japan, 2John M Dalton Cardiovascular Research Center, University of MissouriColumbia, USA, 3Department of Human Nutrition, Nagoya University Graduate Schoolof Medicine, Japan1

2P-377

Non-morphogenic function of Sonic Hedgehog as a negative
regulator of gastric H+,K+-ATPase
Takuto Fujii, Siriporn Phutthatiraphap, Takahiro Shimizu, Hideki Sakai

Department of Pharmaceutical Physiology, Graduate School of Medicine andPharmaceutical Sciences, University of Toyama, Japan

2P-378

Aldosterone action on epithelial Na+ channel trafficking under   theinsulin-stimulated condition
Rie Marunaka1), Yoshinori Marunaka1,2,3)

Department of Molecular Cellular Physiology, Kyoto Prefectural University of Medicine,Research Institute for Clinical Physiology, Kyoto Industrial Health Association, 3ResearchCenter for Drug Discovery and Pharmaceutical Development Science, Research
Organization of Science and Technology, Ritsumeikan University
1
2

2P-379Loss of ezrin causes impaired proximal tubular solute reabsorption in
the kidney
Ryo Hatano1), Mikiko Takayama2), Kotoku Kawaguchi2), Toru Kimura3),
Toshiyuki Fukutomi3), Hiroyuki Sakurai3), Takashi Miki1), Shinji Asano2)

Department of Medical Physiology, Chiba University Graduate School of Medicine,
Department of Molecular Physiology, College of Pharmaceutical Sciences, Ritsumeikan
University, 3Department of Pharmacology and Toxicology, Korin University School of
Medicine
1
2

2P-380Inhibition of prostaglandin E2-induced Cl- secretion by dihydro­
pyrazole derivatives in rat colon
Hideki Sakai1), Nozomi Murata1), Kenji Sugimoto2), Yuka Miura2),
Takahiro Shimizu1), Takuto Fujii1), Yuji Matsuya2)

1
Department of Pharmaceutical Physiology, University of Toyama, Japan, 2Department
of Synthetic and Medicinal Chemistry, University of Toyama, Japan

Epithelial Transport, Secretion & Absorption: Epithelium (2)2P-381

ZO family proteins regulate epithelial polarity independent of Tight
Junction strand assembly
Tetsuhisa Otani1,2), Shinsaku Tokuda3), Mikio Furuse1,2)

Division of Cell Structure, National Institute for Physiological Sciences, Japan,
Department of Physiological Sciences, School of Life Sciences, The Graduate School
for Advanced Studies (SOKENDAI), Japan, 3Division of Nephrology and Hypertension,
Department of Internal Medicine, University of Kansas Medical Center, USA
1
2

2P-382

Establishment of a tight junction-deficient epithelial cell line bygenome editing of claudin genes
Mikio Furuse1), Tetsuhisa Otani1), Daichi Sugawara1), Shinsaku Tokuda2),
Mika Watanabe1), Kyoko Furuse1), Osamu Nagata1)

Epithelial Transport, Secretion & Absorption: G-I tract (2)2P-383

Electrogenic K+ secretion induced by butyrate in rat rectal colon
Akihiro Inagaki1), Mikio Hayashi2), Naaz Andharia2), Hiroko Matsuda2)

Institute of Biomedical Sciences, Tokushima University Graduate School, Japan,
Department of Physiology, Kansai Medical University, Japan1
2

2P-384

Dragon fruit oligosaccharide ingestion enhances mouse intestinal
motility
Pissared Khuituan1), Sakena K-Da1,2), Kanrawee Bannob1,2),
Fittree Hayeeawaema1), Santad Wichienchot3), Saranya Peerakietkhajorn2),
Narattaphol Charoenphandhu4)

Department of Physiology, Faculty of Science, Prince of Songkla University, Thailand,
Department of Biology, Faculty of Science, Prince of Songkla University, Thailand,Interdisciplinary Graduate School of Nutraceutical and Functional Food, Prince ofSongkla University, Thailand, 4Department of Physiology, Faculty of Science, Mahidol
University, Thailand
12
3

2P-386The Effect of Fermented Milk and Soy for Controling Blood Glucose
and Lipid Level on Rats
Lovita Adriani1), Ronny Lesmana2)

1
Animal Husbandry Faculty, Padjadjaran University, Indonesia, 2Departement of Basic
Science, Faculty of Medicine, Padjadjaran University, Indonesia

2P-387

Effects of dragon fruit oligosaccharide on microbiota in proximal anddistal colon of mouse
Saranya Peerakietkhajorn1), Nilobon Jeanmard1), Papatsorn Chuenpanitkit1),
Sakena K-Da1,2), Kanrawee Bannop1), Pissared Khuituan2)

Department of Biology, Faculty of Science, Prince of Songkla University, Thailand,
Department of Physiology, Faculty of Science, Prince of Songkla University, Thailand

12

2P-388

Daikenchuto ameliorates intestinal fibrosis by activating myo­
fibroblast TRPA1 channel
Keizo Hiraishi1), Lin-Hai Kurahara1), Yaopeng Hu1), Kaori Koga2),
Miki Onitsuka2), Ryuji Inoue1)

1
Department of Physiology, School of Medicine, Fukuoka university, Japan, 2Departmentof Pathology, School of Medicine, Fukuoka university, Japan

2P-389The peripheral regulation of rectal visceral sensation by 5-HT4-cAMP
and NO-cGMP pathways

Epithelial Transport, Secretion & Absorption: Epithelium (2)/Epithelial Transport, Secretion & Absorption: G-I tract (2)

DAY 3

1
Division of Cell Structure, National Institute for Physiological Sciences, Japan, 2Kidney
Institute, KUMC School of Medicine, USA

Kazumasa Matsumoto-Miyai1), Junichi Hashimoto1),
Eriko Okuyama-Shinzawa2), Masahito Kawatani2)
Graduate School of Comprehensive Rehabilitation, Osaka Prefecture University, Japan,
Department of Neurophysiology, Akita University Graduate School of Medicine, Japan1
2

2P-390

Calcium Oscillation Complexes in Colonic Musculatures of Mice
Shinsuke Nakayama1), Chiho Takai1), Takana Yamada1), Naoko Iwata1),
Kazunori Kanemaru2,3), Kenji Tanaka4), Masamitsu Iino2,3)Department of Cell Physiology, Nagoya University Graduate School of Medicine,
Department of Pharmacology, Graduate School of Medicine, The University of Tokyo,
Division of Cellular and Molecular Pharmacology, Nihon University School of Medicine,
4
Department of Neuropsychiatry, Keio University School of Medicine
1
2
3

2P-391Chronic vomiting observed in captive common marmosets
Yumiko Yamazaki1), Shinpei Kawarai2), Hidetoshi Morita3),
Takefumi Kikusui4), Atsushi Iriki1)

Laboratory for Symbolic Cognitive Development, RIKEN Center for Biosystems
Dynamics Research, 2Laboratory of Small Animal Clinics, Veterinary Teaching Hospital,
Azabu University, 3Graduate School of Environmental and Life Science, Okayama
University, 4Companion Animal Research, School of Veterinary Medicine, Azabu
University
1

2P-392

Clostridium difficile disrupts epithelial barrier function by altering tightjunction proteins
Pei-Jane Tsai, Tai-Chieh Wu, Yi-Hsin Lai

Department of Medical Laboratory Science and Biotechnology, University of National
Cheng-Kung University

2P-393Characterization of physiological function of IBD-associated gene
LRRK2 in mouse intestine
Yuta Ishikawa, Fumitaka Kawakami, Rei Kawashima, Tatsunori Maekawa,
Fumitaka Ichikawa

Department of regulation Biochemistry, Graduate School of Medical Sciences, Kitasato
University

2P-394

Analysis of the effect of high-fat diet on intestinal barrier using mousecolitis model
Mayuka Yamashita, Fumitaka Kawakami, Rei Kawashima,
Tatsunori Maekawa, Fumitaka Ichikawa

Department of Regulation Biochemistry, Graduate School of Medical Sciences, Kitasato
University

Epithelial Transport, Secretion & Absorption: Renal Physiology (2)★ 2P-395(Y-28)

Protective effects of dapagliflozin and atorvastatin on renal function
in insulin-resistant rats
Laongdao Thongnak, Myat Theingi Swe, Krit Jaikumkao,
Anchalee Pongchaidecha, Anusorn Lungkaphin
Epithelial Transport and Intracellular Signaling Regulation Unit, Department of
Physiology, Chiang Mai University, Thailand

2P-396

Protective Effects of Agomelatine on Inflammation in Obesity-Induced
Kidney Injury
Sasivimon Promsan, Rada Chenwelling, Anchalee Pongchaidecha,
Anusorn Lungkaphin

Epithelial Transport and Intracellular Signaling Regulation Unit, Chiang Mai University,
ThailandEpithelial Transport, Secretion & Absorption: G-I tract (2)/Epithelial Transport, Secretion & Absorption: Renal Physiology (2)★ 2P-397(Y-29)

Melatonin activates sirtuin 3 to protect the kidney from long-term
consequences of bisphenol A
Anongporn Kobroob1), Wachirasek Peerapanyasut2), Sirinart Kumfu3),
Nipon Chattipakorn3), Orawan Wongmekiat2)
Division of Physiology, School of Medical Sciences, University of Phayao, Thailand,
Renal Physiology Unit, Department of Physiology, Faculty of Medicine, Chiang Mai
University, Thailand, 3Cardiac Electrophysiology Research and Training Center,
Department of Physiology, Faculty of Medicine, Chiang Mai University, Thailand
12

