BOOK OF ABSTRACTS | 12th European Congress of Integrative Medicine · 1st International Symposium on Integrative Health and Education

1

II National Congress of Health and Integrative Medicine

BARCELONA
13-15 September 2019

1st

International Symposiumon Integrative Healthand Education
TARRAGONA
12 September 2019

Book of abstracts
Comissió infermeria integrativa

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BOOK OF ABSTRACTS | 12th European Congress of Integrative Medicine · 1st International Symposium on Integrative Health and Education

Edited by
Universitat Rovira i Virgili c/ de l’Escorxador, s/n 43002 Tarragona(Spain)
1st edition: September 2019 ISBN 978-84-8424-807-1
This work is licensed under the Creative Commons
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BOOK OF ABSTRACTS | 12th European Congress of Integrative Medicine · 1st International Symposium on Integrative Health and Education

Dear colleagues from all over the world in Integrative Medicine

It is a great honor to present the book of abstracts for the XII European Integrative Medicine
Congress, co-organized by the European Society of Integrative Medicine and the Spanish Society of Health and Integrative Medicine.
First of all, and from the ESIM and SESMI boards we would like to thank everyone for being
here and for your great work to spread and improve the principles and application of Integrative Medicine.
Integrative Medicine does not pretend to be an alternative to anything or anyone. Its primary objective is to improve medicine, its approach, its vision from other points of view, its
teamwork, the understanding of human being in a global concept, work in cooperation withdifferent professionals using respectful and less possible harmful methods. And, above all, having always the patient at the center of the process, keeping him well informed and respecting
his decision-making power.
Recently, and because of some statements, campaigns and law proposals from some government’s administration, we are aware that, either they have not understood us, or we have notbeen able to explain clearly enough the concept of Integrative Medicine.
In this congress we want to deepen our knowledge and spread the bases and contents ofIntegrative Medicine.
We will do it from a very clear slogan: “Together in Integrative Medicine”
At a time that moving towards sustainability and ecology is essential to keep our planet alive,
a respectful, natural and less medicalized medicine is a must.
In this book of abstracts, you will find summaries for more than 80 papers from relevant
Integrative Medicine world professionals, 80 free communications and 100 accepted posters. I
will not highlight any of them, as a collective we are all essential to improve medicine throughIntegrative Medicine.
This congress has been an enormous coordination effort and cooperation work between
ESIM and SESMI boards and the scientific and organization committees and secretary, as well.
We hope that it will be useful for all participants coming from all over the world.
For us it has been an exciting work full of joy, joy that now we want to share with all of you.

“Together in Integrative Medicine”
		A very warm welcome to Barcelona!

Dr. Isabel Giralt
President of Integrative Medicine Congress
Barcelona 20193

SUMARY

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BOOK OF ABSTRACTS | 12th European Congress of Integrative Medicine · 1st International Symposium on Integrative Health and Education

BOOK OF ABSTRACTS | 12th European Congress of Integrative Medicine · 1st International Symposium on Integrative Health and Education

5

SUMMARY
00. Introduction
Plenary
Plenary session I: Congress
opening. Research
01 Overall situation and future of Integrative Medicine in Germany
Brinkhaus, B

12 Pharmacogenetics,
Sabater-Tobella, JPlenary Session II: Main
auditorium. Clinical care.
13 Integrating acupuncturetechniques into the treatment of COPD
Fernández, C

02 Current situation and research in integrative medicine in the US
Kreitzer, MJ

14 Aromatherapy for pain
management and anxiety
during the first stages oflabour in a public Spanish
hospital
La Rosa, C

03 Integrative Medicine: theItalian situation
Rossi, E

15 Cultivating wellbeing in ourlives and organizations
Kreitzer, MJ

04 Integrative Medicine inAustralia: Research andevolution
Prof Avni Sali

16 Ayurveda to prevent, control and cure chronic diseases
Gramminger, H

05 Present and future of Integrative Medicine in Japan
Suzuki, K
06 Integrative Medicine: Current scientific progress in
Spain
Gascón, P
DISCUSSION
07 Environmental oncology: A
forward-looking approachin the prevention andtreatment of cáncer.
Eres, NKEY NOTE
17 Vitamin C and cancer: Towards an integrative pathway of molecular researchand clinical practiceAguilera, O

Plenary Session III: Integrative Medicine and Traditional Medicine

22 Integrative Medicine andsteps of treatment
Crespo de la Rosa, JC
DISCUSSION PANEL
23 Immunity or the importance of the first thousanddays of life
Begara, M
24 The contribution of CAM to
reduce antibiotic use and
AMR
Baars, E
25 What can reflexology do
for children with cancer?
Carrasco, B
26 Biological Treatments for
Autism and PDD
Shaw, W
KEY NOTE
27 Atypical risk factors in cardiovascular disease: early
detection is not prevention
Mejias, S
SYMPOSIUM
28 Neural Therapy, Vegetative
Nervous System and Fascia: broad-spectrum regulatory therapy.
Vinyes, D

18 Integrative Medicine in a
Spanish Public Hospital
Abadia, C

29 Integrative odontology: themouth’s impact on bioregulation
López, M

08 Do you live in a healthy
space?
León, P

19 The Future of Comprehensive Patient Care
Thangavelu, M

30 Ozonotherapy in human papillomavirus (HPV) infection
Schwartz, A

09 Environmental toxins as
triggers of multiple pathologies.
Muñoz-Calero, P

20 Integrative oncology: European and international
perspectives
Rossi, E

10 Resilient and healthy cities.
Santana, C

21 Vitamin C from micro to
macro essential nutrient:
Changing the paradigm
O’byrne, A

11 Human exposure to endocrine disruptors and theconsequences for health.
Olea, NKEY NOTEROUND TABLE
31 Integrative approach topremenstrual syndrome
Menassa, A
32Fertility and acupuncture
Carvajal, G; Giralt, I
33 Reflexology and assisted
reproduction
Vives, C6

BOOK OF ABSTRACTS | 12th European Congress of Integrative Medicine · 1st International Symposium on Integrative Health and Education

34 Micronutrients and theireffect on fertility
Salgado, C

44Toxic chemicals and theireffects on health
Shaw, W

35 After obstetric violence:
The integration on theagencyBrigidi, S

INTEGRATIVE EXPERIENCES

36 Non-conventional therapies in women with breast
cancer and their relation
with conventional therapies
Santoro, V
ROUND TABLE
37 Científica evidence frommeta-analysis and systematic reviews of complementary therapies in oncology
Abanades, S
38 Comprehensive management of cancer patients
Espinosa, J
39 Make Love Not War: An
integral visión of cancerÁlvaro, T
40 How can we “integrate” an“Integrative Oncology” Division into a Hospital?
Gascón, P

Plenary session IV: Biological Practice. Resilience of
the intestinal microbiota:
Impact on health and disease.
41 Controversy around theuse of oral and tropicalradioprotectors in medical
treatment using ionizing
radiation: from basic research to clinical practice.
Montoro, A
42 The efficacy of micro-immunotherapy as a lowdose therapy.
Rigau, J
43 Microbiota and the immune system
De la Puerta, L

45 Complementary Therapies
in Iceland nursing home
Gunnarsdóttir, TJ
46 DietaryTherapy and food incancer. Adjuvant treatment.
Evidence and Strategy
Perez- Calvo, J
47 Ferritin and cancer: How tomake virtue of the problem
Martín, S
48 Shinrin-yoku: Environments
for Purposeful Integrative
Healing
Hansen, M
ROUND TABLE
49 Use of acupuncture in apain unit. A review of over
10 years of practiceMata ,J
50 Auriculopuncture: Treatment of lumbar and pelvic
pain in pregnant womenVas, J
51 Research into atopic dermatitis and allergic rhinitis
Brinkhaus, B
52 A new research direction
from the Asia
Cummings, M
SYMPOSIUM
53 20 years of integrationof homeopathy in the
Public Health System of
the Region of Tuscany
and the experience ofthe Homeopathic Clinicof the Hospital of Lucca(Italy)Rossi, E
54 Research lines in homeopathy: where do we comefrom and where are wegoing?
Díaz, G

55 Practice of homeopathy inFrance. Integration experience at the hospital level
López, Y
KEY NOTE
56 Phytotherapy: relevanceof quality on safety andefficacy
Cañigueral, S
57 Immediate survival versus
healthy longevity
Salgado, C
SYMPOSIUM
58 The importance of anamnesis in Lyme Disease andcoinfections: fundamental
aspects and challenges
that we face
Navarro, C
59 Lyme as a multi-systemic
disease. Setting up a complete functional Lyme protocol
De Sedeleer, P
60 Modern testing for Lymeand coinfections
Dr. Schwarzbach, A

Plenary session V Complementary Therapies andIntegrative Medicine: Theessence of globality
61 The potential and influenceof music on health
Jauset, JA
62 Comprehensive approachto health throught holistickinesiology
Amezaga, MA
63 Sound and the voice in IM
Kistemaker, J
64 Effects of Tai-Chi and Chi
Kong on healthGarcia, D
65 Reiki as a Complementary
Therapy
Fernández-Cervilla, AB

BOOK OF ABSTRACTS | 12th European Congress of Integrative Medicine · 1st International Symposium on Integrative Health and Education

66 Medical Geology. Constributions/perspectives from
Medical Geology
Gimenez-Forcada, E
KEY NOTE The future in integrative health67 Art in the Hospital of the
FutureStefan, N; Willich
68 Integrative Medicine approaches to treatment inpsychiatry
Sendula-Jengic
ROUND TABLE
69 Influences of medical
mushrooms on immune
system functioning: how
they can help us
Pellicer, C
70 Hormesis: Strategic interventions for restoring thestress axis
De la Serna, D
71 Inflammation NOT resolved: the background ofchronic degenerative pathology
O’Byrne, A
72 Neuroinflammation: Anxiety, stress and chronicpainVerdaguer, X
MASTERCLASS
73 How to Get Published Inside tips from the Editors
in Chief and Publisher ofthree international journals
Kemper, K; Robinson, N; Prada, V
74 Posturology in Integrative
healthContribution of Posturology
in the treatment of chronicrachialgias
Villenueve, P
SYMPOSIUM AYURVEDA

75 How Ayurveda treatschronic inflammation
Dr. Vijay Carolin

Pre-workshops
76 Acupuncture. Paediatricacupuncture
77 Wellness and healing
through the voice and thesound
78 Towards a guide for preventing of exposure to endocrine disruptors
79 Myofascial trigger points
and laser therapy
80 Gut microbiota and cancer,
the importance of lifestyles: Designing a project

Oral abstract presentations
List of Posters
ID COM:5602
PS1-1
Title: Mindfulness as a Tool inPrimary Care
ID COM:5754
PS1-2
Title: Naturopathic Treatment
and Complementary Medicine
in Surgical Practice
ID COM:5804
PS1-3
Title: The effect of acupuncture on jaw opening range,
and temporomandibular
joint, and myofascial symptoms in patients with Temporo- Mandibular Disorder(TMD): A Randomized controlled trial
ID COM:5880
PS1-4
Title: Effect of repetitive transcranial magnetic stimulation
on pain and thermal sensitivity in Myofacial Pain Dysfunction syndrome (MPDS)

7ID COM:5881
PS1-5
Title: Implementation of aMulti-Professional Anthroposophic Treatment Concept in
the Geriatrics
ID COM:5960
PS1-6
Title: Pelvic Outlet Syndrome:
A New Integrative Diagnosis
Helps Treatment
ID COM:6004
PS1-7
Title: Cytology-based Circulating-Tumour-Cell (CTC) Screening Test improves detection of
prostate cancer
ID COM:6061
PS1-8
Title: Multimodal Program of
Health Promotion and Qualityof Life based on health theory
by Mokichi Okada: case reports
ID COM:6087
PS1-9
Title: Feasibility and Efficacy
of a Writing to Heal workshop
within a Single Medical Center
ID COM:6090
PS1-10
Title: Remission of cardiorespiratory insufficiency andapnoea syndrome through micronutrition
ID COM:6120
PS1-11
Title: Micronutrition modifies
the evolution of a patient withterminal liver failure
ID COM:6162
PS1-12
Title: Randomised Study, Controlled with Placebo to Evaluate the Neuroprotector Effectiveness of a Food Supplement
In Oxaliplatin Neuropathy
ID COM:5852
PS1-13
Title: Reflexotherapy user profile of a private centre in Catalonia

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BOOK OF ABSTRACTS | 12th European Congress of Integrative Medicine · 1st International Symposium on Integrative Health and Education

ID COM:5907
PS1-14
Title: Ramsay Hunt syndrome
and Acupuncture, a case study
ID COM:5938
PS1-15
Title: Integrating Cupping Therapy in the Management of
Sudden Sensorineural Hearing
Loss in Meniere’s disease: A
Case Report
ID COM:5990
PS1-16
Title: A young man with neurosarcoidosis: Importance ofoxidant status for pathogenesis
and therapy
ID COM:5992
PS1-17
Title: ‘What can I do?’ A young
woman with heart failure
during oncological therapy
ID COM:6005
PS1-18
Title: Kyolic aged garlic extract
improves blood pressure,arterial stiffness and gut microbiota in hypertensives: The
GarGIC trial
ID COM:6059
PS1-19Title: Multimodal Program of
Health Promotion and Qualityof Life based on health theory
by Mokichi Okada
ID COM:6078
PS1-20
Title: Mental illnesses and theuse of integrative therapies.
Systematic review
ID COM:6082
PS2-21
Title: Opinions of Romanian
medical doctors regarding cassic versus online training on
adaptogens
ID COM:6124
PS1-22
Title: Prevalence of health burdens in patients suffering frommalignant diseases revealed bybioresonance – our experience

ID COM:6126
PS1-23
Title: Mineral deficiencies
and food intolerance in patients suffering from chronic
non-communicable diseases
revealed by bioresonance
ID COM:6139
PS1-24
Title: Chickens Breast Meat
Enriched With Propolis And/Or
Bee Pollen – Implications For
Human Health
ID COM:6142
PS1-25
Title: Micotherapy and metabolic control
ID COM:6146
PS1-26
Title: Assessment of the tongue
features associated with breast
cancer using automatic tongue
diagnosis System (ATDS)

ID COM:5973
PS2-5
Title: Neural therapy in thehealing of chronic ulcer ongraft in the scalp
ID COM:5975
PS2-6
Title: Neural therapy in thetreatment of complex regional
pain syndrome (Sudeck’s disease, reflex sympathetic dystrophy)
ID COM:5977
PS2-7
Title: Concomitant use of natural oils and diet change may
help to reduce some eye symptoms in suffering from allergies
ID COM:5978
PS2-8
Title: Clinical Hirudotherapy:
Rheumatoid Arthritis

ID COM:
PS1-27
Title: The dance of electrons,
the forgotten key tometabolism

ID COM:5981
PS2-9
Title: Acupuncture treatmentin the Postoperative period of
Immediate Breast Reconstruction

ID COM:6081
PS2-1
Title: Effects of Chikung On
Non-Hodgkin Lymphoma Survivors
ID COM:5841

ID COM:5982
PS2-10
Title: Reduction of allergic reactions in ears and throat by
the use of natural oils and dietchange – pilot study

PS2-2
Title: Adherence to allopathic
treatment through complementary traditional medicine

ID COM:5987
PS2-11
Title: Acupuncture in the treatment of bruxism and tinnitus
ID COM:5997

ID COM:5953
PS2-3
Title: Quality of life of people
suffering from chronic pain
may be significantly improvedby the use of natural oils anddiet change
ID COM:5958
PS2-4
Title: Head lice at school: Natural products from traditional
medicine and community engagement with theatre andmusic

PS2-12
Title: The use of natural oils
and diet change may help patients in reduction of pain ofdifferent origins – our experience
ID COM:5998
PS2-13
Title: The use of natural oils
and diet change can improve
quality of life in people suffering from allergy – results frompilot study

BOOK OF ABSTRACTS | 12th European Congress of Integrative Medicine · 1st International Symposium on Integrative Health and Education

ID COM:5999
PS2-14
Title: An influence of naturaloils and diet change on the useof antihistamines and decongestants in people sufferingfrom allergy – results from pilot study
ID COM:6009
PS2-15
Title: Describe whether Tai Chi(TC) is effective in preventing
falls in older people
ID COM:6013
PS2-16
Title: Correlating Traditional Chinese Medicine Asthma Phenotypes to Objective Conventional
Medicine Asthma Evaluation
ID COM:6018
PS2-17
Title: Danggui-Shaoyao-San for
Dementia: Systematic Review
ID COM:6128
PS2-18
Title: The presence of food intolerance, bacteria, and toxins insubjects with various diseases
revealed by bioresonance
ID COM:6129
PS2-19Title: Prevalence of bacteria,
toxins, and food intolerance insubjects diagnosed with digestive system ailments revealed bybioresonance
ID COM:6130
PS2-20
Title: The most prevalent healthburdens revealed by bioresonance in patients suffering fromcirculatory diseases - our experience
ID COM:6135
PS2-21
Title: Natural oils and dietchange may help people suffering from allergy – results frompilot study
ID COM:6136
PS2-22
Title: Effects of concomitant

9

use of natural oils and dietchange on some nasal symptoms in people suffering fromallergies – pilot study

Title: Interoceptive Awarenessin Studies of Mind-Body Therapies: a Review of ResearchStudies

ID COM:6157
PS2-23
Title: Hashimoto thyroiditis
consensus document of the
Spanish Society of Health andIntegrati>ve Medicine SESMI:
An integrative vision

ID COM:5911
PS3-4
Title: Association between
metabolic diseases andblood stasis: a survey of Korean medical doctors

ID COM:6158
PS2-24
Title: Naltrexone at low dose
for the treatment of chronicpain

ID COM:5913
PS3-5
Title: Herbal medicines formetabolic diseases withblood stasis: A systematic
review and meta-analysis

ID COM:6159
PS2-25
Title: Chronic urticaria and histaminergic angioedema
ID COM:5967

ID COM:5965
PS3-6
Title: The Effects of Surgery
on Plasma Vitamin C Concentrations and Cognitive
FunctionPS2-26
Title: Osteopathic treatment in
Chronic Musculoskeletal Pain
Diseases – Results of an Observational Pilot StudyID COM:6166
PS2-27
Title: Levels of vitamin D3 inblood and tear of athletes
practicing indoor and outdoor
activities and evaluation of effectiveness of vitamin D3 eye
drops
ID COM:5752
PS3-1
Title: Effects of vegan versus
meat-rich diet on markers ofinflammation – a randomized,
controlled trial
ID COM:5805
PS3-2
Title: Effectiveness of Standardof Care versus Its Combination
with Reflexology, and Sham
Reflexology on Preoperative
Anxiety in Patients Undergoing
Laparoscopic Cholecystectomy:
A Randomized Controlled Trial.
Preliminary Results
ID COM:5851
PS3-3

ID COM:5984
PS3-7
Title: Chronic fatigue syndrome and blood level ofsome hormones
ID COM:5985
PS3-8
Title: Levels of some biochemical parameters insubjects with high bloodpressure
ID COM:5986
PS3-9
Title: Interesting laboratory
findings in female patientswith inability to conceive
ID COM:6019
PS3-10
Title: Cinnamomum camphora ameliorates cognitive
impairment and promotes
neuroprotection in mousemodel of Alzheimer’s disease
ID COM:6052
PS3-11
Title: Effects of two mushroom extracts on symptom
alleviation in osteoarthritis
patients: Pilot Study

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BOOK OF ABSTRACTS | 12th European Congress of Integrative Medicine · 1st International Symposium on Integrative Health and Education

ID COM:6054
PS3-12
Title: Series study of cases
treated with Energy Regulation Therapy ()ID COM:6084
PS3-13
Title: Influence of cocoa drink
product, on acute physicalstress, in sedentary persons
ID COM:6093
PS3-14
Title: Non-invasive brain stimulation in the treatment of chemotherapy-induced neuropathy
ID COM:6138
PS3-15
Title: Effect of acupuncture on
autonomic nervous system of
hemodialysis patients : A randomized, double-blind, placebo-controlled trial
ID COM:6141
PS3-16
Title: A New Discovered Chakra
3.5 “Janika” could be the missing link in the future research
for integrative treatment of
the Metabolic Syndrome
ID COM:6143
PS3-17
Title: Medicinal mushrooms:
A review of scientific evidence
from systematic reviews andmeta-analysis
ID COM:6144
PS3-18
Title: Ketogenic diet for dog
with Brain Tumor
ID COM:6147
PS3-19Title: Association between Living environment and allergic
rhinitis in the Korean adult
population: the Korean National Health and Nutrition Examination Survey 2013-2017

ID COM:6156
PS3-20
Title: Impact of health-related behaviors on Metabolic
Syndrome: using the Korea
National Health and Nutrition
Examination Survey
ID COM:5949
PS3-21
Title: Implications in lower
members of vestibular dysfunction
ID COM:6002
PS3-22
Title: Microbloodletting in MC9
in cases of Arterial Hypertension
ID COM:6011
PS3-23
Title: Acupuncture and Moxibustion treatment for cervicalripening
ID COM:6029
PS3-24
Title: Acupuncture as a treatment in breastfeeding problems
ID COM:6039
PS3-25
Title: A pilot study of standardization in the English translation of traditional Korean medicine prescription terminology
ID COM:6160
PS3-26
Title: Integrative Nursing inclinical practice
ID COM:
PS3-27
Title: Generalized tetanus:
successful outcome when an
integrative approach is incorporated

1st International Symposium on Integrative Healthand Education
Introduction
Round table: Educational experiences in Integrative Health at
the international level
81 Kreitzer MJ
82 Rossi, E
83 Gunnardosttir, TJ
84 Salil, A
Round table: Educational experiences in Integrative Health at
the national level
85 Tinao, JF
86 Rigau, J
87 Fernández-Cervilla, AB
85 Domingo, C
88 Rovira, A
89 Fernández-Fortuny, T
90 Ricomà, R
Key Note
91Shinrin-yoku (forest bathing):
an integrative approach tohealth and well-being
Hansen, M
Workshop
92 The GIM (Guided Imagery
and Music) method: how toactivate the internal health resources of listening to music
Mailahn, C; Aillón Ramos, L

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ABSTRACTS

BOOK OF ABSTRACTS | 12th European Congress of Integrative Medicine · 1st International Symposium on Integrative Health and Education

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BOOK OF ABSTRACTS | 12th European Congress of Integrative Medicine · 1st International Symposium on Integrative Health and Education

OVERALL SITUATION AND FUTURE OF
INTEGRATIVE MEDICINE IN GERMANY
Prof. Dr. Benno Brinkhaus, MD professor of Internak
Medicine and Clinical Epidemiology. Charité University Medicine Berlin, Germany.
Various cross-sectional studies show that more than 60% of the
population in Germany use complementary medicine methods,
above all naturopathy. A large majority of respondents also support
Integrative Medicine, not as an alternative, but as an extension of
conventional medicine. In Germany, more than 50,000 doctors offer
naturopathic and complementary therapies. In addition, alternative
practitioners also offer complementary therapies.
The wish of patients for a change in medicine is still insufficiently taken into account in the German health care system. Althoughcertain complementary therapy methods such as acupuncture,
osteopathy, anthroposophic medicine and homeopathy are partly
financed by the health insurance funds for defined diseases, mosttherapy methods, especially in naturopathy, are not financed. Although there is a growing number of professors in Germany in thefield of naturopathy and integrative medicine, these subjects aretaught only partially and not nationwide and with the same intensity at medical universities in Germany.
In the last two decades, research in the field of naturopathy andcomplementary medicine has increasingly been carried out at German medical universities with constantly improving quality. The
financing of basic and clinical research in the field of naturopathy
and complementary medicine remains problematic, so that thescientific evidence in this area is only slowly growing. Particularly
criticalpopulationgroups,ontheotherhand,aretakingactionnotonlyinEuropebutalsoincreasingly in Germany against complementary
therapies in order to discredit them in a targetedmanner.
Only if Integrative Medicine can be investigated at the highest
quality level, can be evidence-based or at least evidence-informed
and subsequently be implemented, it will be able to withstand theincreasing cost pressure in the health care system and the targeted
hostilities.

CURRENT SITUATION AND RESEARCH IN
INTEGRATIVE MEDICINE IN THE US

approach among those examined in 2017. In recent years, the practice of yoga and meditation has become more mainstream. Most
adults who see a chiropractor have health insurance coverage forthis approach.
The Institute for Healthcare Improvement has advanced
world-wide what is often referred to as the triple aim of health care
– an initiative focused on improving patient care by improving thehealth of populations, enhancing the experience of care for individuals, and reducing the per capita cost of health care. Recently,
a 4th aim has been proposed– care team wellbeing. This reflects
the importance of improving the work life of health care providers,
including clinicians and staff. Another major emphasis in the US is
the promotion of non-pharmacological approaches for pain management. This has taken on heightened urgency given the opioid
addiction epidemic. The Joint Commission that accredits hospitals
now has a requirement that hospitals provide nonpharmacological
pain treatment modalities. Both of these initiatives create a context
for integrative health to grow and flourish.
Within acute care settings, there is a growth in integrative nursing, a strategy aimed at achieving the quadruple aim and improved
symptom management. Integrative nurses bring a whole person
perspective to care at the bedside 24/7. One of the core principles
of integrative nursing is to use a “least intensive/invasive to most”
strategy in addressing symptom management be that pain, anxiety,nausea, fatigue or the myriad of other symptoms patients experience as a result of their disease or treatment. Within clinical settings,
a strong business and clinical case can be made for the use of integrative approaches.
The National Center for Complementary and Integrative Health(NCCIH) is the NIH institute with a primary focus on research funding in integrative health and medicine. Current priorities of theCenter include the following:
Advance fundamental science and methodsdevelopment.
Improve care for hard-to-managesymptoms.
Foster health promotion and diseaseprevention.
Enhance the complementary and integrative health researchworkforce.
Disseminate objective evidence-based information on complementary and integrative healthinterventions.

Mary Jo Kreitzer PhD, RN, FAAN
Integrative approaches continue to be highly utilized in the US.
According to the National Health Interview Survey, the use of yoga,
meditation, and chiropractors among U.S. adults increased from2012 to 2017. Of these, yoga and meditation had the largest percentage-point change.
Women were more likely than men to use yoga, meditation,and chiropractors. Additionally, the use among non-Hispanic white
adults was generally higher than among Hispanic and non- Hispanic
black adults. The pattern of use by age varied for each approach.
Yoga was the most popular approach used in 2012 and 2017, with
9.5% (22.4 million) and 14.3% (35.2 million) adult users, respectively. In 2012, seeing a chiropractor was as popular as yoga, followedby meditation; however, the popularity of meditation surpassed
that of seeing a chiropractor to become the second most-used

INTEGRATIVE MEDICINE: SITUATION IN
ITALYElio Rossi. Homeopathic Clinic of the Hospital Campo di Marte, Lucca (Italy) – Regional center of reference for homeopathy. Coordination center for Complementary Medicine of ASL Tuscany North West
Introduction.
Complementary Medicine (CM) is being increasingly used by European citizens in order to increase their overall state of health andwell-being, as well as to treat various illnesses and diseases. Theinterest for these therapies has progressively risen also in Italy andBOOK OF ABSTRACTS | 12th European Congress of Integrative Medicine · 1st International Symposium on Integrative Health and Educationin Tuscany as well.
Aim.
The aim of this presentation is to describe the pathway and results of the integration process of CM in the public healthcare service in the region of Tuscany (Italy) lasting more than 20 years.
Results
In Italy the reform of Title V of the Italian Constitution allows each
Region to decide how to put into practice and organize the Public
Healthcare System. The agreement among the Italian National Government, the Regions, and the Provinces of Trento and Bolzano on
the terms and requirements for the quality certification of training
and practice of acupuncture, herbal medicine, and homeopathy by
medical doctors and dentists, signed on February 2013, sets up rules for education and training in acupuncture, herbal medicine, homeopathy, homotoxicology, and anthroposophic medicine. Someregions, including Tuscany, have decided to include Complementary
Medicine in their Essential Levels of Assistance, by creating somestructures that integrate the health services into the public structures. Since 1996, the Tuscan Regional Healthcare Plans (RHPs) havebeen considering the role of Complementary Medicine (acupuncture, herbal medicine and homeopathy). The RHP of Tuscany havestarted to incorporate several types of CM treatments (i.e., acupuncture, herbal medicine and homeopathy) in 1996. Furthermore,
the Region of Tuscany decided to include CM in the Essential Levelsof Assistance (ELA) in 2005. Accordingly, a network of 107 publicclinics providing CM health services was built and the relative regulations (i.e., laws, bills, resolutions, etc.) were approved by theregional authorities.
Conclusion
The Italian regulation on education in CM could be a point of reference in the process aimed at defining rules in the European Union.
Moreover, the Tuscan experience has shown the feasibility of CM
integration into the Public Healthcare Service.
References
Rossi E, Di Stefano M, Picchi M, Panozzo MA, Noberasco C, Nurra
L, Baccetti S. Integration of homeopathy and complementary medicine in the Italian and Region of Tuscany public health system, andthe experience of the Homeopathic Clinic of the Lucca Hospital. Homeopathy 2018 May;107(2):90-98. doi:10.1055/s-0038-1636839.
1. Belvedere K, Rossi E, Di Stefano M, Baccetti S. The Process of Integration of Complementary Medicines in Public Healthcare Service of Tuscany (Italy). OBM Integrative and Complementary Medicine
2019;4(2):14; doi:10.21926/obm.icm.1902022.

INTEGRATIVE MEDICINE IN AUSTRALIA:RESEARCH AND EVOLUTION
Professor Avni Sali (Australia)

Integrative Medicine (IM) provides opportunities to expand thelimited boundaries of conventional medicine where the focus is on
diagnosis and drug treatment. IM offers the patient a more wholistic approach to their healthcare which makes use of all scientifically

13

validated therapies, both conventional and complementary.
In westernised countries, there are basically two types of medicine: prescription medicine and integrative medicine. In general there has been lack of government support for Integrative Medicine,which has made it difficult to progress this mainstream medicineof the future.
In the USA the momentum of Integrative Medicine has moved ata more progressive pace. In 2014 the American Board of Physician
Specialties formally recognised ‘Integrative Medicine’ as a medical
specialty, like any other speciality eg. Surgery or Psychiatry.
In Australia, Integrative Medicine Clinics are increasingly now being established, and run primarily by medical practitioners. In the
future all primary care doctors will be expected to have a minimallevel of knowledge about Integrative Medicine.1
The National Institute of Integrative Medicine (NIIM), located in
Melbourne and in another state, is the leading clinical medical Research Centre in Integrative Medicine. We are dedicated to establishing a strong evidence base for effective healthcare treatments
and technologies.
National Institute Complementary Medicine (NICM) in Sydney,
was established to do research in complementary medicine. This isa Government funded initiative. There are also several Universities
who do a small amount of research related to Integrative Medicine.
Naturopathy centres traditionally have been involved predominantly with education, but are now also beginning to do some research.
The major representative bodies in integrative medicine inAustralia are - The Australasian Integrative Medicine Association(AIMA) and The Australasian College of Nutritional and Environmental Medicine (ACNEM). AIMA was set-up to represent Doctors
who practice Integrative Medicine and ACNEM is primarily focusedon education and representation.
1.At NIIM, our vision is to create a medical model for all to experience optimal health and wellbeing through Integrative Medicine.
We envisage that one day all medicine will be ‘Integrative Medicine’.
References
Brophy E, The GP’s Duty of care, J Comp Med, March/Apr 2009pp2024

PRESENT AND FUTURE OF INTEGRATIVEMEDICINE IN JAPANSuzuki, K Vice President of the Japanese society ofintegrative medicine, Chief director of Tokyo Ryo‐In
Clinic. President of the MOA Health Science Foundation (JP)“Japan has its own health problems: population aging, chronic
diseases, dependence on the elderly, as well as the environmental
impact on people’s health. Its geographical situation requires support and prevention programs for natural disasters. Japanese Integrative Medicine works to offer solutions to these problems. Thereis a deep interest on the part of Japanese society. Japan also hasan added knowledge that starts from the tradition in its ancestral
medicine along with the deep knowledge of Western medicine. Integrative Medicine relies on both knowledge. An own contribution
is the social arm of health and integrative medicine”

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BOOK OF ABSTRACTS | 12th European Congress of Integrative Medicine · 1st International Symposium on Integrative Health and Education

INTEGRATIVE MEDICINE IN SPAIN:ADVANCES IN RESEARCH
Pere Gascón, Servei d´Oncología Mèdica Hospital
Clínic, Universitat de Barcelona, Barcelona
The situation of Integrative Medicine in Spain can be seen fromtwo viewpoints. First off,thereisthegrowingacceptanceofintegrativetherapiesamongpatients.Nearly50% of patients already use
some type of these therapies. This fact clashes with the scarce
acceptanceorcompleterejectionofthesetherapiesbythepublichealthadministration and official institutions. We could say that
Integrative Medicine is limited to the private sphere. Curiously,
the current culture concerning ecological and natural elements
has promoted the use of medicinal plants and the growing
appearance of stores dedicated toecologicalandnaturalproducts.
Inresearch,littleprogresshasbeenmade.APubMed review of thelast five years shows limited productivity in areas of prevention, inflammation and obesity. There are currently clinical trials
on the effect of fungal extracts on metabolic syndrome and on
peripheral neuropathy. The lack of funding representstheprimarybarrierinordertocarryoutstudieswithinthefieldofintegrative
medicine.ThecurrentsituationofSpanishinstitutionsdoesnotallowustobeoptimistic about the future of research in this field inourcountry.

ENVIRONMENTAL ONCOLOGY:
EXPANDING THE VIEWPOINTS ON
CANCER PREVENTION AND TREATMENT.
Natàlia Eres. Especialista en Oncología Médica.
Experta en Medicina y Oncología Integrativa.
Directora Médica de imohe (Instituto de Salud,
Medicina y Oncología Holística). Codirectora deOnco-Heat Barcelona (Unidad de Hipertermia Oncológica adyuvante) Consultora de la plataforma
divulgativa de oncología integrativa de Medsyr(Medica Scientia InnovationResearch).
The most recent statistics from the IARC (International Agency
for Research on Cancer), GLOBOCAN 2018, reveal 18.1 million
new cases of cancer worldwide (4 million more than in 2012),
with 9.6 million cancer-related deaths.
The advances in our understanding of the molecular bases involved in carcinogenesis confirm that most alterations that contribute to cancer are not inherited, but rather are attributed tosomatic mutations and epigenetic changes due to environmental
factors. At the epidemiological level, a review carried out in 2014
estimated that 42% of all cancers from America were attributable to risk factors, all of which were potentially avoidable withprevention strategies. What about the other 58%? We currently
have a great deal of scientific evidence that directly links cancer
to environmental and occupational exposure.

If the current regulation and education policies have not managed to control the impact of lifestyle- associated carcinogens,with regard to controlling environmental and occupational exposure, we are even further away at all levels: legislative reforms toremove regulatory barriers, implementing local policies to eliminate known toxins, recognition of carcinogens that have not yet
been accepted, application of key concepts such as the delayed
impact of early exposures and the lack of a threshold due to accumulated long-duration exposures at multiple doses.
But what is even more serious; although it may seem paradoxical, cancer therapy - from the environmental health perspective- poses important ethical issues: the same treatments that areused to fight cancer are done through a mechanism of action thatis intrinsically carcinogenic, both directly (in terms of genotoxicity, that is in the induction of mutations) and indirectly (in termsof hormonal disruption effects, cytotoxicity, epigenetic changes,
inflammation, immuno-disruption), for the rest of the cells of the
body. There are studies which confirm the genotoxic capacity ofchemotherapy and ionizing radiation, but also hormonal modulators such as tamoxifen and biological therapies. We also cannot
overlook the ecotoxic capacity of the metabolites of these drugs.
Along these lines, the European Economic Community set up the
CytoThreat (www.cytothreat.eu) project in 2011, focused on evaluating the impact of cytostatic drug residue on the environment
and the risks for human beings, reaching the conclusion that they
are highly dangerous products which require a multidisciplinary
action plan.
Speaking of environmental oncology, I would therefore propose highly ambitious, non-immediate goals that would involve theneed to create interdisciplinary sectors linked to academic andresearch institutions. In the meanwhile, in the clinical field, there
is sufficient scientific literatureand experience to put recommendations and treatments inplace to help at least neutralise the toxic and carcinogenic effects
on the body. Both the therapeutic focus of environmental medicine as well as plant-based epigenetic modulation, pharmacogenetics and pharmacogenomics must serve as inspiration until wereach more intelligent therapies and more responsible policies.
• Freddie Bray, BSc, MSc, PhD et al. Global Cancer Statistics 2018:
GLOBOCAN Estimates of Incidence and Mortality Worldwide for 36
Cancers in 185 Countries . CA CANCER J CLIN 2018;68:394–424• Farhad Islam , Ann Goding Sauer et al. Proportion and Number ofCancer Cases and Deaths Attributable to Potentially Modifiable Risk
Factors in the United States• CA CANCER J CLIN 2018;68:31–54• Thun MJ, Wild CP, Colditz G. Framework for understanding cancer
prevention. In: Thun MJ, Linet MS, Cerhan JR, Haiman CA, Schottenfeld D, eds. Cancer Epidemiology and Prevention. 4th ed. New York:
Oxford University Press; 2018:1193-1204.
• Harris CC. The carcinogenicity of anticancer drugs: a hazard inman. Cancer. 1976:1014- 23.
• Takehiko Nohmi . Thresholds of Genotoxic and Non-Genotoxic
Carcinogens. Toxicol. Res.
2018. 281-290• Priya A, Toolaram K, et al. Environmental risk assessment of anti-cancer drugs and their transformation products: A focus on their

BOOK OF ABSTRACTS | 12th European Congress of Integrative Medicine · 1st International Symposium on Integrative Health and Education

genotoxicity characterization-state of knowledge and short comings.
Mutation Research/Reviews in Mutation Research, 2014: 18-35• Daniel W, NeBert A, et al. Human Drug-Metabolizing Enzyme Polymorphisms: Effects on Risk of Toxicity and Cancer . DNA and cell biol.
1996: 273-280• https://www.cancer.org/cancer/cancer-causes/general-info/
known-and-probable-human- carcinogens.html• Hong-Bae Kim, Jae-Yong Shim et al. Long-Term Exposure to Air Pollutants and Cancer Mortality: A Meta-Analysis of Cohort Studies. Int J
Environ Res Public Health. 2018 Nov; 15(11): 2608.
• Smith RE, Bryant J, et al. National Surgical Adjuvant Breast andBowel Project Experience. Acute myeloid leukemia and myelodysplastic syndrome after doxorubicin- cyclophosphamide adjuvant therapy
for operable breast cancer: the National Surgical Adjuvant Breast andBowel Project Experience. J Clin Oncol. 2003;21(7):1195–204.

DO YOU LIVE IN A HEALTHY PLACE?
Pere León. Architect and geobiologist
International organizations such as IARC (International Agency for Research onCancer),orWHO(WorldHealthOrganization)
amongothers,recognizethe influence and adverse effects of theenviromental electric and magnetic fields on ourhealth.
There are currently numerous worldwide scientific studies that
confirm the correlation between increase in immune diseases
and different types of cancers, and the global electromagnetic
spectrum.
As an expert in biohabitability and geobiology, I have observedin more than 3,500 environmental analysis carried out, a significant and troubling raising incidence of electrosensitivity caseswith an annual growth of 5%.
We live surrounded by an growing level of electromagnetic radiation and this hasanegativeimpactonourhealth,relatedtotheincreaseincasesofcurrent diseases.
We know that when we sleep, all the biological processes ofcell repair take place. To guarantee a restful sleep, it’s necessary
not to be exposed to electromagnetic fields affecting especiallypineal gland, the organ in the brain that produces the hormone
melatonin, a substance that helps control our sleeping and waking cycle.
My conclusion, based on my experience, is that we must sleepin spaces withoutelectromagneticfieldsandpollutiontoavoiddiseasesandthuswelive more healthylives.

ENVIRONMENTAL TOXINS AS A
TRIGGER FOR MULTIPLE PATHOLOGIES.
Dr. Pilar Muñoz-Calero Peregrin
Summary:
The environment is one of the determinants of the state ofhealth of the population. Environmental pathologies are a set of
disorders caused by exposure to chemical and physical productsin the environment. In industrialised countries it is estimatedthat 20% of the incidence of all diseases can be attributed to en-

15

vironmental factors.
The xenobiotics present in the environment can be inhaled oringested involuntarily. Heavy metal contamination present in theair, water and food is another very frequent source of contamination to which the human being is exposed and contributes to thealteration of homeostasis, in various aspects of metabolism andthe toxicity of macrophages.
Xenobiotics have a tendency to deposit in the central and peripheral lymphoid organs, hindering an adequate immune response to infections. In the presence of environmental pollutants,
they can act as cofactors of acute or chronic infectious diseases.
The enzymatic activity of cytochrome P450 is frequently altered, making it difficult to treat these pathologies. It is also common to see a genetic polymorphism caused by environmental
pollution generating immunological, carcinogenic or allergic pathologies.
In this presentation we will emphasise the impact of environmental pollution on patients with environmental pathologies
with associated chronic infections and chronic immunosuppression. We will also explain our experience with the treatment ofsome real cases.

HEALTHY AND URBANITYAIR QUALITY AND HEALTH IN THE CITY:
THE LANDSCAPE AS INFRASTRUCTURE
Marc Chalamanch - Miquel Lacasta - Carmen Santana Luis Antúnez 6 - 08006 Barcelona - info@
archikubik.com - www.archikubik.com
INTRODUCTION
The industrial civilisation has reached a new level of consumption. According to many scientists, the massive productionof garbage and detritus lied to mega consumption and humanactivities has such a huge impact on geological forces that the
behaviour of the planet has changed definitively. Our footprint
on the environment is so present that impacts are already being
experienced day after day: global warming, extinction of certain
species, acidification of the oceans, etc. We are entering on theera of the Anthropocene.
On a social level, our civilisation’s solidarity and fairness arelimited, forgetting millions of individuals, particularly those who
are the most in need: children, elderly people, sick and handicapped citizens, or rather, those who are not or no longer productive.
Far from being unavoidable, those impacts are determinedby political, economic and ideological choices decided by a verysmall selection of powerful corporations or individuals.
How can Humanity take a hold of its own destiny?
The architecture that makes our cities is what plays a definingrole in answering this question. We are convinced that creatinga healthy city starts with the creation of one that is humanised.
HUMANISING OUR CITIESOn one hand, we firmly believe that the catalyst for change will
be fuelled by the education of the residents.
By implementing education everywhere and not only in

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BOOK OF ABSTRACTS | 12th European Congress of Integrative Medicine · 1st International Symposium on Integrative Health and Education

schools and universities. Educating from our cities, from publicand domestic spaces as well as those related to production andwork environment.
All the while, we must help citizens become aware, thanks tothe evolution of technology, of we are all key actors in the production and emission of information.
For the first time in history, we, all concerned as inhabitantson this earth, have the possibility to take power and inverse theorder of pre-established processes. Each one, from the youngest
to the eldest, must be aware of our actions and their consequences as we are no longer isolated. The way in which we consume,in which we treat one-another (be it friend or stranger) and inwhich we respect together the fundamental values of Mother
Nature and those of real democracy.
It’s our duty, now more than ever, as Urbanists and Architects,
to HUMANISE OUR CITIES, so as to educate the inhabitant´smannerisms to become more inclusive and respectful, in orderto make diversity and tolerance become values in each and every
one of us, so we were able to face head on the changes of theparadigm of our world in transition.
On the other hand, the era of political ethics has arrived. We
don´t have time to spare. We need a truly engaged political class
who make this historical transition a priority.

HUMAN EXPOSURE TO ENDOCRINEDISRUPTORS AN HEALTHCONSEQUENCES
Nicolás Olea. Universidad de Granada/Hospital
Clínico S. Cecilio Instituto de Investigación Biosanitaria ibs.GRANADA Granada
Resumen
Human exposure to environmental toxic compounds of very
different origin is a well-known and well-documented fact. Despite this, the association between exposure and health effecthas not always been established with the depth we believe
is necessary. In fact, in the last two decades new data haveappeared in specialized scientific literature linking exposure
to certain chemical compounds, introduced into the environment by human activity, to the emergence of new syndromes
and development of specific diseases, of cause not well known,
but involving an alteration of hormonal balance, phenomenon
identified as endocrine disruption. Concern about the increasing incidence of this type of alterations has attracted the attention of clinicians and researchers trying to formulate, withgreater or less success, new conceptual approaches in the etiology of the disease and endocrine disruption. Endocrine disruptors are found in a wide variety of products such as pesticides,
industrial chemicals, utensil and commonly used components,
cosmetics and textiles , which have been introduced into theenvironment by human activity and relate to consumption habits. The EU has established regulations on the use of pesticides
and consumer objects that should ensure the protection of theenvironment, human and animal health. Despite this, there arestill some doubts about the effectiveness of these measures asaspects such as the toxicological assessment of endocrine disruptors is not routine in the process of authorizing pesticides
and consumer products, which poses a risk important consumer exposure to conventionally produced agricultural products
or through the consumption of objects such as plastics, detergents, cosmetics or textiles.

PHARMACOGENETICS: THE ROAD TOPERSONALIZED THERAPY
Juan Sabater Tobella. Member of the Pharmacogenomics Research Network President of Eugenomic®.
The therapeutic guidelines, in most centers, are based on the protocols developed by their expert committees. With adjustments forage, weight, sex and renal function, they apply to patients with thepathology for which has been developed the protocol. That is to say“one size fits all”. But one size not fit all. We are genetically different
and therefore, the protocol will have to have decision algorithms toadapt the drugs to the genetics of each patient.
Approximately 70% of the drugs are metabolized by liver enzymes,
in order to facilitate their subsequent elimination mainly by the renalroute. To reach the therapeutic target they will have to pass throughcell membranes, often by means of transmembrane transport proteins, and finally exert their pharmacological action on the therapeutictarget. Enzymes, transport proteins and therapeutic targets are proteins, and their structure depends on their respective gene. If this genehas some genetic polymorphisms, they can modify the protein activity and function.
Therefore, the same drug, at the same dose, depending on thepatient’s polymorphisms may have the expected pharmacologicalaction, or less effect (therapeutic failure) or more effect (toxicity) depending on the genetics of each patient.
Pharmacogenetics, aims to facilitate the implementation of a personalized therapy for each patient based on their genetic polymorphisms.
Currently, for hundreds of drugs, the FDA and the EMA in their technical data sheets already require the incorporation of pharmacogenetics criteria. Therapeutic guidelines are also developed (ClinicalPharmacogenetics Implementation Consortium Guidelines).
In the presentations, the numbers of deaths due to adverse drug
reactions are presented, and the g‐Nomic® , a pharmacogenetic interpretation software for personalized therapy is presented.

ACUPOINT TRANSCUTANEOUS
ELECTRICAL NERVE STIMULATION IN
HOSPITALIZED COPD PATIENTS WITH
SEVERE DYSPNOEA: PROTOCOL FOR
A MULTICENTRIC DOUBLE‐BLINDEDRANDOMIZED CONTROL TRIAL.
Carles Fernández‐Jané 1,3, Jordi Vilaró 2,3
Affiliations: 1School of Health Science Blanquerna,Ramon Llull University, Barcelona, Spain. carlesfj@

BOOK OF ABSTRACTS | 12th European Congress of Integrative Medicine · 1st International Symposium on Integrative Health and Education

blanquerna.url.edu.
2School of Health Science Blanquerna, Ramon Llull
University, Barcelona, Spain. jordivc@blanquerna.
url.edu.
3Global Research on Wellbeing (GRoW) ResearchGroup, Ramon Llull University, Barcelona, Spain.
Corresponding author: Carles Fernández‐Jané MSc
School of Health Science Blanquerna, Ramón Llull
University Padilla 326‐332

ABSTRACT:
Background: Acute exacerbation of chronic obstructive pulmonary
disease (AECOPD) is a major cause of hospital admissions and dyspnoea is its main symptom. Some studies have concluded that a newmodality of acupuncture called Acupuncture transcutaneous nerve
stimulation (acuTENS) could reduce dyspnoea in COPD patients byincreasing beta‐endorphin levels, however those trials have mainly
been conducted on patients with stable condition. This study aims todeterminate if the administration of acuTENS can reduce dyspnoea inpatients hospitalized for AECOPD.
Methods: A multicentric randomised control trial with patient‐ andassessor‐blinded will be conducted. A sample of 60 patients will berandomised to receive 45 minutes of either real acuTENS or shamacuTENS treatment once a day during 5 consecutive days. The trial
will be conducted at the “Hospital del Mar” of Barcelona (Spain) andthe “Hospital Sant Joan de Déu de Manresa” in Manresa (Spain). The
Borg scale at baseline, and day 1 to 5 will be the primary outcome.
Secondary outcomes will be the duration of the hospitalization, quantity of drugs administrated, expiratory peck flow adverse effects andmortality and readmissions at 3 months.
Discussion: AcuTENS is non‐pharmacological, non‐invasive and cheap intervention. This trial will help to understand acuTENS potential
role in the treatment of AECOPD.

AROMATHERAPY: WELLBEING ON
LABOUR
Author: Cintia La Rosa Muñoz, Midwife at Hospital Del Vendrell, Tarragona
Words: Aromatherapy, Essential oils, Midwifery
practice, oxitocyn release, mood behavior.
Introduction:
The use of aromatherapy in the delivery room is overwhelmed byscientific evidence for its enormous emotional benefits. These results
encourage the team of midwives at the Hospital del Vendrell to expand its use in other stages of women’s care, such as pregnancy andmenopause. During the literature search, not only do we find benefits
at an emotional level, but a wide range of uses for the hormonal mimetic effects of essential oils that are so important in labour.
Objectives
To determine properties, recommendations, safety doses of each oils.
To introduce a new range of oils that are appropriate, safe and beneficial for the progress oflabour
Secundary objectives:
To promote the use of aromatherapy among midwives as another17

tool to implement on the care of women inlabour.
To expand the use of aromatherapy in women health care programs, such as pregnancy andmenopause.
Encourage midwives to take part on research in order to obtain further Evidence based that supports the use of essential oils during theprocess oflabour
Methodology
We reviewed scientific articles in Spanish and English using databases such as Medline, Pub med and Cochrane.
Furthermore we found a wide range of Aromatherapy authors that
already advise the use of essential oils during this period of women
lives. However, only one of them was a midwife. On the other hand,recommendations were found described by official bodies such as
EMA, Commission E, IFRA, GRAS status recognitions, the council ofEurope, EFSA.
Results
The results of our research give us safe recommendations for theuse of essential oils during labour which shall allow us to improve ourprotocols and guidelines.
On the other hand it has been observed that the lack of studies isalso evident and more research is required.
Conclusions:
The initiative of this review not also arise the need to encourage
midwives to participate in research that may be more conclusive dueto the emotional and hormone like attitude of the essential oils, butalso reinforce the use of natural remedies as first lines of health careprograms in physiological processes, Such as labour, pregnancy andmenopause, prior to use conventional medicine.

Bibliography
Effect of aromatherapy on symptoms of dysmenorrhea in college students: A randomized placebo-controlled clinical trial. [citado 7 February2019]. Disponible en:https://www.ncbi.nlm.nih.gov/pubmed/?term=clary+sage+essential+oil+menses
Sidlo (2018). Aromatherpay for menopause succes. 100 essential oil recipes to reclaim your vibrancy. Amazon fulfillment.Poland
Effect of aromatherapy massage on pain in primary dysmenorrhea: A
meta-analysis. [citado 19 February 2019]. Disponible en: https://www.ncbi.
nlm.nih.gov/pubmed/28438280
BALANCE OUT YOUR HORMONES NATURALLY [citado 7 marzo
2019].
Disponible
en:http://www.oilswithsharelle.com/
uploads/9/7/3/6/97361762/balance_out_your_hormones_naturally.
pdf
Changes in 5-hydroxytryptamine and cortisol plasma levels in menopausal women after inhalation of clary sage oil. [citado 715 February 2019].
Disponible en:https://www.ncbi.nlm.nih.gov/pubmed/24802524
Changes in salivary oxytocin after inhalation of clary sage essential
oil scent in term- pregnant women: a feasibility pilot study . [citado 7
marzo 2019]. Disponible en:https://www.ncbi.nlm.nih.gov/pmc/articles/
PMC5721455/
LOUANN BRIZENDINE (2010). El cerebro femenino .RBA bolsillo. 8.
Perimenopausia: Qué es y cómo sé que ha empezado . [citado 13 marzo2 019]. Disponible en: http://www.flaviamenopausia.com/perimenopausia-que-es-como-se-que-ha-empezado
Aceite esencial de Mirto: Normaliza la función de la tiroides y los ovarios. [citado 13 marzo2 019]. Disponible en:https://argentinasinvacunas.
wordpress.com/2014/07/16/aceite-esencial-de-mirto- normaliza-la-funcion-de-la-tiroides-y-los-ovarios/

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Lavender Oil-Potent Anxiolytic Properties via Modulating Voltage
Dependent Calcium Channels [citado 17 marzo2 019]. Disponibleen:://www.ncbi.nlm.nih.gov/pmc/articles/PMC3639265/ (on line enero 2019)
A multi-center, double-blind, randomised study of the Lavender oil
preparation Silexan in comparison to Lorazepam for generalized anxiety disorder. https://www.ncbi.nlm.nih.gov/pubmed/19962288
Lavandula angustifolia Essential Oil and Linalool Counteract Social
Aversion Induced by Social Defeat . [citado 13 marzo 2 019]. Disponible en: https://www.mdpi.com/1420-3049/23/10/2694/htm
Sedative effect of central administration ofCoriandrum sativum
essential oil and its major component linalool in neonatal chicks. . [citado 17 marzo 2 019]. Disponible en:https://www.tandfonline.com/
doi/full/10.3109/13880209.2015.1137602
Effects of Aromatherapy on Stress Responses, AutonomicNervous System Activity and Blood Pressure in the Patients Undergoing
Coronary Angiography: A Non-Randomized Controlled Trial. [citado 126 febrero 2019]. Disponible en:https://www.jkan.or.kr/DOIx.
php?id=10.4040/jkan.2018.48.1.1
Effectsofessentialoilexposureonsalivaryestrogenconcentrationinperimenopausal women. [citado 13 enero 2019]. Disponible en:https://www.ncbi.nlm.nih.gov/pubmed/28326753
Comparison of the effect of lavender and bitter orange on anxiety
inpostmenopausal women: A triple-blind, randomized, controlled clinical trial. [citado 13 marzo 2 019]. Disponible en:https://www.ncbi.
nlm.nih.gov/pubmed/29705445
Effects of Inhalation of Essential Oil of Citrus aurantium L. var. amara on Menopausal Symptoms, Stress, and Estrogen in Postmenopausal
Women: A Randomized Controlled Trial. [citado 2 marzo2 019]. Disponible en: https://www.hindawi.com/journals/ecam/2014/796518/
Comparison of the effect of lavender and bitter orange on sleep quality in postmenopausal women: A triple-blind, randomized, controlled
clinical trial. [citado 10 marzo2 019]. Disponible en: https://www.ncbi.
nlm.nih.gov/pubmed/28749734
Eidanez Gayeski M, Brüggemann OM. Métodos não farmacológicos para alívio da dor no trabalho de parto: uma revisão sistemática.
Index-f.com [Internet].2010 [citado 12 Septiembre 2018];19(4):77482.Disponible en:http://www.index- f.com/textocontexto/2010pdf/19-774.pdf
Borges Osório SM , da Silva Júnior LG, Oliveira Nicolau AI. Evaluación de la efectividad de métodos no farmacológicos en el aliviodel dolor del parto.Redalyc.org [Internet]. 2018 [citado 12 September 2018];15(1):174-184. Disponible en:http://www.redalyc.org/
pdf/3240/324030684022.pd
BurnsE.E,BlameyC,Lloyd,AJ.Aromatherapyinchildbirth:Aneffectiveapproachto care. researchgate [Internet]. 2018 [citado 3 Junio2018];8(10). Disponible en:https://www.researchgate.net/publication/272450347/download
Smith C, Colins C, Crowther C, Lewett TK. Aromaterapia parael tratamiento deldolor durante el trabajo de parto . cochrane library [Internet]. 2011 [citado 3 June 2018];issu7, art º: CD009215.
DO110.1002/14651858.CD009215.Disponible
en:https://www.cochranelibrary.com/cdsr/doi/10.1002/14651858.CD009215/fullTisserand R, Young R. Essential oils safety. Second edition. CHUR-

tría. Manual para el profesional sanitario. Fitoaula;2013.
Burns E, Blamey C, Ersser S, Lloyd A. An investigation into the use ofaromatherapyin intrapartum midwifery practice. Journal of Complementary Medicine. 2000; Medicine.6:141-147.
Burns E, Zobbi V, Panzeri D,Oskrochi R, Regalia A. Aromatherapy inchildbirth: a pilot randomised controlled trial [Internet]. 2007 [citado
14 May 2018];114(7):838-844. Disponible en:https://obgyn.onlinelibrary.wiley.com/doi/epdf/10.1111/j.1471- 0528.2007.01381.x
TISSERAND R. Infographics - Tisserand Institute [Internet]. Tisserand Institute. 2018 [citado 7 February 2018]. Disponible en:http://
tisserandinstitute.org/infographics/
Rashidi-Fakari F, Tabatabaeichehr M, Mortazavi H. The effect of
aromatherapy by essential oil of orange on anxiety during labor: arandomized clinical trial. Iranian Journal of Nursing and Midwifery Research. NCBI [internet] 2015[citado 07 agosto 2018]. Nov-dec ;(20):661-664. disponible en:https://www.ncbi.nlm.nih.gov/pmc/articles/
PMC4700683/
Standards library - IFRA International Fragrance Association - inevery sense.Ifraorg.org [Internet]. 2018 [citado 5 May 2018]. Disponible en:http://www.ifraorg.org/en-us/standards-library/open/23615#.
W5_NdhHtamw

CHILL LIVINGSTONE, ElSEVIER;2014.
Festy D.MI BIBLIA DE LOS ACEITES ESENCIALES, GUIA COMPLETA DE
AROMATERAPIA. Edición española.MEDICI;2016
Young G. Essential oils pocket reference. Seventh edition. LIFESCIENCE productsand publishing;2016
Baulies RG, Torres CR. Fitoterapia y plantas medicinales en pedia-

tor_2914828.html. [citado 3 marzo 2019].
https://blog.nutritienda.com/propiedades-de-los-aceites-esenciales-en-aromaterapia/-[citado 9 marzo 2019].
https://relieved.co/foot-reflexology-baby/. [citado 9 marzo 2019].
https://mx.depositphotos.com/149697098/stock-illustration-woman-lying-on-back-while.html. [citado 10 marzo 2019].

Photography
https://w w w.istockphoto.com/es/vector/car%C3%A1cter-de-una-mujer-y-hombre-en-diferentes-edades-un-beb%C3%A9-un-ni%C3%B1o-un-adolescente-gm984803556-267222752.
[citado 15 enero 2019].
https://www.pinterest.ch/pin/413275703286119074/. . [citado 17
enero 2019].
http://cazadordementes.tumblr.com/post/156695978784/partos-aztecas-en-la-din%C3%A1mica-familiar[citado 17 febrero 2019].
http://osteopatiamaternoinfantil.com/equipo/[citado 17 febrero2019].
https://enfermeraamatrona.blogspot.com/2016/11/curso-fitoterapia-y-plantas-medicinales.html. [citado 18 febrero 2019].
https://www.womenalia.com/blogs/mujeres-despiertas/haz-pesas-y-fortalece-tus-huesos-en-la-menopausia. [citado 16 febrero2019].
https://es.123rf.com/photo_37255723_ilustraci%C3%B3n-de-unachica-que-huele-una-botella-de-aceite-esencial.html. [citado 13 marzo 2019].
http://hddfhm.com/clip-art/clipart-woman-pulling-her-hair-out.
html. [citado 11 marzo 2019].
http://enfermeraamatrona.blogspot.com/2017/02/curso-terapia-neural.html. [citado 17
marzo 2019].
https://www.boiron.es/listado-noticias/noticias/1000757015101/
papel-matronas-homeopatia.1.html.
.
https://www.rcm.org.uk/aromatherapy-in-midwifery-practice.
[citado 17 febrero2019]. http://www.medical-acupuncture.co.uk/.
[citado 18 febero 2019].
https://ellayelabanico.com/y-despues-de-la-menopausia-que/. [citado 1 enero 2019].
https://es.pngtree.com/freepng/cute-child-pound-illustra-

BOOK OF ABSTRACTS | 12th European Congress of Integrative Medicine · 1st International Symposium on Integrative Health and Education

https://it.dreamstime.com/illustrazione-di-stock-dietista-image52186285. [citado 14 marzo 2019].
https://www.gettyimages.es/ilustraciones/comadrona?sort=mostpopular&mediatype=illustration&phrase=comadrona. [citado 14
marzo 2019].
https://pngtree.com/freepng/pregnant-women-queue-to-see-thehemorrhoids_356262.html. [citado 14 marzo2019].
https://www.amazon.co.uk/High-Dwarves-Menopause-Fridge-Magnet/dp/B01E1NMXQK[citado 15 marzo2019].
https://br.depositphotos.com/13955635/stock-photo-anatomy-of-brain-thalamus-l.html. [citado 15 marzo 2019].
https://www.swakeleysmassage.co.uk/maternity-reflexology-training-hillingdon-hospital-midwivesstudent-midwives/. [citado 15 marzo 2019].
https://tisserandinstitute.org/how-essential-oils-work-in-thebody/. [citado 17 marzo 2019].
. [citado 17 marzo 2019].
https://www.amazon.es/Aromatherapy-Midwifery-Practice-Denise-Tiran/dp/1848192886.[citado 17 marzo 2019].

CULTIVATING WELLBEING IN OUR LIVES
AND ORGANIZATIONSMary Jo Kreitzer PhD, RN, FAAN
Stress and burnout of health care providers is a major publichealth issue. Clinician burnout is linked with decreased qualityof care and increased medical errors, decreased patient satisfaction, and reduced productivity and professional effort. Stress andburnout also impacts the wellbeing of the workforce resulting
in increased broken relationships, increased alcohol and substance abuse, depression, anxiety, increased risk of suicide and earlyexit from theprofession.
Healthcare professional “wellbeing” or “care of the caregiver”
is a topic that has not been significantly addressed in the education of healthcare professionals. In fact, the culture that has dominated much of education has been one where students havebeen expected to forego personal needs, endure stressful environments, and emerge from highly competitive and often dysfunctional environments to work in care settings where healthand wellbeing is also largely ignored.
Strategies to address health care provider wellbeing need tofocus on system issues that generate stress and burnout andapproaches that will enhance the wellbeing and resilience of health care providers. Wellbeing leaders:
Understand the value of their own wellbeing, the wellbeing ofothers, and the impact this has on theorganization.
Develop and maintain wellbeing practices and leadership skillsin the face of complexity and challenge.
Recognize and work with patterns at a whole person and whole systemslevel.
Evoke innovative thinking and allow answers to emerge fromdiverseperspectives.
Take adaptive action that transforms individuals, teams, theorganization and the larger community and leads to sustainable
practices andresults.
Energize positive change by making wellbeingcontagious!

19

In short, wellbeing leaders have the capacity to create culturesof wellbeing within organizations.
The Wellbeing Model developed at the University of Minnesota Center for Spirituality & Healing includes 6 determinants
known to impact personal and organizational wellbeing: health,purpose, relationships, community, the environment and safety
and security. For more information, see: https://www.takingcharge.csh.umn.edu/

COST AND HEALTH BENEFITS FROMINTEGRATING NEW AGE AYURVEDA
INTO U.S. AND EUROPEAN HEALTHSYSTEMS (BY EXAMPLE OF THE
METABOLIC SYNDROME)
Dr. Harsha Gramminger MD, Germany
President and Clinic Director, Euroved GmbH, Germany & Vice-President of European Ayurveda Association
General Health Costs are spiraling in all developed and developing
nations of the world. In 2013, Germany spent almost € 315 billion on
health.
This was an increase of about € 12,1 billion compared to 2012 :
3910,00 € in 2013 vs. 3770,00 € in 2012 per inhabitant.
Type 2 Diabetes, Obesity, Hyperlipidemia, Hypertension & Other“civilization” diseases are the main factors for these costs.
With over 8 million sufferers (in 2009 and growing), Diabetes Mellitus is one of the most widespread diseases in Germany.
Serious “secondary complications” and “associated diseases” /co-morbidities include heart attack, stroke, athlete’s foot etc.
Total costs € 3.817.00 includes three components: Direct - disease(), Indirect () & associated complication ()Obesity is another new global epidemic and set to become the“number one health problem globally” by the year2025. In 2013 52%of all Germans were overweight, which is about
Million people! The associated conditions include: Type 2 Diabetes,
Hypertension, Vascular diseases, Stroke, Coronary heart disease, Gallstones, Cancer, Sleep Apnea Syndrome, Diseases of the joints and of
the skin andmore.
Clinical and practical experience is proven, that Ayurveda is able
to improve the condition of both Type 2 diabetes and Obesity. Furthermore, it is able by its lifestyle guidance and preventive holistic
approach,to reduce and avoid follow – up diseases and costs.
The presentation will show with facts and figures how the wisdomof Ayurveda can be followed for the New Age to prevent, manage andcure such diseases.
Figures for savings to the European and U.S. Health care costs will
be presented and discussed.
The presentation will show with facts and figures how the wisdomof Ayurveda can be followed for the New Age to prevent, manage andcure such diseases.
Figures for savings to the European and U.S. Health care costs will
be presented and discussed.

20

BOOK OF ABSTRACTS | 12th European Congress of Integrative Medicine · 1st International Symposium on Integrative Health and Education

VITAMIN C AND CANCER: TOWARDS ANINTEGRATIVE PATHWAY OF MOLECULARRESEARCH AND CLINICAL PRACTICE
ÓSCAR AGUILERA
Translational Oncology Unit of the Jiménez Díaz
Foundation, Madrid (SP)KRAS mutation is often present in many hard-to-treat tumors suchas colon and pancreatic cancer and it is tightly linked to serious alterations in the normal cell metabolism and clinical resistance to chemotherapy.
In1931,thewinneroftheNobelPrizeinMedicine,OttoWarburg,statedthat cancer was primarily caused by altered metabolism interferingwith energy processinginthenormalcell.Increasedcellglycolyticrateseveninthepresence of oxygen is fully recognized as a hallmark in cancer
and known as the Warburg effect.
In the late 1970’s, Linus Pauling and Ewan Cameron reported thatvitamin C may have positive effects in cancer treatment, althoughdeep mechanistic knowledge about this activity is still scarce.
We describe a novel antitumoral mechanism of vitamin C in KRAS
mutant colorectal cancer that involves the Warburg metabolic disruption through functional alteration of key metabolic checkpoints in
KRAS mutant cancer cells. Vitamin C modules the expression of the citric acid cycle (CAC) inhibitor, Pyruvate dehydrogenase kinase-1 (PDK1) through downregulation of the Hypoxia Inducible Factor (HIF-1).

INTEGRATIVE MEDICINE IN
ONCOLOGICAL PATIENTS IN A SPANISH
PUBLIC HOSPITAL
Abadía Castelló Cristina1, Garriga Mora Salut 2,
León Pizarro Concha 2, García Alonso Dolors2,
Gispert Anna 2, Arcusa Lanza Angels3, Dalmau
Santamaria Ishar 2,4, Departments of 1Integrative
Health Unit Coordinator 2Integrative Health Unit,
3 Head of Oncology Department,Consorci Sanitaride Terrassa, 4Gimbernat and Tomas Cerda University Colleges –UAB. Barcelona, Spain
The use of associated oncospecific treatments with complementary therapies (CT) is well known and highly relevant in terms of theirsocial and medical significance. This study aims to determine if in ourenvironment the use of CT improves quality of live and anxiety or depression levels in cancer patients.
Concurrently offered to outpatients in the course of adjuvant chemotherapy or within six months after this, CT delivered simultaneously with the standard treatment for side effects were: mindfulness,
biofield therapies, acupuncture and nutritional support, based on aclinical interview by a medical member of our integrative health unit.
Patients signed an informed consent and completed the HAD (anxiety and depression) and QLQC-30 questionnaires at the beginning andend of the intervention.
Between May 2016 and April 2017, 52 patients participated in the

study, 63% receiving nutritional advice, 54% acupuncture, 65% biofield therapies, and 12% mindfulness training. Pre- and post- intervention evaluations found statistically significant reductions in the levelsof anxiety (HAD- A: p=0,002) and depression (HAD-D: p=0,04). Qualityof life improved significantly in global (p=0,02) and emotional (p = 0,01) dimensions. A reduction in symptoms such as pain, nausea, andfatigue were noted, as well as an improvement in appetite. Patientsatisfaction was 100%.
The use of CT improved the quality of life, anxiety, and depression
in patients with cancer, a finding in line with other reported findings.

Reference:
Evidence-BasedClinicalPracticeGuidelinesforIntegrativeOncology:ComplementaryTherapiesand Botanicals. Journal of the Society for Integrative
Oncology, Vol 7, No 3 (Summer), 2009: pp85–120
J Clin Oncol 36. © 2018 by American Society of ClinicalOncology
Post-Whiteetal.TherapeuticMassageandHealingTouchImproveSymtomsinCancer.Integrative Cancer Therapies 2(4); 2003 pp.332-344
Improve Symptoms in Cancer. Integrative Cancer Therapies 2(4); 2003
pp.332-344
Wilkinsonetal.TheClinicalEffectivenessofHealingTouch.TheJournalofAlternativeand Complementary Medicine. Volume 8, Number 1, 2002,pp.33-47
FitzHenry F, Wells N, Slater V, Dietrich MS, Wisawatapnimit P, ChakravarthyAB.
A randomized placebo-controlled pilot study of the impact of healing
touch on fatigue in breast cancer patients undergoing radiation therapy.
Integr Cancer Ther.2014;13:105-113.
Deng G et al., Acupuncture: integration into cancer care. J Soc Integr Oncol. 2006;4:86-92.
O’Reagan D, Fishie J. Acupuncture and cancer. Auton Neurosci.
2010;157:96-100.
VIckersAJetal.,Acupunctureforchronicpain:updateofanindividualpatientmeta-analysis.JPain. 2018;9:455-447.
Shalom Sharabi I, Samuels N, Lev E, Lavie O, Keinan-Boker L, Schiff E,
Ben-Arye E. Impact of a complementary/integrative medicine program on
the need for supportive cancer care-related medications. Supportive Carein Cancer 2017Oct;25(10):3181-3190.

AYURVEDA FOR A HEALTHY EUROPE:THE SIGNS AND SCIENCE OF WELLNESSAND LESSONS FROM INDIA’S
TRADITIONAL SYSTEMS OF HEALTH AND
WELLNESS AND INDIAN TRADITIONALSCIENCES INFORMING FUTURE
EUROPEAN AND GLOBAL HEALTHCARESYSTEMS, MEDICAL EDUCATION AND
RESEARCH
Madan Thangavelu PhD madan.thangavelu3@
gmail.com
Transdisciplinary University, Bengaluru, India,
General Secretary & Board Member for Research,
European Ayurveda Association &Former Trustee, Research Council for Complementary Medicine, UK

BOOK OF ABSTRACTS | 12th European Congress of Integrative Medicine · 1st International Symposium on Integrative Health and Education

Man is a metaorganism. Man’s health and wellbeing is shaped bycomplex and dynamic interactions within and without Man’s body.
Many of these interactions remain mysterious and many more will
currently be unfathomable. Despite the complexity of basic biochemical and physiological processes, dominant and recurring themes in all
cultures of the world are descriptions of the sense of feeling well anda wish for a state beyond good health. The descriptions of the state
and the feelings of wellness and wellbeing has been the focus of muchinterest formillennia.
India’s ancient texts offer graphic descriptions of this state as wellas prescriptions of how to achieve and maintain this state and steps
to prevent the deterioration of this state. India’s ancient system offer
comprehensive well-documented procedures and a holistic logic forthis state of wellness. The earliestSamhitasof Ayurveda and Yoga in particular and commentaries that followedcelebrate this state and offer some of the most profound descriptions
and definitions of thisstate. Nagarjuna’s 15-fold indicators of wellness are an early example. Dating back to 150 to 200 AD, the descriptions offered by Nagarjuna, the founder of the Madhyamaka school of Mahayana Buddhism
and an Ayurveda practitioner and scholar, are both timeless and invaluable. Are these and other rules which have guided many and offeredhealth beyond good health for centuries also valid
for contemporary living now and for the future? What might these
indicators look like when viewed through the eyes of contemporary
clinical biochemical and molecular descriptors? Can they be refined
further to help shape the Science of Wellness?
Advances in biochemistry over the last century, particularly thelast five decades have seen the birth and growth of techniques andtechnologies with resolution that far exceeds what was previously
imaginable. Single cells can now be routinely analysed for multiple
molecular markers. DNA changes can be ‘counted’ and enumerated
with the help of single DNA molecule resolution. Such technologies
are enabling finer, more sensitive and correlated analyses of innumerable biomolecules.
Are the ancient descriptors further refinable for understanding
and appreciating better the signs of wellness? Do they hold the key
to defining the deep science that governs the inextricably interlinked
major themes of food, exercise-fitness and health, the environment
and their links to the ethology and pathology of chronic non- communicable diseases?
Ayurveda, Yoga and other ancient Indian systems of health and wellness offer much guidance for the ways ahead.
By drawing on a small number of examples from contemporary
scientific research literature - from areas of sleep and health, food,the human microbiome and chronic diseases (obesity, diabetes, cardiovascular diseases, multiple sclerosis), seasons and changes in thehuman immune system, aging- related changes - I will show how
observations in contemporary science are entirely consistent withassertions in the ancient Indian texts about wellness and achieving,
maintaining and improving this state.
I will argue that the lessons from the highly refined, filtered and time-tested classical knowledge embodied in India’s ancient system of
health and wellness not only informs the future but offers the best
template for developing the much-needed new Science of Wellness
and also for disentangling and defining the four well separated sciences, namely the sciences of Cure, Prevention, Health Maintenanceand Health Promotion. These ancient systems also offer us the language, logic and grammar and a scaffold to hold the vast amounts ofhigh-quality data available today. In this way the Indian ancient sys-

21

tems of health and wellness and in particular Ayurveda offers muchfor human health and wellness and also solutions to complex problems today that require novel thinking for a healthy Europe.

INTEGRATIVE ONCOLOGY:
INTERNACIONAL AND EUROPEANPERSPECTIVES.
Elio Rossi** Homeopathic Clinic of the Hospital Campo di Marte, Lucca (Italy) – Regional center of reference for homeopathy. Coordination center for Complementary
Medicine of ASL Tuscany North West
Introduction.
Complementary and Integrative Medicine (CIM) use by patientswith cancer in Western Europe is estimated to be 37% but varies considerably across the different European countries, with higher prevalence in Germanspeaking (41%) and Mediterranean (39%) countries
and lower prevalence in the United Kingdom (32%) and Scandinavia(31%).
Aim.
To define the European integrative oncology (IO) landscape and theexperience of integration of Complementary edicine in cancer care in
Italy and particularly in the Tuscan Region.
Methods
A 2012 survey reported that around 105 NHS cancer services were
offering CIM.
Results
A mapping study conducted in 2013 captured those European cancercare services providing IO services.Informationfrom123(52.1%)
ofthe236cancercenterscontactedfoundthatnearlyhalfof the responding centers (47.5%) provided IO services. IO services were predominantly provided by the public health sector (69.9%), followed bya smaller number of privately owned centers (19.6%). Themostfrequently providedtherapywasacupuncture(55.3%).Treatmentsweremainlydirectedat reducingadversereactionstochemotherapyandradiation(23.9%),inparticularnauseaandvomiting (13.4%), pain (10.9%)
and fatigue (10.9%), secondary symptoms of iatrogenic menopause(8.8%), and anxiety and depression(5.9%).
In Italy some regions are integrating CIM into the public hospital systems. In a survey of the region of Tuscany, 91 public clinics providing
CIM services were identified. CIM was provided after the payment ofa fee similar to the other medical specialties (24€), but it was free ofcharge for patients with cancer, with the remaining costs being covered by the public health system. Like many pharmaceuticals, natural
products incur out-of-pocket costs (eg, homeopathic, herbal medicines, dietary supplements).
Conclusion
The presence of IO services in public and private hospitals acrossEurope, where oncologists and experts of CIM work side by side, hashelped overcome many cultural barriers and mutual distrust.

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BOOK OF ABSTRACTS | 12th European Congress of Integrative Medicine · 1st International Symposium on Integrative Health and Education

VITAMIN C FROM MICRONUTRIENTTO ESSENTIAL MACRONUTRIENT.
CHANGING THE PARADIGM
Arturo O’Byrne MD. Colombia
Profesor de cátedra en Medicina Integrativa. Universidad Javeriana. Colombia.
Since the work conducted by Levine in the NIH in the USA, 300 mg
was considered as the recommended daily allowance for ascorbate. Today we know that these studies were conducted without theknowledge that vitamin C is NOT distributed evenlythroughout the
bodyand that there are cells such as leukocytes which have active
pumps to obtain vitamin C in states of systemic deficiency.
One thing is the daily need in order not to develop scurvy and another thing is the referenceforneedsaccordingtothesituationorconditionthatthebodyisexperiencing. Animals capable of synthesising thevitamin have shown that they produce variable amounts based on
situations such as illness or physiologicaldemand.
It is therefore a mistake to consider the RDA as the ideal.
Situations such as inflammation and infection require increasing
the intake significantly while IV macrodoses are necessary in certain
cases such as sepsis.
Another fundamental point is understanding the antioxidant andprooxidant response ofvitaminCinrelationtothetherapeuticdoseadministered.Thisiscurrentlyoneofthe biggest points of confusion, especially in cancertreatments.
AnimportantbodyofevidencesupportstheneedforIVpharmacologicaluse,giventhat intestinal absorption is a limiting factor for oral doses, where the vitamin only reaches saturation levels of 220 umol/L.
On the other hand the levels can reach up to13,000umol/Lwhenadministeredintravenously.Thisshowsthatthepharmacokinetics iscompletely different between the oral and intravenous pathways,
which must be a fundamental consideration when taking therapeuticdecisions.

INTEGRATIVE MEDICINE ABSTRACT
Prof. Dr Juan Carlos Crespo de la Rosa

Climatechangeistodaythemostimportantandseriousglobalenvironmentalproblemthatthe Earth suffers, It has an impact on all its minerals, in all its flora and fauna and also in human health.
Allergies increase. Autoimmune and degenerative diseases at earlier ages. The contamination follows a geometric progression, While
human adaptation is an arithmetic progression. We are living in ourorganism a process of biological adaptation.
We are the generation of history that has seen more changes in alife in all the orders of the history of mankind. We all have an unprecedented biological adptación process in human history.
We all have 400 to 700 blood trace substances, That 60 years ago
nobody had. 30 years ago The normal leukocyte figures were between 2,500-5000, today, some 15,000. A normal patient today, , 30
years ago I was studied.
Thisproblemisduetomultiplehumanactivities,ofwhicheachcountryisresponsibletoalesser or greater extent an Likewise, its effects arefelt by people, communities, and ecosystems around theworld.
WemustnamethefoodHomotixicidad.Abreathtakingindustrializa-

dadandrefineddiet,richin preservatives, stabilizers, thickeners, antioxidants, dyes, flavourings and a long etcetera with a large numberof substancesmarketed.
The level of chemical intoxication is based on bioaccumulation as atendency for a substance to accumulate in the tissues of living organisms, To be related to the hydrophobic and lipofíicas characteristics.
There are seven toxicity criteria: 1. Acute lethality. 2. Sublethal
effects on non-mammalian species. 3. Sublethal effects on plants. 4.
Sublethal effects on mammals. 5. Teratogeneicidad 6. genotoxicity/
mutagenicity. 7. carcinogenicity.
All this makes us think, in the new challenge and justification of thesocial need today ofintegrative medical care.
Therefore, the proposed integrative medical revitalization presented in the countries of East Asia, north and South America and In some
European paise, with a great acceptance and evolution in the practiceof more than 25 years.
This method allows us to diagnose and treat, valuing the toxic,
structural, functional, metabolic and emotional status of our patient,, from the beginning of their alterations, allowing the practical practitioner, to jump standard protocols and to embody his way and Commitment to the therapeutic process of patients.
ThisistheproposaloftheR.M.I.in7guidelines:1.-Detoxify.2.-Searchforcurativeóbstales3.- Regulation of internal organs. 4.0-supplementation level. 5.-Changes in life habits for the promotion of epigenetic
changes. 6.-Aesthetic revitalization. 7.-Psychovitality: Modified relaxation techniques and NLP. (A.B.C. Exercises”toolbox”).
The seven phases are explained

DEVELOPMENTAL ORIGINS OF HEALTHAND DISEASE: THE IMPORTANCE OF
THE FIRST 100 DAYS OF LIFE
Author : María Del Mar Begara Morillas .Pediatrician, Expert in Pediatric Inten- sive Care, Homeopathy, Ortomolecular nutrition, Microinmunoterapia Vocal of the Sociedad Española de Saludy Medicina Integrativa. Imsalud, Madrid, CS Numancia , and HM Hospitales, Madrid.
Abstract: The focus of this communication is on the earliest stagesof child de- velopment,theperiodfromconceptiontotheendofthechild’ssecondyear.This periodhasbecomeknownasthefirst1000days.
Thereasonforfocusingonthis specific period is the growing body ofevidence which shows that is the period of maximumdevelopmentalplasticity,andthereforetheperiodwiththegreatestpo- tential to affecthealth and wellbeing over the life course. Environmental expo- sures
to stress, malnutrition, or toxins during critical period of development
can have long term effects on health and wellbeing by programmingorgans, tissues orbodysystemstructuresorfunctionsinwaysthatincreasetheriskofmetabolic, cardiovascular,immunological,andneurobehavioraldisorders,andevencancer.
Thekeyconceptintheearlieststagesofdevelopmentis:Developmentalplastic- ity and the developmental origins of health and disease(DOHaD) hypothesis. One of the most significant features of humanbiology is our capacity to adapt to different social and physical environments. This capacity is known as develop- mental plasticity, and it

BOOK OF ABSTRACTS | 12th European Congress of Integrative Medicine · 1st International Symposium on Integrative Health and Education

is at its greatest in the first 1000 days of life, although we retain some
capacity to adapt throughout our lives. This capacity to adapt makes
the human both versatile and vulnerable, as these changes may be
adapted for the immediate environment, but they can come with longtermcost.
Adaptation involves a process known as biological embedding.
The first mechanism for biological embedding and developmental
programming is epigenetic change. Epigenetic changes determine
whether genes are ex- pressedornot(turnedonoroff).Inhumantheperiodofdevelopmentalplasticity is the most sensitive to environmental
epigeneticchanges.
Another form for biological embedding is telomeres length. Telomeres are shaped by our genes, but also respond to how he lives.
The second mechanism whereby environmental experiences become biological embeddedissynapticpruning.Theinitialsurgeinsynapticconnectionsbetween brainneuronsoccursafterbirth.Connectionsarestrengthenedthroughrecurrent used, and our experiences andenvironment determine which connections are usedmore,andthisbecomestrongerandenduring,whilethosethatarenotused become weak
and are fade away (synapticpruning).
TheDOHaDhypothesismaintainsthatthefetusnotonlyregistersthesechanges in the intrauterine environment. But also used this information as a kind of “weather forecast” from their mother that prepares them for the type of world in which they will have to live, andalters its phenotype accordingly. When the pre- natal and postnatal
environment do not match, predictive mismatch canoccur.
Thenewresearchhasrevealedwholeaspectsofbiologicalfunctioningthatwere not previously recognized as playing a role in development,such as telomere effects and the role of the microbiome. But also,
new research must be focus in integrate environmental influences inthe Developmental Origins of Health and Disease (DOHaD) paradigm.
Environmental factors that can affect developmen- tal plasticity include not only nutrition, the most studied factor, but also: stress, chemical exposures, infections, drugs,mycobiome.
Conclusion:
Neurodegenerative diseases, breast cancer, cardiovascular disease,metabolic syndrome, infertility, asthma and atopic disease, learning
disabilities, childhood cancer.immunological.problems…haveonethingincommon:itislikelythatthey have their origins partly during development as a result of environmental influ- ences, including alterednutrition, stress, drug, infections, and exposure to envi- ronmentalchemicalsinaperiod”windowofsensitivity”,thefirst1000daysoflife.
Therefore,theinterventionsinthisfirst100daysoflifecanplayanimportantrole in improving globalhealth.

References
Mandy M, Nyirenda M. Developmental Origins of Health and Disease: the relevance to developing na- tions. In Health. 2018;10(2):66–70.
doi:10.1093/inhealth/ihy006
Matoso V, Bargi-Souza P, Ivanski F, Romano MA & Romano RM. (2019).
Acrylamide: A review about its toxic effects in the light of Developmental
Origin of Health and Disease (DOHaD) concept. Food Chem , 283, 422-430.
PMID: 30722893DOI
Heindel JJ, Balbus J, Birnbaum L, et al. Developmental Origins of Health and Disease: Integrating Envi- ronmental Influences. Endocrinology.
2015;156(10):3416–3421.doi:10.1210/EN.2015-1394

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Rodríguez-Carrillo A., Mustieles V., Pérez-Lobato R., Molina-Molina J.M.,
Reina-Pérez I., Vela-Soria F., Rubio S., Olea N., FernándezM.F.
Bisphenol A and cognitive function in school-age boys: Is BPA predominantly related to behavior?
NeuroToxicology, Volume 74, 2019
Andrea C.GoreabKrittikaKrishnanbEndocrine-disrupting chemicals:
Effects on neuroendocrine systems and the neurobiology of socialbehavior
Topper VY, Reilly MP, Wagner LM, Thompson LM, Gillette R, Crews D,
Gore AC.Mol Social and neu- romolecular phenotypes are programmed byprenatal exposures to endocrine-disruptingchemicals.
Cell Endocrinol. 2019 Jan 5; 479:133-146. Epub 2018 Oct 1.Birnbaum LS, Miller MF. Prenatal Programming and Toxicity (PPTOX)Introduction. Endocrinology. 2015;156(10):3405–3407.doi:10.1210/
en.2015-1458
Georgieff MK, Brunette KE, Tran PV. Early life nutrition and neural plasticity. Dev Psychopathol. 2015;27(2):411–423.doi:10.1017/
S0954579415000061
MorenoVillaresJoséManuel.Losmilprimerosdíasdevidaylaprevencióndelaenfermedadeneladulto. Nutr. Hosp. [Internet]. 2016 [citado 2019 Jul 15]; 33( Suppl 4 ): 8-11. Disponible en: http://scielo.is-ciii.es/scielo.php?script=sci_arttext&pid=S021216112016001000003&lng=es. http://dx.doi.org/10.20960/nh.337

THE CONTRIBUTION OF CAM TO
REDUCE ANTIBIOTIC USE AND AMR
PROF. DR. E.W. BAARS1,2, MD, MSC
EPIDEMIOLOGY, PHD
1 University of Applied Sciences Leiden, Leiden,

The Netherlands (baars.e@hsleiden.nl)
2 Louis Bolk Institute, Bunnik, The Netherlands(e.baars@louisbolk.nl)
ABSTRACT
Objectives: To provide an overview of the evidence of the contribution of CAM to reduce antibiotic use and AMR in general and specifically for acute, uncomplicated respiratory tract infections (RTIs) basedon several studies. Materialandmethod:AnarrativereviewofCAMpreventionandtreatmentstrategiesofinfections;a retrospective study
on antibiotic prescription rates (CAM/IM vs conventional medicine
in the UK); a surveyamongEuropeanCAMexpertsandasystematicreviewofprescriptionratesofCAMtreatments toidentifyCAMbestpracticesforcoughandsorethroat;asystematicreviewofsystematicreviewsof
CAM treatment of acute, uncomplicated RTIs; a systematic reviewof qualitative studies on patient perspective on the use of CAM forthe treatment of acute RTIs; the development of information tools
fordoctors,pharmacistsandpatientstodecideonCAMtreatmentforURTIsaspartofshareddecision- making and/or self-management. Results: Key results of all studies will be presented. Discussion: Thereis a promising contribution of CAM on prevention and treatment of
infections, appropriate use of antibiotics, and reduction of antibiotic
use and AMR. More high-quality research is necessary.
Conclusions:Therearepromisingevidence-basedandexpertise-basedCAMpreventionandtreatment strategiesforinfections;andCAMinformationtoolsfordoctors,pharmacistsandpatients,supportingthedecision-making process. In order for these contributions to achieve
their full potential, there is a needfor:betterqualityevidenceonsa-

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BOOK OF ABSTRACTS | 12th European Congress of Integrative Medicine · 1st International Symposium on Integrative Health and Education

fetyandeffectivenessofCAMtreatmentsforinfections;making use ofboth CAM expertise and results of clinical research on CAM complex
interventions and specific CAM treatment for specific indications;tested and implemented information tools for doctors, pharmacists
and patients; awareness raising about risks of inappropriate use ofantibiotics and informationwithrespecttosafealternativestrategies,includingdelayedprescription,withorwithout CAM treatments, andself-medication.

HOW DOES REFLEXOLOGY HELPCHILDREN WITH CANCER?
Dr. Bibiana Carrasco Paediatric Surgeon and Reflexologist
Hospital Sant Joan de Déu, a university children’s
hospital in Barcelona, offers many activities to improve the well-being of children. Since 2004 AFANOC -the Catalan Association for Children with
Cancer- is offering reflexology to children admitted in the onco-haemathology ward, in agreement with hospital officers andoncologists.
A team of five reflexologists visit the ward every week with the aimof giving a relaxing and pleasant massage and providing a feeling ofwell-being, at least for a time, to children on oncologic treatment. We
are not trying to find a cure to their disease in any way.
In the begining, neither the patients’ families nor the health professionals -medical and nursing staff- knew what benefits this techniquecould offer. Over the years we have gained respect and acceptancefrom the health workers, and particularly from patients and theirfamilies.
The children look forward to our visit and demonstrate their excitement. They realise the changes and feel the benefits they get throughreflexology. They don’t know how to put into words the effects theyfeel, but they do say this is one of the best activities in the hospital.
In the nightmare of a hard illnes, the families express gratittude forgetting the plus of reflexology, such a different and pleasant way ofcaring.
Along the years of experience we have observed that reflexology
provides the following: 1- For the children:-Relaxation and well-being-Helps them recover their wishes anddesires-Some improvement in: constipation, sleep, pain,mood 2-For thefamilies:-Support: feeling that they are not alone 3-For the healthprofessionals:-Complement and support for other aspectes of the childrens’health 4-For thereflexologists:-Rewarding-Experience-Training
We can conclude that reflexology offers a little breathing space
during the course of disease, which is a great help in the process ofseriously sick children and theirfamilies.

PROMISING NEW INSIGHTS, THERAPIES,AND TESTS FOR AUTISM AND PDD
William Shaw, Ph.D., Board certified in the fields
of clinical chemistry and toxicology by the American Board of Clinical Chemistry.
New technologies have revealed significant new factors as causesof autism spectrum disorders (ASD) including genomics, proteomics,
and metabolomics, and disciplines involved in mass screening of genes, proteins, and metabolic processes in humans. These technologies have already led to new therapeutic trials for ASD. In addition, anumber of recent studies have implicated both environmental factors
and genetic factors related to detoxification as critical in ASD. One of
the most promising discoveries has been the finding that the majority
of individuals on the autism spectrum are deficient in cholesterol andhave abnormal amounts of cholesterol transport proteins. A recent
article indicates that cholesterol supplementationshould be considered in all cases of ASD. Treatment of severe deficiency has led to reductions of infections, and improvements in sleep, social interactions,and growth. Behavior improvements include reduction in self-hurtfulbehavior, temper tantrums, aggressive behavior, and hyperactivity.
Cholesterol is a critical factor in myelin production needed for brain
growth and development, a cofactor in the brain development protein sonic hedgehog, a precursor of all steroid hormones and bilesalts, and a critical factor in the function of serotonin and oxytocin
receptors. Oxytocin, a hormone that stimulates social interaction andtrust, has been found to be low in the blood of children with autism.
Supplementation of oxytocin reduces autistic behaviors; combining
cholesterol and oxytocin may be an especially effectivetreatment.
Learning Objectives:
Learn why cholesterol is an essential nutrient necessary for growth,development, and normal behavior.
Understand the evidence for abnormal cholesterol production and/or transport in different types of autism and treatments that are currentlyavailable.

