Ⅲ-3. Radiochemistry & Nuclear Chemistry

RIKEN Accel. Prog. Rep. 49 (2016)

Production cross
cross sections
sections ofd,x) reactions
Productionof ((d,x)
reactionson
onnaturalnaturalplatinum
platinum† †M. U. Khandaker䠆1,䠆2 and H. Haba䠆2
An accurate knowledge of nuclear reaction phenomena oflight charged particles with platinum shows significancedue to its various applications in science and technology.
The microscopic experimental cross-sections of platinum
are very useful for the production of medical radioisotopes,
the verification of nuclear reaction theory, the thin layeractivation analysis, etc. Recently, we investigateddeuteron-induced reaction cross sections from various target
elements because measured data of the (d,x) processes arelimited compared to those of (p,x) processes. A survey ofliterature shows that several investigations have been
conducted for the natPt(d,x) reactions leading to variousapplications. As an example, the production of the 198gAu
via the natPt(d,x) reaction finds applications in targetedradiotheraphy and imaging procedures 1,2). Its half-life issuitable for an uptake and residence time of antibodiesespecially in the treatment of solid tumors without asignificant loss of activity. Due to the monoisotopic
characteristic of 197Au target, the 197Au(n,J)198Au reaction
with a nuclear reactor of quite moderate power is currently
being utilized as a commercial production route for 198Au in
many countries for clinical use 2). But the successive andsimultaneous formation of 199Au via the secondary
198
Au(n,J)199Au reaction is significant because of its very
high cross-section, and therefore causes a small portion of199
Au isotopic impurity and reduce the specific activity of198
Au. Thus, measurements of new experimental
cross-sections via the deuteron irradiation on natural
platinum are expected to provide new production pathways
for the no-carrier-added 198Au.
The objective of the present study was to report the latest
natPt(d,x)
crosssectionsof
the
192,193,194,195,196m2,196,198m,198,199
195m,197
Au,Pt
and190(g+m1+0.086m2),192(g+m1),194m
Ir reactions that were measured
with a high precision over the energy range of 2–24 MeV
using the AVF cyclotron facility of the RIKEN RI BeamFactory, Wako, Japan. Details on the irradiation technique,radioactivity determination, and data evaluation procedures
are available in Ref. 3). Owing to the space limitation of thisreport, we present only the natPt(d,x)198gAu cross sections
and the deduced yield in Figs. 1 and 2, respectively.
Measured cross sections with an overall uncertainty arelisted in Ref. 3). The cross-sections were normalized byusing the natTi(d,x)48V monitor cross sections recommended
by IAEA. Measured data were critically compared with theavailable literature data and theoretical data, and only
partial agreements were obtained with the earlier
experimental and theoretical data extracted from theTENDL-2013.

The deduced thick-target yields indicate that a low amountof no-carrier-added 198gAu could be obtained on an enriched198
Pt (100%) target with the yield of 22 MBq/μA-h at 15
MeV deuteron energy from a cyclotron.

Fig. 1. Excitation function of the natPt(d,x)198gAu reaction.

Fig. 2. Physical thick target yields for the 199,198g+m,196,196m2Au and195m
Pt radionuclides.
References1) J. Horiuchi, M. Takeda, H. Shibuya, S. Matsumoto, M.
Hoshina, S. Suzuki: Radiotherapy and Oncology 21, 29(1991).
2) D. E. Berning, K. V. Katti et al.: Nucl. Med. & Bio. 25, 577(1998).
3) M. U. Khandaker, H. Haba et al.: Nucl. Instrum. Meth. Phys.
Res. B 362, 151 (2015).

†Condensed from the article in Nucl. Inst. Meths. B. 362, 151 (2015).
Department of Physics, University of Malaya
䠆2RIKEN Nishina Center䠆1- 244 -