2P-398

Effects of chronic renal failure on cognitive function and neurogenesis
in rats
Rina Murata Murata, Masanori Katakura, Haruka Matsuzawa

The application of predictive equation on estimation sodium intake in
Hong Kong young adults
Ka Tik Cheung, Samuel Sze Ming Wong

School of Medical and Health Sciences, Tung Wha College, Hong Kong

Molecular & Cellular Biology: Channels & Transporters (2)2P-400Withdrawn

2P-401

Inhibitory effect of a novel less-odorous TRPA1 antagonist

Masayuki Takaishi1), Yutaro Koide1), Maki Sawada1), Yoshiro Suzuki2,3),
Fumitaka Fujita1), Makoto Tominaga2,3)1
Mandom Corp., Japan, 2National Institute for Physiological Sciences (Exploratory
Research Center on Life and Living Systems), National Institutes of Natural Sciences,
Japan, 3Department of Physiological Sciences, SOKENDAI, (The Graduate University for
Advanced Studies), Japan

2P-402

Regulation of the leak channel NALCN by H2O2
Hyunsu Kang1), Jong-Sun Kang2), Hana Cho1)

Department of Physiology, Single Cell Network Research Center, Sungkyunkwan
University School of Medicine, South Korea, 2Department of Molecular Cell Biology,
Single Cell Network Research Center, Sungkyunkwan University School of Medicine,South Korea
12P-403

Regulation of reactive oxygen species and calcium by chloride
intracellular channel 1 in A549 cells
Jongyoon Lee1), Jaerin Lee2), Myongjoon Hahn2), Jongsun Kang2),
Hana Cho1)

Department of Physiology, University of Sungkyunkwan, School of Medicine, South
Korea, 2Department of Molecular Cell Biology, Single Cell Network Research Center,
University of Sungkyunkwan, School of Medicine, South Korea
12P-404

Ferulic acid enhanced L-type Ca2+ channel function in rat insulinoma
cell line
Katesirin Ruamyod, Wattana B Watanapa, Pimchanok Nambandit ,Sukrit Treewaree, Parin Wongsanupa

Department of Physiology, Faculty of Medicine Siriraj Hospital, Mahidol University,
Thailand

2P-405High Glucose-Induced Alterations in Ion Channel and VascularFunctions in Human Umbilical Vein

Epithelial Transport, Secretion & Absorption: Renal Physiology (2)/Molecular & Cellular Biology: Channels & Transporters (2)DAY 3

Department of Pharmaceutical Sciences, University of Josai, Japan

2P-399Aung Hein Nyan1,2), Wattana B Watanapa2), Suwattanee Kooptiwut2),
Pinpat Tripatara3)
Defence Services Medical Research Center, Myanmar, 2Department of Physiology,
Faculty of Medicine Siriraj Hospital, Mahidol University, Thailand, 3Department ofPharmacology, Faculty of Medicine Siriraj Hospital, Mahidol University, Thailand
1

2P-406

Mechanism of ginsenoside Re effect on SKCa current in humancoronary artery endothelial cell
Kitinat Rodthongdee, Luecha Boontaveekul, Wattana B Watanapa

Department of Physiology, Faculty of Medicine Siriraj Hospital, Mahidol University,
Thailand

2P-407

Gq-mediated activation of non-selective cation channels in insulin
releasing b-cells
Dezaki Katsuya1), Masashi Yoshida2), Toshihiko Yada1)

1Department of Physiology, Jichi Medical University, Japan, 2Saitama Medical Center,
Jichi Medical University, Japan

2P-408

Polyamine-mediated inward rectification of TRPC4 channel
Jinsung Kim, Insuk So

Department of Physiology, Seoul National University, Korea

2P-409Effect of STIM1 knockdown on calcium response in bovine ciliary
myocytesMiyazu Motoi, Kosuke Takeya, Toshiyuki Kaneko, Akira Takai
Dept Physiol, Asahikawa Med, Univ., Japan

2P-410

TRPM4 channel is involved in cellular damage caused by simulated
ischemia-reperfusion injury
Chen Wang, Heng Wei

Department of Cardiovascular Physiology,University of Okayama,Japan

2P-411

Molecular property changes of endoplasmic reticulum IKCa channels
in early diabetic hepatocytes
Maedeh Ghasemi1), Afsaneh Eliassi 2,3)

Department of Physiology, School of Medicine, Isfahan University of Medical Sciences,Iran, 2Department of Physiology, School of Medicine, Shahid Beheshti University of
Medical Sciences, Iran, 3Neurosphysiology research centre, School of Medicine, Shahid
Beheshti University of Medical Sciences, Iran1

2P-412

TRPM2 channel-Stat3 complex regulates the polarity of tumorassociated macrophage
Yuji Yamada, Yoshifumi Ueda, Ryuhei Kurogi, Yoshiaki Hasegawa,Tarek Mohamed Abd El-Aziz, Masayuki x Mori, Yasuo Mori

Department of Synthetic Chemistry and Biological Chemistry, Graduate School ofEngineering, Kyoto University, Japan

2P-413

Regulation of neuronal excitability by Trim69 E3 ubiquitin ligase
Chankyo Kim1), Seul-Yi Lee1), Hyeon-Ju Jeong2), Hyun-Kyung So2),
Yoo-Bin Kim1), Jae-Rin Lee2), Myong-Joon Hahn2), Jong-Sun Kang2),
Hana Cho1)

Department of Physiology, Single Cell Network Resarch Center, Sungkyunkwan
University School of Medicine, Korea, 2Department of Molecular Cell Biology, Single Cell
Network Resarch Center, Sungkyunkwan University School of Medicine, Korea
12P-414

Activation of TRPM6 current by 2-aminoethyldiphenyl borate isimpaired by hydrogen peroxide
Ryo Mizumoto1), Dai Masui2), Hana Inoue1), Masato Konishi1)

Molecular & Cellular Biology: Channels & Transporters (2)1
Department of Physiology, Tokyo Medical University, Japan, 2Department of Chemistry,
Tokyo Medical University, Japan

2P-415Structure-based virtual screening for G protein-gated inwardly
rectifying K+ (GIRK) channel blockers
Atsushi Inanobe, Yoshihisa Kurachi

Department of Pharmacology, Osaka University Graduate School of Medicine, Japan

2P-416

A novel variant of TRPV3 p.A628T in East Asians showing fastsensitization by chemical agonists
Choi Si Won1,3), Seong Woo Choi7,8), Jeesoo Chae2,5,6), Jong-Il Kim2,5,6),
Sung Joon Kim1,3,4)

2P-417Structure analysis of the binding between Cav1.2 channel andcalmodulin
Masaki Kameyama, Etsuko Minobe, Jianjun Xu, Qinghua Gao
Kagoshima University, Japan

2P-418Voltage-clamp fluorometry analyses of voltage-dependent gating of
ATP receptor channel P2X2
Andriani Tsari Rizki1,2), Yoshihiro Kubo1,2)

1
Div Biophys and Neurobiol, Natl Inst Physiol Sci, Japan, 2Dept Physiol Sci, SOKENDAI,
Japan

2P-419Functional Coupling of Metabolic Sensors, TRPM2 and Sirtuin
Makiko Kashio1), Makoto Tominaga2,3,4), Satoru Masubuchi1)
12P-420Aichi Med Univ, Japan, 2ExCELLS, NIPS, 3SOKENDAI, 4Juntendo Univ

Examination of the contribution of SLCO2A1 to maxi-anion channel
currents in murine cells
Toshiaki Okada1), Yasunobu Okada1,2)

1
Division of Cell Signaling, National Institute for Physiological Sciences, Japan, 2Dept.
Physiol., Kyoto Pref. Univ. Med., Japan★★2P-421(Y-30)

Protein arginine methyltransferase 1-dependent regulation of slow
delayed rectifier K+ current
Hyun-Ji Kim1,3), Bok-Geon Kim2,3), Chang-Seok Ki4), Jong-Sun Kang2,3),
Hana Cho1,3)

1Department of Physiology, University of Sungkyunkwan, Korea, 2Department of
Molecular and Cellular Biology, Sungkyunkwan University School of Medicin, Republicof Korea, 3Single Cell Network Research Center, Sungkyunkwan University School of
Medicine, Republic of Korea, 4Department of Laboratory Medicine and Genetics,
Samsung Medical Center, Sunkyunkwan University School of Medicine, Republic of
Korea

2P-422

Effects of chemical chaperone on surface expression of PHHI mutant
KATP channel (SUR1/A28VKir6.2)
Chen Pei-Chun1,2), Yu-Chi Lin1), Yen-Yu Yang3), Shi-Bing Yang3)

1
Department of Physiology, National Cheng Kung University, Taiwan, 2Graduate
Institute of Basic Medicine, 3Institute of Biomedical Sciences, Academia Sinica, Taiwan

Molecular & Cellular Biology: Channels & Transporters (2)

DAY 3

1
Department of Physiology Seoul National University College of Medicine, 2Departmentof Biochemistry and Molecular Biology Seoul National University College of Medicine,3
Department of Biomedical Sciences Seoul National University College of Medicine,
4Ischemic/Hypoxic Disease Institute Seoul National University College of Medicine,
5
Genomic Medicine Institute Seoul National University College of Medicine, 6Cancer
Research Institute Seoul National University College of Medicine, 7Department of Stem
Cell Biology Konkuk University School of Medicine, 8Konkuk University School of
Medicine, Republic of Korea