NON TYPICAL CARDIOVASCULAR RISKFACTORS. EARLY DETECTION IS NOTPREVENTION. FACTORES ATÍPICOS DERIESGO CARDIOVASCULAR; DETECCIÓN
PRECOZ NO ES IGUAL A PREVENCIÓN.
Dr Sergio Mejía Viana MD, PhD, FESC. Cardiolog
consultant
Gibraltar and Spain (Málaga, Madrid)www.
drsergiomejiaviana.com
Introduction
Atherogenesis is a multifactorial pathophysiological process of thearterial vasculature, which is characterized by progression from inflammation and smooth muscle cell proliferation to late stages that

BOOK OF ABSTRACTS | 12th European Congress of Integrative Medicine · 1st International Symposium on Integrative Health and Education

are marked by thrombotic and fibrotic obliterations of the vessels.
Examination of the earliest cellular events than occur during atherogenesis has demonstrated a specialized type of chronic inflammatory
response that precedes migration and proliferation of arterial smoothmuscle cells. The first observable events include increased accumulation of lipid and lipoprotein particles beneath the endothelium, presumably from increased transport and/or permeability of the lining
endothelial cells. This event is rapidly followed by attachment, adherence and spreading of peripheral blood monocytes and T-lymphocytes at sites throughout the arterial tree.
Since Framingham we are assuming that age, smoking, high blood
cholesterol, hypertension, diabetes, obesity and family history are themain risk factors for cardiovascular disease, stroke and atherosclerosis. In spite of aggressive strategies, medication for cholesterol, diabetes and hypertension, and low fat diet approach, the incidence of
cardiovascular disease is on the rise in western countries.
Numerous prospective epidemiological studies have identified adirect relationship between serum total cholesterol level and coronary heart disease incidence. Since the Framingham study it has long
been considered common knowledge that total serum cholesterol
is a strong independent risk factor for cardiovascular disease. This
study started in 1948 and has been cited thousands of times as oneof the most important epidemiological sources in the risk factors field.
During the last decades, cardiovascular disease prevention has beenmarked by a trend of gradually lowering thresholds of cholesterol levels.
We must understand that atherosclerosis is not a single disease
entity. In fact, the lesions of atherosclerosis represent a common response of the artery to numerous and potentially different forms ofinsult. Examination of atherosclerotic lesions reveal that each lesion
contains the elements of an inflammatory response together withvarying levels of fibro proliferative response. In order to get to the real
origin of this disease we must identify the whole spectrum of mechanisms involved in the development and progression, knowing thatearly detection is not always prevention. When a screening test detects the disease, it is good for prognostic reasons but it is late in terms
of primary prevention, therefore we use “secondary prevention”.
Is cholesterol the “bad guy”?
Cholesterol is the precursor of multiple hormones and vitamins:
Adrenal hormones (cortisol and aldosterone), sexual hormones (Estrogens, progesterone and testosterone) and vitamin
D. The mentioned hormones are synthesized through minor modifications of the cholesterol molecule in adrenal, ovarian and testicular
cells. And vitamin D metabolism starts in the skin cells by the activation of cholesterol by sunlight. Moreover, cholesterol is the precursorof five bile acids that help in digestion by facilitating the absorptionof fats and acting as transcription factors that take control on steroids
levels and COX-2 synthesis.
Cholesterol is a primary constituent that provides cell membranes
with their integrity. Without adequate cholesterol, cells will literally
leak, falling apart in the bloodstream. Another critical function of cholesterol is to serve as an anti-inflammatory, preventing the formationof pro- inflammatory lipids, which when left unregulated generatehigh amounts of free radicals. Thromboxanes are members of theeicosanoids signaling molecules which are the result of oxidation.
Thromboxanes are vasoconstrictors, causing platelet aggregation as
well as agglutination of red blood cells. Leukotrienes and prostaglandins are also fatty acid signaling molecules that are strongly involved in25

inflammatory responses. Each of these 3 proinflammatory fatty acids
are inhibited by adequate cholesterol levels.
Cholesterol is a major constituent of the human brain, and the brain
is the most cholesterol- rich organ. Numerous lipoprotein receptors
and apolipoproteins are expressed in the brain. Cholesterol is tightly
regulated between the major brain cells and is essential for normal
brain development. The metabolism of brain cholesterol differs markedly from that of other tissues. Brain cholesterol is primarily derived
by de novosynthesis and the blood brain barrier prevents the uptakeof lipoprotein cholesterol from the circulation. Defects in cholesterol
metabolism lead to structural and functional central nervous systemdiseases such as Smith-Lemli-Opitz syndrome, Niemann-Pick type C
disease, and Alzheimer’s disease. Cholesterol is tightly regulated between the major brain cells— neurons and glia, that is, astrocytes,
microglia, and oligodendrocytes—and is essential for normal brain
development. Cholesterol is required for synapse and dendrite formation and for axonal guidance. Cholesterol depletion leads to synaptic
and dendritic spine degeneration, failed neurotransmission, and decreased synaptic plasticity.
Non typical risk factors. Heavy metals.
There are more than 30 metals that are of concern for environmental authorities because of residential or occupational exposure, out of
which 23 are heavy metals: antimony, arsenic, bismuth, cadmium, cerium, chromium, cobalt, copper, gallium, gold, iron, lead, manganese,
mercury, nickel, platinum, silver, tellurium, thallium, tin, uranium,
vanadium, and zinc. These heavy metals are commonly found in theenvironment and diet. In small amounts they are required for maintaining good health but in larger amounts they can become toxic or
dangerous. Heavy metal toxicity can lower energy levels and damage
the functioning of the brain, lungs, heart, blood vessels, kidney, liver,blood composition and other important organs.
Population studies have demonstrated a link between lead exposure and subsequent development of hypertension and cardiovascular disease. In vivo and in vitro studies have shown that chronic
lead exposure causes HTN and cardiovascular disease by promoting
oxidative stress, limiting nitric oxide availability, impairing nitric oxidesignalling, augmenting adrenergic activity, increasing endothelin production, altering the renin-angiotensin system, raising vasoconstrictor prostaglandins, lowering vasodilator prostaglandins, promoting
inflammation, disturbing vascular smooth muscle calcium signalling,
diminishing endotheliumdependent vasorelaxation, and modifying
the vascular response to vasoactive agonists. Moreover, lead has beenshown to cause endothelial injury, impede endothelial repair, inhibit
angiogenesis, reduce endothelial cell growth, suppress proteoglycanproduction, stimulate vascular smooth muscle cell proliferation andphenotypic transformation, reduce tissue plasminogen activator, andraise plasminogen activator inhibitor-1 production. Via these and other actions, lead exposure causes hypertension and promotes atherosclerosis, thrombosis, and cardiovascular disease.
Cadmium is a by-product of zinc production which humans or animals may get exposed to at work or in the environment. Once thismetal gets absorbed by humans, it will accumulate inside the bodythroughout life. This metal was first used in World War I as a substitutefor tin and in paint industries as a pigment. In today’s scenario, it isalso being used in rechargeable batteries, for special alloys production
and also present in tobacco smoke. Cadmium is a highly toxic nonessential heavy metal that is well recognized for its adverse influenceon the enzymatic systems of cells, oxidative stress and for inducing
nutritional deficiency. Smokers are more susceptible for cadmium in-

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BOOK OF ABSTRACTS | 12th European Congress of Integrative Medicine · 1st International Symposium on Integrative Health and Education

toxication than non-smokers. Tobacco is the main source of cadmium
uptake in smokers as tobacco plants, like other plants, can accumulate
cadmium from the soil. Non-smokers are exposed to cadmium via
food and some other pathways. Studies in the last decade have shownthat cadmium levels in blood and urine are independent factors associated with the development of atherosclerotic plaques at baseline aswell as prospectively. This novel observation emphasizes the need toconsider cadmium as a proatherogenic pollutant.
Ascorbate deficiency.
The response-to-injury hypothesis of atherosclerosis states thatthe protective inflammatory response followed by the formation ofa fibro proliferative response begins as a protective mechanism thatwith time and continuing insult may become excessive. According toNobel prize winner Linus Pauling, the primary cause of human cardiovascular disease is a deficiency in ascorbate leading to the depositionof Lipoproteins -Lp(a)- and fibrinogen/fibrin in the vascular wall. The
total depletion of ascorbate in scurvy, leads to a complete loss of theintegrity and stability of the vascular wall and to the extravasation ofblood into the perivascular area. Ascorbate deficiency leads to an incomplete hydroxylation and thus weakens the extracellular matrix. Alterations of the endothelium and loose connective tissue are known
to be characteristic features of atherosclerotic plaques.
This theory states that human atherosclerosis can be primarily adegenerative disease initiated by ascorbate deficiency. This deficiency is the result of the inability of humans to synthesize endogenous
ascorbate combined with an insufficient dietary ascorbate intake and/or its destruction by habits like cigarette smoking. It is already known
that one cigarette destroys 250 mgs of Vitamin C in the body. Vitamin C is required for strong collagen in the lysyl hydroxylase pathway,
an enzyme responsible for attaching the lysine residues together on
adjacent collagen strands. Vitamin C deficiency results in weakened
collagen strands caused by disrupted lysine crosslinking.
It is then controversial for some investigators that found useless thestrategy of lowering LDL for atherosclerosis prevention. The most important of these investigators is the already mentioned Dr Linus Pauling who in 1989 announced a breakthrough in how we view and treat
heart disease. In the article “A Unified Theory of Human Cardiovascular Disease,” Linus Pauling announced that the deposits of plaqueseen in atherosclerosis were not the cause of heart disease, but wereactually the result of our bodies trying to repair the damage caused
by long-term vitamin C deficiency. In essence, Pauling believed thatatherosclerosis is a form of scurvy, and plaque is the body’s attempt toreinforce and patch weakened blood vessels and arteries that would
otherwise rupture. Pauling also showed that heart disease can be prevented or treated by taking vitamin C and other micronutrients.
Vitamin K2 deficiency.
More than seven decades ago, while investigating the effects of alow-fat diet fed to chickens, Danish scientist Henrik Dam discovered vitamin K. He found that the bleeding tendencies found in the chickens
on that diet could be prevented when a diet with normal levels of fat
was restored and vitamin K was added to their diets. From that point
forward, vitamin K became known as the coagulation vitamin, the “K”
coming from the German word koagulation. Vitamin K is not a single
entity but, rather, a family of structurally related molecules derived
from different sources. There are two main forms of the vitamin. Phylloquinone (K1) is found in leafy green plants and menaquinone (K2) isfound in animal meat and fermented foods.
Since 1950, the consumption of vitamin K has decreased grad-ually, and even a well- balanced diet might not provide vitamin K inamounts sufficient for satisfying the body’s needs. The population
based Rotterdam study studied 4807 healthy men and women older
than age 55 years, evaluating the relationship between dietary intake
of vitamin K and aortic calcification, heart disease, and all-cause mortality. The study revealed that high dietary intake of vitamin K2-at least
32 mcg per day, with no intake of vitamin K1, was associated with a
50% reduction in death from cardiovascular issues related to arterial
calcification and a 25% reduction in all-cause mortality.
Vitamin K2’s biological role is to help move calcium into the properareas in your body, such as your bones and teeth. It also plays a role inremoving calcium from areas where it shouldn’t be, such as in arteries
and soft tissues. Vitamin K2 protects arteries from calcification andwithout it plaque levels worsen. The vitamin K-dependent protein,matrix GLA protein, is a central calcification inhibitor produced by thecells of vascular smooth muscles and regulates the potentially fatal
accumulation of calcium.
Calcium intake.
A direct relationship between total calcium intake (diet plus
supplements) and cardiovascular disease (CVD), however, has notbeen established, and this issue remains controversial. Recent evidence derived from randomized, controlled trials, including the
Women’s Health Initiative, have raised a concern for an association between calcium supplement use and increased risk for CVD
events. Among calcium supplement users, a high intake of calcium greater than 1400 mg/day has been reported to be associatedwith higher death rates from all causes, including from CVD.
Periodontal disease.
Several infectious diseases have been implicated as possibly
causing inflammation and heart disease. Three mutually exclusive periodontal classifications were defined based on the Russell
Periodontal Index: periodontitis, gingivitis, and periodontal health.
Several biological mechanisms through which periodontal disease
may cause CHD have been proposed as follows: the invasion into
endothelial coronary cells by oral microorganisms the harmfulcardiovascular effects of inflammatory response to periodontitis,or contributions of oral microorganisms to acute thromboembolic events during bacteremia. Infectious agents might conceivably
furnish inflammatory stimuli that accentuate atherogenesis. Acuteinfections can alter hemodynamics and the clotting and fibrinolytic systems in ways that can precipitate ischemic events. Chronic
extravascular infections (eg, gingivitis, prostatitis, bronchitis) canaugment extravascular production of inflammatory cytokines that
may accelerate the evolution of remote atherosclerotic lesions.
Many human plaques show signs of infection by microbial
agents such Chlamydia pneumoniae. Chlamydiae, when present
in the arterial plaque, may release lipopolysaccharide (endotoxin) and heat shock proteins that can stimulate the production ofproinflammatory mediators by vascular endothelial cells and SMCs
and infiltrating leukocytes alike. Dental disease is associated withan increased risk of coronary heart disease, particularly in youngmen. Whether this is a casual association is unclear. Common oral
periodontal bacteria, that is, Prevotella gingivalis and Prevotellaintermedia, may contribute to the injury and inflammation thatprovokes atherosclerosis. Chronic oral infections such as adultperiodontitis, may have importante long-term sequelae. Aactinobacillus actinomycetemcomitans, Porphyromonas gingivalis, Bacteroides forsythus and Prevotella intermedia have been detected

BOOK OF ABSTRACTS | 12th European Congress of Integrative Medicine · 1st International Symposium on Integrative Health and Education

in atheromatous plaques by PCR. It has also been recognized thatperiodontal diseases, which are chronic gram-negative infections,represent a risk factor for atherosclerosis and thromboembolic
events. Periodontal disease, once established, provides a biological burden of endotoxin and inflammatory cytokines which serve
to initiate and exacerbate atherogenesis and thromboembolic
events. Periodontitis and atherosclerosis have complex etiologies,
genetic and gender predispositions, and potentially share manyrisk factors, the most significant of which may be smoking status.

27

References.
Moore KJ, Tabas I. The Cellular Biology of Macrophages in Atherosclerosis. Cell. 2011; 145: 341-355.
Ross R. The pathogenesis of atherosclerosis: A perspective for the
1990s. Nature. 1993; 362: 801-809.
Stary HC, Chandler AB, Dinsmore RE, Fuster V, Glagov S, et al. A definition of advanced types of atherosclerotic lesions and a histologicalclassification of atherosclerosis. A report from the Committee on Vascular Lesions of the Council on Arteriosclerosis, American Heart Association. Circulation. 1995; 92: 1355-1374.
Stamler J, Wentworth D, Neaton JD. Is relationship between serum
cholesterol and risk of premature death from coronary heart disease
continous and graded? Findings in 356,222 primary screenees of theMultiple Risk Factor Intervention Trial (MRFIT). JAMA. 1986; 256: 28232828.
Reiner Z, Catapano AL, De Backer G, Graham I, Taskinen MR, et al.
ESC/EAS guidelines for the management of dyslipidaemias: the task for-que Med SC. 1999; 15: 1472-1475.
Neaton JD, Wentworth DN. Low serum cholesterol and risk of deathfrom AIDS. AIDS. 1997; 11: 929-930.
Ravnskov. High cholesterol may protect against infections and atherosclerosis. Q J Med. 2003; 96: 927-934.
Ravnskov U. The questionable role of saturated and polyunsaturated
fatty acids in cardiovascular disease. J Clin Epidemiol. 1998; 51: 443-460.
Fester L, Zhou L, Bütow A, Huber C, von Lossow R, et al. Cholesterol-promoted synaptogenesis requires the conversion of cholesterol to
estradiol in the hippocampus. Hippocampus. 2009; 19: 692–705.
C Goritz, DH Mauch, FW Pfrieger. Multiple mechanisms mediate cholesterol-induced synaptogenesis in a CNS neuron. Molecular and Cellular Neuroscience. 2005; 29: 190– 201.
EI Posse de Chaves, AE Rusinol, DE Vance, RB Campenot, et al. Roleof lipoproteins in the delivery of lipids to axons during axonal regeneration. The Journal of Biological Chemistry. 1997; 272: 30766–30773.
R Koudinov, NV Koudinova. Cholesterol homeostasis failure as a unifying cause of synaptic degeneration. Journal of the Neurological Sciences. 2005; 229-230: 233–240.
Matthias Orth, Stefano Bellosta. Cholesterol: Its Regulation andRole in Central Nervous System Disorders. Cholesterol. 2012; Article ID
292598.
Rath M, Pauling L. Solution to the Puzzle of Human Cardiovascular Disease: Its Primary Cause is Ascorbate defiency, leading to the depositionof lipoprotein(a) and fibrinogen / fibrin in the vascular wall. J OrthomolMed. 1991; 6: 125- 134.
Rath M, Pauling L. Immunological evidence for the accumulation of lipoprotein(a) in the atherosclerotic lesion of the hypoascorbemic guinea
pig. Proc Natl Acad Sci U S A. 1990; 87: 9388-9390.
Willis GC, Light AW, Gow WQS. Serial Arteriography in Atherosclerosis. Can Med Assoc J. 1954; 71: 562-568.
S Mejia Viana. Non Typical Risk Factors in Atherosclerosis and Coronary Disease. It Is Time to Open the Box and Look Outside. J Clin Trials
Cardiol. 2017; 4: 1-5.
Jaishankar M, Tseten T, Anbalagan N, Mathew BB, Beeregowda KN.
Toxicity, mechanism and health effects of some heavy metals. Interdiscip Toxicol. 2014; 7: 60-72.
Vazir ND. Mechanisms of lead-induced hypertension and cardiovascular disease. Am J Physiol Heart Circ Physiol. 2008; 295: H454-65.
Kishimoto T, Oguri T, Ueda D, Tada M. Effect of lead on tube formation by cultured human vascular endothelial cells. Arch Toxicol. 1995;
69: 718-721.
Kaji T, Ohkawara S, Nakajima M, Yamamoto C, Fujiwara Y, Miyajima S,
et al. Lead-induced alteration of heparan sulfate proteoglycans in cultured vascular endothelial cells. Toxicology. 1997; 118: 1-10.
Kaji T, Suzuki M, Yamamoto C, Mishima A, Sakamoto M, Kozuka H.
Severe damage of cultured vascular endothelial cell monolayer after
simultaneous exposure to cadmium and lead. Arch Environ Contam Toxicol. 1995; 28: 168-172.
Fagerberg B, Bergström G, Borén J, Barregard L. Cadmium exposure isaccompanied by increased prevalence and future growth of atherosclerotic plaques in 64-year-old women. J Intern Med. 2012; 272: 601-610.
Okuyama H, Langsojen P, Hamazaki T, Ogushi Y, Hama R, et al. Statinsstimulate atherosclerosis and heart failure: pharmacological mechanis-

ce for the management of dyslipidaemias of the European Society ofCardiology (ESC) and the European Atherosclerosis Society (EAS). Eur
Heart J. 2011; 32: 1769-1818.
Guyton AC, Hall JE. Textbook of medical physiology, 9th edn. Philadelphia: WB Saunders CO. 1997; 947-949.
Podevin P, Poupon R. Les acides biliaires modulentl expression géni-

ms. Expert Rev Clin Pharmacol. 2015; 8: 189-199.
Beulens JW, Bots ML, Atsma F, Bartelink ML, Prokop M, et al. Highdietary menaquinone intake is associated with reduced coronary calcification. Atherosclerosis. 2009; 203: 489- 493.
Geleijnse JM, Vermeer C, Grobbee DE, Schurgers LJ, Knapen MH, etal. Dietary intake of menaquinone is associated with a reduced risk ofConclusions.
The HUNT 2 study, a very well designed prospective study in
Scandinavia included 52.087 Norwegians, aged 20-74, that were
followed-up on cause-specific mortality for 10 years. This is510.297 person-years in total. The statistical power and the lackof conflict of interest make this a heavy evidence source, evenstronger than the classic Framingham. Based on their results, theyclearly contradict the popularized idea of a positive, linear relationship between cholesterol and fatal disease, and conclude thatthe underlying assumptions regarding cholesterol in clinical guidelines for prevention might be flawed. This study could suggest that,like any other substance in the body, like thyroid hormone for instance, total cholesterol should be in a balanced situation, not too
high, not too low. According to their presented results, between 5
and 7mmol L-1 would be the desired level. They reported an interesting low mortality rate among post-menopausal women with amean cholesterol level of 7 mmol L-1.
Voices from Scandinavia, Japan and other developed countries
are proclaiming that focusing prevention only in the so called typical risk factors is not enough. Besides stress, which is not mentioned in this talk but is by far the most dangerous risk factor of ourtimes, we should open the box and look outside to a wide variety
of non typical risk factors that are definitely involved in the atherosclerosis pathogenesis. This will provide additional knowledge tosucceed in cardiovascular diseases prevention for the future generations.

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coronary heart disease: the Rotterdam Study. J Nutr. 2004; 134: 31003105.
Zheng S, Zhangsuo L, Donghai W. The efficacy of vitamin K on vascular calcification for chronic renal failure patient receiving dialysis. Int J
Clin Exp Med. 2016; 9: 18092-18097.
Samelson EJ, Booth SL, Fox CS, Tucker KL, Wang TJ, et al. Calcium intake is not associated with increased coronary artery calcification: theFramingham Study. Am J Clin Nutr. 2012; 96: 1274–1280.
Lutsey PL, Michos ED. Vitamin D, calcium, and atherosclerotic risk:
evidence from serum levels and supplementation studies. Curr Atheroscler Rep. 2013; 15: 293.
Li K, Kaaks R, Linseisen J, Rohrmann S. Associations of dietary calcium
intake and calcium supplementation with myocardial infarction andstroke risk and overall cardiovascular mortality in the Heidelberg cohortof the European Prospective Investigation into Cancer and Nutrition
study (EPIC-Heidelberg). Heart. 2012; 98: 920–925.
Lewis JR, Calver J, Zhu K, Flicker L, Prince RL. Calcium supplementation and the risks of atherosclerotic vascular disease in older women:
results of a 5-year RCT and a 4.5- year follow-up. J Bone Miner Res.
2011; 26: 35–41.
Paik JM, Curhan GC, Sun Q, Rexrode KM, Manson JE, et al. Calcium
supplement intake and risk of cardiovascular disease in women. Osteoporos Int. 2014; 25: 2047–2056.
Hsia J, Heiss G, Ren H, Allison M, Dolan NC, et al; Women’s Health
Initiative I . Calcium/vitamin D supplementation and cardiovascular
events. Circulation. 2007; 115: 846– 854.
Nordin BE, Lewis JR, Daly RM, Horowitz J, Metcalfe A, et al. The calcium scare—what would Austin Bradford Hill have thought? OsteoporosInt. 2011; 22: 3073–3077.
Bolland MJ, Grey A, Avenell A, Gamble GD, Reid IR. Calcium supplements with or without vitamin D and risk of cardiovascular events:
reanalysis of the Women’s Health Initiative limited access dataset andmeta-analysis. BMJ. 2011; 342: d2040.
Bolland MJ, Avenell A, Baron JA, Grey A, MacLennan GS, et al. Effectof calcium supplements on risk of myocardial infarction and cardiovascular events: meta-analysis. BMJ. 2010; 341: c3691.
Michaelsson K, Melhus H, Warensjo Lemming E, Wolk A, Byberg L.
Long term calcium intake and rates of all cause and cardiovascular mortality: community based prospective longitudinal cohort study. BMJ.
2013; 346: f228.
Russell AL. A system of scoring for prevalence surveys of periodontal
disease. J Dent Res. 1956; 35: 350-359.
Dorn BR, Dunn Jr WA, Progulske-Fox A. Invasion of human coronary
artery cells by periodontal pathogens. Infect Immun. 1999; 67: 57925798.
Deshpande RG, Khan MB, Genco CA. Invasion of aortic and heart
endothelial cells by Porphyromonas gingivalis. Infect Immun. 1998; 66:
5337-5343.
Beck JD, Offenbacher S. Systemic effects of periodontitis: epidemiology of periodontal disease and cardiovascular disease. J Periodontol.
2005; 76: 2089-2100.
Mustapha IZ, Debrey S, Oladubu M, Ugarte R. Markers of systemic
bacterial exposure in periodontal disease and cardiovascular diseaserisk: a systematic review and meta- analysis. J Periodontol. 2007; 78:2289-2302.
Petursson H, Sigurdsson JA, Bengsson C, Nilsen T, Gletz L. Is the useof cholesterol in mortality risk algorithms in clinical guidelines valid? Ten
years prospective data from the Norwegian HUNT 2 study. J Eval Clin
Pract. 2012; 18: 159-168.

NEURAL THERAPY, VEGETATIVENERVOUS SYSTEM AND FASCIA: WIDE
SPECTRUM REGULATORY THERAPYDavid Vinyes1
MedicalDoctor.Director of theMaster DegreeinNeuralTherapyof theUniversityofBarcelona.Director of theInstituteof Neural Therapy, Sabadell(Catalonia).
Abstract
A reading of the text of Dr James Mackenzie, which was translated
into Spanish in Barcelona in 1914 [1], takes us back to a time where
the diagnosis was made almost entirely with direct patient contact.
This Englishsurgeon,aresearchprofessoratLondonHospital,conductedathoroughinvestigationassessingthe irritation of the central nervous
system by palpating hyperalgesic areas of the skin and muscles as wellas involuntary muscular contractions (visceromotor reflex); he also
evaluated pain in vertebral bodies and its relationship to disease processes, next checking this diagnostic approach in the surgical field andthe prognosis.
This course of action involved observing patients in a more individual fashion, always as patients rather thanasmedicalconditions,andseeingthemmoreholistically.Whatwassoughtwastheimpactofaprocess throughout the body, highlighting its manifestation on the skinand other palpable tissues such as muscles and vertebralbodies.
Recentresearchcarriedoutregardingthetransmissionofcellularsignalsinthebodythroughtheconnective tissues by the phenomena
known as mechanotransduction and piezoelectricity [2] – driven by
the fields of acupunctureandosteopathy–encourageustobeopenandtoincorporatemoretheimportanceofconnective tissues as a metasystem that connects not only structurally but also functionally all tissues
and organs of the body. The fascial system is a part of this connective
system and it also has a regulatory function just as the nervous and endocrine systems. It has never ceased to be a part of these systems[3].
Theoscillationsemittedbythegroundsubstanceinastateofimbalancecanbeperceivedbytheconnective tissue palpation. The different
composition, density of particles, extracellular matrix or ground substance proportion that exist in each area of the body reflects an affected organ and other related structures, either because they are origin
or compensation of the pathology.[4]Changes in pH, despolimerizations, waste not evacuated, deficiencies or excesses of molecules in ground substance… modified the displacement of the fluid, and that implies changes in its palpation. [4]Palpate, touch, listen to the patient provide important details in the
diagnostic process development and treatment plan [5]. But palpation is not merely about searching options of pain / no pain. It is one of
the waysinwhichwerelatetothepatientwhereby,aswellaslearninghowtofindtheirvisceralmanifestations through their reflexes, we place ourhand on their psychosomatic manifestations, on thetissues where
they express their emotions, not only on skin and muscle, and thismay also contribute to the approach and an increase oftrust.
InthispaperIwanttosharemydailyexperienceusingpalpationtosearchforpointsofgreatestconnective and fascia tension, relating themwith both visceral, mental and emotional components of the patient,and injectingtheretheprocaine0.5%toobservetheanswer.Oftentheresponseisimmediate,veryfast,andwe cansee itasagreatermovemen-

BOOK OF ABSTRACTS | 12th European Congress of Integrative Medicine · 1st International Symposium on Integrative Health and Education

tofthediaphragm,ageneralrelaxationofthemuscles,animprovementin
mood, an increase of peristalsis (frequently we hear the abdominalsounds as soon as we do the first puncture) and of feeling of bodytemperature, an improvement of pain, etc. All these are clear signs ofneurovegetativeunblocking.
Itsouldbenotedthattheseimprovementsandchangesdonot occuronlyinthesegmentspunctured,butin general, the same way that happens when an interference field isremoved.

References
Mackenzie, J., Los Síntomas y su Interpretación. Casa Editorial Estudio(1914),BarcelonaÁlvaro, T. et al., Extracellular matrix: morphology, function and biotensegrity. Rev Esp Patol2009;Vol 42, nº 4: 249-261
Dalmau,I.
G. Sacristán, Carmen et al., Conceptual progress of connective tissue andimpact on clinicalpractice.
Rev Int Acupuntura. 2013;7(3):78-84
Vergheses A, Brady E, Kapur CC, Horwitz RI. The bedside evaluation: ritual and reason. Ann Intern Med.2011;155(8):550-3.

WHOLE BODY DENTISTRY:THE MOUTH
AS A SOURCE OF “NOISE”
Dra Mar López Sala Licenciada en Medicina UAB. Licenciada en OdontologíaUB
The connection between mouth and body has for a long time beendenied, although in ancient times there was a more integrative understanding and physicians knew the link between bad oral healthand generaldiseases.
During the last 20 years this knowledge is emerging again and dentists begin to be considered as truly general health agents instead ofsimply technicians.
When general health is affected, specially due to chronic illnesses,
without a clear etiology, etiopathogeny and therefore without a clear
and effective treatment, a global “screening” of the possible interference fields, using the Neuraltherapy according to Huneke terminology, becomes inevitable.
One of the most probable places to find irritant factors is the oralcavity, since oral problems are between the most prevalent diseases.
Differentsituationsmaycontributetothedeteriorationof oralhealth,beingcavities,periodontaldisease,theuseofdifferent materials for dentistry, some of which are toxic for some people, pathologicalocclusionandtemporomandibulardisordersleadingto postural and structureanomalies, and infected teeth or endodontically treated teeth, among
the mostcommon.
The dentist should be able to detect all of these factors and prioritizewhatismoreimportanttotreatortoeradicateinorderto achieve thetotal elimination of which is called “noise”, meaning irritant factors
affecting general health through the autonomic nervoussystemandtheextracellularmatrixandgroundregulation system.
Theaimofthispresentationistobringthisconnectioncloserto healthprofessionalsdedicatedtointegrativemedicine

29

OZONOTHERAPY IN HUMAN
PAPILLOMAVIRUS (HPV) INFECTION
Adriana Schwartz. MD. Obstetric-Gynecologist.
Director, Fiorela Clinic “Medical Center of PainManagement. Madrid- Spain
For correspondence: adriana@aepromo.org
Abstract
Study of 30 patients infected with human papillomavirus (HPV)
without having spontaneousremissionafteroneyearasofthefirstdiagnosis.Thesampleswerecollected between October 2014 and February
2017. Cervical swabs were analyzed both HPV genotyping by PCR andReverse Line Blot, and cervical cytology by Paptesting.
The study was carried out with the objective of verify the efficacy of
O2 / O3 alone and in combination with other complementary measures. The patients were divided into two groups.
a) Group O3 + (treated with ozone plus integrative therapy): It was
treated with intravaginal ozone, ozonated saline solution, micro-immunotherapy and administration IV of GSH, Se, Zinc and VitC.
b) Ozone group (treated exclusively with ozone): It was administered with intravaginal ozone therapy alone. Although the number ofpatients does not allow a safe conclusion, the group of patients treated with ozone plus integrative therapy presented a great advantages(p˂0,05) compared to the group of patients treated exclusively withozone.
Positive (negative cytology after 3 months of finishing the therapy)
Group O3 + (patients treated with ozone plus integrative therapy):16 de 20 =>80.0 %´Ozone group (patients treated exclusively with ozone): 6 de 10 =>60.0 %
It was shown that the synergy of the ozone therapy with the othertreatments was more effective, permanent and harmless than theapplication of intravaginal ozone alone.
Key words: Intravaginal ozone, ozonized oil, Human Papilloma Virus, Ozonated Saline Solution, genotype 16, 18, Condiloma Acuminata, ozone therapy, womb cancer.

Bibliography
Choi YJ et al. Clinical significance of human papillomavirus genotyping. J
Gynecol Oncol. 2016Mar;27(2):e21.
Hibma MH. The immune response to papillomavirus during infection
persistence and regression. Open Virol J.2012;6:241-8.
Zhang L et al. The role of the PI3K/Akt/mTOR signalling pathway in human cancers induced by infection with human papillomaviruses. Mol Cancer. 2015 Apr17;14:87
M. Moyal-Barracco,M. Leibowitch,G. Orth Vestibular papillae of the vulva. Lack of evidence for human papillomavirusetiology.
Thomas G et al. Efficacity of 2L-PAPI, a micro-immunotherapy drug, inpatients with high-risk papillomavirus genital infection. Adv. in Infect. Dis.
2016;6:7-14
W.A. Growdon,Y.S. Fu,T.B. Lebherz,A. Rapkin,G.D. Mason,G. Parks Pruritic
vulvar squamous papillomatosis: evidence for human papillomavirus etiology Obstet Gynecol, 66 (1985), pp. 564-568 Medline.
Danelian C.J. Prevención de las infecciones post parto con el uso delozono médico. Disertación de tesis doctoral. Moscú 2004. 175 páginas
Grechkanev 44. G.O. Fundamentos científicos del uso del ozono médico

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BOOK OF ABSTRACTS | 12th European Congress of Integrative Medicine · 1st International Symposium on Integrative Health and Educationen el complejo de tratamiento de algunas complicaciones obstétricas y enfermedades ginecológicas. Defensa de tesis doctoral en Ciencias Médicas.
Moscú,2003.
Schwartz, Adriana (2016), Solución Salina Ozonizada (SSO3); Fundamentos Científicos. Revista Española de Ozonoterapia Vol. 6, nº1, pp.111-120
Lezcano I, García G, Martínez G, Moleiro J. Efectividad del aceite de teobroma, OZONOL, ozonizada para el tratamiento de la candidiasis vaginal.
Revista CENIC Ciencias Biológicas1998;29:211.
Emma J Crosbie et al. “Human papillomavirus and cervical cancer”. The
Lancet, Vol 382 September 7, 2013. pp889-899
Bruni L, Barrionuevo-Rosas L, Albero G, Aldea M, Serrano B, Valencia
S, Brotons M, Mena M, Cosano R, Muñoz J, Bosch FX, de Sanjosé S, Castellsagué X. ICO Information Centre on HPV and Cancer (HPV Information
Centre). Human Papillomavirus and Related Diseases in Country. Summary
Report 15 December 2016.http://www.hpvcentre.net/statistics/reports/
ESP_FS.pdf
WMA. World Medical Association Declaration of Helsinki. Ethical Principles for Medical Research Involving Human Subjects. Adopted by the 18th
WMA General Assembly, Helsinki, Finland, June 1964: J Int Bioethique;2004. p.124-29.

INTEGRATIVE APPROACH OF
PREMENSTRUAL SYNDROME
Dr. Alejandra Menassa de Lucia. Internist. CMI. Integrative Medicine Clinic.
Keywords: Premenstrual syndrome, Premenstrual Disforic disorder,
Ozone Therapy, Intrauterine Ozone Therapy.
PMS can affect up to 30% of the female population of childbearing
age. Its most severe form can lead to incapacity for work. Since conventional medicine there is no truly effective treatment. For someauthors, it is a pathology that begins in an infectious/inflammatory
uterine process. Therefore, the objective of the work was to evaluate
the potential efficacy of ozone in its approach.
The patients were recruited from among those who attended CMI
for premenstrual syndrome. With an n=9. A premenstrual syndrome
questionnaire was applied to all of them, before and after treatment.
Rectal ozone therapy, AHTM and intrauterine techniqueswerecombined.Theywerealsotreatedwithorthomolecularsupplementation.
PGE2 and AA (prostaglandin E2 and arachidonic acid) were measured
in the uterus and pathogenic intestinal or sexually transmitted germs
or vaginitis/cervicitis were determined by medtronic bioresonancemethods at the beginning, middle and end of treatment.
Questionnaires showed improvement in most symptoms, a highpercentage (more than 60%)disappeared,20%improvedmarkedly,and20%didnotchangeaftertreatment.The disappearance of depressive
and anxious symptoms in most patients was very striking. ThemeasurementofPGE2andAAinuterodecreasedin100%of thepatients,indicating a reduction in inflammation. Intestinal pathogens were alsoreduced.
Ozone therapy significantly reduces the symptoms of premenstrual
syndrome, it is also likely to improve or resolve mental symptoms by
its action on neurotransmitters.
BIBLIOGRAPHY:
Dalton, K. The Premenstrual Syndrome. British medical journal. London.
Saturday may 9,1953.
Toth, A. et als. Effect of Doxycycline on Pre-Menstrual Syndrome: A Double-Blind Randomized Clinical. Journal of International Medical Research

1988 16:270.
3. Lolas- Talhami, J. Premenstrual Syndrome: An Ignored Public
HealthProblem.
. Revista Médica de Chile. Vol. 121(5): 560-566. 1993 [PMID 8272641]
Lolas Talhami, J. Premenstrual Syndrome from a new perspective: A cyclic, inflammatory and multisystemic picture. Second edition. Chile2017.
Bertone Jhonson, E. et als. Association of inflammation markers withmenstrual symptom severity and premenstrual syndrome in young women. Human Reproduction, Vol.29, No.9 pp. 1987–1994,2014.
Alvergne, A, Vlajic Wheeler, M Högqvist Tabor, V Do sexually transmitted infections exacerbate negative premenstrualsymptoms?
Perspectives of digital health. Evolution, Medicine and Public Health,
Volume 2018, Number 1, January 1, 2018, pages 138-150, https://doi.
org/10.1093/emph/eoy018
Doyle, C. Sexually Transmitted Pathogens, Depression, and OtherManifestations Associated with Premenstrual Syndrome. Hum Nat. 2015 Sep; 26(3): 277-91. doi: 10.1007 /s12110-015-9238-3.
Kunc, M. et als. Microbiome impact on metabolism and function of sex,
thyroid, growth and parathyroid hormones. Acta ABP. BiochimicaPolonica.
Vol. 63, No 2/2016, 189–201, http://dx.doi.org/10.18388/
abp.2015_1093

ACUPUNCTURE AND FERTILITY IN
DEXEUS WOMEN’S UNIVERSITY CLINIC,
BARCELONA
Carvajal 1, G; Giralt, I 2.
1 MD, Anestesiology. Master en Acupuncture. 2
MD, acupuncture and natural medicine clinic Energimed. Health Acupuncture Unit Dexeus University Women’s Clinic (Barcelona/SP)
In this presentation we will review the current evidence of acupuncture as a complementary technique in the processes of assisted fertility.
We will also discuss the results of the work we have done at theDexeus Women’s ClinicinBarcelona,acenterspecializingingynecologyandfertilityandwheresince 2011 there is an Acupuncture Unit integrated into itsservices.
In this Unit we have treated integratively more than 200 womenwith fertility problems and we did some prospective studies comparing the result of using Acupuncture as a complement to the treatments with a similar group of patients who have not received.
As a result of these studies and the recent scientific articles we havecome to the conclusion that the use of Acupuncture as a complement
in women with fertility problems and especially with low ovarian reserve is preferably indicated in the phase prior to the embryo transfer,individually and if possible three or four menstrual cycles before to
start the stimulation.
The indication for post-transfer treatment is to control anxiety andalways using very soft needle insertion in points related to gynecological areas.
We will talk about the points used, in what cases we use electroacupuncture and where and treatment guidelines that we use in an

BOOK OF ABSTRACTS | 12th European Congress of Integrative Medicine · 1st International Symposium on Integrative Health and Education

integrated way in patients who wish to do at the Dexeus Women’s
University Clinic.

Stener-Victorin E, Waldenström U, Andersson SA, et al. Reduction ofblood flow impedance in the uterine arteries of infertile women with electro-acupuncture. Hum Reprod 1996;11:1314–7.
E.Paulus,etal.InfluenceofAcupunctureonthepregnancyrateinpatienswhoundergo assited reproduction therapy. Wolfgang E. Paulus, Fertility and Sterility, Vol. 77, Nº. 4,2002
Stener-Victorin et al. Acupuntucture has been shown to modulate thesympathetic nervoussystemaswellastheendocrineandneuroendocrinesystems.JApplPhysiology 2006
So EWS, Ng EHY, Wong YY, et al. A randomized double-blind comparison of real and placebo acupuncture in IVF treatment. Hum Reprod 2009;24:341–8. doi:10.1093/humrep/den380
SoEWS,NgEHY,WongYY,etal.Acupunctureforfrozen-thawedembryotransfercycles: a double-blind randomized controlled trial. Reprod Biomed Online 2010; 20:814–21. doi:10.1016/j.rbmo.2010.02.024
Cui Hong Zheng et al. Effects of acupuncture on pregnancy rates in women undergoing in vitro fertilization. Fertility and Sterility. Vol 97no3.2012
Carr D. Somatosensory stimulation and assisted reproduction. AcupunctMed 2015; 33:2–6.doi:10.1136/acupmed-2014-010739
Wang Y et al. Electroacupuncture for reproductive hormone levels in patiens with diminished ovarian reserve: a prospective observational study.
Acupunct Med 2016; 0:1-6
SmithCA,deLaceyS,ChapmanM,etal.EffectofAcupuncturevsShamAcupunctureon Live Births Among Women Undergoing In Vitro Fertilization: A Randomized Clinical Trial. JAMA 2018; 319:1990–8.doi:10.1001/
jama.2018.5336

REFLEXOLOGY AND ASSISTEDREPRODUCTION
Vives, C1, Esmel, N2
1Gynecologist and Obstetrician, specialist in Fertility and Reproductive Medicine. Sant Joan deReus Hospital and Embriogyn Prenatal Assisted
Human Reproduction and Prenatal Diagnosis Center. (Tarragona/SP)
2Phd, Reflexologist. Founder and director of theEsmel Therapy Center (Tarragona/SP)

The human race, with a 20% monthly fertility rate on average, isclearly not so fertile if we compare ourselves with other animal species. Between 10-15% of couples suffer from sterility, understood as
the difficulty to become pregnant after a year of concerted attempts.
Fortunately, thanks to assisted reproduction treatments, many ofthese couples end up being parents. Indeed, since the birth of Louise
Brown in 1978, the first baby conceived through in vitro fertilisation
until present, reproductive medicine has advanced to an extraordinary degree. The current accepted figure is more than 8 million people have been born through this technique around the world. But inspite of these important advances, especially in the field of biomedicine, biotechnology and genetics, the results of assisted reproduction
techniques are still quite limited. Approximately two out of every 3 invitro fertilisation attempts do not lead to pregnancy and this fact leads
to a great feeling of uncertainty, dissatisfaction and anguish both for31

the physicians as well as the patients.
In parallel, it is widely recognised that the condition of sterility andassisted reproduction treatments involve a heavy psychological burden and a poor quality of life. It is not clear if stress and anxiety act asaetiological factors in sterility or if they have an effect on assisted reproduction treatments. However, what is undoubtedly a fact is that aperson with a poor mental state is more likely to abandon an assisted
reproduction treatment or even not be able to start it, thereby clearly
reducing their possibility of becoming pregnant. In fact, it is acceptedthat psychological support should form part of the typical interdisciplinary work in the reproductive medical units and some pilot studies
have already explored the efficacy of integrative strategies such as
yoga or traditional Chinese medicine, observing beneficial results inthis sense.
Reflexology is a complementary and ancestral integrative therapy,
defined as an old Indian, Egyptian and Chinese method for diagnosis
and treatment, with origins around 3000 B.C. It is based on the belief
that the entire human body is represented in the feet (less frequently
the hands) and that by applying sufficient pressure on one’s toes (orfingers), specialists in reflexology can stimulate the body and promotea proper state of health.
The scarcity of highly rigorous scientific studies that can be foundpublished currently with regards both to the potential beneficial
effects of reflexology as well as to its clinical safety is both a fact anda great limitation. In general, reflexology is considered a highly safe
therapy although most works do
not address the topic of adverse effects. Even though there aresome randomised clinical trials where different positive effects ofreflexology have been observed in specific medical conditions, thequality of most of these studies has frequently been poor and with agenerally low sample size. On the other hand, most of the works with
top-tier methodology have not managed to observe the potential beneficial effects of reflexology. Consequently, we should be aware that,based on that medical evidence available at present, it is not possible
to convincingly show that reflexology is an effective treatment for any
medical condition.
However, at the same time, reflexology has been used traditionallyto try to help couples who have difficulties conceiving. Opinion articles and reports of particular cases are appearing in the non- medicalpress which suggest the ability of this ancient discipline to help in thefield of human reproduction and many couples have decided to undergo the treatment with varying degrees of success. In a certain way,
it could be understood as involving a more pleasant, more economical
and non-pharmacological alternative to the standard assisted reproduction treatments. Additionally, it seems that it could also help in thepsychological aspect by reducing the high level of anxiety in patientswith sterility problems.
In our current scenario, where we are still not capable of giving an
explanation to many of the failures of assisted reproduction treatments and being conscious of the associated heavy psychological burden, we consider it appropriate to research the potential beneficiaryeffect of reflexology on in vitro fertility treatments.
Two actions have been carried out in this regard. First, field work
has been carried out based on one survey addressed to physicians
who specialise in the field of assisted reproduction and on anotheraddressed to patients diagnosed with sterility, in order to have an ideaof the current situation of the issue of complementary therapies andfertility in our area of influence. Second, a prospective, randomised,double-blind clinical trial has been designed to assess the effect of reflexology applied in parallel with in vitro fertility treatments, both at

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BOOK OF ABSTRACTS | 12th European Congress of Integrative Medicine · 1st International Symposium on Integrative Health and Education

the medical and psychological level.
We therefore consider reflexology a safe discipline, with a still poorly defined physiology which, in spite of the insufficient level of evidence, has suggested a positive effect on different diseases according tomultiple works published. This has led us to question if it could contribute to improving the medical and psychological results of patientssubjected to assisted reproduction treatments. Given that there isno single work published in the scientific literature that contributes
information in this regard at present, we propose trying to produce
medical evidence concerning the topic, accepting the limitations in
the precise knowledge of the mechanism of action and focusing on
the observed results.

FERTILITY IS NOT ONLY EMBRYOQUALITY
Carmen Salgado Sánchez. Licenciada en Farmacia, especializada en Bioquímica, Master en Nutrición Ortomolecular. Profesora Real Centro Universitario Reina
Cristina. Directora técnica de Herbarum Natura
Introduction
In Spain 6000 couples have problems to conceive, that is, 1 out of
every 4 born in the 70 will not have children. This becomes a healthproblem.
Each year 16,000 couples need help with fertility treatments to become parents.
June is the world month of Fertility Care. I love this concept because
it’s not about working with infertility, but about caring for fertility.
Let’s start at the beginning (What is infertility?) Impossibility of a couple getting a pregnancy by natural means after having normal sex for
more than 1 year.
Why is this happening:
Spaniards delay motherhood from 26 years in 1985 to 31 yearsnow.
Regarding male fertility according to the European Fertility Society
until 1986, the normal number of sperm in the ejaculate was 100 million / cc. From 1986 this normality is reduced to 60 million / cc and since
1992 to 20 million /cc
There is no approach that works for everyone since each couple has
their ownsituation.
Focus only on ovulation
Many couples with fertility problems only have sex during the periodof ovulation: Some couples try to “save” the sperm during the period of
ovulation and then barely have sex during the month.
But the ideal is to have relationships every two or three days during
the month to maximize the possibilities.
Others believe that having more sex produces more possibilities but
this is not true. If it is for reproductivepurposes,havingsexseveraltimesadayoreveneverydaycancauseexhaustionand the couple can begin tosee sex as little more than a pre-ovulatorytask.
If you control the temperature or are using an ovulation prediction
kit, you may think that the idealis the day of ovulation. But it may belate because the ovum can be fertilized for 24 hours afterwards and thesperm survives up to 24 or 48 hours so it is highly recommended thatyou have intercourse every other day on days 4 to 6 days before ovulation and continue doing so for another 4 to 6 days afterthis.
The importance of endocrine disruptors.

Not cleanse of endocrine disruptors is one of the mistakes that can bemade in matters of infertility.
We remember that an endocrine disruptor is those substances exogenous to the organism (natural or synthetic) that interfere with the
production, transport or action of natural hormones in our organism.
Many times they behave like fake oestrogens or imitators
What are the main ones:-Aromatichydrocarbons-Halogenatedhydrocarbons-Organochlorine compounds:Pesticides-Heavy metals (lead,cadmium)
All these products are contained in pesticides, insecticides, food additives and cosmetics and hygiene products, environmental pollution,
platicos, UV filters of sun creams,
In male fertility affect the quality of sperm (remember that at least
half of cases of male sterility is of unknown cause) and could be attributed to these endocrine disruptors.
Inwomentheseendocrinedisruptorsaffecttheglandssuchasovaries,pancreas(insulinresistance and fertility, polycystic ovarian syndrome),
adrenal (cortisol and iflamation) and thyroid (thyroid disorders) andpituitary gland (high levels ofprolactin).
Contamination reaches newborns through the umbilical cord. According to a US study on umbilical cord blood from fetuses, these aresoaked in a mixture of chemicals that include (mercury, gasoline derivatives, pesticides and the chemical PFOA used in Teflon). Up to a total of
287 chemical contaminants.
The damage of endocrine disruptors can be transgenerational, thatis, diagnosed to newborns or adults who were exposed when their mother was developing them.
Hence the importance of making a history of environmental exposure in couples who have infertility problems.
A key point the hypophysis
The pituitary gland, which is located in the brain that controls our sex
hormones (estrogen, progesterone and prolactin) and is directly affected by our stress, anxiety and attitude towards life. And these therefore
directly affect our fertility.
It has been proven how yoga helps to rebalance the hormonal axes.
Meditation improves the rebalancing of neurological pathways that
influence hormonal control. Acupuncture produces endorphins that
help manage your stress, anxiety and daily emotions. These techniquesthat act from the mind help optimize the results of both natural fertility
but also assistedfertilitytreatmentsbecauseallthreehelptobalancethehormonalsystemwithouttheneed to take medicines orchemicals.
The importance of the immune system
The immune system is what defends us from the external aggressor
but also maintains an internal balance,allowsbloodvesselstoformatthetimeofimplantationandfirsttrimesterofpregnancyand these blood vessels respond to the immunesystem.
At the same time there are white blood cells that come from theblood and that are located in the endometrium in the second phase of
the menstrual cycle and that they will decide: “well this is the momentof the formation of blood vessels” and they lower the guard of the defense against the strangebecausetheembryois50%strange.Thisimmunebalancedependsoninternalandexternal factors and must be worked
on and taken intoaccount.
Untilnow,hehadfocusedmainlyonblooddisorders.Butrightnow,immunologyisalsoverystrong. For example, a woman with autoimmune
hypothyroidism problems can produce that this immune alteration canalterfertility.

BOOK OF ABSTRACTS | 12th European Congress of Integrative Medicine · 1st International Symposium on Integrative Health and Education

Immunological alterations in peripheral blood or endometrium canbe studied.
The problem that usually causes the alterations of the immune system is that either they never get pregnant (even with embryos of very
good quality) or they have recurrent miscarriages.
There are genetic or acquired immunological causes. The acquired
ones can be a hormonal or emotional imbalance.
Because many times the blood does not reach the uterus in a sufficient way and this can be due to:
Because blood is notfluid because the blood vessels are scarce or too
many or too much quality and this has to do with antibodies.
Even in this case even the state of the vaginal flora can affect this immunology.
State of the uterus
For many years fertility has focused on studying the embryo and thequality of the ovum and sperm and everything pointed to a good ovarian response and that there was a good morphologically embryo andthey began to forget that it is not all that is needed. good implantationand then a placental development that keeps the pregnancy.
Andthishasmeantthatalthoughembryosofverygoodqualityareproduced,theydonotimplantor abortions occur and that is why we have to
see what else can bedone.
The uterus is the one that has to allow the passage of the sperm (if we
speak of natural fertility) or allow the implantation of an embryo (if wetalk about assisted fertility).
So in the uterus there are very important data some taken into account in a systematic way as the quality and thickness of the endometrium but others are not so well known. Because if the endometrium is
not well, pregnancy is not achieved.
These other parameters to consider are:Possible vascular or functional functional alterations (uterus in anteversion, retroversion, etc ...) that may be altering the vascularizationand therefore the fetal nutrition. The endometriumis importantinthefirst8-10weeksbecauseitisasourceofbloodandoxygenbecausethereisstillno placentaformed.
Acidificationsthatmaycomefrominflammations(suchasendometriosisorinfections)thatmaybe asymptomatic but prevent implantation oftheembryo Stress, poor diet, environmental pollution, cigarettes, caffeine, or hormonal factors the endometriummaybeoutofsyncwiththegrowthoftheembryoanddonotbecomedyssynchronous and pregnancy
does not occur or recurrent lossesoccur.
All these data must be taken into account when preparing the lastphase that is the preparation of the land so that the embryo can be
implanted
Conclusions
The approacht o fertility problems hastobe very specialized, takingin to account not only the quality of germ cells and the embryo and,moreover, it must be more and more individualized taking into accountthe status of immunological, hormones or field axes. For this there arepoints that have to begin to be included in infertility approaches suchas:
Bad habits and lifestyle that can affect fertility in a profound way:
Stress alters hormonal axes and immunology.
The balanced versus unbalanced diet and this may affect the qualityof ovulation and endometrium. For example: lack of vitamins E and D
that are immunomodulatory. Amount of fatty acids and types of fatsthat modulate the immune system and fluidify theblood.
Excess of caffeine (cola drinks) produce vasocontraction and alter thecirculation of the blood of theendometrium.

33

References
First Births to Older Women Continue toRise.
T.J. Mathews, M.S.; and Brady E. Hamilton, Ph.D. NCHS Data Brief No. 152
May 2014
Molecular characterization of the human microbiome from a reproductive perspective Amir Mor, M.D., Ph.D.,a Paul H. Driggers, Ph.D.,b andJames H. Segars, M.D.b a Department of Obstetrics and Gynecology, Maimonides Medical Center, Brooklyn, New York; and b Department of GynecologyandObstetrics,JohnsHopkinsSchoolofMedicine,Baltimore,Maryland.
Fertility and Sterility® Vol. 104, No. 6, December 20150015-0282
Effect of vaginal probiotic lactobacilli on in vitro–induced sperm lipid peroxidation and its impact on sperm motility andviability.
ArcangeloBarbonetti,M.D.a,b,BenedettaCinque,Ph.D.c, MariaRosariaCaterinaVassallo, Ph.D.a,Salvatore
Mineo,
Ph.D.a Sandro Francavilla, M.D.a, Maria Grazia Cifone, Ph.D.c, Felice Francavilla, M.D.a. Fertility and
Sterility Vol. 95, No. 8, June 30,2011a Division of Maternal-Fetal Medicine and b Department of Obstetrics andGynecology, UniversityofSouth
Carolina– Greenville
School of Medicine, Greenville Health Systems, Greenville, South Carolina.
Fertility and Sterility® Vol. 104, No. 6, December 20150015-0282
5. A strategy to validate a selection of human effect biomarkers using adverse outcome pathways: Proof of concept for phthalates and reproductive
effects.
Kirsten A. Bakena,∗, Nathalie Lambrechtsa, Sylvie Remya, Vicente
Mustielesc, Andrea Rodríguez-Carrillod, Christiana M. Neophytouf, Nicolas Oleac, Greet Schoetersa. Environmental Research 175 (2019)235–256

AFTER OBSTETRIC VIOLENCE. THE
INTEGRATION OF THE AGENCY
Serena Brigidi, Ph.D Medical Anthropology.
Aggregate profesor. Department of Social Sciences and Welfare. Faculty of Health and Welfare Sciences. UVIC-UCC
Research Group on Methodology, Methods, Models and Outcomes of Health and Social Sciences(M3O)“Stories matter. Many stories matter. Storieshavebeenusedtodispossessandculminate,buttheycanalsobeusedtoempowerand humanize. Theycanbreakthedignityofapeople,buttheycanalsorestoreit”.
Chimamanda Ngozi Adichie, 2019:28
Obstetric violence (OV) is a specific form of gender-based violence. OV should be explained from and with a gender perspective.
OV is part of the culture of possession, abuse of power and imposition of gender roles (Brigidi, 2019; Brigidi andFerreiro- Mediante, 2018; Brigidi, 2016a; Lipperini and Murgia, 2013). It is worth
mentioning that the people involved in the OV process are diverse:
woman, baby/s, foetus, partner, etc. during the process of pregnancy, childbirth and upbringing, health professionals and, in ethical and political terms, the society in which we live (What value
do we attribute to maternity/paternity?).Intheprocessofpregnancy,childbirthandpostpartum,numerous violent manifestations andrepeated disrespect, presence and reciprocity on the part of health professionals are observed. In fact, we consider OV not only ex-

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BOOK OF ABSTRACTS | 12th European Congress of Integrative Medicine · 1st International Symposium on Integrative Health and Education

cessive interventionism, but also the omission of assistance. Thus,
we speak of OV, without exhaustive character, when in the processof pregnancy, childbirth and postpartum: 1) Thereisdehumanizedtreatment.2)Inappropriate,rudeorpaternalisticlanguageisused.
3) Discrimination is made by social class, ethnicity, nationality,
sexual orientation, etc. 4) Humiliation, ridicule and criticism are inflicted. 5) Information is omitted or hidden, thus interfering with awoman’s decision-making power and her right to autonomy over
her own health. 6) Women’s right to privacy is violated. We also
speak of OV because of the worrying rates of episiotomies (Vv.
Aa, 2010; WHO, 1985); because of the frequent performance ofKristeller’s manoeuvre (Brigidi, Cardús and Ausona, 2014; EPEN,
2014) andbecauseofthehighnumberofcaesareansectionsperformedintheIberianPeninsula (DONA LLUM, 2018). The data produced by the Observatories on Obstetric Violence are extremely worrying. (OVO, 2016; Droits Humains et Femmes Enceintes, 2016).
We highlight some of the main sequels in OV for women: major
depressions, PTSD, PTSD, tocophobia,dissatisfaction,frustrationandangeraboutthecarereceivedbefore,during and after childbirth,
distrust of the health system, low rates of success in breastfeeding, problems with the bonding and upbringing of babies, conditioning of their subsequent reproductivelife(OVO,2016;EPEN,Olza,2013;Landyetal.,2011).Adverseeffectsafter episiotomy: 3rd and4th degree tearing; anal sphincter dysfunction after childbirth; dyspareunia. Some of the risks to mothers after Kristeller’s maneuver:
bleeding and contusions;uterineruptureanduterineinversion,whichcanleadtoseverebleedingand, in extreme cases, result in removal of the uterus; increased risk of 3-4 fourth degree, perineal andvaginal tears; urogenital prolapse; premature detachment of theplacenta; ribfracture;contusions.Forinfants:increasedlikelihoodofshoulderdystocia;brain trauma; sternocleidomastoid muscle tear;
Erb’s palsy; rib fracture; hypoxia; internal organ lesions; increased
intracranial pressure, cephalohematoma, intracranial hemorrhages (EPEN, 2013).
To affirm that the process of pregnancy, childbirth and upbringing, as well as obstetric violence, are related to gender is to reflect on the meanings and signifiers that we attributetothem,totheimageofthem(p)aternity,mothers,fathers,families,andofthe
healthprofessionalsthatweexpect,desireorbuildinoursocieties(Brigidi,2016b).Thus, childbirth, for example, in the dominant discourse, turns out to be a product, a finished act, and is not thoughtof or studied as an experience, a process of transformation. The
forms of infantilization of women, the use of paternalistic, violent
or denigrating verbal communication,theabsenceofadialoguecenteredonreciprocityandrespect,theways in which the positionof women and their companions is weakened or the comforts orinterests of other people are privileged, are products of a historical and cultural process that cannot be understood or changed
without a genderperspective.
Obstetric violence has nothing to do with gender because it is
women who experience it withtheirbodies,becausethiswouldmeanthinkingofgenderasademographicvariable or a biological category. By qualifying it as gender-based violence we are referring
tothe models with which we socialize, learn, define, give values
and meanings to pregnancy, childbirth and upbringing, and to violence within a historical and cultural framework. These expose us
to a greater lack of security. We think, for example, of: 1) ) the lackof co-education in most of the political and pedagogical arguments
about equity and equalityinupbringing,2)howbiomedicalandpopulardiscoursesareconstructedaround protection and risk behavioursin pregnancy or childbirth (Brigidi, 2016a), 3) representations offamily care and self-care, the use of drugs during pregnancy andbreastfeeding.
In the same way we reflect on the working conditions of pregnant women and mothers and their consistency in terms of health:unemployment, temporality, precariousness, dependence until weobserve an ever more consistent presence of maternal mobbing
and opting out. These phenomena, in addition to being related toworkplace violence, put women’s stability at risk, as well as their
possibilities for autonomy and empowerment. Frequently these
aspects are also related to situations of violence and inequality inaccess to health resources, but also in the management, transmission and creation of knowledge: the limited health research thatincorporates the gender perspective, the studies that take into
account scientific evidence not as a mere form of consentandtheaccessofwomentopositionsofpowerintheAcademyandintheClinic,
for example. A violence to which health personnel are not immune
either. Formed in a hegemonic and endogamic biomedical system,
it builds power relations from the university stage, in which little
is questioned, explored or observed. It perseveres in dual reality,
but social reality is complex and mutant. We are not thinking or
working with uniform or universal categories, and the diachronicand synchronic context mark and determine meanings. Then our
objective would be to introduce analytical strategies and provide a perspective with which to overcome the limitations of the
oppositional schemes-culturevsbiology,masculinevsfeminine,perfectmothervsbadmother,home birth vs hospital birth. We need agender perspective in order to improve attention to the process ofpregnancy, childbirth and upbringing and to make obstetric violence visible, in order to rethink, redefine and resignify this process
based on a critical and situated thought, transforming ourselves as
people and as healthprofessionals.
Understanding the process of pregnancy, childbirth and upbringing necessarily requires using a perspective centred on diversity. This is understood at the level of diversity of users and healthprofessionals, as well as of the dynamics present in this process.
In this sense, we highlight as an element the intersetionality ofgender that has to do with the diversity of social, economic, ethnic and language classes, among others. This intersetionality inthe case of obstetric violence is paradoxical: if on the one hand it
is a global phenomenon, it manifests itself with greater brutality
when the woman does not dominate the language, comes fromanother country, has another religion, etc. In this case the Alterity has been transformed many times in a greater brutality of thewelfare practice. However, the purpose of this work is to highlight the capacity of agency after situations of obstetric violence,
to be able to guarantee diversity in thediscourses (biomedical andpopular), to contemplate what the way of telling the story of violence, who tells it, how and when it has an important impact in
the formation and imaginary of thepeople,tobeabletoconstructrelationsofexchangesbetweenthesubjectsinvolved intheprocess.Inotherwords,tothinkoftheagencyafterasituationofviolenceimplies
tospeakofpower,nottoturnitintothe”definitivehistoryofthatperson”(NgoziAdichie, 2019: 19). We know that in the last five years,
the world of associations linked to sexual- reproductive health andthose of gender violence, the issue of OV has become a central
issue.Inaddition,internationalOVresearchprojectsareontheincreaseintheacademic world and there is an ever-increasing need forspecific OV competence on the part of health professionals. As
an example, many of the medical student associations in Catalo-

BOOK OF ABSTRACTS | 12th European Congress of Integrative Medicine · 1st International Symposium on Integrative Health and Education

nia request extra-curricular training in OV every year, and there
has been an increaseintheworkofTFG(workendofdegree)andTFM(workendofmaster’sdegree) in health sciences on the subjectof OV. However, the concern that emerges from this wave of media and academic interest is that it can concretely respond to thereal needs of future health professionals and women, as well as
being able to guarantee the use of diversifiednarration(itisnotthesametospeakofagypsywomanasofalesbian,ofacis thatofatranswoman)toprovideagency,diversification,power,dignityandhumanityinhealth care and in narration, experience and transgenerationaltransmission of possibilities.
References:
Brigidi Serena (2018) “Sin educar en la consciencia corporal, ¿cómo
vamos a disfrutar del parto?” https://www.elsaltodiario.com/parto/serena-brigidi-disfrutar-parto#, 2018a
Brigidi, S. (2016a) Haec ornamenta sunt mea. Reflexiones en torno al universo (in)material de la maternidad. Femeris, 1: 148-165. 2016
Brigidi, S. (2016b) “Observaciones audiovisuales referentes a los significados de prevención, seguridad, riesgo y (re)presión en el embarazo y parto, periferias, fronteras y diálogos”, en Actas del XIII Congreso de Antropología de la Federación de Asociaciones de Antropología del Estado Español,
Publicaciones URV, Tarragona, Editors: URV, pp.4239- 4249. 2015.
Brigidi, S. (2018). “Jugamos a parir?”. El pošlost’ de la violencia entre brutalidad y trivialidad. En
M. Boladeras Cucurella y J. Goberna Tricas (eds.) El concepto Violencia
Obstétrica y el debate actual sobre la atención al nacimiento. Madrid: Tecnos, pp.161-173.
Brigidi, S. (2019). Las palabras previas a la violencia obstétrica. Prólogo.
En Vv.AA. Miradas a la violencia obstétrica. Pp. 5-8. Barcelona: Pol·len.
Brigidi, S. y Busquets-Gallego, M. (2019). Interseccionalidades de género
y violencias obstétricas.
Revisa Musas, vol4(2), pp. 77-97.
Brigidi, Serena y Ferrero-Mediante, Susana. El observatorio de la violencia obstétrica en España: justificación y trayectoria. mujeres y salud, 42,
pp.18-22, 2018.
Brigidi, Serena; Cardús, Laura y Ausonia, Marta. Entrevista a Beverly
Beech. Àgora d’Infermeria 18 (4): 40. 2014
Butler, Judith. Cuerpos que importan. Barcelona: Paídos. 2002.
Cavarero Adriana. Orrorismo ovvero della violenza sull’inerme. Milano:
Feltrinelli, 2007. Cavarero, A. (2013). Inclinazioni. Critica delle rettitudine. Milano: Raffaello Cortina Editore. CokerAnnL,Cook-Craig,PatriciaG.,CorrineM.
Williams,etall.EvaluationofGreenDot:An
Active Bystander Intervention to Reduce Sexual Violence on College
Campuses Violence Against Women, 13, pp. 129-145. 2011
DONALLUM-AssociacióCatalanaperunPartRespectat.InformeNacerenhorariolaboral2018.DONA LLUM ASSOCIACIÓ CATALANA PER UN PART RESPECTAT. Informe neixer en horari laboral.[enlínea].
[Consulta:
4 dediciembre de2018].
Disponible en:https://www.donallum.org/blog/informe-neixer-en-horari-laboral/
Droits Humains et Femmes Enceintes. First Congress in Obstetric Violence. Pau, France, 2016. Foucault Michel. El nacimiento de la clínica. Madrid:
Siglo Veintiuno.2007.
GOBERNA TRICAS JOSEFINA y BOLADERAS CUCURELLA MARGARITA(Coord.) El concepto
Violencia Obstétrica y el debate actual sobre la atención al nacimiento.
Madrid: Tecnos, 2018. pp.161-173.
Green, Lawrence “From research to “best practices” in other settingsand populations”, de la revista American Journal of Health Behavior, vol.
25/n. 3, p. 165-178.

35

JULIANO DOLORES. Tomar la palabra. Mujeres, discursos y silencios. Barcelona: Bellaterra, 2017. Lipperini, Loredana y Murgia, Michela. L’ho uccisa
perché l’amavo. Falso! Roma: Laterza, 2013. Olza, Ibone; Ruíz, Lola. Traumatic Childbirth Affect the professionals? Bilbao: Congreso FAME,2014.
OVO. Relatos de mujeres recogidos en el Informe del 25 de noviembrede 2016.
SADLER MICHELLE et al. Moving beyond disrespect and abuse: Addressing the structural dimensions of obstetric violence. En: Reproductive HealthMatters, vol. 24, núm. 47, pp.47-45
Vv.Aa. European Perinatal Health Report . Europeristat. 2010 WHO. Declaración de Fortaleza. 1985

NON-CONVENTIONAL THERAPIES INWOMEN WITH BREAST CANCER AND
ITS RELATION WITH CONVENTIONAL
THERAPIES.
Valeria Santoro Lamelas1, Eva Garrido2, Margarida Pla2, Rafael Manzanera3, Xavier Bargalló4,
Rosa Puigpinós-Riera5
1UniversitatdeBarcelona.Dep.dePsicologiaSocial2UniiPsicologiaQuantitativaFac.dePsicologia,
versitat de Barcelona. Departament d’Infermeria
de Salut Pública, Salut Mental i Maternoinfantil ,3Health and Economic Benefits Area, MC Mutual,
Barcelona, Spain , 4Hospital ClínicdeBarcelona.
Breastradiologyunit.5UniversitatdeBarcelona,Serveid’AvaluacióiMètodes d’Intervenció, Agència de Salut Pública de Barcelona, Barcelona,Spain

The use both Non-Conventional Therapies (NCT) have become ausual strategy that people use to squire the treatment process andto reduce its side effects [1] [2]. In that sense,theinterestofNCThasgrowninwomenwithbreastcancerasatooltominimizing the impact ofconventional treatments and fostering a healthier lifestyle [3][4].
Aiming to understand the different uses of NCT in women diagnosed on breast cancer from the public network of hospitals in Barcelona. As well as, reflect about its socialand material determinants. We
have developed a mixed methods study in a cohort of 2,235 women.
Itconsistofaquantitativeandqualitativesub-studies.Bothstudiescomplement each other and allow us to obtain a precise and complex image about the use of non- conventionaltherapiesinwomenwithbreastcancerwithinthenetworkofpublichospitals in Barcelona. Including thenarrations of women that have or had had breast cancer, allow us to
put on the centre the experiences, arguments and feeling of women.
Giving to women more visibility as an important agent in the problematization of the use of the NCT.
Specifically, we analyze the processes and sources of informationthat the users use, thetypesofcombinationoftheNCT, thecredibilityofthesourcesusedbytheusers,the multimodality in the use, the moments of the process associated with the type of use, the possibilitiesof the use of NCTs according to economic and socialconditions.
We highlight five main areas: a) Uses of the NCT; b) Reasons for the

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BOOK OF ABSTRACTS | 12th European Congress of Integrative Medicine · 1st International Symposium on Integrative Health and Education

use of NCTs; c) articulationoftheNCTwiththehealthsystem;d)RisksofanunregulatedNCT;e)Social determinants and theNCT.
Uses of the NCT: We have shown high use of non-conventional
therapies that coexist with conventional therapies in the treatment ofbreast cancer: more than half of the women surveyed claim to haveused unconventional therapies in the treatmentprocess.Beingthemostusualtherapiesnaturopaths,homeopathsand herbalists (31.2%,
30.9% and 30.5%respectively).
Reasons for the use of NCTs: the reasons for using non-conventional therapies arelinkedtoself-carepractices,understoodasstrategiesavailabletotheperson with the intention of improving their health and/or quality of life, reducingthe impact physical and psychological aspects of cancer and its treatment. Other cases link the use of NCT as aprocess of personal change where the person placetheirselfasthecentreoftheirownlifeandvaluetheenjoymentineveryday life.
Likewise, the inclusion of NCT in the treatment of breast cancer
works as a strategytoshareprocesseswithwomenwhoareatsimilarsituations,asamutual helpgroup.
The NCTs and thehealth system: On the one hand, women participants show a great openness around NCT practices, since hospitals
and Associations offer them.
44.0% and 34, 8% of women stated that their oncologist and family
doctor respectively was informed about the use of NCTs the women,with 44.4% and 33,6% of them indicating that their oncologist andfamily doctor respectively advised against their use or did not showmuch interest in knowing exactly what the therapies consisted of.
These two groups of practitioners were those with whom the women claimed to speak more openly about the NCTs they were using,followed by pharmacists. The women also affirmed that those practitioners who showed an interest and were open to consultation alsotended to be well-informed and intervene in situations of possible
incompatibility
Some subjects took a twofold therapeutic approach, with “alternative oncologists”,astheythemselvesdefinedthem,andhospitaloncologists.Inthese cases they assumed that it was preferable not to give information to the latter. Even other health practitioners advised them
to follow the two pathsseparately.
Risks of an unregulated NCT: Another element to be highlighted isthat women sometimes use of NCT without any clear evidence-based reference, neither any problematizationaboutpossibleadverseeffectswithtraditionaltreatment.Thisis opposedbyargumentslinkedtoanexcessofmercantilizationofthesector,which potentialities in thepresence of professionals and techniques of doubtfulutility.
Social Determinants and the NCT: One important element is the social differences in the access to information and use of NCT. Womenfrom high and middle social-economic groups reported seeing practitioners at private clinics. Also,theyweremuchmoreinformedabouttheproductsandmuchmorecapable of following integrative strategies.
Low social class groups reported using more public health system
resources and herbal products. In this sense, we can assume that in
our study, social inequalities [5] [6][7] are materialized in greater limitations in the access to NCTs and knowledge about their use andscope of low social class groups. That is why it becomes imperative topromote the development of public policies aimed at increasing equitable access to NCT knowledge and products of proven effectivenesswhile preventing potential misuse or pernicious use of theNCT.
Conclusions: Based on the results, we emphasize the paper that
non-conventional
therapiesacquireasacomplementtoconventionaltherapiesinthetreatmentofcancer. These offer diverse resources

to face breast cancer and its treatment. However, the presence ofmultiple therapies, often unknown by patients and health personnel
make it difficult to discern who uses it, its effectiveness. It is in thissense that the knowledge of suchtherapiesbythehealthsystem,allowsadviceandguidanceinitsuseandpossible interactions with traditional
therapies. On the contrary, the closing of the health system to them
derives to the women who use such therapies look for evidences fromoutside thesanitarysystemandwithoutguaranteesofitseffectiveness.
Also,itderivesthatsome womenchoosenottotellhealthpractitionerstheiruseandinextremecases,toabandon conventional therapy. Thoseelements show an important call to professional and institutional integration forwards a person-centeredtreatment.
Likewise, the lack of regulation and public coverage of most
non-conventional therapies results in their use being strongly linked
to social class. Being the medium-high social class sectors who benefit
from their potentials. This element increases the inequalities in health and quality of life of women with breast cancer due to their social
condition. In this sense, traditional and no traditional therapist must
to be reflexive about the social stratification on health and well-beingthat reproduce the inequalities of economic and social capital in theservices that professionals offer. And in special, working together toreduce health and well-being inequities.

References
Harris PE, Cooper KL, Relton C, Thomas KJ. (2012) Prevalence of complementary and alternative medicine (CAM) use by the general population: asystematic review and update. Int J Clin Pract; 66:924– 39.
Bahall M (2017) Prevalence, patterns, and perceived value of complementary and alternative medicine among cancer patients: a cross-sectional,
descriptive study. BMC Complementary and Alternative Medicine:17:345
YatesJS,MustianKM,MorrowGR,GilliesLJ, PadmanabanD,AtkinsJN,IsselB,KirshnerJJ,Colman Lk (2005) Prevalence of complementary and alternative medicine use in cancer patients during treatment. Support Care Cancer.
13:806–11.
Boon HS, Olatunde F, Zick SM (2007) Trends in complementary/alternative medicine use by breast cancer survivors: comparing survey data from1998 and 2005. BMC Womens Health.7:4-6
Benach, J y Muntaner, C (2005) Aprender a mirar la salud ¿Cómo la desigualdad social daña nuestra salud? Barcelona Viejo Topo
Borrell, C y Artazcoz, L. (2008) Las políticas para disminuir las desigualdades en Salud. Gaceta Sanitaria; 22 (5)465-73
Martínez García, JS (2013) Estructura social y desigualdad en España.
Libros de la Catarata,Madrid.

SYSTEMATIC REVIEWS AND METAANALYSIS OF COMPLEMENTARY
THERAPIES IN ONCOLOGY.
Dr. Sergio Abanades. Instituto de Salud Integrativa y Consciente, Barcelona
Introduction
The use of complementary therapies in oncology has dramaticallyincreased during the last years. However, the level of scientific evidence in this area is uncertain and still face important controversies.

BOOK OF ABSTRACTS | 12th European Congress of Integrative Medicine · 1st International Symposium on Integrative Health and Education

Methodology
A data analysis and extraction of evidence and recommendations by levels of evidence from the “Clinical practice guidelines
based on systematic reviews of the literature” of the “Society ofIntegrative Oncology” was performed. Additional search was expanded in Pubmed limited to: “systematic reviews” “meta-analysis” up to September 2018.
Results
Evidence-based clinical practice guidelines recommend acupuncture for poorly controlled pain and post chemotherapy nausea and vomiting (1A) and xerostomia (1B). In the managementof the stress of the oncological patient “Mind and body techniques” through a multidisciplinary approach are recommended toreduce anxiety, mood disorders, pain and increase quality of life(1A). Regarding the additional search for systematic reviews andmeta- analyzes up to 2018: There is evidence of the highest levelthat comes from systematic reviews and meta-analysis of randomized and controlled clinical trials for:-Acupuncture: post-chemotherapy nausea and vomiting, xerostomia, pain and fatigue and arthralgia for aromatase inhibitors in breast cancer-Mindfulness/meditation: stress, anxiety, mood disorders, pain
and quality of life
-Yoga: fatigue, stress, anxiety, mood disorders, pain and qualityof life-Probiotics: diarrhoea during chemotherapy/RT, intestinal barrier maintenance, prevention of postoperative infection-Vitamin D: infra-therapeutic levels vitamin D associated withdecreased survival (breast and lung cancer)-Vitamin E topical: oral mucositis after radiotherapy and/ or
chemotherapy-L-Glutamine: mucositis post RT / chemotherapy and decreases stay and infectious complications in enteral nutrition-Reishi Ganoderma lucidum: Improves immunity as a complement to chemotherapy / RT
-Omega-3 fatty acids: ensure weight maintenance in enteralnutrition
Conclusions and evidence-based recommendations-Thereareseveralcomplementarytherapieswithevidenceofefficacyandsafety derived from meta-analysis inoncology.
-Complementary therapies with the highest level of evidence
should be incorporated into the integrated treatment of cancer
patients.
-Information should be provided (based on scientific evidence)
to facilitate the training of the oncology team to promote an integral treatment of the cancer patient.

INTEGRAL MANAGEMENT OF THE
PATIENT WITH CANCERAUTHORS: JAVIER ESPINOSA ARRANZ -MD, PhD(1) AND JOSÉ CARLOS VILLA GUZMÁN –MD: Head of medical oncology, Ciudad Real General
University Hospital, Ciudad Real, Spain.
: Medical assistant, Oncology Service, Ciudad Real
GeneralUniversity Hospital, Ciudad Real,Spain.

37

ABSTRACT.Cancer is more than a disease, but a set of diseases. It´s all thespheres of the human being that are sick. Since the moment of
diagnostic and for some years, sometimes for many years or thewhole life, patients are treated for their disease rather than theindividuals they were before.
The Health system should be sensitive enough to detect all
the needs of the patient and assist them. Integrative oncology is
about understanding the whole body. It is very important to consider aspects such as maintain a healthy diet, do regular exercise
and be physically active as well as maintain an adequate psychological state. These are only some of the aspects we must try toempower.
Key words: integral management, cancer, oncology
REPORT.Introduction.Cancer is more than a disease, but a set of diseases. It affects
all spheres of the human being: mind, body, and spirit. Cultural,social, family, sexual, and personal relationships aspects must be
taken into account.
Integrative medicine denotes a total approach to medical carethat combines conventional medicine with the complementary/alternative approaches shown to be safe and effective. the complementary term is more appropriate, because conventional medicine is essential today in management of most tumors.
With studies showing that around half of all cancer patientsuse therapies that are not part of mainstream medicine (surgery,chemotherapy, radiotherapy and conventional supportive care),a debate arises between supporters and detractors of integrative
medicine (1).
The reasons why patients make use of integrative medicine inOncology, are diverse: to improve symptoms of disease, decrease side effects of treatments, support emotional health, boost
the immune system and ultimately improve their quality of life.
Breast cancer patients are particularly inclined to use integrative
medicine, and many times they do not tell their doctors. It is avery important handicap because many “natural” treatments interfere with chemotherapy and modern molecules.
Patients often manifest that integrative medicine helps themto improve quality of life and possibly the length of life, find peace with the diagnosis, remove stress, understand their disease,handle fatigue due to treatments, and face diagnostic tests andreviews (2).
Many patients also search web pages to consult about theirdisease, novel treatments and patient forus.
It’s doctor’s obligation to recommend reliable web pages to patients.
Integrative medicine is a combination of medical treatments
for cancer and complementary therapies to face symptoms andside effects. It is interdisciplinary, combining the skills of different
health-care specialists, attending all the spheres of the humanbeing.
On the other hand, due to early detection campaigns and medical advances, the number of cancer survivors continues to riseday by day. Fatigue, pain, fear of recurrence, and stress are longterm sequelae. Many patients show interest in integrative medicine modalities for prevention of recurrence, optimizing health,enhancing quality of life, and managing symptoms (3).
Dietary habits, physical activity, supplements, relaxation tech-

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BOOK OF ABSTRACTS | 12th European Congress of Integrative Medicine · 1st International Symposium on Integrative Health and Educationniques, acupuncture, and other techniques such as meditationand massage, may play a role in the management of the physicaland emotional aspects faced by cancer survivors.
Objectives of integrative oncology.As it was mentioned above, cultural, social, family, sexual, andpersonal relationships aspects must be taken into account when
we face a patient with cancer. The news of the diagnosis implies
the most drastic change in a person’s life. Body, mind and spirit
feel threatened and all patient´s pillars collapse. Main symptoms
are “total” pain, anxiety / depression, insecurities...
The psychological support, some dietary advice and tips onwhich web pages to consult are some of the actions in this phase.
In the treatment phase, patients need to improve symptoms
related to their disease and reduce side effects of cancer treatments. A proper diet, regular exercise and strengthen their psychological defenses are the main aspects we must address. We
must help them find peace with the diagnosis, remove stress,
understand their disease, handle fatigue due to treatments andimprove their quality of life. Many patients need to consult other
opinions. We should advise what reliable web pages should
check.
After the treatment phase, fatigue, pain, fear of recurrence,stress are long-term sequelae. In this phase these are main aspects we must help the patient to face, and some web pages andforums may reduce stress.
Integrative medicine can contribute for prevention of recurrence, optimizing health, enhancing quality of life, and managing
symptoms
In summary, we should improve patients´quality of life. In allphases, despite the oncologist, in the disciplinary team, someother specialists must participate: a dietitian, a psychologist, aspecialist in naturopathy
and a rehabilitator.
Finally, prevention of cancer should be part of our job as doctors and caregivers. We should contribute to prevention campaigns. We should raise prevention programs in which food should be
one of the most relevant issues. Chemoprophylaxis either withchemical or natural products should also be approached from thepoint of view of integrative medicine.
Integrative management of cancer patient.- Diet.Many references to diet have appeared last years. There is no general advice and it must be adapted to each specific case. A dietitian may help the patient in each phase. In the treatment phase, forexample, yogurt and cheese instead of milk may be adequate, but ofcourse milk is not contraindicated.
Much has been reported about sugar and cancer. The patient
should reduce it to the minimum and replace it with Stevia for example. The patient must avoid food with dyes and excessive salt. Fresh
and frozen food is recommended.
Some coffee may be beneficial.
With respect to carbohydrates, cereals and cookies are appropriate.
Bread, rice and pasta must be part of a good diet for cancer patients.
With regard to vegetables, potato, clabaci, onion, garlic and carrot
are suitable.
The patient must eat meat: chicken, turkey or rabbit are someexamples. White fish such as hake, sole, grouper, rooster, monkfish,sea bream, turbot and conger are recommended.
With respect to dairy products, fresh cheese, cooked eggs, omelette and bechamel are adequeate.
Some desserts such as yogurt, flan custard, curd, ice cream, smoothie, sorbet and fresh fruits such as banana, strawberries are someexamples. It is very important to maintain an abundant hydration for
all the treatment.
Roiboos is a medicinal plant that may be very suitable. Some depurative plants such as chicory, artichoke and Marian thistle may be
useful during this phase (4)(5)(6).
Exercise.The feeling of being constantly tired is very often in cancer andduring chemotherapy. In order to maintain high energy levels it isimportant to expend time relaxing and doing simple and feasible
things. Some suggestions we make to our patients are: going for awalk with a friend, doing some gardening work, dancing, rewarding
themselves and ensure a rest.
Working during cancer treatment is feasible, and in some cases,
advisable. Patients must talk openly about it with their boss. It is
important to have enough rest times, flexible day, privacy and confidentiality and request the necessary aid (7).
Facing stress and fear.Fears of cancer emanates from a view that cancer is considered
an unbeatable enemy; some patients think that there are few strategies to fight and they fear social implications of succumbing, anddying from cancer.
We must consider the psychological aspects and face them with a
psychological support. All patients in the different phases should be
supported by a psychologist (8).
We are working in Ciudad Real on a project to transfer care to
primary care. In the future, we will have an unit of large-survivors.
Other issues.The use of complementary techniques help patients to face fatigue, fears, stress… improve their immunity and their quality of life.
Some of the used techniques are (9): https://medlineplus.gov/
ency/patientinstructions/000932.htm. Integrative medicine for cancer treatment
Acupuncture. This practice may help patients to relieve nausea
and vomiting. It also may help them to decrease cancer pain andhotflashes.
Aromatherapy. this treatment based on fragrant oils may improvehealth or mood. It also may help relieve pain, nausea, stress, anddepression.
Massage therapy. This type of body-work may help to relieve
anxiety, nausea, pain, anddepression.
Meditation. Practicing meditation may relieve anxiety, fatigue,
stress, and insomnia.
Ginger. This herb may help reduce the nausea of cancertreatments.
Yoga. This mind-body practice may help relieve stress, anxiety,and depression (10).
Conclusions.Cancer patients face their disease with fear, stress and as a life
threatening situation. Many problems arise concerning feeding,activity, psychology... and all the spheres of the human being are
involved. Our purpose as physiciansand caregivers, is to face new

BOOK OF ABSTRACTS | 12th European Congress of Integrative Medicine · 1st International Symposium on Integrative Health and Education

challenges together with our patients, regarding their body, theirmind and their spirit.

Bibliography.1.- Alberto Costa. Complementary and integrative medicine for cancer
patients A purely ideological debate? May / July 2017 Cancer World.
2.- Mailman J. A Patients’ Perspective on Integrative Oncology: Getting
Past the “War,” Living With and Beyond. Cancer, J Natl Cancer Inst Monogr
2014;49:291 3.- Viscuse PV, Price K, Millstine D, Bhagra A, Bauer B, Ruddy
KJ. Integrative Medicine in Cancer Survivors. Curr Opin Oncol. 2017;29:235–
242.
4.- Farvid MS, Malekshah AF, Pourshams A, et al. Dairy food intake andall- cause, cardiovascular disease, and cáncer mortality. Am J Epidemiol
2016;DOI:10.1093/aje/kww/139.
5.- http://www.mskcc.org/cancer-care/integrative-medicine.
6.- www.oncosaludable.es.
7.- cuidar en Oncología, SEOM, www.seom.org.
8.- Vrinten C, McGregor LM, Heinrich M, von Wagner C, Waller J, Wardle
J, Black GB. What do people fear about cancer? A systematic review andmeta-synthesis of cancer fears in the general population. Psycho-Oncology.
2017;26:1070–1079.
9.- https://medlineplus.gov/ency/patientinstructions/000932.htm. Integrative medicine for cancer treatment.
10.- Greenlee H, Balneaves LG, Carlson LE, et al; Society for Integrative
Oncology. Clinical practice guidelines on the use of integrative therapies as
supportive care in patients treated for breast cancer. J Natl Cancer Inst Monogr. 2014;50:346-358.

MAKE LOVE NOT WAR: AN INTEGRALVISION OF CANCER.
Dr. Tomás Álvaro Naranjo. Specialist and PhD
in Pathological Anatomy in the study of cancer
differentiation. Integral Health Center Arjuna
Tortosa. Hospital Verge de la Cinta, Tortosa(Tarragona/España)

In 1947, one hundred years after Virchow’s contributions,
Farber proposed a metabolic treatment with folic acid forchildren with acute leukaemia, which proved disastrous.
He did not give up, and he proposed exactly the opposite
manoeuvre,theuseofafolicacidantagonist,aminopterin.Thistimehewasright,andforthefirsttimeeverheshowed that haematological remission of leukaemia was possible. This treatment made him the father of clinical chemotherapy. It was ofparticular significance at a time when the surgeons of the era,with Halsted and his radical approachtocancer,wereforcedtoacceptthatthebattlewaslostinspiteoftheirtitanicefforts.
Itwashardtoaccept
thattherewasaprofoundconceptualerror:cancerwasnotalocaldisease,butratherasystemicdisease.
Ittook tens ofthousandsofbreastamputationstoacceptthatifthetumourisconfined,localsurgerywillsuffice,butifthetumour hasalreadyspread,surgery,nomatterhowaggressive,willbeuseless.Theconclusionthatasystemicdiseasedemands asystemic cure completely changed theparadigm.
Chemical therapy, i.e. chemotherapy, was thus revealed
as the great promise, although with important side effects,
which were considered less important than the drug’s sou-39

ght-after efficacy, something that continues to this day. Unfortunately,mostoftheevidenceindicatesthatthetoxicregimenonlyproducesamarginalbeneficialeffectinmost patients, atbest a modest increase in survival, something far from being
a cure. With better and improved drugs, the totalcontributionofcurativeandadjuvantcytotoxicchemotherapybarelyexceeds2%inimprovingsurvivalat5years among the 22 mostcommon neoplasms in adults (1). With the latest and mostadvanced progresses, the effect on overall survival of theseveral dozen drugs approved by the FDA and the EMA in
recent years does not reach the 2.5 months established by
ASCO and ESMO as a minimum “clinically significant” effect(two). In the worst case, the chemotherapeutic regimen may
contribute to the spread of the disease(3).
It is as if medical science had received a call to battle thathas taken us from the radical surgery room to the radical
chemotherapy room, with its consequences of morbidity,
human suffering and economic unsustainability. The empirical discovery of chemotherapeutic agents has been shownto disappoint while genetic cancer treatment, once a great
promise, usually does not go beyond the headlines. Today,
the cure for cancer is beyond human knowledge and technology. Progress in the war on cancer shows around a 2%
improvement in survival or a few months with immunotherapy as tangible clinical achievements. The study of molecular defects has led to successful targeted therapies for somecancer groups, but has not been able to change the generalcourse of the disease (4). Throughout the history of knowledge, the one cause-one cure approach has not worked.
In light of the results, it may now be necessary to consider solving the fundamental biological enigmas of cancer, tobetter understand tumour cells, their environment and theirecosystem, the genetic and epigenetic, metabolic, relational,
and bioelectrical aspects, the fields of information and thelanguage of tumours. After many years focused onthewarontumourcellsasadiagnosticandtreatmentcentre(chemotherapy,radiationtherapy,surgery),perhaps the time has come toexpand the focus: the tumour microenvironment, its vessels,
the stroma, the immune system, metabolism, bioelectricity... and also the microbiota, mechanotransduction and the
hypothalamus. We also need to focus on the patient’s life
circumstances, stress, fear, suffering, theirhistory...
Experimental data strongly show that normal cells and tumour cells are context-dependent and that mutations cancause cancer and vice versa. The phenotypic heterogeneity and a complete network of gene regulation in relation
to themicroenvironmentshowtheepigeneticcharacteroftumourcellsasaproblemofreprogramming.Thisalsoimplies thatthe neoplastic phenotype can return tonormal.
1 Tumour cells continue to maintain receptivity to a large
number of non-cytotoxic, hormonal, immunological, stromal, metabolic and many other stimuli, capable of setting
in motion epigenetic programs to differentiate and control
the proliferation and revert the malignant phenotype. Redefining victory implies incorporating a systemic vision,
where the next steps for science in the study and integral
treatment could consider cancer as a metabolic disorder;
the mitochondria,thedamagedengineofthetumourcell;themicrobiota,thearchitectofthematurationoftheimmune sys-

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BOOK OF ABSTRACTS | 12th European Congress of Integrative Medicine · 1st International Symposium on Integrative Health and Education

tem, the structure and function of the tumour ecosystem andthe response to chemo- and immunotherapeutic treatment; themind and the field of neuroimmunology, as the master regulatorof physiological and oncogenic homeostatic equilibrium; and themicroenvironment, the maker of a universe of structures, functions and relationships,withoutwhichitisimpossibletoconceptualisethediseasethatwestillcall”cancer”today.Theproposal consistsof a bottom-up approach, which allows us to understand normal
and tumour biology, so that we can create friendly and non-toxic
prevention and treatment plans. That is, we need to make loveand not war to the tumour cell and tissue within its own system,
the person who hasit.
1.- Morgan G, Ward R, Barton M. The contribution of cytotoxic
chemotherapy to 5-year survival in adult malignancies. Clin Oncol (R Coll Radiol). 2004;16:549-60.
2.-DreicerJJ,MailankodyS,FahkrejahaniF,PrasadV.Clinicallymeaningfulbenefit:realworldusecomparedagainsttheAmericanandEuropean guidelines. Blood Cancer J. 2017;7:645.
3.- Karagiannis GS, Condeelis JS, Oktay MH. Chemotherapy-induced metastasis in breast cancer. Oncotarget. 2017;8:110733110734.
4.- Kumar H, Fojo T, Mailankody S. An Appraisal of Clinically
Meaningful Outcomes Guidelines for Oncology Clinical Trials.
JAMA Oncol.2016;2:1238-40.

