PROGRAMME@eapcct#eapcct2023

INDEX

GENERAL INFORMATION 						Committees 						4Social Programme					5Accreditation						5PRE-CONGRESS								Tuesday 23rd 						6MAIN CONGRESS 								Wednesday 24th 					9Thursday 25th						15Friday 26th 						22POSTERS 		
Wednesday 24th 					29Thursday 25th						38Friday 26th 							46CONGRESS SUPPORTERS & EXHIBITORS 			

3

54

GENERAL INFORMATIONThe 43th Congress of the European Association of Poisons Centers and Clinical Toxicologists (EAPCCT) has
been organized by the following committees:

EAPCCT SCIENTIFIC AND MEETINGS COMMITTEE
Lotte Høgberg (Chair of the Scientificand Meetings Committee)

Evangelia Liakoni

Maren Hermanns-Clausen (Vice-chair /Chairelect)

Bruno Mégarbane (Society Liaison)

Yvonne Lao
Raido Paasma

Ana Ferrer Dufol (EAPCCT President)

Dirk Steinritz

Laura Hondebrink (General Secretary)

Martin Wilks

Lonati Davide (Treasurer)David Wood

Horst Thiermann (Immediate Past President)

Christopher Yates (EAPCCT Local
Representative)

Paul Dargan (President-elect)
Nicola Bates (Abstracts Editor)

Mark Zammit

Kurt Anseeuw

Alexander Campbell (Congress Liaison)

Pardeep Jagpal
Piotr Maciej Kabata

EAPCCT BOARD

Pardeep Jagpal
Piotr Maciej Kabata
Gabija Laubner
Ophir Lavon
Emilio Salgardo
Ruben Thancoody
Nicola Bates (Board Secretariat)

Ana Ferrer Dufol (EAPCCT President)
Paul Dargan (President-elect)
Horst Thiermann (Immediate Past President)
Laura Hondebrink (General Secretary)
Lonati Davide (Treasurer)Mark Zammit (General Secretary /Treasurer support)

Anne-Marie Descamps

DELEGATE MEMBERS
Christopher Hoyte (President AACT)Louise Kao (President ACMT)
Hossein Hassanian-Moghaddam (APAMT ScientificOrganising Committee)
Carol DesLauriers (President AAPCC)
Robert S Hoffman (Co-Editor-in-Chief, Clinical Toxicology)
J. Allister Vale (Co-Editor-in-Chief, Clinical Toxicology)

CONGRESS SECRETARIAT
C/ Marià Cubí, 4 - Pral | 08006 · Barcelona
Tel. +34 932.388.777 · Fax: +34 932.387.488
eapcct2023@pacifico-meetings.com

4

SOCIAL PROGRAMMEWELCOME RECEPTIONWEDNESDAY 24TH MAY 2022 - 19:00h
The Welcome Reception will be held at the Bellver Castle on Wednesday 24th May 2023 from19:00h to 21:00h.

With the collaboration of the Ajuntament of Palma

The Bellver Castle is located close to the Congress venue. It can be reached on foot within 15
minutes from the venue. Bus service will be offered
CONFERENCE DINNERFRIDAY 26TH MAY 2023 - 20:00 to 23:00 hrs
The strategic location of the building is excellent because it is in thecenter of the city, close to the highways that connect the east and west
parts of the Island.
You will enjoy a typical Majorquian menú with the beautiful view fromthe rooftop of the auditorium.
More information: www.eapcct2023.com
ACCREDITATION
The application has been aproved to the UEMS EACCME® for CME accreditation for this event.
The congress has been granted 22 European CME credits (ECMEC®s) by the European Accreditation
Council for Continuing Medical Education (EACCME®).
NAME BADGE
Each delegate will receive a name badge when they register. This must be worn during the Congress
to gain entry to the lecture theatres, the dining hall (lunches) and at the Welcome Reception.
Registered accompanying persons will also receive a name badge, which they must wear at the
Welcome Reception and during lunch if this has been booked.

5Pre-Congress Tuesday 23rd May 2023
Toxic effects at therapeutic doses

TUESDAY 23rd MAY 2023
SALA MOZART
09:00-16:50		

Precongress Symposium: Toxic effects at therapeutic doses

09:00-09:10		

WELCOME & OPENING OF THE PRECONGRESS SYMPOSIUM
Moderator: Florian Eyer & Bruno Mégarbane
The frontiers between pharmacology and toxicology[10 min]Davide Lonati, Pavia, Italy
At the end of this session, the audience should be able to:• Explain differences between pharmacologists and toxicologist in the modern era.
During the presentations some clinical cases will be presented and discussed.

09:10-10:40 		
09:10-09:40
09:40-10:10
10:10-10:40

SECTION 1
Moderators: Florian Eyer & Bruno Mégarbane
Toxicity at therapeutic doses: should we still consider it as idiosyncratic?
[30 min]
Kim Dalhoff, Copenhagen, Denmark
Opioid analgesics: Did painkiller use cause an epidemic of fatalities?
[30 min]Rick Dart, Denver, CO, USA
Drug toxicity from pharmaceutical production processes[30 min]Mark Zammit, Msida, MaltaAt the end of this session, the audience should be able to:• Learn several ways to be poisoned after intake of a therapeutic medical drug dose.
• Understand drug toxicities from pharmaceutical production processes especiallyin relation to contaminants of such processes.
• Understand the effect of prescription opioids on substance use• Understand the effect of prescription opioids on drug-related mortality.
• Understand the societal impacts beyond mortality

11:00-12:30 		
11:00-11:30
11:30-12:00
12:00-12:30

SECTION 2
Moderators: Kim Dalhoff & Robin Ferner
Acetaminophen use during pregnancy: is it dangerous?
[30 min]Ruben Thanacoody, Newcastle, UK
Toxic hazards in pediatrics[30 min]
Lidia Martinez-Sanchez, Barcelona, Spain
Toxic hazards in geriatrics[30 min]Azzurra Schicchi, Pavia, Italy
At the end of this session, the audience should be able to:•Discuss the epidemiological evidence that paracetamol exposure during
pregnancy is harmful to the fetus•Discuss the most frequent toxic effects at therapeutic doses in pediatrics.
•Point out the mechanisms of toxicity and common exposure scenarios of
poisonings in older adults. Furthermore•Give several examples of poisoning prevention strategies to reduce thenumber of poisonings in the elderly.

712:30-13:30 		

LUNCH

13:30-15:30		

SECTION 3
Moderators: Ruben Thanacoody & Rick Dart

13:30-14:00

14:00-14:30

14:30-15:00

15:00-15:30

Therapeutic serotonergic agents: Is it serotonin toxicity?
[30 min]Angela Chiew, New South Wales, Australia
Chronic lithium overdose: particularities of management and outcome[30 min]
Dominique Vodovar, Poison Control Center Paris, France
Neuroleptic malignant syndrome in patients treated with antipsychotic drugs: is itpredictable and preventable?
[30 min]Florian Eyer, Munich, Germany
Metformin-associated versus metformin-induced lactic acidosis: is this differentiation
relevant in practice?
[30 min]
Bruno Mégarbane, Paris, France
At the end of this session, the audience should be able to:• Describe the clinical features and diagnosis of serotonin toxicity.
• Discuss the incidence of serotonin toxicity with therapeutic serotonergic
agent use.
• Understand the specificity of chronic lithium salt poisonings compared toacute and acute-on-chronic poisonings.
• Understand the specificity of the management of chronic lithium poisoning- know the prognosis of chronic lithium poisoning• Know and understand the epidemiological aspects and clinical manifestationsof NMS, aassociated medications, possible risk factors and treatment options.
• To understand the toxic consequences of metformin overdose• To know the difrerences in presentation and outcome between metforminassociated and metformin-induced lactic acidosis• To acknowledge the indications and effectiveness of extracorporeal
elimination enhancement of metformin