2P-423

Effects of antihistamine drugs on G-protein-gated inwardly rectifying
K+ channels
Chang Liu1,2), I-Shan Chen1,2), Yoshihiro Kubo1,2)

Division Biophysics and Neurobiology, Department of Molecular and Cellular
Physiology, National Institute for Physiological Sciences, Japan, 2Department of
Physiological Sciences, School of Life Science, SOKENDAI, Japan1

2P-424

Measurements of water flux across a lipid bilayer membrane withevaluation of unstirred water layer
Keita Yano, Masayuki Iwamoto, Shigetoshi Oiki

Department of Molecular Physiology & Biophysics, University of Fukui Faculty of
Medical Sciences, Japan

2P-425in bulla channel synthesis and functional expression system underapplied membrane potentials
Masayuki Iwamoto, Shigetoshi Oiki

Department of Molecular Physiology and Biophysics, University of Fukui, Japan

2P-426

Regulation of TRPV1 and TRPA1 function by free fatty acid receptor
Pyo Hyun-Jeong1), Myong-Ho Jeong2), Tong Mook Kang1), Jong-Sun Kang2),
Hana Cho1)

Department of Physiology, Single Cell Network Research Center, Sungkyunkwan
University School of Medicine, Korea, 2Department of Molecular Cell Biology, Single Cell
Network Research Center, Sungkyunkwan University School of Medicine, Korea
12P-427

Cav1.2 channel inactivation induced by two molecules of calmodulin
Etsuko Minobe1), Masayuki X Mori2), Masaki Kameyama1)

1Department of Physiology, Kagoshima University, Japan, 2Laboratoty of Molecular
Biology, Department of Synthetic Chemistry and Biological Chemistry, Kyoto University,Japan

2P-428

Dipole Potential Evaluated by Hydrophobic Ions using the Contact
Bubble Bilayer Method
Yuka Matsuki1,2), Masayuki Iwamoto2), Mariko Yamatake2), Shigetoshi Oiki2)

Department of Anesthesiology & Reanimatology, University of Fukui, Faculty of
Medicine Sciences, Japan, 2Departments of Molecular Physiology and Biophysics,
Faculty of Medicine Sciences, The University of Fukui, Japan

1★★2P-429(Y-31)TTYH family encodes the pore-forming subunits of the volume-regulated anion channel in the brain
Han Youne-Eun1,2,3), Jea Kwon1,2,4), Joungha Won1,2,5), Heeyoung An1,2,4),
Minwoo Wendy Jang1,2,4), Junsung Woo1,2), Je Sun Lee6), Min Gu Park1,2,4),
Soo-Jin Oh1,2,7), Changjoon Justin Lee1,2,3),

Center for Neural Science and Functional Connectomics, Korea Institute of Scienceand Technology (KIST), Korea, 2Center for Glia-Neuron Interaction, Korea Institute of
Science and Technology (KIST), Republic of Korea, 3Department of Neuroscience,
Division of Bio-Medical Science & Technology, KIST School, Korea University of Scienceand Technology, Republic of Korea, 4KU-KIST, Graduate School of Converging Scienceand Technology, Korea University, Republic of Korea, 5Department of Biological
Sciences, Korea Advanced Institute of Science and Technology (KAIST), Republic ofKorea, 6Molecular Neurobiology Laboratory, Dept. of Structure and Function of Neural
Network, Korea Brain Research Institute, Republic of Korea, 7Convergence ResearchCenter for Diagnosis, Treatment and Care System of Dementia, Korea Institute of
Science and Technology (KIST), Republic of Korea
1

Molecular & Cellular Biology: Channels & Transporters (2)★ 2P-430(Y-32)The Arginine in the side portal determines the physiological [pH]osensing of TALK1
Tsai Wen-Hao1,2), Shi-Bing Yang1)
1
Institute of Biomedical Science, Academia Sinica, Taiwan , 2 Taiwan International
Graduate Program-Molecular Medicine, National Yang-Ming University Taiwan

2P-431

Down-regulation of KCa3.1 K+ channels by the treatment with VDRagonists in mouse pre-osteoblasts
Hiroaki Kito1), Haruka Morihiro2), Susumu Ohya1)

Department of Pharmacology, Graduate School of Medical Sciences, Nagoya City
University, Japan, 2Department of Pharmacology, Division of Phathological Sciences,
Kyoto Pharmaceutical University
1

2P-432Cell imaging with magnetic particle with on a diamond sensor
Yoshie Harada1), Takeharu Sekiguchi1,2), Takayuki Iwasaki3),
Mutsuko Hatano3), Yuji Hatano1)

1
Institute for Protein Research, Osaka University, Japan, 2Graduate School of Scienceand Technology, Keio University, 3School of Engineering, Tokyo Institute of Technology

2P-433

A novel mechanism responsible for the intracellular zinc-sensing
Zhelong Xu, Huanhuan Zhao, Liang Zhao

Department of Physiology and Pathophysiology, Tianjin Medical University, China

2P-434

TRPA1 receptors mediate the hypoxia-induced surfacing response ofgoldfish
Masanori Kasai, Aika Kawabata, Rina Nakashima, Takuya Iwao,
Yuya Horinouchi, Mitsuhiro Kimura, Yukiko Yokogawa

Chemistry and BioScience Course, Research Field in Science, Science and Engineering
Area,Research and Education Assembly, Kagoshima University, Japan

2P-435MicroRNAs in mouse salivary glands as a putative Bio-Marker ofstress-dependent diseases
Kinji Kurihara

Department of Physiology, Meikai University, School of Dentistry, Japan★★2P-436(Y-33)

Circadian gene Clock post-transcriptionally regulates mitochondrial
morphology and functions
Lirong Xu1), Qianyun Cheng1), Bingxuan Hua3), Tingting Cai1), Jiaxin Lin1),
Gongsheng Yuan1), Zuoqin Yan3), Xiaobo Li1), Ning Sun1), Chao Lu1,2),
Ruizhe Qian1,2)

Department of Physiology and Pathophysiology, School of Basic Medical Sciences,
Fudan University, China , 2Basic Research Institute for Aging and Medicine, School of
Basic Medical Sciences, Fudan University, China, 3Department of Orthopedics,
Zhongshan Hospital, Fudan University,China
1

2P-437

Improvement of genetically encoded probe to measure Ca2+ dynamics
in subcellular compartments
Naoya Murooka, Takashi Kikuchi, Hideki Shirakawa

Department of Engineering Science, The University of Electro-Communications, Japan

2P-438

Method to Record Single-Molecule Fluctuations and Conformational
Changes in Proteins
Hirofumi Shimizu1), Masayuki Iwamoto1), Kentaro Kajiwara2),

Molecular & Cellular Biology: Channels & Transporters (2)/Molecular & Cellular Biology: Cellular Physiology (2)DAY 3

Molecular & Cellular Biology: Cellular Physiology (2)Yoshikazu Hirai3), Osamu Tabata3)
12

2P-439Department of Molecular Physiology and Biophysics, University of Fukui, Japan,
SPring-8/JASRI, 3Department of Micro Engineering, Kyoto University

Development of a photo-activatable CaMKII and its application to thestudy of synaptic plasticity
Akihiro Shibata, Hideji Murakoshi

National Institute for Physiological Sciences , Japan

2P-440

Truncated dystrophin ameliorates the dystrophic phenotype bysarcolipin-mediated SERCA inhibition
Jun Tanihata1,2), Tetsuya Nagata2), Naoki Ito2), Takashi Saito2),
Akinori Nakamura3), Susumu Minamisawa1), Yoshitsugu Aoki2), Urs Ruegg4),
Shin’Ichi Takeda2)

Department of Cell Physiology, The Jikei University School of Medicine, Japan,
Department of Molecular Therapy, National Institute of Neuroscience, National Centerof Neurology and Psychiatry (NCNP), Japan, 3Third Department of Internal Medicine,
Shinshu University School of Medicine, Japan., 4Pharmacology, Geneva-Lausanne
School of Pharmaceutical Sciences, University of Geneva, Switzerland
1
2

2P-441

Flonicamid affects insect proprioception and feeding through 5-HT7
receptors
Fen Mao, Yixiang Qi, Gongyin Ye, Jia Huang

Institute of insect science, University of Zhejiang, China

2P-442Analysis of electrically-modulated molecules that enhance bonemarrow stromal cell proliferation
Jun Ichikawa, Ryuji Inoue

Department of Physiology, Fukuoka University School of Medicine, Japan

2P-443Involvement of VNUT-exocytosis in TRPV4 ion channel-dependent
ATP release from colonic epithelium
Hiroshi Mihara1,2), Kunitoshi Uchida3), Schuichi Koizumi4),
Yoshinori Moriyama5)Center for Medical Education and Career Development, University of Toyama, Japan,
Department of Gastroenterology, University of Toyama, Japan, 3Department of
Physiological Science and Molecular Biology, Fukuoka Dental College, Japan ,4
Department of Neuropharmacology, University of Yamanashi, Japan, 5Department of
Membrane Biochemistry, Graduate School of Medicine, Dentistry and Pharmaceutical
Sciences, Okayama University, Japan1
2

2P-444

Essential role of Ca2+ and pH for in vitro cornification in isolatedmouse stratum granulosum cells
Takeshi Matsui1), Masayuki Amagai1,2)
1
2

2P-445

Laboratory for Skin Homeostasis, RIKEN Center for Integrative Medical Sciences, Japan,
Department of Dermatology, Keio University School of Medicine

