Mystery ORF genes in Covid Vaccine
The following is taken from Spider webs in the Pfizer closet - by Anandamide (substack.com)
Pfizer failed to identify the 2nd largest ORF (Open Reading Frame) in the plasmid. This is the mystery ORF of1252 amino acids described by Beaudoin et al. The protein sequence of the Mystery ORF is given below –>Mystery_ORF_Under_Pfizer_SpikeMQYQLESSCVVQFHALQHGLRIVLVELAAAATATTALQAATAAGHATQHDCDHHDGNQSGDKAQPDVPGPLDVLLVLPQFLQVDQALVQILGHLVQPVDLFLDVHDAGIDSADIAQVHVGACVVLKVLVQFLFEAVQLGLQRVVHGIVHNADHDVAVARHEGVVGGDDLGLVEVPLCHEPMGAVGHEHAFSRKVGFAVVADGWSGGEILLLSGHICHVQKHHAVRGRLREAHQVVALAAKVHSLALAQHTLRHLGGGQIGRGSNLGGSDQLLGHVCLEALQSACDQSVDLHLGLRRVQSAQDIVQHRADGAELGGQLLDQGVQCLGIVVDHVLQLSQGACCAAQAVLDLADGAVELVGDQLLVLVQHILGHSDAVEPVGHLHSKGDLQSGACSKCPAACDCAGQQGRCVLGDHLIGQQRRQHCQSVKLLGANQIPGGNVAQTIAILLDEAGVGQCHFVEQQVLDEAPLAGLARIGQNLAEIEAAEVLDRRGLVDLLHLGEHLLGVLVLFHGDPCQGSFQLGAEAAVLQQQVGALGGIAADVHGAVHAGLGHGHRQDLCGHADGEVGGDSDRVVGVGHAVLGAQRHCVGNDALAGHASGSPVALCLCLVAGADSSADGDVALVAIVHVLGSDQTAGSGLKHIAAGGVHPPCRCQLIGVNGHGHFGTVHALVQHCHLIAGVGARGDHRHSAEAARGDVQDFQCLGISNGVCGIGDIPAKLLEWQELLVALCQHAGAGQAVEVEVHAFVLHEIGAFLRAAHCGRGMQQFEAQHHHSVGLVAHAVCGPKAVGLQWEVAVHACHAVTRLVAGLIDLGGDVPLEGLQIGLPEQPVPVIVVAADFGVQLVAVPGNHTAGEVVGQLVVVVGDVACLSRGNLPHFVSPDHEAVGVHVCEAQVVQLGRGHAVALECEEGGEVVQHGVVGHAIADPLPVPGVHRGESGGIEHLVEGAQIGDIGEPHDGFGGLHPEVAGLVDALFHGEGLQGALCLAQRIQSTIHGVGDGAVLVVLQQEGSRLQVAHIVSGGTSCPSAAAIARCQVASVQGQQCLKPGDVDADGQIHQGFQSREALRQIPAEVDRGVLAVDLEVAVDVLKHELAQVLEVALLAFQVHQERLGHVLEGAVVGAAVHPELAFHPALVVLVVVDVQEGVVAELELAHFDDHVGGVVHDQQALGLAVQCGAEDPASDDVGLLGAGKVHPVVEGQHGVVESLGAIGAGDGVEPGHVAEERQEQVLGRVQHAGSEHLVGVVHASGKAVGVORFs are painted in Green and Gold in the plasmid map below.
This large 1252 amino acid ORF wasundisclosed and this violates FDA andWHO guidelines.

Using Uniprot to Identify What this ORF Does
What is the Mystery ORF in Green on the opposite strand of Spike? Why was this ORF never disclosed despite
the WHO and FDA regulation claiming all ORFs need to be identified? This seems like a major omission as
FDA can’t claim this is of no consequence if regulations demand all ORFs be disclosed.
Ananthamide found that the Mystery ORF's closest hit is to a protein involved in silk.

Other hits with lower E-values are to Collagen and Fibroin.
Ananthamide got no hits when he used blastP to search for this sequence in the NCBI database. It only
showed up in UniProt.
I checked Uniprot to confirm Ananthamide’s finding. I input the above sequence here - Tool results |UniProt
The top result was Spidroin as reported.

Analysis of Mystery ORF Region Using AmyloGram Tool

AmyloGram (uni.wroc.pl) shows that this ORF sequence is amyloidogenic. If the cells lining bloodvessels start manufacturing this amyloid, then the blood vessels will slowly fill with amyloid fibrils
and the flow of blood will be gradually impeded.

Analysis of Pfizer Spike Region Using AmyloGram Tool

So BOTH the ORF sequence AND the SPIKE sequence will result in the production of amyloid. In other words– as surely as the vaccine RNA generates spike protein (its intended purpose), it will also generate amyloid (ahidden intended purpose?)Independent research confirms that Spidroin generates amyloid
Spider Silk Protein Forms Amyloid‐Like Nanofibrils through a Non‐Nucleation‐Dependent
Polymerization Mechanism ‐ Qi ‐ 2023 ‐ Small ‐ Wiley Online Library
Amyloidogenic nature of spider silk (wiley.com)

Note that the spiridon sequence forms amyloid-like fibrils rapidly at 37 degrees Celsius. So it is highly
amyloidogenic.

Conclusion
Given the deliberate undisclosed inclusion of an amyloid producing sequence, as well as the inclusion of thespike sequence that is also amyloidogenic, there is a distinct possibility that amyloid formation may be an
intended effect of the Covid vaccine.