15:30-15:50 		

COFFEE BREAK

15:50-17:20 		

SECTION 4
Moderators: Angela Chiew & Mark Zammit

15:50-16:20
16:20-17:00

Therapeutic errors and toxicities from COVID-19 vaccines[30 min]Euan A Sandilands, Edinburgh, UK
Pharmacogenetic testing for everyone to prevent toxicities at therapeutic doses:
Pro/Con debate[30 min]
PRO: Alexander Jetter, Zürich, Switzerland
CON: Robin Ferner, Birmingham, UK
At the end of this session, the audience should be able to:• Provide an overview of the COVID-19 vaccines available in the UK, focussing
on adverse effects associated with therapeutic use and poison centre data
regarding overdose.
• Be informed about arguments for and against pre-emptive pharmacogenetic
testing for everyone.
• Understand the many factors that predispose people to adverse drug
reactions, summarised as GASPED - Genetic, Age, Sex, Physiologicaldifferences, Exogenous factors including drugs, and Diseases.

8MAIN CONGRESS
Wednesday 24th May 2023

WEDNESDAY 24th MAY 2023
SALA MAGNA
08:30-08:40		

WELCOME DAY 1 AND OPENING OF THE 43rd EAPCCT CONGRESS
Moderators: Ana Ferrer Dufol & Lotte Høgberg

08:40-10:40		

SYMPOSIUM: TOXICOLOGICAL ASPECTS OF WAR AND WARFARE
Moderators: Dirk Steinritz & Martin Wilks

08:40-09:20

PLENARY LECTURE: Preparedness for the Coming Radiation Disaster (Lessons
Learning from Hiroshima and Fukushima)[40 min]Nobuyuki Hirohashi, Hiroshima, Japan

09:20-10:00

PLENARY LECTURE: Toxicological aspects of war and warfare: the war in Ukraine[40 min]
Mykola Prodanchuk, Kyiv, Ukraine

10:00-10:20

Poisoning with cholinesterase inhibitors[20 min]
Niko Amend, Munich, Germany

10:20-10:40

Sulfur mustard poisoning - case report[20 min]
Kai Kehe, Munich, Germany
At the end of this session, the audience should be able to:• Explain why, although radiation disaster is rare, the knowledge and skills
needed to respond to it are easily lost and why we should learn from history
and plan for continuing education and training• Understand the new challenges of war for clinical toxicologists and poison
control centres.
• Describe the tasks of a toxicology centre during the war.
• Discuss the signs and symptoms of cholinesterase inhibitor poisoning, current
therapeutic concepts and novel treatment approaches.
• Give an overview about typical symptoms of sulfur mustard poisoning
illustrated by a case report.

10:40-11:20 		

COFFEE AND AUTHORS WITH POSTERSSALA MAGNA
11:20-13:00		

SYMPOSIUM: TOXIC TRAUMA – SPECIAL CONSIDERATIONS,INCLUDING: RISK OF SECONDARY EXPOSURE FOR MEDICAL PROFESSIONALSHELPING INTOXICATED PATIENTS AND TOXICOLOGY IN THE PREHOSPITALSETTING AND EMS.
Moderators: Horst Thiermann & David Wood

11:20-11:40

The 2006 London Polonium-210 Case: A Clinical Overview[20 min]Paul Dargan, London, UK

11:40-12:00

Intoxicated trauma patient!
[20 min]Dirk Steinritz, Munich, Germany

12:00-12:20

CBRN injuries, mass casualty intoxications[20 min]
Steve Emmett, Salisbury, UK10

12:20-12:40

Secondary chemical exposure of ambulance staff[20 min]
Ronald de Groot, Utrecht, The Netherlands

12:40-13:00

Laboratory verification of exposure to chemical warfare agents based on mass
spectrometric analysis of persistent biomarkers in biomedical samples[20 min]
Daan Noort, Den Haag, The Netherlands
At the end of this session, the audience should be able to:• Understand the clinical presentation of Polonium-210 toxicity in the 2016
London case.
• Be aware of significant disparities between C-B-RN situations,• Be familiar with general treatment and decontamination techniques,• Be informed of the difficulties associated with trauma injuries in CBRN scenarios.
• Be informed of the difficulties associated with trauma injuries in CBRN scenarios.
• Recognise the symptoms and signs of organophosphate nerve agent exposures,• Understand detection techniques and treatment options• Explain the limited risk for ambulance staff when treating or transportinga chemically contaminated patient and describe the measures that can betaken to minimise exposure.
• Give an introduction into the forensic analysis of biomedical samples ofvictims of incidents with chemical warfare agents

SALA MAGNA
14:15-15:15 		

ORAL PLATFORM: ORAL PRESENTATIONS 1
Moderators: Kurt Anseeuw & Ophir Lavon

14:15-14:30

Don’t shoot the messenger: an outbreak of lead poisoning at a UK firing range[15 min] Abstract #2 / Shortlisted for T&F Prize Best Oral Presentation
Aamna Warsi, Birmingham, UK

14:30-14:45

Inadvertent instillation of electronic cigarette liquid into the eyes
[15 min] Abstract #3
Ella Edwards, Cardiff, UK

14:45-15:00

Massive follow-up by short message service (SMS) of patients calling the Frenchpoison control centers (PCCs): a retrospective bicentric study[15 min] Abstract #4
Dominique Vodovar, Paris, France

15:00-15:15

N-acetylcysteine reduces acetaldehyde levels in binge alcohol drinking[15 min] Abstract #5
Miran Brvar, Ljubljana, Slovenia

SALA MAGNA
14:45-17:30		SYMPOSIUM: LESSONS LEARNED FROM LARGER EMERGENCIESSPILLS, WARFARE ETC)
Moderators: Fridtjof Heyerdahl & Dirk Steinritz(CHEMICAL

15:45-15:50

Introduction to the symposium and summary of emergency day[5 min]Moderators

15:50-16:10

Diagnostic opportunities after large scale exposure to nuclear detonations andradiological military or terrorist attacks.
[20 min]Matthias Port, Munich, Germany1116:10-16:30

16:30-16:50
16:50-17:10
17:10-17:30

Overview of the major food-borne toxic epidemics: From the Spanish Toxic Oil
Syndrome to the major pesticide outbreaks[20 min]Ana Ferrer-Dufol, Zargoza, Spain
Control of toxic emissions and health risk prevention in the La Palma Volcano outbreak[20 min]
Guillermo Burillo, Canary Islands, Spain
Management of chemical industrial accidents[20 min]Alex Harding, Huston, Texas USA
Opioids - naloxone pharmacokinetics – implications[20 min]Luke Yip, Denver, USA
At the end of this session, the audience should be able to:• Outline what diagnostic opportunities are available to triage or diagnosed
irradiated victims.
• Detail past foodborne toxic epidemics and outline strategies for prevention
and containment of such occurrences.
• Discuss unique challenges and considerations in the management of largescale industrial accidents• Discuss demographics and outcomes of industrial accidents.
• Reference several specific incidents in demonstrating key points aboutindustrial accident management• To know the Current situation (History of the La Palma Volcano, Detectedgases and health effects, Health actions in the population)

17:30		END OF SCIENTIFIC PROGRAMME CONGRESS DAY 1
19:00		WELCOME RECEPTION AT BELLVER CASTLE
18:45		SERVICE OF BUSES FOR THE WELCOME RECEPTIONSALA MOZART
08:30-10:40