CTLA4-Ig suppressed intracellular calcium oscillation and inhibitedmurine osteoclast formation
Hiroyuki Okada1), Hiroshi Kajiya2), Yasunori Omata1), Jun Hirose1),
Takumi Matsumoto1), Koji Okabe2), Takeshi Miyamoto3), Sakae Tanaka1)

1
Department of Orthopaedic Surgery, the University of Tokyo, Japan, 2Department of
Physiological Science and Molecular Biology, Fukuoka Dental College, 3Department ofOrthopaedic Surgery, Keio University School of Medicine

2P-446

Metabotropic glutamate receptor mGlu2 regulates signaling via Gqcoupled serotonergic receptor
Molecular & Cellular Biology: Cellular Physiology (2)Michihiro Tateyama1,2), Yoshihiro Kubo1,2)
Division of Biophysics and Neurobiology, Department of Molecular and Cellular
Physiology, National Institute for Physiological Sciences, Japan, 2Department of
Physiological Sciences, SOKENDAI, Japan1

2P-447

Altered expression of taste signaling elements in jejunal tissue ofobese patients
Toshiaki Yasuo1,2), Peihua Jiang2), Craig Wood3), Xin Chu3), Peter Benotti3),
Christopher Still3), David DK Rolston3), Robert F Margolskee2),
Yuzo Ninomiya2,4)

1
Department of Oral Physiology, Asahi University School of Dentistry, Japan, 2Monell
Chemical Senses Center, USA, 3Geisinger Medical Center, USA, 4Research andDevelopment Center for Taste and Odor Sensing, Kyushu University, Japan

The intracellular C-terminal domain is responsible for cell surface
expression of mGluR6
Dilip Rai, Takumi Akagi, Atsushi Shimohata, Ikuo Ogiwara, Makoto Kaneda
Department of Physiology I, Nippon Medical School, Japan

2P-449Effects of PCSK9 inhibitor and atorvastatin on mitochondria of red
muscle fibers in obesity
Chanisa Thonusin1,2,3), Siripong Palee1,2), Wasana Pratchayasakul1,2,3),
Patchareeya Amput1,2), Sasiwan Kerdpoo1,2), Thidarat Jaiwongkam1,2),
Nattayaporn Apaijai1,2), Siriporn C Chattipakorn1,2,4), Nipon Chattipakorn1,2,3)

Cardiac Electrophysiology Research and Training Center, Chiang Mai University,
Thailand, 2Center of Excellence in Cardiac Electrophysiology Research, Chiang Mai
University, Thailand, 3Department of Physiology, Faculty of Medicine, Chiang Mai
University, Thailand, 4Department of Oral Biology and Diagnostic Sciences, Faculty of
Dentistry, Chiang Mai University, Thailand
1

2P-450Intracellular calcium responses to mechanical stimulation in mouseand human synoviocytes
Keiji Asada1,2), Yu Okumura2,3), Miyako Takaki2)

Department of Physical Therapy, Faculty of Medical Science, Suzuka University of
Medical Science, Japan, 2Department of Orthopaedic Surgery, Nara Medical
University, Japan, 3Department of Physical Therapy, Faculty of Human Science, Osaka
University of Human Science, Japan1

2P-451

Global analysis of specific gene expression in thymus gland of AQP11null mice
Yasuko Tanaka, Yumi Tsuji, Natsumi Kato, Minori Nakae, Haruka Okada,Kei Masaka, Kenichi Ishibashi
Department of Medical Physiology, Japan

2P-452Different expression of Olig2 and O4 in cultured mouse brain cells
Hiromi Hiruma

Department of Physiology, Kitasato University School of Medicine, Japan

2P-453

L6H21 reduces EtOH-LPS-induced liver injury through inhibition of
NLRP3 inflammasome activation
Kong Xiaoxia1), Guicheng Wu2,4), Fengyuan Li4), Hongyu Zhang3),
Wenke Feng4)

1
Institute of Hypoxia Research, Wenzhou Medical University, China, 2Department of
Hepatology, Three Gorges Central Hospita, China, 3School of Pharmaceutical Sciences,Wenzhou Medical University, China, 4Departments of Pharmacology & Toxicology andMedicine, Alcohol Research Center, Hepatobiology & Toxicology Program, University ofLouisville, USA

Molecular & Cellular Biology: Cellular Physiology (2)DAY 3

2P-448

2P-454

MitoQ protects endothelial barrier injury and inflammation by inhibiting
ROS and autophagy in HUVECs
Chen Sha1), Yu Wang1), Hailin Zhang2), Ran Chen1), Li Yang3)

School of Basic Medical Sciences, Institute of Hypoxia Research, Wenzhou Medical
University, China, 2Department of Children’s Respiration, The Second Affiliated Hospital& Yuying Children's Hospital, Wenzhou Medical University, China, 3Department ofRespiratory Medicine, The First Affiliated Hospital of Wenzhou Medical University, China
12P-455

MR-1 promotes cardiomyogenic differnentiation of H9c2 cells via the
myogenin-mediated pathway
Wang Xiaoreng, Dandan Song, Tianqi Tao, Xiuhua Liu
Department of Pathophysiology,301 hospital, China

2P-456

Nardilysin in hepatocyte regulates adaptive thermogenesis in brown
adipose tissue
Eiichiro Nishi1), Hirotaka Iwasaki1), Kiyoto Nishi3), Mikiko Ohno1),
Shintaro Matsuda2)

1
Department of Pharmacology, Shiga University of Medical Science, Japan, 2Departmentof Cardiovascular Medicine, Graduate School of Medicine, Kyoto University,
3
Department of Anesthesiology & Pain Medicine University of Washington

2P-457Structure Development of Oxolinic Acid, a Novel Inhibitor of Type 1
Ryanodine Receptor
Yoshiaki Nishijima1), Takashi Murayama1), Shuichi Mori2), Hiroto Iinuma2),
Noriaki Manaka2), Nagomi Kurebayashi1), Mari Ishigami-Yuasa2),
Hiroyuki Kagechika2), Takashi Sakurai1)

Department of Pharmacology, Juntendo University School of Medicine, Japan,
Institute of Biomaterials and Bioengineering, Tokyo Medical and Dental University,
Japan

1
2

2P-458

Ribosome binding protein GCN1L1 controls cell cycle and is essential
for embryonic development
Hiromi Yamazaki, Shuya Kasai, Junsei Mimura, Peng Ye,
Atsushi Inose Maruyama, Ken Itoh

Department of Stress Response Science, Hirosaki University Graduate School of
Medicine, Japan

2P-459Malignancy of cancer cell lines correlates with NKCC1 expression
and intracellular Cl- concentration
Hiroaki Miyazaki

Department of Life Science, Setsunan University, Japan

2P-460

Structure of bound water in myofibril suspension: A role of ATP
Tetsuo Ohno

Department Molecular Physiology, The Jikei University School of Medicine, Japan

2P-461mTORC2 signaling is critical for lysosomal activation by isorhamnetin
treatment in J774.1
Maiko Sakai1), Kohta Ohnishi1), Teppei Fukuda1), Masashi Masuda1),
Naomi Abe-Kanoh2), Hisami Yamanaka-Okumura1), Yoshichika Kawai3),
Yutaka Taketani1)

Department of Clinical Food Management, Graduate School of Biomedical Sciences,
Tokushima University, Japan, 2Department of Public Health and Applied Nutrition,
Graduate School of Biomedical Sciences, Tokushima University, Japan, 3Department ofFood Science, Graduate School of Biomedical Sciences, Tokushima University, Japan1

Molecular & Cellular Biology: Cellular Physiology (2)2P-462

Novel RyR1 Inhibitors Identified by High-Throughput Screening
Using ER Ca2+ Measurement
Hiroyuki Matsukawa1), Takashi Murayama1), Takuya Kobayashi1),
Nagomi Kurebayashi1), Mari Ishigami-Yuasa2), Shuichi Mori2),
Hiroyuki Kagechika2), Takashi Sakurai1)

Department of Pharmacology, Juntendo University School of Medicine, Japan,
Institute of Biomaterials and Bioengineering, Tokyo Medical and Dental University,
Japan

1
2

2P-463

Regulation of cell cycle by N6-methyladenosine modification in cancer
cells
Department of Molecular Physiology, Faculty of Life Sciences, Kumamoto University,
Japan, 2Department of Oral and Maxillofacial Surgery, Faculty of Life Sciences,
Kumamoto University, Japan1

2P-465

Inhibition of the frequency of airway ciliary beating by PDE1 activationin Down syndrome mouse
Haruka Kogiso1,2), Yukiko Ikeuchi1,2), Saori Tanaka3), Shigekuni Hosogi1),
Chikao Shimamoto3), Matthieu Raveau4), Kazuhiro Yamakawa4),
Takashi Nakahari5), Shinji Asano2), Yoshinori Marunaka1,5,6),

Department of Molecular Cell Physiology, Graduate School of Medical Science, Kyoto
Prefectural University of Medicine, Japan, 2Department of Molecular Physiology,
College of Pharmaceutical Sciences, Ritsumeikan University, Japan, 3Laboratory of
Pharmacotherapy, Osaka University of Pharmaceutical Sciences, Japan, 4Laboratory for
Neurogenetics, RIKEN, Brain Science Institute, Japan, 5Research Center for Drug
Discovery and Pharmaceutical Development Science, Research Organization of
Science and Technology, BKC, Ritsumeikan University, Japan, 6Research Institute forClinical Physiology, Kyoto Industrial Health Association, Japan1