HOW CAN WE INTEGRATE ANINTEGRATIVE MEDICINE DIVISION IN A
HOSPITAL?
Pere Gascón, Servei d´Oncologia Mèdica Hospital
Clínic, Universitat de Barcelona, Barcelona
While the use of Integrative Medicine in the United States wasmade official by the federal government in the 1990s with thecreation of the National Center for Alternative/Complementary
Medicine (NCACM), recently renamed the National Center for
Integrative Medicine (NCIM), in Spain these are difficult times
since the Ministry of HealthandMedicalAssociationshaveanegativeattitudetowardseverythingthatisnot allopathic medicine.
There are attempts in several Spanish hospitals to create an
IntegrativeMedicineUnit,buttheyaresporadicattemptsthathavesometimesclashed with the management’s prejudice. With afuture-oriented outlook, one could consider adding acupuncture in the pain units, incorporating the use of certain medicinal
plants andfungusextractstotheNutritionServicesinourhospitalsor,withacertainoptimism, onecouldhopethatalltheseaspectscanconvergewithintheSupportTreatmentUnits of the respective
hospitals. The current importance of intestinal microbiota in allareas ofmedicinewillpossiblyforceIntegrativeMedicinetobeintroducedintocertainpublic hospital services. The lack of a budget tohire expert professionals in different facets of Integrative Medicine will make it grow and establish Integrative Medicine Units
and Divisions in the private field. This fact is already happening
in various hospitals and private institutions within our country.
The prejudices and current attitude of the Ministry of Health andthe Medical Associations go in this direction. We must urgently prepareawhitepaperthatincludesthebenefitsofcertaintherapiesincludedwithinthe integrative field so that we can begin tochange the official culture in our country and help one day tocreate Integrative MedicineDivisions.

CONTROVERSY AROUND THE USE OF OR
A LAND TROPICAL RADIO PROTECTORSIN MEDIAL TREATMENT USINGIONIZING RADIATION: FROM BASICRESEARCH TO CLINICALPRACTICE.
Alegría Montoro
Radiological Protection Service. University Hospital
La Fe (Valencia/SP)

Aparticularemphasiswillbediscussedrelatedtotheinvestigationanddevelopmentofnovelcompounds, known as medical countermeasures that are effective, non-toxic and minimize the damage caused by ionizing radiation. Research is needed due tothe increased use of ionizing radiation in different fields of applications. In medical applications there are two areas where the radiation doses patients receive may be high and where radiotherapy and interventional radiology would be justified. Secondly,at the occupational level, where workers are exposed to ionizing
radiation. In addition, the aerospace industry isinterestedininvestigatingcountermeasuresforastronautexposureinspacemissionsandfuturespace travel by the public. Lastly there is Defense
due to the nuclear terroristthreat.
Medical countermeasures are divided into three broad classes
depending on the length of time exposed to ionizing radiation.
Radio protectors are agents administered before radiation exposure to reduce the levelofradiationdamage.Radiationmitigatorsaredrugsadministeredshortlyafterirradiationbutbefore the manifestation of normal tissue toxicity. Radiation therapies are agentsadministered after the onset of obvious symptoms to reduce theseverity of the radiationresponse.
Radioprotectors, mitigators and radiation therapies will be discussed for medical applications, workers, both oral and topical,
that have been marketed, and approved by the FDA and also those under development in humans, as well as their mechanismsof action.

THE EFFICACY OF MICROIMMUNOTHERAPY AS A LOW DOSETHERAPY
Rigau, Josepa MD, PhD, experta en farmacogenética y farmacogenómica (Tarragona, Spain)
The concept of low doses or suboptimal doses in immunology appears for the first time in scientific literature during the60s, in order to define the concept of “desensitization”, me-

BOOK OF ABSTRACTS | 12th European Congress of Integrative Medicine · 1st International Symposium on Integrative Health and Education

aning inducing tolerance to an allergen. During the 90s, theterm “low dose allergen therapy (LDA)” already referred tothe association of an enzyme (glucuronidase) to an allergen in
low or ultra-low doses, a therapy aimed at creating tolerance
in lymphocytes B. Simultaneously, some references of Low doses Immunotherapy (LDI), targeting lymphocytes T in cancer
and autoimmune diseases, as well as new studies of low doses
medicines, showing less secondary effects while maintaining
their therapeutic effect, appeared in the bibliography.
Micro-immunotherapy, namely low and ultra-low doses
therapy, can hereby be defined as the use of immunomodulatory substances in low doses. Inthis regard, there is a large clinical experience mainly in the use ofcytokines, nucleic
acids and growth factors in low doses and administered insequential order, aiming at the maintenance or restorationof the physiological processes that may be altered in different pathologies with respect to the natural functioning of
the body. Indeed, most diseases are related to an alterationof the immune response. The following examples can be named: infections and viral reactivations, inflammatory, degenerative, chronic or autoimmune diseases and stress-related
conditions. Recent publications and clinical experience in thefield support its efficacy and application both in acute andchronic processes, either in prevention or intreatment.
Micro-immunotherapy may be then encompassed in an
integrative approach; namely, it encourages a global visionof health and the implementation of personalized treatment
plans in which the immune system takes a central role.

“MICROBIOTA AND IMMUN SISTEM”
Dra. Mª Dolores de la Puerta Soler. MD,Especialista en Medicina Integrativa y salud antienvejecimiento.
ABSTRACT:
We’ve all got a world of millions of microbes in our gut. The
question is, ¿what are they doing? ¿what do they encode andwhat are their metabolites?
Its action is very diverse but focusing on immunity, we can saythat the intestinal barrier is the first line of defense of the bodyagainst antigens and pathogens, it has an effective defensive activity, both physical and chemical.
The key to this protection are both the functional stability(qualitative and quantitative) of the microbiota and the many
molecules involved in the stability and homeostasis of the intestinal environment; the short-chain fatty acids, produced in abundance by the microbiota during the process of fiber degradation,
are the the most important metabolites.
The function of the immune system is much broader than ensuring an adequate response when the body is in contact witha potentially harmful foreign element, it is equally important its
ability to recognize and tolerate without response, non-harmfulor structural elements. The microbiota is essential to help theimmune system be effective in these processes of immune tolerance and identification.

41

A diet rich in fibre, probiotics, prebiotics and omega-3 contribute to the maintenance of the microbiota and its normal immune
function, improving immune tolerance and protecting individuals
from developmental allergies or other immune dysfunctions.

TOXIC CHEMICALS AND THEIREFFECTS ON HEALTH
William Shaw, Ph.D., Board certified in thefields of clinical chemistry and toxicology by
the American Board of Clinical Chemistry.
A high percentage of all people are now exposed to a soupof toxic chemicals. Toxic chemical exposure has been implicated as a major factor in impaired learning ability, attention
deficit, hyperactivity, pervasive developmental disorder, Alzheimer’s disease, depression, cancer, multiple sclerosis, andautism. Documentation of common chemicals in the environmentthat cause illnesses and their sources will be presented along withmethods to prevent exposure and to remove them when exposure
has already occurred. Metals are one of the most common groupsof toxic chemicals and the treatment of toxic metal exposure will be
examined.
Learning Objectives:
The attendee will learn how humans are exposed to a wide variety
of toxicchemicals.
The attendee will learn which toxic chemicals can cause humandisease.
Theattendeewilllearnthemosttoxicmetalsintheenvironmentaswellastraceelements that are toxic inexcess.
The attendee will learn techniques that can be used for the elimination of most toxic chemicals in the environment.

NURSING EDUCATION IN ICELAND
Gunnardosttir, TJ, Phd, Faculty of Nursing, Reykjavik (IS) Complementary Therapies:
The use of complementary therapies in Iceland among the public is rising. Within the health care system needs to be increased
discussion about how integrative health care can be strengthenandfurthereducationonthismatterisneededtoinformallhealthcarestudentsabout the use of complementary therapies and integrative
health for the benefit of patients. The FacultyofNursingattheUniversityofIcelandhasbeentakingpartinresearchingandeducating aboutcomplementarytherapiesandintegrativehealthpractices.Thishasbeendonebyoffering lectures and seminars at the National Hospital,
collecting data on the use within the National Hospital, among the
public and in nursing homes. The Faculty of Nursing has renewed its
curriculum and as part of that is now offering six credit course for all
nursing students about public health and self-mental care, complementary and integrative health. The course lectures andworkshop-

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BOOK OF ABSTRACTS | 12th European Congress of Integrative Medicine · 1st International Symposium on Integrative Health and Education

saboutcomplementarytherapiesand patient’ssymptomsandsafeuse.
Thismay alsobebeneficialforstudentstodealwithstressandincreaseself-carewhichmaybeofspecial importance now since recent studies
are showing that nursing students are reporting increased stress andburnout during theirstudies.

DIETARY THERAPY AND FOOD INCANCER. ADJUVANT TREATMENT.
Evidence and Strategy
Dr. Jorge Petez-Calvo Soler, expert in Nutritional
Medicine, Diet Therapy and food and integrative
treatment of the Oncological patient. Expert in
MTC. Acupuncturist. Environmental Medicine
Neuro focal medicine. Director of the Center for
Biological Medicine and Energy Nutrition. Barcelona
ABSTRACTThe conference presents the dietary strategy and food withproven positiveeffects againstcancer,applicabletoadietandfeedingforthepatientthroughoutitsentire process and cancer
treatment. It is based on the updated analysis of abundant current scientific evidence, which has been the foundation of the
dietary therapeutic prescriptions that have shown us such goodresults over more than 30 years of clinicalexperience:
The purpose of the diet and feed ingin cancer should be,not only to provide enough nutrients and energy for tissue replacement and basic body functions, but also to improve andstrengthen the patient’s immune functions. All this in orderto help them throughout their cancer process in their fightagainst cancer and the emergence of new metastases. To thisend, a strategy must be followed and the foods indicated in theabundant and most relevant current scientific evidence (mostly of vegetable origin), such as those recommended by WCRF
(World Cancer Research Foundation), AICR (American Institutefor Cancer Research), WHO (World Health Organization) andother reputable sources. It is also advisable to avoid or logicallylimit those foods that can be considered, according to current
evidence, risk factors or predisposing to cancer (for example
meat, poultry, processed, refined carbohydrates, sugars,...).
Food and nutrition can also be used to try to compensate
for the side effects of cancer treatments: surgery, pharmacotherapy, chemotherapy, radiotherapy or biological treatment.
A metabolic and food strategy, taking special care to protect
thedigestiveforceandconditioninthecancerpatient,withtheadequateinclusion of certain foods, such as whole grains, vegetable
proteins, fish, seeds, fresh vegetables and some fruits, in a foodstyle , with high digestibility and optimal nutritionalvalue,itisagreathelpforthepatienttohaveabetterphysicalcondition, energy
level and the best possible quality of life andwell-being.
We can thus help facilitate the best treatment success andimprove the quality of life,andallow,withbetterhealthalsointhepost-treatment,favortheprolongation of their life as long as
possible, and avoidrecurrences.

FERRITIN AND CANCER: HOW TO MAKE
VIRTUE OF THE PROBLEM
Dr. Santos Martín. Medical Doctor, PhD from the
University of Tübingen (Germany). Specialized
in oncology. Research professor at the UCAM of
Murcia.

Ironisacentralelementinalllivingorganismsbecausewithoutitcellproliferationand growth would not be possible. On the other hand, due
to its REDOX capacity, it contributesdirectlytotheformationoffreeradicalswiththeriskassociatedwiththem. In the tumor cell its role is essential in the proliferation, invasion, evasion of growth suppressors
and immunovigilance, immortalization, angiogenesis and metastasis.
Similarly, the elevation of ferritin levels is a factor of poor prognosis, as
it means increasing resistance to conventional treatments. Based on
this knowledge there is a whole series of procedures that use iron /ferritin as a selective anti-tumor therapeutic target.

USE OF ACUPUNCTURE IN A PAIN
UNIT. A REVIEW OF OVER 10 YEARS OF
PRACTICE
Javier Mata Estévez
Head of Section
Department of Anesthesiology and Pain Medicine, Son
Llàtzer University Hospital. Palma de Mallorca. Spain. (jmata@hsll.es)
Introduction
Acupuncture is widely used to manage chronic pain.
Growing evidence supports the effectiveness of acupuncture
to treat chronic low back, shoulder, neck, knee pain, and headaches (1). Additional data are emerging that support the useof acupuncture as an adjunct or alternative to opioids, thisidea is in line with reducing opioids in adults with chronic pain
conditions (2).
After stimulating an acupoint with a needle, the architecture of the connective tissue is altered.Mediatorsreleasedbythecellsstimulatenerveendingswithconsequentactivation
ofdifferentareasinthecentralnervoussystem(3-4).PETshowedthatacupunctureevokes a short- and long-term increase in
μ-opioid receptor availability in areas involved in pain processing, such as the caudate, thalamus, cingulate, insula, andamygdala, and this correlates with better clinical outcomes(5). The hypothalamic–pituitary–adrenal (HPA) axis also contributes to the efficacy of the acupuncture but its role is more
complex than simply deactivating this system(6).
Methods and materials
Electrocupuncture has been performed at the Pain Clinicof the Son Llàtzer University Hospital since 2006. It has sincegrown over 20% of the pain management interventions andBOOK OF ABSTRACTS | 12th European Congress of Integrative Medicine · 1st International Symposium on Integrative Health and Education

procedures. It is a medical procedure with a very wide range
of indications in the treatment of common chronic pain conditions. Acupuncture Clinical Pathway has been developed since2016, with the aim of improving the quality of care, reduce
variation and maximize the outcomes for this type of patient.
Acupunctureisofferedforthetreatmentofchronicmusculoskeletal,chroniclowback,neck, shoulder, headache and osteoarthritispain.
The application of inclusion/exclusion criteria for acupuncture treatment is essential. On the other hand, the type oftreatment and the number of sessions must be drawn up forassessing the effectiveness of the technique.
The risks of acupuncture are low although common side
effects (bleeding, soreness or bruising) may be observed. All
the information may be explained before the informed consent is signed.
Acupuncture treatment is chosen as the first choice or isoffered as an alternativewhen the usualanalgesicprocedurescannotbeappliedduetomedicationintolerance,allergyand/or
comorbidity. On the other hand, it is chosen as complementary treatment, when acupuncture is applied to increase theresponse to other pain-relievingprocedures.
Theelectroacupuncturetreatmentincludes1sessionperweekduring1month(4session). 30 minutes per session. Pain level(VAS for pain scale), medication use, anxiety and depressionstate(GoldbergAnxietyandDepressionScale),qualityoflife(SF-12)andquality of sleep (Pittsburg sleep quality index)
before the treatment ismeasured.
A new patient assessment will be undertaken at the end of
the treatment. The treatment will be continued until complete 10 sessions (every fifteen days) if there is a >30% reductionin the VAS for pain scale, medication use, or >30% improvement in the quality of life or quality of sleep scales.
When the 10 sessions are finished another assessment will
be performed and questions related to patient satisfaction
with the treatment received, and their expectations for improvement will also be included in the questionnaires.
Results
The analysis of the data was between 2015 and 2018. The
median age at the time of onset of treatment was 54±42(18,92), with 73,2% women. 35% of the Pain Clinic treatment was acupuncture.Electroacupuncturewasthetreatmentin26%ofthechronicmusculoskeletal
pain,29%inthelowbackpain,30%intheneckpain,14%intheshoulderpain,71%inthe
headache, and 40% in the osteoarthritis kneepain.
Betweenbaselineandweek16theVASforpainscaledecreased
byamean(SD)of1.3 (2.0) in low back pain; 3,7(2,9) in headacheand 3,8 (1,8) in OA kneepain.
In the preliminary results, there was a reduction in medicaluse, anxiety and depression an increase in quality of life andquality of sleep but there was no statistically significant difference.
Conclusion
Referral for a course of acupuncture treatment is a reasonable option for a patient with chronic pain (7). Acupuncture
Clinical Pathway may be used to improve the quality of care,
reduce variation and maximize the outcomes for this type of
patient.

43

References
Vickers AJ, Vertosick EA, Lewith G, MacPherson H, Foster NE,
Sherman KJ, Irnich D, Witt CM, Linde K; Acupuncture Trialists’ Collaboration. Acupuncture for Chronic Pain: Update of an Individual
Patient Data Meta-Analysis. J Pain. 2018 May;19(5):455-474. doi:
10.1016/j.jpain.2017.11.005. Epub 2017 Dec2.
EcclestonC,FisherE,ThomasKH,HearnL,DerryS,StannardC,KnaggsR,MooreRA. Interventionsforthereductionofprescribedopioiduseinchronicnon-cancerpain.
Cochrane Database Syst Rev. 2017 Nov 13;11:CD010323. doi:
10.1002/14651858.CD010323.pub3.
Minelli, E., Francescucci, B., Toschi, V., Iotti, S., Malucelli, E., &Maier, J. A. From East to West and Return: A Western Interpretationof Acupuncture. Altern Integr Med 2017, 6:1. DOI:10.4172/23275162.1000234
Ahn AC, Park M, Shaw JR, McManus CA, Kaptchuk TJ, et al. Electrical Impedance of Acupuncture Meridians: The Relevance of
Subcutaneous Collagenous Bands. 2010¸PLoS ONE 5(7): e11907.
doi:10.1371/journal.pone.0011907
Harris RE, Zubieta JK, Scott DJ, Napadow V, Gracely RH, et al.
(2009) Traditional Chinese acupuncture and placebo (sham) acupuncture are differentiated by their effects on mu-opioid receptors(MORs). Neuroimage 47:1077-1085.
Jones GT, Harkness EF, Nahit ES, McBeth J, Silman AJ, Macfarlane
GJ. Predicting the onset ofknee pain: results from a 2-year prospective study ofnew workers. Ann Rheum Dis2007;66:400–6
Vickers AJ, Cronin AM, Maschino AC, Lewith G, MacPherson H,
Foster NE, Sherman KJ, Witt CM, Linde K; Acupuncture Trialists’ Collaboration. Acupuncture for chronic pain: individual patient datameta-analysis. Arch Intern Med. 2012 Oct 22;172(19):1444-53.
doi:10.1001/archinternmed.2012.3654.

EFFECT OF EAR ACUPUNCTURE ON
PREGNANCY-RELATED PAIN IN THE
LOWER BACK AND POSTERIOR PELVICGIRDLE: A MULTICENTER RANDOMIZEDCLINICAL TRIAL
Vas J, Cintado MC, Aranda-Regules JM, et al. Effect of ear acupuncture on pregnancy-related painin the lower back and posterior pelvic girdle: A
multicenter randomized clinical trial. Acta Obstet
Gynecol Scand 2019;:aogs.13635. doi:10.1111/
aogs.13635
Introduction: Ear acupuncture carried out in primary care bytrained midwives, with no specialist training in acupuncture, may
be effective in alleviating pregnancy-related lower back and/or
posterior pelvic girdle pain (LBPGP). The objective of this study
was to assess the effect of ear acupuncture associated with standard obstetric care, in the primary-care setting, on LBPGP experienced by pregnant women.
Material and methods: This four-group, multicenter, randomized controlled trial was conducted at 18 public primary carecenters in three regions in Spain, with the participation of 220

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BOOK OF ABSTRACTS | 12th European Congress of Integrative Medicine · 1st International Symposium on Integrative Health and Education

pregnant women at 24-36 weeks of gestation, aged 18 years or
more, diagnosed with pregnancy- related LBPGP and who had
not previously received ear acupuncture.The trial was conductedfrom March 2014 to December 2016. Participants were randomly assigned (1:1:1:1) to receive standard obstetric care plus 2
sessions (over 2 weeks) of verum ear acupuncture, or nonspecific ear acupuncture, or placebo ear acupuncture, or standard
obstetric care alone. The primary outcome was change in pain
intensity, assessedusing avisualanaloguescale(0-100mm)frombaselinetotheendoftreatment (T2). Secondary outcomes included
change or presence of pain at 3 months (T3) and at 1 year (T4)
postpartum, and changes in responsesto the Roland-Morris disability questionnaire (RMDQ) and Short Form-12 Health Survey(SF-12) at the end oftreatment.
Results: A total of 55 women were randomized to each group, and205 completed the study. With respect to baseline values, the reduction in pain intensity among the verum ear acupuncture group vsstandard obstetric care was significantly greater, both at T2 (65.8%,
95%CI 56.2- 75.3 vs 25.1%, 95%CI 15.3-34.9) and at T3 (93.8%,
95%CI88.7-99.0
vs 67.9%, 95%CI 55.3-80.5). Moreover, significant changes were
found in the verum ear acupuncture group vs standard obstetric care
at T2, in reduced RMDQ scores (70.9%, 95%CI 61.8-80.1 vs 21.2%,
95%CI 8.633.7)andinincreasedSF-12scoresonthephysicalscale(40.5%,95%CI
31.5-49.4 vs 8.1%, 95%CI0.8-15.5).
Conclusions: After 2 weeks of treatment, ear acupuncture appliedby midwivesandassociatedwithstandardobstetriccaresignificantlyreduces lumbar and pelvic pain in pregnant women, improves quality oflife and reduces functionaldisability.

AURICULOPUNCTURE, EAR
ACUPUNCTURE, PREGNANCY-RELATEDLOW BACK PAIN, PREGNANCY-RELATEDPOSTERIOR PELVIC GIRDLE PAIN, PRIMARY
CARE, RANDOMIZED CONTROLLED TRIAL
Acupuncture techniques in chronic diseases – examples: Allergic Rhinitis
Prof. Dr. Benno Brinkhaus, Charité University Medicine Berlin, Germany
Allergic rhinitis (AR) affects an estimated about 15 percent of the
population in the industrialized countries.DirectyearlycostsforARinEuropeareestimatedat1.0–1.5billionEurosannually,whereas indirect
costs are estimated at 1.0–2.0 billionEuros.
A remarkable number of patients are turning for relief to Complementary and Alternative Medicine (CAM) including homeopathy, herbal medicine (of various traditional medicine systems), and acupuncture. The lifetime prevalence of CAM use in patients with AR ranges
from 27% to 46%, and most of the patients who have not yet used
CAM intend to do so in the future.
However,theevidencefortheefficacyofCAMforARisstilllimited.WeperformedthreeRCTtrialsto evaluate the efficacy as well as the effectiveness of acupuncture in allergic rhinitis providing good evidence foroverall and specific effects for acupuncture inAR.
The topic of this presentation will be to present data on the CAM
use in the field of AR and to provide the scientific evidence of acupuncture as well as to inform about the acupuncture and Chinese
medicine strategy used in our clinical trials as well as in our outpatient
clinic of complementary and integrative medicine at the Charité UniversitätsmedizinBerlin.

A NEW DIRECTION IN ACUPUNCTURE
RESEARCH FROM THE EAST
Dr Mike
Medical Director, British Medical Acupuncture Society
The vast majority of acupuncture research is performed in China and published in Chinese. It is inaccessible to most of us in theWest; however, it is increasingly being summarised in systematic
reviews in the English language. The quality of clinical research
published in English has been steadily improving, and in recent
years there have been not only improvements in the quality of
conduct and reporting of clinical trials but there has also been asubtle but dramatic change in the design of some research questions.
In my early days in the acupuncture field in the mid-nineties,
Chinese research in acupuncture seemed to be associated withimprobably good results, and it was one region of the world that
only published positive trials. Consequently, it was easy to dismiss.
That is no longer the case and in the last decade we have seen
the first large negative or neutral trials published in English language journals from China, and more recently still we have seensome very large trials of what to all intents and purposes are rather tight segmental electroacupuncture (EA) protocols ie what
appears to be a research question that tests a clear Western
neurophysiological mechanism rather than a more complex TCM
pattern-based concept.
In this presentation I will chart the change in clinical researchfrom China that started with ‘improbably good’ to become ‘huge
and entirely believable’, and what I perceive to be the adoptionof mechanism-based EA protocols.

(MORE THAN) 20 YEARS OF
INTEGRATION OF HOMEOPATHY IN THE
PUBLIC HEALTH SYSTEM OF THE REGION
OF TUSCANY AND THE EXPERIENCE OF
THE CLINIC HOMEOPATHIC HOSPITAL
OF LUCCA (ITALY)
Elio Rossi*, Marialessandra Panozzo*, Marco Picchi*, Cristina Noberasco*.
* Homeopathic Clinic of the Hospital Campo diBOOK OF ABSTRACTS | 12th European Congress of Integrative Medicine · 1st International Symposium on Integrative Health and Education

Marte, Lucca (Italy) – Regional center of reference
for homeopathy. Coordination center for Complementary Medicine of ASL Tuscany North West
Introduction
In response to the increasing demand of Complementary Medicine (CM) in the past few years by the Tuscan citizens, the region of Tuscany has started their integration in the healthcare
service. Since 1996, the Tuscan Regional Healthcare Plans (RHPs)
have been considering the role of Complementary Medicine(acupuncture, herbal medicine and homeopathy). Furthermore,
the Region of Tuscany decided to include CM in the Essential Levels of Assistance (ELA/LEA) in 2005. Accordingly, a network of
107 public clinics providing CM health services was built and therelative regulations (i.e., laws, bills, resolutions, etc.) were approved by the regional authorities.
The Homeopathic Clinic of Lucca was opened in 1998, followedby the Homeopathic Clinic for Women in 2003, and the Clinic for
CM and Diet in Oncology in 2013.
Aim
The aim of this article is to describe the pathway and results of
the integration process of CM in the public healthcare service inthe region of Tuscany (Italy) lasting more than 20 years.
Methods
Observational longitudinal studies conducted on 6,638 patients (4,343 in the general clinic, 1,774 in the women’s clinicand 436 in oncology) were consecutively examined from 2003 to
2018. The Outcome in Relation to Impact on Daily Living (ORIDL)
was generally used to assess outcomes.
Results
Comparing the clinical conditions before and after homeopathic treatment, improvement was observed in 88.8% of general
medicine patients with follow-up (45.1%); in particular, 68.1% of
the patients had a major improvement in or resolution (ORIDL+2,+3, +4) of their condition. In women, an improvement was
obtained in 74.1% cases and a major improvement in 61.2%. In
cancer patients with homeopathic and integrative treatment, asignificant improvement was observed for all the symptoms during anticancer therapy, particularly for hot flashes, nausea, depression, asthenia, andanxiety.
Conclusions
These results suggest that homeopathy can effectively be integrated with conventional medicine and that the Tuscan experience could provide a useful reference for developing national
and European regulations on the use of CM and homeopathy inpublic healthcare.

References
Rossi E., Picchi M., Panozzo MA, Di Stefano M., Baccetti S. Integration of Homeopathy and Complementary Medicine in Public Health System in Italy: Regional and National experiences. J Med Pers.
DOI10.1007/s12682-014-0187-0
Rossi Elio, Marco Picchi, Bartoli Paola, Panozzo Marialessandra, Di
Stefano Mariella, Puglia Monia, Da Frè Monica. Homeopathy in the
Public Health System: Outcome Data from the Homeopathic Clinic of
the Campo di Marte Hospital, Lucca (1998-2010). European Journal of
Integrative Medicine 6 (2014)39–47

45

RESEARCH LINES IN HOMEOPATHY:
WHERE DO WE COME FROM AND
WHERE ARE WE HEADING TO?
Authors:
Diaz‐Saez, Gualberto (1)Scientific Advisor, Asamblea Nacional de Homeopatía (ANH),Spain.
Abstract
The objective is to present a brief review of the advances madein research at different levels regarding homeopathy, and theperspective opened for the future research and knowledge.
The evidence that we already know allow us to be forcefulwhen it comes to stating that homeopathic medicines have specific biological effects, that it clinical application can produce clinical positive results which can additionally be relevant for publichealth.
New research designs and research lines will allow us discriminate between different homeopathic active principles (which
will allow better quality controls), define better the mechanismsof action, prove effectivity under real life conditions and for themost relevant health problems and also improve the methods
for the homeopathic consultation and the data of each medicine.
Key words:
research, homeopathy, review, methods
Full text:
In the laboratory research, if the physical‐chemical structuralchanges of the high dynamized dilutions are already well settled
through the MRI (1), now more precise methods allow to discover nanoparticles present in every dilution level (2) and polardyes (dynamic) that can identify the homeopathic active principles (3).
The ligand‐receptor type mechanisms of action described forGelsemium 5ch (4), Aspirine 15CH
and others, give way to electromagnetic interactions and changes in the geneticexpression
and the cellular proteome (studies by Dr. NiurkaMeneses).
Classicaldesignssuchasclinicaltrialofferfavourableresults(7,8)
butoftennon‐conclusiveones; however, new pragmatic designs
such as trials within cohorts ‐cmRCT (9) and TwiCs (10) are promising due to their capacity to better reflect the real practice. At
the same time, the studies tend to focus on cancer, woman heathand infections, which are some of the problems poorly answeredby the conventionalsystem.
Epidemiological studies such as EPI3 program in France (11)or British public hospitals (12,13) tend to become “integrative”
for example in the Tuscan Network of Integrative Medicine (14)or the ones made by the German assurance companies (15) because the real practice of complementary medicine is mixed andcomplex. They also focus more towards use and satisfaction of
the population (16).
Global systematic reviews have become stratified by illnesses,
by types of practice (individualised or not) and comparator (17),to allow more meaningful results. Meanwhile, “reviewsofreviews”arepublished(18,19)thatcarryandmultiplytheevaluation-

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BOOK OF ABSTRACTS | 12th European Congress of Integrative Medicine · 1st International Symposium on Integrative Health and Education

biasinsteadof
incorporating new data and improve its analysis, which bringsin the need of looking into those reports and re‐analysing themin order to face them (20,21).
All these studies allow us to understand better the mechanisms of action of homeopathy and show the scientific community
its interest, but for the homeopathy specialist there are othertype of studies that help improving the practise: case reports,that now tend to follow ad‐hoc quality guidelines (22), or large case series that are possible by means of platforms such as
CLIFICOL (23) and others. Another way of improving is to apply
a clinical thinking system more devoidofbiasandwiththecapacitytoprovidearesponseprobabilitytoagivenmedicine,which is
gaining interest thanks to the studies of Likelihood Ratio for thesymptoms of each homeopathic medicine (24) and the application of Bayesian probabilities to the clinical thinking (25).
Asacorollary,thelasttendenciesinviteustoimprovetheregistrationofthedataintheclinical records in a universal manner for
profiting it for research purposes. This will allow the applicationof the tools that have been explained; and well as others that in
the future, relying onthedevelopmentoftheanalysisofBigDatabyArtificialIntelligence,willallowimproveboth the homeopathic
practise and the achievement of positive researchresults.
References:
Demangeat JL. Nanosized solvent superstructures in ultramolecular aqueous dilutions: twenty years’ research using water proton
NMR relaxation. Homeopathy. 2013 Apr;102(2):87‐105. doi:10.1016/j.
homp.2013.01.001
Chikramane PS, Suresh AK, Bellare JR, Kane SG. Extreme homeopathic dilutions retain startingmaterials:Ananoparticulateperspective.
Homeopathy.2010Oct;99(4):231‐42.doi: 10.1016/j.homp.2010.05.006
Cartwright SJ. Solvatochromic dyes detect the presence of homeopathic potencies. Homeopathy. 2016 Feb;105(1):55‐65. doi:10.1016/j.
homp.2015.08.002
Bellavite P, Bonafini C, Marzotto M. Experimental neuropharmacology of Gelsemium sempervirens: Recent advances and debated issues. J Ayurveda Integr Med. 2018 Jan ‐ Mar;9(1):69‐74. doi:10.1016/j.
jaim.2017.01.010
Eizayaga F, Belon P, Desplat V, Aguejouf O, Doutremepuich C. Effectsof Ultra‐Low‐Dose Aspirin in Thrombosis and Haemorrhage. Homeopathy. 2019 Apr 20. doi: 10.1055/s‐0038‐ 1677495
Dei A, Bernardini S. Hormetic effects of extremely diluted solutions on
gene expression. Homeopathy. 2015 Apr;104(2):116‐22. doi:10.1016/j.
homp.2015.02.008
Frass M, Dielacher C, Linkesch M, Endler C, Muchitsch I, Schuster E,
Kaye A. Influence of potassium dichromate on tracheal secretions in critically ill patients. Chest. 2005 Mar;127(3):936‐41
Macías‐Cortés Edel C, Llanes‐González L, Aguilar‐Faisal L, Asbun‐Bojalil J. Individualized homeopathic treatment and fluoxetine for moderate
to severe depression in peri‐ and postmenopausal women (HOMDEP‐MENOP study): a randomized, double‐dummy, double‐ blind, placebo‐
controlled trial. PLoS One. 2015 Mar 13;10(3):e0118440. doi: 10.1371/
journal.pone.0118440
Viksveen P, Relton C, Nicholl J. Benefits and challenges of using
the cohort multiple randomisedcontrolledtrialdesignfortestinganinterventionfordepression.Trials.2017Jul
6;18(1):308.
doi:10.1186/
s13063‐017‐2059‐4
FibertP,PeasgoodT,ReltonC.RethinkingADHDinterventiontrials:feasibilitytestingoftwo treatments and a methodology. Eur J Pediatr. 2019
Jul;178(7):983‐993. doi: 10.1007/s00431‐019‐03374‐z

https://www.ncbi.nlm.nih.gov/pubmed/?term=epi3+duru
Spence DS, Thompson EA, Barron SJ. Homeopathic treatment forchronic disease: a 6‐year, university‐hospital outpatient observational
study. J Altern Complement Med. 2005 Oct;11(5):793‐8.
Sharples FM, van Haselen R, Fisher P. NHS patients’ perspective on complementary medicine: a survey. Complement Ther Med.
2003Dec;11(4):243‐8.
Rossi E, Di Stefano M, Picchi M, Panozzo MA, Noberasco C, Nurra L,
Baccetti S. Integration of Homeopathy and Complementary Medicine in
the Tuscan Public Health System and the Experience of the Homeopathic Clinic of the Lucca Hospital. Homeopathy. 2018 May;107(2):90‐98.
doi:10.1055/s‐0038‐1636839
WittCM,LüdtkeR,MenglerN,WillichSN.Howhealthyarechronicallyillpatientsaftereight
yearsofhomeopathictreatment?‐‐Resultsfromalongtermobservationalstudy.BMCPublic Health. 2008 Dec 17;8:413.
doi:10.1186/1471‐2458‐8‐413.
Rhee TG, Ng JY, Dusek JA. Utilization and perceived benefits of homeopathy and herbal therapiesinU.S.adults:Implicationsofpatient‐centeredcare.ComplementTherClinPract. 2017 Nov;29:9‐15. doi:10.1016/j.
ctcp.2017.07.003
https://www.hri‐research.org/hri‐research/learning‐more‐from‐existing‐ evidence/systematic‐review‐programme/
National Health and Medical Research Council. 2015. NHMRC Information Paper: Evidence on the effectiveness of homeopathy for treating health conditions. Canberra: National Health and Medical ResearchCouncil;2015
EASAC Working Group. Homeopathic products and practices: assessing the evidence and ensuring consistency in regulating medical claimsin the EU. EASAC;2017https://www.hri‐research.org/resources/homeopathy‐the‐debate/https://www.homeopatiasuma.com/desmontando‐fake‐news/
van Haselen RA. Homeopathic clinical case reports: Development of a supplement (HOM‐ CASE)totheCAREclinicalcasereportingguideline.ComplementTherMed.2016Apr;25:78‐ 85. doi:10.1016/j.
ctim.2015.12.019
https://www.clificol.net/project
Eizayaga JE, Pozzi MI, Canan MC, Saravia L. Prevalence and likelihood ratio of symptoms in patients with good therapeutic response
to Lycopodium clavatum. A retrospective study. Homeopathy. 2016
Feb;105(1):78‐83. doi:10.1016/j.homp.2015.09.002
Miglani A, Rutten L, Manchanda RK. Generalisability of prognostic
factor research: further analysis of data from the IIPCOS2 study. Homeopathy. 2017 Aug;106(3):155‐159. doi: 10.1016/j.homp.2017.06.001

HOMEOPATHY PRACTICE IN FRANCE.
EXPERIENCE AT THE HOSPITAL
Yecenia LOPEZ MARQUEZ, MD - General Practitioner- Homeopath, Lyon France
An increasing number of patients suffering chronic diseases,
such as cancer, are seeking other therapies that can help them
alleviate side effects of their treatments. In France, homeopathy
keeps developing as its use increases as a direct treatment to various pathologies and as a complementary treatment for chronic
diseases and cancer.
For cancer, homeopathy is only to be used as a complemen-

BOOK OF ABSTRACTS | 12th European Congress of Integrative Medicine · 1st International Symposium on Integrative Health and Education

tary treatment, not as an alternative. Therefore, it should be used
jointly with conventional treatments, and in full transparency andagreement with the medical team and the oncologist who are taking care of the patient. Homeopathy is the complementary medicine most used for patients with cancer.
The homeopathic treatment alleviates the side effects of chemotherapy and other therapies for cancer, which increases thepatient adherence to and ability to complete his/her conventional
treatment until the end. Homeopathy is a therapy without druginteractions, which improves tolerance to the conventional treatment and therefore brings more quality of life to the patient.
Homeopathy is widely used in France: 77% of French people
have used homeopathy at least once. 4000 specialized doctors
prescribe homeopathy, as well as many traditional General Practitioners and Midwives.
Homeopathy is also used in several French hospitals: more than
50 consultations are available, mainly in gynecology, oncology andradiotherapy Departments.
Dr. LOPEZ MARQUEZ is in charge of the homeopathy consultation within the hepatology and gastroenterology Department of
the leading “Hôpital de la Croix-Rousse” in Lyon, France. Based onclinical cases, she will present her experience of practical integrative medicine at the hospital.

PHYTOTHERAPY: RELEVANCE OFQUALITY ON SAFETY AND EFFICACY
Salvador Cañigueral, Roser Vila
Unitat de Farmacologia, Farmacognòsia i Terapèutica. Facultat de Farmàcia i Ciències de l’Alimentació.
Universitat de Barcelona. Av. Joan XXIII, 27-31. ES08028 Barcelona.
Phytotherapy is based on the use of herbal products for preventive or curative purposes. Phytotherapy needs products that guarantee the effect which is expected from them, and that have a known
level of risk. Herbal products from the same plant species are notalways equivalent and therefore do not necessarily have the same
properties1. Moreover, it is common for some plants, to find adulterated products on the market, as recently seen in the case of ginkgo
food supplements2.
Quality is a key factor of the herbal products because it guarantees the batch to batch reproducibility of safety and efficacy1,3. The
difficulties arising from the chemical complexity and variability ofherbal drugs and preparations thereof, as well as the complexity of
their production processes, can be overcome if quality is taken in account since the beginning of the production process, applying Good
Agriculture and Collection Practices (GACP) and Good Manufacturing Practices (GMP), together with an effort in the field of research
and an adequate quality control throughout the process. This control must ensure identity, purity (absence of contaminants, falsifications or adulterations), and content of active ingredients ormarkers.
The development of new herbal products should base the evidence of its efficacy and safety in double or triple blind, randomized,
controlled clinical trials without underestimating all the knowledge
provided by traditional use and the existing clinical experience. The
definition of product quality specifications is a prerequisite for initiating any clinical study1,3.
1 Cañigueral S, Vila R, Vanaclocha B. La Fitoterapia racional. In Vanaclo-47

cha B, Cañigueral S (Eds.).Fitoterapia.Vademécumdeprescripción.Capítulo1.Barcelona:Elsevier;2019:3-17.
2 Frommenwiler DA, Booker A, Vila R,Heinrich M, Reich E, Cañigueral
S. Comprehensive HPTLC fingerprinting as a tool for a simplified analysis
of purity of ginkgo products. J Ethnopharmacol 2019; 243,https://doi.org/10.1016/j.jep.2019.112084
3 Cañigueral S, Tschopp R, Ambrosetti L, Vignutelli A, Scaglione F, Petrini O. The development of herbal medicinal products: quality, safety andefficacy as key factors. Pharm Med 2008; 22:107-18.

FERTILITY IS NOT ONLY EMBRYOQUALITY
Carmen Salgado Sánchez. Licenciada en Farmacia, especializada en Bioquímica, Master en Nutrición Ortomolecular. Profesora Real Centro Universitario Reina
Cristina. Directora técnica de Herbarum Natura
Introduction
In Spain 6000 couples have problems to conceive, that is, 1 out of
every 4 born in the 70 will not have children. This becomes a healthproblem.
Each year 16,000 couples need help with fertility treatments to become parents.
June is the world month of Fertility Care. I love this concept because
it’s not about working with infertility, but about caring for fertility.
Let’s start at the beginning (What is infertility?) Impossibility of acouple getting a pregnancy by natural means after having normal sex
for more than 1 year.
Why is this happening:
Spaniards delay motherhood from 26 years in 1985 to 31 yearsnow.
Regarding male fertility according to the European Fertility Society
until 1986, the normal number of sperm in the ejaculate was 100 million / cc. From 1986 this normality is reduced to 60 million / cc andsince 1992 to 20 million /cc
There is no approach that works for everyone since each couple has
their ownsituation.
Focus only on ovulation
Many couples with fertility problems only have sex during the period of ovulation: Some couples try to “save” the sperm during theperiod of ovulation and then barely have sex during the month.
But the ideal is to have relationships every two or three days during
the month to maximize the possibilities.
Others believe that having more sex produces more possibilities
but this is not true. If it is for reproductivepurposes,havingsexseveraltimesadayoreveneverydaycancauseexhaustionand the couple canbegin to see sex as little more than a pre-ovulatorytask.
If you control the temperature or are using an ovulation prediction
kit, you may think that the idealis the day of ovulation. But it may belate because the ovum can be fertilized for 24 hours afterwards andthe sperm survives up to 24 or 48 hours so it is highly recommended that you have intercourse every other day on days 4 to 6 days
before ovulation and continue doing so for another 4 to 6 days
afterthis.

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BOOK OF ABSTRACTS | 12th European Congress of Integrative Medicine · 1st International Symposium on Integrative Health and Education

The importance of endocrine disruptors.
Not cleanse of endocrine disruptors is one of the mistakes thatcan be made in matters of infertility.
We remember that an endocrine disruptor is those substances
exogenous to the organism (natural or synthetic) that interfere withthe production, transport or action of natural hormones in our organism. Many times they behave like fake oestrogens or imitators
What are the main ones:
aromatichydrocarbons
Halogenatedhydrocarbons
Organochlorine compounds:Pesticides
Heavy metals (lead,cadmium)
All these products are contained in pesticides, insecticides, foodadditives and cosmetics and hygiene products, environmental pollution, platicos, UV filters of sun creams,
In male fertility affect the quality of sperm (remember that atleast half of cases of male sterility is of unknown cause) and could
be attributed to these endocrine disruptors.
Inwomentheseendocrinedisruptorsaffecttheglandssuchasovaries,pancreas(insulinresistance and fertility, polycystic ovarian
syndrome), adrenal (cortisol and iflamation) and thyroid (thyroid
disorders) and pituitary gland (high levels ofprolactin).
Contamination reaches newborns through the umbilical cord.
According to a US study on umbilical cord blood from fetuses,
these are soaked in a mixture of chemicals that include (mercury,gasoline derivatives, pesticides and the chemical PFOA used in Teflon). Up to a total of 287 chemical contaminants.
The damage of endocrine disruptors can be transgenerational, thatis, diagnosed to newborns or adults who were exposed when theirmother was developing them.
Hence the importance of making a history of environmental exposure in couples who have infertility problems.
A key point the hypophysis
The pituitary gland, which is located in the brain that controls our
sex hormones (estrogen, progesterone and prolactin) and is directly
affected by our stress, anxiety and attitude towards life. And these
therefore directly affect our fertility.
It has been proven how yoga helps to rebalance the hormonal axes
Meditation improves the rebalancing of neurological pathways that
influence hormonal control. Acupuncture produces endorphins that
help manage your stress, anxiety and daily emotions. These techniques that act from the mind help optimize the results of both natural
fertility but also assistedfertilitytreatmentsbecauseallthreehelptobalancethehormonalsystemwithouttheneed to take medicines orchemicals.
The importance of the immune system
The immune system is what defends us from the external aggressor
but also maintains an internal balance,allowsbloodvesselstoformatthetimeofimplantationandfirsttrimesterofpregnancyand these bloodvessels respond to the immunesystem.
At the same time there are white blood cells that come from theblood and that are located in the endometrium in the second phaseof the menstrual cycle and that they will decide: “well this is the moment of the formation of blood vessels” and they lower the guard of
the defense against the strangebecausetheembryois50%strange.Thisimmunebalancedependsoninternalandexternal factors and must be
worked on and taken intoaccount.
Untilnow,hehadfocusedmainlyonblooddisorders.Butrightnow,immunologyisalsoverystrong. For example, a woman with autoimmune

hypothyroidism problems can produce that this immune alteration
can alterfertility.
Immunological alterations in peripheral blood or endometrium canbe studied.
The problem that usually causes the alterations of the immune system is that either they never get pregnant (even with embryos of very
good quality) or they have recurrent miscarriages.
There are genetic or acquired immunological causes. The acquired
ones can be a hormonal or emotional imbalance.
Because many times the blood does not reach the uterus in a sufficient way and this can be due to:
Because blood is notfluid
because the blood vessels are scarce or too many or too much quality and this has to do with antibodies.
Even in this case even the state of the vaginal flora can affect thisimmunology.
state of the uterus
For many years fertility has focused on studying the embryo andthe quality of the ovum and sperm and everything pointed to a good
ovarian response and that there was a good morphologically embryoand they began to forget that it is not all that is needed. good implantation and then a placental development that keeps the pregnancy.
Andthishasmeantthatalthoughembryosofverygoodqualityareproduced,theydonotimplantor abortions occur and that is why we haveto see what else can bedone.
The uterus is the one that has to allow the passage of the sperm (ifwe speak of natural fertility) or allow the implantation of an embryo(if we talk about assisted fertility).
So in the uterus there are very important data some taken into account in a systematic way as the quality and thickness of the endometrium but others are not so well known. Because if the endometrium
is not well, pregnancy is not achieved.
These other parameters to consider are:Possible vascular or functional functional alterations (uterus in anteversion, retroversion, etc ...) that may be altering the vascularizationand therefore the fetal nutrition. The endometriumis importantinthefirst8-10weeksbecauseitisasourceofbloodandoxygenbecausethereisstillno placentaformed.
Acidificationsthatmaycomefrominflammations(suchasendometriosisorinfections)thatmaybe asymptomatic but prevent implantation of theembryoStress, poor diet, environmental pollution, cigarettes, caffeine, or
hormonal factors the endometriummaybeoutofsyncwiththegrowthoftheembryoanddonotbecomedyssynchronous and pregnancy
does not occur or recurrent lossesoccur.
All these data must be taken into account when preparing the lastphase that is the preparation of the land so that the embryo can be
implanted
Conclusions
Theapproachtofertilityproblemshastobeveryspecialized,takingintoaccountnotonlythequality of germ cells and the embryo and, moreover, it must be more and more individualized taking into accountthe status of immunological, hormones or field axes. For this there
are points that have to begin to be included in infertility approaches
suchas:Bad habits and lifestyle that can affect fertility in a profound way:
Stress alters hormonal axes and immunology.
Thebalancedversusunbalanceddietandthismayaffectthequalityofo-

BOOK OF ABSTRACTS | 12th European Congress of Integrative Medicine · 1st International Symposium on Integrative Health and Education

vulationandendometrium. For example: lack of vitamins E and D thatare immunomodulatory. Amount of fatty acids and types of fats thatmodulate the immune system and fluidify theblood.
Excess of caffeine (cola drinks) produce vasocontraction and alter
the circulation of the blood of theendometrium.
References
First Births to Older Women Continue toRise.
T.J. Mathews, M.S.; and Brady E. Hamilton, Ph.D. NCHS Data Brief ■ No. 152■ May 2014
Molecular characterization of the human microbiome from a reproductive
perspective Amir Mor, M.D., Ph.D.,a Paul H. Driggers, Ph.D.,b and James
H. Segars, M.D.b a Department of Obstetrics and Gynecology, Maimonides
Medical Center, Brooklyn, New York; and b Department of GynecologyandObstetrics,JohnsHopkinsSchoolofMedicine,Baltimore,Maryland.Fertility and Sterility® Vol. 104, No. 6, December 20150015-0282
Effect of vaginal probiotic lactobacilli on in vitro–induced sperm lipid peroxidation and its impact on sperm motility andviability.
ArcangeloBarbonetti,M.D.a,b,BenedettaCinque,Ph.D.c, MariaRosariaCaterinaVassallo, Ph.D.a,Salvatore Mineo, Ph.D.a Sandro Francavilla, M.D.a, Maria
Grazia Cifone, Ph.D.c, Felice Francavilla, M.D.a. Fertility and Sterility Vol. 95, No.
8, June 30,2011a Division of Maternal-Fetal Medicine and b Department of Obstetrics and Gynecology, University of South Carolina– Greenville School of Medicine, Greenville Health Systems, Greenville, South Carolina. Fertility and Sterility® Vol. 104,
No. 6, December 20150015-0282
5. A strategy to validate a selection of human effect biomarkers using adverse
outcome pathways: Proof of concept for phthalates and reproductive effects.
Kirsten A. Bakena, Nathalie Lambrechtsa, Sylvie Remya, Vicente Mustielesc,Andrea Rodríguez-Carrillod, Christiana M. Neophytouf, Nicolas Oleac, Greet
Schoetersa. Environmental Research 175 (2019)235–256

THE IMPORTANCE OF ANAMNESIS IN
LYME DISEASE AND CO- INFECTIONS:FUNDAMENTAL ASPECTS AND
CHALLENGES WE FACE.
Dr. Carmen Navarro Muros. Medical Doctor. Director of the GAIA Clinic. Expert in micronutritionand diet therapy. Environmental Medicine. (Madrid/SP)
LymediseaseisthemostcommonzoonoticdiseaseinEuropewithanestimated number of cases per year between 650,000 and 850,000,
defined as the infectious disease caused by the bite of a tick, whichtransmits a bacterium Borrelia Burgdorefri, being its serological diagnosis. And being able to give rise, in a great number of cases, to achronic disease that generates a diverse symptomatology and multisystemic damage.
Although the reality is very different, in my presentation I am goingto show the difficulty in the diagnosis of this disease, because:
There are data that indicate that the so-called Lyme disease can begenerated by vectors different from the tick, including the transpla-

49

centalway.
It may involve other species of Borrelia, not only Burgdorferi, andmay accompany Borrelia in the disease, another series of bacteria,
even parasites, which also generate characteristicsymptoms,
The clinic of the disease is multisystemic and is not located in an
organ or system.
Scientifically validated serological diagnoses generate a high rate offalse negatives.
For all these reasons, in the face of this variability in aetiology, clinical and diagnosis,
an exhaustive anamnesis is one of the most important resources
we must take into account if we want to make a correct and early
diagnosis of the disease.
If we unify criteria in a common questionnaire that includes thecircumstances of the beginning of the disease, the symptomatology,
diagnostic tests performed if therehavebeen,evolution,treatmentortreatmentsiftheyhavebeenprescribed at any time and the residual
symptomatology after treatment, this may currently constitute thebest tool for the diagnosis of Lyme disease and co-infections as well as
providing us with a real definition of its incidence and the difficulties
to face both diagnosis andtreatment.

References
Oksi J, Uksila J, Marjamaki M, Nikoskelainen J, Viljanen MK. Antibodies
against wholesonicatedBorreliaburgdorferispirochetes,41-kilodaltonflagellin,andP39protein in patients with PCRor culture-proven late Lyme borreliosis. J Clin Microbiol. 1995 Sep;33(9):2260-4
Karma A, Seppala I, Mikkila H, Kaakkola S, Viljanen M, Tarkkanen A. Diagnosis and clinical characteristics of ocular Lyme borreliosis. Am J Ophthalmol. 1995 Feb;119(2):127-35.
Chmielewski T, Fiett J, Gniadkowski M, Tylewska-Wierzbanowska S. Improvement in the laboratory recognition of lyme borreliosis with the combination of culture and PCR methods. Mol Diagn.2003;7(3-4):155-62.
Brown SL, Hansen SL, Langone JJ. (FDA Medical Bulletin) Role of serology
in the diagnosis of Lyme disease. JAMA. 1999 Jul7;282(1):62-6.
Bertrand E, Szpak GM, Piłkowska E, Habib N, Lipczyńska-Lojkowska W,
RudnickaA,Tylewska-WierzbanowskaS,KulczyckiJ..Centralnervoussysteminfection caused by Borrelia burgdorferi. Clinico-pathological correlation of
three post-mortem cases. Folia Neuropathol.1999;37(1):43-51.
Breier F, Khanakah G, Stanek G, Kunz G, Aberer E, Schmidt B, Tappeiner
G. Isolation and polymerase chain reaction typing of Borrelia afzelii froma skin lesion in a seronegative patient with generalized ulcerating bullous
lichen sclerosus et atrophicus. Br J Dermatol. 2001Feb;144(2):387-92.
Brunner M, Sigal LH. Immune complexes from serum of patients withlyme disease contain Borrelia burgdorferi antigen and antigen-specific antibodies: potential use for improved testing. J Infect Dis. 2000
Aug;182(2):534-9. Epub 2000 Jul28.
Brunner M. New method for detection of Borrelia burgdorferi antigen
complexed to antibody in seronegative Lyme disease. J Immunol Methods.
2001 Mar 1;249(1- 2):185-90.
Wang P, Hilton E. Contribution of HLA alleles in the regulation of antibody production in Lyme disease. Front Biosci. 2001 Sep1;6:B10-6.
Dinerman H, Steere AC. Lyme disease associated with fibromyalgia. Ann
Intern Med. 1992 Aug15;117(4):281-5.
Fraser DD, Kong LI, Miller FW. Molecular detection of persistent
Borrelia
burgdorferiinamanwithdermatomyositis.ClinExpRheumatol1992Jul-Aug;10(4):387-

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90.DejmkovaH,HulinskaD,TegzovaD,PavelkaK,GatterovaJ,VavrikP.Seronegative Lyme arthritis caused by Borrelia garinii. Clin Rheumatol.
2002Aug;21(4):330-4.
Oksi J, Mertsola J, Reunanen M, Marjamaki M, Viljanen MK. SubacutemultiplesiteosteomyelitiscausedbyBorreliaburgdorferi.ClinInfectDis1994Nov;19(5):891-6.
Honegr K, Hulinska D, Dostal V, Gebousky P, Hankova E, Horacek J, Vyslouzil L, Havlasova J. Persistence of Borrelia burgdorferi sensu lato in patientswith Lyme borreliosis. Epidemiol Mikrobiol Imunol. 2001Feb;50(1):10-6.
Wilke M, Eiffert H, Christen HJ, Hanefeld F. Primarily chronic and cerebrovascular course of Lyme neuroborreliosis: case reports and literature
review. Arch Dis Child 2000Jul;83(1):67-71.
Schubert HD, Greenebaum E, Neu HC. Cytologically proven seronegative
Lyme choroiditis and vitritis. Retina.1994;14(1):39-42.
Haupl T, Hahn G, Rittig M, Krause A, Schoerner C, Schonherr U, Kalden
JR, Burmester GR. Persistence of Borrelia burgdorferi in ligamentous tissue
from a patient with chronic Lyme borreliosis. Arthritis Rheum 1993 Nov;
36(11):1621-6.
Hulinska D, Krausova M, Janovska D, Rohacova H, Hancil J, Mailer H. Electron microscopy and the polymerase chain reaction of spirochetes fromthe blood ofpatients with Lyme disease. Cent Eur J Public Health 1993 Dec;
1(2):81-5.
Liegner KB, Shapiro JR, Ramsay D, Halperin AJ, Hogrefe W, Kong L. Recurrent erythema migrans despite extended antibiotic treatment with minocycline in a patient with persisting Borrelia burgdorferi infection. J. Am.
Acad. Dermatol. 1993 Feb;28(2 Pt 2):312-4.
Preac Mursic V, Marget W, Busch U, Pleterski Rigler D, Hagl S. Kill kinetics
of BorreliaburgdorferiandbacterialfindingsinrelationtothetreatmentofLymeborreliosis. Infection. 1996Jan-Feb;24(1):9-16.
Mursic VP, Wanner G, Reinhardt S, Wilske B, Busch U, Marget W. Formation and cultivation of Borrelia burgdorferi spheroplast-L-form variants.
Infection 1996 Jul- Aug;24(4):335.
Millner M. Neurologic manifestations of Lyme borreliosis in children
Wien Med Wochenschr. 1995;145(7-8):178-822000;101(1):5-7.
Pikelj F, Strle F, Mozina M. Seronegative Lyme disease and transitory
atrioventricular block. Ann Intern Med 1989 Jul1;111(1):90.
Pachner AR. Borrelia burgdorferi in the nervous system: the new “great
imitator”.Ann N Y Acad Sci.1988;539:56-64.
Dattwyler RJ, Volkman DJ, Luft BJ, Halperin JJ, Thomas J, Golightly MG.
Seronegative Lyme disease. Dissociation of specific T- and B-lymphocyte
responses to Borrelia burgdorferi. N Engl J Med. 1988 Dec1;319(22):1441-6.
Donta ST. Tetracycline therapy for chronic Lyme disease. Clin Infect Dis
1997 Jul;25 Suppl1:S52-6.
PleyerU,PriemS,BergmannL,BurmesterG,HartmannC,KrauseA.Detection of Borrelia burgdorferi DNA in urine of patients with ocular Lyme borreliosis. Br J Ophthalmol. 2001May;85(5):552-5.
EldoenG,VikIS,VikE,MidgardR.[LymeneuroborreliosisinMoreandRomsdal] Tidsskr Nor Laegeforen. 2001 Jun30;121(17):2008-11.
KaiserR.False-negativeserologyinpatientswithneuroborreliosisandthevalue of employing of different borrelial strains in serological assays. J Med
Microbiol. 2000 Oct;49(10):911-5.
Mikkila H, Karma A, Viljanen M, Seppala I. The laboratory diagnosis of ocular Lyme borreliosis. Graefes Arch Clin Exp Ophthalmol.
1999Mar;237(3):225-30.

OksiJ,ViljanenMK,KalimoH,PeltonenR,MarttiaR,SalomaaP,Nikoskelainen
J, Budka H, Halonen P. Fatal encephalitis caused by concomitant infection
with tick- borne encephalitis virus and Borrelia burgdorferi. Clin Infect Dis.
1993Mar;16(3):392-6.
Skripnikova IA, Anan’eva LP, Barskova VG, Ushakova MA. [The humoral immunological response of patients with Lyme disease.]Ter
Arkh1995;67(11):53-6.
Klempner MS, Schmid CH, Hu L, Steere AC, Johnson G, McCloud B, Noring R, Weinstein A. Intralaboratory reliability of serologic and urine testingfor Lyme disease. Am J Med. 2001 Feb15;110(3):217-9.
Banyas GT. Difficulties with Lyme serology. J Am Optom Assoc. 1992
Feb;63(2):135-9.
FallerJ,ThompsonF,HamiltonW.FootandankledisordersresultingfromLyme disease. Foot Ankle. 1991Feb;11(4):236-8.
Nields JA, Kueton JF. Tullio phenomenon and seronegative Lyme borreliosis. Lancet. 1991 Jul13;338(8759):128-9.
Schutzer SE, Coyle PK, Belman AL, Golightly MG, Drulle J. Sequestrationof antibody to Borrelia burgdorferi in immune complexes in seronegative
Lyme disease. Lancet. 1990 Feb10;335(8685):312-5.
Paul A. [Arthritis, headache, facial paralysis. Despite negative laboratory tests Borrelia can still be the cause]. MMW Fortschr. Med 2001
Feb8;143(6):17.
Ang CW, Notermans DW, Hommes M, Simoons-Smit AM, Herremans T.
Large differences between test strategies for the detection of anti-Borrelia
antibodies are revealed by comparing eight ELISAs and five immunoblots.
Eur J Clin Microbiol Infect Dis. Published oline: 27 Jan2011
Wojciechowska-Koszko et al.: Serodiagnosis of borreliosis: indirect immunofluorescence assay, enzyme-linked immunosorbent assay and immunoblotting. Arch Immunol Ther Exp (Warsz.) 2011 Feb;59(1):69-77. Epub
2011 Jan22.
Durovska J. et al.: Our experience with examination of antibodies against
antigensofBorreliaburgdorferiinpatientswithsuspectedlymedisease.BratislLekListy. 2010;111(3):153-5.
Coyle PK, Schutzer SE, Deng Z, Krupp LB, Belman AL, Benach JL, Luft BJ. DetectionofBorreliaburgdorferi-specificantigeninantibody-negativecerebrospinalfluid in neurologic Lyme disease. Neurology. 1995Nov;45(11):2010-5.
SteereAC,BerardiVP,WeeksKE,LogigianEL,AckermannR.Evaluationofthe
intrathecal antibody response to Borrelia burgdorferi as a diagnostic testfor Lyme neuroborreliosis. J Infect Dis 1990Jun;161(6):1203-9.
Logigian EL, Kaplan RF, Steere AC. Successful treatment of Lyme encephalopathy with intravenous ceftriaxone. J Infect Dis1999;180:377–83.
Logigian EL, Kaplan RF, Steere AC. Chronic neurologic manifestations of
Lyme disease. N Engl J Med1990;323:1438–44.
Pfister HW, Preac-Mursic V, Wilske B, Einhaupl KM, Weinberger K. LatentLyme neuroborreliosis: presence of Borrelia burgdorferi in the cerebrospinal fluid without concurrent inflammatory signs. Neurology.
1989Aug;39(8):1118-20.
Preac-MursicV,WeberK,PfisterHW,WilskeB,GrossB,BaumannA,ProkopJ.
Survival of Borrelia burgdorferi in antibiotically treated patients with Lymeborreliosis. Infection. 1989Nov-Dec;17(6):355-9.
Peter O, Bretz AG, Zenhausern R, Roten H, Roulet E. Isolation of Borrelia
burgdorferiinthecerebrospinalfluidof3childrenwithneurologicalinvolvement.Schweiz Med Wochenschr 1993 Jan 13; 123(1-2):14-9.
Oksi J, Kalimo H, Marttila RJ, Marjamaki M, Sonninen P, Nikoskelainen J,

AbererE,KerstenA,KladeH,PoitschekC,JureckaW.HeterogeneityofBorrelia burgdorferi in the skin. Am J Dermatopathol. 1996 Dec;18(6):571-9.
Steere AC. Seronegative Lyme disease. JAMA. 1993 Sep15;270(11):1369.
Preac-MursicV,PfisterHW,SpiegelH,BurkR,WilskeB,ReinhardtS,Bohmer
First isolation of Borrelia burgdorferi from an iris biopsy. J. Clin. Neuroophthalmol. 1993Sep;13(3):155-61.

Viljanen MK. Inflammatory brain changes in Lyme borreliosis. A report on
three patients and review of literature. Brain 1996 Dec; 119 ( Pt 6):2143-54.
Kaiser R, Rasiah C, Gassmann G, Vogt A, Lucking CH. Intrathecal antibody
synthesis in Lyme neuroborreliosis: use of recombinant p41 and a 14-kDa
flagellin fragment in ELISA. J Med Microbiol. 1993Oct;39(4):290-7.Honegr
K, Hulinska D, Dostal V, Gebousky P, Hankova E, Horacek J, Vyslouzil L,

BOOK OF ABSTRACTS | 12th European Congress of Integrative Medicine · 1st International Symposium on Integrative Health and Education

Havlasova J. Persistence of Borrelia burgdorferi sensu lato in patients with
Lyme borreliosis. Epidemiol Mikrobiol Imunol 2001Feb;50(1):10-6.
Lawrence et al.: Seronegative chronic relapsing neuroborreliosis. Eur.
Neurol. 1995;35(2):113-7.
ILADS, Evidence-based guidelines for the management of Lyme disease.2004.http://ilads.org/files/ILADS_Guidelines.pdf(AnexoVIII)
Cameron,d.;gaito,a.;harris,n.;bach,g.;bellovin,s.;bock,k.;bock,s.;burrascano, j.; dickey, c.; horowitz, r.; phillips, s.; meer-scherrer, l.; raxlen, b.; sherr,v.; smith, h.; smith, p.; stricker, r.: Evidence-based guidelines for the management of Lyme disease. Expert Rev Anti Infect Ther 2 (2004), S1–13.56.
Deutsche Borreliose-Gesellschaft e. V. Diagnosis and treatment of Lyme borreliosis – Guidelines. Décembre 2010.http://www.borreliose-gesellschaft.
de/Texte/guidelines.pdf
57- 1985: Schlesinger PA, Duray PH, Burke BA, Steere AC and Stillman
MT.Maternal- FetaltransmissionoftheLymediseasespirochete,BorreliaBurgdorferi.AnnInternMed. 1985;103(1):67-8.
58-1985: In MMWR. ‘Lyme disease and cases occurring during pregnancy’ Vol 34, No 25, June 28, 1985), pp. 376378. Published by Centers for Disease Control and Prevention (CDC).
1987: MacDonald A, Benach J, Burgdorfer W. Stillbirth following Maternal Lyme Disease. New York State Journal of Medicine vol 87, November1987.
1994:ElsukovaL,KorenbergE,KozinG.ThePathologyofPregnancyandtheFetus in Lyme disease. Meditsinskaia parazitologiia i parazitarnye bolezni,
Oct,1994.
*translated from Russian
61-2003: Horst, H. Borrelieninfektion in der Schwangerscharft und durch
Bluttransfusionen. In H. Horst (ed.) Zeckenborreliose Lyme-Krankheit bei
Mensch und Tier (4th ed., pp. 132-137). Balingn, Germany: Spitta Vergag
GmbH & Co., KG.
**translated from German
2008: Hercogova J, Vanousova D. Syphilis and borreliosis during pregnancy. Dermatologic Therapy, Vol. 21, 2008,205-209.
63-2017: O’Brien J, Hamidi O. ‘Borreliosis Infection during Pregnancy’.
Ann Clin Cytol Pathol 3(8). Oct. 2017.
64-2018: Luche-Thayer J, Perronne C, Meseko C. Obstruction to Treatments Meeting International Standards for Lyme and Relapsing Fever Borreliosis Patients. World Academy of Science, Engineering and Technology
International Journal of Law and Political Sciences. Vol 12, No: 6, 2018

THE DISRUPTED IMMUNE RESPONSE
INLYMEPol De Saedeleer Pharm. D. Chairman of the European ILADS Committee . Board Director of ILADEF. (BG)
Goal of this lecture
How does our immune system work when weare underattack?
What is the issue in chronic viralinfections?
What is the issue inLyme?
What more causative issues can disrupt our immunesystem andmake us more susceptible for development of a chronic (multi-) infectiouspahtology?
2 Healthy immune system meant to protect us & defend against
threats, pathogens andvectors
Complicated mistakes

51

3 Our immune response consists ofAn immediate non-specificpart
Innate immune response
An organized part with amemory
Adaptive immune response
5In areas where microbes might enter: digestive tract, lungs,…MHC
binds to antigens derived from pathogens and will determine if there
is compatibility
IinteractswithCD8receptorsonthesurfaceof Cytotoxic T cells
for furtherdestruction
MHC II interacts with CD4 receptors on naïve T helper Cells for further organization of the adaptiveimmunity
MHC II interacts with CD4 receptors on naïve T helper Cells for further organization of the adaptiveimmunity
Interaction with APC through MHC Surface proteins
CD4 naiive Tcells can only recognize antigens presented on MHC
class IIcarriers
CD8 cytotoxic cells can only recognize antigens presented on MHC
class Icarriers
Immune cells communicate by releasingcytokines In Th1 cytokines
activate
Cytotoxic T Cells, Macrophages, Natural KillerCells
Th1 immunity is our immunity if pathogens hide inside cells
Cytotoxic T Cells are built to detect antigens on the surface of infected cells + they destroy the infected cells
Natural Killer Cells don’t need to recognize antigens on the surface
of infected cells , they can eliminate foreign cellsjust as uce immunoglobulins to mark themicrobes
PaoliniR,BernardiniG,MolfettaR.NKCellsandinterferons:CytokinegrowthFactorRev.2015Apr;26(2):113-20.doi:10.1016/j.Cytogfr.20014.11.003.Epub2014 Nov13
What is the issue in Chronic Viral Infections?
Virus = Obligate intracellular parasite
cannot reproduce outside host cells, meaning that the parasite’s
reproduction is entirely reliant on intracellularresources.
Obligate intracellular parasites of humans include:
VirusesCertain bacteria,including:
Chlamydia, and closely relatedspecies
Rickettsia
Coxiella
Certain species ofMycobacterium
OXIDATIVE STRESS DURING VIRAL INFECTION
Different mechanisms:
ViralactivationofphagocyticcellstoreleaseROSandpro-oxidant cytokines
Virally induced inhibition of antioxidant enzymes such as SOD
affects pro-/antioxidant balance
Virus-induced oxidative stress is affecting Natural Killer Cellactivity
Virus-induced oxidative stress is causing damage to the host ( mitochondrial damage)Peterhans , Sendai : virus stimulates chemiluminescence in mousespleen cells.Biochem.Biophys.Res.Commun.91:383-392;1979
Cancer Biother Radiopharm. 1998 Aug;13(4):275-90. Susceptibilityof natural killer (NK) cells to reactive oxygen species (ROS) and their

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BOOK OF ABSTRACTS | 12th European Congress of Integrative Medicine · 1st International Symposium on Integrative Health and Education

restoration by the mimics of superoxide dismutase (SOD). Nakamura K1,Matsunaga
19
Antioxidants make the difference :Beck MA , Handy J , Levander OA
The role of oxidative stress in viral infections
mice carrying Coxsackie virus CVB3 having a diet deficient in antioxidants, the infection is much moresevere
myocarditis vs benign=
immune functions and defense systems were altered inmice having more oxidativestress
Schwarz KB
Oxidative stress during viral infection/review
Several reports show decreased levels of glutathione in lymphocytes and other tissues in HIV-infected individuals
20
What strategy should we apply to eradicate chronic viralinfections
more efficiently ?
What additional supportive remedies do we need to limit host defense?
Empower our intracellularimmunity= T cell immunity & Natural Killer Cells
The approach of utilizing antioxidants both to decrease virus-induced tissue damage and decrease viral replication may prove antioxidants to be very useful in treating viral infections
remediestoprotect,rebuildandoptimizemitochondrial metabolism
21
Empower our intracellularimmunity= T cell immunity & Natural Killer Cells
Low doseNaltrexone
Brief blockade of opiod receptors to upregulate endorphins and rebalance immunity + improve NK cells
Transfer factors are like a cross between interleukins and antibodies
Carrying messages from immune cell to immune cell like interleukins= General strengthening of Th1
Toljan, Karlo, and Bruce Vrooman. “Low-dose naltrexone (LDN)—
review oftherapeu- tic utilization.” Medical Sciences 6.4 (2018):82.
Wang J. et al. Green tea epigallocatechin-3-gallate modulates differentiation of naïve CD4⁺ T cells into specific lineage effector cells. 2013
Apr;91(4):485-95.
Bruck J. et al. Nutritional control of IL-23/Th17-mediated autoimmune disease through HO-1/STAT3 activation.Sci Rep. 2017;7:44482.
Silva AM. Et al. Resveratrol as a Natural Anti-Tumor Necrosis Factor-α Molecule: Implications to Dendritic Cells and Their Crosstalkwith Mesenchymal Stromal Cells. PLoS One. 2014; 9(3): e91406.
= rebuilding balance Th1/Th2/Th17
Bindingtoantigensoninfectedcellslikeantibodies
More immune modulators: Curcumin, GreenTea, Resveratrol
22
The approach of utilizing antioxidants may prove to be veryuseful
To decrease virus-induced damage to mitochondria andtissues
To improve NK cell activity by reducing oxidative attack on NKCells
LiposomalGlutathione
Sinha, Raghu, et al.
Oral supplementation with liposomal glutathione elevates bodystores of glutathione and markers of immune function. European
journal of clinical nutrition 72.1 (2018): 105.
Green Tea,Resveratrol

Shi XL, Ye JP, Leonard SS, Ding M, Vallyathan V, Castranova V, Rojanasakul Y, Dong ZG. Antioxidant properties of (–)-epicatechin-3-gallate
and its inhibition of Cr(VI)-induced DNA damage and Cr(IV)- or TPA-stimulated NF-kappa B activation. Mol Cell Biochem. 2000;206:125–132.
Ojo OO, Kabutu FR, Bello M, Babayo U. Inhibition of paracetamol-induced oxidative stress in rats by extracts of lemongrass (Cymbropogon citratus) and green tea (Ca- mellia sinensis) in rats. Afr J
Biotechnol. 2006:5, 1227–1232.
Hakim IA, Harris RB, Brown S, Chow HHS, Wiseman S, Agarwal S,
Talbot W. Effect of increased tea consumption on oxidative DNA
damage among smokers: A ran- domized controlled study. J Nutr.2003;133:3303S–3309S
Lee SF, Liang YC, Lin JK. Inhibition of 1,2,4-benzenetriol-generated
active oxygen species and induction of phase II enzymes by green tea
polyphenols. Chem.-Biol Inter- act. 1995;98:283–301.
Chandronitha C, Ananthi S, Ramakrishnan G, Lakshmisundaram R,
Gayathri V, Vasanthi HR. Protective role of tannin-rich fraction of Camellia sinensis in tissue arse- nic burden in Sprague Dawley rats. Hum
Exp Toxicol. 2010;29:705–719.
Liang, Huiyun, and Walter F. Ward. “PGC-1α: a key regulator of energy metabolism.” Advances in physiology education 30.4(2006):145151. 23
Remedies to protect, rebuild and optimize mitochondrial Metabolism
Phospholipids (lipid Replacement therapy)
Nicolson, Garth L., Robert Settineri, and Rita Ellithorpe.
Lipid replacement therapy with a glycophospholipid formulation
with NADH and CoQ10 significantly reduces fatigue in intractablechronic fatiguing illnesses and chronic Lyme disease patients.
International Journal of Clinical Medicine 3.03 (2012):163.
24
Next to the mechanical damage caused by the generation of free
radicals, viruses further impair the different processes inside themitochondria
Calciumhomeostasis
Calcium is the most abundant element in the cell, acting as a second messenger to regulate many cellularprocesses
MMP, mitochondrial Membrane Potential, regulates Calciumuptake
More Calcium stimulates the oxidative phosphorylation and the entire mitochondrial machinery, what results inhigher
ATP output.
A number of viruses alter the Calcium regulatory activity of the cellfor their survival = HSV 1 causes a decline of 65%in
Calcium uptake
25
Electron TransportChain
The mitochondrial respiratory chain is the main and most significant source of ROS- in thecell.
Superoxide (O ) is the primary ROS produced bymitochondria
In normal state² there is little or no leakage but in stressconditions
Leakage takes place mainly at complexIII
ROS are generated during viral infection to limit viral replication
but sometimes viruses cause increased oxidative stress inhostcells to createchaos.
26
DNA synthesis andstockage

BOOK OF ABSTRACTS | 12th European Congress of Integrative Medicine · 1st International Symposium on Integrative Health and Education

HSV depletes mitochondrialDNA
Inhibition of fatty acidoxidation
Reduced oxidative phosphorylation and ATPgeneration27
Mitochondrial Quality controlprocess
Mitochondria constitute a population of organelles that continuously elongate (fusion), divide (fission) and undergo a controlled
turnover (mitophagy)
Viruses impair mitochondrial dynamics and qualitycontrol
Viruses as modulators of mitochondrial functions. Sanjeev K Anandand Suresh K Tikoo, Advances in virology / Volume 2013, article ID
738794
Mitochondrial dynamics and viral infections : A close nexus, Moshin
Khan , Ghulam Hussain Syed , Seong-Jun Kim, Division of Infectious diseases , De- partment of Medicine , university of California , San Diego, La Jolla, CA, USA
28
Remedies to protect, rebuild and optimize mitochondrial Metabolism(continued)
Nutritional Molecules to optimize mitochondrial conversionof carbohydrates & fatty acids intoATP:
Acetyl Carnitine, Q10, R-ALA, Ribose & Creatine, Vit B Cofactors,
Magnesium Malate
29
What is the issue in Lyme?
Lyme is a chronic immune suppression andinflammatory response- where the immune response wasunadapted
Borrelia doesn’t act like a bacteria but like an intracellular parasite:
Borrelia’sgoalisnottodestroy/digestthehostbutto benefit from thedifferent cellular functions.
Highmobility
Fast evasion intotissue[1]Rapid migration to the lymphnodes
Oftenhiding
Adcocksetal:CatechinsfromGreenTeainhibitbovineandhumanecartilageproteoglycanandType Icollagendegradationin vitro.J.Nutr.2002
Mar 132/3:341-6
30
Poor Immune Response
Our immune response consists ofan immediate non-specificpart= Innate immune response
An organized part with amemory= Adaptive immune response
31
INNATEIMMUNITY ADAPTIVEIMMUNITY Th &Th
1
2
Short upregulation of Cytokines throughmacrophages
32
Th1
intracellularimmunity
IL-2
IFN-gamma TNF-beta (IL-10)
Skogman, Barbro H., et al. “Adaptive and innate immune
responsive- ness to Borrelia burgdorferi sensu lato in exposed asymptomatic chil- dren and children with previous clini-53

cal Lyme borreliosis.” Clinical and Developmental Immunology
2012(2011).
Widhe, Mona, et al. “Borrelia-specific interferon-γ and interleukin-4 secretion in cerebrospinal fluid and blood during Lymeborreliosis in humans: association with clinical outcome.” Journal of Infectious Dis- eases 189.10 (2004):1881-1891.
Strle, Klemen, et al. “Elevated levels of IL-23 in a subset ofpatients with post–Lyme disease symptoms following erythema migrans.” Clin- ical infectious diseases 58.3 (2013):372-380.
Hansen, Emily S., et al. “Interleukin-10 (IL-10) inhibits Borrelia burg- dorferi-induced IL-17 production and attenuates
IL-17-mediated Lyme arthritis.” Infection and immunity 81.12(2013):4421-4430.
Jarefors, Sara, et al. “Lyme borreliosis reinfection: might it beexplained by a gender difference in immune response?.” Immunology 118.2 (2006):224-235.
Treg immune tolerance regulation of immune response
33
High Th1 – associated res- ponses correlated with more effective immune – mediated spirochetal killing
Supportive measures to Treg downregulate Th17(IL-17)
34
What more causative issues can disrupt our immune system
and make us more susceptible for development of a chronic(multi-) infectious pathology?
heavy metal toxicity & pollution Th17↗
35
TH17Role against extracellular pathogens, fungi and yeast
Recruits macrophages and neutrophils to infectedtissue
Helps to maintain mucosal barrier(intestine)
36
What is the contribution of Th17 in the development of autoimmunity after exposure to heavy metals?
When NAIVE CD4 cells are exposed to TGF beta , IL-6,IL-21 &IL-23 …Th17 cells are differentiated
Probably the protective Th17 are induced by IL-6 & TGF beta
Neutrophils and macrophages are recruited for host defense(pathogen clearance) against extracellular bacteria and fungi at
mucosal sites to eliminate the infection and maintain barrierfunction
Mucosal surfaces are constantly exposed to foreign material
and the a protect is “immune surveillance” -this is carried out
by severalmechanis!!!!otherimportantmechanismsforhostdefenseatintestinal
mucosal site are the generation of sIgA’s , IgE’s andIgG’s
The respiratory mucosa is constantly challenged with inhaled particulates and infectious agents = major port of entry
for infe diseases
38
Probably the damaging Th17 are induced by IL-23 & IL-1 beta
(probably IL-17a and or IL-17f andIL-22)
Some researchers have recently shown that IL-17A and/or IL17F are responsible for development of inflammation in many
disorders,
IL-2

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BOOK OF ABSTRACTS | 12th European Congress of Integrative Medicine · 1st International Symposium on Integrative Health and Education

IFN-gamma TNF-beta (IL-10)
Supresses
especially in autoimmune diseases like rheumatoid arthritis(RA), psoriasis, juvenile idiopathic arthritis (JIA), Crohn’sdisease
and many others
And IL-22 is a member of IL-10 cytokine family, which is linked
to chronic inflammation and participates in pathogenesis ofmany autoimmune diseases.
immune tolerance(Adami et al. 2014; Hot and Miossec 2011; Hu et al. 2011;
Piper et al. 2014; Tesmer et al. 2008).
What more causative issues can disrupt our immune system
and make us more susceptible for development of a chronic(multi-) infectious pathology?
4 is being produced in response tochitin
chitin is a sugar found in fungi, parasites and eco-skeleton – chitin is responsible for structural rigidity infungi, helminths and insects
IL-4 stimulates woundhealing macrophages to produce arginase, converting arginine into ornithine(collagenprecursor)=tissuerepair
IL-4 simulates woundhealing macrophages to produce chitinase, breaking down chitin structure andhelminths= elimination of helminths
IL-4 activates Th2 immune response +mastcells, basophils& eosinophils +IgE
IL-4 actually drives naïve Th0 cells intoTh2
lymphocytes and inhibits Th141
Th2 induced immunity impairs our Th1 response against intracellular infections=
consider treatment for helminths in all patients suffering from chronic infections orallergy
If stool tests are negative for parasites, patients do sufferfrom allergy or Th2 dominance
42
What more causative issues can disrupt our immune system
and make us more susceptible for development of a chronic(multi-) infectious pathology?
heavy metal toxicity & pollution Th17↗
allergy Th2↗
parasites Th2↗
poor sleep Natural Killer Cells↘
stress Th2↗
vaccination Th2↗
genderdifference?
Mold &Biotoxins
43
oftenresultsofwater-damagedbuildings/ moisture
our body is not able to remove thetoxins
unadapted immuneresponse→ Biotoxin accumulation→ Chronic inflammation ( CIRS)
44
Persistent Biotoxin Load
Continual activation of Cytokineresponse
Overactive innate immune system and dysfunctional adaptive immune system= Multi-Systemic disease syndrome
Dr Schoemaker45
Common misdiagnosis: Differentialdiagnosis
Often interaction with Lyme and viralinfections
Edmondson, David, et al. “Immune response among patients
exposed to molds.”
International journal of molecular sciences 10.12 (2009):54715484.
Brewer, Joseph, etal. “Detection of mycotoxins in patientswith chronic fatigue syndrome.” Toxins 5.4 (2013): 605-617.
Symptoms of moldtoxicity
Key Symptoms:
fatigue, weakness, sensitivity to light, blurred vision, Chronic
Sinus Congestion, Cough, Chest Pain,Joint Pain,
Cognitive impairment, skin sensitivity to touch, moodswings,
numbness, vertigo, etc
Unique or keynote symptoms:
Electrical shocks, Ice pick pains, Paresthesias,Internal vibration, tremor, Increased sensitivity to everything; mold makes
everything worse
Symptoms of Mold Toxicity : Mold and Mycotoxins = effects
on neurological and immune systems in humans Campbell,Thrasher, Gray , Vojdani -Advances in Applied Microbiology VOL
53,2004
46
Diagnosis:
Mycotoxin testing : urinary mycotoxin testing, IgG & IgE
serum antibodies
Indirect markers or tests : Visual contrast sensitivity, inflammatory markers (TGF beta1, MMP9, MSH, ADH, C4a,VEGF,VIP,…)47
Have developed resistance to 2 or more antibiotics and havethe capability to produce abiofilm
Resulting from the widespread use ofantibiotics
Common in CIRS resulting from the bidirectional relationshipbetween MSH andMarcons
MSH protects mucus membranes fromcolonization
MSH deficiency in CIRS eliminates the protective barrier andMarcons result.
48
Basics on mold treatment:
Removal fromexposure
Gut repair & diet &detox
Binders &Glutathione
Correct inflammation & immunebalance
49
Lyme or chronic multiple infections results from an unadapted immune response considering many factors can influenceand dysbalance Th1/Th2/Th17

BOOK OF ABSTRACTS | 12th European Congress of Integrative Medicine · 1st International Symposium on Integrative Health and Education

MODERN TESTING FOR LYME DISEASE
AND COINFECTIONS
Author, role and place: Armin Schwarzbach MD
PhD, Specialist for laboratory medicine, ArminLabs, Zirbelstrasse 58, Augsburg, Germany
Abstract: Lyme disease is caused by spirochete Borrelia burgdorferi,transmitted dominantly by tick-bites. Lyme disease and coinfections
are the chameleon of symptoms, laboratory tests and therapies.
The laboratory diagnosis of tick-borne diseases and other symptom-related chronic infections is based on indirect and direct laboratory tests for different kinds of bacteria.
In Lyme disease and coinfections there should be done modern laboratory testings based on antibodies and T-cellular immune responses. There is a lack of confidence in falsely established laboratory tests
for antibodies like the Borrelia ELISA against whole spirochete, which
are not standardized and often false negative. Diagnosing doctors
need better and improved laboratory tests, such as new Tickplex testing antibodies against round bodies (pleomorphic forms) of Borrelia
burgdorferi and testing for T-cellular immune responses by Elispot andCD57 cell count.
Key words: Lyme disease, Borrelia burgdorferi, spirochete, roundbodies, coinfections, coinfections-checklist, Tickplex, Elispot, CD57cell
count
Article: Ticks are contaminated with Borrelia burgdorferi and otherbacteria like Ehrlichia/Anaplasma, Rickettsia, Babesia and Bartonella.
Borrelia burgdorferi is the most common tick borne disease and named as the “chameleon” of symptoms, because it can be the reason
for many symptoms like fatique, neck-pain, headache, short term memory loss, burning hand or feet, numbness, joint pain, muscle pain,
muscle weakness, psychiatric symptoms like depression or panic attacks.
Many patients with tick-borne diseases are infected by different
coinfections (“multiple infections”). Most symptoms of tick-borne
diseases are not high-specific for Lyme disease or one of the othertick-borne diseases (“overlapping symptoms”).
Therefore, medical doctors should check all symptoms by a modern
and digitalized coinfections-checklist to get an individual clinical “ranking” of possible coinfections.
In bacterial infections with Lyme disease and coinfections there
should be immune responses based on antibodies and T-cells. Thereis a lack of confidence in falsely established laboratory tests for antibodies like the Borrelia ELISA, which are not standardized and often false
negative because just testing whole spirochete antigens. Diagnosing
doctors need better and improved laboratory tests, such as new Tickplex for testing Borrelia burgdorferi round bodies antibodies (pleomorphic, persister forms) and testing for T-cellular immune responses
by Elispot and CD57 cells.
Borrelia burgdorferi is well known as a spirochete, but can develop
round bodies, which are atypical forms with double cell wall. Therefore, round bodies of Borrelia burgdorferi should be taken into consideration as being clinically relevant and influence the development ofnovel diagnostics and treatment protocols.
Tickplex is analysing by ELISA method antibodies against roundbodies of Borrelia burgdorferi beneath antigens from whole Borrelia burgdorferi spirochete. There is much higher sensitivity by testing

55

against round bodies antibodies, reaching 95% in comparison withconventional Borrelia burgdorferi ELISA antibody testing just against
antigens from the whole spirochete. Elispot reflects the current Borrelia burgdorferi activity of chronic and recent Borrelia burgdorferi
infections. It is highly sensitive and can detect even one single Borrelia
burgdorferi- reactive T-cell in the sample. With detection levels thatcan be as low as one cell in 100,000, this test is one of the most sensitive cellular assays available. The Elispot is between 20 and 200 times
more sensitive than a conventional ELISA. Elispot is named the new
T-Cell Test is a “Game Changer” for Lyme disease: The sensitivity of
ELISPOT is estimated at 84%, and the specificity is 94%. Elispot assays
provide robust, highly reproducible data and can be retested for theacquisition of additional information in follow-up assay.
Clinical research studies and case studies have shown that chronic
Lyme infections are often accompanied by changes in the cellularimmune defence. Evidence for this is a decreased number of naturalkiller cells (NK/CD3-CD56+), in particular, a decreased absolute number of activated NK cells (CD3-CD56+CD57+). While acute Borrelia
burgdorferi infections and other diseases show normal CD57+ parameters, chronic Lyme patients often have less than 100 CD57+
cells/µl. According to scientific studies, a suppressed absolute
number of CD57+ cells has mainly been observed in patients withneurological symptoms, rather than in patients whose tissue orskeleton system had been affected. A decrease of CD57+ cells canpersist until an improvement in symptoms is achieved with theuse antibiotic and other treatment forms. In reverse, a decreased
CD57+ parameter is seen as a measurable signal for an active chronic Borrelia infection and can be a possible indicator for a successful therapy. Elispot and CD57 cell count) complement each other inthe quest to understand T cell-mediated immunity in vivo.
References:
Diagnostik und Therapie der Lyme Borreliose, Deutsche Borreliose
Gesellschaft e.V., Stand2008
Advance Topics in Lyme Disease, J.J. Burrascano JR., M.D., International Lyme and Associated Diseases Society, 16thEdition, October2008
V.von Baehr et al., Untersuchungen zur diagnostischen Wertigkeit
des Lymphozytentransformationstestes bei Patienten mit Borreliose. J.
Lab. Med. 31 (3)(2007149-158
E. Valentine-Thona et al. A Novel lymphocyte transformation test for
Lyme borreliosis, Diagnostic Microbiology and Infectious Diseases, Volume 57, Issue 1 (2006)27-34
Anthony DD, Lehman PV. T-cell epitope mapping using the Elispot
approach. Methods 2003; 29: 260-9
M. Widhe et al. T-Cell epitope Mapping of the Borrelia garinii Outer
Surface Protein A in Lyme Neuroborreliosis. Scandinavian Journal of Immunology 70,141-148
R.B. Stricker et al. Decreased CD57 lymphocyte subset in patientswith chronic Lyme disease. Immunology Letters 76; 43-48(2001)
R.B.Strickeretal.LongtermdecreaseintheCD57lymphocytesubsetinapatientwithchronicLyme disease. Ann Agric Enviro Med 9; 111113(2002)
Skogman et al. Adaptive and Innate Immune Responsiveness to Borrelia burgdorferi sensulato
in Exposed Asymptomatic Children and Children with Previous Clinical Lyme Borreliosis, Clinical and Development Immunology,Vol. 2012,
Article ID 294587, 10 pages
CenterforDiseaseControlandPrevention.UpdatedGuidelinesforUsingInterferonGammaRelease Assays to Detect Mycobacterium tuberculosis Infection, United States. MMWR 2010; 59 (No.RR-5) http://www.