NO PARALLEL SESSION

10:40-11:20 		

COFFEE AND AUTHORS WITH POSTERSSALA MOZART
11:20-13:00		
SYMPOSIUM: CORE CONTENT OF MEDICAL TOXICOLOGY (DIFFERENCES
BETWEEN EU COUNTRIES OR BETWEEN EU AND OTHER COUNTRIES
Moderators: Davide Lonati & Ruben Thanacoody
11:20-11:35
11:35-11:50
11:50-12:05
12:05-12:20

Medical toxicology contribution to policy decisions to protect human health[15 min]
Irina Zastenskaya, Bonn,Germany
Training in clinical toxicology: an Italian experience[15 min]
Carlo Locatelli, Pavia, Italy
Teaching pharmacotoxicology in a small island state[15 min]Janet Mifsud, Msida, MaltaSPI Training – a UK Perspective[15 min]Pardeep Jagpal, Birmingham, UK12

12:20-12:35
12:35-12:50
12:50-13:00

The educational program of toxicology in Australia[15 min]
Darren Roberts, Sydney, Australia
Postgraduate Diploma in Medical Toxicology: a first for Africa[15 min] Abstract #1
Catharina Elizabeth Du Plessis, Cape Town, South Africa
Discussion time
[10 min]
Moderators
At the end of this session, the audience should be able to:• Understand the range of activities used for training medical toxicologists inAustralia.
• Understand the challenges of being trained as a Specialist in Poisons
Information to work independently in a poison centre.
• Recognise the different approaches that can be implemented when training
new SPIs.
• Understand that beyond initial training, we are all always learning.
• Evaluate educational pathways.
• Highlight key education needs in clinical toxicology.
• Outline the place of medical toxicology has in WHO mandates and actions,and the various means by which tts roles could be enhanced in various
spheres of activity through collaboration with the WHO Regional Office forEurope.
• Be aware about: WHO activities in toxicology, previous assistance andsupport in a future that is expected.

13:00-13:45		

LUNCH

13:45-14:15		AUTHORS WITH POSTERSSALA MOZART
14:15-15:15		SYMPOSIUM: MEDITERRANEAN MARINE TOXICOLOGY
Moderators: Régis Bedry & Lotte Høgberg
14:15-14:40

14:40-15:05
15:05-15:15

The Mediterranean Sea and the Red Sea: origins, oceanography, climate: past,present, future[25 min]
Nadia Sénéchal, Bordeaux, France
The Suez Canal: what are the risks[25 min]
Régis Bedry, Bordeaux, France
Envenomation from non-indigenous marine species or native invaders ofMediterranean Sea: case-series from Pavia Poison Control Centre.
[10 min] Abstract 006
Giulia Scaravaggi, Pavia, Italy
At the end of this session, the audience should be able to:• Recognise that several natural and human factors contribute to theconstitution and recent increase of the Lessepsian invasion and alien species
in the Mediterranean Sea.
• Understand the hydrographic characteristics of these environments that are
more advantageous to Red Sea species compared to Mediterranean species.
• Give the basic elements on the role of human factors in this invasion and finallyto draw the trajectory of the system in the context of the climate change.
• Know what are the invasive marine species involved in the health risks• Diagnose the intoxications linked to these marine invaders• Prepare PC and emergency departments to recognise and treat these newintoxications.

1315:15-15:45 		

COFFEE AND AUTHORS WITH POSTERSSALA MOZART
15:45-17:30

SYMPOSIUM CONT.: MEDITERRANEAN MARINE TOXICOLOGY & ORAL PLATFORM:
ORAL PRESENTATIONS 2
Moderators: Lotte Høgberg & Dabor Résière

15:45-16:10

Venomous jelly fish in the Mediteranean sea - invasive and native, their blooming
and climate change impacts)[25 min]Azzurra Schicchi, Pavia, Italy

16:10-16:30

Experience of the French PC[20 min]
Luc De Haro, Marseille, France

16:30-16:50

Imported species and blind passenger – what to do when your poison center getsthe call ?!
[20 min]Sophie Gosselin, Montreal, Canada

16:50-17:00h

Discussion[10min]

17:00-17:15

A randomised controlled trial of antivenom for red-bellied black snake envenoming[15 min] Abstract #7 / Shortlisted for T&F Prize Best Oral Presentation
Geoffrey K Isbister, Newcastle, Australia

17:15-17:30

What drives the risks of being bitten by a viper? A fine spatial scale study in westernFrance[15 min] Abstract #8
Gaël Le Roux, Angers, France
At the end of this session, the audience should be able to:• Understand that the marine toxins are good indicator of the impact in marine
biotopes of global warming, and because of its geographical particularities
the Mediterranean Sea is one of the areas most affected by changes due by
global warming.
• Understand that the work of clinical toxicologists is directly impacted bythese upheavals: new forms of poisoning, new toxic species, new patients tobe treated … and it is only the beginning.
• Be aware of the most diffused jellyfish in the mediterranean sea and the clinicalconsequence of their sting. Additionally, all the possible new problems due
to invasive species will be evaluated from a clinical point of view, considering
the future risks due to climate changes.
• Devise a plan to obtain sound information on bites and stings from imported
species sustained by a returning travellers

17:30 		END OF SCIENTIFIC PROGRAMME CONGRESS DAY 1
19:00		WELCOME RECEPTION AT BELLVER CASTLE.
18:45 		SERVICE OF BUSES FOR THE WELCOME RECEPTION.

14

MAIN CONGRESS
Thursday 25th May 2023

THURSDAY 25th MAY 2023
SALA MAGNA
09:00-10:15		

YOUNG INVESTIGATORS AWARD (YIA)
Moderators: Knut Erik Hovda & Raido Paasma

09:00-09:05

Welcome and Introduction[5 min]Moderators

09:05-09:20

Performance of the ICU requirement score (IRS) in predicting the need for ICU
admission of intoxicated adult patients: the INTOXICATE study[15 min] Abstract #82
Samanta M Zwaag, Utrecht, Netherlands

09:20-09:35

The Emerging Cloud: a survey of vapers, their health, and the associated burden on
the UK health system[15 min] Abstract #83
Lachlan J Sund, London, UK

09:35-09:50

Clinical characterization and prognosis outcomes of carbon monoxide poisoning inSpain. The AMICO study[15 min] Abstract #84
Antonio F Caballero-Bermejo, Madrid, Spain

09:50-10:10

Toxicological consequences of mass tourism[20 min]Chris Yates, Palma de Mallorca, Spain

10:10-10:15

Presentation to the winner of the Young Investigator Award[5 min]Moderators

10:15-11:00

COFFEE AND AUTHORS WITH POSTERSSALA MAGNA
11:00-12:50		

SYMPOSIUM: NEW ANTIDOTES AND OLD ANTIDOTE FOR NEW TOXINS
Moderators: Yvonne Lao & Evangelia Liakoni

11:00-11:20

Modulation of nicotionic receptor function – an innovative approach for recovery ofparalyzed muscle function during cholinergic crisis[20 min]
Horst Thiermann, Munich, Germany

11:20-11:40

Fomepizole as a treatment for paracetamol overdose[20 min]James Dear, London, UK

11:40-12:00

Reversal of direct oral anticoagulation: is there a role for specific antidotes?
[20 min]Elias Bekka, Bern, Switzerland

12:00-12:20

Uridine triacetate for 5-FU and capecitabine toxicity[20 min]
Colette Degrandi, Zurich, Switzerland

12:20-12:35

Improving prognosis in Amanita phalloides intoxication – are two antidotes needed?
[15 min] Abstract #85
Daniela Pelclova, Prague, Czech Republic

12:35-12:50

Rivastigmine for the management of anticholinergic delirium: a case series[15 min] Abstract #86
Angela L Chiew, Randwick, Australia

16At the end of this session, the audience should be able to:• Understand that modulation of the nicotinic receptor is a rational approachto antagonize the neuromuscular paralysis induced by organophosphorus
compounds.
• Understand the theoretical value of fomepizole as an antidote for paracetamol
overdose.
• Discuss the role of specific and non-specific reversal agents in different
contexts of DOAC-associated bleeding and DOAC overdose.
• Describe the mechanism of action and potential applications of uridine
triacetate.

