The 29th Hot Spring Harbor International Symposium

Cutting Edge of Technical Innovations in Trans-Omics
Medical Institute of Bioregulation, Kyushu UniversityFebruary 6-7, 2020
Collaborative Research Station-I, Hospital Campus, Kyushu University, Fukuoka, JAPANTuesday, February 6, 2020
10:00 - 10:05

Opening Remarks:
Yusaku Nakabeppu (Director of Medical Institute of Bioregulation)

Session 1: Trans-Omics Technology (Proteomics)
Chair: Yoshihiro Baba
10:05-10:40

S-01: Yu-Ju Chen (Institute of Chemistry, Academia Sinica, Taiwan)
Proteogenomics Paves the Pathway to Next Generation Precision Medicinein Cancer(Presentation 30 minutes, Discussions 5 minutes)

10:40-11:05

S-02: Yasushi Ishihama (Kyoto University, Japan)
Shotgun Proteoformics to Unveil Human Proteome and Proteoforms(Presentation 20 minutes, Discussions 5 minutes)

11:05-11:30

S-03: Masaki Matsumoto (Niigata University, Japan)
iMPAQT ver. 2: New platform for absolute quantification of proteins ofinterest(Presentation 20 minutes, Discussions 5 minutes)

11:30-13:00

Lunch (meeting invited speakers only)

Session 2: Trans-Omics Technology (Metabolomics)
Chair: Atsushi Suzuki
13:00-13:35

S-04: Markus R Wenk (National University of Singapore, Singapore)
Translation of lipidomic technologies towards quantification of blood lipids(Presentation 30 minutes, Discussions 5 minutes)

13:35-14:00

S-05: Mitsutoshi Setou (Hamamatsu University, Japan)
Promoting trans-omics study through the project of “Imaging Platform”(Presentation 20 minutes, Discussions 5 minutes)

14:00-14:25

S-06: Yoshihiro Izumi (Kyushu University, Japan)
Inter-laboratory comparison of metabolite measurements for metabolomics
data integration(Presentation 20 minutes, Discussions 5 minutes)
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14:25-14:40

Group Photos

14:40-15:00

Coffee break

Session 3: Short Talks by Young Scientists
Chair: Shinichiro Sawa, Fumiyo Ikeda
Short talks of 15 minutes each(Presentation 10 minutes, Discussions 5 minutes)
15:00-15:15

Y-01: Kenichi Horisawa (Kyushu University, Japan)
Trans-omic analysis for metabolic remodeling during liver regeneration

15:15-15:30

Y-02: Chie Kikutake (Kyushu University, Japan)
Pan-cancer analysis for mutation hotspots in non-coding elements

15:30-15:45

Y-03: Fumiko Matsuzaki (Kyushu University, Japan)
Integrated analysis through multiple molecular layers: transomic network
dynamics

15:45-16:00

Y-04: Eriko Sumiya (Kyushu University, Japan)
Transcriptomic characterization of cells involved in fetal bone development

16:00-16:15

Y-05: Tsunaki Higa (Kyushu University, Japan)
Spatiotemporal Reprogramming of p57+ Quiescent Stem Cells Underlies
Regeneration and Neoplasia in the Intestinal Epithelium

16:15-16:30

Y-06: Kazufumi Kunimura (Kyushu University, Japan)
Identification of the novel environmental factor essential for M cellmaturation in Peyer’s patches

16:30-16:50

Coffee break

Session 4: Trans-Omics Analysis
Chair: Hiroyuki Kubota
16:50-17:25

S-07: Chang Matthew Wook (National University of Singapore,Singapore)
Reprogramming microbes to rewire host-microbiome interactions(Presentation 30 minutes, Discussions 5 minutes)

17:25-17:50

S-08: Fumio Matsuda (Osaka University, Japan)
Trans omics analysis of metabolic rewiring in inhibitor treated cancer cells
by integrating 13C metabolic flux and metabolome analyses(Presentation 20 minutes, Discussions 5 minutes)2

17:50-18:15

S-09: Chikara Furusawa (RIKEN / The University of Tokyo, Japan)
Toward prediction and control of microbial evolution: Analysis ofphenotypic constraints in laboratory evolution(Presentation 20 minutes, Discussions 5 minutes)

19:30-Dinner party (by invitation only)

Friday, February 7, 2020
Session 5: Single-Cell Analysis (Mass Spectrometry, Super-Resolution Imaging)
Chair: Seiji Okada
10:00-10:35

S-10: Ryan T. Kelly (Pacific Northwest National Laboratory, USA)One Cell at a Time: Sample Processing and Analysis Platform for In-Depth
Single-Cell Proteomics(Presentation 30 minutes, Discussions 5 minutes)

10:35-11:00

S-11: Takeshi Bamba (Kyushu University, Japan)
Development of single-cell molecular phenotyping technologies based on
mass spectrometry(Presentation 20 minutes, Discussions 5 minutes)

11:00-11:25

S-12: Yasushi Okada (RIKEN / The University of Tokyo, Japan)
Live cell imaging technologies for single-cell analysis – How can imaging
meets genomics?
(Presentation 20 minutes, Discussions 5 minutes)

11:25-13:00

Lunch (meeting invited speakers only)

Session 6: Single-Cell Analysis (Next Generation Sequencing)
Chair: Mikita Suyama
13:00-13:25

S-13: Itoshi Nikaido (RIKEN BDR, Japan)
RamDA-seq: a full-length total RNA-sequencing at a single-cell(Presentation 20 minutes, Discussions 5 minutes)

13:25-13:50

S-14: Tomoko Yoshino (Tokyo University of Agriculture & Technology,Japan)
Characterization of circulating tumor cells in gastric cancer patients basedon single-cell transcriptome analysis(Presentation 20 minutes, Discussions 5 minutes)

13:50-14:15

S-15: Yasuyuki Ohkawa (Kyushu University, Japan)
Chromatin integration labelling Technology for expanding multi-omics(Presentation 20 minutes, Discussions 5 minutes)

14:15-14:20

Closing Remarks: Takeshi Bamba (Kyushu University, Japan)
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