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BOOK OF ABSTRACTS | 12th European Congress of Integrative Medicine · 1st International Symposium on Integrative Health and Education

cdc.gov/mmwr/pdf/rr/rr5905.pdf
Lehman PV et al.: Unique Strengths of ELISPOT for T Cell Diagnostics
in: Kalyuzhny AE. Handbook ofELISPOT:
Methods and Protocols, Methods in Molecular Biology, Vol. 792.
2ndEd: Springer; 2012: 3-23
K. Garg et al. Evaluating polymicrobial immune responses in patients
suffering from tick-borne diseases, Scientific reports(2018)8:15932
Merilainen L., Herranen A., Schwarzbach A., Gilbert L. Morphologicaland biochemical featuresof
B.b. pleomorphic forms, Microbiology, published online ahead ofprint January 6, 2015
MerilainenL.,BrandnerH.,Herranen,A.,SchwarzbachA.,GilbertL.PleomorphicformsofBorrelia burgdorferi induce distinct immune responses,
Elsevier Microbes and Infection 18 (2016)484-495

MUSIC, SCIENCE AND MEDICINE
Jordi A. Jauset, Ph.D. Barcelona
Music has been part of social events and religious rituals since ancient times. It has also been usedasatherapeuticmeansbybothshamansandancientpriestsinEgyptiantemples,placesof
prayer and, at the same time,healing.
Until a few decades ago, the use of sound and music toimprove health was considered para- scientificoresotericbecausetherewasnoscientificevidenceontheeffectsproducedthatcould be “measured” and/or quantified. The appearance
and evolution of neuro-imaging techniques allowed us to investigate and observe the changes that occur inside the brain
when a subject performs or thinks about “music”. This wasa great boost for musical research, for both simple musicalinterventions and those performed by professional musictherapists.
The first “medical” writing about the use of music in medicine
appeared in the nineteenth century.Itsphysiologicaleffectsweremeasured,suchaschangesinheartrate,respiratoryrate andblood pressure, which were simple measurements that used
the means available at that time. Today, the response to music can be measured through various peripheral biomarkers(cortisol,immunoglobulinA,oxytocin...),itseffectonthereleaseofdifferentneurotransmitters, and other means. This helps
explain how listening to and/or performing music affects brain
biochemistry and shows its role in improving quality of life.
In turn, Cochrane international scientific reviews confirm thatmusic therapy alongside conventional medical treatments
offers better results than conventional treatmentalone.
Inmypresentation,
Iwillexplainthebasesorscientificclaimsthatallowustoarguewhysound and music are useful as complementary therapies for improving quality oflife.
Correspondence: jjauset@jordijauset.es
References:
Guetin S. et al. (2012). The effects of music intervention in the management of chronic pain: a single-blind,randomized, controlled trial. Clin J Pain May,28(4),32937. doi: 10.1097/AJP.0b013e31822be973.
Jauset-Berrocal, J.A. (2013). Cerebro y música, una pareja saludable. El Ejido (Almería): Circulo Rojo.
Koshimori,Y.&Thaut,M.(2018).Futureperspective-

sonneuralmechanismsunderlyingrhythm
andmusic based neurorehabilitation in Parkinson’s disease.
Ageing Research Reviews, 47,133- 139.doi:10.1016/j.
arr.2018.07.001.
Kreutz, G. (2014). Does singing facilitate social bonding? Music&Medicine, 6(2) ,51-60.
Radiological Society of North America. (2016). Musicaltraining creates new brain connections in
c h i l dren.
ScienceDaily.
RetrievedJuly
5, 2019
fromwww.sciencedaily.com/releases/2016/11/161121180403.htm.
Singer, A. et al. (2018) Non-invasive 40 Hz light flicker to reduce amyloid load and recruit microglia. Nature Proto, 13, 1850–1868), doi: 10.1038/s41596-0180021-x.

INTEGRAL APPROACH OF THE PACIENT
THROUGH THE KINESIOLOGY
Miguel Angel Amézaga López
Physiotherapist ,kinesiologist and osteopath C. O.
Physiotherapist and founding partner of Arjuna Center ofTortosa( Integrative Health Center)
Physiotherapist of Amposta Comarcal Hospital.
Key words (kinesiology, testing , art, priority, communication, neutrality,
respect, humility, accuracy).
Kinesiology is a really effective and practical tool to any health professional who incorporates it in his therapeutic approach. It gives us thepossibility to be more accurate in both the diagnostic and the treatment
approach, where respect for what the testing indicates is one of the mostimportant premises. During the session,neutrality is a key factor becauseof the communication with the patient through the corporal answers toourquestions.
Testing is an art and it requires practice to acquire skills, confidence andself-assurance. It is done in different ways: the most commonly used are
the muscular test and AR (arm reflex). A kinesiologist defined Kinesiology
as “The Science of the Consciousness”, because the result and information that weget throught he test help the patient to be more aware of
aspects he didn’t know which are related with his health’sbalance.
During the session, there is an entry protocol, then four ambits will betested: the energetic, emotional, metabolic-chemical and structural one,taking into account a crucial aspect, the respect for the process that thepatient needs. That is, for example, if the patient visits us to treat an anxiety problem, the logic may indicate to us to balance his emotional field, but
the testing may indicate that we should address the biochemical -metabolic field. Let’s respect then the result, because probably the patient isstill not ready to tackle his emotional sphere, unless he has his metabolic
ambit balanced before.
In summary, this is what, in kinesiology, is known as “priority concept”,
which helps us to identify which field or fields are the most importantones to treat on the patient every moment. In the example previously
described, the patient will be treated, most certainly, on his emotional
sphere in following sessions, once we have balanced the biochemical andmetabolicfield.
Therefore, the humility of the therapist is based on be in gat the serviceof the patient,respecting his process and providing him with an accompaniment for him to take also responsibility in his health with the infor-

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mation provided by the test. In many occasions, the kinesiologist acts as abridge and refers the patient to another professional when needed. Thus,
the multidisciplinary support is part of his clinicalpractice.
Finally, it should be pointed out that the more knowledge and experience the kinesiologis t has on each field, the most accurate, complete andcomprehensive his therapeutic approach willbe.
BIBLIOGRAPHY:
Practical Manual on Kinesiology (Jean Claude Guyard) Kinesiology (Mariano
Martin)Touch for Health (Dr. Jhon Thie)
BrainGym, Learning of the whole brain(Dr. Paul E. Denninson, Gail E. Denninson)) Practical Professional Kinesiology (Bruce Dewe)
Tree in one (Dr. Gordon)
Scientific base of the human movement (Luttgens& Wells)
Appliend kinesiology ( a fast and safe method for health and healing) (Tomy Carol Valentine)

IN RESONANCE WITH THE BODY
Jacomina Kistemaker, psychologist and sound‐
workerFounder and director of Center Punta de Cousoand pioneer of the use of sound for Personal andspiritual development in Spsin since`95.
Vibration is the essence of life. Every cell and part of our bodyhas its own frequency and sound. The form and shape of ourbody, our emotions, our mind and soul, our whole being is theresult of a symphony of tones, specific for each and every being.
The original frequencies change in the parts that are out ofbalance. One could say the body gets out of tune. Like everythingin nature, the body will use anything available to restore the balance, to tune the system. Memories of what has happened to us
on a physical as well as emotional level gets stored in our bodies
in the form a crystal structures. It depends on the kind of experiences where these memories get stored.
When we work with sound or with the voice, the body uses
the frequencies of sound to rebalance itself, through resonance.
Because the body is constructed from an enormous amount ofinterconnected frequencies, it’s important to work with instruments or a voice rich in harmonics. Tibetan singing bowls, monochords, gongs and the voice are wide array of harmonic sounds
and have an easy access because they vibrate according to thesame harmonic laws as the body. The voice is the most powerful of all to get deep into the body with its vibrations, especiallywhen we train it to function as a vibrational instrument, able toresonate with every system or part of thebody.
To train the voice as a vibrational healing instrument one has
toopen the ear to hear more frequencies. We can not makesounds we can not hear.
We also have to learn how to relax to voice, especially the larynx and the trachea to be able to make the sounds and vibrations
resonating with the specific parts or structures of the body, torelax the body. The more we relax the richer the voice gets withharmonics.
On a more advanced level one also learns to tune into theenergy field of oneself or others to reconnect with the natural

57

healing powers of thebody.
To get a direct experience of this very effective and easy tolearn healing techniques we will explore the use of the voice inrelation to the ear, the larynx, the trachea and the bone‐structure of the body in combination with the visual representations ofthese parts of thebody.
It’s not necessary to have a good voice, good ear or musicalknowledge. We sing for and into our own bodies, for nobody elsein this very private and intimate exploration of our bodies. Doingso our voices open up and start “singing” by itself in harmony
and resonance with our “felt anatomy”.

EFFECTS OF CHI KONG ON HEALTH
Garcia, D. PhD, fisioterapeuta y enfermero, (Madrid/SP)
Qigong is defined as the skill of body-mind exercise that integrates
the three adjustments of body, breath, and mind into “one”. Qi means
vital life-energy that flows thru energy channels (meridian system) of
body, and Gong means practice or skill.
It is a combination of static stance, dynamic gentle physica lexercises, care of body posture, a meditative state of mind, rhythmic breathing techniques than provides, with regular practice,a body relaxation and mind calm. With long-termpracticing, qi gong can improvehealth on different aspects including quality of life, mental health,sleep quality cardiovascular parameters, balance, cardiorespiratory
physical performance, osteoarthritis and flexibility. In addition, somesystematic reviews have found benefits for specific health problems,
including type 2 diabetes, pain relief, hypertension and blood lipidmetabolism.

“REIKI AS COMPLEMENTARY THERAPY.”
Author:Ana Belén Fernández Cervilla
Role and workplace:
Associate professor in the Faculty of Medicine and
Health Sciences. School of Nursing of the University of Barcelona (UB).
Director and professor of the Master of Own Title
Autonomous Interventions Complementary nursing care of the UB.
Member of the Natural Therapies Committee of
the Official College of Nurses and Nurses of Barcelona (COIB).
ABSTRACT:
Nurses consider Natural and Complementary Therapies, therapeutic activities, non- aggressive interventions, that preferably use natural means such as air, water, soil, plants, exercise and diet.
The hands, mind and the therapist’s own presence are also usedin the client’s own mental self-control mechanisms, directing energy,

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BOOK OF ABSTRACTS | 12th European Congress of Integrative Medicine · 1st International Symposium on Integrative Health and Education

strength and positive thinking.
The Official College of Nurses of Barcelona (COIB) adapted thecategories of natural and complementarytherapiestothereportsoftheWhiteHouseCommissiononComplementary andAlternativeMedicinePolicyandtheNationalCenterforComplementaryandAlternative
Medicine(NCCAM),proposingfivecategories(1).Thisare1.Alternativemedicalsystems.
2. Mind-body interventions. 3. Biologically based therapies.4. Manual therapies. 5. Energy- based therapies.
Energy-based therapies are based on the manipulation of energy
fields.
Theyincludethosethataffecttheenergyfieldsthatenvelopthehumanbodyandpenetrate it, such as those involving the unconventional useof electromagnetic fields and alternating current fields(1).
The Japanese Mikao Usui was the rediscoverer of the Reiki.
ReikiisanOrientalwordthatiscredited/attributedwiththemeaningofuniversalvitalenergy. The prefix “Rei” is the vital energy of theuniverse, the essence of cosmic energy that permeatesallthingsandsurroundsallplaces.Thesuffix”ki”isconsideredthebasicenergy, the life
force on which our livesdepend.
Reiki is trained on three levels The first level is learned to perform
autoreiki and perform therapytoothers.InthesecondlevelitistaughttoperformReikiremotely.Andonthethird level starts mastery(2,3).
Reiki treatment is performed with a hand imposition on the chakras.
Chakras are energy centers found in the human body and have thefunction of energizing it. Although there are numerous chakras in thebody, the most important are seven that are distributed in trunk andhead.Eachmainchakraisassociatedwithamainnerveplexusandanendocrinegland. The 1st chakra the base is related to the adrenal glands,
the 2nd of the pubic center with ovaries and testicles, the 3rd chakra
the solar plexus with the pancreas, the 4th chakra or heart with thethymus gland, the 5 chakra the one with the thyroid gland, the 6th
chakrathe third eye with the pituitary gland and the 7th chakra thecrown with the pineal gland(4).
Reiki has been recognized by OMS as a TC since 1995 as well as
by NCCAM, which is under the National Institutes of Health (NIH) of
the United States and the COIB seen including Reiki in the category ofEnergy-Based Therapies.
In 2013 it was introduced as a Classification of Nurse Interventions
NIC1520,defining it as: “Using a specific sequence of hand positions
and symbols to channel universal life force in order to recharge, realign and rebalance the human energy field (5).”There are 3 ways through which Reiki is being incorporated into
conventional care in the healthcare system. The 1st is through thehealth workers who are learning the 1st level of Reiki, using it for
self-care and integrating this comforting touch into routine care. The
2nd by Reiki practitioners who are offering treatment to patients andstaff. And finally the education programs performed in hospitals thatare teaching the first level of Reiki to patients, caregivers, and family
members (3).
The scientific evidence found points to results in which the effectof Reiki is not evidentand thoseiftheeffectisevident.AsfortheresultswithevidenceoftheeffectofReikithestudies show benefits for both nurses and patients(6).
In relation to studies that the effect of Reiki is not evident, most ofthem do not have statistically significant results (7).
Concerning the studies in which if the effect with benefits for thenurses is evidenced, we find that:In the study of Salome (8), nurses after receiving Reiki presented agreater balance: physical, mental, emotional and spiritual, and a harmonious relationship with their environment, in addition to greater
self-knowledge.
In the study by Raingruber and Robinson (9) the nurses after the
Reiki sessions felt more relaxed, more conscious and with greater capacity for solving problems.
In the Brathovde study (10) the nurses expressed the changes intheir own perception of their caring behaviors.
Moststudieswithbeneficialresultsforpatientshavebeenperformedinthefieldofoncology showing an improvement in the side effects ofchemotherapy (11-13) and radiotherapy and relief of symptoms (11).
Specifically, the results obtained in the different studiesare:a)Thatfatiguedecreases(11,13,14),pain(11-19),anxiety(11,14-16,18,20),stress(18,20),
bloodpressure(18,20),temperature(20),avoidsadditionalmedication(21),decreases
vomiting (15) and nausea (13) and hospital stay (16).
b) Increases relaxation (14-16,20,22), immunoglobulin A in saliva(20), helps the healing process (12), increases the feeling of well-being (14,15,19) and improves the quality of the sleep(14,16).Itimprovesmood(16),increasesvitality(13),changesinattitudeandlifestyle (23),increases the quality of life (11,16), the sensation of heat (16) and increases defense cells (18).
There are also other investigations in study populations different
from that of oncological patients, with a decrease in HR, RF and TA(21,24,25), such as Hulse (21) that studies patients who are goingto perform an endoscopy, in Merati (26) and collaborators there is adecrease in migraine and its severity, as well as a decrease in workabsences in patients with migraine. And in the studies of Ávila (27,28)
there is evidence of a greater control of glucose and cholesterol in patients with type 2 diabetes mellitus.
However,onlyonestudyhasbeenfoundthatlinksReikiwithhighbloodpressure.Thestudy by Fortes Salles (29) shows a decrease in bloodpressure in those patients with hypertensionwhohadreceived1sessionofReiki.Anditsuggeststheneedtocontinue investigating this topic
in the hypertensive population due to the scarcity of studies withanalytical or experimental designs.
Keywords:
Reiki, complementary therapy, nurse intervention.
References:
López Ruiz J, Arqué Blanco M. Bases per a l’acreditació de la competència
dels professionals infermers en Teràpies naturals i complemtàries. [Internet]. Barcelona: Col · legi Oficial d ’ Infermeres i Infermers de Barcelona;
2009 [cited 2015 Jan 8].p.
20. Available from: http://www.coib.cat/uploadsBO/Generica/Documents/BASESPER A L’ACREDITACID DOC JDLIA LDPEZ.PDF
Rowland R, Carrasco A. Manual de Reiki 1. Asociación Española de Terapias Complementarias Causay.; 2010.
Miles P, True G. Reiki--review of a biofield therapy history, theory, practice, and research. Altern Ther Heal Med [Internet]. 2003 [cited 2016 Jul29];Mar-Apr;9(2):62–
72. Available from: http://www.ncbi.nlm.nih.gov/pubmed/12652885
Versyp T. La Dimensión cuántica: de la física cuántica a la conciencia[Internet]. [S.l.] : la autora; 2005 [cited 2015 Jan 8]. Available from:http://
cataleg.ub.edu/record=b1802202~S1*cat
NIC [1520] Reiki [Internet]. 2013 [cited 2016 Jan 12]. p. 2013. Available
from:http://www.nnnconsult.com/nic/1520
Fernández-Cervilla AB. Eficacia del Reiki sobre la regularización de la ten-

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sión arterial en personas con hipertensión arterial [Internet]. Universidad
de Barcelona; 2017. Available from:http://hdl.handle.net/10803/457141
Fernández Cervilla AB. Eficacia del Reiki sobre la regularización de la tensión arterial en personas con hipertensión arterial. TDX (Tesis Dr en Xarxa)[Internet]. 2018 Jul 21 [cited 2017 Nov 24]; Available from:http://www.tdx.
cat/handle/10803/457141
Salomé M. Sentimentos vivenciados pelos profissionais de enfermagem que atuam em Unidade Terapia Intensiva após aplicação do Reiki. Rev
Saúde Coletiva [Internet]. 2009 [cited 2014 Nov 13];6(28):54–8. Available
from:http://www.researchgate.net/publication/40424604_Sentimentos_
vivenciados_pelos_profissionais_de_enfermagem_que_atuam_em_Unidade_Terapia_Intensiva_aps_ aplicao_do_Reiki/file/3deec52657f2227053.pdf
Raingruber B, Robinson C. The effectiveness of Tai Chi, yoga, meditation,
and Reiki healing sessions in promoting health and enhancing problem solving abilities of registered nurses. Issues Ment Health Nurs [Internet]. 2007
Oct [cited 2014 Oct 10];28(10):1141–55. Available from:http://www.ncbi.
nlm.nih.gov/pubmed/17957554
Brathovde A. A Pilot Study. Reiki for Self Care of Nurses and Healthcare Providers. Holist Nurs Pract [Internet]. 2006 Mar [cited 2005 Aug
16];20(2):95–101. Available from:http://content.wkhealth.com/linkback/openurl?sid=WKPTLP:landingpage&an=00004650-200603000-00010
Tsang KL, Carlson LE, Olson K. Pilot crossover trial of Reiki versus rest fortreating cancer-related fatigue. Integr cancer ther [Internet]. 2007 Mar [cited 2014Nov
25];6(1):25–35. Available from: http://www.ncbi.nlm.nih.gov/pubmed/17351024
Olson K, Hanson J, Michaud M. A phase II trial of reiki for the management of pain in advanced cancer patients. J Pain Symptom Manage [Internet]. 2003 Nov [cited 2014 Oct 15];26(5):990–7. Available from:http://linkinghub.elsevier.com/retrieve/pii/S0885392403003348
Scandrett Hibdon S. Biofield Considerations in Cancer Treatment. Semin
Oncol Nurs. 2005;21(3):196–200.
Bricco N, Guillame C, Storto S, Ritorto G, Catino C, Gir N, et al. The effects
of reiki therapy on pain and anxiety in patients attending a day oncology
and infusion services unit. Am J Hosp Palliat Care.2012;29(4):290–4.
Vitale M, Grassa M La, Lombardi F, Cova D, Cofrancesco E. Il Reiki nell’assistenza infermieristica al paziente anziano con neoplasia avanzata. oncologica[Internet]. 2005 [cited 2014 Nov 13];5(3):54–9. Available from:http://www.
dacuoreacuore.it/e107_files/downloads/Autunno05_pag_54_59.pdf
Maza Muela B. Beneficios percibidos de la aplicación de la terapia Reiki en pacientes oncohematológicos. Metas … [Internet]. 2010 [cited 2015
Jan9];13(3):6–
12. Available from: https://medes.com/publication/58298
Shan S, Yu J, Qin Y. Terapias de Toque para el alivio del dolor en adultos. Bibl Cochrane Plus [Internet]. 2011 [cited 2015 Jan 9];1. Available
from:http://www.bibliotecacochrane.com/BCPGetDocument.asp?SessionID=10945384&DocumentID=CD006535
Freitas de Moura VL, Andrade A De, Rossato Badke M. El Reiki como
forma terapéutica en el cuidado de la salud: una revisión narrativa dela literatura. Metas de enfermería [Internet]. 2015 [cited 2016 Aug
8];14(1):335–56. Available from:http://dialnet.unirioja.es/servlet/articulo?codigo=5044727&orden=0&info=link%5Cnhttp://dialnet.unirioja.es/
servlet/extart?codigo=5044727%5Cnhttp://dialnet.unirioja.es/servlet/extart?codigo=4971325
Catlin A, Taylor-Ford RL. Investigation of standard care versus sham Reikiplacebo versus actual Reiki therapy to enhance comfort and well-being ina chemotherapy infusion center. Oncol Nurs Forum [Internet]. 2011 May[cited 2015 Jan 16];38(3):E212-20. Available from:http://www.ncbi.nlm.
nih.gov/pubmed/21531671

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Wind Wardell D, Engebretson J. Biological correlates of Reiki Touchsm
healing. J Adv Nurs [Internet]. 2001 Feb 28 [cited 2014 Nov 13];33(4):439–
45. Available from:http://onlinelibrary.wiley.com/doi/10.1046/j.13652648.2001.01691.x/full
Hulse, RS; Stuart-Shor ER. Endoscopic procedure with a modified Reiki
intervention: a pilot study. Gastroenterol Nurs [Internet]. 2010 [cited 2014
Nov 25];33(1):20–6. Available from:http://journals.lww.com/gastroenterologynursing/Abstract/2010/01000/Endoscopic_Procedure_With_a_Modified_Reiki.3.aspx
Maza Muela B, Chao Lozano C. Estudio de los beneficios de la aplicaciónde la terapia reiki en pacientes oncohematológicos. Metas Enferm [Internet]. 2010 [cited 2014 Oct 15];13(3):6–12. Available from:http://www.congresoseeo.org/pages/comunicaciones/ponencias/119.pdf.
Santos A. O cuidado tridimensional através do Reiki e florais de Bachnuma unidade básica de saúde [Internet]. Florianópolis (SC): Escola de Enfermagem da Universidade Federal de Santa Catarina.; 2005 [cited 2014
Dec 15]. Available from:http://www.sbpcnet.org.br/livro/58ra/SENIOR/RESUMOS/resumo_1463.html
Mackay N, Hansen S, McFarlane O. Autonomic nervous system changes
during Reiki treatment: a preliminary study. J Altern Complement Med[Internet]. 2004 Dec [cited 2014 Nov 13];10(6):1077–81. Available from:http://www.ncbi.nlm.nih.gov/pubmed/15674004
Baldwin AL, Wagers C, Schwartz GE. Reiki improves heart rate homeostasisinlaboratory rats. J Altern Complement Med [Internet]. 2008 May [cited
2014 Oct 15];14(4):417–22. Available from: http://www.ncbi.nlm.nih.gov/
pubmed/18435597
Merati L, Brianzoli C, Barbagelata F. Le tecniche di rilassamento come trattamento integrativo nella cura del dolore : Reiki e terapia dell ’ emicrania.
dacuoreacuore.it [Internet]. 2010 [cited 2014 Nov 13];(7):7–9. Available
from:http://www.dacuoreacuore.it/e107_files/downloads/Le tecnichedirilassamento pdf
Avila G, Casique L, Ávila-Sansores G, Casique-Casique L. Influencia del
Reiki como Cuidado de Enfermería en el Bienestar de Personas con Diabetes. Desarro Científico Enferm.2009;17(2):57–61.
Ávila-Sansores G, Ávila Sansores GM. Efecto del Reiki como cuidado deenfermería en el control metabólico de diabéticos tipo 2. Rev Enferm InstMex [Internet]. 2010 [cited 2015 Jan 9];18(2):75–80. Available from: http://
www.medigraphic.com/pdfs/enfermeriaimss/eim-2010/eim102c.pdf
Fortes Salles L, Vannucci L, Salles A, Paes da Silva M. The effect of Reiki on blood hypertension. Acta Paul … [Internet]. 2014 [cited 2015 Jan
14];27(5):479–84. Available from: http://www.scielo.br/article_plus.
php?pid=S0103-21002014000500014&tlng=pt&lng=en

CONTRIBUTIONS AND INSIGHTS FROMMEDICAL GEOLOGYElena Giménez-Forcada
Geological Survey of Spain, IGMEInternational Medical Geology Association, Spanish Chapter (IMGA-España)
e.gimenez@igme.es
As science advances, new lines of research are gradually opening
up that require cooperation across multiple disciplines. Medical Geology is an example of this since it proposes collaboration between two
broad fields of knowledge that initially appear to be unrelated, namely Earth Sciences and Biomedical Sciences (Centeno et al., 2016).

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Decades of research have shown that contact with our natural environment positively impacts on our health and cognitive functions.
However, exposure can also give rise to possible adverse effects on
health, both in humans and animals. In the latter respect, we are talking about natural geological processes, such as the generation andmobilisation of dust particles, earthquakes or volcanic emissions, orother examples such as dietary deficiencies in elements essentialforlife,orthequalityofgroundwater.Determiningtheimpactofsuchphenomenaon public health in order to offer sustainable solutions to these
problems involves advancing interdisciplinary cooperation between
Earth Sciences and Medical or HealthSciences.
Medical Geology studies the relationship between Geology (geological materials and processes) and Health (human and animal) inorder to understand the effects of geology on public health and better
define the laws that regulate the geographical distribution of healthconditions influenced by the natural environment.
In the past, the term Medical Geology was considered to be a synonym for Geographical Medicine, which was conceived as a branchof medicine that used geographical and cartographical methods todisplay its medical outcomes. Possibly the first study to make reference to this approach was by John Snow (1813-1858), an English
doctor considered by many to be the father of modern epidemiology. Successive outbreaks of cholera in London promptedhimtorelatethemtotheconsumptionofcontaminateddrinkingwater,ashestudied
thediseasefromaviewpointofLondon’spopulationasawholeandrelatedthistowatersupply. In this exploration of cause and effect, Snow developed the methodological tools of modern epidemiology throughdata surveys and the analysis of spatial distribution (in Giménez-Forcada and Salvador-Delgado,2019).
The pioneering work of Låg y Bølviken (1974) played an importantpart in the developmentofmodernMedicalGeology.Theyidentifiedhowleadpoisoningoccurredinareas overlying deposits of galena (PbS).
Feeding rabbits with plants grown over these galena soils, after fourweeks, they noted increases in the lead content in the liver, kidneys
and bones of these animals. It was also Låg (1990) who coined theterm Geomedicine, as the science relating ordinary environmental
factors to the geographical distribution of health problems in humans
and livestock. The term Geological Medicine was adopted at the endof the twentieth century. The manual Essentials of Medical Geology,
edited by Selinus et al. (2005) summarises the development of thisfield of knowledge known today as MedicalGeology.
Medical Geology occupied a special place in the International Yearof Planet Earth, the United Nations declaration to increase awarenessof the importance of Earth sciences for the advancement of sustainable development. According to Mulder (2008), this declaration sought
to improve the quality of life of the peoples of the world and at thesame time safeguard the variousnaturalenvironmentsthatexistonEarth.Italsoaspiredtoachievingthesustainableuse
1 of groundwater, considering rocks as holding a record of past
climate on Earth; it expressed a commitment to the sustainable useof natural resources, talking about sustainable mega-cities. It discussed the Earth from the core to the crust, considering the land surface
and soils as the living skin of the planet, and it dealt with life on Earthfrom the starting point of biodiversity. In the2008declaration,thevisionofGeologywasofascienceplacedattheserviceofafairerand more sustainable humanity. And it emphasized its role in building healthier, safer and more economically viable societies (Earth Science forSociety).
Medical Geology shows that Life is underpinned by the Earth; that
the Earth defines and controls the basis of our quality of life. It tries

to explain that certain health problems in a populationcanberelatedtothegeologicalenvironmentthatitinhabits,sincethegeologyofan
areaisthefoundationofthewholenaturalenvironment,includinghumanbeings.However,the geology of the area in which we live is scarcely understood. Much emphasis is placed on how Man impacts andpollutes the natural environment, especially our capacity to litter the
Earth with pollutants. Perhaps we also need to take into account thenatural environment conditions per se, that not everything that isnatural – simply by virtue of being natural – is good for our health,and that Man bears the responsibility for relating appropriately to theenvironment around us. But an appropriate relationship first requiresthat we understand the environment and, by the same token, publichealth should be evaluated based on a fundamental knowledge of theenvironment that both the current generation and their forebearers
haveinhabited.
Rocks and minerals are literally the bedrock, the foundation of theplanet and contain mostoftheknownchemicalelements.Someoftheseelementsareessentialforthegoodhealth of plants, animals and humans. Living beings acquire these elements fundamentally by means
ofthemediathatdevelopfromtherocks:air, groundwaterandsoil.Throughvariousprocesses of weathering, the rocks break down to form thesoils in which the plants are grown and on which animals live. Groundwater travels through soils, sediments and rocks as part of the hydrologicalcycle,whilemuchofthedustandgasescontainedintheatmosphereareofnatural origin. Hence, through the intake of food and wateralong the food chain and through the inhalation of dust and atmospheric gases, our health is directly related to the Geology around us.
All this is especially significant in rural areas. The conditions developedin the large cities correspond to an urban environment that is distinct
from the natural one but, nonetheless, composed largely of materials
of geologicalorigin.
The clearest example of the relationship between Geology and
Health occurs when an elementthatisvitalforlifeoccursinconcentrationstoolowortoohighinagivenenvironment, or when a non-essential
element occurs in potentially toxic concentrations. This geochemical
characteristic explains how diseases endemic to certain geographicallocations around the planet are linked to a deficiency or an excess ofa certainelement.
If we ask how we have come to consider that Geology is a key factor in the outbreak of certain diseases, we can see that mapping theincidence of certain endemic diseases has demonstrated that there
are significant differences from one place to another that can not beeasily explained by genetic traits, social differences or dietary diversity. When polluting influences are also ruled out, geology assumes afundamental importance, even if it is difficult topinpointaclearassociationofcauseandeffect.Inthisrespect,Daviesetal.(2005)establishedthat, for any comparison between Geology and Health to be possible,
two conditions must be met:(i)demonstrationofapathwaybetweenthesourceandthephysiologicaldamageitcauses: a clear nexus from theorigin (for example, the soil), through exposure (for example, dirt on
the hands), and assimilation (for example, gastric absorption), to theimpact on a specific organ or physiological mechanism (for example,
the enzymatic system); and (ii) the hypothetical association must be
predictive. If this association is positive in one geofgraphical area, it
must also be positive in a geologically similararea.
2 Back in the sixteenth century, Paracelsus defined a basic law of
toxicology: any increase in the amount or concentration of elements
causes an increase in negative biological effects, which can lead tothe inhibition of certain biological functions and, ultimately, to death.

BOOK OF ABSTRACTS | 12th European Congress of Integrative Medicine · 1st International Symposium on Integrative Health and Education

These harmful biological effects can result from either a deficit or an
excess in concentration. Trace elementsoroligoelementsformaspecialcase.InGeochemistry,thetermtraceelementisused for elements occurring at concentrations lower than 0.1%. An oligoelement (or micronutrient), would have the same definition, but it is also an essentialtrace element forlife.
A naturally high or low concentration of an element, especially one
present in trace amounts,isaresultofnaturalprocessesthatleadtoitsaccumulationordispersionatparticular sites of the Earth’s crust. The factor that determines the possibility of this happening depends on thegeological peculiarity and not so much on the size of a particulararea.
Sincetimeimmemorialithasbeensaidthatwearewhatweeatand,inMedicalGeology, we are not only what we eat, but also what we drink,breathe or absorb through the skin. Without dismissing anthropic activities, the composition of air, water and food is directly influenced
by interactions with the geological environment, which is manifested
primarily through soil, air and water. When rain falls on the earth’s
surface, on the rock and the ground, itisafluidwithaverylowsalinityandanacidicpHofaround5.Itrepresentsanaggressivewater fortherock.
Plantrootsandplantlitter(ifpresent)alsoprovideacidityandincreasethewater’s ability to alter and dissolve the rock. As this water flows
through the ground, there is sufficient time for it to be mineralised tothe point of saturation in the different ions. This is contrast to what happens with water that forms surface-runoff, which has a shorter timein contact with the mineral phases and so a shorter time to dissolve
substances. Generally, in the absence of pollution surface-runoff has alower mineralization thangroundwater.
The chemical composition of groundwater is a reflection of its flowpath and of its history through the rocks it makes contact with; of themineral phases it has interacted with and the reactionsthathaveaffectedit,andsoon.Thephysico-chemicalprocessesthattakeplaceinthe water-rock interaction, and even in the mixing of two waters of different
compositions, correspond to the ceaseless transitions to achieve newionicequilibria.
Therefore, water consumed by animals and humans in a particulararea is a means through which they contact and interact with theirgeological environment. Some of the elements naturally found in water can be especially harmful to health, even in trace concentrations.
These are the so-called Potentially Toxic Geogenic Trace Elements(PTGTEs), which may be present at levels that represent a risk to health. An example is arsenic and groundwater enriched in this element.
Chronic exposure to high concentrations of these elements throughdrinking water is one of the best-studied topics in the field of Medical
Geology.
An example of these PTGTEs is shown by the recent studies carriedout on HydrogeoToxicity (HGT) in Spain. HGT is a term that was first
defined as an index that assesses, intermsofhealthrisk,theconcentrationofcertainPTGTEsingroundwater.Assuch,itisdefined asthequotientbetweentheconcentrationofaparticularPTGTEinawatersampleanditsupper limit value in drinking water as defined by the World
Health Organisation (WHO),i.e.:
HGTPTGTE= [PTGTE water]/[ PTGTE WHO]
It is understood that values of HGTPTGTE> 1 indicate that the concentration exceeds the admissible limit for drinking water. Furthermore,
not only must the HGT of a single element be taken into account, butalso the possibility of a combined or multiple HGT, which is the sumof the individual HGTPTGTEs (Giménez Forcada 2017a,b). Within Earth
Sciences, HGT studies are intended to be predictive; this is possible
because groundwater is a dynamic medium whose natural chemicalcomposition reveals important features about its geological environ-61

ment, on a regional scale (Giménez-Forcada, 2018).
3 Building a bridge between Earth Sciences and Health Sciences is
not easy. The topic is certainly of great interest, but there are obstaclesin the paths initiated from either scientific field (geology and health)
to meeting and collaborating. However, the demands of the new millennium invite us to face the challenge of interdisciplinary collaboration in order to achieve integrated knowledge and understanding.
Rapid growth is envisaged in this new scientific field of Medical
Geology, an emerging or re-emerging discipline that offers us the possibility of integrating geological understanding into health and publichealth policies.
REFERENCES
Centeno, J.A., Giménez-Forcada, E., Pena-Búa, P. (2016). La Geología Médica: una disciplina emergente.
Rev. salud ambient. 16(2):164-168
Davies,B.E.,Bowman,C.,Davies,T.C.,Selinus,O.(2005).MedicalGeology:PerspectivesandProspects.In OlleSelinus(Ed).EssentialsofMedicalGeology.Impactsofthe NaturalEnvironmentonPublicHealth. Chapter 1. 1st Edition. Elsevier. Academic Press. 832 pp.Giménez2019
Giménez-Forcada, E. (2018). Introducción a la Geología Médica. Ed. Catarata. 112 pp.
Giménez-Forcada, E., Timón-Sánchez, S., & Kohfahl, C. (2017b). Hydrogeotoxicity from arsenic and uranium in the southern Duero Basin, Spain. Journalof Geochemical Exploration, 183, 197-205.
Giménez-Forcada. E.; Vega-Alegre, M.; Timón-Sánchez, S. (2017A). Characterization of regional cold- hydrothermal inflows enriched in arsenic and associated trace-elements in the southern part of the Duero basin (Spain), by multivariate statistical analysis. Science of the Total Environment 593: 211- 226.
Giménez-Forcada, E. y Ordóñez-Delgado, S. (2019). Geología Médica: ¿Un
nuevo espacio científico?.
Enseñanza de las Ciencias de la Tierra (en prensa).
Låg, J. & Bølviken, B. 1974: Some naturally heavy-metal poisoned areas ofinterest in prospecting, soil chemistry, and geomedicine. Norges geol. Unders.
304, 73-96.
Läg, J. (1990). Geomedicine. Boca Raton, USA: CRC Press. 278 p.
Mulder, E. de (2008) International Year of Planet Earth. J. Environ. Monit.,
10, 164-165.
Selinus, O. (Ed). Essentials of Medical Geology. Impacts of the Natural Environment on Public Health.
Chapter 15. 1st Edition. Elsevier. Academic Press. 832 p.

4 ART IN THE HOSPITAL OF THE FUTURE
Stefan N. Willich, Charité University Medicine
Berlin, Germany
Ph.D. in biochemistry and human physiology,
board certified in clinical chemistry and toxicology. University Missouri (Kansas City/USA)
There is increasing evidence of important associations between arts and medicine. Architecture and the environment of
hospitals has been shown to be important for the well-being ofpatients and staff and may even have impact on health outcomeof patients. Therefore, the design of hospitals should activelyincludetakingintoconsiderationhealthrelatedaspects. Onaclinicalcarelevel,artstherapies have long been practiced beginning alre-

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BOOK OF ABSTRACTS | 12th European Congress of Integrative Medicine · 1st International Symposium on Integrative Health and Education

ady in medieval times and continuing through modern medicine,
however, scientific evidence is still sparse overall. For patientswith some psychiatric, neurologic, cardiologic disorders, exposure to arts including music, visual arts, dance has been shown
toimprovemedicaloutcomes.Inothermedicalfieldsincludingneonatology,anaesthesiology,surgery arts therapy may have supporting effectiveness, available studiy results encourage to pursue
further research projects. The potential mechanisms of action ofarts therapy are by and large stillunclear.
Theincreasingclinicalexperienceandscientificevidencethatartscansupporthealingonseverallevels have potential implications
for future hospitals. The buildings may include artistic elements
such as paintings, sculptures, installations, even live performances. Therapeutic strategies should systematically explore potential effectiveness of elements of arts therapy and may eventually lead to consideration in guidelines. Cost benefit assessment
is also needed to determine whether and which arts therapies
should be reimbursed by healthinsurance.

INTEGRATIVE MEDICINE APPROACHESTO TREATMENT IN PSYCHIATRYRAB PSYCHIATRIC HOSPITAL,
UNIVERSITY OF RIJEKA, FACULTY OF
MEDICINE CROATIA
Vesna Šendula Jengić
Abstract
The mission of Rab Psychiatric Hospital is to provide for eachpatient on a personalized level in order to achieve the best treatment results. Therefore, each person must be regarded in a holistic manner and offered a range of adequate treatments which
complement the traditional biological and psychotherapeutic
treatment approaches. Last two decades Rab Psychiatric Hospital has been introducing innovative therapeutic approaches fortreatment persons with various mental disorders, addictions,cPTSD , and different neurocognitive deficits. Today the hospital is well known for its application of the outdoors as a versatile therapeutic tool, predominantly with the lavender field andtherapeutic gardens which serve for various purposes, such ashorticulture, neurocognitive therapy, mindfulness, aromatherapy, various psychotherapeutic techniques, etc. Music therapy,
physiotherapy, biofeedback and neurofeedback are also appliedfor various conditions and last but not least - the therapeutic dog
Aron is the star of the multidisciplinary therapeutic team.
Efforts to optimize psychotherapeutic techniques, pharmacotherapy and recovery principles with the aim of reinforcing
patient autonomy and therapeutic partnership, show relatively
optimistic results even with severely mentally ill patients in terms of decreased number of involuntary hospitalizations, closed
wards, etc.
Can we promote emotional health and body-mind wellness,
avoid stigmatization through proper positioning in the overall
healthcare practice from prevention to rehabilitation is an ethicalbut also very professional and humane question.
key words: integrative medicine, Rab Psychiatric Hospital, psychiatry

MEDICINAL MUSHROOMS AND
INMUNE SYSTEM
Pellicer-Sabadí, Cristina PhD
Director of Medicus Gaia Centre Mèdic, Barcelona(Catalonia)
Medicinal mushrooms are those fungi which produce medicallysignificant metabolites or can be induced to produce such metabolites using biotechnology. The range of medically active compounds
that have been identified include antibiotics, anti-cancer drugs, cholesterol inhibitors, psychotropic drugs, immunosupressants and evenfungicides.Itcanbeusedtodiscoverortoproducesynthethicmetaboliteslikepaclitaxel from Penicillium raistrickii, other mitotic inhibitors like
vinblastine, vincristine or can be used the beta-glucan fungal extracts
lentinian, polysaccharide-k and polysaccharide peptide as immunologic adjuvants. Nowadays they have been intensively studied in order to reveal the chemical nature and mechanisms of action of theirbiomedical capacity and compounds of fungal origin provide a vast
reservoir of potential innovational drugs. Medicinal mushrooms thathave an antiinflammatory and immune- enhancing,immune-modulation
effectinclude maitake (Grifola frondosa),
shiitake (Lentinus edodes), reishi (Ganoderma lucidum), and turkey tail (Trametes or Coriolus versicolor), Lion’s Mane (Hericium erinaceus), Cordyceps sinensis, Agaricus blazeiMurrill.
We review the effect of these mushrooms in several immune diseases: ulcerative colitis, autoimmune thyroid diseases, Crohn’s disease,rheumatoid arthritis, type 1 diabetes mellitus, systemic lupus erythematosus and asthma as immunomodulator treatment as quality oflife and symptoms treatment.
Key words: ulcerative colitis, Crohn’s disease, rheumatoid arthritis,
type 1 diabetes mellitus, systemic lupus erythematosus, immune disease, autoimmune disease, autoimmune thyroid diseases, Graves’s
disease, Hashimoto’s thyroiditis, medicinal mushrooms, maitake, Grifola frondosa, shiitake, Lentinula edodes, reishi, Ganoderma lucidum,
turkey tail, Trametes versicolor, Coriolus versicolor, Lion’s Mane, Hericium erinaceus, Agaricus blazei Murrill, Cordyceps sinensis.
Referencias:
He T, Zhao R, Lu Y, Li W Hou X, Sun Y, et al. Dual- Directional Immunomodulatory Effects of Corbrin Capsule on Autoimmune ThyroidDis eases. Evid Based Complement Alternat Med. 2016;2016:1360386.
Epub 2016 Sep18.
Chen JL, Chen YC, Yang SH, Ko YF, Chen SY. Immunological alterations inlupus- prone autoimmune (NZB/NZW) F1 mice by mycelia Chinesemedicinal fungus Cordyce ps sinensis-induced redistributions of peripheral mononuclear Tlymphocytes. Clin Exp Med. 2009Dec;9(4):277-84.
Kumaran
S,Palani
P,Nishanthi R, Kaviyarasan V.Studies on screening, isolation and purification of a fibrinolytic protease from an isolate(VK12)ofGanodermalucidumandevaluationofitsantithromboticactivity.Med
Mycol J.2011;52(2):153-62.
Cai Z, Wong CK, Dong J, Jiao D, Chu M, Leung PC, et al. Anti- inflammatory activities of Ganodermalucidum(Lingzhi)
and SanMiao- San supplements in MRL/lpr mice for the treatment of systemic lupus erythematosus. Chin Med. 2016 Apr29;11:23.
Kwok Y, Ng KF, Li CC, Lam CC, Man RY. A prospective, randomized, double- blind, placebo-controlled studyof

BOOK OF ABSTRACTS | 12th European Congress of Integrative Medicine · 1st International Symposium on Integrative Health and Education63

the platelet and globalhemostatic effects of Ganoderma lucidum (LingZhi) in healthy volunteers. Anesth Analg. 2005 Aug;101(2):423-6
Wang
MF,Zhu
QH,He
YG. Treatment with Cordyceps sinensis enriches Treg population in peripheral lymph nodes and delays typeI diabetes development in NOD mice. Pharmazie. 2013 Sep;68(9):768- 71.
Yurkiv
B, Wasser SP,Nevo E, Sybirna NO. The Effect ofAgaricus brasiliensis and Ganoderma lucidum Medicinal Mushroom
Adm inistrationon the L-arginine/Nitric Oxide System and Rat Leukocyte Apoptosis in Experimental Type 1 Diabetes Mellitus. Int J Med Mushrooms.2015;17(4):339-50.
Tie L,Yang HQ,An Y,Liu SQ,Han J,Xu Y, et al. Ganoderma lucidum polysaccharide accelerates refractory wound healing by inhibition of mitochondrial oxidative stress in type 1diabetes.
Cell Physiol Biochem. 2012;29(3-4):583-94.
Preuss HG,Echard B,Fu J,Perricone NV,Bagchi D,Kaylor M,Zhuang C. Fraction SX of maitake mushroom favorably influences blood glucose levels
and blood pressurein streptozotocin-induced diabetic rats. J Med Food.
2012Oct;15(10):901-8.
Shi B,Wang Z, Jin H,Chen YW,Wang Q,Qian
Y. Immunoregulatory
Cordyceps sinensis increases regulatory T cells to Th17 cell ratio an d delaysdiabetes in NOD mice. Int Immunopharmacol. 2009May;9(5):582-6.
Zhou S,Liu Y,Yang Y,Tang Q,Zhang J.
Hypoglycemic Activity of Polysaccharide from Fruiting Bodies of
the Shaggy Ink Cap MedicinalMushroom, Coprinus comatus (Higher Basidiomycetes), on Mice Induced by Alloxan and Its Potential Mechanism.
Int J Med Mushrooms.2015;17(10):957-64.
Zhou S,Liu Y,Yang Y,Tang Q,Zhang J.
Hypoglycemic Activity of Polysaccharide from Fruiting Bodies of
the Shaggy Ink Cap MedicinalMushroom, Coprinus comatus (Higher Basidiomycetes), on Mice Induced by Alloxan and Its Potential Mechanism.
Int J Med Mushrooms.2015;17(10):957-64.
Therkelsen SP,Hetland G,Lyberg T, Lygren I,Johnson E.
Effect of the Medicinal Agaricus blazei Murill-Based Mushroom Extract,AndoSanTM,
on Symptoms, Fatigue and Quality of Life in Patients with Crohn’s Disease ina Randomized Single-Blinded Placebo Controlled Study. PLoS One. 2016
Jul 14;11(7):e0159288.
Qin M,Geng Y,Lu Z,Xu H, Shi JS,Xu X,Xu ZH.Anti- Inflammatory Effectsof Ethanol Extract of Lion’s Mane Medicinal Mushroom, Hericiu merinaceus(Agaricomycetes), in Mice with Ulcerative Colitis. Int Med Mushrooms.2016;18(3):227-34.
Hetland G, Johnson E, Lyberg T, Kvalheim G. The
Mushroom Agaricus blazeiMurill Elicits Medicinal Effects on Tumor, Infection,
Allergy, andInflammationthrough Its Modulation of Innate Immunity andAmelioration of Th1/Th2 Imbalanceand Inflammation. Adv Pharmacol
Sci.2011;2011:157015.
P. Therkelsen, G. Hetland, T. Lyberg, I. Lygren & E. Johnson. Cytokine
Levels After ConsumptionofaMedicinalAgaricusblazeiMurill-BasedMushroomExtract,AndoSan TM, in Patients with Crohn’s Disease and Ulcerative
Colitis in a Randomized Single- Blinded Placebo-Controlled StudyScandinavian Journal of Immunology, 2016, 84, 323– 331
Wang
D,Zhang Y,Yang
S, Zhao
D,Wang M.
Apolysaccharide from cultured mycelium of Hericium erinaceus relie-colonic epithelial cell
Food Nutr Res. 2019 Feb12;63.
Shao S,Wang
D, Zheng W,Li X,Zhang H, Zhao D,Wang
M. A unique polysaccharide from Hericium erinaceus mycelium ameliorates acetic acid- inducedulcerative colitis rats by modulating thecomposition of
the gut microbiota, short chain fattyacids levels andGPR41/43 respectors. Int Immunopharmacol. 2019Jun;71:411-422.
Lim BO.
Coriolus versicolor suppresses inflammatory bowel disease by Inhibiting the expression of STAT1 and STAT6 associated with IFN-γ and
IL-4 expression. Phytother Res. 2011 Aug;25(8):1257-61.
Hasnat MA, Pervin M, Cha KM, Kim SK, Lim BO. Antiinflammatory activity on mice of extract of Ganoderma
lucidum grown on rice viamodulation of MAPK and NF-κB pathways. Phytochemistry. 2015 Jun;114:125-36.
Førland DT, Johnson E, Saetre L, Lyberg T, Lygren I, Hetland G.
Effect of an extract basedon
the medicinal mushroom Agaricus blazei Murill on expression ofcytokines and calprote
ctin in patients with ulcerative colitis and Crohn’s disease.
Scand J Immunol. 2011 Jan;73(1):66-75. doi: 10.1111/j.13653083.2010.02477.x.
Mitamura T, Sakamoto S, Suzuki S, Yoshimura S, Maemura M,
Kudo H. Effects of lentinan on colorectal carcinogenesis in mice withulcerative colitis. Oncol Rep. 2000May-Jun;7(3):599-601.
Therkelsen SP, Hetland G, Lyberg T, Lygren I, Johnson E.
Effect of a Medicinal Agaricus blazei Murill-BasedMushroomExtract,
AndoSan™, on Symptoms, Fatigue and Quality of Life in Patients with
Ulcerative Colitisina Randomized Single-BlindedPlacebo Controlled Study. PLoS One.
2016 Mar 2;11(3):e0150191.
Hanaoka R, Ueno Y, Tanaka S, Nagai K, Onitake T, Yoshioka K,
Chayama K. Thewatersoluble extract from cultured medium of Ganoderma lucidum (Reishi) mycelia(Designat ed as MAK) ameliorates murine colitis inducedby trinitrobenzene sulphonic acid.
Scand J Immunol. 2011 Nov;74(5):454-62.
Shi L, Lin Q, Yang T, Nie Y, Li X, Liu B, et al. Oral administration of
Lentinus edodes β-glucans ameliorates DSS-induced ulcerative colitis in mice via MAPK-Elk- 1 and MAPK-PPARγ pathways. Food Funct.
2016 Nov 9;7(11):4614-4627.
Takimoto H,Kato
H,Kaneko M,Kumazawa
Y. Amelioration of skewed Th1/Th2 balance in tumor-bearing andasthmainduced mice by oraladministration of Agaricus blazei extracts. Immunopharmacol Immunotoxicol. 2008;30(4):747-60.
SerranoHernándezA.Helper(TH1,TH2,TH17)andregulatorycells(Treg,TH3,NKT) in rheumatoid arthritis. Reumatol Clin. 2009 Apr;5 Suppl1:1-5.
E.-M. Noh1, J.-S. Kim1, H. Hur, B.-H. Park, E.-K. Song2, M.-K. Han, etal. Cordycepin inhibits IL-1b-induced MMP-1 and MMP-3 expression
in rheumatoid arthritis synovial fibroblasts. Rheumatology
2009;48:45–48
Lam FF, Ko IW, Ng ES, Tam LS, Leung PC, Li EK. Analgesic andves ulcerative coli tis by counteracting oxidative stress and improving
mitochondrial function. Int J Biol Macromol. 2019 Mar15;125:572579.
Xie J, Liu Y, Chen B, Zhang G, Ou S, Luo J, Peng X.
Ganoderma lucidum polysaccharide improves rat DSS
induced colitis by altering cecalmicrobiota and gene expression ofanti- arthritic effects of Lingzhi and San Miao San supplementationina rat modelof arthritis induced by Freund’s complete adjuvant. J
Ethnopharmacol. 2008 Oct 30;120(1):44-50.
Yi Xi Bao, Chun Kwok Wong, Edmund Kwok Ming Li, Lai
Shan Tam,3 Ping Chung Leung,1 Yi Bing Yin, et al. I01Lm58IP39m2Iu-23n59o17p3harmacology and Immunotoxicology, Vol. 28,

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No. 2, June 2006: pp. 1–9 Immunomodulatory Effects of Lingzhi and
San-Miao-San Supplementation on Patients with Rheumatoid Arthritis. Immunopharmacology and Immunotoxicology, 28:197–200, 2006
Li EK, Tam LS, Wong CK, Li WC, Lam CW, Wachtel-Galor S, etal. Safety and efficacy of Ganoderma lucidum(lingzhi)
and San Miao San supplementation in patients withrheumatoidarthritis:
adoubleblind, randomized, placebo-controlledpilottrial.
ArthritisRheum. 2007 Oct 15;57(7):1143-50.
TranPT,DatNT,DangNH,VanCuongP,LeeS,HwangboC,etal. Ganomycin I from Ganoderma lucidum attenuatesRANKL
mediated osteoclastogenesis by inhibiting MAPKsand NFATc1.
Phytomedicine. 2019 Mar1;55:1-8.
Ho YW, Yeung JS, Chiu PK, Tang WM, Lin ZB, Man RY, Lau CS.
Ganoderma lucidum polysaccharide peptide reduced the productionof proinflammatory cytokines in activated rheumatoid synovial fibroblast. Mol Cell Biochem. 2007 Jul;301(1-2):173-9.
Zhu X,Okubo
A, Igari N,Ninomiya K,Egashira Y. Modified
rice bran hemicellulose inhibits vascular endothelial growth factor- inducedangiogenesis in vitro viaVEGFR2 and its downstream signalingpathways. Biosci Microbiota Food Health.2017;36(2):45-53.

HORMESIS: INTERVENTIONALSTRATEGIES TO RESTORE STRESS AXES
Daniel de la Serna.
Instituto Español de Psiconeuroinmunología clínica.
Key words: Hormesis, chronic inflammation, cooperation, desynchronyzation, intermittent challenges.
Abstract
Establishing the links between the central nervous system and theimmune system have been crucial for understanding the adaptabilityof Homo sapiens to threatening environments through evolution. The
psycho-neuro-endocrine pathways connecting the brain and the immune system have been an evolutionary key regulatory mechanism
for an optimal response in order to survive or reproduce through thedevelopment of complex immune responses or behaviors.
Today, chronic inflammation is related with antropogenic factors
including chronic psicosocial stress and suposses a main risk factor for
current chronic non-communicable diseases (CNCD) [1]. The pleiotropic effect of certain mechanisms of action could be responsible forchronic inflammatory manifestations, due to the aberrant expressionof programs that were preserved to cope with acute events [2]. Those same programs that in the past helped our ancestrors to survive,
nowadays are responsible to induce desynchronization between thesympathetic nervous system and the hypothalamic pituitary adrenal
axis.
Cooperation and synchronization between stress axes are important events to mantain the metabolic homeostasis through energetic distribution in the body and for ending correcly the acute inflammatory response, becoming both of them, basic mechanisms toprotect the body against chronic inflammation [3]. As said before,chroinc stress is a major risk factor for inflammation and for uncoupling these two axes, lowering the tresshold for any other factor triggering for the initiation of the disease [4].
Desynchronization, takes place on different forms and at different

levels during chronic inflammation [5]. For example aging is a wellknwon factor inducing a slow desynchronization process [6] wich ends
with altered plasma noradrenaline in relation to other steroid hormones including cortisol [7]. Another way of presenting desynchronization may be due to disruptions on the circadian rythm [8], including
the immune cell itself as it happens during the presymptomatic phaseof disease leading to an increased reactivity of the immune system.
Coupling back these two axes is a necessity in order to dampen peripheral inflammation due to the cooperation between cortisol andnoradrenaline, which has been recently demonstrated in patientswith reumathoid arthritis [9].
Somerecentresearchindicatehowgettingbackincontactwitholdandwellknownacutestress factors analogues with those suffered by ourancestors, could ease the metabolic and inmmunological restoration
through hormetic effects[10].
The term Hormesis, just as Calabrese and Mattson have recently
stated, “should be viewed in the light of evolutionary-based adaptive responses, also as a measure of performance and resilience of any
living system including for example: cell proliferation, disease resistance, aging/longevity and others that are fundamental for survival andthriving in challenging environments” [11].
Hormesis is characterized by the simultaneous stimulation of many
independent celular functions, each one, with its own set of quantitatively hormetic features (DNA repair, antioxidant defenses and others)
whose actions are regulated by multiple pathways producing a metabolically integrated celular response [11].
Various studies [12,13], have shown how the use of intermittent
challenges with hormetic effects improve subjective and objective
wellbeing of individuals with CNCD, whyle having favourable effects
on immunological, metabolic and behavioural indices. Intermittent
cold, heat, fasting and hipoxia together with phytochemicals in multiple food products, have widespread influence on many pathways
related with overall health.
References.
Egger G. In search of a Germ Theory Equivalent for Chronic Disease. Prev.
Chronic Dis 2012; 9:110301. DOI:10.5888
Pruimboom L. Physical inactivity is a disease synonymous for a non-permissive brain disorder. Medical Hypotheses 77, 708-713(2011)
Straub RH et al. Energy regulation and neuroendocrine-immune control inchronic inflammatory diseases. J Intern Med 2010;267:543-60
Rainer H. Straub. The Origin of Chronic Inflammatory Systemic Diseases
and their Sequelae. Academic Press, Elsevier 2015. Chapter VII, pg243
Cervantes OC, Wu M, Ehlen JC et al. Dysregulation of inflammatory
Responses by Chronic Circadian Disruption. The Journal of Immunology
2010;185:5796-5805
Brown, S. A., Pagani, L., Cajochen, C. et al. Systemic and cellular reflections on ageing and the circadian oscillator: a mini-review. Gerontology 57,
427–434(2011).
JaraLJ.Neuroinmmunoendocrineinteractioninautoinmunerheumaticdiseases:anew challenge for the rheumatologist. Reumatol. Clin.2011;7(2):8587
Rainer H. Straub. The Origin of Chronic Inflammatory Systemic Diseases
and their Sequelae. Academic Press, Elsevier 2015. Chapter VII, pg254.
Straub RH, Günzler C, Luitpold E, et al. Anti-inflammatory cooperativityof corticosteroids and norepinephrine in rheumatoid arthritis sinovial tissue
in vivo and in vitro. The FASEB Journal, 16(9), 993-1000. Doi:10.1096/fj.020085com
PruimboomL,Ruiz-NúñezB,RaisonCh.etal.Influenceofa10-DayMimicofOurAncient Lifestyle on Antropometrics and Parameters of Metabolism andBOOK OF ABSTRACTS | 12th European Congress of Integrative Medicine · 1st International Symposium on Integrative Health and Education

Inflammation: The “Study of Origin”. BioMed Research International. Volume
2016, Article ID 6935123, 9 pages
Calabrese EJ, Mattson MP. How does hormesis impact biology, toxicology,
and medicine?. Nature Parter Journals. Aging and Mechanisms of Disease(2017)3:13; doi:10.1038/s41514-017-0013-z
Mattson MP. Challenging oneself intermittently to improve health. Dose-Response, 12:600-618,2014.
Pruimboom L, Muskiet F. Intermittent living; the use of ancient challenges
as a vaccine against the deleterious effects of modern life – A hypothesis.Medical Hypothesis 120 (2018)28-42

UNRESOLVED INFLAMMATION.
BACKGROUND OF THE CHRONIC AND
DEGENERATIVE PATHOLOGY
Arturo O’Byrne MD. Colombia
Profesor de cátedra en Medicina Integrativa. Universidad Javeriana. Colombia.
Whenimpactpublicationstalktousaboutphysiologicalinflammationasafundamental mechanism to purify the cellular microenvironment andto aid structural and function recoveryoftissues(Nature2002),theyopenupnewfrontiersconcerninganUNKNOWN topic likeresoleomics.
The post-genomic era has led us to the knowledge of regulatory
networks, one of the most important being inflammation resolution.
When Charles Serhan and his group at Harvard called attention to theendogenous mechanisms in inflammation resolution (Rheum Dis Clin N
Am 2004) and how these fail due to lifestyle actors such as diet, sedentary lifestyles, stress and a wide range of causes that block the capacity
for inflammationresolution,anentireuniverseofexplanationsconcerningchronicitybegan to beunderstood.
Thisknowledgeconcerningthesuppressivetherapeuticformofinflammationhashada decisive impact. Anti-inflammation is NOT the sameas Pro-resolution, and we have to change the tendency to suppress all
inflammatory processes as if inflammation were bad, ignoring the evolutionary mechanisms which created inflammation as the most important biological response mechanism to aggression and/ortrauma.
The integrative view of patients with chronic inflammation leads us
to pay essential attention to the “personal” factors which block resoleomics.
Anti-inflammatorytherapymustberestrictedonlytosituationswhichputthestructural integrity of tissues or the patient’s life indanger.
Understanding the changes from the diet, orthomolecular replacement, bioregulation using multi-modal and multi-objective drugs at low
concentrations, photobiostimulation, and a wide-ranging coadjuvant
therapeutic arsenal, will prevent iatrogenesis generated by the collateral effects of suppressive drugs.

PSYCHONEUROINMUNOLOGY AND
GLOBAL HEALTH
Neuroinflammation: anxiety, stress and chronic pain.
Xevi Verdaguer, Master director Pnie (Barcelona/Madrid) Graduate in Physiotherapy. Researcher and scientist disseminator. xeviverdaguer.com

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Psychoneuroimmunologyisthestudyoftheinteractionsamongbehavioral,neuralandendocrine,andimmuneprocesses.Thebraincommunicateswiththeimmune system through autonomic
nervous system and neuroendocrine activity. Both pathwaysgeneratesignalsthatareperceivedbytheimmunesystemviareceptors
on the surface of lymphocytes and other immune cells. The direction and/or magnitude of the effects of behavioral factors inmodulating immune responses, however, depend upon the nature of the behavioral circumstances, the nature of the antigenic
stimulation, and the temporal relationship between them; theimmune response and when it is measured; a variety of host factors; and the interactions among these variables. We will provide examples of these relationships and how this approach could
help us to better health outcomes in ourpatients
Aim
Psychosocial stressors are a well-documented risk factor formental illness. Neuroinflammation, in particular elevated microglial activity and Mast cell- Microglia crosstalk has been proposed
to mediate this association. A number of preclinical studies haveinvestigated the effect of stress on microglial activity. However,these have not been systematically reviewed before. We consider this implications for the role of stress in the development of
mental and chronic pain disorders.
Conclusion
Thereisconsistentevidencethatarangeofpsychosocialstressorsleadtoelevated microglial activity in the hippocampus and goodevidence that this is also the case in other brain regions. These
effects were seen with early-life/prenatal stress, as well as stressors in adulthood. We consider these findings which proposesthat early-lifestressprimesmicroglia,leadingtoapotentiatedresponsetosubsequent stress.
Theimplications forunderstandingthepathoaetiologyofmentalandchronicpain disorders and new treatments will beconsidered.
Bibliografia:
ReemAbdel-Haq,Johannes
C.M.Schlachetzki,Christopher
K. Glass,Sarkis
K. Mazmanian. Microbiome–microglia connections via the gut–brain axis. Journal of Experimental Medicine Jan 2019, 216 (1) 41-59;
DOI: 10.1084/jem.20180794
FrickLR,WilliamsK,PittengerC.Microglialdysregulationinpsychiatricdisease.Clin Dev Immunol.2013;2013:608654.

CONTRIBUTION OF POSTUROLOGYIN THE TREATMENT OF CHRONICRACHIALGIAS
Villeneuve Pha, M ulliez Ta, Martinez Carrasco
Mab, Parreira RBac, Viseux Fade.
a Posture Lab. Paris Franceb Villeneuve Escuela de Posturología. Barcelona
EspanaC School of Manual and Postural Therapy, Londrina Brazil
dLaboratoired’automatique,demécaniqueetd’informatiqueindustriellesethumaines(LAMIH),

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BOOK OF ABSTRACTS | 12th European Congress of Integrative Medicine · 1st International Symposium on Integrative Health and Education

UMR CNRS 8201, université de Valenciennes et duHainaut-Cambrésis (UVHC), 59313 Valenciennes,France
e Centre d’évaluation et de traitement de la douleur (CETD), centre hospitalier de Valenciennes(CHV), 59322 Valenciennes, France
Chronic low back pain (CLBP) represents one of the major causes ofglobal disability. CLBP is a very common pathology, being the first cause of work-associated accidents of musculoskeletal origin in France,with 5–10% of CLBP patients being responsible for 70–80% of healthexpenses.
A precise and exhaustive etiological diagnosis of chronic low backpain is difficult to make, as few validated tests are available. The difficulty of the clinical evaluation could explain the lack of effectivenessin the therapeutic management of chronic low back pain. Discogenic
origin is generally assumed to be the main cause of non-specific low
back pain.
Clinical evaluation and posturology
Several authors suggest that abnormal lumbar kinematic couplings
may be an indicator of non-specific CLBP. The PosturoDynamic Test
(PDT) is an original clinical test that has been used for 20 years in posturology to evaluate coupled motions in humans standing, during lateral movement of the spine. Through the evaluation of the tonic activity of the para-vertebrae muscles, spinal kinematic behaviors analysis
offers a systemic complementary assessment in the management of
CLBP. PDT is based on the hypothesis that physiological kinematics ofthe lateroflexion (LF) movement of the spine is coupled to rotationalmotions in the transverse plane. Previous Biomechanical research has
established some evidence in this direction.
We evaluate: (i) the inter-rater reliability and (ii) the validity of the
PDT compared with kinematic evaluation using motion capture system, considered in this study as the “gold” standard.
The weighted values for inter-rater (left LF) were > 0.64 for expert
and <0.3 for novice. For the comparison between human and machine kappa, values for inter-rater were > 0,61 for expert and <-0,19 novice for the comparison between human and machine kappa
These results objective the validity of PDT. They confirm its inter-rater and show the importance of the clinical experience. PDT is a quick
reliable and non-instrumental test, which can be used as first for abetter characterization and clinical interpretation of spine kinematics
of standing subject.
The PDT show three kind of cinematic behaviors, one, where LF androtation were in the opposite direction, is not found in any healthy
subjects. The two others behaviors are find in CLBP patients : the LF
drive no rotation or rotation in the same direction. We hypothesisthat the second behavior is in relation with the intervertebral disc (Villeneuve Ph, Villeneuve-Parpay S. 2017, Viseux and al. submit).
CLBP is often related to neurogenic dysfunction
It may be a result of a tunnel syndrome, a neural stretch or a central hyperexcitability (Sanzarello et al 2016). These possibilities may be
associated with a chemical or mechanical disorder which may cause
an inflammatory stimulation of the nervi nervorum – polymodal C-fiber – which can generate local pain or pain at the neural pathway.
Besides, the neuronal conduction and integration of the dysfunctional
region will be interrupted resulting in postural adaptations.

Manual neurostimulations and postural insoles two complementary treatments
The soul of posturolgy treatment is based on the mechanoreceptor
stimulations to alter postural control. On one hand, we develop a new
manual therapeutic approach called “Neurosensorial Posturotherapy(PNS)” (Villeneuve 2012a) which used manual neurostimulations. On
the other hand, the postural insoles used in France since 1980.
Neurosensorial Posturotherapy (PNS)PNS is based on the well-known manual techniques from the eighteenth century (Barber 1998), as well as the neurophysiological basesof postural regulation, which prove to be a valuable adjunct in thecontext of chronic pain. The treatments used in PNS consist of manual neurostimulation directly on the nerve that modulate the muscle
hypertonicity and nociception in a simple and long lasting (Villeneuve
2012b) way. The effects of the NPT technique is effective in patientswith chronic LBP by promoting reduction of pain symptoms, improving mobility, flexibility, as well as promotes improvement in functional capacity, stability body, heart rate variability and chronotropic
response (Villeneuve and al 2017). Manual neurostimulation can beapplied to discogenic dysfunctions (Villeneuve 2017).
Viseux and al (submit), in a review recall that the intervertebral discis innervated, and pain potentials are present in the outer part of theannulus fibrosus. Several studies have demonstrated nerve endings in
the annulus fibrosus. In adults, five types of nerve terminations canbe found. The source of the nerve endings in the lumbar discs is thelumbar sinuvertebral nerves and branches of the lumbar ventral rami
and the grey rami communicants. The lumbar intervertebral discs arealso innervated by branches of the sympathetic nervous system.
This could bring the following assumptions:
Neurogenic lumbar disc pain could be characterized by(i)hypertonicity bilateral muscle, multisegmental,(ii)bilateral inverted of behavior kinematics of the lumbar spine.
Neurogenic lumbar zygapophysial joint pain could be characterizedby(i)unilateral muscle hypertonia, mono segmental,(ii)inversion homolateral to neural dysfunction of the kinematic behavior of the spine lumbar.
Postural insole
During early last century, the first French podiatrists took their patients’ entire morphology into account and their treatments made theconnection between foot deformity and vertebral pain.
In 1980, French doctor René Bourdiol, understood that wedges placed under the plantar sole not only had a mechanical action, but alsoa stimulatory effect on the nervous system At the same time, Okubo
and Baron (1980) obtained significant reduction of the postural sway
area after plantar stimulations (one mm high). They introduced a paradigm shift. In anglo-saxon countries the model biomechanic developped by Root and al (1971) was the reference, but now this modelis largely controversial. Jarvis and al (2017) recommend that cliniciansstop using the Root model. In European countries it is being replacedby neurosensorial model developped by Bourdiol (1980), Villeneuve-Gagey (1990).
In 1990, based on clinical and fundamental research findings, Villeneuve and Gagey put forward that plantar stimulations induced
predictable and orientated postural reactions. This was confirmed byvibrotactile stimulations (Kavonuoudias 1998), electrical stimulations

BOOK OF ABSTRACTS | 12th European Congress of Integrative Medicine · 1st International Symposium on Integrative Health and Education(Nakajima 2006) and plantar stimulations of 3-mm hight, (Janin 2004
; 2009). In 2000, Leporck showed that the balance was significantly
modified when a full sheet of paper was placed under the right foot.
Then Priplata and al (2003) confirmed that subliminal plantar stimulations at the threshold of conscious perception generated postural
reactions. Foisy (2015) confirmed that plantar inserts with a 3- millimeter-thick plantar insert, either a Medial or a Lateral Arch Support,
had an influence upon postural and oculomotor control in a different
way depending on the part of the foot sole being stimulated. Recently, Viseux and al (2019a) demonstrated that putting a than less than
one-millimeter-thick plantar insert under the big toe alter the posturalcontrol, putting a six-millimeter-thick plantar insert does not . In a review they (2019b) show that he foot is the direct interface between
the body and the ground during practice and plantar cutaneous information contributes to postural control. This cutaneous feedback isprovided by lowthreshold mechanoreceptors that are highly sensitive
to low mechanical stimuli applied to the skin of the foot. The mechanical stimulation of plantar cutaneous receptors with thin wedges (<3 mm) can improve postural control. We have also demonstrated thatthin plantar stimulations improved chronic low back pain (Villeneuve& al 2011)
In conclusion we can assume that the neurophysiological model
used in posturologie seem more efficient than the biomechanical model used in podiatry and manual therapy. Neurostimulation locations
are indeed an important point: postural insoles or manual therapy
must be adapted and used in function of the postural clinical evaluation.
Bibliography
Barber ED. Osteopathy complete. Hudson- Kimberly: 1898.
Bourdiol R.J., Capelus F., Ngyen Tan H. Hatoum P. 1980 – Pied et statique.
Maisonneuve, Paris
Janin M, Dupui P. The effects of unilateral medial arch support stimulation on plantar pressure and center of pressure adjustment in young gymnasts. Neurosci Lett. 2009 Sep 25;461(3):245-8
Janin M. Toussaint L. Variation du centre de pression lors de stimulations
par éléments antérieurs d’orthèse. Nouvelles méthodes de traitement dusignal posturographique Michel Lacour Solal 2004, 153-166
Jarvis HL, Nester CJ, Bowden PD, Jones RK. Challenging the foundationsof the clinical model of foot function: further evidence that the Root model
assessments fail to appropriately classify foot function. J Foot Ankle Res.
2017 Feb 3;10:7.
Kavounoudias A, Roll R, Roll JP. The plantar sole is a ‘dynamometric map’for human balance control. Neuroreport. 1998 Oct 5;9(14):3247-52.
Leporck A.M. Modification unilatérale des pressions plantaires. Enregistrement stabilométrique et podométrique. « Pied équilibre et mouvement» (Ed Villeneuve Ph et Weber B), Masson Paris 2000 72-77
Nakajima T, Sakamoto M, Tazoe T, Endoh T, Komiyama T. Location specificity of plantar cutaneous reflexes involving lower limb muscles. Exp Brain
Res. 2006 Nov;175(3):514-25.
Okubo J., Watanabe I., Baron J.B. (1980). Study on influences of the plantar mechanoreceptors on body sway. Agressologie, 21, D: 61-70
Parreira RB, Villeneuve P. Contribution of Neural Manual Therapy in Perineal Pain. World J Phys Rehabil Med. 2017; 1(1): 1003.
Priplata AA, Niemi JB, Harry JD, Lipsitz LA, Collins JJ. Vibrating insoles andbalance control in elderly people. Lancet. 2003 Oct 4;362(9390):1123Root M, Orien W, Weed J, Hughes R. Biomechanical examination of thefoot. 1 edn. Los Angeles: Clinical Biomechanics Corporation; 1971.

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Sanzarello I, Merlini L, Rosa MA, Perrone M, Frugiuele J, Borghi R, Faldini
C. Central sensitization in chronic low back pain: A narrative review. J Back
Musculoskelet Rehabil. 2016 Nov 21;29(4):625-633.
Villeneuve P, Villeneuve S. L’épreuve posturodynamique : Description, interprétation et évolution. Alain Scheibel, Françoise Zamfirescu, Pierre Marie Gagey, Philippe Villeneuve. Pratiques en posturologie. Elsevier Masson
2017 105-118
Villeneuve P. Dysfonctions neurales, algies posturales et neurostimulations manuelles.In:WeberB,VilleneuveP.Clinicalposturology.Understanding,Evaluating, Relieving Pain. Paris: Elsevier Masson; 2012. p.142-67.
Villeneuve P. Dysfonctions neurales, algies posturales et neurostimulations manuelles.In:WeberB,VilleneuveP.Clinicalposturology.Understanding,Evaluating, Relieving Pain. Paris: Elsevier Masson; 2012. p.142-67.
Villeneuve Ph, Ceci LA, Parreira RB, Ribeiro LG, Hosni AP, Rolão MPP,
Camargo Gomes J, De Oliveira TB, Silva Pereira MC, Salgado ASI, Kerppers
III..Analysis of the NPT effect in women with chronic LBP: a pilot study.
MTP&RehabJournal 2017 1-9 Villeneuve Ph, Ehring C, Kurzawa S, Weber B.
Plantar orthotics for patients with chronic low back pain (CLBP) decreases
pain and improves spine function and mobility. Scientific testing of orthotic
devices. 2011
Villeneuve Ph. Apport du traitement manuel neural dans la douleurchronique. Du reboutementàl’essordesneurosciences.Larevuedel’ostéopathieN°3-2:2012p27- 34
Villeneuve Ph.
Douleurs liéesauxdysfonctions
discalesetapportdele Posturothérapie NeuroSensorielle. L’ostéopathe Magazine N°32 2017 24-25 Villeneuve Ph. L’épreuve posturo-dynamique. In Entrées du Système PosturalFin. Sous la direction de Gagey P.M., & Weber B. Ed Masson Paris 51–56,
1995 VilleneuvePh.,1990. Cinquième leçon de Posturologie . In les huitleçons de PosturologieGageyP.M.,BizzoG.,BonnierL.,GentazR.,GuillaumeP.,MarucchiC., Villeneuve P. Ed Association Française dePosturologie
Viseux F, Barbier F, Leteneur S., Lemaire A, Charpentier P, Villeneuve P.
How the stimulation of plantar cutaneous receptors can improve posturalcontrol? Review and clinical commentary. Neurophysiologie Clinique/Clinical Neurophysiology (2019) 49, 263—268
Viseux F, Lemaire A, Charpentier P. Contribution of NeuroSensory Posturotherapy in the management of specific chronic pain syndrome. Neurophysiologie Clinique Volume 48, Issue 3, June 2018, Page 139
Viseux F, Villeneuve P, Barbier F, Parreira R, Lemaire A. Role of the great
toe to improve postural control in elite women handball players. Neurophysiologie Clinique. Volume 49, Issue 3, June 2019, Page 197
Viseux FJF, Villeneuve P, Mora A, Charpentier P, Mulliez T, Barbier F, Salgado ASI, Martins DF, Lemaire A. Chronic low back pain: considerations,clinical overview and hypothesis for neurogenic disc pain. Review. Submit
European Journal of Pain

HOW AYURVEDA TREATS CHRONICINFLAMMATION
Dr.Vijay Carolin B.A.M.S., MSc
Ayurveda Doctor with B.A.M.S. degree from University of Kerala, India and Postgraduation in Drug
Research, Development and control, from University of Barcelona
President of the International Ayurveda medical
Association, Barcelona, Spain

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BOOK OF ABSTRACTS | 12th European Congress of Integrative Medicine · 1st International Symposium on Integrative Health and Education

Chronic inflammation is a known cause of various cancers and metabolic diseases. A comprehensive solution for long term control andcure of chronic inflammation is lacking in the current therapeutic scenario of modern allopathic medicine.
Chronic inflammation is present in most of the autoimmune diseases like Rheumatoid Arthritis, Crohn´s disease, Fibromyalgia, Multiple
Sclerosis, Pulmonary Fibrosis etc.
Ayurveda, the classical medical system of India, which has beenused for more than 5000 years with success, has some important
perspectives, which can be used to control and cure chronic Inflammation.
According to Ayurvedic medicine, Chronic inflammation compares
to Ama. Diseases can have both Ama and Nirama (without inflammation) stages. Ama stage has to be diagnosed, if present, and suitably treated, before employing the normal Ayurveda treatment protocols.
Ama is a result of the body´s derailed nutrition and can be corrected by employing very simple herbs, physical therapies and diet. Pain,
weakness, fatigue, acute symptoms, oedema etc., can be controlled
and cured in very short period by employing the anti-inflammatory(ama pachana) regimen of Ayurveda.
I would like to present a few cases of chronic inflammation managed successfully using Ayurveda.

‘inwards’ one can direct the vibrations of one’s own voice to specificparts of the body. Listening and feeling until the voice enters in resonancewith that specific part of the body, ‘feeling’ the anatomy of the
body through the vibrations of the voice.
The voice as an alliance in processes of personal and spiritual development and in theprevention and healing of the physical health of the participants aswell as their patient’s.

ACUPUNTURE WORKSHOPWORKSHOP OF MIOFASCIAL TRIGGER
POINTS AND LASER THERAPYPart I
How different experts treat same joint pain with Acupunture
We know in acupunture we use different methodologies to threat
samepathologies.
This workshop will be a practical review about how to threat different location of joint pain with different and expertprofessionals
The idea is to have an open workshop between the experts andattendants
We will have several beds where We will see different clinics views
to treat knee pain, shoulder pain and elbowpain…

Part II
Pediatrics in Acupunture
How to use acupunture in children successfully and withoutpain
ChildrenPhysiopathology
How to explore the children, the importance of thepalpation.
Techniques,Material
The acupunture point inchildren
Moxibustion, time to use andmethod
Overdose in childrenacupunture

WELLNESS AND HEALING THROUH THE
VOICE AND THE SOUNG.
Kistemaker J (Puntadecouso/SP)
In this workshop one learns how to use sound and the voice as an
intimate and personal instrument to strengthen one’s natural health.
The voice as a mirror of the physical, emotional and energetic
tensions and blockages accumulated in the physical body. Singing

WORKSHOP 06. TOWARDS A GUIDEFOR PREVENTING OF EXPOSURE TO
ENDOCRINE DISRUPTORS
Dr. Nicolás Olea. Doctor in medicine Nicolas Olea,
expert in epidemiology and specialized in Healthand Environmental Research, will propose in thisworkshop the guidelines to prevent alarming exposure to endocrine disruptors in our society.

Myofascial pain syndrome is the set of sensory, motor andautonomic symptoms caused by trigger points and high prevalence. The myofascial trigger points were described in 1949 by
Travell and Simons, they defined it as a hyperirritable area in askeletal muscle associated with a palpable hypersensitive nodule, located in a taut band, the area is painful to compression andcan lead to referred pain characteristic, hypersensitivity to thereferred pressure, motor dysfunction and vegetative reactions.
They described the mechanisms of activation, perpetuation andunblocking of them. They developed maps showing the trigger
points of each muscle and its referred pain pattern.
To understand this syndrome, it is important to understand thefascial system, its alterations and implications in pain. For this
it is important to know the neurophysiology of pain, mainly inchronic pain and the concept of central sensitization, which isan increase in the neuronal response to painful and non-painfulstimuli, where there is an activation of the nociceptors that leads
to the appearance of myofascial trigger points. In the laser workshop, a working protocol is developed where the location andpalpation of the key points of the trigger is carried out, mainly
we will search at the abdomen and its relations with the trigger
points of the sole of the foot.
The concept of ways will be explained, and it will be shown
how we can unblock any trigger point of the body from the soleof the foot, we will do it by applying laser therapy. The application of the laser for the release of myofascial trigger points isa novel therapy, and very interesting because it is painless andnon-invasive, unlike other widely used therapies for the treatment of this syndrome.
A single session is enough to unblock the trigger point and thepain of the patient immediately disappears, although it is impor-BOOK OF ABSTRACTS | 12th European Congress of Integrative Medicine · 1st International Symposium on Integrative Health and Educationtant to know the causes of perpetuation to prevent recurrence.

GUT MICROBIOTA AND CANCER,
THE IMPORTANCE OF LIFESTYLES:DESIGNING A PROJECT.
Sanchez C (Madrid/ ES)
All of us are provided with a unique gut microbiota profile thatplays many specific and beneficial functions. We have a balancestablished, and when it is disrupted we call it dysbiosis. This plays
an important role in many diseases including cancer. Changes in
our lifestyle involves changes in our gut microbiota, implicating
future prevention and treatmentstrategies.
Key points:
1 Gut microbiota: the5W
Who, What, When, Where and Why. Intoduction to the worldof the gut microbiota
2 Microbiota, inflammation anddisease
Mechanisms correlating microbiota, host immune system andthe development of different diseases.
3 Healthydiets
Discussion about the theorical implication of healthy diets. A
review of the literature: plant-based (vegetarian/vegan), ketogenic and mediterranean.
4 Cancer andmicrobiota
What we know until now. Future strategies.
5 Designing a project and Q&Around

69

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POSTERSBOOK OF ABSTRACTS | 12th European Congress of Integrative Medicine · 1st International Symposium on Integrative Health and Education

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BOOK OF ABSTRACTS | 12th European Congress of Integrative Medicine · 1st International Symposium on Integrative Health and Education

Title: Mindfulness as a Tool in Primary
Care
Margarita Villar Fidalgo1, Cristina Serrano Quiles2
1
Atencion Primaria. Sermas
2Instituto de Técnicas Holísticas, Qi
Many of the patients who attend Primary Care consultations withaffective disorders such as anxiety and/or depression actually present
stressful situations, due to a work, family or couple problem.
Mindfulness is effective in reducing stress and improving the qualityof life.
OVERALL OBJECTIVE:
To evaluate the efficacy of Mindfulness in anxiety and/or depression to reduce the intake of drugs and the return to an active workand social life.
MATERIAL AND METHODS:
Study population:
Adult patients from Primary Care consultations with anxiety and/or depression.
Sample size: 19 patients in total divided into 3 workshops conducted over 3 years.
Methodology:
Eight weekly sessions of 120 min according to the MSC training
program (Mindful Self-Compassion. Christopher K. Germer and Kristin
Neff), 20 minutes a day of practice at home for the first 8 weeks andthen maintaining this frequency through time.
Follow-up consultation for 1 year, measuring both activity and drug
consumption at 6 months and one year.
RESULTS:
WORK Currently in work On sick leave
Does not work
Start 982
6 months
170
2 (1 is studying)
1 year 18
0
1
DRUGS 0 drugs 1 drug
Start 39
1 year 11
7

2 drugs 3+ drugs
5
2
0
1

YEARS OF TREATMENT
10+ years 5+ years 4+ years L e s sthan 1 year
Start 32
1
13
CONCLUSIONS:
6 months after the workshop all patients were active and had evenregained social relationships that they did not have before.
A year after the workshop almost 60% of patients no longer took
any medication.
In view of the results obtained, it can be said that Mindfulness is avery efficient tool to use in Primary Care.

Correspondence to:Margarita Villar Fidalgo
E-mail: mvifidalgo5@gmail.com

Title: Naturopathic Treatment and Complementary Medicine in Surgical Practice
Lederer Ann-Kathrin1, Müller Alexander1,
Schmucker Christine2, Fichtner-Feigl Stefan3, Huber Roman1
1
Center for Complementary Medicine, Institutefor Infection Prevention and Hospital Epidemiology, Medical Center - University of Freiburg
2
Institute for Evidence in Medicine (for Cochrane
Germany Foundation), Medical Center-University
of Freiburg
3
Department for General and Visceral Surgery,
Medical Center - University of Freiburg
BACKGROUND:
Many patients in Germany use naturopathic treatments and complementary medicine. Surveys have shown that many also use themas a concomitant treatment to surgery.
METHODS:
Multiple databases were systematically searched for systematic reviews, controlled trials, and experimental studies concerning the useof naturopathic treatments and complementary medicine in the management of typical post-operative problems.
RESULTS:Of the 387 publications identified by the search, 76 fulfilled theinclusion criteria. In patients with abnormal gastrointestinal activity,
acupuncture can improve motility, ease the passing of flatus, andlead to earlier defecation. Acupuncture and acupressure can reduce
postoperative nausea and vomiting, as well as pain. More-over,aromatherapy and music therapy seem to reduce pain, stress and anxiety and to improve sleep. Further studies are needed to determine
whether phytotherapeutic treatments are effective for the improvement of gastrointestinal function or the reduction of stress. It also
remains unclear whether surgical patients can benefit from the methods of mind body medicine.
CONCLUSION:
Certain naturopathic treatments and complementary medical
methods may be useful in postoperative care and deserve more intensive study. In the publications consulted for this review, no serious
side effects were reported.

Correspondence to:Lederer Ann-Kathrin
E-mail: ann-kathrin.lederer@uniklinik-freiburg.de

BOOK OF ABSTRACTS | 12th European Congress of Integrative Medicine · 1st International Symposium on Integrative Health and Education

Title: The effect of acupuncture on jaw
opening range, and temporomandibular
joint, and myofascial symptoms in patients with Temporo- Mandibular Disorder(TMD): A Randomized controlled trial
Avshalomov David
1
Bnai Zion Medical Center
1

Background: Temporo-Mandibular Disorder (TMD) are common
musculoskeletal conditions in the maxillofacial area and have a multifactorial etiology. The conventional treatment of TMD includes night splint, pharmacological and psychological therapy, occlusal (bite)
adjustment, physical therapy and more. Yet these treatments are
relatively limited in their effectiveness. Several studies have showna positive effect of acupuncture on TMD symptoms. However, thesestudies focused on subjective outcomes, without assessment of jaw
opening range. Our goal in this study is to conduct a randomized controlled trial) which will examine the effect of acupuncture on improving jaw-opening range as well as reducing TMD symptoms.
Methods
In this randomized controlled trial, study participants will include
patients admitted to the Oral Medicine and Maxillo-facial Unit anddiagnosed with TMD. Patients will be randomized to acupuncturewith standard care or standard care only. Acupuncture will be provided once weekly for 12 weeks, and treatment approach will be based
according to traditional Chinese medicine syndrome diagnosis. Standard care will include Occlusal (Bite) adjustment, and physical therapy. Main study outcomes will include TMD symptom questionnaireand jaw range as assessed with ruler measurement. In addition, an
acupuncture safety questionnaire (acuAE) will be used to assess acupuncture safety. At baseline, 6, and 12 weeks, patients will undergo
evaluation of oral and maxillofacial motion ranges, pain and discomfort assessment, and examination of the muscles that are relevant to
TMD. Paired t-test or Wilcoxon tests will be used for statistical analysis
together with descriptive statistics.
As part of a pilot toward the above study, 14 patients were treatedwith acupuncture, most receiving at least 12 treatments. Interim analysis of the pilot will be provided on the poster.

Correspondence to:
Avshalomov DavidE-mail: avshalomov8@gmail.com

73

Title: Effect of repetitive transcranial magnetic stimulation on pain and thermal
sensitivity in Myofacial Pain Dysfunction
syndrome (MPDS)
Garima Sharma Renu Bhatia1, Suvercha Arya1,
Shalini Gupta1
1
All India Institute of Medical Sciences, New Delhi,
India
Objective: The aim of the study was to understand the effect ofrepetitive Transcranial Magnetic Stimulation (rTMS) on pain status,
maximum mouth opening and thermal sensitivity of masseter muscle
in Myofacial Pain Dysfunction Syndrome patients.
Material and Methods: It was a randomised control trial, the study
was conducted at a tertiary hospital in New Delhi, India. Twenty(Males=5, Females=15) MPDS patients aged (40.9 ± 10.8 years) wererecruited based on laskin’s criteria. They were allocated to real andsham rTMS groups. Patients with other systemic illness, neuropathy,
epilepsy, history of head trauma, metal implants, pacemakers, pregnancy etc were excluded.
MPDS patients reported severe pain, markedly reduced mouth
opening and sensory deficit at masseter at baseline.
Repetitive TMS (10Hz frequency) therapy at 90% of their Resting
Motor Threshold (RMT) at motor cortex for 7 days.
To evaluate the pain status Visual Analog Scale (VAS), Maximum
mouth opening (MMO) and McGill Pain Questionnaire- short form
(MPQ-SF) were utilized. Thermal sensory testing was performed using Neurosensory analyser TSA II, at masseter (test site) and at hand(reference site)
Analysis: Data was analyzed using GraphPad Prism version 8.0.
D’Agostino-Pearson and paired t-tests were applied for determining
normality and for comparison between the groups respectively.
Results: The data had a Gaussian distribution. Significant decreasein pain {(VAS) and MPQ-SF score (p<0.000001)}, thermal pain thresholds (Cold and hot) (p=0.0005) was observed after real rTMS therapy group compared to sham group. Patients who recieved real rTMS
therapy had significant improvement in maximum mouth opening(p=0.0028).
Conclusion: High frequency rTMS therapy on motor cortex is effective in ameliorating MPDS pain and correcting sensory deficit. Henceit may be considered as a therapeutic intervention in Myofacial pain
dysfunction syndrome.