12:50-13:35 		

LUNCH

13:35-14:05 		

AUTHORS WITH POSTERSSALA MAGNA
14:05-16:00

SYMPOSIUM: MONITORING OF NEW PSYCHOACTIVE SUBSTANCES (NPS)INCLUDING: TOXICOVIGILANCE - COMMUNICATIONS/LINKS TO OTHERNATIONAL/EUROPEAN BODIES
Moderators: Maren Hermanns-Clausen & David Wood

14:05-14:25

Drug Monitoring in Europe: Recent developments and novel monitoring tools[20 min]Isabelle Giraudon, Lisbon, Portugal

14:25-14:35

Poisons Centre Monitoring of NPS[10 min]Laura Hondebrink, Utrecht, The Netherlands

14:35-14:55

NPS Monitoring in Australia: Recent developments and novel monitoring tools[20 min]Shaun Greene, Melbourne, Australia

14:55-15:10

The EU Early Warning System on new psychoactive substances: 25 years of early
warning and response in Europe[15 min] Abstract #88
Joanna De Morais, Lisbon, Portugal

15:10-15:25

Drug Checking Services for people who use drugs - NPS market monitoring & harm
reduction[15 min]Laura Smit-Rigter, Utrecht, The Netherlands

15:25-15:40

ChemSex context and substance abuse: a case series[15 min] Abstract #89
Lucia Bernasconi, Pavia, Italy

15:40-16:00

Monitoring of NPS in patient blood samples: machine-learning combined withactivity-based bioassays[20 min]Christophe Stove, Ghent, Belgium

17

At the end of this session, the audience should be able to:• Learn more about how NPS markets are currently being monitored in the
Netherlands and how warnings are being issued once an extra hazardous
substance has been detected.
• Describe the unique monitoring aspects of a multi-disciplinary network of
hospitals and health care professionals that enable the rapid translation of
acute bedside toxicology into harm reduction interventions within the wider
community.
• To be able to tell what activity-based screening entail.
• To know the potential role that may be played by activity-based testing for
toxicology screening purposes.
• To know how activity-based testing may contribute to a better understandingof the toxicity of new psychoactive substances and the role played by thesesubstances in intoxications.
• To learn about Drug monitoring in Europe, coordinated by the EMCDDA
together with the Reitox network of National Focal Points, and to learn about
the recent developments and novel monitoring tools.
16:00-16:30

COFFEE AND AUTHORS WITH POSTERSSALA MAGNA
16:30-17:15
17:15 -17:45

ORAL PLATFORM: ORAL PRESENTATIONS&NEWS FROM THE WORKGROUPS: UPDATE FROM THE COLLABORATIVEWORKGROUP GROUP
Moderators: Pardeep Jagpal & Irma de Vries

16:30-16:45

From heroin to prescription opioids: opioid poisoning in Australia over the last
three decades[15 min] Abstract #91 / Shortlisted for T&F Prize Best Oral Presentation
Katherine Isoardi, Brisbane, Australia

16:45-17:00

Naloxone requirements of confirmed para-fluorofentanyl exposures in emergency
department patients with illicit opioid overdose[15 min] Abstract #92
Rachel E Culbreth, Phoenix, USA

17:00 -17:15

Illicit substance use requiring chemical sedation: a prospective cohort study of1125 patients presenting to Emergency Departments with analytically confirmed
psychoactive substance exposure[15 min] Abstract #93
Sarah Hodgson, Melbourne, Australia

17:15-17:45

Tox collaborative introduction[5 min]Chris Yates, Palma de Mallorca, Spain

17:35-17:45

QT[10 min]Ingrid Berling, New South Wales, Australia

17:45-17:55

Paracetamol[10 min]Angela Chiew, New South Wales, Australia
At the end of this session, the audience should be able to:• Outline the progress and findings of the Toxicology Collaborative’s work on
QT / Paracetamol

18

17:55

END OF SCIENTIFIC PROGRAMME CONGRESS DAY 2

18:00

EAPCCT GENERAL ASSEMBLY IN SALA MOZARTSALA MOZART
09:00-10:15

NO PARALLEL SESSION

10:15-11:00 		

COFFEE AND AUTHORS WITH POSTERSSALA MOZART
11:00-12:50

SYMPOSIUM: BOTULISM
Moderators: Maren Hermanns-Clausen & Thomas Zilker

11:00-11:15

Botulism - historic input introduction: Justinus Kerner: Scientist, poet and visionary[15 min]Thomas Zilker, Munich, Germany

11:15-11:35

Botulinum toxins and their toxicological mechanism[20 min]
Mandy Knüpfer, Munich, Germany

11:35-11:55

Challenges and recent progress in the detection of botulinum neurotoxins[20 min]
Brigitte Dorner, Berlin, Germany

11:55-12:15

Botulism: Clinical features and therapy[20 min]David Steindl, Charité Berlin, Germany

12:15-12:35

Infant botulism: Special challenge in diagnostics and therapy[20 min]Davide Lonati, Pavia, Italy

12:35-12:50

Emergency provision of botulism-antitoxin-heptavalent serum throughout the
National Health System: the Italian experience of the National Antidotes Stockpile[15 min] Abstract #87
Guilia Scaravaggi, Pavia, Italy
At the end of this session, the audience should be able to:• Understand Botulinum toxins, their structure and mechanisms of action.
• Understand the clinical findings of botulism in adults and summarize theclinical management and recommended treatment options.
• Understand botulinum neurotoxins as a highly diverse group of molecules
and to identify suitable detection approaches with their individual pros andcons.
• Know the history of Justinus Kerner, German poet and physician and his
contribution to our understanding of Botulism.
• Infant botulism is a rare intoxication involving infant with age lower than
1 year. Scientifica data showed a real underreporting of this intoxication.
During the presentations some clinical cases will be presented and discussed
alco about different treatment approach.

12:50-13:35 		

LUNCH

13:35-14:05 		AUTHORS WITH POSTERS

19

SALA MOZART
14:05-16:00

SYMPOSIUM: THE MITOCHONDRIA IN TOXICOLOGY
Moderators: Davide Lonati & Tonny Studsgaard

14:05-14:25

Mitochondrial toxicology exemplified in Wilson disease[20 min]Hans Zischka, Munich-Neuherberg, Germany

14:25-14:45

Emerging mitochondrial mechanisms mediating drug-induced cardiotoxicity[20 min]Peter de Paepe, Ghent, Belium

14:45-15:05

Hepatotoxicity in fatty liver disease linked to obesity: role of mitochondrial
dysfunction induced by different xenobiotics[20 min]Bernard Fromenty, Rennes, France

15:05-15:25

Mitochondrial disorders in propofol-related infusion syndrome[20 min]
Dylan de Lange, Utrecht, The Netherlands

15:25-15:45

Glyoxylate and small redox molecules to rescue mitochondrial toxicity[20 min]Randall T. Peterson, Salt Lake City, Utah, USA

15:45-16:00

Acute tolfenpyrad poisoning reported to Taiwan National Poison Center: a caseseries[15 min] Abstract #90
Nai-Yu Chen, Taipei City, Taiwan
At the end of this session, the audience should be able to:• Know that Mitochondrial damage in human disease is not uniform.
• Unravelling the damaging mechanisms is key to develop targeted treatments• Understand the basic principles of mitochondrial mechanisms mediating
drug-induced cardiotoxicity.
• Understand the pathophysiological mechanism of propofol-induced
mitochondrial dysfunction.
• Become familiar with the metabolic perturbations caused by cyanide
poisoning and learn how cyanide toxicity can be rescued in animal models by
modulating mitochondrial redox balance.
• Explain how mitochondria differ, how mitochondrial damage occurs and why
it is not uniform, and discuss why therapeutic approaches need to take thespecific mode of damaging events into account.