2P-466Microscale liquid layer on the olfacrory receptors affects on the vapor
chemical detection
Koji Sato

Biofunctional Systems Construction Research Group, Exploratory Research Center onLife and Living Systems, Japan

2P-467

Differential effects of Fe2+ and Fe3+ on the proliferation and differentiation of osteoblasts
Ketsaraporn Nammultriputtar1,2), Kornkamon - Lertsuwan1,3),
Narattaphol Charoenphandhu1,2,4,5)Center of Calcium and Bone Research (COCAB), Faculty of Science, Mahidol University,
Thailand, 2Department of Physiology, Faculty of Science, Mahidol University, Thailand,
3
Department of Biochemistry, Faculty of Science, Mahidol University, Thailand, 4Instituteof Molecular Biosciences, Mahidol University, Thailand, 5The Academy of Science, The
Royal Society of Thailand, Thailand
1

2P-468

Synergistic effect of histone deacetylase inhibitors in intravesicalinstillation of bladder cancer
Wen-Wei Sung1,2,3), Chia-Ying Yu2), Jr-Rou Sun2), Shao-Chuan Wang1,2,3),
Wen-Jung Chen1,2,3), Tzuo-Yi Hsieh1,2,3), Sung-Lang Chen1,2,3)

1
Department of Urology, Chung Shan Medical University Hospital, Taiwan, 2School of
Medicine, Chung Shan Medical University, Taiwan, 3Institute of Medicine, Chung Shan
Medical University, Taiwan

Molecular & Cellular Biology: Cellular Physiology (2)DAY 3Mayumi Hirayama1,2), Fanyan Wei1), Hideki Nakayama2),
Kazuhito Tomizawa1)

2P-469

Neferine selectively alters LPS-induced inflammatory responses in
RAW 264.7 macrophages
Amnart Onsa-Ard1), Jiraporn Tocharus2), Chainarong Tocharus3),
Apichart Suksamrarn4)

Division of Biochemistry, Faculty of Medical Sciences, University of Phayao, Thailand.,
Department of Physiology, Faculty of Medicine, Chiang Mai University, Thailand,
Department of Anatomy, Faculty of Medicine, Chiang Mai University, Thailand.,
4
Department of Chemistry and Center of Excellence for Innovation in Chemistry,
Faculty of Science, Ramkhamhaeng University, Thailand
12
3

2P-470The influence of KATP channel abnormality on calcium handling ofendoplasmic reticulum
Hiroki Takanari

Tokushima University Hospital, Japan

2P-471

Dinaciclib inhibits Aurora A expression and proliferation of prostatecancer cells
Ho Lin1), Ting-Chieh Chang1), Chang-Tze Ricky Yu3), Chun-Chi Wu2),
Mei-Chih Chen4,5)1
Department of Life Sciences, National Chung Hsing University, Taiwan, 2Institute ofMedicine, Chung-Shan Medical University, Taiwan, 3Department of Applied Chemistry,
National Chi Nan University, Taiwan, 4Medical Research Center for Exosomes andMitochondria Related Diseases, China Medical University Hospital, Taiwan, 5Departmentof Nursing, Asia University, Taiwan

2P-472Dose-response relationship of free radical scavenging activity ofdexmedetomidine
Osamu Tokumaru1), Kota Yoshida2), Kazue Ogata3), Hiroki Takanari4),
Shigekiyo Matsumoto3), Takaaki Kitano3)

Faculty of Welfare and Health Sciences, Oita University, Japan, 2School of Medicine,
Oita University Faculty of Medicine, 3Department of Anesthesiology, Oita University
Faculty of Medicine, 4Clinical Research Center for Diabetes, Tokushima University
Hospital
1

2P-473

Airway ciliary beating activated by enhanced Ca2+ signal in Hochuekki-to (TJ-41) treated mice
Yukiko Ikeuchi1,2), Haruka Kogiso1,2), Saori Tanaka4), Shigekuni Hosogi1),
Takashi Nakahari3), Shinji Asano2), Yoshinori Marunaka1,3,5)

Department of Molecular Cell Physiology, Graduate School of Medical Science, Kyoto
Prefectural University of Medicine, Japan, 2Department of Molecular Physiology,
College of Pharmaceutical Sciences, Ritsumeikan University, Japan, 3Research Center
for Drug Discovery and Pharmaceutical Development Science, Research Organizationof Science and Technology, BKC, Ritsumeikan Universuty, Japan, 4Laboratory of
Pharmacotherapy, Osaka University of Pharmaceutical Sciences, Japan, 5ResearchInstitute for Clinical Physiology, Kyoto Industrial Health Association, Japan1

2P-474

Influence of TRPC knockout on mouse pupillary sphincter
Toshiyuki Kaneko, Akira Takai

Department of Physiology, Asahikawa Medical University, Japan

2P-475The inhibitory effects of microRNA-107 on p35/CDK5-regulated
prostate cancer cell growthFang-Ling Liu1), Wei-Hsiang Kao1), Hsin-Yi Wang2), Mei-Chih Chen3,4),
Ho Lin1)

Department of Life Sciences, National Chung Hsing University, Taiwan, 2Department of
Nuclear Medicine, Taichung Veterans General Hospital, Taiwan, 3Medical Research1

Molecular & Cellular Biology: Cellular Physiology (2)Center for Exosomes and Mitochondria Related Diseases, China Medical University
Hospital, Taiwan, 4Department of Nursing, Asia University, Taiwan

2P-476The inhibitory effects of valproic acid on androgen receptor andprostate cancer cell growth
Cheng-En Hsieh1), Hsiao-Han Kao1), Mei-Chih Chen2,3), Ching-Han Yu4),
Ho Lin1)

1
Department of Life Sciences, National Chung Hsing University, Taiwan, 2Medical
Research Center for Exosomes and Mitochondria Related Diseases, China Medical
University Hospital, Taiwan, 3Department of Nursing, Asia University, Taiwan,
4
Department of Medicine, Chung-Shan Medical University, Taiwan

2P-477

CDK5 promotes androgen receptor transactivation under Akt
inhibition stress
1
Department of Life Sciences, National Chung Hsing University, Taiwan, 2Medical
Research Center for Exosomes and Mitochondria Related Diseases, China Medical
University Hospital, Taiwan, 3Department of Nursing, Asia University, Taiwan

2P-478

CDK5 down-regulates p21 expression through inhibiting STAT3

Wan-Ling Liao1), Jo-Hsin Wang1), Pao-Hsuan Huang1), Hsin-Yi Wang2),
Mei-Chih Chen3,4), Ho Lin1)
Department of Life Sciences, National Chung Hsing University, Taiwan, 2Department of
Nuclear Medicine, Taichung Veterans General Hospital, Taiwan, 3Medical ResearchCenter for Exosomes and Mitochondria Related Diseases, China Medical University
Hospital, Taiwan, 4Department of Nursing, Asia University, Taiwan

1

2P-479Circadian rhythms in nicotinamide adenine dinucleotide con­centration in mouse liver
Aya Shimada, Hiroki Nakamura, Daisuke Yarimizu, Masao Doi
Department of Pharmaceutical Sciences, Kyoto University, Japan

2P-480Integrins are involved in mechano-electrical transduction in arterialbaroreceptors
Haixia Huang1), Haiyan Zhao2), Ping Liu1), Sitao Zhang1), Fang Xin1),
Wei Wang1)

Department of Physiology and Pathophysiology, School of Basic Medical Sciences,
Capital Medical University, China, 2Department of Functional Medicine, Yanjing Medical
College, Capital Medical University, China

1

2P-481

Vapor detection and discrimination with a panel of odorant receptors
Yosuke Fukutani1,2), Hitoshi Kida2,3), Joel D. Mainland4),
Claire A. De March2), Masaharu Kameda3), Masafumi Yohda1),
Hiroaki Matsunami2)

Department of Biotechnology and Life Science, Tokyo University of Agriculture andTechnology, Japan, 2Department of Molecular Genetics and Microbiology, Duke
University Medical Center, USA, 3Department of Mechanical System Engineering, Tokyo
University of Agriculture and Technology, Japan, 4Monell Chemical Senses Center, USA
12P-482

Metabolic alterations in cells transformed by oncogenic Lck kinase
Chao-Lan Yu1,2,3,4), Szu-Yuan Chen2), Mei-Ling Cheng1,2,3), Pei-Ting Wu2,3),
Fu-Shin Chueh5), Shin-Yu Wu1), Fu-Yu Chueh1,6)1
Department of Biomedical Sciences, Chang Gung University, Taiwan, 2Graduate
Institute of Biomedical Sciences, Chang Gung University, Taiwan, 3Healthy Aging
Research Center, Chang Gung University, Taiwan, 4Division of Hematology, Chang
Gung Memorial Hospital, Taiwan, 5Department of Food Nutrition and Health
Biotechnology, Asia University, Taiwan, 6Department of Pharmacy, Asia University
Hospital, Taiwan

Molecular & Cellular Biology: Cellular Physiology (2)DAY 3Wei-Hsiang Kao1), Mei-Chih Chen2,3), Ho Lin1)

2P-483

Effects of chloride ion channel blocker on the adipogenic differ­entiation of rabbit ASCs
Kanae Ouchi1,2), Masao Miyake1), Susumu Yoshie1), Akihiro Hazama1)
1
2

2P-484

Dept. Cellular and Integrative of Physiol., Fukushima Med. Univ. Grad. Sch. Med., Japan,
Dept. Judo Therapy, Koriyama Inst. Health Sci., Japan