Correspondence to:
Garima Sharma Renu Bhatia
E-mail: garimasharma9191@gmail.com

74

BOOK OF ABSTRACTS | 12th European Congress of Integrative Medicine · 1st International Symposium on Integrative Health and Education

Title: Implementation of a Multi-Professional Anthroposophic Treatment Concept
in the Geriatrics
Zerm Roland , Berger Dagmar , Magerstädt Roland2, Hohner Heidi2, Girke Matthias2, Kröz Matthias3
1
Researche Institute Havelhoehe (FIH) and Gemeinschaftskrankenhaus Havelhoehe Berlin
2
Gemeinschaftskrankenhaus Havelhoehe3
Researche Institute Havelhoehe (FIH) and Gemeinschaftskrankenhaus Havelhoehe Berlin
12Introduction
The number of people aged over 80 will almost double by 2060.
While at present, the ageing process is often viewed from a deficit-oriented perspective, Anthroposophic medicine (AM) aims to focus on the accumulated life experience and personal development.
These are described by terms such as wisdom of age, goodness, social
competence. AM includes physical, mental and spiritual dimensionsof the human being in diagnostics and therapy. In geriatrics, a multimodal therapeutic approach is generally applied, which is why it
makes sense to broaden it through AM.
Methods
In 2016, on the basis on a literature research a multi-professional
working group in the Gemeinschaftskrankenhaus Havelhöhe developed a comprehensive concept for the treatment of geriatric patients
based on AM. A common understanding of the disease was developed together with all therapeutic professions (doctors, nursing, physio-, eurythmy-, occupational-, music- and speech therapy, logopaedics, massage). Main symptoms, available resources and the resulting
therapy requirements were identified. Finally, a coordinated therapy
concept was developed and subjected to a review process. All nurses
and therapists of the ward were trained in handling external nursing
applications of AM (compresses, rhythmical oil applications).
Results
The result is a manual that can improve the quality of treatment
for geriatric patients and at the same time improve the integrationof specific anthroposophic therapies into everyday clinical practice.
The concept was presented to all employees during a roll-out meetingand steps for implementation were agreed. It has been in use sinceautumn 2017 and already led to increased employee satisfaction.
Among others, a weekly therapy plan was implemented to promote
the patients day/night rhythm. The next step is to evaluate patients
expectations, satisfaction and outcome quality.
Summary
A coordinated therapy concept based on AM for geriatric patientswas developed and implemented inter-professionally. An evaluationof patient satisfaction and result quality is still pending.

Correspondence to:Zerm Roland
E-mail: rzerm@havelhoehe.de

Title: Pelvic Outlet Syndrome: A New Integrative Diagnosis Helps Treatment
Daniela Helena Jurisic MD1, Dante Broglia MD2,
Ivano Colombo PT3, DO Jurisic1
1
Medical College of Wisconsin, AIMFORHEALTH
Integrative Medical Clinic Milano
2Mediperson Medical and Radiologic Clinic
3Gerola Medical Clinic
Objectives:
Pudendal neuropathic pain treatments usually target either endopelvic trigger points or the nerve itself in Alcock’s canal, with little
attention to pelvic stabilization muscles encountered throughout thenerve’s long course. As integrative medicine specialists, we hypothesized that pudendal neuropathy might also result from its impingement
while exiting the lesser sciatic foramen: the pelvic analogue to “thoracic outlet syndrome.”
Material and method:
30 patients with dysesthesia in pudendal distribution were studied.
Pudendal neuropathy was confirmed by EMG, symptomatic for 4-12
years. Ages: 25-60. 18 female, 12 male. Inital MRI confirmed muscle-nerve impingement in the lesser sciatic foramen in all patients.
The same radiologist read all MRI. Treatment included 6-10 posturaland 3-6 osteopathic sessions, each once weekly, to diminish sciatic foramen obstruction, based on individualized physiatric postural analysis and prescription, integrated with MRI findings. No endopelvic trigger point treatments or injections, or alterations in oral medication
were performed during this treatment period. The same physiatrist,
posturologist and osteopath treated all patients.
Analysis
Symptom reduction was measured by VAS and sitting tolerance, at
initial and final therapy,( 12-16 weeks later)
Results
Initial VAS: 6-10. Final VAS: 0-4. No patients had increased pain.
Average pre-treatment sitting tolerance : 10’-60’. Post-treatment: 60’360’.
Discussion
Pudendal nerve dysesthesias are often severe, and disabling. Alcock
canal injections and endpelvic massage give variable success. The
sacral plexus origin, with exo- and endopelvic distribution demands
an integrative, rather than vertical specialty-based approach. An interprofessional and analogic, integrative thought process toward upperand lower girdle nerve-impingement anatomy can provide the possibility of successful treatment.
Conclusion:
This diagnosis “pelvic outlet syndrome” and its integrative treatment are successful and , to our knowledge, new. . We propose it for
use also by others who treat these complex patients.

Correspondence to:Daniela Helena Jurisic MD, Dante Broglia MD, Ivano Colombo PT,
DO Jurisic
E-mail: danielajurisic@hotmail.com

BOOK OF ABSTRACTS | 12th European Congress of Integrative Medicine · 1st International Symposium on Integrative Health and Education

Title: Cytology-based Circulating-Tumour-Cell (CTC) Screening Test improvesdetection of prostate cancer

75

TITLE: MULTIMODAL PROGRAM OFHEALTH PROMOTION AND QUALITY OF
LIFE BASED ON HEALTH THEORY BY MO‐KICHI OKADA: CASE REPORTS

Karin Ried1, Tasnuva Tamanna1, Sonja Matthews1,
Joan King1, Peter Eng1, Avni Sali1
1
National Institute of Integrative Medicine (NIIM),
Melbourne, Australia

Eny Marcia Ruggerini1, Ivna Maia Fuchigami1, Ricardo Monezi1
1
Spirituality and Health Department – M.O. Foundation, São Paulo, Brazil

Objectives
Evaluation of the cytology-based ISET-CTC (Isolation-by-Size-of-Epithelial-Circulating-Tumour-Cells, Rarecells, France) blood test as ascreening tool for the early detection of cancer.
Background
Circulating-Tumour-Cells (CTC) provide a blood biomarker for early
carcinogenesis, cancer progression and treatment effectiveness. An
increase in CTCs is associated with cancer progression, a CTC decrease
with cancer containment or remission.
The ISET-CTC Test is a clinically validated cytology-based blood test
superior in its sensitivity and specificity to identifying cancer cells
compared to other non-cytological marker-based CTC tests, and has
been featured in >80 peer-reviewed articles published worldwide
over the last 20 years.
Methods
This observational study compared CTC count to cancer status andcancer risk, by monitoring treatment effectiveness in cancer patientsand by screening for CTC in asymptomatic patients with risk factors,
including family history of cancer. In a subgroup of male patients withpositive CTC count, we also undertook immunohistochemistry (IHC)
assays with prostate specific antibodies.
Results
To date, NIIM has undertaken more than 1800 CTC tests, half ofwhich were screening requests with CTC detected in 50% and early cancer in 25%. CTC count was directly correlated with cancer risk
and cancer status. Asymptomatic males with normal Prostate-Specific-Antigen (PSA) levels and a positive CTC count were followed up
by PSMA-PET (prostate-specific-membrane-antigen-PET) scans, withan increased uptake in the prostate being indicative of early prostatecancer. Additionally, IHC assays with PSA and Prostein antibodies confirmed CTC origin from the prostate.
Conclusions
Cytology-based ISET-CTC screening provides a highly sensitive
non-invasive test for early detection of cancer, with higher CTC counts
being associated with higher risk of malignancy. We found CTC-countto be a better predictor for early prostate cancer than standard PSA
blood testing. Early detection of cancer risk supports early interventions and preventative actions. Integrative lifestyle and nutritional
therapies can reduce the CTC count and therefore cancer risk.

Objectives: Based on the principles established by Mokichi Okada(MO) in his Theory of health, set forth in the 1940’s, the present work
aims at reporting the results of three cases of volunteers participating in a multimodal program of health promotion (MPHP) where
they were taken care of through the practice of laying on of hands
called Johrei, dietary education guidelines based mainly on organic
food consumption, and participation in art activities in order to widen
their awareness of life, its senses and meanings. Materials and methods: Cases: 1) E.C.P., female, 62 years old: breast cancer relapse withmetastasis in bones and liver. 2) L.C., male, 56 years old: liver cancer.
3) A.O., female, 73 years old: high cervical intraepithelial neoplasia.
The volunteers continued their conventional medical treatment and,complementarily followed the MPHP and quality of life (QOL) basedon the theory of health according to MO. Analysis: clinical follow-up,
laboratory test results and images. Results: Complete remission of tumors, with an average time of a 10 month-participation in the MPHP
and QOL based on the theory of health by MO. Discussion: The individuals led their actions towards health recovery and promotion as
well as of QOL, especially by getting and practicing the laying on ofhands intensively, in Johrei mode, and committing themselves to follow a proper food education, based on the intake of organic food. Several articles report the beneficial effects of that behavior, but sporadically. The pioneer aspect of this research was health recovery within amultimodal and integrative perspective, allowing the three volunteers
the remission of their tumors and, above all, the improvement of their
QOL. Conclusions: The MPHP and QOL based on MO’s health theory
indicates its application in cancer treatment, promoting health recovery and increasing levels of QOL.

Correspondence to:
Karin Ried
E-mail: karinried@niim.com.au

Correspondence to:
Eny Marcia Ruggerini
E-mail: eny.ruggerini@fmo.org.br

76

BOOK OF ABSTRACTS | 12th European Congress of Integrative Medicine · 1st International Symposium on Integrative Health and Education

Title: Feasibility and Efficacy of a Writing
to Heal workshop within a Single Medical
CenterTitle: Remission of cardiorespiratory insufficiency and apnoea syndrome throughmicronutrition

Denise Millstine, MD Millstine1, Barbara Thomley1, Sandra Marinella2
1
Mayo Clinic
2
The Story You Need to Tell

Francisco Cardona Burrull1, Mar Blanco Rogel2
1
Consulta privada
2
Universitat Oberta de Catalunya

Objectives: Determine whether clinical wellness workshop focusedon the instruction of writing for healing was feasible, satisfying, andperceived to impact stress, pain, mood, and wellbeing.
Material and method: Participants were invited to attend Writingfor Healing workshops monthly by self-selection and without charge.
Sessions were led by a published author on the topic in person. Subsequent to participation, subjects completed a survey regarding
outcomes. Sessions were held at a single medical center. Inclusion
criteria included willingness to participate, competency in the English
language, and the ability to attend sessions in person. There were no
exclusion criteria.
Analysis: Over a two year period, we had 199 participants with 132
completed surveys.
Results: Survey responses showed “very satisfied” 96.1%, stress“very beneficial” 77.5% and “some benefit” 15.5%, pain “very beneficial” 50.4% and “some benefit” 18.3%, mood “very beneficial” 82.4%
and “some benefit” 13%, general wellness “very beneficial” 83.1%
and “some benefit” 16.2%.
Discussion: Writing therapy is an accessible, low cost, low risk
method of processing emotions, trauma and difficult experiences.
We studied its feasibility within an academic medical center as led bya professional writer, author, and teacher. Patients were overwhelmingly satisfied with the experience while additionally experience reliefof stress, improvement in pain, and benefits to mood even thoughwriting was not necessarily directed at these outcomes. While writing
therapy requires a trained moderator, it is easily scalable
Conclusions: Further research is needed to explore the specificeffects of writing to heal within the context of medical centers, particularly as it might address specific symptoms and struggles patients
commonly face, such as stress and mood disorders.

Correspondence to:Denise MIllstine, MD Millstine
E-mail: millstine.denise@mayo.edu

BACKGROUND/OBJECTIVES: Chronic pathologies have as a common link the excess of oxidative stress and chronic inflammation of
low degree. At the same time, the pathology increases oxidation andinflammation. Basic micronutrients can help stop this vicious cycle.
DESCRIPTION OF THE PROBLEM
A 73-year-old man with cardiorespiratory insufficiency, bronchiectasis and sleep apnoea syndrome. Polymedicated with inhalers, corticosteroids, antibiotics, ACE inhibitors and omeprazole, among others.
Go to a specialist for dyspnoea with minimal effort and poor qualityof life. The patient is given, along with their usual medication, a low
carb diet and micronutritional therapy composed of vitamins A, E, D
and C, vitamins of group B methylated and phosphorylated, minerals
in the form of citrates, coenzyme Q10, R-lipoic acid, N-acetylcysteine
and free essential amino acids.
RESULTS AND DISCUSSION
After a week, the patient significantly improved his general condition, dyspnoea on exertion and oxygen saturation. 15 days later, there was a marked clinical improvement that allowed them to perform
some activities. The progressive deprescription of some drugs begins.
After one month, night home oxygen therapy is withdrawn.
In cardiorespiratory failure and COPD there is a mitochondrial dysfunction that drugs cannot reverse. Micronutrition provides the molecules necessary for mitochondrial functioning, controlling excess free
radicals and improving the production of ATP, an essential moleculefor cardiopulmonary function. Therefore, micronutritional therapy at
optimal doses can help reverse chronic situations.
CONCLUSION
Patients with cardio-respiratory failure and COPD have few alternatives for treatment outside bronchodilators, diuretics, corticosteroids
and treatment with CPAP and/or continuous home oxygen therapy,
with progressive clinical and functional impairment. Micronutrition isshown as a useful adjuvant nutritional treatment to reduce drugs andimprove the evolution of the pathology.

Correspondence to:Francisco Cardona Burrull
E-mail: consulta@doctor-cardona.com

BOOK OF ABSTRACTS | 12th European Congress of Integrative Medicine · 1st International Symposium on Integrative Health and Education

Title: Micronutrition modifies the evolution of a patient with terminal liver failure
Francisco Cardona Burrull1, Mar Blanco Rogel2
1
Consulta privada
2
Universitat Oberta de Catalunya
BACKGROUND/OBJECTIVES: Advanced liver failure is one of thediseases with the worst prognosis, especially when associated withrenal failure.
DESCRIPTION OF THE PROBLEM
A 79-year-old woman with hepatic (cirrhosis) and renal insufficiency, with frequent oedematous ascites decompensations. The patient
requires weekly paracentesis of ascites fluid. She is prescribed a restrictive diet in carbohydrates and animal proteins (not fish, meat or
dairy). Perform a daily micro-fast of 14h together with micronutritional therapy composed of vitamins, minerals, coenzyme Q10, R-lipoic
acid, omega 3 and 6 fatty acids, essential amino acids, n-acetylcysteine and silymarin.
RESULTS
After 15 days her physical-psychic state improves, and paracentesis are distanced. After 2 months, she no longer needs paracentesis,
although she is still very limited for usual activities. After 4 months,
she improves their quality of life to the point of going out alone anddoing housework, with an almost normal activity life. Renal function
is normalised. She only visits the hospital for check-up every 6 months. After 6 years of stability, she relapses due to an umbilical hernia
operation. She has no strength to move, and she calls the clinic. At thistime, the restriction of animal proteins is further affected, basic micronutrition is maintained with active vitamins, minerals, coenzyme Q10,
R-lipoic acid, omega 3 and 6 fatty acids, essential amino acids, silymarin, silybin, and semi-essential amino acids, nucleotides, choline andmyo-inositol are added. After a month, she feels strong enough andshe physically visits the clinic. She reports having more energy than
before and can resume normal activity.
CONCLUSION
The liver is an organ with great regeneration potential, but to activate it, it needs help. Micro-foods, low-protein diets along with basic
micronutrients help repair, regenerate and control excess tissue oxidation and inflammation.

Correspondence to:Francisco Cardona Burrull
E-mail: consulta@doctor-cardona.com

77

Title: Randomised Study, Controlled with
Placebo To Evaluate The Neuroprotector
Effectiveness Of A Food Supplement In Oxaliplatin Neuropathy
Javier Espinosa Arranz1, Natalia Eres Charles2, Jose
Carlos Villa Guzmán3, Juan Serrano Gandía4, Maribel Saiz Cayuela5
1Servicio de Oncología del Hospital General de Ciudad Real
2
Instituto de salud, medicina y oncología holística
IMOHE
3
Hospital General de Ciudad Real
4
Laboratorios Dietéticos Intersa
5
Laboratorios Dietéticos Intersa
Objectives
Chemotherapy-induced peripheral neuropathy (CIPN) is one of
the most frequent side effects derived from chemotherapeutic treatment. It constitutes an important clinical profile in the cancer patientdue to its high prevalence while also presenting a diagnostic and management difficulty.
Several preclinical studies and clinical trials show that certain natural products can reduce the side effects derived from chemotherapy,
including neurotoxicity.
This paper aims to assess the effectiveness of a food supplement
based on extracts of Bacopa, Melisa, a polyphenolic extract fromwhole Grape and wild Blueberry, as well as vitamins B5 and B6 andthe mineral zinc, in the prevention of acute peripheral neuropathy induced by chemotherapy (NACQ) in patients with colon cancer underadjunctive treatment with oxaliplatin.
Material and method
Trial that includes 30 patients diagnosed with colorectal cancer andinitiating an oxaliplatin-based chemotherapy scheme. It is a randomised, prospective study with two branches. Patients will be randomly
assigned (1:1 ratio) to treatment group A (oxaliplatin and placebo cellulose) or group B (oxaliplatin and dietary supplement). After completing chemotherapy treatment, patients will enter an additional
3-month follow-up period.
Analysis
We use the EORTC QLQ-CIPN20 sensory scale and QQL quality oflife questionnaire to clinically assess chemotherapy-induced neurotoxicity (NACQ), before starting chemotherapy, prior to the start ofeach cycle, subsequently every month and up to three months after
the end of the chemotherapy treatment.
Results and Discussion
Results pending assessment
Conclusions
Conclusions pending assessment.
Correspondence to:
Javier Espinosa Arranz
E-mail: javiere@sescam.jccm.es

78

BOOK OF ABSTRACTS | 12th European Congress of Integrative Medicine · 1st International Symposium on Integrative Health and Education

Title: Reflexology user profile of a private
centre in Catalonia
Eudald Tomás-Esmel1, Irene Pérz-Cáceres1, Yolanda Aparicio1, Yolanda Villacorta1, Neus Esmel-Esmel1
1
Esmel Therapy Center, Tarragona (Spain)
Summary
The objective of this study was to investigate the reflexology user
profile in a private centre and explore the factors related to its use.
Design: Descriptive observational study
Methodology: The sample consists of 300 users, selected by systematic sampling. Data collection was carried out through a self-administered questionnaire with 18 items. The questionnaire usedaddresses, among other items, questions about demographic data,
knowledge of complementary therapies, their use, degree of satisfaction, motivation and sources of information.
The subsequent analysis of the data was done with the statisticalpackage SPSS v. 15.0. A descriptive analysis of the data is performed
expressing qualitative variables frequencies, percentages, and quantitative variables with means and standard deviation. Statistical inference is made with 95% confidence, making confidence intervals
for the mean or proportion according to the typology of the variable
and evaluating the association of two qualitative variables with thechi-square test.
Results: 75.6% of users are aged between 15 and 65. 77% are women. 82% use complementary medicine in combination with biomedicine. 69% of users reside in urban areas with over 40,000 inhabitants. Regarding the level of education, 48% had completed university
studies.
Conclusions: The profile of reflexology users corresponds to a
41-year-old woman, resident in an urban area, who has higher education qualifications and who usually knows and uses other complementary therapies that she integrates with biomedical system. The
main source of information is family and friends. In this study, thethree most commonly used modalities in addition to reflexology,
were flower Bach remedies, kinesiology and osteopathy.

Correspondence to:
Eudald Tomás-Esmel
E-mail: eudald_tomas@hotmail.com

Title: Ramsay Hunt syndrome and Acupuncture, a case study
Isabel Giralt1, Gilda Carvajal1, Albert Garcia2, AnnaFabà1, Betina Nishishinya3
1
Energimed
2
Albert Garcia
3
Betina Nishishinya
The Ramsay-Hunt syndrome presents a vesicular rash in the atrial
pavilion or oral cavity associated with peripheral facial paralysis. The
cause is the involvement of the geniculate ganglion by the reactivation of the varicella-zoster virus, it is the second most frequent causeof nontraumatic peripheral facial paralysis.
The case we present in a 27-year-old woman is an otic case that has
a poorer prognosis for recovery than the Bell’s palsy not linked to thissyndrome.
Conventional treatment with oral acyclovir, analgesics, corticosteroids and eye protection measures began 48 hours after the onsetof symptoms and despite the improvement in facial paralysis at fourweeks was very mild. This slight improvement meant that acupuncture, electro acupuncture, seven-pointed hammer for facial stimulation and Chinese phytotherapy were added to the usual treatment,
thus achieving an increase in the improvement that became almost
complete at 14 weeks after the incorporation of complementary techniques.

Correspondence to:
Isabel Giralt
E-mail: isagiralt@gmail.com

BOOK OF ABSTRACTS | 12th European Congress of Integrative Medicine · 1st International Symposium on Integrative Health and Education

Title: Integrating Cupping Therapy in theManagement of Sudden Sensorineural
Hearing Loss in Meniere’s disease: A Case
ReportZainab Almusleh
1
Hamad Medical Corporation, Doha, Qatar.
1

Objective: 48 year old female with a four-year history of Meniere’s
disease, recurrent tinnitus, episodes of dizziness attacks and fullnessof the right ear. The patient developed sudden sensorineural hearing
loss (SSNHL). The patient received conventional treatment in the formof steroids, diuretics and betahistine. Full physical and otoneurological examinations of the patient were insignificant, but her hearing
test showed typical low-frequency SSNHL. Methods: Patient received
6 sessions of wet cupping therapy (WCT). We measured and closely
monitored the patient’s blood pressure and random blood sugar preand post each WCT session. Result: Pure tone audiometry tests revealed significant hearing improvement across almost all frequencies
almost to normal hearing level. Conclusion: This case presentation is
the first reported treatment of SSNHL using WCT. It adds a new modality of treatment to SSNHL secondary to Meniere’s disease.

Correspondence to:
Zainab Almusleh
E-mail: almusleh70@hotmail.com

79

Title: A young man with neurosarcoidosis:
Importance of oxidant status for pathogenesis and therapy
Hugo Stuer1
1
University of Antwerp Family medicine
A young man with neurosarcoidosis:
Importance of oxidant status for pathogenesis and therapy
Case report
June 2018, a young man asked additional treatment for serious
complaints, two months after been diagnosed with neurosarcoidosis.
The problem started with general malaise and incapacity to work.
Becoming short of breath an X ray was made, followed by CT Scan andbiopsy, leading to the diagnosis. Extreme vertigo appeared followedby facial nerve paralysis.
Reasons for encounter where: vertigo and fatigue, pain of the skull,
shortness of breath, without relief by regular therapy.
Anamnesis revealed an Epstein Barr episode in 2013. One week
before onset of the syndrome, sport activities were extreme with supercooling.
Besides advice on high quality nutrition with vitamine C and daily
amounts of nuts, we started supplements: Magnesium and Sodiumbicarbonate, beer and baker’s yeast, cod liver oil and a mixture of fresh
linseed and pumpkinseed.
As nutriceuticals: Acetylcysteine, Milk Thistle and Withania.
Within three weeks recovery was spectacular, all symptoms disappearing with possibility for working and sporting.
Discussion
Neurosarcoidosis as complication of sarcoidosis is assumed to be
rare. Regular therapy is symptomatic. The cause is unknown. Hypothetically the immune system responds to infectious or chemical
agents. Stress is mentioned.
Since the anamnesis of oxygen debt and supercooling we focussed
on adjuvants for Reactive Oxygen Species (ROS): Zinc and Mg withamino acids, Withania (anti inflammatory), Milk Thistle (antioxidant)
and Acetyl cysteïne (detoxification).
The intake of nuts provides trace elements. Sodium Bicarbonate
has anti inflammatory capacities in endothelial cells, and linseed is
powerful for endocrine reset.
Conclusion
In this case of neurosarcoidosis, after regular therapies, symptoms
continued leading to incapacity for working and sporting. Guided by
the assumed pathogenesis of ROS a program was offered on threelevels: high quality nutrition, food supplements and nutriceuticals,
achieving full recovery within 3 weeks.

Correspondence to:
Hugo Stuer
E-mail: hahohugo@skynet.be80

BOOK OF ABSTRACTS | 12th European Congress of Integrative Medicine · 1st International Symposium on Integrative Health and Education

Title: ‘What can I do?’ A young woman
with heart failure during oncological therapy
Hugo Stuer1
1
University of Antwerp Family Medicine
Case report
For her metastatic Adenoid Cystic Carcinoma of the parotis ACC she
had impressive therapies: operations on parotis, both lungs and liver,chemo-, immune- and endocrine therapies and radiations.
Reason for encounter was discovery of heart failure (ejection fraction EF 23%, brain natriuretic peptides BNP 1330) communicated as‘irreversible’ with possible serious complications.
She followed regular approach: increasing dose for Betablocking,Ace inhibition and diuretics, plus progressive briskwalking.
Besides advice on high quality nutrition with awareness on vitamine C and nuts we started supplements: Sodiumbicarbonate, beer andbaker’s yeast, cod liver oil and a mix of linseed and pumpkinseed
As nutriceuticals: Magnesium with amino acids and Omega³ oil(cellmembrane), co-enzyme Q10 (mitochondrial energy), Zinc(anti oxidant), Milk Thistle (detoxification), Curcuma (anti inflammatory) and
Hawthorn (Inotropic).
After 2 months EF raised to 35%, BNP dropped to 400.
After 8 months: EF 55%, BNP normalized.
Discussion
Explanations for Heart failure, common in oncology, are: Chemo-Radio-Immuno-and Endocrine therapies, Protonpumpinhibitors,
Low bodily temperature, Insufficient sleep quality with lack of parasympathetic recovery.
A multimodality approach categorizes the program on 3 axes: regular therapies, adjuvants and personal elements.
Standard medication stayed on low dose due to symptomatic low
blood pressure.
Adjuvants were divided in high quality nutrition, food supplements
and nutriceuticals supporting mitochondrial energy, oxidation, detoxification, inflammation and inotropy.
The verdicts ‘irreversibility’ and ‘dangerous’ are important, seen the
prognostic role of the parasympathetic system in cardiology and oncology. Transition came by answering the initial question: ‘What can
I do?’
Conclusion
Adjuvants have many sided benefits for heart failure with evidence
in therapy and prevention.
Despite the verdict almost full recovery was achieved in <8 months.
Integrative communication is required: useful tool is a multimodality model with 3 axes, regular, adjuvant, and personal.

Correspondence to:
Hugo Stuer
E-mail: hahohugo@skynet.be

Title: Kyolic aged garlic extract improves
blood pressure, arterial stiffness and gut
microbiota in hypertensives: The GarGIC
trial
Karin Ried1, Nikolaj Travica1, Avni Sali1
1
National Institute of Integrative Medicine (NIIM),
Melbourne, Australia
Objectives
To assess the effect of Kyolic aged-garlic-extract on blood pressure,arterial stiffness, inflammation, and gut microbiota.
Background
Kyolic-aged-garlic-extract has demonstrated effectiveness in reducing blood pressure in a large proportion of hypertensive patientssimilar to first-line standard antihypertensive medication. High bloodpressure has been linked to gut dysbiosis, with a significant decreasein microbial richness and diversity in hypertensives compared tonormotensives. Furthermore, gut dysbiosis has been associated withincreased inflammatory status and risk of cardiovascular events.
Methods
A total of 49 participants with uncontrolled hypertension completed
a double-blind randomised placebo-controlled trial of 12-weeks,
investigating the effect of daily intake of aged-garlic-extract (1.2g
containing 1.2mg S-allylcysteine) or placebo on blood pressure,pulse-wave-velocity and arterial stiffness, and gut microbiota.
Results
Mean-blood-pressure was significantly reduced by 10±3.6 mmHg
systolic and 5.4±2.3 mmHg diastolic compared to placebo. Vitamin-B12-status played a role in responsiveness to garlic on bloodpressure in 17% of patients. Kyolic garlic significantly lowered
central-blood-pressure, pulse-pressure and arterial-stiffness by anequivalent of 5 years’ of ageing (p<0.05), important risk factors for
cardiovascular morbidity. Furthermore, aged-garlic-extract improved
gut-microbiota, evident by higher microbial richness and diversity
with a marked increase in Lactobacillus and Clostridia species after 3
months of supplementation.
Conclusions
Our trial suggests Kyolic-aged-garlic-extract to be effective in significantly reducing blood-pressure in patients with uncontrolled
hypertension, has the potential to improve central hemodynamics
including arterial stiffness, and gut microbial profile. Aged-garlic-extract is highly tolerable with a high safety profile as a stand-alone or
adjunctive antihypertensive treatment, with beneficial effects on avariety of cardiovascular risk factors and gut health.

Correspondence to:
Karin Ried
E-mail: karinried@niim.com.au

BOOK OF ABSTRACTS | 12th European Congress of Integrative Medicine · 1st International Symposium on Integrative Health and Education

81

Title: Multimodal Program of Health ProTitle: Mental illnesses and the use of intemotion and Quality of Life based on health grative therapies. Systematic review
theory by Mokichi Okada
Eny Marcia Ruggerini , Ivna Maia Fuchigami , Ricardo Monezi1
1
Spirituality and Health Department – M.O. Foundation, São Paulo, Brazil
1

1

Objectives: Based on the principles established by Mokiti Okada in
his theory of health, set forth in the 1940’s, the present study aims
at reporting the evaluation of a multimodal program of health promotion (MPHP) where the patient is taken care of by the practice oflaying on o hands called Johrei, dietary education based mainly on
the intake of organic food and participation in art activities in order
to widen his/her awareness of life, its senses and meanings. Materials
and methods: It had been established as targets patients with chronic diseases. 27 individuals were distributed and they started: 1) thepractice of Johrei, being cared of and also committed themselves totake care for other people through this practice; 2) started a systematic diet, where the consumption of organic foods and proper methodsof food preparation were recommended; 3) activities concerning art
appreciation and preparation such as ikebana. Before the beginningand three months later, quality of life (QOL) levels, spirituality, general health situation, and happiness index were measured. Analysis:
was performed using the SPSS statistical software. Results: After threemonths of participation, the volunteers presented improvements inseveral aspects of QOL, as well as in topics related to their spirituality. Their general health also improved, and it was noticed a significant difference in happiness level. Discussion: The results are muchin accordance with many studies on MPHP, through integrative andcomplementary health resources. The innovative character is the
combination of three modalities that were separately evaluated andshowed effectiveness. The imposition of hands in Johrei modality, theintake of organic food and art practices pointed out their effectiveness in the promotion of integral health. Conclusion: The program indicates its application in the improvement of health and quality of lifeof chronic patients.

Correspondence to:
Eny Marcia Ruggerini
E-mail: eny.ruggerini@fmo.org.br

Carme Porcar Castells1,3, Montserrat Nolla Benavent2, Patricia Tomas Cantos3, Providencia Garcia- Fresneda4
Hospital San Joan, Reus
Hospital Joan XXIII, Tarragona
3
Master Ciències de la Infermeria, URV, Tarragona
4
ABS Riudoms, Tarragona
1
2

Health professionals in our daily practice are presented with unknowns in the proper use of complementary instruments in mental
illness. Can we recommend yoga, reflexology, Bach flower remedies
or Reiki to patients with depression or schizophrenia?
The main objective will be to look for studies with evidence in relation to integrative instruments such as yoga, Reiki, Bach flower remedies and Reflexology in mental pathologies such as depression andschizophrenia.
Bibliographic search in PUBMED and CINAHL with the keywords:
Depression, schizophrenia, yoga, reflexology, Bach flower remedy andReiki. Boolean AND. Full text, in English, Spanish and under 5 years.
Only studies with evidence 1A, 2A or 1B will be analysed.
As results we obtain in PUBMED 166 articles on yoga and depression, of which we highlight 5 of them by presenting the evidence of
our objective. For the words yoga and schizophrenia we find 17 studies of which 1 stands out for its methodology and results. No results
are obtained from the rest.
In CINAHL we obtain 2 studies for the treatment of depression withyoga, without highlighting any and curiously here we find 13 studies
for the use of reflexology in depression, of which one stands out for
its evidence 1A.
We conclude after reading the outstanding articles we can, as health professionals recommend yoga and reflexology to complement thetreatment of depression. In schizophrenia yoga will help us reduce
psychopathology and improve patients’ cognition.
However, the type of yoga used in most studies or the protocol offoot reflexology is not specified. It would therefore be necessary to
improve the line of research in this regard. And of course introduce
other integrative therapies such as Reiki or Bach flower remedies.

Correspondence to:Carme Porcar CastellE-mail: carmetaporcar@hotmail.com

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BOOK OF ABSTRACTS | 12th European Congress of Integrative Medicine · 1st International Symposium on Integrative Health and Education

Title: Opinions of Romanian medical doctors regarding cassic versus online training
on adaptogens
Ramona Jurcău*1, Ioana Jurcău2, Octavian Andercou3
Department of Pathophysiology, Faculty of Medicine, „Iuliu Hațieganu” University of Medicine andPharmacy, Cluj-Napoca, Romania
2Emergency Clinical Hospital for Children, Cluj-Napoca, Romania
3
Department of Surgery II, Faculty of Medicine,„Iuliu Hațieganu” University of Medicine andPharmacy, Cluj-Napoca, Romania
1

Introduction: Adaptogens (AD) are represent subject of researchinterest, also studied in various forms of organizing training courses.
The objective was to assess the opinion of some medical doctors (MD)regarding classic versus online training on AD.
Material and method: MD without AD training, voluntarily responsed to a questionnaire with topics (T): T1 - importance of medical
AD education; T2 - AD use in prevention and therapy; T3 - AD application in medical practice; T4 - AD use in stress; T5 - only classical AD
training (CT); T6 - only online AD training (OT); T7 - combined classicaland online AD training (COT); T8 - what AD themes would be indicated, as OT. This questionnaire was applied before (M1) and after (M2)presenting the benefits of an AD on-line program. Themes T5-T8 wereapplied also to M2.
Results: MD answers to M1: T1 - medical AD education is importantand necessary; T2 - AD may be useful in prevention and therapy; T3 they do not apply AD in their current medical practice; T4 - they would
like to know more about AD use in stress; T5 - 49% preferred CT; T6- 12% preferred OT; T7- 39% preferred COT; T8 - OT favorite themes,
were theoretical. MD answers to M2: T5 - 17% preferred CT; T6 - 12%
preferred OT; T7- 71% preferred COT; T8 - OT favorite themes, wereboth theoretical and practical ones.
Conclusions: 1) Assessed MDs have shown interest in AD training. 2)
MD participants would like to use AD in stress. 3) Combined, classicaland online training on AD, is the most preferred by MD. 4) MD opted
for online training of theoretical and practical themes about AD.

Correspondence to:Ramona-Niculina Jurcau
E-mail: ramona_mj@yahoo.com

Title: Prevalence of health burdens in patients suffering from malignant diseases
revealed by bioresonance – our experience
Antonina Rome1, Tanja Misic2, Dusan Vesovic3
1
Institute for bioresonance and regulative medicine, Ljubljana, Slovenija
2
Military Medical Academy, Belgrade, 11.000, Serbia
3
VISAN -- Sanitary Medical School of Applied Sciences, Belgrade, 11.000, Serbia
Background
Bioresonance machines are designed to assist a body to reduce its
toxins and/or stress load and to help body to go back in balance andthus to heal itself.
Objective
The aim of the paper was to present what health burdens we foundin people diagnosed with neoplasm.
Materials and methods
67 patients of both gender were included in the study (28 – 41,8%
males, and 39 – 58,2% females). Mean age was 41,8+-7,9yrs. They
filled out questionnaire related to presence of diseases in accordance
to International Classification of Diseases 10 (ICD-10). Afterwards they
were tested with german bioresonance apparatus. Statistical analysis
was done by using SPSS v. 17.0.
Results and discussion
7 subjects (10,4%) were diagnosed with neoplasm. In all patients(100%), bioresonance revealed Streptococcus, Staphylococcus, Aspergillus, Candida, aflatoxin, Ascaris, Oxyuris, and mercury. In 85,7%
tested subjects with neoplasm, bioresonance revealed presence of
Adenovirus, Helicobacter, lead, chromium, formaldehyde, lack of selen, zink and vitamin D. Gluten, milk, and pork meat intolerance wasfound in 71,4% tested subjects. The same prevalence was found for Picorna virus, presence of aluminum, thimerosal, and organic solvents.
Presence of EBV and Proteus was revealed in 57,1% subjects. Gluten
intolerance and presence of VZV, HSV, CMV, HPV, Coxackiae, Chlamidia, Salmonela, Mycoplasma, and Pseudomonas were found in 42,9%of tested subjects. All other health burdens were present in less than
30% of tested subjects.
Conclusions
Bioresonance may be very useful tool to reveal presence of healthburdens in subjects diagnosed with neoplasm and may be used concomitant with classical therapy with an aim to clean up body from toxins, bacteria, and fungi. This, in turn, will help and accelerate healing
process. Further studies with bigger sample size are needed to better
clarify this issue.

Correspondence to:Antonina Rome
E-mail: info@institut-brm.si

BOOK OF ABSTRACTS | 12th European Congress of Integrative Medicine · 1st International Symposium on Integrative Health and Education

Title: Mineral deficiencies and food intolerance in patients suffering from chronic
non-communicable diseases revealed bybioresonanceAntonina Rome , Tanja Misic , Dusan Vesovic
1
Institute for bioresonance and regulative medicine, Ljubljana, Slovenija
2
Military Medical Academy, Belgrade, 11.000, Serbia
3
VISAN -- Sanitary Medical School of Applied Sciences, Belgrade, 11.000, Serbia
12

3

Background
Additional to classic therapy, bioresonance is very useful in treating
patients with chronic non-communicable diseases (CnCD).
Objective
The aim of the paper was to present the presence the most prevalent deficiencies we found in people suffering from CnCD.
Materials and methods
67 patients of both gender were included in the study (28 – 41,8%
males, and 39 – 58,2% females). Mean age was 41,8+-7,9yrs. They
filled out questionnaire related to presence of diseases in accordance
to International Classification of Diseases 10 (ICD-10). Afterwards they
were tested with german bioresonance apparatus. Statistical analysis
was done by using SPSS v. 17.0.
Results and discussion
7 subjects (10,4%) were diagnosed with neoplasm, diseases ofblood and blood forming organs had 5 subjects (7,5%) and the same
number of subjects suffered from mental and behavioral diseases;
endocrine, nutritional, and metabolic diseases were diagnosed in 3
subjects (4,5%), diseases of nervous system were present in 4 subjects(6%), 8 (11,9%) subjects suffered from eye diseases, while 14 subjects(20,9%) had ear problems. Diseases of circulatory system were foundin 14 subjects (20,9%), diseases of respiratory system were found in 19
subjects (28,4%), while 28 subjects (41,8%) had problems with digestive system. 31 subjects (46,3%) reported diseases of skin, 21 of them
(31,3%) reported musculoskeletal diseases, while 20 subjects had
problems with genitourinary system. Bioresonance testing revealed
following results: 50 subjects (74,6%) were deficient in selen which
was also true for zinc deficiency. 61 subjects (91%) lacked in vitamin D.
As for intolerance, 83,6% were sugar intolerant, 80,6% were milk andpork meat intolerant, and 79,1% were gluten intolerant.
Conclusions
Bioresonance may be very useful tool to reveal deficiencies andfood intolerance in people suffering from CnCD. This may result indiet change and appropriate dietary supplementation which will help
health improvement.

Correspondence to:Antonina Rome
E-mail: info@institut-brm.si

83

Title: Chickens Breast Meat Enriched With
Propolis And/Or Bee Pollen – Implications
For Human HealthIvan Miskulin1, Ivana Prakatur2, Ivan Vcev3, Matea
Matic Licanin1, Aleksandar Vcev4, Maja Miskulin1
1
Josip Juraj Strossmayer University of Osijek, Faculty of Medicine Osijek, Osijek, Croatia
2
Josip Juraj Strossmayer University of Osijek, Faculty of Agrobiotechnical Sciences Osijek, Osijek,
Croatia3
University of Zadar, Zadar, Croatia
4
Josip Juraj Strossmayer University of Osijek, Faculty of Dental Medicine and Health Osijek, Osijek,
Croatia
Objectives: Propolis and bee pollen belong to a group of natural
substances of animal and vegetable origin with a particularly expressed antioxidant and antimicrobial properties attributed to its phenolic bioactive compounds. Chicken meat can serve as functional foods
enriched with polyphenols. The aim of this study was to produce enriched chicken meat and to determine total phenolic (TP) content inbreast meat of chickens fed with feed mixtures additionally supplemented with various amounts of propolis and/or bee pollen.
Materials and methods: This study was conducted on 200 Ross 308
chickens divided into five groups (control group - C, fed with feed mixture and four experimental groups - E1-E4, fed with following additions to kg of feed mixture: E1 (0.25 g of propolis + 20 g of bee pollen);
E2 (0.5 g of propolis); E3 (1.0 g of propolis); E4 (20 g of bee pollen)). In
breast meat samples the TP content was determined by the Folin-Ciocalteu method.
Analysis: One-way ANOVA and LSD test were used for data analysis.
Results: Mean values of TP content (mg/g) in all groups were:
78.52±13.73 (C); 95.32±10.55 (E1); 87.42±16.84 (E2); 92.94±14.67(E3); 88.56±9.82 (E4). The study showed statistically significant differences between group C and group E1 (p=0.007) and between group
C and group E3 (p=0.020).
Discussion: Recent studies showed that the antioxidant and anti-inflammatory properties of polyphenols may potentially prevent orserve as treatment against many non-communicable diseases (NCDs).
The present study showed that dietary protocol E1 and E3 exerted thelargest incorporation of phenolic compounds in chicken breast meat.
Such innovative technological solution in broilers feeding enables the
production of healthier meat that can be considered functional food.
Conclusions: Created functional food can find its significant place inprevention and integrative treatment of major NCDs in Croatian population such as cardiovascular and cerebrovascular diseases.

Correspondence to:Ivan Miskulin
E-mail: ivan.miskulin@mefos.hr

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BOOK OF ABSTRACTS | 12th European Congress of Integrative Medicine · 1st International Symposium on Integrative Health and Education

Title: Micotherapy and metabolic control
Alberto Sacristán Rubio1, Gualberto Díaz Sáez2,
Luis Hortal Muñoz3
1
Médico de Familia en SportSalud y en Healthing
del Club Reebok. Madrid
2
Médico de Familia en Centro Médico CondeOrgáz. Madrid
3
Médico de Familia en Centro de Salud Gandhi.
MadridBackgroundA 77-year-old woman with hypertriglyceridemia who does notwant to be treated with drugs. Background: Obesity, HBP, Insomnia,
Constipation. Treatment: Irbesartan 150; Bisoprolol 2.5; Eplenorone
50mg, Red Rice Yeast, Omega-3 (eicosapentanoic acid (EPA) ethyl ester (460 mg) and docosahexanoic acid (DHA) ethyl ester (380 mg)) andhigh fibre diet. Father deceased due to MI aged 63.
Description of the problem - Material and method
Patient diagnosed with hypertriglyceridemia, which despite treatment with Omega-3 (DHA-EPA) for several years, has presented a progressive elevation of triglyceride levels, maintaining cholesterol levels.
Discussion
Triglycerides in February-2017 of 220 mg/dl (35-200 mg/dl); in
June-2017: 287 mg/dl; and in February-2018: 302 mg/dl Due to theirbackground and the lack of response with omega-3 to avoid the risk ofcardiovascular accident, in February-2018 treatment begins with 8:1
organic pure extract of Maitake (Grifolia funds) at lunch and dinnerfor 1 month. Subsequently, the treatment continues with a mixture oforganic Maitake 80% powder and 20% extract 2 cap/day, before lunch
and dinner for 3 months. In the following analysis, four months later,
the triglyceride value is 197 mg/dl.
The increase in plasma triglycerides is an alteration that affects ahigh proportion of the adult population in our environment.
Maitake has a hypolipidemic action with reduced triglycerides inanimal models. The mechanism by which it is able to reduce plasmacholesterol is related to the inhibition in the expression of genes involved in the de novo synthesis of cholesterol. In addition, Mitake is able
to promote β-oxidation of fatty acids.
Conclusions
This experience underscores the potential of this approach to reduce cardiovascular risk factors without resorting to drugs and theirconsequent adverse effects, pending confirmation with appropriate
clinical studies.

Correspondence to:Alberto Sacristán Rubio.
E-mail: alberto@fisioalegre.com

Title: Assessment of the tongue featuresassociated with breast cancer using automatic tongue diagnosis System (ATDS)
Lun-Chien Lo1, Po-Chi Hsu1, John Y. Chiang2, JiaMing Chen3, Yin-Lin Chen1, Yi-Ping Chen4
1
School of Chinese Medicine, China Medical University, Taichung, Taiwan
2
Department of Computer Science and Engineering, National Sun Yat-Sen University, Kaohsiung,Taiwan3
Department of Chinese Medicine, Changhua
Christian Hospital, Changhua, Taiwan
4Department of Medical Research, China Medical
University Hospital, Taichung, Taiwan
Objectives
Breast cancer is the most common cancer in women, and survivors
go through a complex and multidisciplinary treatment approach to
the disease. This study investigates discriminating tongue features
to distinguish between breast cancer patients and non-breast cancer
individuals through non-invasive traditional Chinese medicine (TCM)
tongue diagnosis.
Material and method
This study comprised 253 subjects aged ≥ 30 years who were diagnosed with breast cancer from 2012 to 2016 and a total of 161 nonbreast cancer individuals with no specific medical history were enrolled in the control group from 2014 to 2016. The tongue features are
extracted by the automatic tongue diagnosis system (ATDS). A total ofnine tongue features, namely, tongue shape, tongue color, fur thickness, fur color, saliva, fissure, ecchymosis, tooth mark, and red dot are
identified for each tongue.
Analysis
The tongue features in the breast cancer and non-breast cancergroups were analyzed and compared using chi-square test (or Fisher’s
exact) for categorical variables and one-way ANOVA was applied tocompare difference between group means. A p-value < 0.05 was considered statistically significant.
Results
Patients with breast cancer possessed significantly larger covering
area of small tongue (p<0.01), pale tongue (p<0.001), thick fur (p <0.001), yellow fur (p < 0.001), wet saliva (p<0.001) than those of the
non-breast cancer group.
Discussion
This study used objective image analysis techniques to find thatpatients with breast cancer and non-breast cancer individuals havesignificant differences in many tongue features. In the future, further
analysis of tongue features can be made for different stages or different treatment methods of breast cancer patients.
Conclusion
The TCM tongue diagnosis can serve as a preliminary screening procedure in the early detection of breast cancer in light of its simple andnon-invasive nature, followed by other more accurate testing process.

Correspondence to:
Lun-Chien Lo
E-mail: cmulclo@gmail.com

BOOK OF ABSTRACTS | 12th European Congress of Integrative Medicine · 1st International Symposium on Integrative Health and Education

85

Title: The dance of electrons, the forgotten Title: Effects of Chikung On Non-Hodgkin
key to metabolism
Lynphoma Survivors
Title: The dance of electrons, the forgotten key tometabolism
Ana Maria Oliva Brañas1
1Profesional libre, Benidorm, AlicanteIntroduction: Every atom is essentially formed by positive electriccharges (protons) and negative charges (electrons). REDOX reactions
are the classic example of electron exchange between two atoms. Allbiochemistry can be rewritten in electromagnetic code. When we understand physiological processes from an electromagnetic view, concepts are greatly simplified, and other possibilities emerge.
Method and results: The formation of ATP through the Krebs cycle
is conditioned by the existence of an electron pool in so-called cellularrespiration. The different stages of the cycle are based on the exchange of electrons and protons, where electrons pass from higher energy
states to lower energy states, from one atom to another, in a relentlessdance that allows life to occur. The contribution of these electrons,
and the coherence in the endogenous electromagnetic radiation thengo from being a metabolic by-product to be turned into somethingwith which it is possible to interact. When instead of thinking about abiochemical code (with a myriad of different compounds) we introduce electromagnetic concepts, we find a great variety of diagnostic andtherapeutic possibilities that are still very minor and not sufficiently
explored. Certainly, only some areas of medicine use electromagnetic
technologies, widely known for their effects on aesthetics or physiotherapy. That is just the tip of the iceberg of an emerging field thatneeds to be understood from every possible angle.
Conclusion: An electromagnetic view of health and life in generalallows us to understand new keys to health, with both diagnostic andtherapeutic applications of great value. The great advantage is thatelectromagnetic concepts are very simple to apply, have no unwanted
effects and act on the system as a whole, strengthening the body’s
own capacity for self-regulation.

Correspondence to:
Ana Maria Oliva Brañas
E-mail: hola@anamariaoliva.es

Lourdes Diaz Rodriguez1, Keyla Vargas Román2,
Jonatan Fernández Ruiz3, Francisca Hernández4,
Paloma García Marín5, Emilia Inmaculada De La
Fuente Solana61
Departamento De Enfermería. Universidad De
Granada2
Departamento Metodología De Las Ciencias Del
Comportamiento. Fpu. Universidad De Granada
3
Departamento Enfermería. Fpu. Universidad De
Granada4
Hematóloga. Hospital Universitario Virgen De Las
Nieves5
Hematóloga. Hospital Universitario San Cecilio
Granada.Pts
6
Departamento Metodología De Las Ciencias Del
Comportamiento. Universidad De Granada
Objectives: The objective of this study has been to analyse theeffects of an 8-week Chikung program in non-Hodgkin lymphoma
survivors on the quality of life compared to conventional treatment.
Material and method: A controlled pilot study was carried out. All
patients received an information sheet and signed an informed consent before their participation. All assessments were carried out at
the Faculty of Health Sciences of the University of Granada. In theexperimental group, participants attended 16 sessions of 60 minutes
for eight weeks, including 15 minutes of warm-up and stretching, 25
minutes of Chikung exercises, coordination of breathing and flexibility, and 15 minutes of meditation and abdominal breathing exercises.
The control group received the usual recommendations from the corresponding Haematology unit to avoid recurrences. The variables ofanxiety, depression, happiness, fatigue, emotional support, resilienceand sleep were collected before and after 8 weeks.
Results: Of the 25 non-Hodgkin lymphoma survivors recruited at
the Virgen de las Nieves hospital in Granada, 16 completed the program, whose average age was 44.00 ± 11.51 years. The analysis of thevariance showed significant differences in the experimental group
after 8 weeks, presenting a decrease in the state of anxiety (F=6.07
p=0.02) and depression (F=5.46 p=0.03), an increase in social support(F=6.05 p=0.02), emotional support (F=9.12 p=0.01) and resilience(F=5.8 p=0.03), as well as an improvement in sleep (F=10.65 p=0.01)
compared to the control group.
Discussion and conclusions: Participation in a face-to-face 8-week
Chi Kung program can increase resilience in non-Hodgkin lymphoma
survivors, improving psychological status, sleep and social support.

Correspondence to:
Lourdes Diaz Rodriguez
E-mail: cldiaz@ugr.es

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Title: Adherence to allopathic treatment
through complementary traditional medicine
Erika Leyva Mendoza1, Martìn Alberto Rodriguez
Brindis1, Rosa Lilia Garcia Kavanagh1
1
Universidad Anàhuac Oaxaca, Mèxico
Traditional medicine can be a complementary therapy to allopathic
medicine, helping the patient to recover through intervention in theiremotional and mood states, which increases the chances of a comprehensive improvement of the patient. In the case of chronic degenerative diseases, given the time of medical intervention and the joint
aggressiveness of the condition and treatment, this phenomenon ofcomplementarity lends itself to study.
The present study deals with adherence to the allopathic therapy
of a patient with testicular cancer from the intervention of traditionaland complementary medicine. The objective was to determine theimpact of complementary treatment to achieve adequate adherence
to allopathic treatment, improving their quality of life even in times ofgreatest drug crisis.
To this end, a retrospective and cross-sectional descriptive study
was carried out using a case report instrument to record the generaldata of the patient and their state of evolution. To achieve this, testimonies videotaped four years after the case were used. Additionally,
interviews were conducted with both the patient and the traditional
therapist.
It can be seen that the patient recovers adherence to allopathic
treatment after the intervention of traditional medicine by providing
relaxing massage therapy, accompanied by other therapeutic techniques, a diet rich in protein and vegetables, low in fat, carbohydrates
and dairy, along with drinks based on medicinal plants, which improved the mood and physical state of the patient.
It can be concluded that the therapeutic technique of traditional
medicine generates a high level of accompaniment in the patient intheir illness, which contributes to the continuity and adherence to it,
becoming both medicines complementary, with a better result for thepatient.

Correspondence to:
Erika Leyva Mendoza
E-mail: garkav@yahoo.com.mx

Title: Quality of life of people sufferingfrom chronic pain may be significantly improved by the use of natural oils and dietchangeDusan Vesovic1, Dragan Jevdic2, Drago Bozic3, Sonja Gospavic3, Zdravko Vulic4, Aleksandar Jevdic5
1
VISAN -- Sanitary Medical School of Applied Sciences, Belgrade, Serbia
2
ASTROCIT private practice, Vrsac, Serbia
3
Health care Center “1. Oktobar”, Plandište, Serbia
4General hospital, Vrsac
5”Dr Jevdic” private practice, Vrsac, Serbia
Background
Aside other morbidity in older population, presence of chronic pain
may be significant factor that may have negative influence on qualityof life (QoL).
Objective
The aim of this paper was to present the results of intervention
consisting of diet change and natural oils use on QoL in patients withchronic pain.
Materials and methods
37 patients of both gender were included in the study (7 - 18,9%
males, and 30 - 81,1% females). Mean age was 60,7+-11,9yrs. They
filled out questionnaire related to presence and origin of pain before
treatment commence and two months later. Intervention consistedof natural oils use and diet change according to following protocol: I)“Relax Tonic” was applied onto whole body including face; II) when
the skin has become dry, person took a shower and applied “Olje 10”
onto wet skin of whole body and face. This procedure was repeatedonce daily for the period of study. Oils were made by “Planet zdravja”(Slovenia). Statistical analysis was done by using SPSS v. 17.0.
Results and discussion
Results are presented before vs. after the treatment as mean value +- standard deviation. Physical fitness score: 56,2+-9,7 vs. 61,3+6,7 (p=0,000); psychological status score: 57,2+-13,9 vs. 65,3+-11,3(p=0,000); attitude in relation to environment score: 73,6+-14,2
vs. 77,8+-13,3 (p=0,000). Improvement in social relations was alsoachieved, but was no statistically relevant – 66,2+-16,5 vs. 67,6+-16,2(p=0,077).
Conclusions
The study showed that the concomitant use of natural oils and dietchange may help patients suffering from chronic pain to improve quality of life. Significant improvement was revealed in the field of physical health, psychological health, and attitude to environment; improvement was also achieved in the field of social relations, but was no
statistically significant.

Correspondence to:Dusan Vesovic
E-mail: vesovic@rocketmail.com

BOOK OF ABSTRACTS | 12th European Congress of Integrative Medicine · 1st International Symposium on Integrative Health and Education

87

Title: Head lice at school: Natural products Title: Neural therapy in the healing offrom traditional medicine and community chronic ulcer on graft in the scalp
engagement with theatre and music
Renata Campos Nogueira , Anne-Laure Cavin ,Marwah Al-Anbaki1, Bertrand Graz1
1
Antenna Foundation
1

1

Objectives:
To tackle and treat head lice infestations, a public health issue,
through a community program using a recipe derived from traditional
medicine as well as theatre for information and de-stigmatization.
Background
The prevalence of head lice in poor rural communities and urban
slums is estimated to be between 28% and 43% in Brazil. Children areamong the most affected and the stigma surrounding head lice infestation creates a barrier between families who need help and community leaders. In addition, the cost of treatment is not affordable tolow-income families.
Design and methods
We developed a program around a theatre performance involving
the entire school community to put the management of household
head lice under the spotlight. A solution containing water, salt andvinegar, widely used in traditional Brazilian medicine and associatedwith good results in pre-tests was provided and for the first time wasscientifically tested. Evaluation of the program was based on direct
observation and a questionnaire. The study complied with criteria ofStandards for Reporting Qualitative Research (SRQR).
Results
Two hundred and eighty (280) participants, including parents andsiblings of the school children took part in the program. Among them,
24% (N=67) had head lice, with girls representing 85% of cases; 74.7%
of participants infested with head lice were between 4-10 years old;
55.2% (N=37) of participants infested treatment showed no signs ofnits or adult lice after treatment.
Discussions
Although a modest success rate in comparison with formulations
containing chemicals, the building of resistance is unlikely. The use of
a nit comb as a complement to the product’s application will be investigated and may greatly increase the success rate.
Conclusions
The theatre play associated with a well-known and accessible local
product to treat head lice in low-income families gathered a high degree of community adherence.

Correspondence to:Renata Campos Nogueira
E-mail: rnogueira@antenna.ch

Mireia Serrat Bonet1, Martina Gómez Sierra1
1Medicina Integrativa Girona
Objective: To assess the effectiveness of Neural Therapy (NT) in thehealing of a chronic ulcer on skin graft in the scalp, which has not responded to conventional treatment.
Material and Methods: Neural Therapy is a technique developedin Germany that involves the injection of local anaesthetics into theskin, autonomic nerve ganglia, peripheral nerves, scars, acupuncture
points, activation points and other tissues. It is based on the theory
that any trauma, infection or surgery can damage the Autonomic
Nervous System and produce long-lasting alterations in the electrochemical or electromagnetic functions of the tissues, interfering withthe maintenance of homeostasis and the adaptation responses of theexternal and internal environment.
It is an ulcer in the graft area in the scalp, a year of evolution with
progressive growth, where the protocol for the treatment of chronic
ulcers has been followed.
We complete the conventional treatment with NT and acupuncture
points based on the location of the wound and the territory of themeridian involved.
We start NT with weekly sessions and at 4 months every 2-3 weeks.
We perform: local therapy (papules), interfering field therapy: scars;
local and distant acupuncture points of the related meridians.
Material used: 3cc syringe; 20x0.4mm needle; 40x0.4mm; 1% procaine; H.H
Result: Currently, healing has decreased the ulcerated area, covering much of the exposed periosteum without complications. The patient has not needed a new antibiotic treatment since the beginningof NT nor have they presented bleeding or bruises that have complicated the process.
Conclusion: NT has focused on the lesion on the scalp, interfering
fields and acupuncture points according to the related meridian.
NT could be considered a good tool for healing wounds, acute or
chronic. It could be the basis for designing deeper studies.

Correspondence to:
Mireia Serrat Bonet
E-mail: info@medicinaintegrativagirona.com

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BOOK OF ABSTRACTS | 12th European Congress of Integrative Medicine · 1st International Symposium on Integrative Health and Education

Title: Neural therapy in the treatment ofTitle: Concomitant use of natural oils andcomplex regional pain syndrome (Sudeck’s diet change may help to reduce some eyedisease, reflex sympathetic dystrophy)
symptoms in suffering from allergies
Martina Gómez Sierra1, Mireia Serrat Bonet1
1
Medicina Integrativa Girona
Objective: To assess the effectiveness of Neural Therapy in thetreatment of Complex Regional Pain Syndrome (CRPS).
Material and Methods: Neural Therapy is a technique developedin Germany that involves the injection of local anaesthetics into theskin, autonomic nerve ganglia, peripheral nerves, scars, acupuncture
points, activation points and other tissues. It is based on the theory
that any trauma, infection or surgery can damage the ANS and produce long-lasting alterations in the electrochemical or electromagnetic
functions of the tissues, interfering with the maintenance of homeostasis and the adaptation responses of the external and internal environment.
Applying a nonspecific regulatory stimulus in a specific area, it manages to restore the vegetative nervous system and the regulation of
the circulatory system.
In this case, conventional treatment is combined with Neural Therapy (NT).
We started NT with biweekly sessions.
Local therapy (papules, scar infiltration)
Segment therapy (sympathetic lumbar, femoral)
Material used: 3cc syringe; needle 20x 0.4mm, 60 x 0.4mm and 40x
0.4mm; 1% procaine and saline serum
Result: Neural Therapy has focused on the treatment of complex
regional syndrome through segment therapy and interfering fields.
In view of the result, NT could be considered a good tool for thetreatment of CRPS.
Conclusion: According to clinical guidelines, regional sympathetic
block with lidocaine does not provide any prognostic benefit in the
CRPS.
Contradictorily to the above, in our case we objectified clinical andfunctional improvement with puncture at the level of the left lumbar
sympathetic.
The papules on the scar and the stimulation of the circulation with
the intraarterial administration of procaine in the lower left limb together with the rehabilitative treatment contributed to the total recovery.

Correspondence to:
Martina Gómez Sierra
E-mail: info@medicinaintegrativagirona.com

Aleksandar Jevdic1, Dragan Jevdic2, Katarina Jevdic3, Dusan Vesovic4, Sonja Gospavic5, Drago
Bozic5
1
Dr Jevdic private practice Vrsac Serbia
2
ASTROCIT private practice Vrsac Serbia
3
Special psychiatry hospital Dr Slavoljub Bakalovic
Vrsac Serbia
4
VISAN-Sanitary Medical School of Applied Sciences Belgrade Serbia
5
Health care Center 1.Oktober Plandiste Serbia
Background
Since the eyes are exposed and sensitive, they may become an easytarget for allergens and irritants. Inflammation of the eyes is caused bychemicals release, including histamines.
Objective
The aim of this paper was to present whether the use of naturaloils and diet change may help patients to manage eye symptoms ofallergy.
Materials and methods
13 patients of both gender were included in the pilot study (5- 38,5% males, while 8 - 61,5% were females). They filled out questionnaire related to presence of allergy symptoms before treatmentcommence and two months later. Intervention consisted of diet change and natural oils use according to following pattern: I) “Relax Tonic” was applied onto whole body including face once a day; II) three
drops of “Olje 1”, dissolved in half glass of warm water, were consumed three times a day. Oils were made by “Planet zdravja” (Slovenia).
Statistical analysis was done by using SPSS v. 17.0.
Results and discussion
Results are presented before (B) and after (A) the treatment: B –15,4% of subjects reported no itchy eyes (IE), 38,5% had it occasionally, while 46,2% reported frequent IE; A - 61,5% of subjects reported
no IE, while 38,5% reported occasionally presence of IE. B – 16,7% ofsubjects reported no watery eyes (WE), 50% had it occasionally, while
33,3% had it frequently; A - 69,2% of subjects reported no WE, while
30,8% reported occasionally presence. B – 69,2% of subjects reported
under eye dark circles (UEDC), 15,4% had this symptom occasionally,and 15,4% had it frequently; A - 100% of subjects reported no UEDC.
Conclusions
This pilot study revealed that concomitant use of natural oils anddiet change may help patients to reduce allergy symptoms related toeyes (itchy eyes, watery eyes, under eye dark circles).

Correspondence to:
Aleksandar Jevdic
E-mail: jevdic@hemo.net

BOOK OF ABSTRACTS | 12th European Congress of Integrative Medicine · 1st International Symposium on Integrative Health and Education

Title: Clinical Hirudotherapy: Rheumatoid
Arthritis
Konstantin Sukhov1
1
World Hirudotherapy Organization
Material and method: Over the 2008-2019 years observed thetreatment of 14 patients with rheumatoid arthritis (6 men, 8 women,age 18 – 49 years). All patients had clinical and laboratory data confirming the activity of the disease. Prior to contacting us, 9 patients(with a disease duration of 2-5 years) received long-term treatment
with drugs, 5 patients (duration of the disease 3-5 months) did notreceive systematic treatment.
Results and Discussion: Against the background of the use of drugs
began to add sessions hirudotherapy - application medical leeches(Hirudo medicinalis), according to the schemes individually selected
for each patient (2 - 5 leeches per session). As a rule, from 5-7 sessionsof hirudotherapy, after receiving a positive clinical effect (reducing
the intensity of pain and swelling of the joints, reducing morning stiffness), the dosage of drugs was reduced, until complete withdrawal.
The main criterion for the frequency of hirudotherapy sessions was
the duration of the pain-free period in the patient. As a result, the total duration of treatment ranged from 4 to 25-30 months. In patients
who have not previously received drug therapy, the effectiveness ofhirudotherapy was higher. Of these patients, two patients-could notstand the duration of the treatment cycle and refused to continue
treatment (the duration of the pain-free period they were 1-2 weeks),
and now their condition is unknown. Nine patients have fully recovered, there are no periods of activity of the process, they live without
the use of any additional drugs, the duration of follow-up is from 1.5
to 4 years. Three patients are in the process of treatment and note a
significant improvement.
Conclusions: I believe that hirudotherapy is a powerful and effective method of treatment of RA, provided it is used correctly and reasonably.

Correspondence to:Konstantin Sukhov
E-mail: konstantinvs@yandex.ru

89

Title: Acupuncture treatment in the Postoperative period of Immediate Breast Reconstruction
Cristina Domingo Gómez1, Cristina López de San
Roman1
1Campus Docent Sant Joan de Déu
Objective:
To evaluate the efficacy of acupuncture treatment in women undergoing Immediate Breast Reconstruction (IBR), to reduce complications associated with the intervention and improve the postoperative
period.
Material and Methods:
A pilot study is carried out with four women between 25 and 57
years old undergoing IBR at the Dexeus Clinic in Barcelona. Two patients are treated with chemotherapy prior to the intervention and
one receives chemotherapy after the intervention.
The inclusion criteria are: patients with a first breast cancer withsentinel node removal, requiring mastectomy, to which IBR is performed. Patients receive acupuncture treatment the next day.
The variables are analysed: pain assessed with analogue visual scale, measurement of seroma extracted, joint mobility of the shoulder
Results:
In all patients, pain decreases after treatment.
In three patients seroma extraction was not necessary and in one
patient the amount of seroma was 10ml.
The four patients finished the treatment with a shoulder joint mobility of at least 95º.
Discussion: Patients who undergo IBR, in 80% of cases seroma is extracted twice with a volume of 50ml at a time, and in patients treatedwith Acupuncture only one patient needed a 10ml seroma extraction.
Conclusions: Acupuncture treatment helps reduce complications ofpain, seroma, and shoulder mobility, after immediate breast reconstruction (IBR).
It is considered advisable to conduct a randomised clinical trial thatcan provide more scientific evidence.

Correspondence to:
Cristina Domingo Gómez
E-mail: crispersonal.domingogomez@gmail.com

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Title: Reduction of allergic reactions inears and throat by the use of natural oils
and diet change – pilot study
Aleksandar Jevdic , Dragan Jevdic , Dusan Vesovic3, Drago Bozic4, Sonja Gospavic4, Zdravko Vulic51
Dr Jevdic Private practice Vrsac Serbia
2
ASTROCIT private practice Vrsac Serbia
3
VISAN -- Sanitary Medical School of Applied Sciences, Belgrade, Serbia
4
Health care Center “1. Oktobar”, Plandište, Serbia
5General hospital, Vrsac
1

2

Background
Itchy throat, ear congestion, itchy sinuses and/or ear canals, andpainful sinuses are common symptoms of allergy.
Objective
The aim of this paper was to present that the use of natural oils anddiet change may help patients to manage symptoms of allergy related
to throat and ears.
Materials and methods
13 patients of both gender were included in the pilot study (5- 38,5% males, while 8 - 61,5% were females). They filled out questionnaire related to presence of allergy symptoms before treatmentcommence and two months later. Intervention consisted of diet change and natural oils use according to following pattern: I) “Relax Tonic” was applied onto whole body including face once a day; II) three
drops of “Olje 1”, dissolved in half glass of warm water, were consumed three times a day. Oils were made by “Planet zdravja” (Slovenia).
Statistical analysis was done by using SPSS v. 17.0.
Results and discussion
Results are presented before (B) and after (A) the treatment: B –16,7% of subjects reported no itchy throat (IT), 58,3% had it occasionally, while 25% reported frequent IT; A – 76,9% of subjects reported
no IT, while 23,1% reported occasionally presence of IT. B – 69,2% ofsubjects reported no ear congestion (EC), 30,8% had it occasionally;A - 92,3% of subjects reported no EC, while 7,7% reported occasionallypresence. B – 53,8% of subjects reported itchy ear canals (IEC), 38,5%
had this symptom occasionally, and 7,7% had it frequently; A – 84,6%of subjects reported no IEC, while 15,4% reported it occasionally.
Conclusions
This pilot study revealed that concomitant use of natural oils anddiet change may help patients to reduce allergy symptoms such areitchy throat, ear congestion, and itchy ear canals. Further studies areneeded which will clarify positive impact of his protocol on patients
suffering from allergies.

Correspondence to:
Aleksandar Jevdic
E-mail: jevdic@hemo.net

Title: Acupuncture in the treatment ofbruxism and tinnitus
Cristina Domingo Gómez1, Josep Maria Charles
Vallcanera1
1Campus Docent Sant Joan de Déu
In the general population the prevalence of tinnitus is around 20%
according to studies. The manifestation in the form of mandibular tension such as bruxism is present in 70% of the population and significantly increases its relationship with tinnitus.
Objective
To evaluate the effectiveness of acupuncture treatment in patientsaffected by tinnitus, reducing muscle tension and improving bruxism.
Material and methods
Clinical practice: Integral integrative medicine and school of health,
together with the Master’s Degree in Energy Assessment and Acupuncture of the Docent Sant Joan de Déu Campus accredited by the
University of Barcelona.
Assessment of clinical cases in patients with tinnitus and bruxism,with treatments carried out following personalised criteria of Acupuncture according to traditional Chinese Medicine.
Results
It is observed that there is a significant decrease in tinnitus and an
improvement in decreasing muscle tension due to bruxism.
Conclusions
Acupuncture treatment significantly decreases tinnitus, improvesauditory perception and describes a general relaxation with which thequality of life in these patients is increased.

Correspondence to:
Cristina Domingo Gómez
E-mail: crispersonal.domingogomez@gmail.com

BOOK OF ABSTRACTS | 12th European Congress of Integrative Medicine · 1st International Symposium on Integrative Health and Education

Title: The use of natural oils and dietchange may help patients in reduction ofpain of different origins – our experience
Dragan Jevdic1, Aleksandar Jevdic2, Katarina Jevdic3, Dusan Vesovic4, Drago Bozic5, Sonja Gospavic5
1
ASTROCIT private practice, Vrsac, Serbia
2”Dr Jevdic” private practice, Vrsac, Serbia
3
Psychiatry hospital Dr Slavoljub Bakalovic Vrsac
Serbia4
VISAN -- Sanitary Medical School of Applied Sciences, Belgrade, Serbia
5
Health care Center “1. Oktobar”, Plandište, Serbia
Background
Chronic pain is usually present in older population. Common chronic pain complaints include headache, low back pain, cancer pain, arthritis pain, neurogenic pain, psychogenic pain etc.
Objective
The aim of this paper was to present the results of intervention consisting of diet change and natural oils use in patients with chronic pain.
Materials and methods
37 patients of both gender were included in the study (7 - 18,9%
males, and 30 - 81,1% females). Mean age was 60,7+-11,9yrs. They
filled out questionnaire related to presence and origin of pain before
treatment commence and two months later. Intervention consistedof natural oils use and diet change according to following protocol: I)“Relax Tonic” was applied onto whole body including face; II) when
the skin has become dry, person took a shower and applied “Olje 10”
onto wet skin of whole body and face. This procedure was repeatedonce daily for the period of study. Oils were made by “Planet zdravja”(Slovenia). Statistical analysis was done by using SPSS v. 17.0.
Results and discussion
68,6% of subjects examined took pain killers, while only 31,4% did
not. 71% of examined persons took drugs because of musculoskeletal
disorders. After the treatment, 3,3% of subject “did not have attitude
regarding treatment”, 60% of them reported that they “believe thatthe treatment was successful”, while 37,7% reported that “do not believe that the treatment was successful”. 63,3% of subjects reported
that “protocol is easy to use”, while 36,7% reported it was not.
Conclusions
Vast majority of tested subjects reported that they were satisfied
with effects of protocol and reported that the protocol was easy foruse. Therefore, this study showed promising results that the use ofnatural oils and diet change may be significant tool in medical practice
to reduce pain in suffering subjects.

Correspondence to:
Dragan Jevdic
E-mail: jevdicdragan@gmail.com

91

Title: The use of natural oils and dietchange can improve quality of life in people suffering from allergy – results frompilot study
Dragan Jevdic1, Aleksandar Jevdic2, Dusan Vesovic3, Drago Bozic4, Sonja Gospavic4, Zdravko Vulic5
1
ASTROCIT private practice, Vrsac, Serbia
2”Dr Jevdic” private practice, Vrsac, Serbia
3
VISAN -- Sanitary Medical School of Applied Sciences, Belgrade, Serbia
4
Health care Center “1. Oktobar”, Plandište,, Serbia
5General hospital, Vrsac
Background
Allergy symptoms may significantly affect subjects’ quality of life
(Qol).
Objective
The aim of this paper was to present whether the use of natural oils
and diet change may help patients to improve QoL.
Materials and methods
13 patients of both gender were included in the pilot study (5 38,5% males, while 8 - 61,5% were females). They filled out questionnaire related to presence of allergy symptoms before treatment commence and two months later. Intervention consisted of diet change
and natural oils use according to following pattern: I) “Relax Tonic” wasapplied onto whole body including face once a day; II) three drops of“Olje 1”, dissolved in half glass of warm water, were consumed threetimes a day. Oils were made by “Planet zdravja” (Slovenia). Statisticalanalysis was done by using SPSS v. 17.0.
Results and discussion
Results are presented before vs. after the treatment as mean value+- standard deviation. Physical fitness score: 51,08+-11,4 vs. 61,23+6,0 (p=0,013); psychological status score: 54,8+-12,0 vs. 67,4+-10,2(p=0,004); attitude in relation to environment score: 69,5+-14,4
vs. 75,6+-15,0 (p=0,013). Improvement in social relations was alsoachieved, but was no statistically relevant – 69,8+-15,9 vs. 72,1+-15,6(p=0,177).
Conclusions
This pilot study revealed that the concomitant use of natural oils
and diet change may help patients suffering from allergies to improve
quality of life. Further (placebo-control, double-blinded, longer duration) studies are needed to better clarify this issue and to reveal possible mode of action of this protocol.

Correspondence to:
Dragan Jevdic
E-mail: jevdicdragan@gmail.com

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Title: An influence of natural oils and dietchange on the use of antihistamines anddecongestants in people suffering from allergy – results from pilot study
Dragan Jevdic1, Aleksandar Jevdic2, Dusan Vesovic3, Drago Bozic4, Sonja Gospavic4, Zdravko Vulic5
1
ASTROCIT private practice, Vrsac, Serbia
2”Dr Jevdic” private practice, Vrsac, Serbia
3
VISAN -- Sanitary Medical School of Applied Sciences, Belgrade, Serbia
4
Health care Center “1. Oktobar”, Plandište, Serbia
5General hospital, Vrsac
Background
Antihistamines and corticosteroids are drugs in treating allergy.
Objective
The aim of this paper was to present that the use of natural oils anddiet change may help patients to reduce the use of drugs in allergy.
Materials and methods
13 patients of both gender were included in the pilot study (5 38,5% males, while 8 - 61,5% were females). They filled out questionnaire related to presence of allergy symptoms before treatment commence and two months later. Intervention consisted of diet change
and natural oils use according to following pattern: I) “Relax Tonic”
was applied onto whole body including face once a day; II) three dropsof “Olje 1”, dissolved in half glass of warm water, three times a day.
Oils were made by “Planet zdravja” (Slovenia). Statistical analysis wasdone by using SPSS v. 17.0.
Results and discussion
Results are presented before (B) and after (A) the treatment: B –23,1% of subjects reported no use of nasal sprays (NS), 30,8% tookthem occasionally, while 46,2% reported frequent use of NS; A –69,2% of subjects reported no use of NS, while 30,8% reported occasionally use. B – 76,9% of subjects reported no use of eye drops (ED),and 23,1% took them occasionally; A – 100% subjects reported nouse of ED. B – 23,1% subjects reported the use of antihistamines (AH),
23,1% used them occasionally, and 53,8% reported frequent use; A– 76,9% subjects reported no use of AH, while 23,1% reported occasionally use. B – 53,8% of subjects reported the use of corticosteroids(C), 23,1% used them occasionally, and 23,1% used them frequently;
A – 100% subjects reported no use C.
Conclusions
This pilot study came up with results that the use of natural oils anddiet change may help patients to reduce the use of most common
allergy drugs.

Correspondence to:
Dragan Jevdic
E-mail: jevdicdragan@gmail.com

Title: Describe whether Tai Chi (TC) is effective in preventing falls in older people
María del Carmen Dorta Francisco1, ManuelRomero Hernandez2
1
Médico especialista en Aparato Digestivo. Monitora Nacional Tai Chi estilo Hun Yuan
2
Doctor Economia.Universidad Las Palmas deGran Canaria
Objectives
Describe whether Tai Chi (TC) is effective in preventing falls in older
people.
Material and methods
A review of the literature in PubMed of the last 23 years (19962019) has been carried out. Keyword “Tai Chi and prevention falls.”
Discarded studies in which the practice of TC was analysed along withother sports disciplines (Yoga); discarded comparative studies between TC and other therapies (Physiotherapy, Otago)
Analysis
Various epidemiological studies (1 community intervention trial,
1 clinical trial, 1 descriptive study, 7 meta-analyses, 6 systematic reviews, 27 randomised)
Result and Discussion
Falls in the elderly are a global public health problem. The incidenceof falls increases with age. One in 3 people over 65 falls a year, and it
reaches 50% in people over 80 years old. 5-20% of those who fall haveserious injuries.
TC is an effective activity in the improvement of balance, in the prevention of falls, and in injuries produced after falls, in the elderly. Not
all studies show that TC is effective in reducing falls. When the efficacy
has not been demonstrated, it is because the program has not beenlong enough, or the sample size was small.
Conclusion
Results show that TC is suitable for older people because it is aerobic, of moderate intensity, consisting of rhythmic, continuous andslight impact movements. It is an exercise that improves leg strength,balance, coordination, and decreased fear of falling.
Programs should be implemented in the community, in which Tai
Chi practice is adapted to the needs and abilities of older adults, sothat it has a positive impact on their health.

Correspondence to:
María del Carmen Dorta Francisco
E-mail: taichi.mari@gmail.com

BOOK OF ABSTRACTS | 12th European Congress of Integrative Medicine · 1st International Symposium on Integrative Health and Education

Title: Correlating Traditional Chinese Medicine Asthma Phenotypes to Objective
Conventional Medicine Asthma Evaluation
Han Hui Cheong , Chun Huat Teo , Yun Shan Lam ,Tze Chao Lim2, Benjamin Chueng Kiat Lau3, Oon
Hoe Teoh4
1
Department of Pharmacy, KK Women’s and Children’s Hospital
2
Singapore Thong Chai Medical Institution
3
Department of Pharmacy, National University ofSingapore
4
Paediatrics Medicine Respiratory Services, KK
Women’s and Children’s Hospital1

2

2

Objectives: To determine the distribution of childhood asthma phenotypes according to Traditional Chinese Medicine (TCM) philosophy
and to correlate these to conventional medicine (CM) asthma evaluation methods.
Material and method: An observational, cross-sectional study was
conducted at a tertiary paediatric hospital over 6 months. Patients
aged 6 to 16 years attending respiratory outpatient consultation withspirometry done were recruited. Demographics, medical history andspirometry results were collected. Pulse characteristics, tongue appearance and clinical symptoms were assessed by TCM practitioners
for classification into TCM phenotypes.
Analysis: Descriptive statistics and correlation analyses were performed.
Results: Ninety two patients were enrolled with mean age of 10
years old and 67% (62) were males. Main TCM asthma phenotypes
identified were Lung-Spleen Chi Deficiency (LSCD) at 73.9%, Lung-Kidney Yin Deficiency (LKYID) at 20.7% and Spleen-Kidney Yang Deficiency (SKYAD) at 5.4%. The mean pre-bronchodilator forced expiratory
volume at 1 minute (FEV1) for SKYAD is 77.8% of predicted, as compared to 84.2% and 89.5% respectively for LSCD and LKYID. Allergic
rhinitis and eczema were reported by 90.2% and 41.3% of all subjects
respectively. Eczema was found to be associated with non-LSCD phenotypes with an odds ratio of 3.26 (p-value 0.017).
Discussion: LSCD is the majority and SKYAD the minority of TCM
phenotypes observed at the outpatient clinics. In TCM philosophy,
SKYAD phenotypes have the weakest body constitution as a result ofchronic deficiencies, and in our study SKYAD subjects have the lowest
lung function (FEV1). LSCD phenotype has the lowest association witheczema.
Conclusions:Differences in lung function and allergic co-morbidities can be observed in different TCM asthma phenotypes, suggesting corresponding physiological and clinical relevance of TCM asthma phenotypes
when evaluated by objective CM methods. This suggests that further
research into the added value of integrated asthma management using CM and TCM principles is clinically feasible.

Correspondence to:Han Hui Cheong
E-mail: cheonghanhui@yahoo.com

93

Title: Danggui-Shaoyao-San for Dementia:
Systematic Review
Yunna Kim1, Seung-Hun Cho1
1
Department of Korean Neuropsychiatry, Kyung
Hee University, Seoul, Korea
Objectives: Although memory loss and other symptoms of dementia pose tremendous burdens to patients and societies, there iscurrently no cure for dementia. We conducted a systematic review
and meta-analysis about the anti-dementia effects of Danggui-Shaoyao-San (DSS), derived from natural resources.
Materials and methods: We searched randomized controlled trials
from inception through March 2019. We searched Pubmed, EMBASE,
Korean databases (Research Information Service System (RISS) and
Oriental Medicine Advanced Searching Integrated System (OASIS)),
Chinese databases (China Knowledge Resource Integrated Database(CNKI) and Wanfang Database) and Japanese databases (Cinii and
J-STAGE). Studies were included if they were a randomized controlled
trial (RCT); investigated the efficacy of DSS or its modified form; andincluded participants with dementia. Use of DSS with other treatment(e.g., acupuncture, antidementia drugs, etc.) was included.
Analysis: Items of each trial were evaluated by two independent reviewers. Data were pooled by using random-effect models.
Results: 482 studies were identified, and five eligible studies for
Alzheimer’s disease (AD) and four studies for vascular dementia (VD)
were included in the final analysis, representing a total of 567 participants. As for AD, pooled results of the Mini-Mental State Examination(MMSE)(MD 4.60; 95% CI 4.29, 4.91) and activities of daily living (ADL)(MD 11.40; 95% CI 10.94, 11.86) favored DSS. DSS had synergistic effect with acupuncture over acupuncture alone in MMSE(MD 1.69;
95% CI 1.05, 2.34), Hasegawa Dementia Scale (HDS)(MD 0.62; 95%
CI -0.20, 1.44), and ADL(MD 2.38; 95% CI 1.92, 2.85). In VD, pooled
results showed a significant difference in the score of dementia scales
such as MMSE and HDS compared with nootropic drugs. DSS significantly reduced symptoms(OR, 5.02; 95% CI 2.76-9.11) in patients with
VD.
Conclusions: These estimates suggest that DSS provides clinicallyimportant reductions in symptoms of AD and VD and can be a promising anti-dementia drug candidate.

Correspondence to:
Yunna Kim
E-mail: yunna.anna.kim@khu.ac.kr

94

BOOK OF ABSTRACTS | 12th European Congress of Integrative Medicine · 1st International Symposium on Integrative Health and Education

Title: The presence of food intolerance,
bacteria, and toxins in subjects with various diseases revealed by bioresonanceTatjana Misic1, Dusan Vesovic2, Dragan Jevdic Jevdic3
1
Military Medical Academy, Belgrade, 11.000, Serbia
2
VISAN -- Sanitary Medical School of Applied Sciences, Belgrade, 11.000, Serbia
3
Private practice “Astrocit”, Vrsac, 26.300, Serbia
Background
Along with conventional approach in treatment of subjects withchronic non-communicable diseases (CnCD), the use of bioresonancemay be very useful.
Objective
The aim of the paper was to present the presence of food intolerance, bacteria, and toxins in subjects suffering from CnCD.
Materials and methods
67 patients of both gender were included in the study (28 – 41,8%
males, and 39 – 58,2% females). Mean age was 41,8+-7,9yrs. They
filled out questionnaire related to presence of diseases in accordance
to International Classification of Diseases 10 (ICD-10).
Afterward they were tested at bioresonance therapy apparatus
which was made in Germany. Statistical analysis was done by using
SPSS v. 17.0.
Results and discussion
7 subjects (10,4%) were diagnosed with neoplasm, diseases ofblood and blood forming organs had 5 subjects (7,5%) and the same
number of subjects suffered from mental and behavioural diseases;
endocrine, nutritional, and metabolic diseases were diagnosed in 3
subjects (4,5%), diseases of nervous system were present in 4 subjects(6%), 8 (11,9%) subjects suffered from eye diseases, while 14 subjects(20,9%) had ear problems. Diseases of circulatory system were foundin 14 subjects (20,9%), diseases of respiratory system were found in 19
subjects (28,4%), while 28 subjects (41,8%) had problems with digestive system. 31 subjects (46,3%) reported diseases of skin, 21 of them
(31,3%) reported musculoskeletal diseases, while 20 subjects had
problems with genitourinary system. Bicom testing revealed following
results: mercury was present in 97,7% subjects, oxyuris, aspergillus,
and aflatoxin in 93%, formaldehyde in 88,4%, Helicobacter pylori in
88,4%, sugar intolerance in 83,7%, thimerosal in 79,1%, milk intolerance in 76,7%, and gluten intolerance in 74,4% of tested subjects.
Conclusions
Very high prevalence of toxins, fungi, bacteria, and food intolerance
is present in patients suffering from CnCD. By using bioresonancetreatment those health burdens may be diminished.

Correspondence to:
Tatjana Misic
E-mail: tanja.misic@yahoo.com

Title: Prevalence of bacteria, toxins, andfood intolerance in subjects diagnosed
with digestive system ailments revealedby bioresonanceTatjana Misic1, Dusan Vesovic2, Dragan Jevdic Jevdic3
1
Military Medical Academy, Belgrade, 11.000, Serbia
2
VISAN -- Sanitary Medical School of Applied Sciences, Belgrade, 11.000, Serbia
3
Private practice “Astrocit”, Vrsac, 26.300, Serbia
Background
Bioresonance is very useful approach in defining health burdens inpeople suffering from various diseases.
Objective
The aim of the paper was to present the presence of various healthburdens in subjects diagnosed with digestive system ailments (DSA).
Materials and methods
130 patients of both gender were included in the study (48 – 36,9%
males, and 82 – 63,1% females). Mean age was 42,6+-8,9yrs. They
filled out questionnaire related to presence of diseases in accordance
to International Classification of Diseases 10 (ICD-10).
Afterward they were tested at bioresonance therapy apparatus
which was made in Germany.Statistical analysis was done by using
SPSS v. 17.0.
Results and discussion
Of 130 subjects enrolled into study, 61 (46,8%) were diagnosed
with DSA. Bicom testing revealed presence of following health burdens in these subjects: mercury was present in 27 (96,4%) subjects,
gluten intolerance, Helicobacter pylori, Aspergillus, aflatoxin, and lead
were found in 26 (92,9%) tested subjects. Candida and formaldehyde
were found in 25 (89,3%) examinees. Presence of oxyuris, aluminum,and vitamin D deficiency were revealed in 24 subjects (85,7%), while
milk and pork meat intolerance, ascaris, and Staphylococcus were
found in 23 (82,5%) examinees. Sugar intolerance was present in 22(78,6%) subjects.
Conclusions
The most prevalent findings in examinees diagnosed with DSA were
mercury intoxication, gluten intolerance, presence of Helicobacter pylori, Aspergilus, aflatoxin, lead intoxication, followed by presence ofCandida and formaledhyde. Bioresonace may be useful in finding out
those health burdens and diminishing them.

Correspondence to:
Tatjana Misic
E-mail: tanja.misic@yahoo.com

BOOK OF ABSTRACTS | 12th European Congress of Integrative Medicine · 1st International Symposium on Integrative Health and Education

95

Title: The most prevalent health burdens
Title: Natural oils and diet change may
revealed by bioresonance in patients sufhelp people suffering from allergy – refering from circulatory diseases - our expe- sults from pilot study
rienceTatjana Misic , Dusan Vesovic , Dragan Jevdic Jevdic3
1
Military Medical Academy, Belgrade, 11.000, Serbia
2
VISAN -- Sanitary Medical School of Applied Sciences, Belgrade, 11.000, Serbia
3
Private practice “Astrocit”, Vrsac, 26.300, Serbia
1

2Background
Circulatory diseases are one of the most prevalent death causes indeveloped countries worldwide today.
Objective
The aim of the paper was to present what health burdens we foundin people diagnosed with circulatory diseases (CD).
Materials and methods
67 patients of both gender were included in the study (28 – 41,8%
males, and 39 – 58,2% females). Mean age was 41,8+-7,9yrs. They filled out questionnaire related to presence of diseases in accordance
to International Classification of Diseases 10 (ICD-10).
Afterward they were tested at bioresonance therapy apparatus
which was made in Germany.Statistical analysis was done by using
SPSS v. 17.0.
Results and discussion
14 subjects (20,9%) were diagnosed with CD. Bioresonance revealed presence of Candida, aflatoxin, and mercury in all patients(100%) diagnosed with circulatory diseases. Bioresonance found out
presence of Asperillus and lead in 92,9% of tested subjects with CD.
Milk intolerance, presence of Helicobacter pylori, Staphiloccocus, andOxyuris were revealed in 85,7% of subjects. 78,6% of subjects diagnosed with CD had Streptococcus, Ascaris, and vitamin D deficiency.
71,4% subjects were intolerant to gluten and pork meat, were chromium deficient, and had formaldehyde in body. 64,3% of those withCD had sugar intolerance and were selen deficient. 57,1% of subjects
showed presence of EBV, Candida, Aluminum, thimerosal, and werezinc deficient. All other health burdens were present in less than 50%
of subjects.
Conclusions
Bioresonance may be very useful tool to reveal presence of healthburdens in subjects diagnosed with circulatory diseases and may be
used concomitant with classical therapy with an aim to clean up bodyfrom toxins, bacteria, and fungi. Also, bioresonance may reveal mineral/vitamins deficiencies which can be solved by appropriate dietchange and supplementation. This, in turn, will help and acceleratehealing process

Correspondence to:
Tatjana Misic
E-mail: tanja.misic@yahoo.com

Dusan Vesovic1, Dragan Jevdic2, Drago Bozic3, Sonja Gospavic3, Zdravko Vulic4, Aleksndar Jevdic5
1
VISAN -- Sanitary Medical School of Applied Sciences, Belgrade, Serbia
2
ASTROCIT, private practice, Vrsac, Serbia
3
Health care Center “1. Oktobar”, Plandiste, Serbia
4General hospital, Vrsac, Serbia
5”Dr Jevdic” private practice, Vrsac, Serbia
Background
Shortness of breath, wheezing, and coughing are most common
symptoms of allergy.
Objective
The aim of this paper was to present that the use of natural oils anddiet change may help patients to manage some symptoms of allergy.
Materials and methods
13 patients of both gender were included in the pilot study (5 38,5% males, while 8 - 61,5% were females). They filled out questionnaire related to presence of allergy symptoms before treatment commence and two months later. Intervention consisted of diet change
and natural oils use according to following pattern: I) one natural oil
was applied onto whole body including face once a day; II) three dropsof other natural oil, dissolved in half glass of warm water, were consumed three times a day. Oils were made by firm from Slovenia. Statistical analysis was done by using SPSS v. 17.0.
Results and discussion
Results are presented before (B) and after (A) the treatment: B –30,8% of subjects reported no shortness of breath (SoB), 53,8% had
it occasionally, while 15,4% reported frequent SoB; A – 76,9% of subjects reported no SoB, while 23,1% reported occasionally presence ofSoB. B – 30,8% of subjects reported no wheezing (W), 53,8% had it occasionally, while 15,4% had it frequently; A – 84,6% of subjects reported no SoB, while 15,4% reported occasionally presence. B – 23,1% ofsubjects reported coughing (C), 38,5% had this symptom occasionally,and 38,5% had it frequently; A – 76,9% of subjects reported no SoB,
while 23,1% reported it occasionally.
Conclusions
This pilot study revealed that concomitant use of natural oils anddiet change may help patients to reduce allergy symptoms such areshortness of breath, wheezing, and coughing. Further studies withbigger sample size are needed to put more light on the effects of thisprotocol on allergy symptoms.