16:00-16:30		

COFFEE AND AUTHORS WITH POSTERSSALA MOZART
16:30-17:50

ORAL PLATFORM: ORAL AND SHORT ORAL PRESENTATIONS
Moderators: Betty Chan & Katrin Faber

16:30-16:45

Sodium nitrite: an emerging public health concern in the United Kingdom[15 min] Abstract #94
Ella Edwards, Cardiff, UK

16:45-17:00

Collaborative public health responses to suicide prevention: sodium nitrite[15 min] Abstract #95
Jared Brown, Sydney, Australia

17:00-17:15

Insulin kinetics in high dose insulin therapy – a human randomized controlled trial[15 min] Abstract #178
Søren Bøgevig, Copenhagen, Denmark20

17:15-17:25

Accidental clozapine ingestions are of concern[10 min] Abstract #96
Colette Degrandi, Zurich, Switzerland

17:25-17:35

Randomized crossover study comparing the pharmacokinetics of two different
nicotine salt concentrations and free-base nicotine using an open vape pod system[10 min] Abstract #98 / Shortlisted for T&F Prize Best Oral Presentation Samuel
Christen, Bern, Switzerland

17:35-17:45

Variation in sensitivity to diethylene glycol poisoning can be explained by variationin tissue DGA uptake due to expressional differences in dicarboxylate transporters[10 min] Abstract #99
Kenneth McMartin, Shrevenport, USA

17:45-17:55

Quetiapine overdose, good or bad, or just more of the same?
[10 min] Abstract #100
Geoffrey K Isbister, Newcastle, Australia

17:55

END OF SCIENTIFIC PROGRAMME CONGRESS DAY 2

18:00

EAPCCT GENERAL ASSEMBLY

21

MAIN CONGRESS
Friday 26th May 2023

FRIDAY 26th MAY 2023
SALA MAGNA
09:00-10:05		SPECIAL SESSION: LOUIS ROCHE LECTURE
Moderators: Ana Ferrer-Dufol
09:00-09:15

Introduction and presentation of the Louis Roche Lecturer[15 min]Ana Ferrer-Dufol, Zaragoza, Spain, EAPCCT President

09:15-10:00

You can check out any time you like - but you can never leave[45 min]Martin Wilks, Basel, Switzerland
At the end of this session, the audience should be able to:• Discuss the potential role of changes to paraquat formulations in order tomitigate toxic effects after ingestion

10:00-10:05

Time to move from plenary to parallel sessions

SALA MAGNA
10:05-11:05		ORAL PLATFORM: ORAL PRESENTATIONS 4
Moderators: Sally Bradberry & Bob Hoffman
10:05-10:20

Addictive potential of recreational nitrous oxide use[15 min] Abstract #174
Laura Hondebrink, Utrecht, The Netherlands

10:20-10:35

Gamma-hydroxybutyrate (GHB) withdrawal syndrome treated with GHB: the use of
sodium oxybate in GHB-dependence[15 min] Abstract #175
Søren Bøgevig, Copenhagen, Denmark

10:35-10:50

Co-exposure to gamma-hydroxybutyrate (GHB) attenuates stimulant effects ofmethamphetamine to a greater degree than co-exposure to benzodiazepines[15 min] Abstract #176
Shaun Greene, Melbourne, Australia

10:50-11:05

Investigation of differences in the neurorespiratory effects after oral administrationof γ-hydroxybutyrate versus γ-butyrolactone with a pharmacokinetic modelling
approach in the rat[15 min] Abstract #177
Bruno Mégarbane, Paris, France

11:05-11:35		

COFFEE AND AUTHORS WITH POSTERS

23

SALA MAGNA
11:35-12:55

SYMPOSIUM: MENTAL WELLNESS AND RESILIENCE OF CLINICAL TOXICOLOGISTSAND POISON CENTRE STAFF SYMPOSIUM
Moderators: Alex Campbell & Sophie Gosselin

11:35-11:40

11:40-11:55

11:55-12:10

12:10-12:35

12:35-13:00

Introduction to the session[5 min]Chris Hoyte, Denver, USA
Take care of yourself in order to be able to take care of others[15 min]Ana Serrano, Zaragoza, Spain
Diversity, Equity, and Inclusion: Why It Matters To Toxicology[15 min]Garry Winkler, Houston-Texas USA
Depression, Burnout and Suicide: Well-being for Toxicologists[25 min]
Greg Carter, Newcastle, Australia
Panel Discussion[25 min]
Moderators and Speakers
At the end of this session, the audience should be able to:• Identify risk factors of burnout for healthcare providers particularly as it
relates to the specialty of toxicology.
• Recognise the symptoms and signs of burnout in toxicology clinicians
and understand the basic principles of prevention and treatment aimed atmaintenance and or renewal of mental wellbeing.
• Identify the importance of Diversity, Equity, and Inclusion in the practice of
Toxicology, both for patients and providers.
• Understand the importance of addressing this situation at two levels. The firstlevel is based on psychoeducation in identifying warning signs of psychologicaldistress and self-care, and the second level involves specialized services thatprovide specific attention through accompaniment and facilitation of stressmanagement strategies.

12:55-13:40 		

LUNCH

13:40-14:10 		AUTHORS WITH POSTERSSALA MAGNA
14:10-15:10

SPECIAL SESSION: CLINICAL CASE SESSION
Moderators: Paul Dargan & Lotte Høgberg

14:10-14:40

14:40-15:10

Panel:

Gassed and off legs – not a laughing matter[30 min]Klara De Baerdemaeker, London, UK
Where to go – when the pressure drops[30 min]
Søren Bøgevig, (Copenhagen, Denmark)
Ingrid Berling (Newcastle, Australia)
Bob Hoffman (New York, USA)
Kurt Anseeuw (Sint-Katelijne-Waver, Belgium)
At the end of this session, the audience should be able to:• Understand the mechanisms of nitrous oxide related neuropathy• Describe the management of nitrous oxide related neuropathy24

15:10-15:40		

COFFEE AND AUTHORS WITH POSTERSSALA MAGNA
15:40-16:40

SPECIAL SESSION: EAPCCT FELLOWS’ LECTURE
Moderators: Rick Dart & Allister ValeThe US fentanyl epidemic: dynamics in supply, use and policy response
Daniel Ciccarone, San Francisco, USA
At the end of this session, the audience should be able to:• Describe the four waves of mortality in the 20-year US overdose crisis• Discuss changes in supply and how they related to fentanyl and polysubstanceuse• Identify policy and medical strategies to assist in reducing overdose deaths

16:40 		END OF SCIENTIFIC PROGRAMME CONGRESS DAY 3 & CLOSING OF THE CONGRESS
20:00 		CONGRESS DINNERSALA MOZART
09:00-10:05