ITAM receptors regulate two frequency components in calcium
oscillations during osteoclastogenesis
Hiroshi Kajiya1), Hiroyuki Okada2), Shunichi Sudo1), Masashi Shin1),
Fujio Okamoto1), Takeshi Miyamoto3), Sakae Tanaka2), Koji Okabe1)

Department of Physiological Science and Molecular Biology, Fukuoka Dental College,
Japan, 2Department of Orthopaedic Surgery, The University of Tokyo, Japan,
3
Department of Orthopaedic Surgery, Keio University School of Medicine, Japan1

2P-485

RNF20/BRE1a regulates proliferation and differentiation of GBM
cancer stem-like cells
Kenny Daun1), Naoko Morimura1), Kazuhiko Nozaki2), Kenji Tanigaki3),
Seiji Hitoshi1)

Department of Integrative Physiology, Shiga University of Medical Science, Japan,
Department of Neurosurgery, Shiga University of Medical Science, Japan, 3ResearchInstitute Shiga Medical Center, Japan1
2

2P-486

Analysis of the mechanism regulating intercellular transport ofsilencing RNA in C. elegans
Keita Yoshida, Sawako Yoshina, Yuji Suehiro, Shohei Mitani

Department of Physiology, Tokyo Women's Medical University School of Medicine,Japan

2P-487

Swallowing reflex-inducible stimulations in rats
Izumi Ujihara, Suzuro Hitomi, Kentaro Ono

Division of physiology, Kyushu Dental University, Japan

2P-488Intracellular Ca2+ source for SK channels in cartwheel cells of themouse dorsal cochlear nucleus
Tomohiko Irie

Division of Pharmacology, National Institute of Health Sciences, Japan

2P-489Investigation into functions and molecular mechanisms of hesperetinon human cancer cells
Yukari Ogawa1), Akiyoshi Shiroto1), Kenta Suzuki1), Masami Nishina2),
Shu-ichi Watanabe3), Kazunori Yoshimura1,3)

1
Fac Health Sci, Nihon Inst Med Sci, Japan, 2Biomed Res Ctr, Fac Med, Saitama Med Univ,
Japan, 3Dept Physiol, Fac Med, Saitama Med Univ, Japan

2P-490STARD10 promotes lipid droplet formation cooperatively with
LPCAT1
Masanori Ito, Taichiro Tomida, Yoshinori Mikami, Daisuke Ohshima,
Satomi Adachi-Akahane
Department of Physiology, Faculty of Medicine, Toho University, Japan

2P-491ATP dependent H+transport in endoplasmic reticulum membrane
Yoshimichi Murata, Yoshio Maruyama

Department of Physiology, Graduate school of Medicine, Tohoku University, Japan

2P-492Highly localized pH sensing on the outer membrane of cells using
surface enhanced Raman spectroscopy
Molecular & Cellular Biology: Cellular Physiology (2)Leonardo Puppulin1), Shigekuni Hosogi1,2), Hideo Tanaka3),
Yoshinori Marunaka1,4,5)
Department of Molecular Cell Physiology, Kyoto Prefectural University of Medicine,Japan, 2Department of Clinical and Translational Physiology, Kyoto Pharmaceutical
University, Japan, 3Department of Pathology and Cell Regulation, Graduate School of
Medical Sciences, Kyoto Prefectural University of Medicine, Japan, 4Research Center for
Drug Discovery and Pharmaceutical Development Science, Research Organization of
Science and Technology, Ritsumeikan University, Japan, 5Research Institute for ClinicalPhysiology, Kyoto Industrial Health Association, Japan1

2P-493High-level of homocysteine alters cell viability of endothelial cell andMüller cell1
School of Medicine, Fu-Jen Catholic University, Taiwan, 2Department of Life Science,
Fu-Jen Catholic University, Taiwan, 3Department of Ophthalmology, School of Medicine,National Yang-Ming University, Taiwan, 4Department of Ophthalmology, Taipei Veterans
General Hospital, Taiwan

2P-494

Expression of Mechanosensitive Ion Channel in Osteoblasts

Sayoko Nagai1), Asuka Higashikawa2), Sadao Ooyama2), Maki Kimura2),
Yoshiyuki Shibukawa2), Akira Katakura1)
Department of Oral Pathobiological Science and Surgery, Tokyo Dental College, Japan,
Department of Physiology, Tokyo Dental College

12

2P-495

Exploratory search for therapeutic target genes to cure MELAS using
CRISPR activation
Hitomi Kaneko, Takeshi Chujo, Fan-Yan Wei, Kazuhito Tomizawa

Department of Molecular Physiology, Faculty of Life Sciences, Kumamoto University,Japan

2P-496The effect of benzodiazepine on proliferation and survivals of CNS
cells
Tomonori Furukawa1), Shuji Shimoyama1,2), Yoshiki Ogata1), Shinya Ueno1,2)

Department of Neurophysiology, Hirosaki University Graduate School of Medicine,Japan, 2Research Center for Child Mental Development, Hirosaki University Graduate
School of Medicine

1★ 2P-497(Y-34)The impact of DNA methyltransferase 3A in erythrocytic differ­entiation
Eric Chang-Yi Lin, Po-Shu Tu, Hsiao-Wen Chen, Yuan-I Chang
Department of physiology, National Yang-Ming University, Taiwan

2P-498

Calcium response in human synovial cells induced by shear stress innormal and rheumatoid arthritis
Yu Okumura1,2), Keiji Asada3), Miyako Takaki1)

1
Department of Orthopaedic Surgery, Nara Medical University, Japan, 2Department of
Physical Therapy, Faculty of Human Science, Osaka University of Human Science, Japan,
3
Department of Physical Therapy, Faculty of Health Science, Suzuka University of
Medical Science, Japan

Adaptation, Environment & Evolution (2)2P-499Relationship between dehydration and amount of drinking water
before shifts : a preliminary study
Ryutaro Kase, Yuji L Tanaka, Hisayoshi Sugawara, Erina Matsushima,
Masatoshi Komiyama, Ayumi Amemiya

Molecular & Cellular Biology: Cellular Physiology (2)/Adaptation, Environment & Evolution (2)DAY 3

Yih-Jing Lee1), Yi-Ching Chen1,2), Hsin-Jen Hsieh1,2), Chia-Ying Ke1),
Ni Tien1), Po-Kang Lin3,4)

★ 2P-500(Y-35)

Department of Nursing Physiology, Graduate School of Nursing, Chiba University,
Japan

Hearing status of Rickshaw’s drivers in Karachi, Pakistan assessedby Pure tone audiometry
Muhammad Adnan Kanpurwala1,2), Furqan Mirza3)
1
Department of Physiology, Karachi Institute of Medical Sciences, Pakistan, 2Departmentof Physiology, University of Karachi, 3Department of Health Management, Institute ofBusiness Management

2P-501

A corticohypothalamic neural pathway that drives sympathetic
responses to psychological stressNaoya Kataoka, Keisuke Nakajima, Kazuhiro Nakamura

Department of Integrative Physiology, Nagoya University Graduate School of Medicine,Japan

2P-502

Expanded plasma volume after a bout of exercise increases
erythropoietin secretion to hypoxia
Kazunobu Okazaki1,2), Ryosuke Takeda1), Daiki Imai1,2), Eriko Kawai2),
Akemi Ota2), Kosuke Saho2), Emiko Morita2), Yuta Suzuki1,2),
Kazushige Goto3), Hisayo Yokoyama1,2),

1
Research Center for Urban Health and Sports, Osaka City University, Japan, 2Departmentof Environmental Physiology for Exercise, Osaka City University Graduate School of
Medicine, Japan, 3Faculty of Sport & Health Sciences, Ritsumeikan University, Japan

2P-503The effect of aging on event-related potentials during mild-hyper­
thermia

Akemi Ota1,2), Ryosuke Takeda3), Daiki Imai2,3), Eriko Kawai2), Kosuke Saho2),
Emiko Morita2), Yuta Suzuki2,3), Hisayo Yokoyama2,3), Kazunobu Okazaki2,3)

Faculty of Biomed. Eng., Osaka Electrocommun Univ., Japan, 2Dept. of Environ. Physiol.
for Exercise, Osaka City Univ. Grad. Sch. of Med., Japan, 3Res. Ctr. for Urban Health &Sports, Osaka City Univ., Japan1

2P-504

Thermosensory changes in heat resistant tadpoles of Ryukyu kajika
frogs inhabiting hot springs
Shigeru Saito1,2,3), Claire T. Saito1,2), Takeshi Igawa4), Shohei Komaki5),
Makoto Tominaga1,2,3)

1
Division of Cell Signaling, National Institute for Physiological Sciences, Japan, 2Thermal
Biology Group, Exploratory Research Center on Life and Living Systems (ExCELLS),
Japan, 3Department of Physiological Sciences, SOKENDAI (The Graduate University for
Advanced Studies), Japan, 4Amphibian Research Center, Hiroshima University, Japan,
5
Division of Biomedical Information Analysis, Iwate Tohoku Medical Megabank
Organization, Japan

2P-505

Influence of combined stimulus of cold, hypoxia and dehydration
status on thermoregulation in rats
Tadashi Uno, Tatsuya Hasegawa, Masahiro Horiuchi

Division of Human Environmental Science, Mount Fuji Research Institute, Japan

2P-506

Possible central mechanism of acquired heat tolerance in exercisetrained rats
Kentaro Matsuzaki1), Masanori Katakura2), Naotoshi Sugimoto3),
Eri Sumiyoshi1), Toshiko Hara1), Osamu Shido1)