Correspondence to:Dusan Vesovic
E-mail: vesovic@rocketmail.com

96

BOOK OF ABSTRACTS | 12th European Congress of Integrative Medicine · 1st International Symposium on Integrative Health and Education

Title: Effects of concomitant use of naturaloils and diet change on some nasal symptoms in people suffering from allergies –pilot study

Title: Hashimoto thyroiditis consensus
document of the Spanish Society of Healthand Integrative Medicine SESMI: An integrative vision

Dusan Vesovic1, Dragan Jevdic2, Drago Bozic3, Sonja Gospavic3, Zdravko Vulic4, Aleksndar Jevdic5
1
VISAN -- Sanitary Medical School of Applied Sciences, Belgrade, Serbia
2
ASTROCIT, private practice, Vrsac, Serbia
3
Health care Center “1. Oktobar”, Plandiste, Serbia
4General hospital, Vrsac, Serbia
5”Dr Jevdic” private practice, Vrsac, Serbia

Isabel García Martín1, Sergio Abanades León1
1
ISIC (Instituto de Salud Integrativa Y Consciente)

Background
Allergic conditions are one of the most common health issues affecting children and adults worldwide.
Objective
The aim of this paper was to present whether the use of naturaloils and diet change may help patients to manage nasal symptomsof allergy.
Materials and methods
13 patients of both gender were included in the pilot study (5 38,5% males, while 8 - 61,5% were females). They filled out questionnaire related to presence of allergy symptoms before treatment commence and two months later. Intervention consisted of diet change
and natural oils use according to following pattern: I) one natural oil
was applied onto whole body including face once a day; II) three dropsof other natural oil, dissolved in half glass of warm water, were consumed three times a day. Oils were made by firm from Slovenia. Statistical analysis was done by using SPSS v. 17.0.
Results and discussion
Results are presented before (B) and after (A) the treatment: B 23,1% of subjects reported runny nose (RN) occasionally, while 76,9%
reported frequent RN; A - 61,5% of subjects reported no RN, while
38,5% reported occasionally presence of RN. B - 7,7% of subjects reported no itchy nose (IN), 38,5% had it occasionally, and 53,8% had it
frequently; A - 69,2% of subjects reported no IN, while 30,8% reported
occasionally presence. B - 7,7% of subjects reported no nasal congestion (NC), 23,1% had this symptom occasionally, and 69,2% had it frequently; A - 76,9% of subjects reported no NC, while 23,1% reported
occasionally presence. Regarding sneezing, the same proportion was
revealed as for IN.
Conclusions
This pilot study revealed that concomitant use of natural oils anddiet change may help patients to reduce allergy symptoms related tonose (runny nose, itchy nose, congestion, and sneezing).

Correspondence to:Dusan Vesovic
E-mail: vesovic@rocketmail.com

Objectives
Conventional treatment of autoimmune thyroiditis or Hashimoto’s
disease (HD) is based on hormonal replacement and periodic dosemonitoring and adjustment. However, it is occasionally unable to control the symptoms and does not address its possible causes. This paper intends to describe the scientific evidence about the causes andpromoters of the disease and the possible prevention and treatment
strategies.
Material and method
An exhaustive search of scientific literature has been carried out,
updated to September 2018 (83 keywords in Pubmed, EMBASE, andCochrane Library, 2 authors and separate review by 2 external reviewers). A first screening of references was made based on the title
and summary of each of them and subsequently the full-text document of those shortlisted studies for the final selection was recovered.
Results
A total of 318 original articles were selected for final review. According to the information found, there would be 3 main factors in
the pathogenesis of HD: a genetically altered immune system; antigens capable of reacting against the immune system associated withmucous membranes, and a leaky intestinal mucosa that facilitates
its entry into the systemic circulation. This includes robust scientificevidence that relates the disease to the following factors: intestinal
permeability and/or dysbiosis, infectious factors, heavy metal andother toxic poisoning, vitamin D deficiency, gluten, excess iodine or
low selenium/iodine ratio, hormonal factors and emotional factors.
In addition, there is preliminary evidence that the correction of thesealterations could facilitate the improvement of thyroid function andautoimmunity.
Discussion
The evolutionary control and treatment of HD should include amultidisciplinary/integrative approach that can influence the different
factors related to its pathogenesis and its multisystemic consequences.
Correspondence to:
Isabel García Martín
E-mail: i.garcia@isic-bcn.com

BOOK OF ABSTRACTS | 12th European Congress of Integrative Medicine · 1st International Symposium on Integrative Health and Education

Title: Naltrexone at low dose for the treatment of chronic pain
Natàlia Subirats Duran1
1Institut de Salut Integrativa i Conscient
OBJECTIVES: Low dose naltrexone is an opioid antagonist that has
been shown to reduce the severity of symptoms in cases of fibromyalgia, multiple sclerosis, Crohn’s disease and complex regional pain syndrome. In small doses, naltrexone may have analgesic and anti-inflammatory effects. It acts on the microglia through an antagonistic action
with the non-opioid receptors called Toll-Like receptor4 and also
temporarily blocks the opioid receptors producing a self-regulation ofthem. The dose of naltrexone is variable being between 0.5mg-4.5mg.
MATERIAL AND METHODS: Description of a clinical case and reviewof the literature.
ANALYSIS: 66-year-old woman, diagnosed with Sd Sjogren 30 yearsof evolution. She presents tear and oral dryness, frontal alopecia andgeneralised pain with an EVA 8/10.
RESULTS: We start Naltrexone at a dose of 0.5mg/day, in 7 days there is an improvement in EVA from 8/10 to 4/10, after 15 days they report EVA 3/10 and a feeling of agility. Pending control analysis results.
CONCLUSIONS: Naltrexone at low doses may be an alternative tothe treatment of chronic pain due to its anti-inflammatory and analgesic effects, having studies with significant results in diseases thatencompasses the central sensitivity syndrome. The use of the drugin this case has decreased pain by 5 points on the VAS scale in only
15 days.
DISCUSSION: Naltrexone at low doses is a drug to consider in autoimmune diseases, which modulates inflammation and acts as
an analgesic by different pathophysiological mechanisms. The side
effects described are not considered serious. Although several studies
have already been published, their size is small. A phase 3 study with alarger size for FDA-approved Crohn’s disease has now been approved.

Correspondence to:
Natàlia Subirats DuranE-mail: nataliasubirats@gmail.com

97

Title: Chronic urticaria and histaminergic
angioedema
Natàlia Subirats Duran1
1Institut de Salut Integrativa i Conscient
OBJECTIVES: Histamine angioedema (HA) is often mediated by histamine or bradykinin. Recurrent HA ends up being diagnosed as chronic urticaria (CU), although there is no presence of superficial hives.
CU is a benign disease, and autoimmune in 40% of cases. It is important to determine the origin of the symptoms to guide the treatment,
which is composed of antihistamines, corticosteroids and epinephrine. MATERIAL AND METHODS: Description of a clinical case and review of the literature. ANALYSIS: A 46-year-old male, with a historyof pulmonary tuberculosis, Gilbert’s disease and changes in bowel
movements. In follow-up by the hospital allergology service. Negative complementary tests except positive allergy for dogs and cats. The
patient has HA and CU of 15 years of evolution, episodes of angioedema every month and a half that last about 24 hours, and generalised
urticaria that occurs in weekly outbreaks. Is treated with levocetirizine
every 48h. RESULTS: In initial analysis: leukocytes 5200, eosinophils
6.1% and lymphocytes 40.2%, IgE 916 kUI/L, together with DAO 6.8
kU/L, IgG EBV VCA 87 U.arb/ml and IgG EBV EBNA 7.20 U.arb/ml. Tested positive for diaentamoeba fragilis in the intestinal dysbiosis test.
We performed treatment with paramomycin 500mg/8h for 7 days,
glutamine, megaquercetin and low histamine diet. In a control visit
after 2 months, the patient presented with disappearance of hives,
reduction of the intensity and frequency of episodes of angioedema
and antihistamine medication. Improvement of digestive symptoms.
DISCUSSION: Chronic urticaria of more than 1 year of evolution has
a prevalence of 11-15% of the population, in addition to a serious
impact on the patient’s quality of life. In CU the analysis of parasites
in faeces along with serology for the Epstein Barr virus (EBV) is important, because coinfections can often be the cause of autoimmune
diseases.

Correspondence to:
Natàlia Subirats DuranE-mail: nataliasubirats@gmail.com

98

BOOK OF ABSTRACTS | 12th European Congress of Integrative Medicine · 1st International Symposium on Integrative Health and Education

Title: Osteopathic treatment in Chronic
Musculoskeletal Pain Diseases – Results ofan Observational Pilot Study
Gabriele Rotter1, Miriam Ortiz1, Michael Teut1,
Sylvia Binting1, Benno Brinkhaus1
1Institute for Social Medicine, Epidemiology and
Health Economics, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität
Berlin, Humboldt-Universität zu Berlin, and Berlin
Institute of Health, Germany
Objectives
Patients with chronic musculoskeletal pain often use osteopathic
medicine (OM). However the evi-dence regarding effectiveness andsafety is unclear. We investigated the effects and safety of OM in patients with chronic musculoskeletal pain.
Materials and Methods
The observational pilot study included patients suffering fromchronic neck pain (cNP) (n=10), chron-ic low back pain (cLBP) (n=10),
chronic shoulder pain (cSP) (n=10), or chronic knee pain (cKP) (n=10).
All patients received six OM sessions every 3 to 4 weeks during 26
weeks in addition to rou-tine care in an university outpatient clinic.
Outcome parameters were among others the average pain intensity
on visual analogue scale (VAS, 0-100mm, 0=no pain, 100=worst imaginable pain), the SF-12 health related quality of life and safety at baseline, after 26 and 52 weeks. The statistical analysis was descriptive,
the analysis of the outcomes was explorative in comparison pre-post.
Results
We recruited altogether 40 patients (female (n=29), mean age
47.7±8.3 years, at baseline: mean VAS pain 59.4mm [95% confidence
interval, 55.4;63.4], mean SF-12 physical component 39.2 [36.7;41.8],
mean SF-12 mental component 48.6 [45.7;51.5]). After 26 weeks improved were the mean pain intensity on VAS (-33.1mm [-40.5,-25.7];
p<.001) and the SF-12 physical component (6.9 [4.2;9.5], p<0.001),
but not the SF-12 mental component (-0.02 [-3.1;3.0], p=0.990) in
the whole population. We observed the best pain improvement in
cKP (mean -38.1mm [-49.1;-27.0], p<.001), the lowest in cLBP (mean-28.2mm [-47.9;-8.4], p=0.006). The SF-12 physical component
showed the best improvement in cSP (mean 9.1 [4.9;13.3], p=0.001),
lowest in cLBP (mean 5.4 [-0.1;10.9], p=0.054). The improvements
persisted until the follow up at week 52. No adverse events wereob-served.
Conclusions
Study results suggest that OM with six sessions in addition to routine care might be beneficial and safe in chronic musculoskeletal pain
diseases. These results should be verified in randomized clini-cal trials.

Correspondence to:Gabriele Rotter
E-mail: gabriele.rotter@charite.de

Title: Levels of vitamin D3 in blood andtear of athletes practicing indoor and outdoor activities and evaluation of effectiveness of vitamin D3 eye drops
Renato Leça1, Rafaela Vicentim1, Ana Luiza Hofling de Lima2, Carla Scorza2, Fúlvio Scorza2, Fernando Fonseca1
1Faculdade de Medicina do ABC (Brazil)
2Universidade Federal de São Paulo
Goal
To compare vitamin D3 levels in tear and blood of healthy young
adults practicing physical activity and to evaluate the effects of supplementation with vitamin D3 eye drops
Method36 volunteers (19a 27years) separated into two groups: indoor activities (sun exposure <3h / week) and outdoor (> 7h / week). VitaminD3 levels in blood (3 ml of venous blood) and tear (Schirmer tapes)
were evaluated. Both the tear and the blood passed through the electrochemiluminescence method, to evaluate the levels of the metabolite 25 (OH) vitamin D3. After this, vitamin D3 eye drops were used toevaluate possible changes at these levels.
Result
The mean plasma vitamin D3 level of the indoor group was 25.01
ng / ml, while the mean plasma vitamin D3 level of the outdoor groupwas 35.55 ng / ml (p <0.05). In all 36 participants, vitamin D3 levelsin the tear were higher than 100 ng / ml (the maximum limit of thesystem used), well above the plasma levels in the two groups of participants (p <0.01). In 6 of these randomly chosen subjects, the prepared vitamin D3 eye drops were used, in which each drop contained
5000 IU, and 1 drop was instilled in each eye 2 times a day for 3 weeks
to evaluate serum levels. An average increase in the plasma level of
25.18%, ranging from 9.2 to 42.8%.
Conclusion
Lacrimal levels of vitamin D3 were significantly higher than plasma
levels in both internal and external physical activities (p <0.01). The
eyedrops were effective and increased serum D3 levels by 25.18%,
with only 3 weeks of use, proving the usefulness of the conjunctival
pathway for vit D3 absorption. Both results are unprecedented in theworld literature.

Correspondence to:Renato Leça
E-mail: renatoleca@terra.com.br

BOOK OF ABSTRACTS | 12th European Congress of Integrative Medicine · 1st International Symposium on Integrative Health and Education

Title: Effects of vegan versus meat-richdiet on markers of inflammation – a randomized, controlled trial
Lederer Ann-Kathrin1, Maul-Pavicic Andrea2, Luciana Hannibal3, Müller Alexander1, Gründemann
Carsten1, Huber Roman1
1
Center for Complementary Medicine, Institutefor Infection Prevention and Hospital Epidemiology, Medical Center – University of Freiburg
2
Department of Rheumatology and Clinical Immunology and Center for Chronic Immunodeficiency,
Medical Center – University of Freiburg
3
Laboratory of Clinical Biochemistry and Metabolism, Department for Pediatrics, Medical Center University of Freiburg
Background:
Vegan diet has improved inflammatory activity in patients withrheumatoid arthritis (RA) in several small controlled trials. The underlying mechanism remains widely unclear. We investigated the effect ofa vegan diet (VD) in comparison to meat-rich diet (MD) on markers ofinflammation, which have been shown to be relevant in patients with
RA, in healthy volunteers.
Methods:
53 healthy, omnivore subjects were randomized to a controlled VD(n = 26) or MD (n = 27) for 4 weeks following a pre-treatment phase of
one week of controlled mixed diet. Primary parameters were sialylation of immunoglobulins, percentage of regulatory t-cells and level ofinterleukin 10 (IL10). Usual care immune parameters used in patientswith RA and amino acid serum levels were examined as secondary
parameters.
Results:
In the VD group total leukocytes, neutrophils, monocytes and platelet counts decreased and were after four weeks significantly lower
compared to the MD group (leukocytes p = 0.001, neutrophils p =0.001, monocytes p = 0.010, platelets p = 0.004). Leukocytes, neutrophils, monocytes and platelets correlated with each other and also
correlated with serum levels of branched chain amino acids, whichwere significantly lower in the VD compared to the MD group. The
primary parameters did not differ between the groups; BMI remained
stable in the two groups.
Conclusion:
Four weeks VD affected the number of neutrophils, monocytes andplatelets but not the number or function of lymphocytes. The relation
with branched chain amino acids suggests a mode of action via themTOR signaling pathway.

Correspondence to:Lederer Ann-Kathrin
E-mail: ann-kathrin.lederer@uniklinik-freiburg.de

99

Title: Effectiveness of Standard of Careversus Its Combination with Reflexology,
and Sham Reflexology on Preoperative
Anxiety in Patients Undergoing Laparoscopic Cholecystectomy: A Randomized
Controlled Trial. Preliminary Results
Attias Samuel1
1
Bnai Zion Medical Center
Background: Preoperative anxiety is associated with a negative
surgery experience and increased morbidity with implications for public health. Several studies have shown that Reflexology can reduce
preoperative anxiety. We assessed the effectiveness of standard ofcare combined with Reflexology or Sham Reflexology, versus standardof care alone, in reducing preoperative anxiety in patients undergoing
Laparoscopic Cholecystectomy.
Methods: We conducted a Single Blind Randomized Controlled Trial
in Bnai Zion Medical Center in Haifa. (The completed study will include approximately 300 patients divided into three equal groups of 100each): Reflexology with Sandard Of Care (SOC); Sham Reflexology with
SOC; and SOC alone. Patients were assessed for anxiety using VAS-A(Visual Analogue Scale for Anxiety) questionnaires before and at entry
to the holding room area. Prior to transfer to the surgery theatre, thesame evaluation was repeated.
Treatment protocol: standard treatment included premedication
with anxiolytics (Oxazepam and Diazepam) according to the anesthesiologist’s decision. Reflexology and Sham Reflexology treatments were provided for approximately 15 minutes by a therapist.
Main Results: 135 patients participated in the study so far. Preoperatively, Reflexology (5.5-2.6, p<0.001) and Sham Reflexology (5.4-3.6,
p<0.001) treatments were associated with a significant reduction inanxiety level, but without significant clinical and statistical change (difference VAS-A=1.00, p=0.19). Comparison of mean anxiety showedsignificant improvement in the Reflexology group compared to the
SOC group (p < 0.0001). In contrast, severe anxiety (VAS>7) indicateda significant clinical and statistical difference between the Reflexology
group and Sham Reflexology (difference VAS-A=2.1, p = 0.01). Conclusions: Reflexology treatments combined with SOC reduce severe
preoperative anxiety significantly, compared to Sham Reflexology andstandard treatment alone. In light of the scope of preoperative anxiety and its implications for public health, the combination of Reflexology therapy with SOC should be considered for reducing preoperative
anxiety.

Correspondence to:Attias SamuelE-mail: samuel.attias@b-zion.org.il

100

BOOK OF ABSTRACTS | 12th European Congress of Integrative Medicine · 1st International Symposium on Integrative Health and Education

Title: Interoceptive Awareness in Studies
of Mind-Body Therapies: a Review of Research Studies
Wolf Mehling1
1
University of California San Francisco
Objective: Interoception is the sense of the state of the body. Interoceptive awareness is the awareness of sensations from inside thebody. Enhancing interoceptive bodily awareness is a key mechanismof action for mind-body therapies, such as meditation, mindfulness,yoga, tai chi, Feldenkrais, Alexander, Breath Therapy etc. The Multidimensional Assessment of Interoceptive Awareness (MAIA) is a self-report measure that has been translated into 20+ languages, undergone
numerous validation studies, and is applied worldwide in mind-bodyresearch. This review summarizes some of the best research that hasapplied the MAIA.
Material and Methods: Summary results from the following published studies will be presented:
1)
3 months of contemplative training changes interoceptive
awareness2)
8 weeks of Mindful Awareness in Body-oriented Therapy
for women with chemical dependency
3)
8 weeks of Mindfulness-Based Cognitive Therapy for comorbid depression and chronic pain
4)
12 weeks of Integrative Group Exercise for war veteranswith PTSD
5)
2 ½-day weekend workshop Mind in Labor based on Mindfulness-Based Childbirth andParenting education
6)
A 7-day 25 minutes mindfulness training for depression
7)
Neural correlates (fMRI) of MAIA scores in healthy subjects
and in obsessive compulsive disorder
8)
MAIA scores at baseline predict treatment responses in patients with chronic low back pain
Analysis: narrative review
Results: Data from a variety of longitudinal studies including RCTs
suggest that mind-body therapies differentially improve regulatory
dimensions of interoceptive bodily awareness, which mediate thetherapies effects on health benefits and correlate (cross-sectionally)
with fMRI findings.
Discussion/Conclusion: This review demonstrates that interoceptive bodily awareness is a key parameter in mind-body therapies, andthat the MAIA is an appropriate self-report measure for its assessment in research.

Correspondence to:
Wolf Mehling
E-mail: Wolf.Mehling@ucsf.edu

Title: Association between metabolic diseases
and blood stasis: a survey of Korean medical doctors
Soobin Jang1, Mi Mi Ko1, Byoung-Kab Kang1,
Seong-Hwan Park1, Jeeyoun Jung1
1
Korea Institute of Oriental Medicine
Background: Blood stasis is defined as slowing or pooling of bloodand according to Korean medicine, it is regarded as a cause of metabolic diseases, including hyperlipidemia and atherosclerosis. The aimof this study was to present the opinions of Korean medical doctors(KMDs) on metabolic diseases with blood stasis.
Methods: A survey was conducted by Korea Institute of Oriental
Medicine research team via Mediresearch, an online research company. The questionnaire consisted of questions relating to the perception of and the current state of treatment of metabolic disease related
to blood stasis. The survey period was between October 2 and 18,
2018. All statistical analyses were performed with R 3.4.3 software.
Results: Of the total 908 KMDs, 609 (67.1%) answered that metabolic diseases are highly associated with blood stasis and 227 (25.0%)
responded that blood stasis is the cause of metabolic diseases. The
diseases most associated with blood stasis were as follows: vasculardisease (n=405, 44.6%), heart disease (n=275, 30.3%), hyperlipidemia(n=157, 17.3%), diabetes mellitus (n=39, 4.3%), and hypertension(n=32, 3.5%). Most respondents thought that herbal medicine combined with conventional drug is good for managing blood pressure,
blood sugar, and blood lipids (n=724, 79.7%), and that the higher costcompared to conventional drugs (n=463, n=51.0%) is the reason why
herbal medicine is not frequently used for metabolic disease treatment. Among the herbal medicines for blood stasis, Gyejibongnyeong-hwan and Cardiotonic pills were chosen as the appropriate herbal
medicines for treating metabolic diseases and for being covered under herbal medicine insurance.
Conclusions: This study provides practical evidence for further
blood stasis research and suggests the necessity for exploratory clinical studies to determine the association between blood stasis andmetabolic diseases.

Correspondence to:
Soobin Jang
E-mail: soobeenee2@gmail.com

BOOK OF ABSTRACTS | 12th European Congress of Integrative Medicine · 1st International Symposium on Integrative Health and Education

Title: Herbal medicines for metabolic diseases with blood stasis: A systematic review and meta-analysis

101

Title: The Effects of Surgery on Plasma
Vitamin C Concentrations and Cognitive
Function

Mi Mi Ko1, Soobin Jang1, Jeeyoun Jung1, Youme
Ko2
1
Korea Institute of Oriental Medicine
2
Kyung Hee University

Nikolaj Travica1, Karin Ried2, Irene Hudson1, Andrew Scholey1, Andrew Pipingas1, Avni Sali2
1
Swinburne University of Technology
2National Institute of Integrative Medicine

Objectives: Herbal medicines have the potential to be alternative
treatments for metabolic diseases. The systematic review aims to assess the efficacy and safety of herbal medicines in treating metabolic
diseases with blood stasis.
Materials and Methods: We searched seven databases for studies
published through May 2018. We included all randomized controlled
trials (RCTs) or quasi-RCTs evaluating the effectiveness of herbal
medicine. Participants of both sexes and of any age with clinicallydiagnosed metabolic disease with blood stasis were included. Data
extraction and risk-of-bias assessments were performed by two independent reviewers. The risk of bias was assessed using the Cochrane
tool for assessing risk of bias. Primary outcomes included Blood-stasis syndrome score, TC, TG, HDL-C and LDL-C. Secondary outcomes
included blood pressure, FBS. ECG, prevalence rate of heart disease,and response rate.
Results: Nine RCTs met our inclusion criteria. In the studies thatcompared herbal medicine with Western medicine or placebo, theherbal medicine resulted in a significant reduction in blood stasis
scores (SMD -0.80, 95% CI -1.50 to -1.0; P = 0.03). The effect of theherbal medicine intervention remained significantly better than thatof others treatments (OR 3.41, 95% CI 2.33 to 4.97; P < 0.01), and theheterogeneity among the studies was no heterogeneity (I2 = 0%, P =0.80).
Discussions: Our review provided suggestive evidence of the effectiveness of herbal medicines for metabolic disease with blood stasis.
However, these results are based on relatively few trials with small
sample sizes. More high-quality studies are still needed to provide robust evidence.
Conclusions: The findings of this study provided a summary of thecurrent state of evidence regarding the effectiveness of types of herbal medicine in managing metabolic disease with blood stasis.

BackgroundPost-operative cognitive dysfunction (POCD) is characterised by asignificant cognitive impairment following a surgical intervention, affecting an estimated average of 35% of non-cardiac surgical patients.
Our recent systematic review and cross-sectional study indicated that
there is an association between plasma vitamin C concentrations andcognitive function, with higher concentrations correlating with higher
cognitive performance.
Objectives
The aim of the present study was to determine whether deficiencies in plasma vitamin C concentrations following orthopaedic surgery
is a potential contributor to POCD.
Methods
We conducted a meta-analysis which assessed changes in post-operative plasma vitamin C concentrations in a number of trials. We
are currently undertaking a prospective cohort study recruiting elderly (>60 yrs.) patients undergoing orthopaedic surgery (hip/knee
arthroplasty). These patients are having their cognitive function andplasma vitamin C assessed alongside a number of potential covariates
1-2 weeks before surgery and 1-2 weeks,1 month, 3 months and 6
months after surgery. Cognition was assessed using a number of paper and pen assessments and a validated computerised assessment
battery.
Results
Based on seventeen studies, our meta-analysis results revealed asignificant depletion (p < 0.001) in short-term (7 days) and longer-term(>7 days) post-operative plasma vitamin C concentrations. Additionally, the results of one tested patient (case-study) who had undergone
total knee arthroplasty demonstrated a substantial post-operativeplasma vitamin C depletion alongside compromised cognitive function on short term and long term recall, attention and focus, based on
the cognitive assessments.
Conclusion
Based on our meta-analysis, previous studies have systematicallydemonstrated significant post-operative plasma vitamin C depletions.
Additionally, our case study demonstrated a prominent depletion inplasma vitamin C concentrations alongside compromised cognitive
function post-operatively. Further testing will confirm whether depletions in plasma vitamin C concentrations following orthopaedic surgery are a feasible contributor to POCD.

Correspondence to:
Mi Mi Ko
E-mail: kmm1836@gmail.com

Correspondence to:
Nikolaj Travica
E-mail: nikolaj_travica@hotmail.com

102

BOOK OF ABSTRACTS | 12th European Congress of Integrative Medicine · 1st International Symposium on Integrative Health and Education

Title: Chronic fatigue syndrome and bloodlevel of some hormones

Title: Levels of some biochemical parameters in subjects with high blood pressure

Slobodan Dunjić1, Jovana Pejić1, Emilija Filipović2,
Miloš Maletić1, Petar Kraković1, Vida Subotić3
1Center for Integrative Procedures and Supplements ‘’Dr Dunjić’’, Belgrade, Serbia
2Institute for Radiology and Oncology of Serbia,
Belgrade, Serbia
Center for Integrative Procedures and Supplements ‘’Dr Dunjić’’3
Zdravlje pharm, Brčko Distrikt, Bosnia and Herzegovina

Slobodan Dunjić1, Jovana Pejić1, Emilija Filipović2,Dana Stojičić1, Milica Lojić1, Vida Subotić3
1Center for Integrative Procedures and Supplements ‘’Dr Dunjić’’, Belgrade, Serbia
2Institute for Radiology and Oncology of Serbia,
Belgrade, Serbia
3
Zdravlje pharm, Brčko Distrikt, Bosnia and Herzegovina

Background
Chronic fatigue syndrome (CFS) is a serious, long-term illness that
affects many systems of human body. So far, the cause of this condition is not known. CFS symptoms can include severe fatigue, sleep
problems, loss of focus and concentration, dizziness etc. Aside othertreatment methods, personal-holistic approach in healing may help topatients suffering from CFS.
Objective
The aim of the paper is to present relation that we found between
presence of CFS symptoms and some biochemical parameters, including hormones.
Material and methods
Laboratory analysis of both, male and female patients was statistically analyzed. Patients were divided into two groups: group with nopresence of CFS symptoms (noCFS), and group with presence of symptoms - CFS. All of patients were recruited from Center for Integrative
Procedures and Supplements “Dr Dunjić”, Belgrade (the Center). Holistic-personalized approach in patients healing was performed in theCenter. Statistical analysis was done by using Statistical Package forSocial Sciences (SPSS).
Results and discussion
Total number of patients was 1048. There were 648 males (61,9%),and 400 females (38,1%). noCFS group counts 446 subjects (42,5%),
while CFS group counts 602 subjects (57,3%). Mean age was 43,2+14,8yrs vs. 47,2+-14,1 (p=0,000). Blood sugar level was 5,38+-1,1 vs.
5,55+-1,5; p=0,049. fT3 level was 4,96+-1,05 vs. 4,75+-1,09; p=0,012.
Vitamin D level was 63,72+-28,9 vs. 57,8+-28,3; p=0,002. Cortisol levelat 4PM was 220,7+-105,6 vs. 250,1+-110,7; p=0,006.
Conclusion
The study revealed that subjects with presence of CFS had significant lower value of fT3 in their blood, as well as vitamin D. On theother side, level of cortisol in afternoon hours in those subjects was
significantly higher than in those who did not report symptoms of CFS.
At last, blood sugar level showed to be higher in people with CFS, but
statistical significance was at border-line.

Correspondence to:
Slobodan Dunjić
E-mail: ordinacija@drdunjić.rs

Background
High blood pressure (hBP) is a major risk factor for coronary heartdisease, ischemic, and hemorrhagic stroke. hBP is estimated to cause 7.5 million deaths worldwide. Aside conventional methods of highblood pressure treatment, holistic approach also plays an importantrole.
Objective
The aim of the paper is to present relation that we found between
presence of high blood pressure and some biochemical parameters.
Material and methods
Laboratory data of both, male and female patients were statisticallyanalyzed. Patients were divided into two groups: group with no presence of high blood pressure (noBP), and group with presence of highblood presence (BP). All of patients were recruited from Center for
Integrative Procedures and Supplements “Dr Dunjić”, Belgrade (theCenter). Holistic-personalized approach in patients healing was performed in the Center. Statistical analysis was done by using Statistical
Package for Social Sciences (SPSS).
Results and discussion
Total number of patients was 1045. noBP group counts 724 subjects (69,2%), while BP group counts 321 subjects (30,8%). Mean age
was 41,8+-13,16yrs vs. 53,9+-14,2 (p=0,000). Blood sugar level (BSl)was 5,3+-1,01 vs. 5,9+-1,8; p=0,000. HbA1c level was 5,14+-0,51 vs.
5,43+-0,9; p=0,000. Erythrocyte sedimentation rate (ESR) was 16,4+1,8 vs. 24,0+-2,21; p=0,005. Total cholesterol level (tCl) was 5,22+-1,18
vs. 5,5+-1,27; p=0,003. HDL cholesterol was 1,5+-0,44 vs. 1,4+-0,46;
p=0,003. LDL cholesterol was 3,03+-0,95 vs. 3,31+-1,06; p=0,001. Triglycerides level was 1,34+-0,93 vs. 1,72+-1,3; p=0,000. Uric acid (UA)level was 279,3+-82,7 vs. 321,0+-91,3 p=0,000.
Conclusion
These findings point that hBP is accompanied with numerous biochemical changes such are elevation of BSl, HbA1c, tCl, LDL cholesterol, triglycerides, UA, and ESR. HDL level was lower in BP group which
was expected. All of these findings are well known risk factors for onset/development of hBP; however, an elevation of ESR and UA should
be more studied.

Correspondence to:
Slobodan Dunjić
E-mail: ordinacija@drdunjic.rs

BOOK OF ABSTRACTS | 12th European Congress of Integrative Medicine · 1st International Symposium on Integrative Health and Education

Title: Interesting laboratory findings in female patients with inability to conceive
Slobodan Dunjić1, Miloš Maletić1, Petar Kraković1,
Dana Stojičić1, Milica Lojić1, Vida Subotić2
1Center for Integrative procedures and Supplements “Dr Dunjić”, Belgrade, Serbia
2
Zdravlje pharm, Brčko Distrikt, Bosnia and Herzegovina
Background
Infertility is common heath problem worldwide today. It is definedas trying to get pregnant for at least a year with no success. Female
infertility, male infertility or a combination of the two, affects 10 to 18
percent of couples in USA.
Objective
The aim of the paper is to present laboratory results we found infemale patients facing infertility in relation to those who did not haveconceiving problems.
Material and methods
Laboratory analyses of female patients were statistically analyzed.
Female patients were divided into two groups: control group withno-conceiving problem (N) and group having an infertility problem (I).
All of patients were recruited from Center for Integrative Procedures
and Supplements “Dr Dunjić”, Belgrade (the Center). Holistic-personalized approach in patients healing was performed in the Center. Statistical analysis was done by using Statistical Package for Social Sciences(SPSS).
Results and discussion
430 female subjects were included into study; N group counts 397
subjects (92,3%) and I group counts 33 subjects (7,7%). Mean age was
36,5+-8,4 vs. 36+-4,5 (p=0,744). Homocysteine level (H) was 11,4+-5,8
vs. 19,5+-7,8 (p=0,036). Prolactine level (P) at 4PM was 371,9+-23,8
vs. 572,9+-49,6 (p=0,003). Free thyroxine (fT4) was 15,8+-3,8 vs. 14+3,2 (p=0,048). Free triiodothyronine (fT3) was 4,8+-0,8 vs. 4,4+-0,9(p=0,076).
Conclusions
Female patients facing infertility had an elevated level of homocysteine in their blood. Today, there are some researches which try to
identify the possible role of homocisteine in inability to conceive andthis finding requires more attention of scientists in time to come. Also,
it is found that females in I group had increased prolactine level during
afternoon hours in comparison to N females. The levels of fT3 andfT4 hormones in infertile females were slightly lower in comparison
with N group of subjects, but no statistically significant difference wasfound.

Correspondence to:
Slobodan Dunjić
E-mail: ordinacija@drdunjic.rs

103

Title: Cinnamomum camphora ameliorates
cognitive impairment and promotes neuroprotection in mouse model of Alzheimer’s disease
Yunna Kim1, Yongju Kwon1, Seung-Hun Cho1
1
Department of Korean Neuropsychiatry, Kyung
Hee University, Seoul, South Korea
Objectives: Even though Alzheimer’s disease (AD) is one of theleading causes of cognitive impairment, its etiology is not well known,
and an effective treatment has not been established yet. Many herbs
have been suggested as candidate therapeutics for AD as multi-target
agents. We investigated the therapeutic effect of Cinnamomum camphora using amyloid β (Aβ) mouse model of AD.
Materials and methods: Pathological features were induced by an
intrahippocampal injection of Aβ1-42. C. camphora was orally administered, and donepezil and a vehicle were administered as control.
Behavioral changes in spatial learning and memory were tested using
the Morris water maze and Y-maze tests, and the levels of proteins
related to memory and neuroprotection were determined by immunoblotting and immunohistochemistry.
Results: A noticeable impairment of learning and memory developed after an infusion of Aβ into the hippocampus. Administrationof C. camphora reduced the memory deficit in the behavioral tests,
especially at a dose of 200 mg/kg. The results of immunoblotting andimmunohistochemistry demonstrated that C. camphora inhibited theneurotoxic effect of Aβ, as shown in decreased deposition of Aβ itself and reduction of neuronal loss and glial activation. C. camphorademonstrated the same efficacy as donepezil in reversing the protein
levels of brain-derived neurotrophic factor (BDNF), phosphorylated
extracellular signal-related kinase (ERK), and phosphorylated cyclic
AMP response element binding (CREB) protein, which were reduced
by Aβ.
Conclusions: In conclusion, C. camphora significantly improved thememory function in a mouse model of AD with a mechanism of neuroprotection manifested through the BDNF-ERK-CREB pathway.

Correspondence to:
Yunna Kim
E-mail: yunna.anna.kim@khu.ac.kr

104

BOOK OF ABSTRACTS | 12th European Congress of Integrative Medicine · 1st International Symposium on Integrative Health and Education

Title: Effects of two mushroom extracts on
symptom alleviation in osteoarthritis patients: Pilot Study
Catalina Fernández de Ana Portela , Ingrid Moller ,Ivan Simón Gómez1, Arturo Rodriguez Blanco1, Esteban Sinde Stompel1, Josep Vergés Milano3
1
Hifas da Terra S.L.
2
Institut Poal de Reumatologia
3
Osteoarthritis Foundation International
1

2

Objective
To assess the efficacy, safety and tolerability of a daily oral dose of
two combined edible mushroom extracts, obtained from cultured
Cordyceps sinensis, Ganoderma lucidum, Grifola frondosa, Lentinula
edodes and Agaricus brasiliensis, given over three months to patientswith symptomatic Osteoarthritis
Materials and Methods
This observational study was performed in a group of 20 patientswith knee-osteoarthritis (Kellgren and Lawrence grade II or III). They
were 58 years-old on average, 80% women; with BMI 25.8 on average; 80% with no hypertension and 85% non-smokers. During thefirst 2 months, extracts were given twice a day, whereas dosing was
reduced to once a day during the third month.
Analysis
Changes induced by extracts were assessed, before and after treatment, using the WOMAC Index, which evaluates pain, stiffness andphysical function, and the visual analogical scale for pain (VAS). In addition, inflammation was evaluated by echography grey scale. Only
an improvement equal or greater than 20% was considered as significant.
Results
According to WOMAC questionnaire, 80% of the cohort reported
an improvement of at least 15%, 63% of which exceeded the 20%.
Fifty percent of the parameters presented a 20% improvement on thepain perception such as walking on a plain surface (25%) or gettingout of bed (22.4%).
Before treatment, an average VAS for pain scale of 6,4±0,45 wasreported, and 25% of the patients showed inflammation signs, as
shown by ecography. After 3-months treatment, 75% of patients
showed an improvement on the pain scale, with an average value of
4,9±0,55, which represents a 23.4% improvement.
Discussion and Conclusions
Pain and stiffness improvement in Osteoarthritis patients after
mushroom extracts treatment was in the range of values reported forchondroitin sulphate and glucosamine treatments. However, patients
reported an enhanced physical function and energetic capacity, whichadds an extra value to micotherapy.

Correspondence to:Catalina Fernández de Ana Portela
E-mail: xerencia@hifasdaterra.com

Title: Series study of cases treated with
Energy Regulation Therapy ()Idoia Negrete Pérez1, Lourdes Moratinos OloronSaint Marie2, Paula Olaz Moratinos1
1
Universidad Europa Viadrina Frankfurt Oder2
Clínica De Regulación EnergéticaOBJECTIVES. The purpose of this study is to publicise Energy Regulation Therapy (ERT) and to verify its effectiveness through scientificstudy. MATERIAL AND METHODS. Patients of different pathologies
who attend the ERT consultation in Pamplona. Generally, finding nosolution to your disease with Conventional Medicine. This study includes 17 cases between 2006 and 2019, which make up this descriptive
observational case series study. ANALYSIS. Variables analysed: age,gender, type of pathology, time to attend ERT, number of ERT treatments, conventional medical treatments prior to ERT, effectiveness of
ERT and cure of pathologies with ERT. RESULTS. 17 cases described,
mean age of 39 years (between 5 and 75 years old), female predominance 70.6%. Case pathologies: depression, infertility, amenorrhea,
anaemias (megaloblastic and iron deficiency), oncological pathologies(brain tumour, breast cancer, metastases and prostate cancer), Rett
syndrome, congenital heart disease, Diabetes Mellitus, chronic pharyngitis, anal fissure, Neurapraxia of the radial nerve, gastrointestinal disorders, vaginitis and HPV. The time to go to the ERT from the diagnosis was variable between 1 day to 9 years. The number of treatments
was variable between 5 and 80 treatments. In all cases treated with
ERT no future pharmacological treatment was necessary. The effectiveness of ERT was 100% in all cases. DISCUSSION. ERT is effective inall the pathologies studied. The variables of this study demonstratethat each case is unique and the treatment is individualised, always
ending in the healing of the patient. Cure is confirmed through clinicalreports. CONCLUSION. Given the positive and striking results of thisstudy, we believe there is a need to carry out further and more extensive future studies in order to include it in Integrative Medicine andstudy it officially.

Correspondence to:
Idoia Negrete Pérez
E-mail: idoia.negrete@gmail.com

BOOK OF ABSTRACTS | 12th European Congress of Integrative Medicine · 1st International Symposium on Integrative Health and Education

Title: Influence of cocoa drink product, on
acute physical stress, in sedentary persons
Ramona Jurcău*1, Ioana Jurcău2, Mihai Kiss3, Cornelia Popovici3
Department of Pathophysiology, Faculty of Medicine, „Iuliu Hațieganu” University of Medicine andPharmacy, Cluj-Napoca, Romania
2Emergency Clinical Hospital for Children, Cluj-Napoca, Romania
3
Department of Physical Education and Sport, Faculty of Medicine, „Iuliu Hațieganu” University of
Medicine and Pharmacy, Cluj-Napoca, Romania
1

Background: Physical exercise constitutes a stress factor. On theother hand, Cocoa (CO) is know for its anti-fatigue and antioxidant
effects. The objectived of the study was to evaluate the influence ofa cocoa drink product (COP), on acute physical stress, in sedentary
persons.
Material and method: The chosen stress model has been a shortand intense exercise, accomplished by walking very fast on thetreadmill, for 12 minutes. 24 voluntary healthy men subjects wererandomized divided, in control group (C=12) without treatment andgroup that received COP (CO=12). Subjects of CO received COP for 21
days before subjecting them to stress. The analyzed indicators were
fatigue (FT), determined by questionnaire, and heart rate (HR). The
parameters determinations were made 24 hours (T1), 15 minutes(T2) before, 30 minutes (T3) and 4 hours (T4) after the physical effort.
Statistical evaluation was based on the Student t test.
Results: It was found that for C compared to T1, the most significant
increases were at T2 for HR and at T3 for FT. In the CO compared to C
values were significantly low for HR at T2 and for FT at T3. At T3, the
COP impact in CO was similar on HR and FT.
Conclusions: 1) There were differences for the dynamic developments of state of HR and FT, between the C and CO. 2) Under the
COP influence HR and FT were significantly reduced in treated compared to untreated subjects, in the immediately pre and respectively
post stress moments. 3) Influence of the COP was similar on HR and
FT, in immediately post- stres moment. 4) We suggest COP use for
HR and FT modulation, in stress caused by walking very fast on thetreadmill, in sedentary people.

Correspondence to:Ramona-Niculina Jurcau
E-mail: ramona_mj@yahoo.com

105

Title: Non-invasive brain stimulation in thetreatment of chemotherapy-induced neuropathy
Carolina, Juan carlos Romero, Durán1
1
ULL, Hospital de San RoqueIntroduction:
Chemotherapy-induced Neuropathy (CIPN) is a limiting factor in active cancer treatment. It causes delays in a new cycle, dose reduction
or even treatment suspensions (1). The symptoms caused by CIPN impair daily activities and the quality of life of patients (2-3-4-5-6). Its incidence reaches 80% of cases in drugs such as paclitaxel (widely usedin breast, ovarian or lung cancer). CIPN is an invalidating complication
where 30-50% of cases develop chronic neuropathy.
Currently, pharmacological treatment is very limited. However, recent studies published by Prinsloo et al. (MD Anderson Cancer Centre,7) with the Neurofeedback in the treatment of CINP, open a new lineof research in neuromodulation, with a limiting side effect.
DesignRandomised, double blind clinical trial.
Objectives:
According to bibliographic data, we believe that neuromodulation
could help reduce CIPN symptoms and achieve greater adherence totreatment. The main purpose of this research is to analyse the efficacyof treatment with NFB and tDCS against the control group.
As a secondary objective, assess the degree of synergy between
both non-invasive brain stimulation treatments.
Materials and method:
The representative sample is of 60 patients that meet the defined
inclusion and exclusion criteria. The methods used EEG, NFB, tDCS,
and validated surveys.
• Electroencephalogram (EEG) is a measure of the electrical activity
of synchronised cortical neurons.
• Neurofeedback (NFB) is a therapeutic modality that, through theuse of brain waves, allows us to be aware of the brain activity itself
and modify it.
• Transcranial direct current (tDCS). It is a type of brain electricalstimulation, a non-invasive neuromodulation technique used to modulate neuronal excitability.

Correspondence to:Carolina, Juan carlos Romero, Durán
E-mail: lagranpaznatural@gmail.com

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BOOK OF ABSTRACTS | 12th European Congress of Integrative Medicine · 1st International Symposium on Integrative Health and Education

Title: Effect of acupuncture on autonomic
nervous system of hemodialysis patients :A randomized, double-blind, placebo-controlled trial

Title: A New Discovered Chakra 3.5 “Janika” could be the missing link in the future
research for integrative treatment of theMetabolic Syndrome

Hinata Sakuraba1, Satoshi Ayuzawa1, Tomomi
Narushima1, Shigeru Ohwada2, Aki Hirayama1
1Center For Integrative Medicine, Tsukuba University Of Technology, Japan
2
Asao Clinic, Japan

Yannick Pots1, Baro Deressa2, Christel Fontaine3
1
VUB Brussels
2
CHU Brugmann
3
UZ Brussel

OBJECTIVES: Hemodialysis (HD) patients often complain of fatigue
and dullness after HD, and these symptoms are thought to affect theirautonomic nervous system activity. Additionally it remains unknown
whether acupuncture affects post-HD orthostatic tolerance. In thisstudy we investigated the effect of acupuncture on the autonomic
nervous system function of HD patients by assessing active standing
load.
METHODS: This study was designed double-blinded, randomized,
placebo-controlled. Twenty-two patients (10 males : 12 females,64.2±12.3 years old, HD periods; 4.2±4.0 years) were assigned to acontrol group (no intervention), to a treatment group that received
acupuncture with 0.6mm press tach needle (Pyonex, SEIRIN, Japan)
and to a placebo group. We evaluated autonomic nervous system
activity before and after HD using frequency analysis of heart ratevariability in the orthostatic tolerance test (Kiritsu-Meijin, Crosswell,Japn). Statistical analyses were performed using linear mixed effectmodel with a P value of < 0.05. We used software the R ver. 3.5.0(https://www.r-project.org/). RESULTS AND DISCUSSION: The control group was 8 (4:4, 61.7±10.6, 5.8±4.2), the treatment group was
7 (3:4, 69.0±11.5, 3.1±3.2), the placebo group was 7 (3:4, 62.3±13.6,
3.5±3.8). There were no significant differences in heart rate (ΔHR),
autonomic nerve activity (ΔCVRR), sympathetic and parasympathetic
nerve activity (ΔLF/HF and ΔHF) on orthostatic tolerance test. In allgroups, ΔHR tended to increase after the measurement, we thoughtthat these results were related to HD. This study was supported by
JSPS KAKENHI Grant Number JP17K09291.
Disclosure: No potential conflict of interest (COI) to disclose.
Correspondence to:
Hinata SAKURABA
E-mail: hinata@k.tsukuba-tech.ac.jp

Background: Major causes of death(s) are disorders/doshas situated at Water- resp. Earth-subdoshas-level (sd-L). Water-sd-L disorders
including endocrine/metabolic diseases (3.8 mio), and diseases of
the circulatory system (17.9m), as well as Earth-sd-L disorders suchas diseases of respiratory system (7.9m), and neoplasms (9.6m), areresponsible for about 40 mio/72% of all deaths (56.9m, globally, 2016)
according to WHO.
Aim: To describe how the new chakra 3.5 “Janika” was discovered
and could lead to integration of the Ayurvedic Medicine as a new
strategy for treating metabolic syndrome.
Methods: We integrated all three, Hinduism-Philosophy mindset and it’s i.c. seven chakras, Eastern-Medicine mind-set and it’si.c. Ayurvedic (global) classification of doshas/disorders, and Western-Medicine mind-set and it’s i.c. (international) classification of diseases(version 11).
Results: By integrating the three different mind-sets, we could
create a new transdisciplinary 15-minor/1-major framework. We
connected the opposite corners of the major-matrix, and obtained amatrix juncture just in the middle of the lower stomach and the small
intestine, identified as the 3.5 chakra. According to anatomy/physiology, the 3.5 chakra is situated at the Papilla vateri where arrives bothdigestive radices: the pancreas and resp. gallbladder secretions. Gallic
acid, an active component from Terminalia bellirica fruit is known tohave hypoglycemic, hypolidemic, and antihypertensive properties.
In vitro it could inhibit the pancreatic lipase activity and enhance thesecretion of adiponectin via adipocyte differentiation. Therefore Terminalia bellirica fruit shows promise as a good research candidate fortreating patients with metabolic syndrome.
Conclusion & Significance. Integration of all three, Hinduism-Philosophy-, Eastern-Medicine-, and Western-Medicine- mind-sets leads tocreation of a new transdisciplinary framework and a new Chakra 3.5
called “Janika” as a missing link for future research in preventive medicine, in particular for the metabolic syndrome.

Correspondence to:
Yannick Pots
E-mail: christel.fontaine@uzbrussel.beBOOK OF ABSTRACTS | 12th European Congress of Integrative Medicine · 1st International Symposium on Integrative Health and Education

Title: Medicinal mushrooms: A review ofscientific evidence from systematic reviews and meta-analysis
Saskia Kloppenburg Vieth , Sergio Abanades
1
NADclinic, London
2
Integrative and Conscious Health Institute, Barcelona, Spain
1

2

Background: There has been a significant increase in the use ofmushrooms for medicinal purposes. The potential role that medical
mushrooms can have as a complementary therapy alongside conventional medicine is of wide range interest.
Objective: To review the best evidence available at present about
the clinical effects medicinal mushrooms can have, assessing both objective and subjective benefits.
Methods: A systematic bibliographic reach was carried out including only the highest level of evidence as limited to systematic reviews
and meta-analysis published up to October 2018, with a total of 21
key-words being searched.
Results: for Ganoderma Lucidum 2 systematic reviews from the
Cochrane Library are available. In cancer patients, a meta‐analysis of 5 RCTs showed that patients who had been given G. lucidumalongside with chemo/radiotherapy were more likely to respond positively compared to chemo/radiotherapy alone (RR1.50; 95%CI:0.902.51,P=0.02). In cardiovascular patients, evidence from a small
number of RCTs does not support the use of G. lucidum for treatment of cardiovascular risk factors. Regarding Corolius Versicolor, ameta-analyisis on survival in cancer patients from 13 RCT, showed a
9% absolute reduction in 5-year mortality, in addition to chemo/radio-therapy. An individual patient based meta-analysis of Lentinula
edodesin recurrent/inoperable gastric cancer showed an increase
global survival rate (RR 0.80, 95%CI 0.68-0.95). Cordyceps Sinensis andShiitake amongst other species could reduce toxicity of chemotherapy
and radiotherapy. For other mushrooms such as Agaricus Blazei or Hericium erinaceus limited data were available.
Discussion: This review only included systematic reviews and meta-analysis limiting the overall evidence. High quality evidence from
non-patentable medicines such as medicinal mushrooms is hard to
obtain.
Conclusions: Although more research is required, the role of medicinal mushrooms as complementary therapy seems to be promising.
Evidence coming from meta-analysis of RCTs is available. However,more in depth and better quality research is required.

Correspondence to:
Saskia Kloppenburg Vieth
E-mail: saskiakv@gmail.com

107

Title: Ketogenic diet for dog with Brain Tumor
Jacquelyne Motta1, Fabiola Donadao2, Viviane Raposo3
1
University of Florida
2
American Council of animal naturopathy
3
UVV
Objectives
This case is here to demonstrate the effectiveness of the Ketogenic
Diet (KD) as adjunctive therapy in the treatment of brain tumor. The
KD is an effective non-toxic metabolic therapy that can provide anti-angiogenic and pro-apoptotic mechanisms.
Methods
Simba, a male Golden Retriever with severe seizures, caused due
to a brain tumor detected by magnetic resonance imaging (MRI)
was submitted on a KD. The KD is a high-fat/low-carbohydrate/adequate-protein diet has recently been proposed as adjuvant therapy
in cancer treatment. Consists in the replacement of carbohydrates
by healthy fats, which are converted to ketones, and in the intake ofmoderate amounts of high-quality protein to metabolize ketone bodies as an alternative fuel, when glucose availability is low.
Analysis
These tumors vary widely in their level of malignancy and, unfortunately, there is still much that we still do not know about how different types of brain tumors behave in dogs. In Simba’s case, it suggeststhat tumor cells have reduced the ability to metabolize these ketone
bodies for energy.
Results
After two months on a KD, the inflammation associated with thetumor was completely reduced, in addition, the fibrosis being visible
and no additional neurological deficits were found.
Discussion
There are alternatives other than conventional medicine. Diet must
be included on therapy plans either as an adjuvant or whenever possible as the main treatment. Nutrition plays an important role in the
future of Medicine.
Conclusion
Integrative Medicine conducted with criteria and responsibility
leads to health and vitality for patients. Participants will know about
this non-toxic alternative to help their patients and themselves.

Correspondence to:
Jacquelyne Motta
E-mail: jackmottavet@gmail.com

108

BOOK OF ABSTRACTS | 12th European Congress of Integrative Medicine · 1st International Symposium on Integrative Health and Education

Title: Association between Living environment and allergic rhinitis in the Korean
adult population: the Korean National
Health and Nutrition Examination Survey
2013-2017
Ching-Wen Huang , Seong-Gyu Ko , You-Me Ko , Yui
Sasaki3, Bo-Hyoung Jang2
1
Department of Science in Korean Medicine, Graduate School, Kyung Hee University, Seoul, South Korea
2
Department of Preventive Medicine, College of Korean Medicine, Kyung Hee University, Seoul, Korea
3
Department of Applied Korean Medicine, Graduate
School, Kyung Hee University, Seoul, South Korea
12

3

Objectives:
The living environment is one of the important determinants forpromoting health. This study aims to investigate the relationship between Living environment factors and allergic rhinitis in Korean adults.
Material and method:
The data from 2013-2017 Korea National Health and Nutrition Examination Survey (KNHANES) was used in this study.
Analysis:
To analyze the predictive variables of allergic rhinitis, we used multivariable logistic regression, with allergic rhinitis as the dependent
variable and demographic variables (age, sex, household income,academic background, marital status, chronic disease (hypertension,diabetes mellitus) and living environment factors (urbanization, apartment, house member number and Generation number) as independent variables.
Results:
Of the 31295 people in this study, 3740 (12.0%) with allergic rhinitis. Apartment and urbanization showed a significant association.
After adjusting for all confounders, who live in the urban, apartment,
and live with two generations has a higher ratio of allergic rhinitis with
Statistically significant. The adjusted odds ratio of who living in theapartment was 1.14 (95% CI 1.05-1.23), living in the urban area was
1.19 (95% CI 1.07-1.32) and live with two generations was 1.11 (95%
CI 1.00-1.23).
Discussion:
There are three types of AR; Congenital tracheal disease, allergen-related and neurological diseases induced. In Western medicine,allergic rhinitis is not a completely cured disease, only some drugs orsome other methods can be used to alleviate symptoms. In this study,
we focused on allergen-related AR, especially on Living environment
factors. We found that who live in the urban, apartment, and live with
two generations has a higher ratio of allergic rhinitis. Our result is similar to a previous study in the United Kingdom (2018) showed thatliving in conurbations or urban areas were higher prevalence in AR.
Conclusions:This study suggests that allergic rhinitis prevalence is significantly
associated with the Living environment in South Korea.

Correspondence to:Ching-Wen Huang
E-mail: sunnierlove@gmail.com

Title: Impact of health-related behaviors
on Metabolic Syndrome: using the Korea
National Health and Nutrition Examination Survey
Yui Sasaki1, Ching-Wen Huang1, Bo-Hyoung Jang1,
Seong-Gyu Ko1
1
Department Of Preventive Medicine, College Of
Korean Medicine, Kyung Hee University
Objectives: To identify differences of health-related behaviors between a non-metabolic syndrome group (Non-MetS) and a metabolic
syndrome group (MetS) in Korea.
Material and method: Data from the Korea National Health andNutrition Examination Survey (KNHANES) in 2015. We analyzed respondents who were over 20 years old and replied to all “Alameda7”
items: (1) Drinking less than three drinks in one sitting, (2) Having never smoked, (3) Sleeping 7-8 hours a night, (4) Having physical activity 1.25~2.5 hours a week, (5) BMI: 18.5≦~<25, (6) Eating snacks lessthan four times a month and (7) Eating breakfast 5~7 days a week.
Diagnosis conditions of MetS relied on three or more of the following:(1) blood pressure: 130/85 mmHg or above, (2) fasting blood glucose:
100 mmHg or above, (3) waist size: male 90 cm≦ / female 85 cm≦, (4)HDL-cholesterol: male 40 mg/dL or less / female 50 mg/dL or less, and(5) triglycerides: 150 mg/dL or above.
Analysis: We used a multiple logistic regression analysis with adjustment for a complex sample design to find which health-related behaviors would affect MetS as a risk factor.
Results: 3,229 out of 7,380 subjects met the set of criteria; furthermore, the prevalence of Non-MetS was 2,412 (74.7%) and MetS was
817 (25.3%). Significant risk factors for MetS were as follows: BMI of
25 or above (OR=9.29; 95% CI [7.32, 11.80]), physical activity less than
1.25~2.5 hours (OR=1.55; 95% CI [1.23, 1.95]) and drinking three ormore drinks (OR=1.50; 95% CI [1.13, 1.99]).
Discussion: Although BMI is an index of obesity, it has been also
highly associated with prevalence of MetS. It could be indirectly risk
factor because obesity could induce diabetes or dyslipidemia.
Conclusions: Our results showed that specific unhealthy behaviors– BMI, drinking alcohol and physical activity – were likely to be risk
factors for MetS.

Correspondence to:
Yui Sasaki
E-mail: jahaen22@gmail.com

BOOK OF ABSTRACTS | 12th European Congress of Integrative Medicine · 1st International Symposium on Integrative Health and Education

Title: Implications in lower members ofvestibular dysfunction
Peña Martín Romero1, Santiago Crucci2, Dr. Enrique De Juan Gonzalez De Castejón3, Laura Planas
Ortega2
1
Clínica Podológica Peña
2
UB
3
Clínica Doctor De Juan
The objective of the work we present is to understand the whole ofthe patient, we focus on the interrelation of two postural captors, thevestibular system and the foot captor.
The vestibular system, its relationship with the renal and vascularsystem as graviceptors. As well as its relation with the emotion andthe consequences that can be found in lower limbs.
In vestibular patients, the main consequences that we can observein the lower limbs are very common in the podiatrist’s consultation,
fascial tensions are observed that trigger myofascial trigger points.
These tensions can give symptoms that can be confused with plantar fasciitis, morton neuroma, aquilea tendinopathy, knee pain andeven lead to important deformities such as HAV and claw fingers.
The treatment of the patient with vestibular dysfunction should beapproached from a multidisciplinary approach.
From podoposturology we perform postural templates with theaim of restoring stability, it can also be complemented with the application of laser therapy for the release of trigger points.
The role of the physiotherapist with training in Posturology is important for the rehabilitation of the vestibular system.
It is interesting to complete the study of the assessment of the vestibular system with the listening tests based on Dr. Tomatis’ postulates. According to its principles, the way to listen to the serious tones(between 125 and 1000Hz) would be neurophysiologically related to
the vestibular apparatus.
Checking the relationship of the listening test with the vestibular
and its auditory assessment is part of this presentation.
If the patient presents a pathology at the foot level or some typeof symptomatology at this level, it is very important to consider that
there are different clinical situations present that can lead to produce
consequences or functional compensations at this level, one of them
are the alterations at the level of vestibular system.

Correspondence to:Peña Martín Romero
E-mail: pmrpodologa@gmail.com

109

Title: Microbloodletting in MC9 in cases ofArterial Hypertension
Patricia Natalia Dolcet Romeo1, Chiara Capece1
1
Máster acupuntura Campus Docent Sant Joan de
Déu
Objective: The study hypothesis is to assess whether a microbloodletting in left MC9 (ZhongChong) is effective in lowering high bloodpressure figures, at the time of the visit.
Material and Methods:
To this end, a research project is carried out with a pseudorandomised intervention of 30 patients who attended the Primary Medical Care Centre in Pallejà, with blood pressure figures between 140179/90-109 mmHg. They were assigned alternately and consecutively
in three study groups A, B and C, each group with an n of 10.
Group A: Microbloodletting of 5 drops of blood was performed onleft MC9(located in the most prominent area of the pulp of the 3rd finger ofthe left hand);Group B: Microbloodletting of 5 drops of blood was performed on
Shi Xuan of the fourth finger of the left hand to compare whether thepuncture and microbloodletting at another point, of similar location,
has an effect on blood pressure;Group C: No intervention was performed, only 10-minute rest as inall the groups under study.
Results:
It is observed that there is a statistically significant decrease in systolic blood pressure in patients in group A (left MC9), compared to theother two groups B and C (p=0.006).
In group A, systolic blood pressure is reduced by 18.6 mmHg on average. In contrast, both in group B and C, the decrease in systolic bloodpressure is 10.8 mmHg on average.
Conclusions:
It can be affirmed that performing a microbloodletting of 5 dropsof blood in MC9 on the left side is effective to lower systolic bloodpressure in patients with BP figures between 140-179/90-109 mmHg,
with a statistically significant difference (p=0.006).

Correspondence to:Patricia Natalia Dolcet Romeo
E-mail: pdolcet@hotmail.com

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BOOK OF ABSTRACTS | 12th European Congress of Integrative Medicine · 1st International Symposium on Integrative Health and Education

Title: Acupuncture and Moxibustion treatment for cervical ripening
Chiara Capece1, Patricia Natalia Dolcet Romeo1
1
Máster acupuntura Campus Docent Sant Joan de
Déu
Objectives:
Main objective: to evaluate the efficacy and safety of acupuncture
and moxibustion treatment at Ho Kou (IG4), Taé Tsong (H3), San In
Tsiao (BP6) and Zhinyin (V67) points, in pregnant women who have an
unfavourable Bishop test from of 39 W.
Secondary objective: evaluate the incidence of spontaneous onset
labour and pharmacological inductions at delivery (Propess).
Material and method:
Descriptive study of intervention in 84 pregnant women (64 nulliparous and 20 multiparous) aged> 18 and <45, of low or medium
obstetric risk, between 39 and 41 + 6 W, who attended the ACMAD
consultation of the Hospital “Sant Joan de Déu” in Esplugues de Llobregat with a Bishop test < to 6. A posteriori, we investigated the clinical histories of the patients, assessing: number of inductions, type ofdelivery, gestational age (W), baby weight, sex and Apgar test.
Discussion
Sterile stainless steel needles were inserted into points IG4, H3, BP6
bilaterally, and moxibustion was performed in V67 for approximately
15 minutes between 1 and up to 4 sessions with frequency twice a
week.
Results
71.4% of women did not have to undergo pharmacological induction at delivery. 56% achieved an eutocic delivery, 20.2% instrumented deliveries and 23.8% caesarean section.
There was significant statistical dependence (p = 0.007) between
pharmacologically induced deliveries and caesarean sections; andacupuncture and eutocic births. The relationship (p=0.008) between
parity and Propess was also observed: induction was more frequentin nulliparous (35.9%) than in multiparous (5%).
Conclusions
Treatment with Acupuncture and Moxibustion for cervical ripening
is effective and safe to reduce the number of pharmacological inductions at birth and the incidence of caesarean section.

Correspondence to:
Chiara Capece
E-mail: chiaracomadrona@gmail.com

Title: Acupuncture as a treatment inbreastfeeding problems
Raquel Pérez Guervos1, Patricia Natalia Dolcet Romeo1
1
Máster acupuntura Campus Docent Sant Joan de
Déu
Breastfeeding (BF) is the ideal way to provide young children with
the nutrients they need for healthy growth and development. The
World Health Organisation (WHO) recommends exclusive BF until thefirst 6 months of life and that, at this age, weaning is carried out gradually, so that breastfeeding is maintained for a time not less than 2
years.
Breastfeeding problems such as mastitis, obstructions and/or cracks can lead to early abandonment of breastfeeding.
Objectives: To evaluate acupuncture treatment in affected women,
to select the appropriate treatment and to assess its effectiveness.
Method: a clinical sample of five women is performed. The sample
is collected from October to December 2014. A medical history, breast
examination, pulses and tongue and assessment of the consumption
is carried out. Individual energy diagnosis is performed and acupuncture points are selected. The average number of visits was 3 sessions.
Results: The common symptomatology is breastfeeding pain as wellas tiredness, frequent awakening, irritability and nervousness. Difficulty in family relationships and little support for breastfeeding could
be highlighted. Therefore the energy diagnosis was similar. The treatment was aimed at the reduction of symptoms and the resolution ofproblems.
Conclusions: Acupuncture is an effective tool in the resolutionof mastitis, breast obstructions and/or cracks. The rapid remissionof symptoms is surprising, in addition, they feel calmer and safer inraising their children. Research paths should be opened with clinical
trials to demonstrate its effectiveness in the scientific community.

Correspondence to:Raquel Pérez Guervos
E-mail: raquelguervos@gmail.com

BOOK OF ABSTRACTS | 12th European Congress of Integrative Medicine · 1st International Symposium on Integrative Health and Education

Title: A pilot study of standardization in
the English translation of traditional Korean medicine prescription terminology
Youme Ko , Chan-Yong Jeon , In-Sik Han , Jin-Moo
Lee1, Jun-Bok Jang1, Seung-Ho Sun3
1
Kyung Hee University
2
Gachon University
3
Sangji University
1

2

3

Objectives: To explore the current state of standardization in the
English translation of traditional Korean medicine(TKM) prescription
terminology in domestic and international scientific journals
Material and method: We searched PubMed, Oriental Medicine
Advanced Searching Integrated System(Oasis), National Digital Science Library(NDSL) in May 2019 for all published reviews on representative prescription of traditional Korean medicine, Ojeok-san. No
restrictions on language and search period. First, we searched the
Korean databases with the search term, and list up the English translation terms on in included Korean studies. Then, develop the searchstrategy of English publications on in Pubmed.
Analysis: We used the frequency analysis to figure out various English translation terminology of Ojeok-san and compare the similarity
with Korean Pharmacopoeia(KP) and OASIS - decoction part.
Results: Forty-two studies met the inclusion criteria. We found outthat there were seven different types to translation version of termson Ojeok-san in included studies. Fourteen studies used the OASIS
version of English translation term and none were applied KP version.
Discussion: Currently, there are several English terminology references on traditional medicine, such as International Standard Chinese-English Basic Nomenclature of Chinese Medicine in China, Standards of Reporting Kampo Products(STORK) in Japan, etc.. Although,there were few studies on standardization of TKM terminologies in
Korea, but still no proper references on TKM English translations weredeveloped. Therefore, unified English terminologies on TKM shouldbe needed for introducing the superiority of TKM in worldwide.
Conclusions: The standardizations on TKM terminologies should bethoroughly developed and it will help to show the superiority of TKM.
We hope this result could be used as a meaningful reference for thedevelopment of future standard guideline of TKM English translation
terminology.

Correspondence to:Youme Ko
E-mail: iseeymk@gmail.com

111

Title: Integrative Nursing in clinical practice
Laia Masllorens de la Rosa1, Susana Rodríguez
López11
ISIC-Institut de Medicina Integrativa i Conscient
Background:
Integrative nursing represents a new approach to patient care andaccompaniment. This approach draws on humanistic models and gives the person his multidimensional and interdependent conception.
It places the patient at the centre of care provision - the patient
becomes actively responsible for their life process and also takes into
account the importance of the care of the space in which the clinicalpractice develops and the self-care and self-preparation of the professional that establishes a therapeutic relationship with them.
The professional, in addition to being technically trained, must be
trained with other skills, which the humanist approach gives to theprofession.
Objectives:
To define integrative nursing and the pillars on which it is based.
Description of the problem. Material and method:
We understand that a new paradigm for the human being, such as
the one that defines integrative medicine, also needs a new paradigm
that draws a new approach in the way of caring, that integrates thehuman being, the environment in which they live and/or develop andtheir relationships.
Results and discussion:
Integrative nursing describes a new way of considering care plans
and raises the possibility of applying them in any field of work.
Conclusions:Integrative nursing in clinical practice responds to the need fornurses to adapt to the change in the medical paradigm that we areleading and likewise, it is an applicable model in the different fields
that coexist.
Bibliography:
Master’s Degree in Medicine and Naturist Nursing. Barcelona 2011.
Conference on death. Barcelona 2018.
Course of spiritual accompaniment in the process of dying. Vinyana
Association 2016.

Correspondence to:Laia Masllorens de la Rosa
E-mail: l.masllorens@isic-bcn.com

112

BOOK OF ABSTRACTS | 12th European Congress of Integrative Medicine · 1st International Symposium on Integrative Health and Education

Title: Generalized Tetanus: Successful
Outcome When An Integrative Approach
Is Incorporated
Marisol Estrems Membrado1, Vicente Gil Gómez1
1Clínica Bayés, Vic, Barcelona, Spain.
1Hospital de Viladecans, Viladecans, Barcelona,
Spain.
A healthy 65-year-old caucasian woman sustained a stab wound
above her left ankle from a piece of cane. The patient was admitted
into hospital with a presumed diagnosis of a wound infection. Treatment with amoxicillin-clavulanic acid was initiated. The wound was
debrided under local anesthesia two days after admission. Cramps
became increasingly severe over the next 36 hours with spastic equino deformity of foot. The patient worsened with hyperexcitability totouch when wound was cleaned and dressed, bilateral spasms in both
lower extremities to tactile stimulus, dysphagia and some desaturation episodes that required traqueostomy for mechanical ventilation on day 8. Clostridium tetani was isolated from the wound and a
new surgery was required for wide debridement or amputation. At
this point the patient was under treatment with midazolam, cisatracurio and bolus of atracurium during the change of dressings, thenhomeopathic treatment with Hypericum 30 ch and Nux Vomica 9 ch
and Ledum Palustre 200 ch was given prior and after the surgery. Decompression fasciotomy and exeresis of peroneus longus, peroneus
brevis and tibialis anterior muscles was performed on day 15. Cisatracurio was stopped the next day. She needed only the bolus of atracurium during the change of dressings. The patient exhibited clinicalimprovement the next postop 48h with a small aggravation (day 19)
when wound was cleaned. On day 18 atracurium was not needed. On
day 19 atracurium was given and then stopped definitely. The patient
exhibited clinical improvement and she was extubated on day 30 anddischarged to home on day 45 in good health.
Written informed consent from the patient was obtained for
publication.
Acknowledgements
The author wishes to thank nurses Maribel Sánchez and Maribel
Corral for their unconditional support, Dr. Assumpta Mestre, friend
and professor, for advice on homeopathy.

Correspondence to:Marisol Estrems Membrado
E-mail: draestrems@gmail.com

Title: The dance of electrons, the forgotten
key to metabolism
Ana Maria Oliva Brañas1
1Profesional libre, Benidorm, AlicanteIntroduction: Every atom is essentially formed by positive electriccharges (protons) and negative charges (electrons). REDOX reactions
are the classic example of electron exchange between two atoms. Allbiochemistry can be rewritten in electromagnetic code. When we understand physiological processes from an electromagnetic view, concepts are greatly simplified, and other possibilities emerge.
Method and results: The formation of ATP through the Krebs cycle
is conditioned by the existence of an electron pool in so-called cellularrespiration. The different stages of the cycle are based on the exchange of electrons and protons, where electrons pass from higher energy
states to lower energy states, from one atom to another, in a relentlessdance that allows life to occur. The contribution of these electrons,
and the coherence in the endogenous electromagnetic radiation thengo from being a metabolic by-product to be turned into somethingwith which it is possible to interact. When instead of thinking about abiochemical code (with a myriad of different compounds) we introduce electromagnetic concepts, we find a great variety of diagnostic andtherapeutic possibilities that are still very minor and not sufficiently
explored. Certainly, only some areas of medicine use electromagnetic
technologies, widely known for their effects on aesthetics or physiotherapy. That is just the tip of the iceberg of an emerging field thatneeds to be understood from every possible angle.
Conclusion: An electromagnetic view of health and life in generalallows us to understand new keys to health, with both diagnostic andtherapeutic applications of great value. The great advantage is thatelectromagnetic concepts are very simple to apply, have no unwanted
effects and act on the system as a whole, strengthening the body’s
own capacity for self-regulation.

Correspondence to:
Ana Maria Oliva Brañas
E-mail: hola@anamariaoliva.es

113

ORAL
COMMUNICATIONSBOOK OF ABSTRACTS | 12th European Congress of Integrative Medicine · 1st International Symposium on Integrative Health and Education

Title: Mindfulness as a Tool in Primary
Care

Margarita Villar Fidalgo1, Cristina Serrano Quiles2
1
Atencion Primaria. Sermas
2Instituto de Técnicas Holísticas, Qi

114

BOOK OF ABSTRACTS | 12th European Congress of Integrative Medicine · 1st International Symposium on Integrative Health and Education

Title: Role of Potassium (K) in Reducing
Joint Pain in Rheumatoid Arthritis (RA):A Randomized Controlled Study of K Enriched Vegetarian Diet In Patients on Standard Care
Toktam Kianifard1, Manjit Saluja2, Arvind Chopra2
1Rheumatology Research Centre, Tehran University of Medical Sciences, Islamic Republic of Iran
2Center For Rheumatic Diseases
Objectives: to evaluate the therapeutic role of potassium (K) in RA
Material and Methods: 172 consenting symptomatic active disease
patients (American College Rheumatology/ACR 1988 classified; mean
age 48 years, 89% women, 76% seropositive rheumatoid factor, meandisease duration 9 years) were randomized as per protocol into a 16
week study [Registered CTR India/2015/05/008963] into 3 arms- K
rich diet (Arm A; 3 gm K daily), K rich diet plus K food supplement[Arm B ; 7 gm K daily) and routine diet (Arm C: 2 gm K daily). Patients
continued supervised medication (72% methotrexate, 27% steroids)
and vegetarian diet; monitored as per protocol . Standardized K foodsupplement contained a mixture of selected pulses and spices andK salt [ 4 gm elemental K per 100 gm]. Standardized food frequency
questionnaire recorded diet.
Analysis: By (i) Indian Government food composition guidelines (ii)standard efficacy and toxicity measures/ indices (ACR) (iii) Standard
statistical analysis (ANOVA); significant p<0.05
Results: Baseline intake of K was low. 155 patients (90.1%) completed. Adverse events were mild; none withdrawal. Overall, patients
improved substantially. Arm B (high K intake) showed significantly
reduced pain (visual analogue scale; p=0.03) and improved function(Health Assessment Questionnaire, p=0.05). K intervention was a significant predictor for pain relief (Odds Ratio 1.13, 5.27). Dietary compliance/recall were important concerns.
Discussion: RA is a difficult-to-treat disorder and diet is sparsely included in the current management guidelines (ACR, European). Low
K intake is reported (RA). K, a critical micronutrient in health, is poorly
researched (RA). Vegetables/fruits provide K and have several otherpotential benefits. This preliminary study focuses on role of food based K in treating RA. Conclusions: This true-to- life controlled study demonstrated a clinically beneficial adjunct role of increased food based
K intake in RA patients on standard modern therapy.

Correspondence to:Toktam Kianifard
E-mail: toktam_kiani81@yahoo.com

Title: Four-year long-term effects of aMultimodal and combined Multimodal-Aerobic Therapy in Breast Cancer Survivors with Cancer-Related Fatigue (CRF)
on hygio- and salutogenic measures andtheir impact on CRF – results of a comprehensive cohort design study
Matthias Kröz1, Falk Quittel2, Marcus Reif3, Annette Mehl2, Christoph Gutenbrunner4, Arndt
Büssing5
1Department of Internal Medicine, Havelhöhe
Hospital, Berlin, Germany; Research Institute Havelhöhe, Berlin, Germany; Institute for Social Medicine, Epidemiology and Health Economics, Charité– Universitätsmedizin Berlin, Berlin, Germany; Insti
2Research Institute Havelhöhe, Berlin,Germany
3Society for Clinical Research, Berlin,Germany
4Clinic for Rehabilitative Medicine, Hannover Medical School, Hannover, Germany
5Institute for Integrative Medicine, University ofWitten/Herdecke, Herdecke, Germany

Objectives: Cancer-related fatigue (CRF) and cancer-related insomnia
are frequent symptoms in breast cancer survivors (BC). Evidence-based
therapeutic approaches besides aerobic-training (AT) include sleep-education/restriction (SE), psycho-education (PE) and mindfulness-oriented therapies. A 10-week multimodal-intervention (MT) including SE,
PE, eurythmy- and painting therapy, or MT combined with AT (CT) werecompared to AT, respectively. We report the long-term effects on hygio-/salutogenic measures (autonomic regulation (aR), self-regulation(SRS), internal coherence (ICS)) and evaluate the predictive impact ofthese scales onCRF.
Methods: In this comprehensive cohort design study BC with chronic
CRF were randomized or allocated by patient preference to one of thetherapy arms. AR, SRS, ICS, Cancer Fatigue Scale (CFS-D) were measured
after 10 weeks of intervention (T1), 6 months later (T2) and after 4 years(T3). Statistical analysis used multivariate, propensity-score adjusted regression modeling.
Results: 126 BC were included (65 randomized, 61 allocated by preference). Compared to AT, CT and MT were superior regarding SRS at T1/
T2 or just at T1, respectively, with high SRS-levels persisting after 4 years.
ICS was superior for both CT and MT at T2 and T3 (all p<0.05). AR improved from baseline in MT and CT without showing statistical superiority
to AT, yet its rest/activity subscale was superior at T2 in MT (p<0.05).
In multivariate regression analyses baseline AR and ICS were predictors
for CFS-D after 6 months (aR: ß=-0.41, ICS: ß=-0.36; all p<0.05), whereas end-of-intervention aR was the only 4-year long-term predictor for
CFS-D (ß=- 0.54; p<0.01).
Conclusion: In this study a multimodal and a multimodal-aerobic
CRF-treatment were immediately or 6 months later superior to aerobic training in improving self-regulation and after 6 months rest/activity
regulation and internal coherence, respectively, which remained sustainable even after 4 years. Autonomic regulation and ICS were baseline
predictors for CRF after 6 months, while aR was the only long-term predictor.
Correspondence to: Matthias Kröz
E-mail: mkroez@havelhoehe.de

BOOK OF ABSTRACTS | 12th European Congress of Integrative Medicine · 1st International Symposium on Integrative Health and Education

Title: Prolonged overall survival in patients with metastasized non-small celllung carcinoma after combined treatmentof adjuvant chemotherapy and Viscum
album L. versus chemotherapy alone, amulticentre real-world data analysis
Friedemann Schad1, Anja Thronicke2, Megan
Steele3, Burkhard Matthes1, Christian Grah4, Harald Matthes5
1Hospital Havelhöhe, Interdisciplinary Oncology
and Palliative Care, Berlin, Germany
2Research Institute Havelhöhe, Berlin, Germany
3Institute of Health and Biomedical Innovation,
Queensland University of Technology, Brisbane,
Australia
4Hospital Havelhöhe, Lung Cancer Center and Department of Pneumology, Berlin, Germany 5Institute for Social Medicine, Epidemiology and Health
Economics, Charité - Universitätsmedizin Berlin,
Berlin,Germany
Background: Stage IV non-small cell lung carcinoma (NSCLC) is oneof the most devastating diagnoses worldwide. Mistletoe therapy (Viscum album L., VA) has effectively been applied as an add-on treatment within integrative oncological concepts to improve quality oflife. Overall, there is little evidence for add-on VA on survival of cancer
patients. However, recent results suggest a beneficial effect [1, 2]. A
multicentre observational health services research study was conducted to compare the combination of chemotherapy and VA (CVA)
versus chemotherapy (C) for patients with metastasized NSCLC. The
primary outcome was the assessment of overall survival.
Methods: Patients with stage IV NSCLC living at least 4 weeks
post-diagnosis were non-randomly assigned to groups C (chemotherapy) or CVA (chemotherapy and Viscum album L.). Demographic, diagnosis-, histology- and treatment-related data were retrieved
from the network oncology, a clinical cancer registry for health services research (register ID: DRKS00013335). Written informed consent
from patients has been obtained prior enrolment; the study has been
approved by the ethics committee of the Medical Association Berlin(Eth-27/10).
Results: A total of 158 eligible patients between February 2010 andJune 2016 were enrolled. The median OS was 8.0 months for group
C patients and 17.0 months for CVA patients (Hazard ratio - HR: 0.52,
95% CI, 0.33 - 0.83; P = .007; adjusted HR: 0.44, 95% CI, 0.26-0.74, p =.002). One-year
survival rates for C and CVA were 35.5% and 60.2%, three year survival rates were 14.2% and 25.7%, respectively.
Conclusions: The results of the present health services researchanalysis reveal that the survival is significantly prolonged in patientswith metastasized NSCLC treated with a combination of adjuvant chemotherapy and VA.
Bibliography:
Troger W, et al. Eur J Cancer.2013;49:3788-3797
Axtner J, et al. Schad F. BMC Cancer.2016;16:579

Correspondence to:FriedemannSchadE-mail: fschad@havelhoehe.de

115

Title: Herbal Formula improves upperand lower gastrointestinal symptoms:
The Gut Relief Study
Karin Ried1, Ranjini Dorairaj1, Nikolaj Travica1,
Avni Sali1
1National Institute of Integrative Medicine (NIIM),
Melbourne, Australia
Objectives
To investigate the tolerability and effectiveness of the Gut-Relief-Formula on gastrointestinal disturbances in Australian adults in asingle-arm pre-post dose-response study of 16-weeks duration.
Background
Gastrointestinal (GI) problems affect half of Western populations.
Symptoms can vary from frequent reflux to irritable-bowel-syndrome(IBS). The Nutrition-Care-Gut-Relief-Formula contains a combinationof herbs and nutrients including curcumin, aloe-vera, slippery-elm,guar-gum, pectin, peppermint-oil and glucosamine, shown to benefit
the gastrointestinal-system.
Methods
A total of 43 participants with gastrointestinal symptoms completed the study. We used a series of validated questionnaires, including
the Leeds-Dyspepsia-Questionnaire, Bristol-Stool-Chart, Birmingham-IBS-Symptom-Questionnaire, and assessed gut-microbiota,
and intestinal- permeability. After a run-in-phase, participants were
provided with 5g/day, followed by 10g/day, or a choice of either
0g-5g-10g/day of the formula for 4-weeks each.
Results
The Gut-Relief-Formula significantly improved the frequency andseverity of upper and lower GI- symptoms by 60-80%, including indigestion, heartburn, nausea, or constipation, diarrhea, abdominal
pain, troublesome flatulence, as well as mouth-ulcers, bad-breath,rashes, improving quality of life and sleep.
All participants with normal stool, 90% with hard stool, and 66%
with soft stool recovered from intestinal-permeability, evident by normal Lactulose/Mannitol-Ratios.
The Gut-Relief-Formula generally improved microbial profile inparticipants with normal or hard stool, with a marked increase in
Lactobacillus, Clostridium, Bacterioides-vulgatus, and Faecalibacterium-prausnitzii.
Almost half of the participants with upper GI-symptoms taking proton-pump-inhibitors (PPI) for heartburn, no longer required PPIs at
the end of the study.
A third of participants reintroduced food triggers, such as FODMAPs, garlic, onion, beans, and cruciferous vegetables, or reflux causing acidic/spicy foods, e.g. citrus, tomato, caffeine, curry in their dietat the end of the 3-month study, without symptom aggravation.
Conclusions
The herbal Gut-Relief-Formula significantly improved gastrointestinal symptoms over 3-months, while reducing intestinal permeability,
and improving microbial profile, reducing the need for reflux medication, and enabling the consumption of previous food triggers.
Correspondence to:
Karin Ried
E-mail: karinried@niim.com.au

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Title: Repeatability & responsiveness of
the warwick holistic health questionnaire
Nicola Brough1, Simon Saldanha1, Ponninbaduge
Perera1, Sarah Stewart-Brown1 1University of
Warwick
Introduction
Patient reported outcome measures are essential to health careevaluation. Repeatability and responsiveness (at group and individual level) are key psychometric properties of PROMs essential to assessment of impact. We measured these properties for the 25-item
Warwick Holistic Health Questionnaire (WHHQ) developed to evaluate craniosacral therapy (1).
Methods
Repeatability: Online version of WHHQ created using Qualtrics software. Sample of 109 completed WHHQ twice, 2-week interval without intervention. Anchor question assessed change in health status.
Paired t test for change and Pearson’s correlation coefficient for participants who had no change in their health were calculated.
Responsiveness: 146 participants completed the WHHQ before andafter therapy; Distributional methods used to assess responsiveness.
Cronbach’s alpha and paired t test for change were calculated.
Results
Repeatability: No significant change over two weeks (p=0.752).
Pearson’s correlation coefficients were high for all participants (0.832;
p < 0.001) and for those (n= 78) showing no change in health status(0.822; p < 0.001).
Responsiveness: Cronbach’s alpha = 0.84; mean change score,
5.31(SD=10.01); effect size= 0.46. Standardized Response Mean=53(p=0.7019); Standard Error of Measurement (SEM)= 4.92.
Participants with > 2.77SEM increase= 16.4% (n=24) and decrease=2.1% (n=3) respectively. 49.3% of participants improved using Cohen D effect size > 0.5.
Conclusions
Psychometrically sound PROMS are needed to evaluate complementary and alternative medicine. As well as being valid and reliable,
the WHHQ is both repeatable and responsive to change.
Part-funded by Dr Janine Leach Research Award.
(1)
Brough, Nicola (2017) The Warwick holistic health questionnaire : the development and validation of a patient-reported outcome measure for craniosacral therapy: a mixed methods study. PhD
thesis, University ofWarwick.

Correspondence to:
Nicola BroughE-mail: nicola.brough@warwick.ac.uk

Title: New Integrative Cancer Care Expert Platform in Brussels for Advancing
the Research of Comprehensive Patient
Care – Opportunities for the Future
Yannick Pots1, Madan Thangavelu2, Baro Deressa3, Christel Fontaine4 3CHU Brugmann
1VUB
2Transdisciplinary University Bangalore
4UZ Brussel
Background: Cancer is 2d major cause (9.6 m) of all deaths (56.9 m)
globally, according to WHO- Statistics 2016. With estimated impact of
USD1.16 trillion (2010) and estimated increase of 0.66%/year, cancer
will create ceteris paribus significant health and pharmaceutical costsin the future.
Aim: To integrate Ayurvedic and Conventional evidence-based Medicines in order to develop a new integrative cancer care expert platform in Brussels between Europe and India that could be the bench
for comprehensive patient care at lower costs for the future.
Method: Based on Ayurvedic classification of diseases and ICD-11
with 26 + V(Supplementary Chapter Traditional Medicine Conditions)& X(Extension) codes for diseases, we created a new 15- minor matrices/1-major matrix model in order to link both systems.
Results: We could determine that cancer, according to cancer subtypes, is a common Pitta (37.50%)/Kapha (35.42%) doshas, resp. Earth(35.42%)/Water (29.16%) sub-doshas disease. Earth- Water sub-doshas level (sd-L) cancer-subtypes (C-st)(64.58%) and Fire sd-L (C-st)(14.58%) create about 80% of all cancers. In order to decrease healthcare costs and to optimize health (status) (immaterial) values (added),
as strategy, new transdisciplinary cancer treatment at a new integrative cancer expert platform in Brussels (as capital of Europe/European
Union), with universities of health/ pharmacy/(social)health sciencesof both continents Europe and India is mandatory. Care with emphasis on hygiene, resp. diet/ herbal remedies, breath exercises/physicaltherapy, environment protection, stress control, meaningfulness,sleep and social support, yoga, and meditation, might optimize comprehensive patient care.
Conclusion: Integrating both systems gives a broad insight into thepathophysiology of the different cancer sub-types. A new integrativecancer care expert platform in Brussels with joint (between Europe
and India) transdisciplinary cancer research could be a source for decreasing health (care) costs and optimizing health (status) (immaterial) values (added) and to optimize comprehensive patient care internationally as opportunities for the future.

Correspondence to:
Yannick Pots
E-mail: christel.fontaine@uzbrussel.beBOOK OF ABSTRACTS | 12th European Congress of Integrative Medicine · 1st International Symposium on Integrative Health and Education

Title: Beyond miracles: a qualitative studyof the healing effects of pilgrimage to
Lourdes
Emmylou Rahtz1, Sarah Goldingay2, Elizabeth
Dieppe3, Sara Warber4, Paul Dieppe1 1Universityof Exeter Medical School
2University of Exeter 3Independent 4University ofMichigan
Objectives: Pilgrims have been visiting Lourdes, France, since 1858
when a vision of the Virgin Mary appeared. Today, Lourdes hosts six
million visitors annually, many of them seeking healing. We sought tounderstand the experiences of these pilgrims: what they feel, whatchanges occur within them, and how they explain these experiences.
Material and method: In June 2017 we spent ten days carrying out
fieldwork in Lourdes: interviewing ‘malades’ – sick pilgrims– and themany volunteers and healthcare professionals who support them. We
spoke to over 60 people, amassing 33 interviews, 10 focus groups, 19participant drawings and extensive ethnographic notes.
Analysis: We collaboratively identified key concepts and themesin this rich data set, following the ‘Consolidated criteria for reporting
qualitative research’ (COREQ).
Results:
A key theme was connection and sense of community, both between volunteers and the malades they cared for, as well as bonding
between the volunteers. Some had noetic experiences, connecting tosomething beyond the self. A schoolgirl said “I came and I prayed toMary and then she touched me a lot and I felt like I was actually talking to her. And then I was compelled to come again.” Altruism wasimportant: everybody gives to everybody else and seeks self-improvement, both at Lourdes and when they return home. One woman
described “a time to reflect on how I could be different and improvemyself”. People experienced changes in how they saw and accepted
illness and in their self-perception. Lourdes offers the chance to reset
oneself.
Discussion: While many hope to be cured at Lourdes, instead they
are often healed through other enriching elements of the experience.
Conclusions: People do not visit purely in the hope of a miracle:
their motivations are more complex and diverse, and healing can beexperienced through connection, giving and self-renewal.
Correspondence to: Emmylou Rahtz
E-mail: e.rahtz@exeter.ac.uk

117

Title: Solasodine rhamnose glycosides,
review of 3 decades of clinical experience in the natural treatment of neoplastic skinlesions
Gastón Cornu Labat1, Bill E. Cham2 1Tahoma Clinic, Seattle, WA,EEUU
2Australasian Medical Research, Port Vila, Republic of Vanuatu
Objective: Review of 3 decades of clinical experience in the natural
treatment of non-melanotic neoplastic skin lesions with Solasodinerhamnosed glycosides (SRGs) in a specific ointment formulation.
Material and Method: Phase 1 to 3 clinical trials, from controlled
open-label to multicentre randomised single and double blind studies, with a total of 423 patients treating actinic keratosis, keratoacamptoms, and squamous cell basal carcinomas with formulation of
SRGs in ointment, along with over 100,000 patients worldwide postmarketing of said ointment for the same pathologies.
Analysis: Follow-ups of up to 5 years with clinical, histological andbiochemical evaluations. Results: With treatment periods from 3 days
to 12 weeks and from 2 to 10 daily applications, the data collected
demonstrate between 75 and 100% resolution of the treated lesions
depending on the duration of the treatment, frequency of application
and adherence to the recommendations. No documented systemic
adverse effects and minimal side effects such as transient pain andlocal irritation at the application site have been the only adversities
observed.
Discussion: SRGs are a group of glucoalcaloids that occur naturally
in plants of the Solanaceae family, Solanum genus, and have demonstrated a high degree of specificity and a broad spectrum against multiple types of cancers. The authors present a review of their 3 decadesof clinical experience in the effective use of SRGs in the treatment ofskin cancers and premalignant skin lesions.
Conclusions: SRGs formulated in ointment is the treatment for
non-melanotic neoplastic skin lesions with the highest cost-benefit
rate, demonstrating results superior to all other existing modalities.

