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Material Safety Data Sheetacc. to ISO 11014
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Reviewed on 05/29/2015

1 Identification· Product identifier· Trade name: Bioware Brite Cell Line MCF7-Red-FLuc· Product number: BW119262v· Relevant identified uses of the substance or mixture and uses advised against
No further relevant information available.
· Application of the substance / the mixture Laboratory chemicals· Details of the supplier of the safety data sheet· Manufacturer/Supplier:
PerkinElmer Inc
549 Albany stBoston, MA 02118· Information department:
US Technical Support800-762-4000· Emergency telephone number:
If inside USA, call CHEMTREC at 1-800-424-9300
If outside USA, call CHEMTREC at 1-703-527-3887

2 Hazard(s) identification· Classification of the substance or mixture
The product is not classified according to the Globally Harmonized System (GHS).
· Label elements· GHS label elements Void
· Hazard pictograms Void
· Signal word Void
· Hazard statements Void
· Classification system:· NFPA ratings (scale 0 - 4)010

Health = 0
Fire = 1
Reactivity = 0

3 Composition/information on ingredients· Chemical characterization: Mixtures· Description: Mixture of the substances listed below with nonhazardous additions.
· Dangerous components:
67-68-5 dimethyl sulfoxide

2.5-10%· Additional Components
990001-01-2 Fetal Bovine Serum

75-100%4 First-aid measures· Description of first aid measures· General information: No special measures required.
· After inhalation: Supply fresh air; consult doctor in case of complaints.
(Contd. on page 2)
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Trade name: Bioware Brite Cell Line MCF7-Red-FLuc(Contd. of page 1)· After skin contact: If skin irritation continues, consult a doctor.
· After eye contact: Rinse opened eye for several minutes under running water.
· After swallowing: If symptoms persist consult doctor.
· Most important symptoms and effects, both acute and delayed No further relevant information available.
· Indication of any immediate medical attention and special treatment needed
Follow the advice given in section 4.1

5 Fire-fighting measures· Extinguishing media· Suitable extinguishing agents:
CO2, extinguishing powder or water spray. Fight larger fires with water spray or alcohol resistant foam.
· Special hazards arising from the substance or mixture No further relevant information available.
· Advice for firefighters· Protective equipment: Wear self-contained respiratory protective device.

6 Accidental release measures· Personal precautions, protective equipment and emergency procedures Not required.
· Environmental precautions:
Dilute with plenty of water.
Do not allow to enter sewers/ surface or ground water.
· Methods and material for containment and cleaning up:
Absorb with liquid-binding material (sand, diatomite, acid binders, universal binders, sawdust).
· Reference to other sections
See Section 7 for information on safe handling.
See Section 8 for information on personal protection equipment.
See Section 13 for disposal information.

7 Handling and storage· Precautions for safe handling No special measures required.
· Information about protection against explosions and fires: No special measures required.
· Conditions for safe storage, including any incompatibilities· Storage:· Requirements to be met by storerooms and containers: No special requirements.
· Information about storage in one common storage facility: Not required.
· Further information about storage conditions: None.
· Specific end use(s) No further relevant information available.

8 Exposure controls/personal protection· Additional information about design of technical systems: No further data; see item 7.
· Control parameters· Components with limit values that require monitoring at the workplace:
67-68-5 dimethyl sulfoxide (2.5-10%)
WEEL Long-term value: 250 ppm(Contd. on page 3)
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Reviewed on 05/29/2015Trade name: Bioware Brite Cell Line MCF7-Red-FLuc(Contd. of page 2)· Exposure controls· Personal protective equipment:· General protective and hygienic measures:
The usual precautionary measures for handling chemicals should be followed.
· Respiratory protection: Not required.
· Protection of hands:
The glove material has to be impermeable and resistant to the product/ the substance/ the preparation.
Selection of the glove material on consideration of the penetration times, rates of diffusion and the degradation· Material of gloves
The selection of the suitable gloves does not only depend on the material, but also on further marks of quality andvaries from manufacturer to manufacturer. As the product is a preparation of several substances, the resistanceof the glove material can not be calculated in advance and has therefore to be checked prior to the application.
· Penetration time of glove material
The exact break through time has to be found out by the manufacturer of the protective gloves and has to beobserved.
· Eye protection: Goggles recommended during refilling.

9 Physical and chemical properties· Information on basic physical and chemical properties· General Information· Appearance:
FluidForm:
According to product specification
Color:
Characteristic· Odor:
Not determined.
· Odour threshold:· pH-value:

N/A· Change in condition
Melting point/Melting range:
Boiling point/Boiling range:

Undetermined.
189 °C (372 °F)· Flash point:> 55 °C (> 131 °F)· Flammability (solid, gaseous):

Not applicable.

· Ignition temperature:
Decomposition temperature:

Not determined.

· Auto igniting:

Product is not selfigniting.

· Danger of explosion:

Product does not present an explosion hazard.

· Explosion limits:
Lower:
Upper:

Not determined.
Not determined.

· Vapor pressure:Not determined.

· Density:· Relative density· Vapour density· Evaporation rate

Not determined.
Not determined.
Not determined.
Not determined.
(Contd. on page 4)
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Trade name: Bioware Brite Cell Line MCF7-Red-FLuc(Contd. of page 3)· Solubility in / Miscibility withWater:

Fully miscible.