Department of Environmental Physiology, Faculty of Medicine, Shimane University,
Japan, 2Department of Nutritional Physiology, Faculty of Pharmaceutical Sciences, Josai
University, Japan, 3Department of Physiology, Graduate School of Medical Science,
Kanazawa University, Japan
1

Adaptation, Environment & Evolution (2)2P-507

Estimation of basal body temperature from breast skin temperatureduring sleep
Shuri Marui, Kei Nagashima

Faculty of Human Sciences, Waseda University, Japan

2P-508

Wearable patch-type sensors for core temperature monitoring by amodified dual-heat-flux method
Ken Tokizawa1), Tatsuo Oka1), Hirofumi Tsuchimoto2), Toru Shimuta2)

1
National Institute of Occupational Safety and Health, Japan, 2Murata ManufacturingCo., Ltd,

2P-509Ruey-Ming Liao1,2,3), Shuo-Fu Chen1,2), Chuen-Yu Chuang1,2),
Chih-Chang Chao2,3)1
Department of Psychology, National Cheng-Chi University, Taiwan, 2Institute of
Neuroscience, National Cheng-Chi University, Taiwan, 3Center for Mind, Brain andLearning, National Cheng-Chi University, Taiwan

2P-510The effect of environmental temperature on spontaneous exercise inmice
Yuta Mausda1), Shuri Marui2), Ken Tokizawa3), Issei Kato1), Kei Nagashima2)

1
Department of Human sciences, Waseda University, Japan, 2Faculty of Human
Sciences, Waseda University, Japan, 3National Institute of Occupational Safety and
Health, Japan

2P-511

Function of polyunsaturated fatty acid in thermoregulation
Takuto Suito, Kohjiro Nagao, Naoto Juni, Masato Umeda

Department of Synthetic Chemistry and Biological Chemistry, Graduate School ofEngineering, Kyoto University, Japan

2P-512

Cold induced sleep-related sympathovagal imbalance and sleep
fragmentation in rats
Cheng-Han Wu1,2), Terry B.J. Kuo1,2,3,5,6), Chieh-Wen Chen1,2),
Yu-Syuan Liou1,2), Kuan-Liang Kuo4,7), Cheng-Hung Chung1,2),
Yu-Ting Lin1,2), Cheryl C.H. Yang1,2,3,5)

1
Institute of Brain Science, National Yang Ming University, Taiwan, 2Sleep ResearchCenter, National Yang Ming University, Taiwan, 3Brain Research Center, National Yang
Ming University, Taiwan, 4Institute of Bio Medical Informatics, National Yang-Ming
University, Taiwan, 5Department of Education and Research, Taipei City Hospital, Taiwan,
6
Graduate Institute of Biomedical Informatics, College of Medical Science andTechnology, Taipei Medical University, Taiwan, 7Family Medicine Department, Taipei
City Hospital Ren-Ai Branch, Taiwan

2P-513A mouse model that can evaluate fever and hyperalgesia due toperipheral inflammation
Hiromu Kitagawa1), Takae Ibuki2), Kiyoshi Matsumura1)

Graduate School of Engineering, Osaka Institute of Technology, Japan, 2Department ofAnesthesiology, Kyoto Prefectural University of Medicine, Japan1

2P-514

Induction of long-term torpor by enhancing the adenosine receptor
signal via PPARs activation
Miho Sato-Hashimoto, Hiroshi Ohnishi

Department of Laboratory Sciences, Gunma University Graduate School of Health
Sciences, Japan

Adaptation, Environment & Evolution (2)DAY 3Operant behaviors affected by warm ambient temperature are taskdependent and hippocampus involved

2P-515

Involvement of the vagus nerve in autonomic thermoregulation
responses induced by TRPM8 agonist
Noriyuki Mori1,2), Tomomi Urata2), Tsutomu Fukuwatari2)

Department of Food Science and Nutrition, Doshisha Women's College of Liberal Arts,
Japan, 2Department of Nutrition, the University of Shiga Prefecture, Japan1

2P-516

Aurelia Aurita venom evoke hyperpolarization and SOCS1 expression
in toad urothelium membrane
Yang Wang1,2), Han Wang1), Linghua Piao1), Tong He1), Lingfeng Gao1)

1
Faculty of Basic Medicine and Life Sciences, Hainan Medical College, China, 2Laboratoryof Extreme Environment Sports Medicine, Hainan Medical College

2P-517

Withdrawn

2P-518

Seasonal differences in cardiac autonomic nervous activity during
exercise in obese men
Maki Sato1,2), Hisaki Hayashi1), Tatsunori Ikemoto3), Takahiro Ushida3),
Dominika Kanikowska4), Satoshi Iwase1), Motohiko Sato1)

Department of Physiology, Aichi Medical University, Japan, 2Institutional Research,
Aichi Medical University, Japan, 3Institute of Physical Fitness, Sports Medicine andRehabilitation, Aichi Medical University, Japan, 4Department of Pathophysiology,
Poznan University of Medical Sciences, Poland
1

Genomics & Biodiversity
2P-519

PAI-1 is crucial in osteoblastic differentiation of mesenchymal stem
cells
Yoshimasa Takafuji, Kohei Tatsumi, Masayoshi Ishida, Naoyuki Kawao,
Kiyotaka Okada, Osamu Matsuo, Hiroshi Kaji

Department of Physiology and Regenerative Medicine Kindai University Faculty of
Medicine, Japan

2P-520Regenerative capacity of stem cells in the skeletal muscle:
Comparison between human, mouse and pig
Tetsuro Tamaki1), Ippei Yamato2), Shuichi Soeda1), Yoshiyasu Uchiyama3)

Department of Human Structure and Function, Tokai University School of Medicine,Japan, 2Department of Medical Education, Tokai University School of Medicine,3
Department of Orthopedics, Tokai University School of Medicine
1★ 2P-521(Y-37)

Alpha-5 integrin mediates simvastatin-induced osteogenesis ofbone marrow mesenchymal stem cells
Pei Lin Shao1), Shun Cheng Wu2,3), Zih Yin Lin2,3), Chau Zen Wang2,3),
Chung-Hwan Chen2), Mei-Ling Ho2,3)1
Department of Nursing, Asia University, Taiwan, 2Orthopaedic Research Center, Collegeof Medicine, Kaohsiung Medical University, Taiwan, 3Department of Physiology, Collegeof Medicine, Kaohsiung Medical University, Taiwan

2P-522

Molecular network search for bcl-7 related factors

Luna Izuhara1), Sawako Yoshina1), Sayaka Higuchi2), Yuji Suehiro1),
Shohei Mitani1,2)
Department of Physiology, Tokyo Women's Medical University School of Medicine,Japan, 2Tokyo Women’s Medical University Institute for Integrated Medical
Sciences,Japan

1

Adaptation, Environment & Evolution (2)/Genomics & Biodiversity

2P-523

Platelet-rich plasma supplementation increase CD34 hematopoietic
stem cell proliferation in vitro

Imelda Rosalyn Sianipar1), Beryl Alodia2), Yosafat L Prasetyadi2),Retno Wahyu Nurhayati3), Gita Pratama4,5), Radiana Dhewayani Antarianto6,7)

1
Department of Medical Physiology, Universitas Indonesia, Indonesia, 2Undergraduate
program in Medicine, Faculty of Medicine, Universitas Indonesia, Indonesia, 3Stem Celland Tissue Engineering Research Cluster IMERI, Faculty of Medicine, Universitas
Indonesia, Indonesia, 4Department of Obstetry and Gynecology, Faculty of Medicine
Universitas Indonesia, Indonesia, 5Integrated Service Unit and Technology Stem Cell
National General Hospital Ciptomangunkusumo, Indonesia , 6Department of Histology,
Faculty of Medicine, Universitas Indonesia, Indonesia, 7Doctoral program in Biomedical
Science, Faculty of Medicine, Universitas Indonesia, Indonesia

Identifying heterogeneity of ground state pluripotency in mouseembryonic stem cells
Kyoji Horie, Junko Yoshida

Department of Physiology II, Nara Medical University, Japan

2P-525

Bioactive Ligands-Based Neuronal Reprogramming of Human
Dedifferentiated Fat Cells
Rei Nakano1,2), Yoshiyuki Shibukawa3), Koichiro Kano4), Taro Matsumoto5),
Hiroshi Sugiya2)

Laboratory for Cellular Function Conversion Technology, RIKEN Center for Integrative
Medical Sciences (IMS), Japan, 2Laboratory of Veterinary Biochemistry, College of
Bioresource Sciences, Nihon University, 3Department of Physiology, Tokyo Dental
College, 4Laboratory of Cell and Tissue Biology, College of Bioresource Sciences, Nihon
University, 5Department of Functional Morphology, Division of Cell Regeneration andTransplantation, Nihon University School of Medicine
12P-526

Determining Deubiquitinating Enzymes Regulating Adipose Derived
Mesenchymal Stem Cells Senescence
Dong Hyeon Lee1), Soonchul Lee2)

Department of Physiology, CHA University School of Medicine, Republic of Korea,
Department of Orthopaedic Surgery, CHA Bundang Medical Center, CHA University
School of Medicine, Republic of Korea

12

2P-527

Grafted hypothalamic Neurons from Mouse ES Cells survived in
hypothalamus or pituitary
Miho Kawata1), Yu Kodani1), Hidetaka Suga2), Yoko Kaneko1),
Akira Nakashima1), Hiroshi Nagasaki1)