Correspondence to:
Gastón Cornu Labat
E-mail: gcornulabat@gmail.com

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BOOK OF ABSTRACTS | 12th European Congress of Integrative Medicine · 1st International Symposium on Integrative Health and Education

Title: Treating uncontrolled hypertension with Hibiscus Sabdariffa when
standard treatment is insufficient: pilot
intervention
Marwah Alanbaki Alanbaki1, Renata Campos
Nogueira1, Anne-Laure Cavin1, Bertrand Graz1
1Antenna Foundation
Objectives
To assess a food product validated by several clinical trials, Hibiscus
sabdariffa (Karkade), in case of uncontrolled hypertension either withor without medication.
Background
Among >500’000 Syrian refugees in Jordan, 80% reside outside ofrefugee camps. In case of hypertension, they could benefit from using
Hibiscus sabdariffa (HS) as it is locally available, affordable, and it is themost common herbal product used against hypertension in Jordan.
Material and methods
In a multicentric, pilot clinical study, participants with blood pressure (BP) above 140/90 mmHg were encouraged to drink Karkade tea
containing 10g of HS/0.5L daily. If during the second and third week
BP was still high, this dosage was increased to 15g of HS/1L and to 20gof HS/1L. Results
Among 38 Syrian refugees living outside the refugee camps, 29 participants finished the program. 75% were already taking antihypertensive medication but theire hypertension was uncontrolled; 28%
used no medication. Based on the weekly measurement of bloodpressure, improvements were observed after the first week of Karkade tea consumption.
HS was generally well tolerated (except 3 patients with mild symptoms, possibly related to other medications as well), and 38% of theparticipants have reached the target blood pressure at the end of thissurvey.
Discussion
This study assessed the feasibility of a program supplying a foodproduct, Hibiscus sabdariffa (Karkade) as adjuvant in the treatment ofhypertension. For the first time in the literature a large proportion ofparticipants (75%) used ongoing standard hypertensive medication.
Conclusion
Hibiscus sabdariffa (Karkade) is generally well-tolerated and appears
to be helpful to treat uncontrolled hypertension whether or not usedwith standard medication.
Bibliography
2. High Blood Pressure | National Heart, Lung, and Blood Institute(NHLBI) [Internet]. Nhlbi.nih.gov. 2019 [cited 13 May 2019]. Available
from: https://www.nhlbi.nih.gov/health-topics/high-blood-pressure
Correspondence to: Marwah AlanbakiAlanbaki
E-mail: malanbaki@antenna.ch

Title: Biomedical approach inautism spectrum disorders – theimportance of assessing inflammation
Tatjana Mijatovic1, Dario Siniscalco2, Krishnamurthy Subramanian3, Eugene Bosmans1, Kenny De
Meirleir4, Vincent Lombardi3
1R.E.D. Laboratories; Z.1 Researchpark 100,
B-1731 Zellik, Belgium
2Department of Experimental Medicine, University of Campania; 80138 Napoli, Italy 3Nevada
Center for Biomedical Research, Reno, NV, 895570552, USA 4Himmunitas vzw, 1120 Brussels,Belgium
Background: Published findings have identified widespread changes in the immune systems of children with autism spectrum disorders (ASD) suggesting that autism may, in fact, be a systemic disorderwith connections to abnormal immune responses. Evaluating autism
is hindered by a lack of specific biomarkers, making these pathologies
difficult to diagnose.
Methods: As part of the respective patient’s biomedical assessment, samples from ASD-diagnosed patients were analyzed by R.E.D.
Laboratories (Zellik, Belgium) The present study represents a retrospective investigation of existing clinical data. A total of 42 available
files were surveyed.
Results and Discussion: The vast majority of patients tested show anotable increase in inflammation-related markers: 86.5% presented
with elevated IL-8, 71% with elevated PGE2, 57% with elevated MCP1, 47% with elevated IL-1β, and 41% with elevated elastase while 68%
displayed an abnormal expression of sIgA in the stool. Overall, the fecal flora of autistic children tends to be perturbed when comparedto the fecal flora of healthy children. Our data suggest the diversity
index was low in 85% of cases and 39% presented with high Bacteroides while the increase of Streptococcus could be correlated with theworsening of cognitive abilities and aggressive behavior. The very highprevalence of increased inflammation-related markers is most probably the end result of several dysfunctions in ASD patients, as already reported in previous studies. Among them, a large number point
towards intestinal dysfunctions (including gut dysbiosis and leaky gut)
and chronic infections (including intracellular pathogens and tick-borne infections). This hypothesis is further supported by the very highpercentage (84%) of patients with increased serum soluble CD14.
Conclusion: Our results, in conjunction with previous reports, clearly point towards the importance of an integrative approach involving the assessment of the inflammation-related biomarkers in ASD
patients. A larger investigation is needed to further define the mostuseful biomarkers.
Correspondence to:Tatjana Mijatovic
E-mail: tmijatovic@redlabs.beBOOK OF ABSTRACTS | 12th European Congress of Integrative Medicine · 1st International Symposium on Integrative Health and Education

119

Title: Integrative treatment of community
acquired pneumonia (CAP) without antibiotics

Title: Dyadic Integrative Exercise for Persons with Dementia and their Care Partners

Ulrich Geyer1, Kathrin Nusser2, Sebastian Appelbaum3, Thomas Ostermann3, Andreas Laubersheimer1, Klaus Kramer2
1Department of Homeotherapy, Heidenheim Hospital, Teaching Hospital of the University of Ulm
2Department of Integrative Medicine, University
Ulm
3Department of Psychology and Psychotherapy of
Universität Witten/Herdecke

Wolf Mehling1, Travis M. Scott2, James Duffy1,
Rachel Whitmer3, Margaret Chesney1, Deborah
E. Barnes1
1University of California San Francisco
2San Francisco Veterans Affairs Health Care System
3Kaiser Permanente Northern California, Divisionof Research, Oakland, CA

The aim of the presented study was to evaluate feasibility, security
and effectiveness of integrative treatment of CAP.
Methods: Patients with radiolocigal confirmed diagnosis of CAP
were retrospectively evaluated regarding pneumonia severity score
CRB 65, inflammation parameters such as leukocytes, CRP, admission
to intensive care unit (ICU), lethality, and rate of recurrent pneumonia
comparing conventional with integrative treatment, in this study anthroposophic medicine (AM).
Results: 225 patients with CAP were evaluated – 101 with integrative treatment (IM) and 124 with conventional treatment (CM). 15/101
patients (14,85%) with IM were treated in addition with antibiotics(IM+AB) while 86/101 (86,15%) were treated with IM only and without antibiotics (IM- AB). All 124 (100%) CM-Patients were treatedwith antibiotics.
The two collectives (CM & IM) showed significant difference regarding age (CM: 75,1 years versus IM: 59,0 years; p-Wert <0,001) and severity of pneumonia (mild pneumonia: CRB-65 (1) 16,1% CM vs 46,5%
IM; p<0,001, while in moderate or severe pneumonia: CRB-65 (2+3)
83,9% CM vs 53,5% IM; p<0,001). In both treatment collectives (CM &IM), significant reduction of inflammation parameters was observed
while no significant difference regarding CRP-regression was observed
between the two collectives, as well as no significant difference wasobserved regarding lethality.
However, CM patients showed a significant higher rate of recurrent pneumonia compared to integrative treatment (29,83% versus
12,87%, p=0,0016). With respect to heterogeneity regarding age andpneumonia severity score, subgroup analysis revealed decreased
pneumonia recurrence rate in patients treated with IM with focus onelderly (p<0,0016) and patients with severe pneumonia (p<0,0016).
Therefore, we conclude, that in certain patients with CAP integrative medical treatment may be feasible, secure and effective, even
without application of antibiotics. This is of outmost relevance within
the context of antibiotic resistance. Moreover, our data document
significant reduction of pneumonia recurrence rate due to integrative
treatment (IM).
Correspondence to:Ulrich Geyer
E-mail: geyerul@gmail.com

Objectives: In the absence of disease modifying treatments for dementia, non-pharmacological interventions are vital for enhancing
the lives of persons with dementia (PWD). The Paired Preventing
Loss of Independence through Exercise (PLIÉ) study is examining theeffects of a unique integrative group movement program that targets
preserved abilities and neural mechanisms in PWD and includes theircare partners (CP). The intervention includes 1-hour community-based classes with 5 dyads, 2 days/week for 12 weeks and three monthly
home visits. We present results from a randomized controlled study
examining feasibility, efficacy and satisfaction.
Methods: Seniors with mild to moderate dementia and their CPs
were enrolled and randomized to receive either an immediate or delayed start to the Paired PLIÉ program with outcomes measured atbaseline, 12 weeks, and 24 weeks and anonymous evaluation surveys
sent after withdrawal or completion. Feasibility was assessed basedon enrollment and percent completion. Efficacy was assessed by calculating standardized effect sizes comparing change during Paired
PLIÉ vs change during control period (difference-in-differences). Satisfaction was assessed based on quantitative and qualitative evaluation
survey responses.
Analysis: Mixed effects models and descriptive thematic analysis.
Results: 30 dyads (60 participants) enrolled and 24 (80%) completed the study. Effect sizes suggested improvements during Paired PLIÉ
for PWD depressive symptoms (Cohen’s d=0.27) and PWD quality oflife (caregiver-rated, d=0.28; participant-rated, d=0.22). Satisfaction
was high (mean 1-5 Likert scale: 4.8), and participants were likely torecommend the program to others (mean 0-10 Likert scale: 9.4). Most
caregivers reported observing physical, emotional, and social benefits
for their loved ones and themselves.
Discussion/Conclusion: Paired PLIÉ is a promising integrative group
movement program for PWD and their CPs that appears to be feasible
and is associated with high levels of satisfaction and preliminary evidence of benefits to participant and care partner physical, emotional,
and social well- being.

Correspondence to:
Wolf Mehling
E-mail: Wolf.Mehling@ucsf.edu

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Title: Plasma Vitamin C Concentrations
and Cognition: A Cross-sectional Study
Nikolaj Travica1, Karin Ried2, Andrew Pipingas1,
Avni Sali2, Irene Hudson1, Andrew Scholey1
1Swinburne University of Technology
2National Institute of Integrative Medicine
Background
Vitamin C is a water soluble molecule that humans have lost theability to produce. Despite this, the vitamin’s vital biological roles havebeen well established, ranging from collagen and carnitine production, to white blood cell protection and immune stability. Literature
indicates that the vitamin plays a role in CNS functions such as neuronal differentiation, maturation, myelin formation and modulation of
the catecholinergic systems.
Objectives
Based on our recent systematic review, further research is neededthat utilizes plasma vitamin C concentrations and sensitive cognitive
assessments that are suitable for cognitively intact adults. Materialand Method
A cross-sectional trial was conducted on a number of healthy adultsamples (n = 80, age range: 24- 96 years) likely to be displaying a range of plasma vitamin C concentrations. Cognitive assessments included The Swinburne University Computerised Cognitive Assessment
Battery (SUCCAB) and the pen and paper tests, including the Symbol
Digits Modalities Test (SDMT) and Hopkins Verbal Learning Test - Revised (HVLT-R). Following cognitive assessments, blood samples weretaken and plasma vitamin C, with serum vitamin B12 (secondary measure) were measured. Nutritional intake of these vitamins was also
assessed through food frequency questionaries.
Discussion
An analysis of covariance revealed significantly higher scores on total recall, delayed recall and recognition in the adequate group on the
HVLT-R and scores on the SDMT. Additionally, an ANCOVA revealed
significantly higher performance on choice reaction time (decision
speed) and the congruent stroop (inhibition cognition) in the adequate group. A plateau in cognition with concentrations >70 μmol/L
supports the homeostatic mechanism of vitamin C in the central nervous system.
Conclusion
The present cross-sectional study revealed significantly greater cognitive performances in those displaying adequate plasma vitamin C
concentrations. Cognitive tasks included those assessing total recall,delayed recall, recognition, decision speed and inhibition.

Correspondence to:
Nikolaj Travica
E-mail: nikolaj_travica@hotmail.com

Title: Living with chronic pain - an existential and molecular perspective following integrative health care provision
Linn Rönne-Petersen1, Maria Niemi2, Harald
Walach3, Torkel Falkenberg4
1Department of Neurobiology, Care Sciences andSociety | Division of Nursing Karolinska Institutet
2Department of Public Health Science, Karolinska
Institutet
3Department Psychologie der Universität Witten-Herdecke, Germany
4Department of Neurobiology, Care Sciences andSociety | Division of Nursing Karolinska Institutet& Center for Social Sustainability, Karolinska Institutet
Patients suffering from chronic widespread pain (CWP) constitutes
a great challenge for the healthcare system. CWP is often overlappingwith other symptoms such as depression, anxiety, headaches and IBS,
hence the patients display a variety of illness. These complex healthissues often are misunderstood and misinterpreted by the healthcare
system, leading to existential suffering. Recently, studies by Nobel laureate Elizabeth Blackburn have shown that healthcare that promotes
positive changes in existential dimensions also might play a crucialrole in the maintenance of our genome. Blackburn, has shown thatthe enzyme telomerase prevents genetic information from being lostin cell division, and that chronic stress and affective diseases are associated with shorter telomer length and decreased telomerase activity.
Objectives: The PhD project aim to assess changes in telomere length (TL) and telomerase activity (TA) in CWP patients, associated withdifferent types of multimodal care over time and whether changes
can be linked to validated existential outcomes such as EQ5D, HAD,
SF36, WHOQoL, FFMQ, PCS and CPAQ as well as inductive qualitative
explorations. Material and method and analysis: This is a prospective clinical observation study with two cohorts of pain patients (n=50)
with CWP received at Vidar Rehab (anthroposophical integrative care)or The Pain Center in Linköping (standard care). The study follows a
ABA-design, where each patient cohorts constitute their own control.
Different statistical tests will be used for the analysis. Results: Preliminary results will be presented for the first time at the conference.
Discussion: The project will contribute to information that can be used
to calculate sample size and power for future randomized studies for
TA and TLinvestigations.
Future results will be triangulated (data, method and theory triangulation) by combining subjective and objective results with qualitative findings wherever possible to inform future evidence based integrative health care reform.

Correspondence to:
Linn Rönne-Petersen
E-mail: linn.ronne-petersen@ki.se

BOOK OF ABSTRACTS | 12th European Congress of Integrative Medicine · 1st International Symposium on Integrative Health and Education

Title: Environmental and neurodevelopmental factors
Rebeca Mira Sánchez1, Juan Antonio Marín
Martínez1, Isabel Bellostas Escudero1 1instituto
De Ciencias Medioambientales Y Neurodesarrollo
INTRODUCTION: In recent years, from the epidemiology and environmental toxicology, there has been growing interest in environmental factors that are contributing to the increased prevalence ofneurodevelopmental disorders; in order to understand them betterand establish, as far as possible, appropriate prevention strategies.
The academic literary base in this regard is broad.
JUSTIFICATION: Environmental factors contribute to the increased
prevalence of these disorders. Identifying, preventing and treatingthem can have a positive effect in theirreduction.
OBJECTIVE:
To conduct a 2000-2019 literature review of the most relevant environmental factors associated with the prevalence of neurodevelopmental disorders.
MATERIAL: Indexed journals METHOD:
BIBLIOGRAPHIC ANALYSIS I: Endocrine disruptors and neurodevelopmental disorders. Many publications have evidenced the association
between endocrine disruptors and neurodevelopmental disorders.
BIBLIOGRAPHIC ANALYSIS II: Pesticides and neurodevelopment. Several research projects since 2000, and numerous publications showthat mild exposure to pesticides affects the Intellectual Quotient (IQ)
and foetal and childhoodneurodevelopment.
BIBLIOGRAPHIC ANALYSIS III: Air pollutants and neurodevelopment. Air pollutants contribute to the decrease in IQ and affectneurodevelopment.
BIBLIOGRAPHIC ANALYSIS IV: Heavy metals and neurodevelopment. Scientific evidence causally associates neurotoxicity of heavy
metals with neurodevelopmentaldisorders.
DISCUSSION AND CONCLUSIONS: Identifying environmental neurotoxins and minimising the exposure of pregnant women, foetuses,
babies and children, is a good strategy to reduce the prevalence ofsuch disorders.

Correspondence to:Rebeca Mira Sánchez
E-mail: rebecamira25@gmail.com

121

Title: Prostate health: inflammation, cancer and advanced cancer
Sylvie Beljanski1
1The Beljanski Foundation
OBJECTIVES: Use rigorous scientific methods to determine effectof plant extracts (Pao pereira, Rauwolfia vomitoria) on each stage ofcancer: pre-cancer (chronic inflammation), established tumors, andadvanced metastatic disease. Prostate inflammation, prostate cancer
and advanced prostate cancer were studied.
MATERIALS AND METHODS: Inflammation: BPH-1 and RPWE-1
cells for in vitro and in vivo experiments for BPH, gene expression,Western blots. Human clinical trial in men to test effect on PSA and
BPH. Cancer: LNCaP cells and MTT assay for cytotoxicity, xenografts
for in vivo studies with TUNEL staining. Advanced Cancer: PC3 (androgen independent) cells, flow cytometry, wound healing, RT-PCR,
NFKappaB binding.
ANALYSIS: Positive results from the assays were analyzed by standard statistical methods and data shown with standard deviation andt-test with P<0.05 or P<0.001.
RESULTS: Research at Columbia University Medical Center showedthat the Pao and Rauwolfia vomitoria extracts suppress growth of
prostate cancer cells and shrink prostate tumors. A clinical study demonstrated that the Pao/Rauwolfia combination lowered PSA andalleviated symptoms in men with enlarged prostates (BPH). Biochemical evidence for anti-inflammatory effects comes from research at
Nanjing University showing Pau and Rauwolfia suppress growth of
BPH cells and specifically down-regulates inflammatory response.
A second Nanjing study revealed that the Pao extract is active
against advanced prostate cancers that are insensitive to testosterone-reducing drugs. These late stage cancers are considered untreatable yet Pao acts to restrain the NFKappaB complex from promoting
tumor growth and metastasis.
DISCUSSION: The extracts are nontoxic to healthy cells and induce
no negative side effects. They are active against all types of cancer in
men and women.
CONCLUSION: The Pao and Rauwolfia plant extracts have comprehensive therapeutic potential for prostate cancer in early, mid- andadvanced stages. There is evidence that the extracts will also work in
all three stages of other types of cancer.
Correspondence to: Sylvie Beljanski
E-mail: media@beljanski.org

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BOOK OF ABSTRACTS | 12th European Congress of Integrative Medicine · 1st International Symposium on Integrative Health and Education

Title: An integrative approach for acuteperitonitis: a retrospective sutdy of 517
patients
Marisol Estrems Membrado1, Mónica Valero Sabater2, Assumpta Mestre Blabia3, Sergio
Abanades león4
1Clínica Bayés, Vic, Barcelona, Spain
2Hospital Royo Villanova, Zaragoza, Spain
3Centre de Medicina Biològica, Barcelona, Spain
4Instituto de Salud Integrativa y Consciente, Barcelona, Spain
Aims
To determine the impact of an integrated approach on the postoperative complications in patients operated upon secondary acuteperitonitis.
Methods
A non-randomized, retrospective, single-center clinical study of 517
consecutive patients operated on for community-acquired secondary
peritonitis admitted as surgical emergencies from 1994 to 2004. An
integrated approach (Homeopathy and Bach Flowers Remedies plus
standard care) was given to 84 patients (Group IA) whereas standard
care alone was provided to the remaining 433 patients (Group SC).
Standard care included surgical management, broad-spectrum antibiotherapy and metabolic support measures, as needed. Major andminor postoperative complications (Clavien- Dindo Classification)
were obtained from 213 patients, postoperative hospital stay andpostoperative mortality were compared between bothgroups.
Results
The distribution of main primary conditions were comparable inboth groups, and included Acute Appendicitis (44.10%), Acute Cholecystitis (15.08%), Acute Left Colon Diverticulitis (5.99%), Perforated
Peptic Ulcer (16.05%), Small Intestine perforation (3.86%), Colon perforation (5.41%) and Others (9.47%). Significant differences in majorcomplications were found between groups (12.86% IA vs 27.99% AT;
p<0.05) and postoperative hospital mortality (4.28% IA vs 13.28% AT;
p<0.05). A trend towards fewer minor postoperative complications(Clavien 0-II) was found in the SC group. Postoperative hospital staylength was significantly shorter for patients of the IA group (8.92±1.0
vs 11.98±0.6 days; P<0.001). No complications potentially related to
AT were observed.
Conclusions
Patients receiving IA had a significantly shorter postoperative staylength, major complications and mortality.
Acknowledgements
The author wishes to thank nurses Maribel Sánchez and Maribel
Corral for their unconditional support.
Correspondence to:Marisol Estrems Membrado
E-mail: draestrems@gmail.com

Title: Hepatic failure of a Breast Cancer
Patient improved by administration of
Silibinin and other adjuvants
Hugo Stuer1
1University of Antwerp Family Medicine
Case report
By urgency, an additional intervention was offered to a young
woman, since one year continuously treated for breast cancer withchemo-immuno-and endocrine therapy, evolving into life threatening
liver failure.
After 10 days bilirubin levels dropped and bodily temperature,
35.6° rose into fever.
3 Months after initiation physical condition was good. CT of theliver showed involution of the meta’s. Liver parameters and tumor
marker Ca 15.3. normalized.
Discussion
Hepatic failure is a common complication of chemotherapy. Several
adjuvants are candidate for therapy: Milk Thistle and Acetylcysteine
are well documented in intoxications, Curcuma as hepatoprotection
in alcoholic liver damage and enzymes as promising antineoplastics.
Literature reported just one similar case of hepatic failure with continuation of chemotherapy in combination with silibinin extract from
Milk Thistle.
In our case chemo was also continued. Besides the silibinins otheradjuvants were: enzymes, acetylcysteine and curcuma.
The differences between the two cases were: dose, time of response and the combinations with silibinins. The final result was similar: after initiation of adjuvants it was possible during 3 months to continue
chemotherapy, with a positive impact on liver failure, tumor marker
and quality of life. Explanations for recovery of the liver and tumor
marker rely on the opportunity to continue chemo and on intrinsic
benefits of the adjuvants.
Conclusions
In this case of life threatening liver failure 3 months of additional
adjuvants made it possible to continue chemotherapy, with positive
impact on liver failure, tumor marker and physical condition. There is
growing evidence of effectivity and safety of the described adjuvants
for therapy and prevention.
Bosch-Barrera J a.o: Silibinin administration improves hepatic failure due to extensive liver infiltration in a breast cancer patient. Anticancer Res. 2014 Aug;34(8):4323-7.
Correspondence to:Hugo Stuer
E-mail: hahohugo@skynet.be

BOOK OF ABSTRACTS | 12th European Congress of Integrative Medicine · 1st International Symposium on Integrative Health and Education

Title: Holographic analysis of the blood –a 40 years review
Adam Bigelsen1
1The Bigelsen Academy
Introduction:
Bechamp defined the “terrain” as the inner microenvironmentthat defines the real health of a person. If the terrain is unhealthy,
different microorganisms are going to grow as a consequence and asa correction mechanism. My father has dedicated 40 years to analyze
the terrain and its information, developing the holographic analysis of
the blood. This process has allowed my father to be one of the mostefficient doctors in the USA during the last century.
Method and results
Using a darkfield microscope, capillary blood is observed at 40X. Different patterns are analyzed: shape, distribution and amount of cells,
darkness of the plasma, amount and movement of the symbionts,
and also shape, colour and size of the symplasts. This collected dataand interpretation show the information about the global health ofthe person, both physical and emotional. It also gives something reallydifficult to obtain by other means: the real cause of the symptoms,
that clearly appear in the symplasts in the blood. With this method
it is possible to understand that the body works as a whole, and theunderlying interconnection among each part of the human beings.
Conclusions
The blood is living tissue that reflects clearly the homeostasis of thewhole body. The holographic analysis uses a darkfield microscope to
not only observe the plasma and the blood cells, but to also find out
the causes of the unbalances. A deep analysis of the different structures brings the information of the things the body is trying to fix. It
also provides a tool to observe if the treatments are being effective ornot. After 40 years of working and developing this method, the Holographic analysis offers an invaluable information to understand theconnection between symptoms and causes.

Correspondence to:Adam Bigelsen
E-mail: adambigelsen@gmail.com

123

Title: Let´s talk about herbal medicine:
Insights from an international medical
student project to enhance doctor-patient communication in herbal medicine
Ortiz Miriam1, Schiff Elad2, Teut Michael1,
Brinkhaus Benno1, Ben Arye Eran3
1Institute for Social Medicine, Epidemiology and
Health Economics, Charité - Universitätsmedizin
Berlin, Corporate Member of Freie Universität
Berlin, Humboldt-Universität zu Berlin, and Berlin
Institute of Health, Germany
2Rappaport Faculty of Medicine, Technion, Haifa,
Israel Internal Medicine, and Complementary &Integrative Medicine Service, Bnai Zion Medical
Center, Haifa, Israel
3Integrative Oncology Program, Oncology Service,
Lin Medical Center, Clalit Health Services, Haifa,
Israel Rappaport Faculty of Medicine, Technion,
Haifa, Israel
Let´s talk about herbal medicine: Insights from an international
medical student project to enhance doctor-patient communication in
herbal medicine
Introduction: In the framework of an international cooperation project of the Bnai Zion Medical Center, and the Technion, Israel, and Charité Universitätsmedizin Berlin, Germany, medical students from bothcountries and Complementary and Integrative Medicine (CIM) experienced mentors worked together to improve doctor-patient communication skills by CIM strategies. Five groups evolved from the process:Traditional Chinese Medicine; mind-body medicine; touch therapies;
mindful mindset; and naturopathy/herbal medicine. The goal of thenaturopathy/herbal medicine group was to design an educationale-learning module for medical students and physicians in order to improve doctor-patient-communication regarding herbal medicine. The
project was supported by the German-Israeli Future Forum.
Methods: The naturopathy/herbal medicine group consisted ofthree Israeli and two German students (age 23-30) and two mentors
with education and long-term experience in naturopathy and herbal
medicine. Between April 2017 and March 2018 the project group met
in three intensive working phases once in Haifa and twice in Berlin.
They worked out an e-learning module following a literature researchand self-experience with herbal therapy.
Results and Discussion:
Together with the mentors, the students developed an educational module consisting of a film- documented doctor-patient roleplay(http://www.b-zion.org.il/pages_e/6683.aspx)on taking history about
herbs, and instructions about websites for herbal treatment. The video includes a short quiz and a pocket guide on communication strategies while talking about herbs and supplements with patients.
Conclusion:
The intensive cultural exchange and explorative process in this international medical student collaboration led to substantial improvements in patient-doctor communication strategies as reported byparticipating students. The results of this international collaboration,
specifically the educational modules, can be used by medical students
and physicians to enhance communication with patients regarding
herbal medicine.
Correspondence to: Ortiz Miriam E-mail: miriam.ortiz@charite.de124

BOOK OF ABSTRACTS | 12th European Congress of Integrative Medicine · 1st International Symposium on Integrative Health and Education

Title: The potential of videography
and expert interviews for differentiating between motivation andneed for recreation of neurorehabilitation patients in physiotherapy
and music therapy sessions
Claudia Wenzel1, Iris Zoderer1, Sun Sun Yap1, Patrick Simon1, Mona Duer1, Gerhard Tucek1 11IMC
University of Applied Sciences, Josef Ressel Centre Horizons of personalized music therapy, Department Health Sciences, Piaristengasse 1, 3500
Krems, Austria
Objectives
As part of a larger mixed-methods study focusing on the optimum
time for non-medical therapies (e.g. physiotherapy, occupational
therapy, music therapy) in the field of neurorehabilitation, the main
objective of this part of the study was to differentiate between motivation and need for recreation of patients during physiotherapy ormusic therapy sessions through videography and interviews.
Material and method
Data collection included videographies (n=6) of physiotherapy andmusic therapy sessions as well as qualitative expert interviews (n=6).
The data was collected in an Austrian neurorehabilitation center in arural area. Grounded Theory was used both as a methodology andas a method of data analysis (coding). The computer software Atlas.ti(Vers. 7.0) was used for both interview and video analysis.
Results
Experts can differentiate between motivation and need for recreation of patients by analyzing physiotherapy and music therapy
video data. In any case, there are no specific categories referring only
to motivation or need for recreation of patients. “Posture & motor
function”, “spoken language”, “activity”, “concentration” “facial expression” and “interaction” were the most frequently categories usedby experts.
Conclusions
As there are no unique categories for motivation or need for recreation of patients, the context of the therapy must be taken into accountas well as parameters like the subjective motivation of the patient.
The results can be used for the development of a tool for identifying
motivation or need for recreation of patients undergoing neurorehabilitation, to enhance personalizing and therefore improving the quality of non-medical therapies.

Correspondence to:
Claudia Wenzel
E-mail: wenzel.resselzentrum@fh-krems.ac.at

Title: What´s going on in A1 Integrative Medicine Evidence? A1 en Medicina integrativa y tradicional
Amelia Cantarero García1, Javier Postigo Sánchez1, Alberto Pardos Cañardo1, Tomás Álvaro
Naranjo2, Arturo Luján Acosta Serrano1, Elixabet
Maisterrena Alemán3
1Sescam
2Centro De Medicina Integrativa Arjuna
3Buchinger Wilhelmi
Objetivos:
Poner en conocimiento y utilizar la máxima evidencia científica enla práctica clínica diaria en medicina integrativa y tradicional.
Valorar los tratamientos con mayor seguridad y eficacia en las patologías más comunes. Material y método:
Basado en la graduación SORT (Strengh of Recommendation Taxonomy) (ABC) y en el grado de daño potencial (1,2, 3). A través delos trabajos publicados en Integrative Medicine , con el permiso delautor, David Rakel hacemos un escrutinio de la evidencia A1 de todo
tipo de tratamientos desde el farmacológico, dieta, ejercicio, fitoterapia, suplementos, bioenergética, psicológicos, acupuntura, asistencia
espiritual, homeopatía. Extraemos la graduación A1 de las patologías
más comunes.
Análisis:
Dentro de 15 especialidades médicas concretamos las más frecuentes 71. Siendo A la mayor evidencia y 1 la ausencia o el mínimo daño
potencial.
Resultados:
De las 71 patologías evaluadas en un 23,9 % no se encuentra evidencia tipo A1.
El tratamiento más importante A1 es la dieta con indicación en un
38% de las patologías. Le sigue el ejercicio con 30,9%, los suplementos
29,5% y la psicoterapia con 21,1% de las indicaciones en enfermedades médicas.
Un 14% se beneficia de acupuntura. El tratamiento con fármacos
A1 supone el 12,6% y con fitoterapia el 9,8%.
La restricción o evitación de ciertos alimentos, sustancias y ó fármacos constituyen el tratamiento más seguro y eficaz en el 35% delas patologías.
Discusión:
Apenas encontramos fármacos con evidencia máxima y seguridad
completa (la mayoría A2, con lo que no están exentos de daño potencial).
Conclusiones:
Curiosamente la mayor evidencia científica se acerca a los orígenes de la medicina natural: la dieta y el ejercicio. Con la importanteaportación de la psicoterapia en la patología médica: Relación cuerpo-mente.
Medicina integrativa con evidencia científica y seguridad para curar,
aliviar, acompañar el proceso de vida del ser humano.

Correspondence to:Amelia Cantarero García
E-mail: ameliacantarerogarcia@gmail.com

BOOK OF ABSTRACTS | 12th European Congress of Integrative Medicine · 1st International Symposium on Integrative Health and Education

125

Title: Modulated electro-hyperthermia
induced stress can potentiate doxorubicin efficacy in vitro and induce immune response in vivo in C26 mousecolorectal carcinoma cell line

Title: The Havelhöher Eurythmy Questionnaire (HEQ-2): A peer-report instrument to assess movement, language
and gesture expression during Eurythmy Therapy

Tamas Vancsik1, Gertrud Forika1, Eva Kiss2, Andrea Balogh3, Tibor Krenacs1
11st Department of Pathology and Experimental
Cancer Research, Semmelweis University
2Oncological Centre, Semmelweis University
3Institute of Clinical Experimental Research, Semmelweis University

Annette Mehl1, Hans Broder von Laue2, Marcus
Reif3, Christoph Gutenbrunner4, Arndt Büssing5,
Matthias Kröz6
1Research Institute Havelhöhe, Berlin, Germany2Öschelbronn, Germany
3Society for Clinical Research, Berlin, Germany
4Clinic for Rehabilitative Medicine, Hannover
Medical School, Hannover, Germany
5Institute of Integrative Medicine, University ofWitten/Herdecke, Germany
6Research Institute Havelhöhe, Berlin, Germany;
Institute of Integrative Medicine, University ofWitten/Herdecke, Germany; Department of Internal Medicine Havelhöhe Hospital, Berlin, Germany; Institute for Social Medicine, Epidemiology
and Health Economics

Modulated electro-hyperthermia (mEHT; oncothermia) at ~42°C
can selectively induce damage in malignant tumors. Here we assessed mEHT as a chemosensitizer in vitro; and as an inducer of immune
response in vivo.
C26 mouse colorectal adenocarcinoma cell line was treated withmEHT (42oC) alone or in combination with doxorubicin (mEHT+Dox)
in vitro. In vivo, C26 allografts were treated with mEHT alone or in
combination with a chlorogenic acid rich T-cell promoting extract ofMarsdenia Tenacissima (MTE). Stress response, cell death, apoptosis
and proliferation related markers were detected using qPCR, resazurin viability assay, clonogenic assay for counting tumor stem-cells,
flow-cytometry, immunocyto- and immunohistochemistry.
mEHT induced significant hsp70 and calreticulin protein release(24h) and reduced the number of tumor stem-cell colonies. Significant decrease of anti-apoptotic and elevation of pro-apoptotic mRNAlevels were detected, besides increased P21 expression. Between
24-48h mEHT reduced tumor cell-viability by apoptosis, which was increased after mEHT+Dox combination. Nuclear phospho-p53(Ser15)
protein levels were significantly increased in treated groups, whilephospho- Akt(Ser473) levels were reduced only after mEHT and mEHT+Dox.
Damage associated molecular pattern (DAMP) signals were released from mEHT treated tumors. In vivo, a single shot of mEHT led
to progressive tumor damage and accumulation of CD3+ T-cells andS100+ antigen presenting dendritic cells. These changes could also beseen in the distant tumors when mEHT was combined withMTE.
mEHT treatment induced irreversible cell stress, apoptosis and therelease of DAMP signals in colorectal cancer models. In vitro data revealed p21-mediated growth arrest and apoptosis possibly due by p53
signaling. Furthermore, mEHT promoted the uptake and potentiatedthe cytotoxic effect of doxorubicin. In vivo, mEHT induced progressive tumor damage with increasing immune-cell infiltration indicated asecondary tumor destruction by immunogenic cell death both locallyand systemically at distant tumor sites.
Supported by the NKFIH-NVKP_16-1-2016-0042 grant of the Hungarian Government.

Correspondence to:Tamas Vancsik
E-mail: vancsik.tamas@gmail.com

Introduction: Eurythmy Therapy (ET) is a mindfulness-oriented therapy commonly used in anthroposophic medicine. However, validated
instruments to evaluate patients’ movement, language and gesture
expression are underrepresented.
Method: In a comprehensive cohort study evaluating ET as part ofa multimodal intervention in breast cancer patients with cancer-related fatigue, we validated the Havelhöher Eurythmy Questionnaire(HEQ). Its 83 items were completed by eurythmy therapists capturing
single ET sessions for each patient regarding movement, language andgesture expression. Baseline and 10- week ET sessions of 68 patientswere assessed. Interrater-reliability (IRR) was estimated by Cohen’s
weighted kappa (κw) for all items, followed by a reliability and principal component analysis (PCA). Additionally, patients completed theself-report measures Satisfaction with Eurythmy Therapy (SET) andInner Correspondence with Movement Therapy (ICPH).
Result: In 41 of the 83 items IRR met the statistical threshold (κw= 0.25), with a mean weighted kappa of κ w
̅ = 0.40 (SD = .18, range =0.25 to 0.85). Reliability analysis resulted in exclusion of 25 items withinsufficient item-total correlations < 0.40. A PCA with 16 items revealed 3 subscales and 1 single item: 1. Mindful Movement (7 items), 2.
Activity & Skills (5 items), 3. Gait Pattern (5 items) and Respiration (1items), explaining 66% of total variance. Psychometric properties forthe modified HEQ-2 questionnaire showed sufficiently high reliability
with Cronbach’s alpha coefficients ranging from 0.84 to 0.87 acrosssubscales. Subscale inter-correlations were small to moderate (0.24- 0.67, p < 0.05). Respiration and Mindful Movement correlated with
the ICPH (r =0.22 and 0.24, respectively; all p < 0.05). No correlation with the SET
was found. Conclusion: The HEQ-2 is the first validated peer-report
instrument to measure movement,
language and gesture expression during ET and reveals sufficiently
high consistency and reliability. Further studies to measure responsiveness and applicability are indicated.
Correspondence to: Annette Mehl
E-mail: Annette.Mehl@havelhoehe.de

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BOOK OF ABSTRACTS | 12th European Congress of Integrative Medicine · 1st International Symposium on Integrative Health and Education

Title: Clinical study on the efficacy of Pluralistic Homeopathy in Asthma
Rosalia ZUERAS GELABERT1
1Rosalia Zueras Gelabert
OBJECTIVES
The objective was to analyse the response to homeopathic treatment in patients diagnosed with chronic bronchial asthma and assess
its effectiveness.
MATERIAL AND METHODSThis is a retrospective study of 171 patients treated by the same homeopathic doctor for bronchial asthma for 28 years. They consulted
for frequent acute crises that required urgent or permanent attention
to respiratory distress and superinfections. The patients were selectedaccording to the following criteria: having been diagnosed and treatedin a health centre, permanently continuing classical treatment and having followed homeopathic treatment for a minimum of one year.
Symptom evolution time and treatment performed were collected.
ANALYSIS
The main remedy and the complementary remedy are analysed.
The follow-up time, the onset of remission of the symptoms and theresult of the treatment.
RESULTS
The ages of the patients range from 1 to 71, 50% were under 20
years old.
The most used remedies were Natrum Muriaticum and Ignatia. The
onset of remission of symptoms was observed in a range from thefirst month to 48 months. The total follow-up time was between 2
and 16 years.
In 58% of cases, patients stopped needing any treatment and weredischarged by the reference health centres. There was no improvement in just 16% of cases. An association was observed between thebest results and the youngest age of the patients and the shortest
evolution of the asthmatic process.
DISCUSSION
Part of the efficacy of homeopathy can be considered related to thecontemplation of emotional causes in addition to physiological ones.
CONCLUSIONS
Homeopathy proves to be effective in the treatment of asthma. The
youngest age and the shortest time of evolution of the symptoms arefactors that favour a better response to the treatment.
Correspondence to: Rosalia Zueras Gelabert
E-mail: rzueras@gmail.com

Title: Indications of Calendula according to thelevels of evidenceMontserrat Nolla Benavent1, Carmen Porcar Castells2 1Hospital Joan XXIII, Tarragona
2Hospital San Joan, Reus
Background and Objectives:
Natural and complementary therapies require scientific evidence
for their application in healthcare centres.
The objective of this work has been the search for studies related
to the use of calendula and the subsequent classification according to
the different levels of evidence.
Material and Method:Comprehensive bibliographic search and subsequent critical review.
The consulted databases were: Cuiden, Pubmed, Cinhal and Google Scholar. Writings in English or Spanish and with full text availability
were included. A total of 150 articles were identified.
In addition, manual searches were conducted on websites, institutions, associations and professionals of recognised prestige.
Results and Discussion:
In the Pubmed database there are 5 randomised clinical trials published less than 5 years ago Calendula is indicated for dependency
lesions, diabetic ulcers, radiodermatitis, gingivitis, venous ulcers.
Classification according to the levels of evidence.
Studies show that calendula stimulates both proliferation and migration of fibroblasts, which are involved in the early stages of theprocess of reconstruction and granulation of wounds.
Specification of the selection of articles. Conclusions:
The bibliography shows that calendula therapy is safe, with goodresults. However, more randomised clinical trials with a number of patients on a larger scale are missing, to establish a more priority use in
the application of marigold in wounds and ulcers.
Correspondence to: Montserrat Nolla Benavent
E-mail: montserratnollab@gmail.com

BOOK OF ABSTRACTS | 12th European Congress of Integrative Medicine · 1st International Symposium on Integrative Health and Education

Title: The efficacy of Homeopathy in thetreatment of Acute Otitis in children
Francesco Macrì1, Cosimo Lanza, Luisella Zanino,
Lucia Romeo, Alfredo Di Caro, Tiziana Di Giampietro
1CAM study group of Italian Society of Pediatrics
Aim
The aim of the study was to verify the efficacy of the homeopthy inthe treatment of the acute otitis in children and is effect in reducing
the use of antibiotic therapy.
Materials and methods
6 pediatricians of the Study Group of CAM inside the Italian Societyof Pediatrics contributed to the study. 90 children with otalgia havebeen enrolled with no more than 12 hours fever, divided according
to randomization in 2 groups (A and B) of 45, comparable for age, sex
and relevance of the clinical picture at onset.
The parameters considered were fever and otoscopic feature andevaluated at time 0 and after 48 hours.
The children of the group A were treated with anti-inflammatory
drugs in 48 hours, the children of the group B with homeopathic medicines selected according to phenomenological criteria shared by theoperators in addition to anti-inflammatories. Antibiotic therapy wasprescribed in absence of improvement at the 48-hour check-up
Results
Group A: average age 4a-11m, 24 males. At T0 33 patients (73%)
febrile, average otoscopy score 2.2; at 48 hours, febrile 16 (35%),
average otoscopy score 3.0, antibiotic need 28/45 (62%) Group B:
average age 5a-5m, 27 males. A febrile, average otoscopy score 2.6;
at 48 hours, febrile 13 (28%), average otoscopy 1.7, antibiotic need
15/45(33%)
Discussion
Our data show a more favorable trend in patients treated with homeopathic therapy compared to patients treated with conventional
therapy, both in terms of clinical improvement and, above all, in termsof reduction of the antibiotic prescription.
Conclusions
Homeopathic therapy in the treatment of acute otitis of children
reduces the use of antibiotic therapy, fighting the antibiotic-resistance phenomenom
Correspondence to: Francesco Macrì
E-mail: profmacri@gmail.com

127

Title: Launching a Collaborative International Medical Education Initiative in Integrative Oncology: Lessons
from a MOOC on Herbal Medicine
Erez Baruch1, Miriam Ortiz2, Noah Samuels3,
Eran Ben-Arye1 1Clalit Health Services
2Charité - Universitätsmedizin Berlin Campus
Charitè Mitte
3Technion Faculty of Medicine
Background & Objectives: Medical schools and postgraduate medical education programs provide only limited and cursory programson complementary/integrative medicine (CIM), if at all. We present
a Massive Online Open Course (MOOC) in Integrative Oncology andherbal medicine, addressing implications for international collaboration in undergraduate and graduate medical education.
Material and method: The MOOC on traditional herbal medicine
in supportive cancer care (Technion, Israel; Coursera Online Learning
Platform), is a 15-week program with 60 online lectures of 10 minutes(11.7 hours); 13 individual chapters; 27 interviews with leading professionals in the field of Integrative Oncology; and 2 simulated interactions between Integrative Physicians and oncologypatients.
Results: After 5 months, the MOOC has been visited by 3200 Coursera subscribers, with 773 enrolled, 470 beginning and 69 who havesigned up for certification. The majority (60%) are female, 31% between 25-34 and 25% between 35-44 years old. A third (30%) have a
Bachelor’s degree, 26% a Master’s and 12% an MD degree. Enrollees
are from 85 countries, including the U.S. (29%), Israel (18%), India(5%), the United Kingdom (4%), Canada and Brazil (each 3%), and Germany and China (each2%).
Discussion & Conclusions: Medical education in Integrative Oncology and herbal medicine is feasible by a MOOC at the undergraduate
and postgraduate levels. While a MOOC delivers a theoretical base
there is also a need for experiential interactions. These will be provided in a follow- up international program, in which mentors fromthe field of CIM will provide practical teaching in herbal medicine tostudents and healthcare practitioners in leading faculties of medicine.

Correspondence to:
Erez Baruch
E-mail: erez.baruch@gmail.com

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Title: International cross-sectional study
on the effectiveness of Biofield Therapy
for the relief of various symptoms
Kiyoshi Suzuki1, Seiya Uchida1, Tomoaki Kimura1, Hiroshi Katamura1, Hideaki Tanaka1 1MOA
Health Science Foundation
Objective: To investigate whether the effectiveness of biofield therapy for relieving various symptoms differs across countries/regions
and to determine factors associated with change in outcomes.
Methods: This study involved 12,101 participants in total aged 16
or older from 14 different countries: 7,555 from Japan, 1,494 from
Latin America (Argentina, Brazil, Chile, Mexico, Peru), 1,441 from
Hawaii, 1,281 from Asia (Taiwan, Thai, South Korea), 330 from Europe(Belgium, France, Portugal, Spain). They received a single session of
biofield therapy (Okada Purifying Therapy: OPT) lasting 30 minutes or
longer from the volunteer practitioners. Before and after OPT, theyreported the severity of physical pain, autonomic symptoms (palpitation, dizziness, etc.), psychological symptoms (irritation, depression,etc.) and overall symptoms. The team examined the adjusted odds
ratio of the variables related to the change of each category of symptoms.
Results: Of the total participants, 75.8%, 73.7%, 78.6% and 77.6%
reported an improvement in the severity of physical pain, autonomic, psychological and overall symptoms, respectively. Those rates,
however, varied based on the participants’ country/region and theduration of OPT session. The improvement rates were consistently
highest among participants from Latin America (odds: 3.0-5.0, reference category: participants from Japan) and who had received OPT
for 51 minutes or
longer (odds: 1.4-1.8, reference category: 30 minutes). The reason
for participation, past experience, and the location of receiving OPT
were also associated with improvement of different symptoms.
These findings occurred regardless of the participants’ age or presence/absence of illness. In terms of safety, the exacerbation rates ofsymptoms were 2.5%, 1.7%, 0.8% and 2.8%, respectively. Of those
who expressed exacerbation of symptoms, 72% recovered in a few
hours. None of them needed emergency medical treatment.
Conclusions: The effectiveness of a single session of biofield therapy differed across countries/regions, and a longer duration of therapy
were associated with better outcomes.
Correspondence to: Kiyoshi Suzuki
E-mail: k.suzuki@mhs.or.jp

Title: Electroacupuncture vs. Shamprocedure for the treatment of fatigue in patients with quiescent inflammatory bowel disease
Marcelo Tegiacchi Schvetz1, Dario Gaarcia Rojo1,
Susana García Molina1, Xavier Calvet1, Diana
Horta1, Albert Villoria1
1Hospital Taulí, Sabadell
Background and Aims: Fatigue is a common symptom in inflammatory bowel disease (IBD) and often persists despite clinical remission. Acupuncture has been shown to be effective for treating fatigue in many chronic diseases. The main objective of the study wasto assess the efficacy of electroacupuncture (EAc) vs. sham electroacupuncture (ShEAc) and wait-list (WL) for treating fatigue in patientswith quiescent IBD in a single-blind randomized trial. Methods: Fifty-two patients with IBD in clinical remission and fatigue were randomized to EAc vs ShEAc vs WL. Patients in EAc and ShEAc groups received nine sessions over eight weeks. Fatigue was evaluated with the
IBD-validated Functional Assessment of Chronic Illness Therapy-Fatigue Scale (FACIT- FS). Results: Baseline characteristics were similar in
the three groups. Both EAc and ShEAc presented improved FACIT-FS
scores compared with baseline: the respective improvements were
9.53 (95%CI: 6.75-12.3, p<0.001) and 5.46 points (95%CI: 2.7-9.7, p=
0.015). No significant
changes were observed in the WL group. Comparing treatmentgroups, EAc was non-significantly better than ShEAc (EAc:33.27,
ShEAc:28.13, p=0.168); both EAc and ShEAc improved fatigue scoressignificantly compared to WL (24.5; p=0.01 and 0.04 respectively).
Conclusions: Both EAc and ShEAc reduced fatigue scores in IBD patients when compared to WL. No differences were observed between
EAc and ShEAc, although the study was not powered to rule out a difference.
Acupuncture may offer improvements to patients with few othertreatment alternatives.
Correspondence to: Marcelo Tegiacchi Schvetz
E-mail: 24655mts@gmail.com

BOOK OF ABSTRACTS | 12th European Congress of Integrative Medicine · 1st International Symposium on Integrative Health and Education

Title: “Words that treat”. An Internet-based teaching of “Crisis dialogue”, a verbal tool for the care ofacute psychosis. Pilot intervention
Bertrand Graz1, Arnaud Vergères2, Anne Leroy3,
Jean-Christophe Leroy3, Alexia Stantzos4, Gilles
Bangerter5
1Antenna Foundation, Geneva
2University of Geneva
3L’Îlot - Les Journées de la Schizoophrénie 4Centrede psychiatrie du Nord Vaudois 5Haute École desanté Vaud
Objective
The “Crisis Dialogue” (CD) can be used by non-specialists including
family members of psychotic patients (with e.g. mania or schizophrenia). A precise and specific verbal tool, CD requires 3-5 minutes of talk.
It is designed to help calm down, reassure and ideally it facilitates thedeconstruction of the delirium and delusions. It is still not conventional medicine, although it has been subjected to a randomized controlled trial and to field tests in several countries. This technique is meant
to complement usual work in emergency psychiatry.
An Internet version of the CD teaching material was made available
to the whole French-speaking world on the website of the “Journées
de la schizophrénie”. The objective was to help spread a techniquethat has already proven helpful and then to assess whether the teaching material was sufficient for a fair understanding of the technique.
Material and Method
An internet questionnaire was filled by participants who wanted
to test their understanding of the CD after use of the internet-basedteaching material.
Results
During the first 2 months of internet availability, the CD teaching
page was accessed by 1028 persons. Among them, 131 downloaded
the attached teaching material, 139 looked at the provided on-line
questionnaire and 98 tested their knowledge with it. In 11 of the 13
questions a correct answer was found by 80-95% of the respondents.
Two concepts seemed to remain more difficult to grasp: how CD could
help the patient “see his/her delirious thoughts in another manner”(77% missed this point); the way CD can help “de-construct the delirium” (53% missed this point) Conclusion
In this pilot study, the internet-based teaching of Crisis Dialogue
appears to be a promising tool to make the “words that treat” available to those concerned by psychosis. A feed-back questionnaire
helped to spot parts of the teaching material that still need to be improved.
Correspondence to: Bertrand Graz
E-mail: bertrand.graz@unige.ch

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Title: A three year observational
study of a standardized Ayurvedic
medicine (RA-1) in the treatmentof Rheumatoid Arthritis (RA) and if
required in combination with modern medicine disease modifying anti-rheumatic drugs (DMARD): An integrative medicine approach
Manjit Saluja1, Toktam Kianifard2, Arvind
Chopra1 1Center for Rheumatic Diseases
2Rheumatology Research Centre, Tehran University of Medical Sciences, Islamic Republic of IranObjective: To evaluate the long term effectiveness of RA-1 both asa monotherapy and in combination with DMARD for inadequate response
Material and Methods: 165 consenting symptomatic active disease
patients were enrolled into the current a-priori prospective observational design study. Patients were naïve for DMARD and had just completed a 16 week placebo controlled evaluation of RA-1 (published);
57 were on low dose steroids. RA-1, a multi-plant formulation, wasstandardized using modern pharmaceutic methods. 57 patients wereon fixed low dose prednisone. Patients were examined every 10-14
weeks in a routine community rheumatology practice using standard
norms. Patients continued RA-1 (2 tablets twice daily) throughout the
study period along with healthy life style but no other Ayurvedic advise. Based on clinical judgement, rheumatologist added DMARD and/or steroid to patients with inadequate response; chloroquine and/or
methotrexate were usedpredominantly.
Analysis: Treatment response was assessed using American Collegeof Rheumatology (ACR) efficacy measures and the benchmark ACR
20% improvement index. Standard statistical software (SAS and SPSS)
were used; significant p <0.05.
Results: 158, 130 and 122 patients completed evaluations at 1, 2
and 3 year primary end point. ACR 20 response (range 34-40%) remained stable (p=0.33). All round sustained improvement included
function and quality of life. Steroids and DMARDs were prescribed in
42-49% and 20-34% patients respectively for varying periods. 40%
patients were controlled with RA-1 monotherapy. 77% patients reported mild, adverse events; nonewithdrawals.
Discussion: Treatment of RA is fraught with drug toxicity, poor access and affordability. Can modern medicine and Ayurvedic drug be
combined for a better therapeutic response? We describe a novel integrative medicine strategy (RA).
Conclusion: RA-1 is a safe and effective drug for long term management of RA in several patients. If required it can be strategically combined with DMARDs and steroids.
Correspondence to: Manjit Saluja
E-mail: msaluja345@gmail.com

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BOOK OF ABSTRACTS | 12th European Congress of Integrative Medicine · 1st International Symposium on Integrative Health and Education

Title: Reversal of grades in Avascular
Necrosis of Hip Joint through Ayurveda
Panchakarma Treatment: Case Series ofSeven Patients
Dr. Pardeep Sharma1 1Sukhayu Ayurved
Background:Avascular Necrosis of the hip joint (AVNOH) is a disabling conditionof the hip joint commonly affecting young individuals. Use of alcoholand corticosteroids are two common
pathological causes. These causative factors block blood arteries carrying blood to head of femur. And lack of nutrition leads to necrosis.
AVNOH is a progressive condition. Where grades keeps on increasing with decay of the bone and cartilage of the head of femur. The ultimate destination for these patients is- total hip replacement (THR).
In this backdrop, this clinical work was aimed on the pathological reversal of the AVNOH. These are 7 cases done at an Ayurveda hospitalin India between 2017 to 2019, where we got reversal in grades of the
AVNOH through Ayurveda treatment.
Material and Method:
These are seven case studies. 6 male and 1 female. 2 of these patients were in grade I and 1 in grade IV and 4 in grade III.
Panchakarma Treatments were given to all the 7 patients. Whichincluded Tikta Siddha Ksheer Basti in Niruha and Anuvasana pattern.
First session of Basti was 15 days (Karma Basti) followed by 8 days
(Kaal Basti). MRIs were got done after 6 months after initiation oftreatment.
Results:
All of these cases not only showed great relief in signs and symptoms like- pain, limping while walking but also in these cases reversalof the Avascular necrosis was evident.
Grade I patients were reported without AVNOH and two grade III
patients shifted to grade II and Grade IV patient reversed to III.
Discussion:
If we follow the classical text of Ayurveda and work on reversal ofpathology according to principles of Ayurveda, reversal of the progressive disease like AVNOH is possible. Which might be very successful if
done in integration with modern medical science.

Correspondence to:
Dr. Pardeep Sharma
E-mail: aatray06@gmail.com

Title: Retrospective study of a standardized acupuncture/acupressure protocol
for hot flushes in women with breast
cancerNoemi Zurron1, Chantal Berna11Integrative and Complementary Medicine Center (CEMIC), Pain Center, Division of Anaesthesiology, Lausanne University Hospital, Universityof Lausanne, Rue du Bugnon 46, 1011 Lausanne,
Switzerland
More than 60% of breast cancer survivors develop hot flushes (1).
Acupuncture is an option (Grade C evidence) for the management of
hot flushes (2). An A standardized acupuncture protocol in a specificstudy of menopausal symptoms showed comparable results to an individualized approach (3). Acupressure can be an effective self-care intervention to manage cancer side effects (4). To our knowledge, there
is no study investigating a combined and standardized acupuncture/
acupressure (AcuP2) protocol for hot flushes in breast cancer survivors.
We conducted a retrospective chart review in order to compile thereported effects following a protocolled AcuP2 treatment. This data
will facilitate the planning of a prospective controlled study. Study
population and selection criteria: Women with breast cancer complaining of invalidating hot flushes (N=25) addressed by their oncologist (during 2018) for acupuncture at a University Hospital Integrative
Medicine Center.
Intervention: Minimum 8 sessions of acupuncture with a standardized WMA style protocol of 8 points. Whenever possible, patients received instructions to practice daily acupressure on all points. Outcomes collected: number of sessions, patient’s self-reported diminutionof frequency (Y/N) and intensity (Y/N) of flushes.
Eleven patients were excluded (5 never initiated treatment, 6 withongoing treatment). The data of N=14 was analyzed: 13 reported apositive outcome (yes on both criteria) and 1 a partial response. Ninepatients got AcuP2, and five only acupuncture (including the woman
with a partial response).The mean number of sessions was 8.4 (4-14),
with 5 patients not completing the recommended minimum.
Combining acupuncture and self-delivered acupressure appears tobe efficient in alleviating hot flushes. It might alsoenhance self-careand empower women in their battle against cancer compared to apassive acupuncture protocol. A prospective randomized study will beplanned, using standardized outcomes.
Correspondence to: Noemi Zurron
E-mail: noemie.zurron@chuv.ch

BOOK OF ABSTRACTS | 12th European Congress of Integrative Medicine · 1st International Symposium on Integrative Health and Education

Title: Acupuncture and Moxibustion in
the treatment of breech presentation
at the Hospital Sant Joan de Déu
Cristina Domingo Gómez1, Maite Miranda Garcia1 1Campus Docent Sant Joan de Déu
The WHO recommends that the number of births by caesarean section should decrease to 10-15% of births.
The use of complementary therapies such as acupuncture andmoxibustion, in pregnant women with non-cephalic presentation, hasbeen experienced and the results published, in systematic reviews
and meta-analyses, which promote its use.
Objective
To evaluate the effectiveness of acupuncture and moxibustion
treatment together with the External Cephalic Version (ECV), in pregnant women with non-cephalic presentation, in the third trimester,
to favour the foetus version, compared to pregnant women who only
perform ECV.
Material and Methods
Female Medicine area of the Sant Joan de Déu Hospital in Barcelona. The study is carried out in two phases:
Preliminary experimental phase, with a single group and a second
phase, with a randomised clinical trial.
Results
In the preliminary phase, the version of the foetus at a cephalicpresentation was 53.5%, compared to the expected 30%. In pregnant
women with post-treatment cephalic presentation, vaginal delivery is75%, while those who do not version, have caesarean section97.9%.
In the second phase, in the intervention group, the version is 60.8%
and in the control group 45%, with an improvement of 15.8%.
Caesarean delivery is lower in the intervention group by 12.35%.
Conclusions
The acupuncture and moxibustion treatment is effective in pregnant women with a breech presentation, if it is introduced before thecompletion of the ECV.
Correspondence to:
Cristina Domingo Gómez
E-mail: crispersonal.domingogomez@gmail.com

131

Title: Clowns in Hospitals: Promoting Resilience,
Well-Being, and the Systematic Transformation of
Healthcare
Monica Culen1
1RED NOSES International
Objectives:
For the past 25 years, RED NOSES International (RNI) has provided
psychosocial support to children in hospitals through the use of clown
visits. Clown visits aim to increase children’s emotional well-being andresilience through humour, playfulness, and creativity.
Material and Method:
RNI provides clown visits to 735 medical and social institutions in 11
countries. Clowns practice a sensitive, empathetic style of interactionthat counteracts the depersonalizing aspects of modern medical care,while their adoption of a low-status role allows children to take on a
position of authority and regain control over their situation. Clowns
also have positive impacts on children’s families, letting them releasestress and providing a safe space for them to process both positive
and negative emotions.
Analysis:
The impact of clown visits is measured through regular monitoring
exercises, as well as internal and external evaluations that include thevoices of medical staff, parents, and children through surveys, interviews, and focus group discussions.
Results:
A substantial body of research shows that clowns reduce the anxiety of hospitalized children and their families. In the long term, clowns
create a lasting change to the hospital environment. For example, arecent survey of medical staff in Palestine visited by RED NOSES showsthat clown visits make them aware of specific strategies to show empathy to children. This kind of feedback from medical staff suggeststhat clown visits help to transform hospitals into spaces that no longer
undermine but rather support children’s confidence, interpersonal
engagement, and emotional well- being.
Discussion:
Clown visits provide an immediate source of relief and psychosocial
support, while in the long term they promote systematic improvements to the provision of holistic, humanistic healthcare.
Conclusions:Clowns are increasingly understood by families, medical staff, andministries of health as an indispensable addition to the hospital environment.

Correspondence to:
Monica Culen
E-mail: maggie.roessler@rednoses.eu

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BOOK OF ABSTRACTS | 12th European Congress of Integrative Medicine · 1st International Symposium on Integrative Health and Education

Title: Effect of yoga on pain, functional
disability and corticomotor excitability
in chronic low back pain patients
Dr suvercha arya dr renu bhatia1, Ms srishti nanda1, Dr raj kumar yadav1, Dr venkatraman srikumar1
1All india institute of medical sciences, new delhi,
india
Objectives: The aim was to study objectively, effect of yoga on pain,
functional disability and corticomotor excitability in Chronic Low Back
Pain (CLBP) patients.
Material and methods: It was a randomized controlled study conducted at a tertiary hospital in New Delhi, India. Thirty (females, n =18) CLBP patients, consented and were randomly assigned to yogagroup or standard care group. Patients with other systemic illness,
neuropathy and othercontra-indications to transcranial magnetic stimulation were excluded. Patients reported severe pain, had severe disability and reduced
corticomotor excitability at baseline.
Pain-related outcomes were assessed by Visual Analogue Scale(VAS) and Oswestry Disability Index (ODI). Functional assessment of
low back disability and corticomotor excitability were objectively assessed with the American College of Sports Medicine’s Sit and Reach
Test and recording Resting Motor Threshold (RMT), Motor Evoked Potential (MEP) respectively.
The intervention consisted of a 4-week supervised yoga program
including Asanas (twenty-one selected), Pranayama (breathing practices) and Meditation. Standard care group practiced at home exercises
instructed by the physiotherapist.
Analysis: Data was analyzed using GraphPad Prism version 8.0.
D’Agostino-Pearson and Mann- Whitney U tests were applied for determining normality and for comparison of the groups respectively.
Results: The data had a non-Gaussian distribution. There was a significant reduction in VAS and ODI scores after yoga intervention (p =0.001 and p= 0.001 respectively). Yoga group, when compared to standard care group, had significantly higher reduction in pain (p=0.045)
and disability scores (p=0.035). Spinal flexibility improved significantly
more in yoga group than standard care group (p=0.001). RMT decreased both in yoga (p=0.033) and standard care group (p=0.048) but
MEP remained unaltered.
Conclusions: In patients with Chronic Low Back Pain, a four-weekyoga intervention reduced pain and pain-related functional disability
and improved corticomotor excitability better than standard care.

Correspondence to:
Dr Suvercha Arya Dr Renu Bhatia E-mail: suvipriarya@gmail.com

Title: A Randomized Controlled Trial ofmHealth Mindfulness Intervention forCancer Patients and Informal Cancer
Caregivers -A feasibility study within an
integrated healthcare delivery system
Ai Kubo1, Elaine Kurtovich1, Sara Aghaee1,
Charles Quesenberry1, Andy Avins1, Andrea Altschuler1
1Kaiser Permanente Division of Research
Objectives: To conduct a pilot randomized clinical trial (RCT) of amobile/online-based (mHealth) mindfulness intervention for cancer
patients and their informal caregivers to assess feasibility and to obtain preliminary efficacy of the intervention in improving quality of life
(QoL).
Material and method: Within Kaiser Permanente Northern California, an integrated healthcare delivery system, we recruited cancer
patients who were receiving chemotherapy and their informal caregivers who had no current meditation practice. The intervention groupused a commercially- available mindfulness program for 8 weeks, 1020 minutes a day. The waitlist control group received usual care.
Analysis: To obtain preliminary efficacy results, we performed repeated measures ANOVA tests comparing change in outcome measures between baseline and 8-week follow-up surveys on distress,
QoL, sleep, mindfulness, and post-traumatic growth. Feasibility wasassessed using retention and adherence rates.
Results: 97 patients and 31 caregivers were randomized, and 74%of the patients and 84% of the caregivers completed the study. Adherence rate to the intervention was high: 65% of the participant practiced at least 50% of the days during the 8-week intervention period.
We observed preliminary efficacy of the intervention on overall andemotional well-being domains of QoL score among patients in theintervention arm compared to those in the control group. Caregivers
in the intervention group experienced increased mindfulness andpost-traumatic growth compared to the controls.
Discussion: We demonstrated the feasibility of conducting an RCT
using technology-delivered mindfulness intervention for cancer patients and their caregivers. Overall, participants appreciated the convenience of being able to access the intervention from any locationand the usefulness of the mindfulness skills they obtained from theprogram in managing stress.
Conclusions: Results from fully-powered efficacy trials would inform the potential for clinicians to use this low-cost, scalable, andwell-accepted intervention to help improve QoL of those affected bycancer and their caregivers.
Correspondence to: Ai Kubo
E-mail: ai.kubo@kp.org

BOOK OF ABSTRACTS | 12th European Congress of Integrative Medicine · 1st International Symposium on Integrative Health and Education

Title: Occlusal disorders rehabilitation
through non-occlusal therapy
Martino Camillo Gianazza1, Roberto Cesare Fagioli1, Marcella Taricco1
1Istituto di Medicina Olistica ed Ecologia Comportamentale “San Lorenzo in Lodi”
Objectives: identify clearly and precisely the purpose of thestudy
Occlusal disorders are even involving remote body districts or postural sindromes. They are usually treated within allopathic and conventional dentistry by modifying the mastication through occlusal
splint, orthodontic appliances or prosthetic dentistry.
Taking in account that the uncorrect mastication usually is a compensation of problems of remote origin from the mouth, the teeth
and the TMJ, the authors proposal is concerning a new and holistic
approach paradigm.
Their objective is the tolerance window widening of occlusal disorders in order to avoid invasive procedures for the mouth. That goalpasses through the rebalance of the main causes of energy deficit
allowing the real etiopathological resolution of the problem.
Material and method:
Study population
Inclusion selectioncriteria
Patients with occlusal disorders as situation molarless, open bite,
deep bite, mandibular retrusion, mandibular deviation, headache,painful pelvis rotation
Exclusion selectioncriteria
Patients wearing occlusal splint or orthodontic appliances
Sample size Twenty
Variables
Esposito’s RPTO - Occlusal Tolerance Range Proprioceptive reset
Measurement methods Applied Kinesiologysemiotics
Analysis
Are considered and valued through the Applied Kinesiology semiotics the following entity: Mudra PBS et al., Occlusal Challenge, T.L.
Therapy Localization of mastication muscles as Anterior Temporal,
Medium Temporal, Posterior Temporal, Masseter, Internal Pterygoid,
External Pterygoid, Upper Trapezius, Sternocleidomastoid
Results
It is possible reset the occlusal negative afference without occlusal
therapy
Discussion
When the holistic dentist is diagnosing an occlusal disorder him
goal is not considering it only according to the measures as angles or
millimeters but valuating it regarding the individual tolerance window
Conclusions:
After identifying and after solving the upstream causes inducing
the mouth to compensate, the occlusal disorders become tolerated
by the patient
Correspondence to: Martino Camillo Gianazza
E-mail: macgianazza@gmail.com

133

Title: A randomized controlled clinical trial investigating the efficiency ofPhysiotherapy on low back pain
Gamze senbursa1, Nihan ozunlupekyavas2, Gulbaltaci3 1Anima rapha private clinic
2Baskent university
3Private guven hospitalObjective: The purpose of this study was to compare the effectiveness of four physical therapy treatment including kinesio taping,exercise, manual therapy and reflexology for lumbar disc pathologies
without neurologic deficit. Materials And Methods: Ninety volunteers with low back pain were randomly divided into four groups asfollows: Group 1, Soft tissue mobilization techniques and stabilization
exercises (n=24); Group 2, Kinesio® Taping and stabilization exercises(n=24); Group 3, Stabilization exercises (n=22); and Group 4, Reflex
Therapy and stabilization exercises (n=20). Visual analog scale (VAS)
scores for pain intensity, goniometric measurements for the range of
motion and hamstring flexibility, the sit and reach test for flexibility,
an isokinetic evaluation for strength at 60°/sec, and a side-plank position test for trunk stabilization were measured. The functional status
was evaluated with the Oswestry Disability Index. All groups were assessed at the beginning, after a four-week treatment and four weeks of follow-up. Analysis: The Shapiro-Wilk test was used to analyze
the normal distribution of sociodemographic parameters within thegroups. Results: The manual therapy and exercise group showedsignificantly greater improvements than the other groups at week 4
and 8 in terms of pain intensity at night and at rest (p<0.05). There
were no significant differences in other tests among groups (p>0.05).
The Kinesio® Taping and Reflex therapy groups showed a decrease inpain during activity and relaxation right after the treatment. Oswestry
Disability Index results showed improvements at the second and thirdassessments, which indicated that patients’ functionality quickly improved after treatment, allowing the patients to be more painless andfunctional when performing activities of dailyliving.
Discussion: Regular stabilization exercise programs seem to be sufficiently effective for decreasing pain and increasing strength and thefunctional level of patients with lumbar disc pathologies.

Correspondence to:Gamze Senbursa
E-mail: gamzesenbursa@yahoo.com

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BOOK OF ABSTRACTS | 12th European Congress of Integrative Medicine · 1st International Symposium on Integrative Health and Education

Title: Effects of Reflexotherapy on postural control measured with Stabilometric
Platform

Title: Stress reduction and team enforcement by Mindfulness: Mindfulness
based intervention (StreAM)

Eudald Tomás-Esmel1, Irene Pérez-cáceres1,
Yolanda Aparicio Rollán1, Neus Esmel-Esmel1 Esmel Terapias1

Mueller-Kaeser Iris1, Schlaeppi Marc1, Fringer
André2, Meichlinger Jasmine3, Mayer Benjamin4,
Kramer Klaus4
1Center of Integrative Medicine, Kantonsspital St.
Gallen ürcher Hochschule für Ang wandte Wissenschaften 3Fachhochschule St. Gallen
4Universität Ulm

Introduction
The posture is the result of the position and orientation of the bodyand the limbs in balance with the movement and the force of gravity,
its main sensory captors, are the feet, eyes, passage and mouth. Reflexotherapy is a modality that applies specific pressures in the reflex
areas of the feet, favouring the regulation of vital energy, promoting
vitality, comfort and well-being.
This study investigated the effects of reflexotherapy on the postural control system. Methodology: Prospective experimental study.
35 nursing students participated in the study. Reflexotherapy wasapplied for 45 minutes, once per week, for 5 weeks. Participants signed an informed consent. They were evaluated by postural analysis
on a stabilometry platform in two conditions (pre-post).
Inclusion criteria: participants had to be enrolled in complementary
techniques. Exclusion criteria: participants suffering from plantar skinlesions, suffering or having suffered balance disorders or being treated with drugs with action in the central nervous system.
Variables: Surface with open eyes (SOE), closed eyes (SCE). Trusted
ellipse area. Length with LOE/LCE. Length depending on the LDSOE/LDSCE surface. Romberg coefficient for the surface (S), velocity (V),length (L) and variation depending on the position measured in Y
(VDY).
Statistical analysis: ANOVA of Repeated Measures with Post-hoc adjustment for Bonferroni was applied. P <0.05 was used as a significance criterion. The results were performed using the statistical package
SPSS V.19.
Results: Significant changes were obtained in the measurements of
SOE, LOE, LDSOE, and in VDY OE /CE. In all the changes the values
approached the average.
Conclusion: The results showed that reflexotherapy had effects on
the muscle tone of the posterior chain and visual control. More studies are necessary to generalise results.
Correspondence to:
Eudald Tomás-Esmel
E-mail: eudald_tomas@hotmail.com

Objective: To evaluate the practicability, effectiveness and sustainability of a concentrated stress reduction training program (modified
according to MBSR, J. Kabat-Zinn) we focused on stress reduction,
quality of life, and team communication within the scope of interdisciplinary and inter- professional co-working teams (physicians andnurses of oncology, surgery, obstetrics) at the Kantonsspital St.Gallen(Switzerland).
Methods: A four week concise program training medical staff(twenty female participants) of three clinical departments (oncology,
surgery, obstetrics) for mindfulness stress reduction: 4 x 2,5h weekly
plus one whole-day retreat (7h) after the third week, while participants should practice formal mindfulness 20-30 minutes daily during
this time period.
Application of a web-based questionnaire (Qa) regarding feasibility
before and after each lesson (six times) and Qb (based on validated,established instruments: MAAS; WHOQoL-BREF; BOSS; KomminO,
TKI), focusing on mindfulness, work-life balance, quality of life, communication and team-clime applied before, immediate and threemonth after the course. Additionally a focus-group interview (FGI)
wasperformed.
Results: The concentrated modified mindfulness intervention seemed feasible. In the context of private life mindfulness appeared mosteffective while in professional day-life integration of mindfulness wasmore challenging. FGI revealed high relevance of mindfulness for all
professions and disciplines. Although not significant, overall intensityof mindfulness increased, while in certain items significant increase
was documented: The impression to fulfill duties and commitments
without being aware of what am I doing as well as physical complaints
decreased during the mindfulness intervention (MAAS: p=0.049;
BOSS: p=0.012-0.034). Quality of life index increased during the mindfulness course most in midwifes (WHO-QoL-BREF: p=0.021) and lesssignificant in staff of surgery and oncology. A slight benefit in communication was documented (KomminO/TKI:p=0.01-0.062)
Conclusion: This evaluated concentrated mindfulness intervention
is feasible and may increase mindfulness in daily routine while qualityof life, team communication as well as team atmosphere may improve.

Correspondenceto:
Mueller-KaeserIris
E-mail: iris.mueller-kaeser@kssg.ch

BOOK OF ABSTRACTS | 12th European Congress of Integrative Medicine · 1st International Symposium on Integrative Health and Education

Title: Is Posturescreen® mobile app
an accurate tool for male and females to evaluate the correlation
between age, body mass index, soft
tissue problems and posture?
Gul Baltaci1, Nazli Sari1, Ayse Uzun1 1Private Guven HospitalObjective: Measurement of posture is important for those with aclinical diagnosis as well as researchers aiming to understand the impact of faulty postures on the development of musculoskeletal disorders. A reliable, cost-effective and low tech posture measure may bebeneficial for research and clinical applications. To determine whether
PostureScreen® Mobile app is a useful, simple tool that is accessible
for healthy people to evaluate the correlation between age, bodymass index, soft tissue problems and posture. Materials and Methods:
Two hundred and sixty- six subjects (n= F:150, M:116, BMI n= Normal:
150, Obese: 116) evaluate postural exam with PostureScreen® Mobile
app, a photographic method. Pictures of subjects were taken in threestanding positions. The app calculated posture variables, including
sagittal and coronal plane translations and angulations. The subjects
were divided into groups depending on their age, gender, body massindex and soft tissue problems features. Analysis: The postural parameters were then compared between female vs male, under 40yrs
vs over 40yrs, BMI normal vs obese and healthy vs posture pathologies. Results: Statistically significant differences (p < 0.05) for somepostural parameters (shoulder p<0.01) were obtained for the healthygroup and posture pathological group during standing position. There
were no significant differences between female vs male, under 40yrs
vs over 40yrs, BMI normal vs obese and posture parameters (p>0.05)
Discussion: Shoulder and posture pathological problems can be interrelated. PostureScreen® Mobile app might represent a useful tool in
the early diagnosis of posture pathologies. This application may have
utility in clinical and research settings.

Correspondence to:Gul Baltaci
E-mail: ygul.baltaci@gmail.com

135

Title: From EBM to Real Life Medicine,
the way to manage chronicity
Gino Santini1
1SIOMI, Italian Society of Homeopathy and Integrated Medicine
Randomized and controlled clinical trials (RCTs) represent the golden standard of the methodology studied to obtain information on
the effectiveness of treatments; for this purpose they are designed totest a therapeutic hypothesis in optimal conditions and in the absence of confounding factors, which gives them a high internal validity,
especially for the management of acute events. In the chronic patient
things change, because the strict and controlled conditions in which
the RCTs are conducted are not always generalizable, mainly because they are performed in very different conditions from normal dailycare. For this reason, we are starting to talk about Real Life Medicine(RLM), taking in consioderation studies on real life where other parameters (PRO, Patient-Reported Outcomes) related above all to thequality of life of the patient should be considered to evaluate subjective treatment: unlike randomized trials, real-life tests have a high levelof generalization, but low internal validity, because the objective shifts
from illness to the patient and from the acute to the state ofchronicity.
The in-depth examination of the patient and his modalities ofadaptation to the external environment constitute the methodological heart of the complementary disciplines, homeopathy in the firstplace, in support of the validity of a methodology, Integrated Medicine, which combines the advantages of EBM (Evidence Based Medicine) with the deepening of the RLM, each with its own prerogatives
and peculiarities; with the advent of the National Plan of Chronicity it
seems that even in Italy public health is becoming aware of how thetwo approaches can be complementary and can guide the interpretation of the mutual results to the benefit of the patient’s health and amore effective treatment of chronicdiseases.

Correspondence to:Gino Santini
E-mail: g.santini@ismo.it

136

BOOK OF ABSTRACTS | 12th European Congress of Integrative Medicine · 1st International Symposium on Integrative Health and Education

Title: Effectiveness of Osteopathy in
Professional Violinists and Violists
with Chronic Neck Pain: Results of a
Randomized Controlled Trial
Gabriele Rotter1, Sylvia Binting1, Theresa Keller1,
Stefan N. Willich1, Alexander Schmidt2, Benno
Brinkhaus1
1Institute for Social Medicine, Epidemiology and
Health Economics, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin,
Humboldt-Universität zu Berlin, and Berlin Instituteof Health, Germany
2Kurt-Singer-Institute for Music Physiology and Musicians Health, Hanns Eisler School of Music Berlin,
Germany; 3 Berlin Center for Musicians’ Medicine,
Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universi
Background
Chronic neck pain (cNP) is one of the most common problems in professional violinists and violists and is often treated with osteopathic medicine (OM). However, the effectiveness of OM in cNP is unclear. Study
aim was to evaluate the effectiveness and safety of OM in professional
violinists and violists with cNP.
Materials and Methods
In a two-armed randomized controlled single-center open trial, adultprofessional violinists and viol-ists with cNP (≥12 weeks) were randomized to either five individualized OM sessions within 10 weeks (OMgroup) or to no intervention (control group, CG). All patients received
paracetamol on demand and a semi-standardized musicians’ medicine
consultation before randomization. The pri-mary outcome parameter
was the neck pain intensity on a visual analogue scale (VAS, 0100mm, 0=no pain, 100=worst imaginable pain) after 12 weeks. Secondary outcomes included neck function (Neck Disability Index Score,
0-100%), perceived stress (VAS, 0-100mm), and safety after 12 weeks,
last follow up after 52 weeks.
Analysis
Statistical analysis included analysis of covariance adjusted for respective baseline value. Results
In total, 62 outpatients were included (OM group (n=28), CG (n=34),
81% female, mean age 41.6±11.1 years, mean baseline VAS neck pain
55.9±11.6mm). After 12 weeks OM was associated with improvementin OM group compared with CG in VAS neck pain (14.6mm [95% confidence in-terval 8.0;21.2] vs. 40.8mm [34.7;46.9], p<.0001), neck function (8.8 [6.7;10.8] vs. 17.2 [15.3;19.1], p<.0001) and perceived stress(30.4mm [21.6;39.2] vs. 46.1mm [38.0;54.2], p=0.0130).
Improve-ment of neck pain and neck function seemed to be maintained until 52 weeks follow up in OM group. No serious adverse eventswere observed.
Conclusions
Five OM sessions were effective compared with no treatment in addition to paracetamol on demand without generating adverse events.
Further high quality RCT research is needed to investigate OM in comparison to standard care interventions in cNP.
Correspondence to:Gabriele Rotter
E-mail: gabriele.rotter@charite.de

Title: Case study projects by a Korean national research agency: Past 12 years andfutureSungha Kim Dr1, Jongbae Jay Park prof2, Sunmi
Choi Dr. 1, Jun-Hwan Lee Dr. 1 1Korea Institute ofOriental Medicine
2Duke university
Objectives
Scientific rigor is a known challenge to establish in heavily individualized practices of traditional medicine. A national research agency in
Korea carried out a 12-year project to promote case reports among
clinics of Korean Medicine (KM). This report aims at providing challenges, achievements, and thoughts for future endeavors.
Methods
We reviewed all the projects executed by the Korea Institute ofOriental Medicine between 2005 and 2017 promoting case reports inclinics of KM. The findings were categorized stage of project development, themes of project stage, achievement, and challenges.
Analysis and Results
The implemented studies include eleven prospective- and five retrospective - case series, and one comparative trial. The project stages
are divided into four, initial (surveying and building a database on Korean acupuncture), transitional (educating Korean Medicine doctors
on writing case reports and building a case report system), stagnation(partially attributable to IRB’s considering case report projects as clinical trial) and resurrection (building a rigorous evidence base from local
clinics). The major challenges included practitioners’ in clinics feelingburdened by the rigor of documentation requirement, the limited
options of usable objective measurement tools available at general
KM, and IRB’s categorizing case report projects as clinical trials hence
imposing unrealistic compliance burden.
Discussion and Conclusions
Promoting case reports in local clinics, while being warranted to remain as a crucial research method to build evidence based KM practice, requires supports from stakeholders including motivated cliniciansof KM, extended use of diagnostic device available at KM practice, andinsightful and flexible regulatory bodies’ decision making.

Correspondence to:Sungha Kim Dr
E-mail: bozzol@kiom.re.kr

BOOK OF ABSTRACTS | 12th European Congress of Integrative Medicine · 1st International Symposium on Integrative Health and Education

Title: Role of hetero-polysaccharides derived fromrare medicinal mushrooms
in Chemoprevention andCarcinogenesis
Vladimir Laudanovic1
1NutriGenomics
Objectives:
1. Understanding role of mechanism of action of mushroom polysaccharides or polysaccharide- protein complexes derived from rare
medicinal mushrooms in activation and modulation of the body’s immune system and in cancer chemoprevention.
It was only in the last 20 years that technology was capable of biochemically dissect traditional medicinal mushrooms and isolate theirmost active anticancer constituents. Many polysaccharide- boundproteins produced by medicinal mushrooms have been classified asanti-tumor chemicals by the US National Cancer Institute. Medicinal
mushrooms are adaptogens, acting as immunomodulators by up-regulating or down-regulating immune system depending if a patient isin an immune-deficient state such as cancer, hepatitis or HIV, in thatcase the number and activity of the white blood cells will increase, in
hyper-immune state such as found in Lymphoma, Lupus or Rheumatoid arthritis, the number and activity of the white blood cells would
drop, while the red blood cells often increase in number. The mechanism lies in controlling differentiation phase of blood cell productionthat signals the body where to direct these immature cells for maturation.
Most important points of anti-tumor and immunomodulating
effects of mushroom polysaccharides are:prevention ofcarcinogenesis.
direct antitumoractivity.
immunopotentiation activity against tumors in combination withchemotherapy;
preventive effect on tumormetastasis.
Hetero-glucans from mushrooms produce their anti-tumor effects
in two ways, by activating many kinds of immune cells of innate andacquired immunity that are important for the maintenance of homeostasis, (such as macrophages, monocytes, neutrophils, naturalkiller cells, dendritic cells) and chemical messengers (cytokines suchas interleukins, interferon, colony stimulating factors), triggering complement and by direct cytotoxic effect by triggering apoptosis in mitochondria of cancer cells.
Cancer chemoprevention is the best intervention before invasive
disease develops and is Non Toxic.

Correspondence to:
Vladimir Laudanovic
E-mail: hypoglosus@gmail.com

137

Title: Patients’ experiences attributed to the use of Angelica
archangelica. Results of a qualitative study and clinical implications for the field of complementary medicine
Canella Claudia1, Wolfensberger Balz2, Witt Claudia M1
1Institute for Complementary and Integrative
Medicine; University Hospital Zurich and University of Zurich, Switzerland
2Institute of Education, University of Zurich, Switzerland
Objectives: This qualitative study aimed at analyzing patients’ experiences as well as their values, views and interpretive processes thatformed their perceptions of the use of a liquid extract preparation ofAngelica archangelica. The study provides insights into how Angelica
archangelica is currently used and experienced as a medicinal plantby Swisspatients.
Methods: Patients who routinely received Angelica archangelicaby their physician specialized in phytomedicine were included. They
filled in pre- and posttreatment questionnaires, kept diaries and wereinterviewed in a face-to-face setting. For data analysis, descriptive
statistics, qualitative content analysis, narrative inquiry and documentary method were applied. For this purpose, qualitative data analysis
software MAXQDA, version 11.0.11, wasused.
Results: A total of 13 patients with mainly gastro-intestinal complaints participated in this explorative, qualitative observational study.
Data collection comprised about 20 hours of audio- data, 379 transcript pages, 78 pages of diary and 26 questionnaires. First results show
a broad range of experiences attributed to the use of Angelica archangelica, from physical and sensory experiences to psychological, emotional and spiritual perspectives. Patients also report about dosage,
multimorbidity and comedication and reflect on changes in their daily
routines and personality.
Discussion: This is the first qualitative study of patients’ real-life
experiences with an ethanolic extract of Angelica archangelica. The
study provides an additional perspective on the use of Angelica archangelica as a medicinal plant.
Knowing about patients’ real-life experiences might provide guidance for a more individualized approach during treatment and forchoosing Angelica archangelica among several herbal ethanolic extracts that can be considered when treating gastro-intestinal complaints combined with states of weakness.

Correspondence to:Canella Claudia
E-mail: claudia.canella@usz.ch

138

BOOK OF ABSTRACTS | 12th European Congress of Integrative Medicine · 1st International Symposium on Integrative Health and Education

Title: Key Points for Establishing
and Implementing an Integrative
Medicine Service for Hospitalized
Patients
Elad Schiff1, Samuel Attias1 1Bnai Zion Medical
CenterObjectives: Integration of complementary medicine (CM) is common in ambulatory settings. However, integration in hospitals forin-patients is a relatively new phenomenon. In this presentation, I will
share key concepts on how to develop and implement an integrative
service in a hospital setting for in-patients.
Material and method: In this narrative presentation, I will present
the integrative service evolution at Bnai Zion Medical Center, in its
nine years of operation. I will focus on barriers and facilitators of integration on system and departmental level, safety issues, practitioner
experience, clinical protocol development, and the role of research.
Analysis: Narrative analysis of the various aspects of the service will
highlight themes associated with integration in hospitals.
Results: Key themes that evolved include practitioner selection;
medical and CM teams preparation phase; visibility & presence; establishing clinical and safety protocols; various roles of research; surprising routes of integration; and sustainability.
Conclusions: Providing CM for hospitalized patients is feasible andcan serve as an important leverage point for Integrative Medicine inhealth systems.

Correspondence to:
Elad Schiff
E-mail: elad.schiff@b-zion.org.il

Title: Integrative surgery: from minimum
invasion to maximum care
Elena Ortiz Oshiro1, Yari Aguilera Molina1, Rubendel Olmo Lopez1, Nestor Taboada Mostajo1, Pietro Giovanni Giordano1, Juan Carlos Meneu Diaz1
1Hospital Ruber Juan Bravo 49 Quironsalud Madrid
Objectives. “Minimum invasion” with all its variants has been imposed to a greater or lesser extent in the last 30 years, according toprocedures and hospitals, and has generated significant advantages inpatient recovery. Obviously, the refinement and the greater precisionof the techniques facilitate such recovery. But there are more factorsthat influence it. The objective of this presentation is to propose themovement of the focus from the technique towards the patient, incorporating the concepts of integrative medicine into surgery.
Proposal. Being able to further improve the results of surgery depends on changing the point of view of surgeons: from “organ” surgery to integral or “patient” surgery. From a global view of the patient,
the surgeon can create a therapeutic relationship from its inception,
which achieves: 1. In the preoperative period, a responsible, confident
and safe attitude that makes the preparations for surgery flow properly, and 2. In the postoperative period, minimise pain, inflammationand trauma associated with the intervention, and minimise the timerequired for complete recovery, using all possible means. This implies
the possibility of using natural medicine, relaxation and respiratory
techniques, yoga, homeopathy, mindfulness, acupuncture... all thisdepending on the training and experience of both the patient and thesurgeon, or the possibility of working in multidisciplinary teams.
Conclusion. We propose expanding the concept of minimal invasion
in all surgical specialties: beyond a less aggressive surgical technique, aharmonic patient-surgeon relationship, of integral collaboration, thatmaximises the possibilities of achieving an excellent postoperative period adapted to each patient.

Correspondenceto:
Elena OrtizOshiro
E-mail: eortosh@gmail.com

BOOK OF ABSTRACTS | 12th European Congress of Integrative Medicine · 1st International Symposium on Integrative Health and Education

Title: Viscum album: ideal complementary treatment in oncological immunotherapy
Juan Camilo Botero Gomez1
1Centro Medico Integrativo Dr Botters
The ideal cancer treatment is Immunotherapy (IT): the patient’s immune system selectively destroys cancer cells. Its effectiveness is conditioned by immunosuppression secondary to chemotherapy and/or cancer disease. Since 1920, the Viscum album has been used as
an immunomodulator, stimulating adaptive immunity (lymphocytes
infiltrating the LIT tumour) and innate immunity (dendritic cells) of
the patient, which translates into improving quality of life and survival
probability. Viscum is the ideal complementary treatment to IT, enhancing the LITs programmed by the tumour antigens exposed by IT,
rescuing the patient from the Escape phase to the Balance phase.

Correspondence to:Juan Camilo Botero Gomez
E-mail: botero@drbotters.com

139

Title: Brief analysis of theSport-Ginseng relationship, fromthe perspective of PubMed publications
Ramona Jurcău1, Ioana Jurcău2, Cornelia Popovici3, Mihai Kiss3
1Department of Pathophysiology, Faculty of Medicine, „Iuliu Hațieganu” University of Medicine andPharmacy, Cluj-Napoca, Romania
2Emergency Clinical Hospital for Children, Cluj-Napoca, Romania
3Department of Physical Education and Sport,
Faculty of Medicine, „Iuliu Hațieganu” UniversityoM
f edicine and Pharmacy, Cluj-Napoca, Romania
Introduction: Sport (S) and Ginseng (GSG) represent subjects ofresearch interest, but S-GSG relationship is, yet, modest investigated. The objective of the present paper was a brief analysis of theSport-Ginseng (S-GSG) relationship, from the perspective of PubMedpublications.
Materials and methods: S-GSG relationship was analysed in two
types of investigations. A) Comparative analysis for the keywords
combinations: Sport AND Ginseng (S-GSG), Sport AND Ginseng AND
Fatigue (S-GSG-F), Sport AND Ginseng AND Performance (S-GSG-P),
Sport AND Ginseng AND Endurance (S-GSG-E). B) Analysis for all
keywords combination, being evaluated the Sex filters, with corresponding sub-filters: male (M), female (F).
Results: The total number of S-GSG publications was 150, for a period of 35 years, since 1983, to date. % of publications from S-GSG is:
17% for S-GSG-F; 38% for S-GSG-P; 24.6% for S-GSG-E.
% of publications for M is: 63.3% for S-GSG, 40% for S-GSG-F, 54.3%
for S-GSG-P, 62.1% for S- GSG-E. % of publications for F are: 20% for
S-GSG, 8% for S-GSG-F, 21% for S-GSG-P, 13.5% for S-GSG-E.
Conclusions: 1) Number of PubMed publications for S-GSG has
an average of 4.2 publications per year, and the number of publications for 2018 is 7. 2) Of the S-GSG, most of the publications werefor S-GSG-P. 3) Most M publications were for S-GSG-E, and F publications were for S-GSG-P. 4) Studies on the S-GSG relationship, althoughnumerically reduced, are still increasing in recent years, covering theareas of interest F, P and E.