NO PARALLEL SESSIONSALA MOZART
10:05-11:05

SPECIAL SESSION: BEST PAPER
Moderators: Piotr Kabata & Darren Roberts

10:05-10:20

Paper 1
[15 min]Temporal trends in calls for suicide attempts to poison control centers in France
during the COVID-19 pandemic: a nationwide study.
Jollant F, Blanc-Brisset I, Cellier M, Ambar Akkaoui M, Tran VC, Hamel JF, Piot MA,
Nourredine M, Nisse P; French Poison Center Control Research Group; Hawton K,
Descatha A, Vodovar D.
Eur J Epidemiol. 2022 Sep;37(9):901-913. doi: 10.1007/s10654-022-00907-z. PMID:
36040638
Arjen Koppen, Utrecht, The Netherlands

10:20-10:35

Paper 2[15 min]
Andexanet Alfa for Reversal of Factor Xa Inhibitors in Intracranial Hemorrhage:
Observational Cohort Study.
Rauch S, Müller HP, Dreyhaupt J, Ludolph AC, Kassubek J, Althaus K.
J Clin Med. 2022 Jun 13;11(12):3399.
doi: 10.3390/jcm11123399. PMID: 35743469.
Mark Pucci, Birmingham, UK

10:35-10:50

Paper 3[15 min]Diagnosis, Management, and Prevention of Button Battery Ingestion in Childhood: A
European Society for Paediatric Gastroenterology Hepatology and Nutrition Position
Paper.
Mubarak A, Benninga MA, Broekaert I, et al.
J Pediatr Gastroenterol Nutr. 2021 Jul 1;73(1):129-136. doi: 10.1097/
MPG.0000000000003048. PMID: 33555169
Cathelijne Lyphout, Ghent, Belgium

25

10:50-11:05

Paper 4[15 min]
ToxNet: an artificial intelligence designed for decision support for toxin prediction.
Zellner T, Romanek K, Rabe C, Schmoll S, Geith S, Heier EC, Stich R, Burwinkel H,
Keicher M, Bani-Harouni D, Navab N, Ahmadi SA, Eyer F.
Clin Toxicol (Phila). 2023 Jan;61(1):56-63.
doi: 10.1080/15563650.2022.2144345. PMID: 36373611
Emma Morrison, Edinburgh, UK
At the end of this session, the audience should be able to• Identify the most important articles from recent years 2021-2023, picked by
the speakers, that:• Most changed/challenged your practice, or taught you something completely
new or unexpected• Most improved your understanding of toxicological mechanisms, or was mostinformative/inspiring regarding Poison Center activities

11:05-11:35		

COFFEE AND AUTHORS WITH POSTERSSALA MOZART
11:35 -12:55

SYMPOSIUM: ORGAN TRANSPLANTATION FROM INTOXICATED DONORS
Moderators: Rana Biary & Paul Dargan

11:35-11:55

Organ Transplantation in Intoxicated Patients – is there a network and criteria to be
used[20 min]
Giovanna Panarello, Palermo, Italy

11:55-12:15

Poisoned donors after brain death or cardiocirculatory death: the challenges ofdiagnosis and graft outcome
Philippe Hantson, Brussels, Belgium

12:15-12:35

Organ transplantation from methanol poisoned donors[20 min]Yvonne Lao, Oslo, Norway

12:35-12:55

Organ pransplantation following intoxication with psychoactive substances[20 min]David Wood, London, UK
At the end of this session, the audience should be able to:• Recognize the major differences between poisoned donors after brain deathor cardiocirculatory death.
• Discuss the choice of diagnostic tools in both situations.
• Compare the graft outcome, and to discuss ethical issues.
• Understand the potential for organ donation to and from those withpsychoactive toxicity.
• Provide an overview of the experience of using patients with methanol
poisoning as organ donors

12:55-13:40 		

LUNCH

13:40-14:10 		AUTHORS WITH POSTERS

26

SALA MOZART
14:10-15:10		ORAL PLATFORM: ORAL PLATFORM PRESENTATIONS 5
Moderators: Alex Campbell & Kai Knudsen
14:10-14:25

Paracetamol medication errors are associated with a high risk of hepatotoxicity inchildren aged 0-6 years: a retrospective cohort study[15 min] Abstract #97
Alaa A Daoud, Copenhagen, Denmark

14:25-14:40

A prospective validation study of a clinical decision instrument for head computed
tomography in intoxicated patients presenting to the emergency department[15 min] Abstract #179 / Shortlisted for T&F Prize Best Oral Presentation
Richard Mcnulty, Sydney, Australia

14:40-14:55

Reversible and transient thrombocytopenia induced by snake C-type lectinlike
proteins (snaclecs) from nose-horned viper venom / Shortlisted for T&F Prize Best
Oral Presentation[15 min] Abstract #180
Miran Brvar, Ljubljana, Slovenia

14:55-15:10

Investigation of oxycodone-induced neuro-respiratory effects in a rat model usinga PK/PD approach[15 min] Abstract #181
Bruno Mégarbane, Paris, France

15:10-15:40 		

COFFEE AND AUTHORS WITH POSTERS

15:40-16:40 		NO PARALLEL SESSION
16:40		CLOSING OF THE CONGRESS IN SALA MOZARTSALA MAGNA
16:50 -17:30		EAPCCT FELLOWS MEETING[40 min]20:00 			CONGRESS DINNER

27

Posters

Posters 24th May 2023
EPIDEMIOLOGY OF POISONING
009

Has the re-scheduling of modified-release paracetamol in Australia affected the frequency of
overdoses?
Michaela Ryan, Andis Graudins, Anselm Wong.
Department of Medicine, School of Clinical Sciences at Monash Heath, Monash University, Victoria,
Australia.

010

Increase in deliberate self-poisonings by adolescents reported to the National Poisons
Information Center during the second year of the COVID-19 pandemic
Arjen Koppen, Ilze MJ Thoonen, Agnes G Van Velzen, Claudine C Hunault, Dylan W De Lange, Saskia
J Rietjens.
Dutch Poisons Information Center, University Medical Center Utrecht, Utrecht, Netherlands; Dutch
Poisons Information Center, Intensive Care, University Medical Center Utrecht, Utrecht, Netherlands.

011

One-year single hospital study of acute poisonings in Israel
Konstantin Brusin1, Meital Zikry Deitch1, Elena Kishenevsky1, Arkady Shklyar1, Gennady Bregman1,
Hasan Agbaria1, Haytham Attoun1, Knut Erik Hovda2.
1
Kaplan Medical Center, Rehovot, Israel; 2Dep. Acute Medicine Oslo University Hospital, Oslo, Norway.

012

The impact of socioeconomic status on toxicological exposures in pregnancy
Will Heise1, Stephanie Christensen2, Laura Mercer1.
1
University of Arizona College of Medicine Phoenix, Phoenix, United States; 2Kaiser Permanente, San
Diego, United States.

013

Acute paracetamol poisoning in children: a retrospective study
Julia V Radenkova-Saeva, Miroslava T Petkova.
Toxicology Clinic, University Hospital for Emergency Medicine “NI Pirogov”, Sofia, Bulgaria.

014

Results of a toxicovigilance program in a tertiary hospital of the Community of Madrid, fromJanuary 2020 to August 2022
Arturo Gómez, Javier Guijarro, Rosario M Torres, Rosa Mayayo, Lucía Díaz, Alberto M Borobia,
Antonio J Carcas, Mikel Urroz.
La Paz University Hospital, Madrid, Spain.