Department of Physiology, School of Medicine, Fujita Health University, Japan,
Department of Endocrinology and Diabetes, Nagoya University Graduate School of
Medicine

12

2P-528

Effects of beta 3-adrenergic receptor gene Trp64Arg mutation on
high-fat sweet food preference
Kei Watanabe1), Guang Hong2), Kanako Tominami1), Kazushi Hirosawa1),
Yuki Watabe1), Youhei Hayashi3), Tada-Aki Kudo1)

Division of Oral Physiology, Tohoku University Graduate School of Dentistry, Japan,
Liaison Center for Innovative Dentistry , Tohoku University Graduate School of dentistry
Japan, 3Cell Resource Center for Biomedical Research, Institute of Development, Aging
and Cancer, Tohoku University, Japan1
2★ 2P-529(Y-38)

Vitamin D Receptor Polymorphism Fok1 and Chest X-ray in
Tuberculosis Patients of Batak Ethnic
Debby Mirani Lubis1), Seri Rayani Bangun2), Yahwardiah Siregar2),
Genomics & Biodiversity

DAY 3

2P-524

Bintang YM Sinaga3)
Department of Physiology, University of Muhammadiyah Sumatera Utara, Indonesia,
Biomedical Science, University of North Sumatera, 3Pulmonology Department,
University of North Sumatera
1
2

Education
2P-530Quick eating elevates blood glucose level, a practice for registereddietitians students
Masaru Ishimatsu, Junko Machidori, Kanako Nanashima, Haruka Suzuki,
Kazue Kuno
Fuculty of Health and Nutrition Sciences, Nishikyushu University, Japan

2P-531

Design and Application of Blended Learning in the Teaching Reformof Medical Functional Experiments
Ran Chen, Xiaofang Fan, Ping Wang, Feng Xue, Jianshe Ma,
Yongsheng Gong

School of Basic Medical Sciences, Wenzhou Medical University , China

2P-532

Active learning on topics related to physiology by the first year
medical students
Eriko Daikoku

Department of Physiology, Osaka Medical College, Japan

2P-533Do 1st-year medical students’ knowledge,attitudes & physical activity
affect their physical fitness?
Yhusi Karina Riskawati1), Narulita Septi Ailina2), Saptadi Yuliarto3),
Christyaji Indradmojo4)

Departement of Physiology, Faculty of Medicine, Universitas Brawijaya, Indonesia,
School of Medicine Faculty of Medicine, Universitas Brawijaya, Indonesia, 3PediatricDepartment of Faculty of Medicine, Universitas Brawijaya, Indonesia, 4Medical Faculty,
Maulana Malik Ibrahim Islamic State University Malang
12

2P-534Multiple intelligence and its relationship with academic achievementsof medical students
Nirmala Limbu1), Nidesh Sapkota2), Priza Subedi1)

Department of Basic & Clinical Physiology, B. P. Koirala Institute of Health Sciences,
Nepal, 2Department of Psychiatry, B. P. Koirala Institute of Health Sciences, Nepal

1★ 2P-535(Y-39)

Flipped classroom in Faculty of Medicine Universitas Indonesia: apersonal experience
Sophie Yolanda
Department of Medical Physiology, Faculty of Medicine Universitas Indonesia,
Indonesia

2P-536

Withdrawn

2P-537

Across-instructor divergence in scoring on practice reports in theorthoptics education with rubrics
Haruo Toda, Hokuto Ubukata, Noriaki Murata, Fumiatsu Maeda,
Haruki Abe

Department of Orthoptics and Visual Sciences, Niigata University of Health and Welfare,Japan

2P-538The relationship between anemia, dietary habits and subjective
symptoms of females
Genomics & Biodiversity/Education

Noriko Takahashi
Showagakuin Junior College, Japan

2P-539Comparison of two models which explain negative feedback at ajunior college
Masato Shibuya1,2), Kaname Higuchi1,2), Kei Tajima1,2), Mieka Inagaki1,2)

1
Department of Physiology, Kagawa Nutrition Junior College, Japan, 2Life Science
Education Sharing Group

Alternative Medicine (2)2P-540A new criterion for inclusion/exclusion from acupuncture treatment
with blood pressure balance★ 2P-541(Y-40)

Faculty of Health Sciences, Kansai University of Health Science, Japan

The Anti-depressive and the Involvement of ERK Pathway ofElectroacupuncture on Depression Model
Shao-Yuan Li1), Pei-Jing Rong1,2), Xiao Guo1)
Institute of Acu.-Moxi., China Academy of Chinese Medical Sciences, China,
Guangzhou University of Chinese Medicine

1
2

2P-542

Vasorelaxant induced by cucurbitacin B 3-oxime 22,24-dihydro­
isoxazole in rat thoracic aorta
Chainarong Tocharus1), Pimchanok Mungmuang1), Jiraporn Tocharus2),
Parichat Suebsakwong3), Apichart Suksamrarn3)

1
Department of Anatomy, Chiang Mai University, Thailand, 2Department of Physiology,
Chiang Mai University, Thailand, 3Department of Chemistry and Center of Excellence forInnovation in Chemistry, Ramkhamhaeng University

2P-543

Pomegranate Juice Protects Rat Skeletal Muscle from Ischemia/
Reperfusion Induced-Oxidative Stress
Kusuma Ruamthum, Rungrudee Srisawat

School of Preclinic, Institute of Science, Suranaree University of Technology, Thailand

2P-544Ex-vivo investigation on the anti-coagulation effect of a Chinese
medicinal herb
Ellie SM Chu, Ly Ho, Ricky Wk Wu

School of Medical and Health Sciences, Tung Wah College, China

2P-545

Nutmeg Extract Increases Skeletal Muscle Mass in Ageing Rats andInhibition of Autophagy
Yuni Susanti Pratiwi1,2), Ronny Lesmana1,2), Hanna Goenawan1,2),
Nova Sylviana1,2), Setiawan Setiawan1,2), Vita Murniati Tarawan1,2),
Keri Lestari3), Rizky Abdullah3), Lazuardhi Dwipa5), Ambrosius Purba1,2),
Unang Supratman2,4)Division of Physiology, Department Basic Medical Science, Faculty of Medicine
Universitas Padjadjaran, Indonesia, 2Central Laboratory, Universitas Padjadjaran, 3Facultyof Pharmacy, Universitas Padjadjaran, 4Department of Chemistry, Faculty ofMathematics and Natural Sciences, Universitas Padjadjaran, 5Department of Internal
Medicine, Faculty of Medicine-Hasan Sadikin Hospital, Universitas Padjadjaran
12P-546

Analgesic effect of isoliquiritigenin on oral ulcer-induced pain byblocking of Nav channels
Yuichi Miyamura1,2), Suzuro Hitomi1), Izumi Ujihara1), Kiyoshi Terawaki3),
Yuji Omiya3), Yasuhiro Morimoto2), Kentaro Ono1)
Education/Alternative Medicine (2)DAY 3Mayumi Watanabe, Zaigen Oh

1
Division of Physiology, Kyushu Dental University, Japan , 2Division of Dentomaxillofac
Radiology, Kyushu Dental University, Japan , 3Tsumura Kampo Research Laboratories,
Kampo Research & Development Div, Tsumu ra & Co., Japan

2P-547

Flos Magnoliae suppresses CD4+ T lymphocyte activation via storeoperated calcium entry
Joo Hyun Nam1,2), Hyun Jong Kim1,2), Yu Ran Nam1,2), Woo Kyung Kim2,3)★ 2P-549(Y-41)

1
Department of Physiology, Dongguk University, South Korea, 2Channelopathy
Research Center, Dongguk University College of Medicine, South Korea, 3Department
of Internal Medicine, Dongguk University College of Medicine, South Korea

Malaysian Tualang Honey Protects Endothelial Barrier Integrity from
Insults by Hydrogen Peroxide
Yoke Keong Yong1), Kogilavanee Devasvaran1), Jun Jie Tan2)
Department of Human Anatomy, Faculty of Medicine and Health Sciences, Universiti
Putra Malaysia, Malaysia, 2Advance Medical and Dental Institute, Universiti Sains
Malaysia, Malaysia

12P-550Acetophenone dimers from Acronychia pendunculatainduce anapoptotic effect on human leukaemia cells
Takuya Matsui1), Chihiro Ito2), Tian-Shung Wu3), Masataka Itoigawa4)

1
Department of Physiology, Aichi Medical University, Japan, 2Faculty of Pharmacy, Meijo
University, Japan, 3Department of Chemistry, National Cheng Kung University, Taiwan,
4
School of Sports and Health Science, Tokai Gakuen University, Japan

2P-551

Purple rice husk extract preserves mitochondrial integrity andreduces diabetic kidney injury
Orawan Wongmekiat1), Narissara Lailerd2), Anongporn Kobroob3),
Wachirasek Peerapanyasut1)

Renal Physiology Unit, Department of Physiology, Faculty of Medicine, Chiang Mai
University, Thailand, 2Nutrition and Exercise Unit, Department of Physiology, Faculty of
Medicine, Chiang Mai University, Thailand, 3Division of Physiology, School of Medical
Science, University of Phayao, Thailand
1

2P-552

Addition of hexachlorocyclohexane provokes insulin resistance in
3T3-L1 mature adipocytes
Amire Alimu, Junetsu Ogasawara, Takahiko Yoshida

Department of Hygiene, Asahikawa Medical University, School of Medicine, Japan

Alternative Medicine (2)