Correspondence to:Jurcau Ramona-Niculina
E-mail: ramona_mj@yahoo.com

140

BOOK OF ABSTRACTS | 12th European Congress of Integrative Medicine · 1st International Symposium on Integrative Health and Education

Title: Prooxidative effectsof sulforaphane in human
T cells: Beneficial in chronic
inflammatory diseases, but
potentially harmful in immunotherapy of cancer
Yvonne Samstag1, Jie Liang2, Jacqueline-Denise
Ziegler1, Katrin Hübner1, Norbert Blank3, Gertrud
Maria Hänsch1
1Institute of Immunology, Section Molecular Immunology, Heidelberg University, Heidelberg,
Germany2Institute of Immunology, Section Molecular Immunology, Heidelberg University, Heidelberg,
Germany (present address: )Institute of Immunology, Qingdao University, Qingdao, China) Instituteof Immunology, Section Molecular Immunology,
Heidelberg University, Heidelberg, Germany
3Department of Rheumatology, Heidelberg University, Heidelberg,Germany
Many cancer patients use complementary medicine including dietary supplements in addition to conventional antitumor therapies.
Among those is sulforaphane (SFN) derived from plants of the Brassicaceae family. SFN has been reported to be chemopreventive, toinduce tumor cell death and to improve the efficacy of chemotherapeutic drugs. However, little is known about effects on T cells, which issurprising because T cells play a crucial role in tumordefense.
Using advanced methods of biomedical and immunological research, we studied the effects of SFN on primary freshly isolated human T cells. We found that in human T cells SFN increases the concentration of reactive oxygen species (ROS), and reduces the level of thecellular antioxidant glutathione. Such a prooxidative milieu selectively
suppresses T cell activation. This newly discovered immunosuppressive effect of SFN could explain the rather low therapeutic benefit
of SFN seen in clinical trials with cancer patients. On the other hand,
our data reveal that SFN may be beneficial in T cell-driven chronic inflammatory diseases such as rheumatoid arthritis (RA). T cells fromRA patients show reduced ROS production, and thus develop into
interleukin 17 producing T cells (Th17) that play a central role in theinitiation and progression of inflammatory diseases. We found thatthe transcription factor STAT3 that critically regulates the expressionof Th17-related genes is a major target of oxidation in T cells. Testing
the effects of SFN on whole blood from RA patients indeed revealed
an increase in ROS levels in lymphocytes as well as a markedly decreased production of proinflammatory Th17-related cytokines.
In conclusion, SFN may be a promising immunosuppressive substance for the treatment of Th17- related chronic inflammatory diseases such as RA. However, intake of SFN may be counterproductive incancer patients, at least during T cell-based immunotherapies (e.g.
checkpoint inhibitors or CAR T cells).

Correspondence to:
Yvonne Samstag
E-mail: yvonne.samstag@urz.uni-heidelberg.de

Title: Maternities. Woman and creative
will
Manuela Cuevas Expósito1 1MD, Ginecologa, Barcelona
JUSTIFICATION
Fertilisation in the laboratory specimen expresses the maximum
dissociation of sexuality and reproduction. This binomial until morethan half a century ago was inevitably linked. Separating sexuality andreproduction was one of the milestones in the feminist struggle. The
appearance of the pill, the use of different contraceptive methods helped to make it possible.
However, in this dissociative essay we are losing focus. Today women are no longer slaves to their reproductive system. They haveleft it behind... Immersed in the world of the intellect, split from theirbody.
When they consider becoming a mother, it is one of the momentsthat turns their gaze to their uterus. In this communication I would liketo make an approach to motherhood through the analysis of 5 casesthat came to my office due to infertility/subfertility problems.
OBJECTIVES
To show the interrelation of the causes of infertility according to theplane in which they act (functional, physical,psychological...).
To publicise the effectiveness of integrative medicine in the cure ofthese healthproblems.
To present graphically the imbalance in women with this problem
from the diagnosis of AnthroposophicalMedicine.
MATERIAL AND METHOD
Analysis of 5 clinical cases treated in my office.
Investigate the concept of the invisible man/woman in us, the fieldof anthroposophical medicine. RESULTS AND CONCLUSIONS
Separating sexuality and reproduction requires a process of consciousness and transformation in women to avoid body/minddissociation.
The creative force of the uterus (CREATIVE WILL) if it is not transformed/integrated can cause pathology that can be expressed in thephysical or functional plane. Many cases of idiopathic infertility arerooted in thisdissociation.
Working these imbalances from integrative gynaecology can help
women as an alternative to assisted reproductionprograms.

Correspondence to: Manuela Cuevas Expósito
E-mail: artemisamc@hotmail.com

BOOK OF ABSTRACTS | 12th European Congress of Integrative Medicine · 1st International Symposium on Integrative Health and Education

Title: Healthy parents, Healthy children. Healing the next generationby using the purest ingredients: Superfoods, Homeopathy and Biofield
therapy
Biljana Uzelac, MD1
1Green Pediatrics Integrative Clinic
Objective: To show that chronic and autoimmune disease can be
managed and in some cases reversed solely by using custom tailored
diet, homeopathy and Biofield therapy.
Introduction: ASD (Autism Spectrum Disorder ) is wide spread (1in 50 kids affected) and PANS/PANDAS (Pediatric Autoimmune Neuropsychiatric Syndrome +/— associated with Streptococcal infections)
is just getting more recognized
as a disease in kids.
Methods: Children diagnosed with varying types of behavioral disorders were evaluated weekly by their parents on a variety of behaviors. Initially, children had a basal evaluation on the following attributes: Focus/Attention, Communication, Mood, Memory, Tantrums,
Aggression, Appetite and Tics. Following initial scoring, children enrolled in the study age 6-14 (total 33 subjects, 22 boys and 11 girls)
were given a titanium patch (sticker) charged with extremely low
Electromagnetic frequencies beneficial for brain function, and they
wore it for a seven-day period. After the first 7 days, behaviors were
evaluated and a new patch was applied for another 7 days. This was
repeated for 7 weeks. At week 3 homeopathic medicines and supplements were added.
Results: Our study showed obvious improvement in behavior after
2 weeks of wearing the patch and not returning to the baseline after
patch was removed. Adding specialized nutrition and supplements
as well as homeopathy to the initial patch therapy further improved
behavior results. Conclusion: Children suffering from ASD, ADD and
PANS/PANDAS improved dramatically their behavior and communication, lessened anxiety, become more social and engaging, and lesssensitive to the environment after wearing low electromagnetic frequency patch and further more improved after adding supplements, anti-inflammatory diet and homeopathic medicine in their therapy
without returning to theirbaseline once all treatment was stopped.

Correspondence to:
Biljana Uzelac, MD
E-mail: doctor@greenpediatrics.com

141

Title: Establishing Integrative Care forChildren with Cancer – The Nurse Perspective
Wiebke Stritter1, Britta Rutert1, Alfred Längler2,
Christine Holmberg3, Georg Seifert1 1Charité Universitätsmedizin Berlin
2Witten/Herdecke University
3Brandenburg Medical School Theodor Fontane
Introduction
While prognosis in pediatric oncology is improving through achievements of modern medicine, patients are suffering from multiple side
and late effects. To ease the associated suffering external applications
as used in anthroposophic medicine and care have shown to be usefulin ameliorating nausea, abdominal pain and sleeping problems.
An integrative care concept based on anthroposophic medicine
was implemented at a pediatric oncology ward at a German university hospital. Leading question of this contribution is the perspectiveof the nursing staff on in integrative care and the implementation process.
Methods
We conducted problem centered interviews with nurses at the pediatric oncology ward before and after the one-year implementation
period. In addition we carried out a focus group discussion with a coreteam of nurses that specialized in integrative care throughout the implementation period.
The transcripts of the interviews and focus group were analyzed
according to thematic analysis. Core categories were identified andfurther analyzed.
Results
In the beginning reservations were expressed by the nursing staff
regarding lack of time for training and realization of the new integrative care interventions. Through the course of the implementation period the core team that specialized in integrative care developed confidence in applying the new skills and assertiveness in their new role.
All members of the nursing team noticed the positive feedback ofpatients and parents. In combination with the experience that the
new interventions are not as time-consuming as suspected they even
now wish for further training within the team.
Discussion/ Conclusion
The attitude towards the integrative care concept within the nursing team shifted over the time of the implementation period. The
next challenge is to sustain the grown positive attitude and to keep
the integrative care concept alive.

Correspondence to:
Wiebke Stritter
E-mail: wiebke.stritter@charite.de142

BOOK OF ABSTRACTS | 12th European Congress of Integrative Medicine · 1st International Symposium on Integrative Health and Education

Title: Education of feelings through flowers
Yukiko Inao1, Carla Pontecorvo1, Haydee Recasens1, Marta Graciela Gallo1, María Celia Monserrat1, Flavio Moreno1
1MOA Internacional
Introduction: In our Clinic in Buenos Aires where we work with Integrative Medicine, Floral Arrangement workshops are held as partof the Comprehensive Health System. Creating a floral arrangementwith serenity and tranquillity offers a positive influence to the mind.
Objective: Descriptive/comparative work, consisting of assessing
the emotional and behavioural impact on children after creating afloral arrangement.
The drawings made before and after the floral arrangement werecompared.
Material and method: A flower arrangement workshop held at the26th Primary School of the City of Buenos Aires with 7 girls and 10
boys aged between 9 and10
Another workshop in Primary School 3. 61 students from 7-13 years
old participated. 29 girls and 32 boys
Vases made with recycled material, natural flowers and branches invases were placed on a table.
First they were invited to create a free drawing on white paper withpencils. The second drawing was completed after the FloralArrangement.
The task was to take a flower that they liked, take it to its place toobserve, feel and enjoy it, choose a vase, and create the arrangement
to theirliking.
Analysis: The drawings made before and after the floral arrangement were analysed. Results:
In school 26: The most relevant conclusions were the following: 9
out of 17 showed signs of aggressiveness in the first drawing, in thesecond, 5 of the 9 participants improved the strokes showing moreease, more joy.
In school 3: There was a positive impact and changes in the second
drawing in 79% of the girls and 55% of the boys.
Conclusions:
The comparison of the drawings certified the change of mind of theparticipants when making the floral arrangement. The drawings had
more colour, more complexity and joy and it follows that the flowers
induced positive feeling

Title: The effects of Thoracolumbar
Fascia Taping on posterior capsuletightness in patients with Subacromial
Impingement Syndrome
Nihan Ozunlu Pekyavas1, Kubra Sarioglu1, Gul
Baltaci2 1Baskent University
2Private Guven Hospitals
Objectives: Posterior capsule tightness of the shoulder joint is an
important factor affecting both incidence and prognosis of subacromial impingement syndrome (SAIS). The first recommendation of
the treatment of SAIS is to reduce posterior capsule tightness. Another newly found factor affecting SAIS is the hipomobility of thoracolumbar fascia. There are studies in the literature about treatmentof SAIS by taping to decrease pain and improve function. But yet, no
studies have been found about the effects of taping thoracolumbar
fascia correction technique on posterior capsule tightness in patientswith SAIS. Material and method: A total of 30 volunteer patients (Age
X±SD: 24.83±7.10, BMI X±SD: 22.91±5.14) with SAIS were included inour study. Posterior Capsule Tightness was measured with tape measurement for the flexibility of posterior capsule region.
Kinesio Taping Fascia Correction Rams Head Technique was appliedon the contralateral thoracolumbar fascia region with 25-50% tension applied to the tape. Assessments were done before and 45 minutes after taping application. Analysis: SPSS 21.0 statistics package
program was used for statistical analysis. Wilcoxon Test was used toanalyze the difference between pre-post taping application results. All
statistical analysis was set a priori at an alpha level of p<0.05.
Results: Statistically significant differences were found at posterior
capsule tightness results for dominant (p=0.060) and nondominant(p=0.001) sides between before and after treatment.
Discussion: Taping application for thoracolumbar fascia correction
may be an effective method for reducing of posterior capsule tightness and thus affecting the treatment of SAIS. Conclusions: Treating
thoracolumbar fascia is also a condition to be considered for treatment of SAIS as well posterior capsule tightness.

Correspondence to:
Nihan Ozunlu Pekyavas
E-mail: nihan_2002@hotmail.com

BOOK OF ABSTRACTS | 12th European Congress of Integrative Medicine · 1st International Symposium on Integrative Health and Education

Title: A novel highly effective and simple
face-lifting procedure for beauty acupuncture
Tamae Hera1Ryota Fujiwara2 1Oriental Treatment Clinic Etre 2Sun Park Nakanoshima Clinic(Background)
In recent years, more and more people have an interest in healthand beauty. Therefore, the needs of beauty acupuncture are also increasing.
However, there are very few beauty acupuncturists due to the difficulties of mastering beauty acupuncture techniques.
As such, the author proposes a novel simple treatment for face-lifting. (Objective)
This study was undertaken in order to confirm the effectiveness of anovel simple face-lifting procedure for beauty acupuncture.
(Method)
Press tack needles were used as acupuncture needles. 14 subjects(5 men and 9 women) were studied.
All are acupuncturists. They treated each other in pairs. This treatment was carried out as training to learn theskills.
The needles were attached on the following acupoints of the meridians. These selected points are as follow,
1) GB13: Honshin, 2) GB15 : Rinkyu, 3) TE23: Shichikuku, 4) Ex-HN4:
Gyoyou,5) BL2: Sanchiku, 6) Ex-HN3 : Indou, 7)ST6:Kyousha,
8) ST5:Daigen,9) ST7: Gekan, 10) ST18 : Kenryou, 11) LR3: Taishou, 12) K13: Taikei,
13) ST36: Ashi-Sanri (Results)
An observable face-lift effect was seen in 13 of 14 persons. Our
study almost had 92% reproducibility for this treatment. Among the
13 people, their faces became more firm.
Furthermore, asymmetrical facial distortions of thin muscles suchas front face muscles and masticatory muscles in 11 cases were improved through the procedure.
(Discussion)
An observable face-lift effect was found in 13 of 14 subjects. This
demonstrates that our novel simple face lift technique has high reproducibility.
Conclusion
The proposed novel simple beauty acupuncture technique is effective for face-lifts.

Correspondence to:Tamae Hera
E-mail: ra678tae@etre1.com

143

Title: Depression: Evidence in structural
neuroimaging
Santiago Contreras1
1 Independent investigator

From its dawn, the science demonstrated the indications of themind/body relationship. We intend to demonstrate that the Depressive Syndrome belongs to psychosomatic diseases. We have evidenced
images that justify that said mood disorder is a consequence of systematicstress.
We worked with around ten already diagnosed patients whose
diagnosis evolved without response to the treatment of Psychiatry
and who, in their medical history, reported some degree of frustration regarding the effectiveness of the treatment. The premise of thework consisted in evidencing the psychic trauma as the aetiology ofthedisease.
Brain tomograms were interpreted, compared with the patient’s
clinic practice, and a neuroanatomic/etiological relationship was discovered, allowing us to use a new theoretical framework that differsfrom the orthodox model.
It was concluded that it is imperative to review the epistemologicalnature of knowledge to write new foundations and elaborate on the
rigour of scientific language, solid arguments that allow us to defend
the most important points of this proposal. We hope that, in the near
future, this model may become an alternative for diagnosis and possible therapeutic approach, trying to overcome the closure that tarnishes this scourge that disrupts the life of any human being without
distinction ofage.
Correspondence to:Santiago Contreras
E-mail: santiagocontreras2019@hotmail.com

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BOOK OF ABSTRACTS | 12th European Congress of Integrative Medicine · 1st International Symposium on Integrative Health and Education

Title: The most prevalent healthburdens in subjects diagnosed
with respiratory system ailments
found by bioresonanceAntonina Rome1, Tanja Misic2, Dusan Vesovic3
1Institute for Bioresonance and Regulative medicine, Ljubljana, Slovenia
2Military Medical Academy, Belgrade, 11.000,
Serbia3VISAN -- Sanitary Medical School of Applied Sciences, Belgrade, 11.000, Serbia
Background
Bioresonance therapy has become widely used approach in healing
patients in integrative medicine. Objective
The aim of the paper was to present the presence of various healthburdens in subjects diagnosed with respiratory system diseases (RSD).
Materials andmethods
130 patients of both gender were included in the study (48 – 36,9%
males, and 82 – 63,1% females). Mean age was 42,6+-8,9yrs. They filled out questionnaire related to presence of diseases in accordance
to International Classification of Diseases 10 (ICD-10). Afterwards they
were tested with german bioresonance therapy apparatus. Statisticalanalysis was done by using SPSS v. 17.0. Results anddiscussion
Of 130 subjects enrolled into study, 43 (33,1%) were diagnosed with
RSD. Bioresonance testing revealed presence of following health burdens in these subjects: Helicobacter pylori was present in 18 (94,7%)
subjects; the same prevalence was found for mercury and lead intoxication. Pork meat intolerance, Aspergillus, and aflatoxin were revealed in 17 (89,5%) subjects. Gluten and sugar intolerance, presenceof Candida, Oxyuris, formaldehyde and aluminum intoxication were
found in 16 examinees (84,2%), while Staphyloccocus, Ascaris and zinc
deficiency were revealed in 15 (78,9%) subjects enrolled in analysis.
Conclusions
The most prevalent health burdens revealed by bioresonance inexaminees diagnosed with RSD were presence of Helicobacter pylori, mercury and lead intoxication. Other important factors that may
be associated with respiratory system diseases are pork meat intolerance, Aspergillus, aflatoxin, gluten and sugar intolerance, Candida,
Oxyuris, formaldehyde, aluminum, Staphyloccocus, Ascaris, and zinc
deficiency. Bioresonance is very useful method in identifying healthburdens and may help to diminish them.

Correspondence to:Antonina Rome
E-mail: info@institut-brm.si

Title: Importance of Āhāra
(diet), Āhāra-vidhi vidhāna (dietary guidelines) and (digestiveAngipower) for maintaining healthylife
Dr. Shivaranjani kantharia1 1J.s. ayurveda college,nadiadĀhāra (Food), Nidrā (Sleep) and Brahmacarya (Abstinence) are
the three factors which play an important role in the maintenanceof the health of a living organism, thus are termed as sub-pillars(Upastaṁbha) of the physiology of the human body. The inclusionof Āhāra (Food) in the three upastaṁbha proves its importance. In
this present era, in a very fast and competitive life, people do not follow the proper manner of diet and consumes junk food, incompatible food and contradictory foods which produce negative outcome
on health. Mental and emotional states are also influenced by thedigestion of food. People who take healthy and hygienic food but ifthey have any kind of mental disturbance, their food doesn’t digest
appropriately and they have not to get proper nutrition. The ancient
Ayurveda ācāryas have given “Āhāra and Āhāravidhi vidhāna” (DietandDietary guidelines) in which they tremendously described why(importance of food), how (proper methods of food consumption),when (timing of consuming food), where (place of eating) and whichtypes of food is consumed for maintaining the health in healthy individuals as well as for relieving disease in illperson.
Here there is an effort to elaborate the knowledge about the ayurvedic concept of “Āhāra, Āhāravidhi vidhāna and role of Agni” in digestion and nutrition and its importance for maintaining healthy state, the effects of Pathya āhāra (wholesome food) and Apathya āhāra
(unwholesome food)on the body and mind, health issues emerges
due to the consumption of Viruddha Āhāra (incompatible food).
BIBLIOGRAPHY
1.
Agniveśa. Caraka Saṁhitā with ‘Ayurveda Dīpikā’ Commentary by Cakrapāṇī- Editedby Acharya YT, Chaukhambha Surbharati
Prakashan, Varanasi- 221001,2013Suśruta. Suśruta Saṁhitā, ‘Ayurvedatattva sandīpikā’ Hindi commentary by Shastri AD, Chaukhambha Sanskrit Sansthan, Varanasi221001,2014
Vāgbhaṭa. Aṣṭāṅga Saṁgraha, hindi commentary by Gupta A, Part-I, Chowkhambha Krishnadas Academy, Varanasi – 221001,2011

Correspondence to:
Dr. Shivaranjani Kantharia
E-mail: shivaranjani2004@gmail.com

BOOK OF ABSTRACTS | 12th European Congress of Integrative Medicine · 1st International Symposium on Integrative Health and Education

Title: Simple novel symmetric acupuncture therapy with 7 press needles is effective for muscle pain and stiffness
Ryota Fujiwara1, Tamae Hara2 1Sun Park Nakanoshima clinic 2Oriental treatment clinic Etre
(Background)
Acupuncture treatment seems difficult to perform, because there
are so many invisible acupoints. In addition, treatments depend ona patient’s condition, so there are so many variables. This situation
presents difficulty for acupuncture.
The author proposes a novel simple technique. It uses only 7 press
needles. (Objective)
This study was undertaken in order to confirm the effectivity of thesimple novel symmetric acupuncture therapy for muscle disturbances.
(Method)
Press needles are used as the acupuncture needle. Acupoints are
selected in symmetrical positions. Treatmentstepsforcorrelatingacupointsareasfollows. Step 1: foot:Koukan(LR 2):R&L(2poits)._
Step 2: arm:Kyokuchi(LI 11): R&L(2poits)._ Step 3: knee:Kekkai(SP10): R&L(2poits)._ Step 4: sacral:Youyu: (GV2) : Center(1point)
Total: 7 points (Result)
Patients had several muscle problems such as muscle pain, muscle
stiffness and joint movable range limitations.
This therapy has made their problems better. The symptoms got
better soon after treatment.
In most cases, the symptoms had already changed when the 7th
press needle attached the acupoint. (Discussion)
This therapy has several positive effects. Especially for muscle pain
and joint movable range limitations, they clearly and quickly improved.
This novel therapy needs a very short time to take effect. It takes
only 1-2 minutes. It is simple and effective.
Several acupoints (LI 11._SP10) are located on tendon areas. This
fact seems to be the cause of the effectiveness of muscle pain andstiffness.
(Conclusion)
The author proposed a novel acupuncture method. It is simple symmetrical acupuncture with 7 press needles. This method was effectivefor various muscle disorders.
Correspondence to:
Ryota Fujiwara
E-mail: fuji23ryo56@gmail.com

145

Title: Clinical Thermography applied to
Health Sciences
Pedro Rodríguez Picazo1
1Medintegra
Introduction
Clinical thermography is a physiological imaging technology thatprovides information on the functioning of various body systems andsubsystems as well as local inflammatory processes. When used in aclinical setting, it is an imaging procedure that detects, records andproduces a thermogram of the skin’s surface temperatures and thermal patterns. The objective of this work is to describe the clinical experience and the scientific basis of saidtechnology.
Material and method
A clinical image bank review of the consultation and bibliographic
review with various pathologies and their corresponding correlations
is carried out.
Results and Discussion
Findings that correlate acupoints and kinetic chains are described(Wang et al 2019). The literature has also described some utility inpreventing phlebitis in peripheral catheterisation during hospital admissions (Doesburg et al 2019). Bahramian et al (2019) describe areduced sample universe experience in thyroid lesions. Advances ofthermography in the field of Veterinary Medicine (Pérez Marquez etal 2019-Wats et al 2019-Redaelli et al 2019) and in Motion Sciences
are reviewed.
We describe the limitations of the technology (Pérez Guarner et al
2019-Omranipour et al 2016- Neal et al 2018- Ferreira et al 2019 -Kalaiarasi et al 2018).
The thermogram allows, among other things, to assess:Approach and trigger point treatments Biomechanical and posturology study Visualisation of certain organ-visceraldysfunctions
Images obtained in consultation with clinical implications are reviewed Conclusions
Clinical thermography can contribute to the diagnosis and management of the patient, helping to determine the location and degreeof irritation, the type of functional disorder and the prognosis of thetreatment. Thermography is a discipline with important advantages
and low cost without involving the use of ionizing radiation, venous
access or other invasive procedures

Correspondence to:
Pedro Rodríguez Picazo
E-mail: medintegrasalud@gmail.com

146

BOOK OF ABSTRACTS | 12th European Congress of Integrative Medicine · 1st International Symposium on Integrative Health and Education

Title: Bioenergy Healing within the Comprehensive Patient Care
Tomas Pfeiffer1
1Professional Chamber Sanator - the Union of
Biotronicists of Josef Zezulka
Although this contribution seemingly does not speak the language of modern science, it does not mean it is unscientific. Numerous
opinions previously presented by Josef Zezulka Biotronics were later
confirmed by science and the method brings visible benefit.
Healing is performed by vital immaterial energy transmitted by abiotronicist. It influences illnesses originating from bioenergy insufficiency, without any invasion and side effects. Monitoring of thepatient’s state enables its research. Exceptional results are achievedin oncological and neuro- degenerative diseases, especially sclerosis
multiplex, infant cerebral palsy etc.
A great potential lies in the area of prevention and cooperation
with medicine. The method is guaranteed by a professional chamber.
Similarities to some Indian systems of medicine can be identified.
Selected cases:
A patient (aged 53) – melanoblastoma on a shank. After unsuccessful four-year surgery and chemotherapy treatment the tumour spread
into the abdominal area. Then biotronics healed the patientfully.
A dying patient (54) – an inoperable stomach tumour, a palliative
surgery conducted – tumour abridgement, small intestine resection,
the tumour left in its location. The patient was released to home carewith 2-3-month life expectancy. After biotronic healing she recovered
completely and lived a full life for 23years.
A dying patient (70) – malignant tumour of the right upper pulmonary lobe. The patient was released home after unsuccessful chemotherapy and left without any medical treatment. After a biotronic intervention she recovered completely and lived for 13years.
131 patients’ reactions to biotronic healing, e.g. breast carcinoma,skin melanoma, pulmonary cancer with multiple metastasis, uterus
myoma, sclerosis multiplex, thyroid gland autoimmunity hyperfunction, arthritis, pulmonary mycobacterial avium,etc.
The Czech Republic neglects non-medical branches, conducting a
trial is impossible despite considerable interest of the public in biotronic healing performed free of charge in the Biotronic Centre for Social
Support in Prague.

Correspondence to:Tomas Pfeiffer
E-mail: info@sanator.cz

Title: An exploration into the impact of
cultural health perceptions and traditional medicine approaches on dietaryintake of BME populations in the UK
Anne Majumdar1, Pearl Braithwaite1 1St Mary’s
University Twickenham
BackgroundBlack and minority ethnic (BME) communities are at increased riskof chronic disease and dietary intake can influence this risk. Cultural
health beliefs and practices, including traditional medicine approaches, are commonly held by BME communities and may impact on
their dietary intake. The focus of this study is to explore the cultural
perceptions of barriers to healthy eating from BME populations livingin the UK.
Methods
A mixed methods design, using a short online survey tool to analyse
perceived cultural barriers and general nutritional knowledge in thequantitative study phase. Survey respondents were invited to attend
an interview or focus group where perceptions of the phenomenon
were further explored in the qualitative approach of this study. Transcripts from interviews and focus groups were analysed using IPA. Ethical approval was received from St Mary’s University ethics committee.
Results
The survey was completed by n=134 participants from BME backgrounds (African, Caribbean, South Asia, East Asia and South East
Asia). 79% of survey respondents “agreed“ that cultural factors influenced uptake of healthy eating messages within their BME group.
N=28 participants joined focus groups (n=13) or interviews (n=15).
Three super-ordinate themes emerged, “acculturation”, “drivers ofchange” and “education “. Traditional medicine beliefs impacted onfood choice and a prevalent emergent theme was the need for an ambassador from the same cultural community to drive change, teachand influence others to adopt healthier eating practices.
Conclusion
Results highlighted the need for evaluated, well designed and culturally tailored nutritional interventions for BME populations living in
the UK. Findings from the study indicate that further research on ahealth model where health professional’s work with BME community
ambassadors to educate, implement and drive behavioural change iswarranted.

Correspondence to:Pearl Braithwaite
E-mail: pearl.brathwaite@diabetes.org.uk

BOOK OF ABSTRACTS | 12th European Congress of Integrative Medicine · 1st International Symposium on Integrative Health and Education

Title: Biophisic and Epigenetic: new paradigms for preventive and predictive medicine
Antonio Scalabrino1
1Prof. Dott. doctor surgeon,,odontologist, posturologist, clinical nutritionist, master in mesotherapist, university professor
In the twenty-firs century new methodologies and new technologies allow to analyze and predicted in advance form of systemic
and invalidating phatologies to which we are predisposed, while theknowledge of medical biophysics allows through quantum biophysical semeiotics with the only phonendoscope, after a normal learning
cure, to understand the form and function of varius organs and tounderstand the predisposition to possible oncological terrain. If we
associate this methodology to Epigenetics we can truly prevent andpredict the diseases and health status of each individual. The classic
medicine of ANTI (antibiotics, antihistamine, anti-inflammatory, antihypertensive, etc) is no longer enough to understand if an organism ishealthy, the concept of healthy should not be interred as the absenceof signs and synths, but the perfect functioning of all cell, organs andsystem of our body. We live, we move due to differences in electric
potential, there was no difference in potential, we would be flat or
we would not exist. Our Body is a billions matter and the rest is energy(Spaggiari-Stagnaro) and the analysis of this energy through the resonance frequency allows us to understand if our internal organs arehealthy or sick, long before an exam biochemist tell us that we have ananomaly.In the same way epigenetic examinations of hair,saliva andfaeces can analyze the genetic variant the each of use, can really talkabout primary and interceptive prevention with a biological cost at
zero.

Correspondenceto:
AntonioScalabrino
E-mail: studiodottscalabrino@gmail.com

147

Title: How the Idea of Boundaries Helps
Us to Understand Our Patients as Embodied Human Beings: A Literature Analysis of Psychosomatic Foundations andthe Concept of Embodiment
Juliane Walther1
1International Psychoanalytic University Berlin
Aim
During the last years the concept of embodiment became a key
paradigm of interdisciplinary theoretical approaches of philosophy,
psychology and neuroscience (FUCHS 2009). But despite its incredible
potential, it isn’t completely integrated in medical theories or practices. Working with patients means working with bodies: Theirs andours. This can be very exhausting, sometimes leading into burnouts.
Why is that? For answering that it is necessary to take a step back: Since the condition of the practice is so decisively affected by the theory,
this leads to a theoretic question: Is there a difference between the
bio-psycho-social medicine understanding of the body in comparison
to conventional medicine – and with which implications?
Methods
This question is addressed to the basic theory of Thure von Uexküll and pursued by means of a comparative and summarizing content
analysis of his publications. Based on the results from a reconstruction, the analysis has been deepened by adding the phenomenological concept of embodiment.
Results
The analysis shows that the initial question has to be answered inseveral stages: 1) Uexküll does not overcome the conventional understanding of the body, but expands it to include conceptual levelsof functionality.
The body lives in unity with the environment and extends into it. 2)
The phenomenological body is also extended into the environment
via its exterior. 3) This raises the question of boundaries.
According to Plessner, these can not only be understood as conclusive but, understood with Uexküll, also as enabling coexistence.
Understanding the body as a lived one, it cames up with phenomenological boundaries.
Conclusion
Boundaries, especially phenomenological ones, turn out to be aquite practical mental concept to understood patients as embodied
humans – and yourself, too. It can be used to explore methods of selfcare and empathy.
Seven types of possible handling are presented.

Correspondence to:Juliane Walther
E-mail: juliane.walther@ipu-berlin.de

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BOOK OF ABSTRACTS | 12th European Congress of Integrative Medicine · 1st International Symposium on Integrative Health and Education

Title: Incorporation of Holistic Medicine
into academic healthcare setting
Chiti Parikh1
1Weill Cornell Medical College
An integrated care model combines evidence based conventional
medical approach with holistic modalities to address not just thephysical symptoms but also the psychological, social, spiritual andenvironmental influences on health. Three years ago we created theIntegrative Health and Wellbeing program to bring evidence based
holistic modalities into academic healthcare setting.
When we began this venture, we took a great deal of time to learn
how others had developed and sustained similar programs. We visited established Integrative Health programs around the country, andmet with leaders in the field and who are actively expanding the footprint of the integrative approach in the U.S. and globally.
We thought it equally important to understand our own institution and the patients we would soon serve. Through our process of
discovery, we applied what we had learned into a new model, andlaunched The Integrative Health and Wellbeing Program at New York
Presbyterian Hospital in 2015. This program offers services such as
physician consultation, nutrition, psychotherapy, Ayurveda, functional medicine, acupuncture, meditation, yoga, reiki and pilates. These
services are offered alongside conventional medical plan in a team
based approach.
In our first year of operation we saw 4000 individual patient visits
and this year year we are on track to see over 10000 patients. By embracing an insurance based model, along with creative program offering we have made integrative modalities accessible, affordable andsustainable. There are several elements that have been integral to ourearly success: stakeholder engagement,
strategic planning, organizational structure and operations, marketing and communications, building performance metrics, and building
our team. We would like to share some of these lessons we have learned along the way. We hope this knowledge can help other cliniciansand healthcare institutions create successful and sustainable programs by embracing a more holistic care approach to care.

Correspondence to:Chiti Parikh
E-mail: chiti9@gmail.com

Title: Health Beyond Healing: A course
to activate Salutogenesis by building
Somatic Sense of Coherence
Daniela Jurisic1
1Medical College of Wisconsin and Aim for Health
Clinics in Pavia and Milano
A person who is no longer ill, but not yet robustly healthy, is in an
important transitional zone which is common ground for treatment
by a great diversity of integrative health professionals, from allopathic
doctors to yoga teachers. The common goal needs to be to provide salutogenesis, the ability to maintain and reinforce one’s own health. Inorder to activate salutogenesis, a person needs to maintain a sense ofsomatic coherence: to be aware of the changes that a treatment or aphysical practice induces, in order to choose and activate themselves
appropriately to absorb the salutogenic practice that is beingoffered.
Accordingly, I have designed BASIC (Body as a Source of Identification and Coherence), a course that helps patients anchor future health practices in accurate somatic perception. “Coherence” is acquired
through the linking of exteroception, information received throughthe 5 senses, with interoception, information perceptible by each person, from their internal organ systems (for example lungs, gastrointestinal tract, cardiovascular system, autonomic nervous system)
5 lessons : each one targets accurate perception of a specific interoceptive sensation, through an exteroceptive “access point”. Exteroception and interoception are thus linked: first, through explanationof the functional anatomy and physiology of the access point and thenthrough exercises which train somatic perception of this linkage. This“body mindfulness” which is acquired, allows the development ofsense of agency necessary for personal salutogenesis.
This course is designed for all integrative professionals and their patients. I will present an outline of the exercises and results obtained inteaching it to 15 professionals and more than 100 patients.

Correspondence to:Daniela Jurisic
E-mail: danielajurisic@hotmail.com

BOOK OF ABSTRACTS | 12th European Congress of Integrative Medicine · 1st International Symposium on Integrative Health and Education

Title: Together in Integrative Medicine - A New Multi-Professional
Diploma Training in Integrative
Medicine
Dr Elizabeth Thompson1, Dr Duncan Still1, Alastair
Gray1, Pat Turton1 1National Centre for Integrative Medicine (NCIM) - Bristol, UK
Background:With enthusiasm to adopt an Integrative Medicine (IM) Modelby healthcare professionals and to reflect and support the public’s
growing interest in Health and Wellbeing, the National Centre for Integrative Medicine (NCIM) has developed a two year, Masters Level 7
Diploma in IM.
Methods:
We describe the development and implementation of this new,
two year Masters Level 7 Diploma in IM to give registered healthcare
professionals the knowledge and experience they need to become
Integrative Clinicians who can support individualised and comprehensive whole-person healthcare plans for their patients and createa necessary sea-change in healthcare provison.
Results:
In the face of numerous challenges, we have developed a 1200hour, 120-credit, regulated, two-year qualification in IM. The course
is a blended model of learning that is delivered via an online learning
platform with expert multimedia content, as well as face-to-face study
blocks (‘intensives’) and other models of student engagement including tutorials, webinars and other resources within the Learning Management System.
Conclusion:
Healthcare professionals from around the world have signed up forthe course in increasing numbers suggesting a growing awareness of,and desire to train in, IM and to transform existing models of healthcare provision. Feedback from our learner group has been extremely positive although some have struggled to keep pace with theamount of educational content combined with their working schedules. The students are fast becoming pioneers in the field of IM andare themselves now supporting a transformation to comprehensive
whole-person care. We want to share our learning on how to set up
and run such a programme.

Correspondence to:
Dr Elizabeth Thompson
E-mail: elizabeth.thompson@ncim.org.uk

149

Title: Re-engineering the Health System
for South African traditional healthcare
Torkel Falkenberg1, Renee Street2 1Karolinska Institutet
2South African Medical Research Council (SAMRC)
Background: The UN Sustainable Development Goals do not include the millions of complementary and traditional health care practitioners contributing to health care around the clock for millennia.
To consequently omit health seeking behaviour and user confidence
involving billions of people is effectively medical apartheid. The Nobel
prize for the antimalaria drug artemisinine from traditional Chinese
medicine, has saved millions of lives, attesting to its potentiality, albeit risks with traditional medicine are inherently obvious. The WHO
global strategy for Traditional Medicine emphasize the need to develop a cohesive and integrative approach to health care that allows governments, health care practitioners and those who use health careservices, to access traditional and complementary medicine in a safe,
cost-efficient and effective manner. Objectives: In the international
research project “Re-engineering the health system for South African
traditional healthcare (REHSAT)” we aim to investigate based on theprinciples of integrative medicine, in what capacity the circa 200 000
THPs can better support the health system while simultaneously providing services for seekers of indigenous health to improve collaboration in primary health care. Problem description: South African isoverwhelmed by HIV and AIDS and TB, maternal infant and child mortality. In 2009, the Lancet series on Health revealed that South Africa
spends more on health than any other African country. Yet health indicators for South Africa are deteriorating and the health sector reform
Re-engineering Primary Health Care has been initiated. Material andmethod: A multidisciplinary approach including Cochrane systematic review, policy and legislation research; qualitative interviews andstakeholder analysis. Results and Discussion: Interim results including
barriers and opportunities will be presented and the basis for future
pragmatic pilot trials of models of integration adapted to a South African context in line with Swedish experience, CAMbrella methodology
and WHO guidelines will bediscussed.

Correspondenceto:
TorkelFalkenberg
E-mail: torkel.falkenberg@ki.se150

BOOK OF ABSTRACTS | 12th European Congress of Integrative Medicine · 1st International Symposium on Integrative Health and Education

Title: The attention of Traditional andComplementary Medicine in Mexico

Title: Prevention in Unconventional Medicine

Erika Leyva Mendoza1, Martìn Alberto Rodríguez
Brindis1, Rosa Lilia Garcia Kavanagh1 1Universidad Anàhuac Oaxaca, México

Roberto Fagioli1, Martino Camillo Gianazza1, Marcella Taricco1
1Istituto di Medicina Olistica ed Ecologia Comportamentale “San
Lorenzo in Lodi”

Traditional and complementary medicine has a high percentage ofdemand in developing countries and contributes to the primary health care. The health model combines ancestral wisdom with personalised and comprehensive attention that helps with allopathic medicine.
The object of study was to observe and record the attention andstages of the health model of traditional and complementary medicine in two days of care in the first quarter of 2018 in Mexico. A
descriptive and cross-sectional observational study was carried out,
in two days of care, the sampling was for convenience, including 60
participants who met established criteria. The data collection andanalysis was designed through a case report that integrates generaldata, reason for the demand for care and actions carried out during
the process. Interviews were conducted before and after care, to integrate patient testimony.
Results 60 patients were treated; 62% women and 38% men between the ages of 19 and 66, from Oaxaca 30 and Sonora 30. During
the care in 100% of the patients the practice was observed and recorded in a constant manner of five stages; observation, resonance,
acupressure, percussion fist and assessment, which were performed
regardless of the reason for the care. At the end of the session during
the testimony of the patients, there was a decrease of up to 80% of
the initial symptoms manifested and patients reported “feeling calm,
happy and relaxed.”
Conclusions: The health model of traditional and complementary
medicine is based on traditional knowledge and is complemented byvarious therapeutic practices to establish a relationship of trust patient/therapist, contributing to reduce or eliminate discomfort andensuring their well-being.

Objectives: This work illustrates some of the methods used since
thirty years at our Institute in order to avoid the compensations put
into place by the patient, thus arriving at a clinical picture that is asadherent as possible to his originality.
Material and method:
Study population: male and female adults
Selection criteria: patients with Ren Mai and Du Mai Traditional Chinese Medicine meridians in situation of energydeficit
Sample size: 480subjects
Measurement methods: symptomatological and kinesiological subjectivity
Analysis: Traditional Chinese energetic symptomatology, Kinesiological symptomatology, haematochemical analyses, posturologicalsymptomatology according to Bernard Bricot, serologics, gnathologic semiotics, non-conventional psycho-diagnostics, Hahnemannian
constitutions
Results:
Age distribution and typology of the original traumatic input: 98%
psycho-traumatic etiopathogenesis in pre-school children, 2% in
adults
Allocation of current energy deficit: 79% Ren Mai energetic budget
reduction, 21% Du Mai energetic budget reduction
Discussion: The concept of health and illness in use in the scientificcommunity suffers from being of legal and academic characteristics.
To evaluate the homeodynamics of the patient, in non- conventional
medicine, making use in particular of a holistic methodology, the terms “equilibrium and disequilibrium” are preferred, being more evocative of the clinical status of the patient. Only in the presence of a subject brought temporarily to an equilibrium can we hypothesize on an
effective preventive strategy that takes into account the real impactof the epigenetics on the specific PNEI-P psycho-neuro-endocrine-immune-postural equilibrium of the subject.
Conclusions: All of the Extraordinary Meridians, in particular Du
Mai and Ren Mai, form a preferential route, through which the elements of compensation travel. Their energetic and functional rebalancing allow the examination of the homeodynamics of the subject
in question.

Correspondence to:
Erika Leyva Mendoza
E-mail: garkav@yahoo.com.mx

Correspondence to:Roberto Fagioli
E-mail: nicolovigliani08@gmail.com

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Title: Nordenström & Pischinger, 2 parallel revolutions
Ana Maria Oliva Brañas1
1Profesional libre, Benidorm, AlicanteIntroduction: In recent years we have gone from a physiologicalconcept focused on the cell to a more extended vision through theextracellular matrix and its importance in the regulation, communication and even activation of epigenetic mechanisms. Two great scientists came to the same conclusion from two different routes: Pischinger through the “basic system” and Nordenström through biologicallyclosed electrical circuits (BCEC).
Method and results: The in-depth review of the literature allows us
to observe a significant parallelism in a concept that was called to be
the great revolution in the understanding of pathological processes.
In the 50s, Pischinger began to describe the regulatory role that theextracellular matrix has, developing the concept of a basic system forregulation and nonspecific defence functions. The focus of the basic
unit in pathology then passes from the cell to a functional cell-extracellular-capillary-nerve matrix. It also emphasises the regulatory capacity of the system, and like many of the conventional therapeutic
approaches, instead of improving that regulatory capacity, they inhibit
it, with wholly unwanted effects. At the same time, Nordenström discovered the existence of BCEC, which includes the cell, extracellularmatrix and blood vessels. The correct circulation of electricity in thesecircuits (which we can also correlate with the pH) allows the body torecover the regulatory capacity.
Conclusion: Health is based on optimal communication between
systems and on optimising self- regulation mechanisms. These mechanisms are described through the basic system and the BCEC. We
move from a pathological approach based on a static cause to a functional approach. The great importance of both postulates also lies inthe therapeutic possibilities they offer, confirmed and often forgotten.

Correspondence to:
Ana Maria Oliva Brañas
E-mail: hola@anamariaoliva.es

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Title: Novel Modality in Supportive Adjunct to Pain Management
Srbislav Brasovan1, Sean Martinez2 1Indiana University Medical School 2Tioning Element LLC
Objectives: Develop supportive adjunct in pain management to decrease opioid use.
Material and methods: We utilized 2x2 cm Silicon Patches infusedwith Titanium Salt (SPTS) and imprinted with Extremely Low Electromagnetic Frequency (ELEMF). Being semiconductors, they are passive
ELEMF products. SPTS are activated by a Human Biofield when in contact with the skin. Skin acts as a capacitator. SPTS were researched inphase I double blind study on 15 experimentally injured hairless rats.
Mode of action was analyzed using the computerized Resonant Recognition Model (RRM). The phase II double blind clinical pilot study
has been completed on 20 postoperative abdominal surgery patients
utilizing Won-Baker Pain Rating Scale.
Analysis: RRM analysis found that SPTS remediates pain throughresonances with calcium and sodium pain related ion channels. The
characteristic frequency for pain related sodium ion channel opening
and closing function is fn1=0.1465. RRM frequency relates to electromagnetic wavelength λ=1372nm. Titanium particles in the patches that are in a diameter of about Dλ=1400nm, Dλ/2=700nm andDλ/4=350nm can resonate with pain related sodium ion channels.
Phase II study in ELEMF patch group showed significant reduction in
postsurgical pain intensity.
Results: Phase I research on rats found that SPTS are not harmful
and may enhance wound healing. RRM research has shown that SPTS
could mimic the similar activity as toxin-based pain killers, but without
side effects. Phase II study in ELEMF patch group supports findingsthat SPTS are an excellent adjunct in support of postsurgical pain management.
Discussion: New modality in pain management utilizing nuevo Nano-technology ELEMF passive SPTS has shown to significantly reduceneed for opioid use.
Conclusion: Although results are promising, further studies on large
scale are warranted.

Correspondenceto:
SrbislavBrasovan
E-mail: sbrasova@iu.edu

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Title: Prophylactic Acupuncture
Treatment during Chemotherapy inPatients with Breast Cancer – Resultsof the Qualitative Study Part
Barbara Stöckigt1, Barbara Kirschbaum2, Martin
Carstensen2, Claudia Witt3, Benno Brinkhaus1
1Institute for Social Medicine, Epidemiology and
Health Economics, Charité Universitätsmedizin
Berlin, Germany
2Jerusualem Hospital Hamburg, Germany
3Institute for Complementary and Integrative
Medicine, University Hospital Zurich and University of Zurich, Switzerland
Objectives:
In a randomized controlled trial acupuncture as prophylactic
treatment did not show better quality of life or fewer side effects
of chemotherapy compared to standard care alone in breast cancer(NCT01727362 (clinicaltrials.gov). The aim of the qualitative part ofthis mixed-methods study was to understand better the subjective
perspectives of the patients about quality of life during chemotherapy
and perceived effects ofacupuncture.
Methods:
In a nested retrospective qualitative study semi-structured telephone interviews were conducted with five responders and five non-responders (defined by the primary outcome) who were randomly selected from both studyarms.
Analysis:
The interviews were digitally recorded, pseudonymized, transcribed and then deductively and inductively analyzed according to
Qualitative Content Analysis using the software MAXQDA®. Results
and discussion:
20 patients were included in the qualitative part of the study. In
both groups, most women stated that their quality of life was surprisingly good to what they had expected before starting the chemotherapy. All patients of the acupuncture group experienced theacupuncture treatments as relaxing and beneficial, highlighting theempathic attitude of the therapist. Most of them stated that the acupuncture treatment reduced chemotherapy-induced side effects. For
all patients, finding strategies to cope with the life-threatening cancer
and the side effects of the chemotherapy was primarily essential, e.g.
keeping a positive attitude towards life, selected social contacts andstaying active as much as possible.
Conclusions:
For all patients, coping strategies with the cancer disease seemed
to be more important than reducing side effects. Patients in the acupuncture group reported positive effects on psychological and physical well-being after receiving study intervention.

Correspondence to:Barbara Stöckigt
E-mail: barbara.stoeckigt@charite.de

Title: Integrative health immersion
retreats: a mixed methods observational study with 12- month follow-up
Kathryn Hayward1, Bill Manahan2, Sara Warber3
1InternationalIntegrators
2University ofMinnesota
3University of Michigan
Objectives: Integrative health immersion retreats (IHIR) in natural
settings are increasingly common yet remain little studied. We aim toshare a model of an IHIR and outcomes from an observational study
with 12-months follow-up.
Participants in the 5-day IHIR learn about sustainable self-care,stress reduction, creativity, and relationship-building. They are nourished by plant-based meals, guided movement and mind/body/spirit
disciplines. Key principles include group support, experiential learningand engaging with the natural environment.
Material and method: We examined effects of this IHIR among 30
healthy self-selected participants and staff (ages 28-77, 63% women).
Participants were coping with common life challenges: job change,
burnout, academic stress, divorce, marriage, starting a family, contemplating retirement, grappling with prejudice, emancipating, aging
well. Outcomes included validated scales measuring nature connection and holistic well-being, as well as short written answers.
Analysis: Convergent mixed methods including analysis of quantitative scales change over time (pre-post, pre-3-months) and thematic
analysis of qualitative short answers at 12-months.
Results: Post-retreat, participants experienced less perceived stressand more positive emotions, social support, spiritual transcendence
and connection with nature. Participants endorsed more vibrant senses, feeling empowered, and having the ability to let go and forgive.
Feelings of connection, calmness, joy, wholeness and balance also
improved. At 3-months, participants still experienced improvementin perceived stress, emotional support, feeling more whole and balanced. At 12-months, participants remembered the power of thenatural setting, their experience of community, their self-growth andlearning, the ‘great food’. The retreat changed them personally: ‘balanced’, ‘open’, ‘accepting’, ‘loving’, ‘compassionate’, ‘deeper senseof connection’, ‘hopeful’, ‘joyful’; one person said, I ‘found my heart
again’.
Discussion: Our results suggest that IHIRs have lasting effects on thewell-being of generally healthy individuals.
Conclusions: A 5-day residential IHIR helps people clear the roots ofchronic health challenges that stem from lifestyle choices, relationships, and environment.

Correspondence to:Kathryn HaywardE-mail: khayward@odysseyjourney.com

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Title: Integrating Cupping Therapy(Al-Hijama) in the Treatment of
Tinnitus, Dizziness, Hearing Loss
in Inner Ear Pathologies: A before-and-after Pilot Study
Zainab Almusleh1
1Hamad corporation, Doha-Qatar
Background: Al-Hijama is Arabic term for cupping therapy; it is oneof integrative medicine used by several nations. It’s mechanism of action is not well known but there is several theories explained how it
can play a rule in the treatment of diseases.
In recent years, huge advances have taken place in understandingof inner ear pathophysiology causing sensorineural hearing loss, tinnitus, and vertigo. Research articles providing evidence of acupuncture treating dizziness and vertigo but no studies of Al-Hijama cupping
therapy.
Methods: This is a prospective interventional pilot study in which
pre and post intervention wet cupping therapy (WCT) outcomes wereassessed and compared We studies responds to 6 sessions of post-auricular cupping therapy in 27 patients diagnosed Ménière’s disease(MD) and idiopathic tinnitus or tinnitus secondary to inner ear pathology which tolerated very well without any reported local or systemicside effect. The clinical effect of treating dizziness and tinnitus wasevaluated by performing statistical analyses on data collected fromquestionnaires of Dizziness Handicap Inventory (DHI), Tinnitus Handicap Inventory (THI), Hearing Level (HL) pre and post WCT. Results:
There was significant improvement after 6 sessions of cupping in DHI
and THI (P <0.05) but not in HL. No adverse event was reported in thisstudy
Conclusion: WCT demonstrates a significant effect in reducing discomforts of both dizziness and tinnitus. This study provides clinicalevidence on the efficacy and safety of WCT to be used in the treatment of dizziness and tinnitus. This pilot study may add new modalityof treatment to inner ear pathology like MD, and tinnitus secondary todifferent pathology or idiopathic tinnitus, improve the understandingof possible mechanism of Al-Hijama WCT, despite the lack of otherstudy in this field.

Correspondence to:E-mail: almusleh70@hotmail.com

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Title: The role of context effects in
Acupuncture practice: a qualitative
study based on semi- structured interviews with acupuncturists in threedifferent locations
Sarah Theiss1, Felicity Moir1 1University of Westminster
Introduction: Acupuncture can be considered a complex treatment
intervention, which includes different components leading to an overall treatment effect. Among these, are various factors evoking specific effects and context effects. It has often been argued that context
effects might be especially potent in acupuncture treatments. Since little is known about this aspect of acupuncture treatments, thisstudy aims to explore practitioners’ perceptions of the role of context
effects, and contributing contextual factors, in clinical practice.
Methods: This qualitative study draws on data obtained in semi-structured interviews with acupuncturists in private practice.
To capture the spectrum of acupuncturists’ dealings with context
effects, maximum variation sampling was utilised, and a total of 18
participants from 3 different places were sampled (Seoul, London
and Munich). Thematic data analysis was implemented, combining atheory-driven and a data-driven approach.
Findings: The majority of participating acupuncturists consideredvarious contextual factors, and resulting context effects, to be a fundamental aspect of their treatments. Participants reported they actively implement contextual factors in relation to patients, practitioners, therapeutic relationship, therapeutic ritual, clinical environment
and touch. The overarching aim for implementation, however, was toinduce patient relaxation. Further, acupuncturists highlighted a close
link between contextual and specific treatment factors.
Discussion: Context effects appear to have significant potential inacupuncture practice. Moreover, when considering the aims and methods for their implementation, they seem to be deeply imbeddedin the overarching framework of acupuncture. This becomes evident
through context effects providing the particular supportive structure
to treatments, and through their intimate link to East- Asian medical
theory. In particular, being mainly implemented to enhance patient
relaxation, a state that is considered to powerfully support treatmentsin acupuncture, context effects seem to be inseparable from the specific treatment effects in clinical practice. This proposal might have implications for acupuncture research, practice and education.

Correspondence to:
Sarah Theiss
E-mail: s.theiss@online.de

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Title: Hirudotherapy in minor
replantation or finger revascularization salvage: 5 Years Clinical Results and Experiences of a Level III
City Trauma Hospital
Kaan Gürbüz1 1Kayseri City Hospital
Introduction: Hirudoterapi is an important one of traditional andcomplementary medicine applications which have been used withdifferent indications on a daily basis from ancient times. The mostleading cause of failure or re-anastomosis in replantations is venous
insufficiency.
External bloodletting with medicinal leeches is a common, effective and cost-effective treatment for venous insufficiency after plantations. The objective of this study was to evaluate the clinical results ofminor multiple plantations and/or digit re-vascularizations and present the gained experiences that were treated with medicinal leeches
for venouscongestion.
Methods: Sixty-one patients who were treated with minor multiple
plantations and/or digit re- vascularization at the Kayseri City Hospital
Orthopaedics & Traumatology Clinic between December 2014 andDecember 2019. All patients with venous congestion in one or moredigits replanted or re-vascularized who were treated with medicinal
leeches were included. Treatment initiation and duration were basedon clinical judgement. Demographic, therapy and surgical data werecollected.
Results: Of 61 patients with 94 digits that were replanted and/or
re-vascularized, 78 digits were treated with medicinal leeches forvenous congestion. Venous congestion was diagnosed later than 12hours after operation in 65 of the 78 digits. Of the 78 digits, 52 survived (66,6%) (46 of 52 replanted digits and all 6 re-vascularized digits).
No complications were recorded except for substantial blood loss requiring transfusion in one patient.
Conclusion: Medical leech therapy is an effective treatment modality in hand surgery for minor replantation or finger re-vascularization
salvage, in the treatment of hematomas, post-phlebitis syndrome.
Despite the fact that the reliability of the evidence-based results ofcontrolled, double- blind, prospective patient-based studies is controversial, the advantages and benefits of hirudotherapy in finger replantations isapparent.
Type of study/level of evidence: TherapeuticIV.

Correspondence to:
Kaan Gürbüz
E-mail: drkagangurbuz@gmail.com

Title: The “Taricco Method” for thequantitative study of the verbal reactivity to EMDR stimulation
Marcella Taricco1, Roberto Cesare Fagioli1, Martino Camillo Gianazza1 1Istituto di Medicina Olistica “San Lorenzo in Lodi”
Objectives
Identify and test a new non-invasive methodology that provides
quantitative data to reveal the verbal reactivity of a patient to EMDR.
This methodology was created during research on corpus callosum
functioning.
Material and method
Study population and selection criteria, sample size.
The research was applied to a sample of 20 subjects, patients at
Institute X (name of Institute), with postural and/or occlusal disorders
diagnosed at the Institute, with a control group without occlusal andpostural disorders reset.
Variables and measurement methods.
Examined variables: diagnosis, sex, age, hand and leg dominance.
The method measures the associative stimulus following bilateralocular stimulation and is based on the study of the latency time before reaction and the number of words spoken by the subject.
Analysis
We analysed both the data (latency time and number of words) ofeach subject, and each variable:with longitudinal criteria: variation of reactivity of the same subject
at two different moments.
with transversal criteria: comparison of reactivity in different subjects, to evaluate the role of variables such as sex, ageetc.
Results
With regard to the evaluation of the method, results reveal the following:ease ofapplication
noninvasivenessrapidity and versatility of the data. With regard to clinicalapplication:
improvement in the verbal reaction to EMDR following postural reset, in both longitudinal and transversalanalysis.
Discussion and conclusions
It is concluded that the new methodology provides instant quantitative data to identify the verbal reaction of a patient to EMDR, proves
easy to apply, and is not invasive to the subject.

Correspondence to:Marcella Taricco
E-mail: tariccom@libero.it

BOOK OF ABSTRACTS | 12th European Congress of Integrative Medicine · 1st International Symposium on Integrative Health and Education

Title: Microwave treatment for bone metastases of cancer
Karo Maeda1, Hiroki Takahashi1, Nobuyuki Nagaya1 1Japanese society of Cancer Energy Annihilation Therapy
Bone metastases of cancer are observed in breast cancer, prostatecancer, lung cancer, cancer of unknown primary and others.
Conventional medical treatments for them only consist of medicinal treatments, and their outcomes are not always satisfactory.
The microwave treatment method that we use has been developedand examined in Baylor Medical Collage and other institutions andhas been proven to annihilate cancer activity without adverse effects
or sequelae. Therefore, it has been used to treat 7,000 people in thelast 18 years and has shown excellent outcomes. Here, we report 5
patients who achieved complete cure with this treatment, including 2
patients with severe bone metastases or bone metastasis from cancerof unknown primary.
We jointly acquired a patent for this microwave treatment method
in major countries in the world.

Correspondence to:
Karo Maeda
E-mail: hiro-kwg@pop21.odn.ne.jp

155

Title: Tao Calligraphy Tracing Meditation With Chanting Mantra Improves Quality of Life SF 36 Scores in 6
monthsPeter Hudoba1, Amy Yamashiro1, Cynthia Hamilton1, Jasmine Lau1, Jamie Chow1 1Sha Research
Foundation, San Francisco, California, USA
Objectives:
Although the positive effect of meditation and calligraphy painting
on health is well documented individually, their combined influence
has not been studied (1), (2), (3), (4). The authors have studied theeffect of meditation that combines tracing Tao calligraphy with chanting mantras on the Quality of Live. It was hypothesized that this combination creates a powerful energy field that produces a healing effecton the mind and body.
Method - Design:
In a prospective follow-up, IRB-approved study, the authors investigated the effect of meditating by tracing calligraphy and chanting
mantras on SF-36 scores. Initially, 96 spiritual practitioners were enrolled. After 6 months, 48 remained: 42 women, 6 men, with an averageage of 53 (18-78) years. At the beginning, subjects received instruction
and a transmission and then continued to practice daily meditation of
tracing Tao calligraphy with their fingers while chanting mantras for
10 minutes a day at minimum. The Rand Standardized Quality of Life
Questionnaire SF36 was completed at the start of the study and after
6months.
Analysis - Results:
ANOVA analysis of the survey data showed that all but two measurements exhibited statistically significant positive improvement.
Physical Functioning: change 12.72% P – 0.231;
Role Limitations due to Physical Health Problems: change 19.68%,
P – 0.0134; Role Limitations due to Personal or Emotional Problems:change 28.39%, P – 0.0002;
Energy / Fatigue: change 17.68%, P – 0.0058; Emotional Well-being:change 18.40%, P – 0.0086; Social Functioning: change 17.27%, P –0.0989; Bodily Pain: change 15.34%, P - 0.0501;
General Health: change 13.61%, P - 0.0307. Conclusions:
Results indicate that movement meditation combining Tao calligraphy tracing and mantra chanting improved the quality of life forparticipants as measured by the SF 36 scale. In addition, tracing Tao
calligraphy and mantra chanting was easy to learn, well tolerated andno complications arose.

Correspondence to:Peter Hudoba
E-mail: Sharesearchfoundation @yahoo.ca

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Title: The Power of Touch: External
Applications in the Care of Cancer Patients (Literature Review)
Inga Mühlenpfordt1, Wiebke Stritter1, Mathias
Bertram2, Eran Ben-Arye3, Georg Seifert1 1Charité
Universitätsmedizin Berlin, corporate member ofFreie Universität Berlin, Humboldt- Universität zu
Berlin, and Berlin Institute of Health, Departmentof Pediatrics, Division of Oncology and Hematology
2Doerthe-Krause-Institute for Nursing Scienceand Education, Gemeinschaftskrankenhaus Herdecke gGmbH
3Integrative Oncology Program, Haifa and Western Galilee Oncology Service, Lin and Carmel
Medical Centers, Clalit Health Services, Israel
Abstract
Objectives. External applications are manual treatment modalities
performed by practitioners, nurses and caregivers through the application of touch and warmth to the human skin. They act via biological,
psychological and social processes, in whole medical systems fromcomplementary medicine external applications are connected with aholistic healing intention. The applications can be used in integrative
oncology to improve factors of patients’ wellbeing during illness andimpairments induced by treatments. The purpose of the review is tocollect and compare research results concerning external applications
from different whole medical systems.
Material and Method. We conducted a literature review to explore the effects of external applications on patients undergoing cancer
treatment. Inclusion criteria were external applications applied manually to cancer patients, stemming from Anthroposophic Medicine,
Traditional Chinese Medicine (TCM) and Ayurvedic Medicine andapplied isolated from the treatment spectrum of the originating whole medical system.
Analysis. The research and evaluation process was oriented on the
PRISMA reporting guidelines, integrating sources from databases,
grey literature and expert inputs. Research results in the range of single case and group studies were identified using the specific application terms in combination with cancer/oncology.
Results. Searches identified 111 publications. Final inclusions werefour Shiatsu studies (TCM), supplemented by two case reports exploring Anthroposophic applications. Evidence and reporting was of insufficient quantity and quality. Study results suggest that external applications may potentially improve patients’ wellbeing during cancer
treatment and are associated with physical and psychological effects.
Discussion. In order to depict the effects of external applications
further study designs have to consider the patient-tailored approachand the systemic complexity of touch-based applications based ontreatment modalities from whole medical systems.
Conclusions. The results warrant further high-methodology research. Empirical investigations should assess the effectiveness andunderlying effects of external applications in cancer patients.
Correspondence to:Inga Mühlenpfordt
E-mail: inga.muehlenpfordt@charite.de157

SYMPOSIUM
TARRAGONA

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Introduction Symposium
We are pleased to welcome you to the 1st International Symposium on Integrative Healthand Education. Integrative Health is a new model of health care that emerged at the beginningof the last decade in response to consumer demands for more holistic health care. It reflects
society’s needs and expectations in relation to a cultural evolution and a different sensitivity
towards health care. This health model focuses on the person, and its main objective is the wellbeing of the person as a whole beyond the suppression of the symptoms. A health problem istreated from an integral perspective that encompasses the whole person and considers healthas an emergent property of the person in a given environmental context.
This symposium aims to be a forum for exchanging knowledge and experiences among
members of the education community from different countries to learn the state-of-the-art ofthe educational framework of integrative health. The main objective is to facilitate a dialogue
about practice, research and education, to help us determine guidelines for regulating an integrative educational framework.
The symposium starts with a round table which presents the international education experiences of countries such as the United States, Europe and Iceland. Some Spanish teachingexperiences are presented in a second-round table. Then attendees are invited to participate,reflect on the presentations and evaluate the contributions and proposals in this field.
We are excited to share this meeting with you and hope that it is the start of a dialogue thatwill help us determine a line for integrative health education.

Roser Ricomà Muntane
Neus Esmel Esmel
Congress chairs
Tarragona, 12 september 2019

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Health and Healing Academic Programs
Earl E. Bakken Center for Spirituality & Healing Integrative
Since 1995, the Earl E. Bakken Center for Spirituality & Healing at
the University of Minnesota has been conducting research, educating
health professionals and advancing innovative care delivery models
that focus on integrative health and medicine. Our faculty, nearly 80
in number, come from diverse academic backgrounds. Approximately 2,000 students take academic graduate or undergraduate levelcourses each academic year through the Center and many thousands
participate annually in our community‐based programs, workshops
and on‐ line learning opportunities. Our website Taking Charge ofYour Health and Wellbeing (https://www.takingcharge.csh.umn.
edu/) attracts close to 250,000 unique visitors per month from aroundtheworld.
The Bakken Center offers many interdisciplinary learning opportunities including a master’sdegree in integrative health and wellbeing
coaching, a graduate certificateand a graduateminorin integrative
therapies and healing practices. Many health professionals enroll inthese degree programs or take coursesas a non‐degree student for
personal growth and professional development. Recently, a specialization in integrative health and medicine was created that is offeredthrough Coursera.
We also collaborate with other University of Minnesota collegesand departments to offer the following learning opportunities:
Doctor of Nursing Practice in Integrative Health andHealing
Bachelor of Individualized Studies: Concentration in Human HealthandWellness
Inter‐College Bachelor’s Degree Program: Concentrations in Whole
Systems Healing or Holistic Health and Healing; thematic degree in
Health andWellness
Health Care Design and Innovation Post‐BaccalaureateCertificate
During the roundtable conversation in Tarragona, Dr. Mary Jo Kreitzer will highlight three of these academic programs: the Doctorateof Nursing Practice in Integrative Health and Healing, the Masters degree in Integrative Health and Wellbeing Coaching and the opportunities that students have to self‐design their own learning programs
through the graduate certificate and minor in integrative therapies
and healing practices.

Training in complementary and integrative medicine in Italy and experience intraining for health professionals in Tuscany.
Elio Rossi*, Susanna Fambrini*** Homeopathic Clinic of the Hospital Campo diMarte, Lucca (Italy) – Regional center of reference
for homeopathy. Coordination center for Complementary Medicine of ASL Tuscany North West** Serristori General Hospital, Florence, Local
Health Unit Tuscany Centre
Introduction:Internationalliteratureinthisfieldreportedeviden-ceonsafetyandefficacyinreducing some side effects of anticancer-therapy (nausea, vomiting, anxiety, pain, and slight depression and sleep
disturbances). The Local Health Unit Tuscany Centre introduced sinceApril 26, 2017 at Serristori General Hospital in Figline and Incisa Valdarno, traditional Chinese medicine first level treatments exclusively
in the care of cancerpatients.
Aim:ThegeneralobjectiveofthisprojectistointegratetraditionalChinesemedicinetreatmentswith the usual care treatments in cancer
patients’ clinicalpathways.
Materials: This project accounts four nurses trained in auriculartherapeutic treatments, acupressure and plum blossom needle according to specific agreed protocols. Patients who suffer frominsomnia,
pain and anti-emetic drug use receive these treatments after a complete information about this therapeutic approach. A psycho-oncologist first evaluates the degree of anxiety and depression. Symptoms
trends are evaluated using specificquestionnaires.
Results: 35 patients were treated until December 31, 2017. The
major pathologies treated were lung cancer: 9 patients (25.71%) andlymphoma: 6 patients (17.14%). Total treatments were 361. Seven patients abandoned the study (3 due to death, 3 due to failed compliance, 1 due to excessive pain when treated). Fourteen patients completed the treatment; the questionnaires of six of them were evaluated(3 for anxiety and 3 for insomnia).
As far as anxiety is concerned, there was an improvement in discomfort in the absolute value of 5.50
<28.21% of the initial discomfort value (started after the second session). For insomnia there was an improvement in discomfort (started after the fourth session) of 14 points (<51.85% of initial discomfort value).
Conclusions: The model described in this project allows widening
the therapeutic approaches in oncology, offering to the numerous
cancer patients, who frequently require complementary treatments(Eurispes 2017), appropriate and safe care opportunities, within andin synergy toofficial healthcare services, with improvement of symptoms and quality oflife.

References
1. Elisabetta Barbara Cortesi, Sonia Baccetti, Maria Valeria Monechi, Mariella Di Stefano, Barbara Cucca, Tommaso Conti, Antonella Traversi, Filippa
Terranova, Roberto Montelatici, Sylvie Yvonne Barberousse, Federica Sabatini, Catia Vuono, Christian Bini, Marco Picchi. Observational Study on Auriculotherapy in the Treatment of Chronic Musculoskeletal Pain: Preliminary
Data OBM Integrative and Complementary Medicine2019, volume 4, issue
2 doi:10.21926/obm.icm.1902028

Complementary Therapies: Nursing education in Iceland
Gunnardosttir, TJ, Phd, Faculty of Nursing, Reykjavik (IS)The use of complementary therapies in Iceland among the public isrising. Within the health care system needs to be increased discussion
about how integrative health care can be strengthenandfurthereducationonthismatterisneededtoinformallhealthcarestudentsabout theuse of complementary therapies and integrative health for the benefitof patients. The FacultyofNursingattheUniversityofIcelandhasbeentakingpartinresearchingandeducating aboutcomplementarytherapie-

BOOK OF ABSTRACTS | 12th European Congress of Integrative Medicine · 1st International Symposium on Integrative Health and Education

sandintegrativehealthpractices.Thishasbeendonebyoffering lecturesand seminars at the National Hospital, collecting data on the use within the National Hospital, among the public and in nursing homes.
The Faculty of Nursing has renewed its curriculum and as part of thatis now offering six credit course for all nursing students about publichealth and self-mental care, complementary and integrative health.
The course lectures andworkshopsaboutcomplementarytherapiesand patient’ssymptomsandsafeuse.Thismay alsobebeneficialforstudentstodealwithstressandincreaseself-carewhichmaybeofspecial importance now since recent studies are showing that nursing students
are reporting increased stress and burnout during theirstudies.

Integrative Medicine inAustralia
Presenter: Professor Avni Sali(Australia)
There are two main types of medicine in western countries: Prescription Medicine which dominates and Integrative Medicine (IM) which is
growing to be the medicine of the future.
In general there has been lack of government support for Integrative
Medicine, both for consultations and research. This has made it difficult
to progress Integrative Medicine.
In the USA the momentum of Integrative Medicine has moved at amore progressive pace. In 2014 the American Board of Physician Specialties formally recognised ‘Integrative Medicine’ as a medical specialty, likeany other speciality eg. Surgery or Psychiatry. Almost all medical schools
in the USA provide some form of integrative medicine education.
In Australia none of the university medical schools provide integrative
medical education.
The National Institute of Integrative Medicine (NIIM), located in Melbourne and in another state, is the leading clinical medical Education andResearch Centre in Integrative Medicine in Australia.
The major representative bodies in integrative medicine in Australia
are -The Australasian Integrative Medicine Association (AIMA) and The
Australasian College of Nutritional and Environmental Medicine (ACNEM). AIMA was set-up to represent Doctors who practice Integrative
Medicine and ACNEM is primarily focused on education and representation.
Naturopathy centres traditionally have been involved predominantlywith education, but are now also beginning to do some research.
At NIIM, our vision is to create a medical model for all to experience
optimal health and wellbeing through Integrative Medicine. We envisage that one day all medicine will be ‘Integrative Medicine’.

How to learn integrative health?
Tinao, JF, Director of the CMI clinic and the observatory of integrative medicine (Madrid/SP)“Health training programs are directed under the philosophy of positivism that appears at the end of the 19th century.
We have all been trained in this model. The entry of the modelthat represents Integrative medicine forces a profound transformation in universities and health schools.

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We are in a phase of change and crisis. We are looking
for a new teaching model that responds toanewprofessionalwhoisabletooffersolutionstothenewapproachesofcurrenthealthand disease”

Integrative Medicine in Spain: Regulation process
Rigau, J, MD, Master in pharmacogenetics andpharmacogenomics and environmental medicine (Tarragona/ SP)In recent years from government institutions there has
been an irrational and ruthless persecution against what theycall “unconventional medicines”
Suppressing university courses of great tradition and success.
Preventing training courses and / or congresses alleging
that they had no scientific basis. Criminalizing doctors andpatients for their action or evenopinion.
Therefore, in 2018 the State Board for the Regulation of
Traditional, Complementary and IntegrativeTherapies(MTC)
wasestablished.Todemandadequateregulationforsuchdisciplines and therapies, WHO recommended the Strategic Plan
2014-2023 on Traditional and ComplementaryMedicines.
Therefore, the debate for regulation is an open one.

“Máster de Acupuntura, Etiqueta de Excelencia de la Universidad de Barcelona,
16 años de docencia”.
PONENTE: Dra.CristinaDomingoGómez,MedicaAcupuntora,DirectoradelMásterdeValoraciónde la Energética y Acupuntura de la Universidad
de Barcelona, y del Máster de Medicina Tradicional China y Acupuntura del Campus Docent
Sant Joan deDéu.
RESUMEN:
La formación en Medicina Integrativa en el Campus Docent SJD,
adscrito a la UB es muy amplia, con tres Masters en Medicinas Complementarias (Acupuntura, Terapia Neural y Ayurveda), de 60 créditos
ECTS cada uno, y la integración en el Graduado de Enfermeria y en elde Técnico Curas Auxiliares de Enfermeria (TCAI) con asignaturas especificas optativas en Terapias Naturales y Nutrición complementaria,
y de manera implícita en once asignaturas troncales.
El Máster en Valoración Energética y Acupuntura recibió en año
2018, el reconocimiento de la UB con la Etiqueta de Excelencia y de la
Academia de Ciencias Médicas y de la Salut de Catalunya y Baleares

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con el Aval de la Sociedad Científica de Acupuntura.
La investigación es un pilar fundamental en el Campus Docent SJD
y en nuestro Máster, habiendo dirigido 336 Tesinas de fin de Máster
y otorgando a las más destacadas cada año el premio Acupuntury en
investigación Clínica, que este año cumplirá la 17ª edición.
Nuestroesfuerzoeninvestigaciónincluyeestudiosaleatorizadosqueformanpartede cinco tesis Doctorales en curso, destacando la realizada en el HSJD “Eficacia de la Acupuntura y Moxibustión en el tratamiento de la presentación denalgas”.
La Formación Continuada de nuestros profesionales Acupuntores,
es constante, con seminariosdesupervisióndecasosclínicos,deformaciónenacupunturaavanzaday ampliación de conocimientos en los
Hospitales deChina.

Experiencias educativas en salud integrativa desde el ambito nacional
Recorrido de las t.C en el grado de enfermeria de la fcsbde la uvic
Anna Rovira Sadurní
DUE, Profesora de la Facultad Ciencias de la Salud y el Bienestar. Universidad de Vic- Universidad
Central de Catalunya
La comunicación presenta una reflexión sobre el recorrido histórico
de las Terapias complementarias (en adelante TC) en la Facultad deCiencias de la Salud de la Universidad de Vic, con el objetivo de plantear nuevos retos en su incorporación permanente en el Grado de enfermería. El trayecto a lo largo de los años ha sido irregular e inmerso
periódicamente a cambios.
Desde los años 90 las TC están presentes en los estudios de enfermería de la UVIC pero no con la misma intensidad, implementación yforma. Distintos elementos han influenciado en su aplicación. El propio proceso histórico de cambio institucional, de Estudios Universitarios a Universidad, las modificaciones de planes de estudio, opiniones
o tendencias a mantener un paradigma biomédico y cierto rechazohacia la falta de evidencia, han propiciado la variabilidad en su aplicación. A pesar de todo las TC han estado de una forma u otra siempre
presentes en el Grado, pero no de manera explícita.
La metodología y la forma de implantación de las TC han sido diversas. En sus inicios se realizaron talleres en la asignatura de Fundamentos de enfermería, en la formación de pregrado. Posteriormente con
el nuevo plan de estudios aparece la posibilidad de impartir, además,
una asignatura optativa sobre T.C. En este período se inicia también laformación en Posgrado, se crea un Posgrado sobre
T.C. y distintos cursos de formación continuada para profundizar en
terapias concretas (reflexoterapia podal, aromaterapia, entre otras).
Después de este periodo, y por distintos motivos coyunturales a lasituación de la Facultad de Ciencias de la Salud y el Bienestar se deja
de ofrecer la asignatura optativa, pero se mantiene y se desarrolla uneje sobre estrategias mentales, a lo largo de los 4 cursos de Grado.
Así mismo, se introducen conceptos básicos sobre TC en distintas asignaturas, entre ellas los Prácticums y Estrategias de intervención en eldolor crónico. Actualmente desde el curso 2018-19 se vuelve a ofrecerla asignatura optativa de T.C y enfermería, desarrollando los módulos
de Fitoterapia y Reflexología Podal. Los resultados muestran un alto
grado de satisfacción de los alumnos en relación con este último curso y en el análisis aparece reiteradamente palabras como descubrir e

integrar.
A pesar de que, a lo largo de estos años, las TC se han mantenido
en el currículum de enfermería, cabe plantearse si la forma, fragmentada y optativa en que se han venido implementando, contribuye aldesarrollo de la enfermería y responde a las necesidades reales de losusuarios.
¿Puede la Universidad obviar la responsabilidad de no formar profesionales que integren las distintas TC y dejar de trabajar hacia unmodelo integral? Fernandez- Cervilla (2013) orienta una respuesta indicando que la ausencia de formación en las universidades españolas
conlleva que el tratamiento y asesoramiento al paciente este mermado y no se disponga de profesionales competentes en esta materia. La
universidad es el primer eslabón de formación de los futuros profesionales enfermeros, es imprescindible liderar estrategias para conseguir
la integración de las TC en asignaturas troncales. En consecuencia, es
necesario sumar esfuerzos frente a los distintos impedimentos sociales, institucionales, políticos y económicos que dificultan su implementación. Además, como indican Gonzalez y Quindos (2010) “lasdiferentes corrientes de pensamiento de la disciplina enfermera nos
describen escuelas con modelos conceptuales en los cuales las terapias naturales pueden integrarse, ya que tiene en común una visiónde los cuidados en valores humanistas”.
A pesar de las reticencias fundamentadas en una supuesta falta deevidencia científica, hay razones suficientes para integrar las TC en el
grado de enfermería. La aceptación y uso de las TC por gran parte de lasociedad actual y de profesionales de la salud, la eficacia demostrada
en determinados problemas de salud, las recomendaciones de las instituciones europeas, la OMS, y el incipiente inicio de experiencias deintegración son algunos de los argumentos que pueden sustentar la integración de las TC, de forma definitiva y no cuestionable en el currículum. Su presencia permanente en éste permitiría desarrollar y afianzar
un modelo de atención integral, evitando que las TC se continuaran
viendo inmersas en un contexto de vulnerabilidad permanente.
Bibliografía
Fernández-Cervilla, AB; Piris-Dorado, AI; Cabrer-Vives, ME; BarqueroGonzález, A. (2013). Situación actual de las T.C en España en el Grado de Enfermería. Rev.Latino-Am. Enfermagem. Mayo-junio. Consultado 25/06/19
en: http://www.scielo.br/pdf/rlae/v21n3/es_0104‐1169‐rlae‐21‐03‐0679.
pdf
Gonzalez, E; Quindós, A. (2010). La Incorporación de Terapias Naturales
en los servicios de Salud. (Tesis doctoral, Escuela Universitaria de enfermería Santa Madrona, 2010). Consultado 26/06/19 en : http://diposit.ub.edu/
dspace/bitstream/2445/21702/1/2009_8.pdf
Gonzalez, E; Quindós, A. (2010). La Incorporación de Terapias Naturales
en los servicios de Salud. (Tesis doctoral, Escuela Universitaria de enfermería Santa Madrona, 2010). Consultado 26/06/19 en : http://diposit.ub.edu/
dspace/bitstream/2445/21702/1/2009_8.pdf

Educational experiences of integrative
health in Zaragoza (Aragón), past, presentand future.
Fernández Fortún, Tomás.
Nurse, postgraduate in natural medicine, Directorof the natural nursing department of the official
nursing college of Zaragoza.

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Keywords:
Natural Medicine, Natural Nursing, Integrative Health.
Zaragoza is a city of 650.000 people located in the northeast of
Spain. It is the capital of the region of Aragón. It concentrates the coreof the educational offer within the region.
Integrative health educational experiences in Zaragoza has developed through three paths: University of Zaragoza, official nurse school,
and others.
University:
Since the incorporation of undergraduate nursing studies as a university degree in 1977, the basics of integrative Health are included
in its program (such as nutrition, exercise, relaxation techniques,
psycotheraphy, breathing, circadian rhythms, environmental health,etc.). In a more specific way other nursing conceptual models are also
included: Florence Nightingale, Martha Rogers, Virginia Henderson,
Margaret Newman,…
In a special way in the public studies of the University of Zaragoza,
the faculty of health sciences in three occasions has contemplated
subjects of free departmental configuration denominated: Fitoterapy, Homeopathic. However, the class that remained offered more
often was Natural Medicine (from 2000 to 2005). Its program offersa theoretical and practical basis of: legal framework, medical plants,
nutrition, yoga, relaxation techniques, energetic techniques, and Hydrotherapy, geobiology and healthhouse.
Postgraduate studies in Natural Medicine at Medical School (Nursing School depends of the Medical School) have been one of thestudies with most relevance in the last 20 years (since 1992). The
Homeopathic Master and the Master in Health Sciences in particular.
From different degrees, it has also been offered postgraduate studies in Acupuncture and Moxibustion (Foundation Business-University), Musictherapy (Teaching Degree).
Currently a Master in Mindfulness by the University of Zaragoza is
the key offer. Summer courses from the University of Zaragoza are theoldest in Spain (since1927)
In Jaca (Huesca) the University of Zaragoza has organized during
different years courses on topics such as Clinical, Educational andSocial Music Therapy, Molecular Biology, Humor and Philosophy, Natural Birth and others; and in its Campus of Teruel has been offeredconsecutively in botany and medicinal plants of the Iberian system(30th edition), Natural Environment as an educational resource, Comprehensive Approach of the Oncological Sick, Music Therapy, Mindfulness ... Also that in the public offer there have been postgraduate
studies, although more concrete, as in environmental health or on
Aromatherapy and Essential Oils.
From the San Jorge Private University of Zaragoza, the elective course for 4th grade students, called Alternative and Complementary Therapies of 75 teaching hours, is held in undergraduate studies.
Also in the offer from the public university, there has been the possibility of taking postgraduate studies in environmental health or on
Aromatherapy and Essential Oils,
From the Nursing Specialties through the RIN program (ResidentInternal Nurse) in the training years, are specifically included, from theMultidisciplinary Teaching Unit, studies on Integrative Nursing in theSpecialties of Community Nursing, Pediatric Nursing, Obstetrics-Gynecology Nursing and in Mental Health Nursing
Professional Chamber:
The Professional Chamber of Nursing of Zaragoza, in 1994, founded
what would be the first Collegiate Section or Department of Naturist

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Nursing in a Nursing Professional Chamber in Spain. Currently, there
are more than one thousand Zaragoza nurses enrolled.
Since then it has made countless training offers in Integrative Nursing (conferences, workshops, courses, seminars, ...) without forgetting the research aspect (publications, advice and professional practice).
In 1995, the 1st course in Naturist and Integrative Nursing and theFirst Days on Integrative Nursing were held with great success of assistance. This could take place after an intense first year of workshops
and shorter workshops.
It should also be noted that in 1997, allegations were made to thethen novel Project for the Regulation of Therapies in Europe Paul Lannoye, which initially left out nursing, ending a reversed situation.
It has a large library with numerous volumes and professional andinformative magazines on the subject.
The SEN (Section of Naturist Nursing) within the framework of its
biannual Days of Naturist Nursing, in its 10th edition, has celebrated
its 25th anniversary.
The Chamber, through this department, keeps Monday and Wednesday (mornings and afternoon) a space for Yoga and Relaxation Techniques. These sessions are open to nurses and to the general public.
Currently training courses are also being offered. At this point, thousands of activities and tens of thousands of teaching hours have takenplace.
Other:In 2013, the Professional Chamber of Nursing of Zaragoza signed a
training alliance in Integrative Nursing with ASENZAR, (Association of
Naturist Nursing of Zaragoza) and in 2019 with ACEIZ, (Scientific Association of Integrative Nursing of Zaragoza - www.aceiz.es)
For example, only ASENZAR, in 2017, offered or promoted as integrative educational activities for free: 44 Conferences, 20 Courses, 40
Workshops, 12 Teaching Classrooms in Holistic Kinesiology, 11 Workshops Collaborative Economy, Several book presentations, 8 days of environmental health with tastings and gifts from ecological oil makers,... and has recommended 34 fairs, congresses and conferences.
And equally but with cost: 11 Courses, 5 Congresses, 4 Days ofOpen Doors, ... and has participated in several programs of the regional TV: “Medicinal Uses of the Onion” and “Natural Remedies for theSummer”.
The “Alternative Holidays in August” are a success each year and include numerous workshops and educational formations varied: Chromotherapy, Neural Therapy, Nonviolent Communication, Meditation
Techniques, Aromatherapy, Natural Food, ...
Regarding Labor Unions: The CNT Union has held several conferences on Natural Medicine, CCOO and UGT through the sector tables
for 9 years got-through BOA- (Official Gazette of Aragon), Official Training and Baremable from Health (Public Health System de Aragón) for
public health personnel in: Geobiology and Casa Sana, Introduction
to Natural Medicine for Groups A and B health, Yoga and Relaxation
Techniques, Phytotherapy, Medicine of Humor and Laughter ...
The last event was the National Congress of Nursing held in Zaragoza and organized by CSIF with Presentations on Meditation, or Integrative Health. Resulting winners of the scientific prize in poster format
in 2nd and 3rd place the works: “Nursing Interventions at Risk of Exclusion in Spain by Royal Decree” and “Need for an Emotional Health
Consultation in Primary Health Care”. The SATSE Syndicate has also
conducted courses to use on various integrativesubjects.
On the other hand, it should be mentioned, that there is also in ourcity a varied offer from private entities such as schools of Naturopathy,

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Acupuncture, Osteopathy, Reflexology, and a long etcetera
Future:We still have to solve the problem of Regional concessions of National CFC teaching accreditations, to have specific training in Undergraduate Public University Studies or to have a weight in the different
subjects as it would be desirable, to achieve a greater offer in Official
University Masters and Postgraduate Degrees and own studies, topromote integrative educational offers from the same public HEALTH
system and continue to encourage Integrative Health as an Essential
Good in public and private health for the patient, the person and thecommunity in its broadest sense.

Shinrin-yoku: Environments for PurposefulIntegrative Healing
Margaret Mary Hansen Ed.D., MSN, RN
Professor of Nursing
Purpose: The aim of this presentation is to illustrate an in-depth review of the literature regarding the Japanese practice of Shinrin-yoku(forest bathing) and its associated healing benefits for the humanmind, body and spirit. Watson’s Theory of Human Caring and Caritas
ProcessesTM (2008): “Create a healing environment for the physical and spiritual self which respects human dignity” and “Use creative
scientific problem solving methods for caring decision making” act asa framework forShinrin-yoku.
Background: Current research indicates an increase in human stresslevels may be attributed to living and working in urbanized environments worldwide. Over the past six to seven million years we have
evolved into what we are today as a human species and 99.9% of thattime has been spent living in natural environments (Song et al., 2015).
A multitude of current empirical studies support the existing awareness of the important link between natural environments, trees,
plants and forests have on well-being and purposeful healing (Song,Ikei, & Miyazaki, 2015; Lee, Lee, Park, & Miyazaki, 2015; James et al.,2015; Kuo, 2015; Song, Ikei, & Miyazaki, 2016; Hart, 2016).
Design: A comprehensive search of the literature related to forest
bathing and nature therapy was completed to review findings published during the last seven years.
Data Sources: Electronic databases: PubMed, CINAHL, PsychINFO,
and Scopus were used for the integrative approach.
Review methods: Keyword searches were conducted for studies
published 1998-2016 that looked at the effects of Shinrin-yoku, and/or forest bathing, and/or nature therapy on human psychologicaland/or physiological well-being.
Results: From 93 published studies that were initially scanned forcontent applicability, 69 studies were included in the detailed review.
Conclusion: Shinrin-yoku, as a healing modality for the physical,
cognitive and spiritual self is supported by the research conducted intrans-continental Japan and China. However, there is a dearth of empirical research regarding the benefits for individuals residing in North
America. Watson’s Theory of Human Caring and current literature supports further research endeavors.
Bibliography
Hart, J. (2016). Prescribing nature therapy for improved mental health.

Alternative & Complementary Therapies, 22(4), 161-163. doi:10.1089/
act.2016.29067.jha
James, P., Banay, R. F., Hart, J. E., & Laden, F. (2015). A review of thehealth benefits of greenness. Current Epidemiology Reports, 2(2), 131-142.
doi:10.1007/s40471-015-0043-7
Kuo, M. (2015). How might contact with nature promote human health?
promising mechanisms and a possible central pathway. Frontiers in Psychology, 6 doi:10.3389/fpsyg.2015.01093
Lee, M. S., Lee, J., Park, B. J., & Miyazaki, Y. (2015). Interaction with indoor
plants may reduce psychological and physiological stress by suppressing autonomic nervous system activity in young adults: A randomized crossoverstudy. Journal of Physiological Anthropology, 34(1) doi:10.1186/s40101015-0060-8
Song, C., Ikei, H., Kobayashi, M., Miura, T., Taue, M., Kagawa, T., Li, Q….
(2015). Effect of forest walking on autonomic nervous system activity in middle-aged hypertensive individuals: A pilot study. International Journal ofEnvironmental Research and Public Health, 12(3), 2687-2699. doi:10.3390/
ijerph120302687
Song, C., Ikei, H., & Miyazaki, Y. (2015). Elucidation of a physiologicaladjustment effect in a forest environment: A pilot study. International
Journal of Environmental Research and Public Health, 12(4), 4247-4255.
doi:10.3390/ijerph120404247
Song, C., Ikei, H., & Miyazaki, Y. (2016). Physiological effects of naturetherapy: A review of the research in japan. International Journal of Environmental Research and Public Health, 13(8) doi:10.3390/ijerph13080781
Watson, J. (2008). Nursing: The philosophy and science of caring (Rev.
ed.). Boulder, CO: University Press of Colorado.

Workshop

The GIM-Method (Guided Imagery andMusic): How to mobilize inner resources ofhealth through music-listening.
Mahilan, C Ayllón, L
Musictherapy actually is a very important treatment in clinical work
especially in psychiatry, psy-chosomatic medicine, neurology, oncology, pediatrics, neonatology, surgery, palliative care…
The proved benefits based on evidental studies are: improvementof anim status, reduction of anxiety, relaxation and decrease of secundary effects like pain and problems of breathing (in case of oncological deseases), improvement of self-perception, stimulation of self
healing, activation of inner resources of health, improvement of life
quality, etc…
This workshop (practical and theorical) has as purpose the experience of the receptive musicther-apy method of Guided Imagery andMusic (GIM). GIM is a work tool for personal growth and fa-cilitates
self-knowledge, inner resources and creativity for better quality ofdaily life.
We offer you a space for personal exploration in group through music listening in state of deep re-laxation.

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