015

Adolescent poisonings reported to the UK National Poisons Information Service (NPIS): a 6.5 year
study
Annie Watt1, Thomas M Caparrotta1, Ruben HK Thanacoody2, Laurence A Gray3, Sally Bradberry4,
Gillian Jackson1, Euan A Sandilands1.
1
NPIS Edinburgh, Edinburgh, United Kingdom; 2NPIS Newcastle, Newcastle Upon Tyne, United
Kingdom; 3NPIS Cardiff, Cardiff, United Kingdom; 4NPIS Birmingham, Birmingham, United Kingdom.

016

Increased risk of major adverse cardiovascular events in middle-aged obese patients receiving
Chinese herbal medicine: a nationwide cohort study in Taiwan
Yi-Ju Ho1, Wen-Chieh Yang2, Te-I Weng3.
1
National Taiwan University Hospital, Taipei, Taiwan; 2Taipei Veterans General Hospital Hsinchu
Branch, Hsinchu, Taiwan; 3Department of Forensic Medicine, College of Medicine, National Taiwan
University, Taipei, Taiwan.

017

No laughing matter: trends in nitrous oxide misuse in the United States during the COVID-19
pandemic
Ryan J Cole, Rita Farah, Nathan P Charlton.
University of Virginia Health, Charlottesville, United States.

019

Medication errors in the neonatal intensive care unit
Ophir Lavon, Amit Wasserman, Yamit Musai.
Carmel Medical Center, Haifa, Israel.

29

020

Belgian Poison Centre: annual overview 2021
Dominique Vandijck1, Jonas Van Baelen1, Eline Bekaert1, Evelien De Smet1, Jonas Moens2, Pamela
Selway1, Régine Pire1, Sarah Desmaele1, Karolien De Leener1, Anne-Marie Descamps1.
1
Belgian Poison Centre, Brussels, Belgium; 2Belgian, Brussels, Belgium.

021

Severity and outcome in acutely intoxicated patients with elevated creatine kinase
Aleksandra Babulovska, Daniela Chaparoska, Natasha Simonovska, Zanina Pereska, Niko Bekjarovski,
Irena Jurukov, Afrodita Berat-Huseini, Kristin Kostadinoski, Kiril Naumoski.
Clinical Centre, University Clinic of Toxicology, Medical Faculty, Sts Cyril and Methodius University in
Skopje, Republic of North Macedonia, Skopje, Macedonia.

022

Are nicotine pouches a toxicological problem in Austria?
Susanna Dorner-Schulmeister, Tara Arif.
Poisons Information Centre, Vienna, Austria.

023

National reports of e-liquid poisoning received by French Poison Control Centers from July 2019
to December 2020
Fanny Pelissier1, Juliette Bloch2, Cécilia Solal2, Nicolas Franchitto3.
1
Centre Antipoison et Toxicovigilance Occitanie, Centre Hospitalier et Universitaire de ToulousePurpan, Toulouse, France; 2ANSES, Maisons-Alfort, France; 3Service d’Addictologie Universitaire,
Centre Hospitalier de Toulouse-Purpan, Toulouse, France.

025

Characterization of exposures in preschoolers reported to a Chilean Poison Control Center in
2020.
Antonia Sateler1, Marli Bettini2, Lorena Silva2, Patricio Medel3, Pablo Iturra1, Francisco Figueroa2,
Lisette Irarrázabal4, Juan Carlos Ríos5.
1
Programa de Farmacología y Toxicología Pontificia Universidad Católica de Chile, Santiago, Chile;
2
Centro de Información Toxicológica Pontificia Universidad Católica de Chile (CITUC), Santiago, Chile;
3
Centro de Información Toxicológica Pontificia Universidad Católica de Chile (CITUC), Programa deFarmacología y Toxicología Pontificia Universidad Católica de Chile, Escuela de Enfermería Pontificia
Universidad Católica de Chile, Santiago, Chile; 4Escuela de Enfermería Pontificia Universidad Católica
de Chile, Santiago, Chile; 5Centro de Información Toxicológica Pontificia Universidad Católica deChile (CITUC), Programa de Farmacología y Toxicología Pontificia Universidad Católica de Chile,
Departamento de Laboratorios Clínicos Pontificia Universidad Católica de Chile, Santiago, Chile.

026

Impact of COVID-19 pandemic in rising suicide attempts through intentional acute poisoning in
teenagers in Chile. Analysis of the major Chilean Poison Control Center data
Patricio Medel-Jara1, Lorena Silva2, Marli Bettini2, Claudio Retamal2, Francisco Figueroa2, Sandra
Solari3, Juan Carlos Ríos3.
1
Centro de Información Toxicológica Pontificia Universidad Católica de Chile (CITUC), Programa deFarmacología y Toxicología Pontificia Universidad Católica de Chile, Escuela de Enfermería Pontificia
Universidad Católica de Chile, Santiago, Chile; 2Centro de Información Toxicológica y de Medicamentos(CITUC), Facultad de Medicina, Pontificia Universidad Católica de Chile, Santiago, Chile; 3Centro deInformación Toxicológica y de Medicamentos (CITUC), Facultad de Medicina, Pontificia Universidad
Católica de Chile, Programa de Farmacología y Toxicología Pontificia Universidad Católica de Chile,
Departamento de Laboratorios Clínicos, Escuela de Medicina, Pontificia Universidad Católica deChile, Santiago, Chile.

027

Proportion of poisoned patients at the Emergency Department with QTc prolongation, based on
different correction formulas
Irma S Van Den Hengel-Koot, Saskia J Rietjens, Douwe Dekker, Dylan W De Lange, Laura Hondebrink.
University Medical Center Utrecht, Utrecht University, Utrecht, Netherlands.

028

Electronic clinical files of patients in the emergency department. Usefulness as tools for
toxicosurveillanceFrancisco J Ruiz-Ruiz1, Mario Angulo-Artal2, Ana Serrano-Ferrer3, Rafael Marron-Tundidor4, Ana
Ferrer-Dufol5.
1
Emergency Department. Unit of Clinical Toxicology. Hospital Clínico Universitario, Zaragoza, Spain;
2
Universidad de Zaragoza, Zaragoza, Spain; 3Hospital Clínico Universitario, Zaragoza, Spain; 4Servicio
Aragones de Salud, Zaragoza, Spain; 5Unit of Clinical Toxicology. Hospital Clinico Universitario,
Zaragoza, Spain.

30

029

The rise in edible marijuana related calls following cannabis decriminalization: one poison
center’s experience
Rita Farah, Will R. Goodrich, Ryan J. Cole, Christopher P. Holstege.
Division of Medical Toxicology, Department of Emergency Medicine, University of Virginia School of
Medicine, Charlottesville, United States.

031

The diagnosis and treatment of cannabinoid hyperemesis syndrome
Arón Misa García1, Álvaro Medina Guerrero2, Marina Fages Pérez3, Yolanda Ibáñez Borau4, Beatriz
Calderón Hernanz2, Montserrat Vilanova Boltó2, Miguel Agudo García4.
1
Hospital Pharmacy Department, Hospital Universitario de Ourense, Ourense, Spain; 2Hospital
Pharmacy Department, Hospital Universitario Son Llàtzer, Palma de Mallorca, Spain; 3Hospital
Pharmacy Department, Hospital de la Línea, Cádiz, Spain; 4Emergency Department, Hospital
Universitario Son Llàtzer, Palma de Mallorca, Spain.

032

Aetiology and clinical severity of carbon monoxide poisoning in Germany
Nina Glaser, Michael Reuser, Kathrin Begemann.
German Federal Institute for Risk Assessment, Berlin, Germany.