· Partition coefficient (n-octanol/water): Not determined.
· Viscosity:
Dynamic:
Kinematic:

Not determined.
Not determined.

· Solvent content:
Organic solvents:
VOC content:· Other information

5.0 %
5.0 %
No further relevant information available.

10 Stability and reactivity· Reactivity· Chemical stability· Thermal decomposition / conditions to be avoided: No decomposition if used according to specifications.
· Possibility of hazardous reactions No dangerous reactions known.
· Conditions to avoid No further relevant information available.
· Incompatible materials: No further relevant information available.
· Hazardous decomposition products: No dangerous decomposition products known.

11 Toxicological information· Information on toxicological effects· Acute toxicity:· Primary irritant effect:· on the skin: No irritant effect.
· on the eye: No irritating effect.
· Sensitization: No sensitizing effects known.
· Additional toxicological information:
The product is not subject to classification according to internally approved calculation methods forpreparations:
When used and handled according to specifications, the product does not have any harmful effects according toour experience and the information provided to us.
· Carcinogenic categories· IARC (International Agency for Research on Cancer)
None of the ingredients is listed.
· NTP (National Toxicology Program)
None of the ingredients is listed.
· OSHA-Ca (Occupational Safety & Health Administration)
None of the ingredients is listed.

12 Ecological information· Toxicity· Aquatic toxicity: No further relevant information available.
(Contd. on page 5)
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Trade name: Bioware Brite Cell Line MCF7-Red-FLuc(Contd. of page 4)· Persistence and degradability No further relevant information available.
· Bioaccumulative potential No further relevant information available.
· Mobility in soil No further relevant information available.
· Ecotoxical effects: N/A· Other information: N/A· Results of PBT and vPvB assessment· PBT: Not applicable.
· vPvB: Not applicable.
· Other adverse effects No further relevant information available.

13 Disposal considerations· Waste treatment methods· Recommendation: Must be specially treated adhering to official regulations.
· Uncleaned packagings:· Recommendation: Disposal must be made according to official regulations.
· Recommended cleansing agent: Water, if necessary with cleansing agents.

14 Transport information· UN-Number· DOT, ADR, ADN, IMDG, IATA

Void· UN proper shipping name
· DOT, ADR, ADN, IMDG, IATA

Void· Transport hazard class(es)· DOT, ADR, ADN, IMDG, IATA
· Class

Void· Packing group· DOT, ADR, IMDG, IATA

Void· Environmental hazards:· Marine pollutant:

No· Special precautions for user

Not applicable.

· Transport in bulk according to Annex II ofNot applicable.
MARPOL73/78 and the IBC Code· Transport/Additional information:

Not dangerous according to the above specifications.

· UN "Model Regulation":-15 Regulatory information· Safety, health and environmental regulations/legislation specific for the substance or mixture· Sara· Section 355 (extremely hazardous substances):
None of the ingredients is listed.
(Contd. on page 6)
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Trade name: Bioware Brite Cell Line MCF7-Red-FLuc(Contd. of page 5)· Section 313 (Specific toxic chemical listings):
None of the ingredients is listed.
· TSCA (Toxic Substances Control Act):
67-68-5 dimethyl sulfoxide· Proposition 65· Chemicals known to cause cancer:
None of the ingredients is listed.
· Chemicals known to cause reproductive toxicity for females:
None of the ingredients is listed.
· Chemicals known to cause reproductive toxicity for males:
None of the ingredients is listed.
· Chemicals known to cause developmental toxicity:
None of the ingredients is listed.
· Carcinogenic categories· EPA (Environmental Protection Agency)
None of the ingredients is listed.
· TLV (Threshold Limit Value established by ACGIH)
None of the ingredients is listed.
· NIOSH-Ca (National Institute for Occupational Safety and Health)None of the ingredients is listed.
· Chemical safety assessment: A Chemical Safety Assessment has not been carried out.

16 Other information
The information provided in this Material Safety Data Sheet is based on our present knowledge,
and believed to be correct at the date of publication. However, no representation is madeconcerning its accuracy and completeness. It is intended as guidance only, and is not to beconsidered a warranty or quality specification. All materials may present unknown hazards, andshould be used with caution. Although certain hazards are described, we cannot guarantee thatthese are the only hazards which exist. PerkinElmer, Inc. shall not be held
liable for any damage resulting from handling or from contact with the product.
· Date of preparation / last revision 06/08/2015 / · Abbreviations and acronyms:
ADR: Accord européen sur le transport des marchandises dangereuses par Route (European Agreement concerning the International
Carriage of Dangerous Goods by Road)
IMDG: International Maritime Code for Dangerous Goods
DOT: US Department of Transportation
IATA: International Air Transport Association
ACGIH: American Conference of Governmental Industrial Hygienists
EINECS: European Inventory of Existing Commercial Chemical Substances
ELINCS: European List of Notified Chemical Substances
CAS: Chemical Abstracts Service (division of the American Chemical Society)
NFPA: National Fire Protection Association (USA)
VOC: Volatile Organic Compounds (USA, EU)
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