033

Analysis of suicide attempts by chemicals in the years 2017-2021 gathered in the Spanish
Toxicosurveillance ProgramAna Serrano1, Francisco Ruiz2, Ana Ferrer3.
1
Psiquiatría Hospital Clínico universitario, Zaragoza, Spain; 2Urgencias, Zaragoza, Spain; 3Toxicología,
Zaragoza, Spain.

034

Pandemic and post-pandemic intoxications in the intensive care unit (ICU) of a general public
hospital
Clara Serrano Ferrer1, Laura Sanchez2, Sara Gomez3, Elena Lacruz4, Ana Serrano5, Ana Ferrer Dufol6,
Begoña Zalba7.
1
ICU. “Príncipe de Asturias” Hospital, Alcalá de Henares, Spain; 2ICU. Clinical University Hospital,
Zaragoza, Spain; 3ICU. Clinic University Hospital, Zaragoza, Spain; 4ICU. Clinic University Hospital,
Zaragoza, Spain; 5Psychiatric Unit. Clinic University Hospital, Zaragoza, Spain; 6Unit of Clinical
Toxicology. Clinic University Hospital, Zaragoza, Spain; 7Intensive Care Unit.Clinic University Hospital,
Zaragoza, Spain.

035

Hospital-treated deliberate self-poisoning in Azerbaijan: epidemiological features and clinicaloutcomes
Ismayil Afandiyev1, Jamil Afandiyev2.
1
Clinical Toxicology, Baku, Azerbaijan; 2Department of Psychiatry, Baku, Azerbaijan.

036

Intentional ingestions in children and adolescents as a worldwide phenomenon
Anna A Celentano1, Alvin A Bronstein2, Marcello M Ferruzzi1, Fabrizio F Sesana1, Giovanni M Milanesi1,
Francesco F Scaglione1.
1
Milan Poison Control Center, ASST Grande Ospedale Metropolitano Niguarda, Milan, Italy;
2
Emergency Medical Services & Injury Prevention System Branch Hawaii State Department of Health
Leahi Hospital -Honolulu, Milan, United States.

037

Marijuana exposures reported to the US Poison Centers
Saumitra Rege, Will Goodrich, Christopher Holstege.
The University of Virginia, Charlottesville, United States.

038

Exposures and suspected intoxications in children aged 0-14 years: real-world data from an
Italian reference poison control centre before and during the COVID-19 pandemic
Valentina Brilli1, Giada Crescioli1, Francesco Gambassi2, Andrea Missanelli2, Alessandra Ieri2, Cecilia
Lanzi2, Alessandra Pistelli2, Arianna Totti2, Alfredo Vannacci1, Guido Mannaioni1, Niccolò Lombardi1.
1
Department of Neurosciences, Psychology, Drug Research and Child Health, Section of Pharmacology
and Toxicology, University of Florence, Florence, Italy, Florence, Italy; 2Medical Toxicology Unit andPoison Control Center, Careggi University Hospital, Florence, Italy, Florence, Italy.

31

039

Drug poisoning: data analysis from the Poison Control Center in Florence, Italy (2018-2020)
Francesco Gambassi1, Guido Mannaioni2, Cecilia Lanzi1, Alessandra Pistelli1, Simone Sartori2, Andrea
Burgalassi2, Brunella Occupati2, Alessandra Ieri2.
1Medical Toxicology Unit and Poison Center, Careggi University Hospital, Florence, Italy;
2
NEUROFARBA Department, Pharmacology and Toxicology Section, University of Florence, Viale
Pieraccini 6, 50139, Florence, Italy.

MONITORING OF NEW PSYCHOACTIVE SUBSTANCES (NPS)040

Self-reported xylazine exposure and experiences: a mixed methods study of Reddit users
Anthony Spadaro1, Jeanmarie Perrone1, Lakamana Sahithi2, Karen O’connor1, Rachel Wightman3,
Jennifer Love4, Abeed Sarker2.
1
University of Pennsylvania, Philadelphia, United States; 2Emory University, Atlanta, United States; 3Brown
University, Providence, United States; 4Mount Sinai Health System, New York City, United States.

OCCUPATIONAL POISONING
041

Circumstances of acute occupational exposure to acids and alkalis reported to the Dutch
Poisons Information Center
Anja PG Wijnands1, Irma De Vries1, Tim Verbruggen1, Maxim Carlier1, Dylan W De Lange2, Saskia J Rietjens1.
1
Dutch Poisons Information Center, University Medical Center Utrecht, University Utrecht,
Netherlands; 2Dutch Poisons Information Center, University Medical Center Utrecht, University
Utrecht, Department of Intensive Care Medicine, University Medical Center Utrecht, University
Utrecht, Utrecht, Netherlands.

042

Reports on occupational poisoning cases with detergents and cleaning agents to the German
Federal Institute for Risk Assessment from 2012 to 2021
Kathrin Begemann, Nina Glaser, Michael Reuser, Herbert Desel.
German Federal Institute for Risk Assessment, Berlin, Germany.

043

A protracted, low dose dermal exposure and a short-lasting, high dose dermal exposure toaniline caused methaemoglobinaemia in two workplace accidents at the same facility.
Anja J Huusom1, Kristian Andersen2, Steen K Barnung2, Lotte C G Høgberg3.
1
The Danish Poisons Information Centre; Depatment of Occupational and Environmental Medicine,
Copenhagen University Hospital - Bispebjerg and Frederiksberg, Copenhagen, Denmark;2
Department of Anaesthesiology, Centre of Head and Orthopaedics, Copenhagen University Hospital- Rigshospitalet, Copenhagen, Denmark; 3The Danish Poisons Information Centre; Department ofAnaesthesia and Intensive Care, Copenhagen University Hospital - Bispebjerg and Frederiksberg,
Copenhagen, Denmark.

044

Why does this gas keep killing??? Rotten egg smell does not protect you!
Paula E C Hammer1, Lotte C G Høgberg2.
1Danish Poison Information Centre; Department of Occupational and Environmental Medicine,
Copenhagen, Denmark; 2Danish Poison Information Centre; Department of Anaesthesia and Intensive
Care, Copenhagen, Denmark.

PESTICIDE POISONINGS
045

Isolated nicotinic toxicity and urinary discoloration following unintentional pediatric carbaryl
ingestion
Marlis Gnirke1, Joshua Bloom1, Ramya J Sivasubramanian2, David Sardar2, Anna Mai3, Samara
Soghoian1, Robert S Hoffman1, Sage W Wiener3.
1
Division of Medical Toxicology, Ronald O. Perelman Department of Emergency Medicine, NYU
Grossman School of Medicine, New York City, United States; 3Department of Pediatrics, SUNY
Downstate Health Sciences University, Brooklyn, United States; 3Department of Emergency Medicine,
SUNY Downstate Health Sciences University, Brooklyn, United States.

32

046

Evaluation of biocidal product enquiries to the Austrian Poisons Information Centre, 2020
Tara Arif, Dieter Genser.
Poisons Information Centre, Vienna, Austria.

047

Impact of plasma concentrations of glyphosate, its metabolite and polyethoxylated tallow
amine surfactants on clinical outcomes following glyphosate poisoning
Shuping Qiang1, Fahim Mohamed2, Nicholas A Buckley3, Lorraine Mackenzie1, Michael S Roberts4.
1
University of South Australia Clinical and Health Sciences, University of South Australia, Adelaide,
Australia; Therapeutics Research Centre, Basil Hetzel Institute for Translational Health Research,
The Queen Elizabeth Hospital, Adelaide, Australia; 2South Asian Clinical Toxicology Research
Collaboration, University of Peradeniya, Peradeniya, Sri Lanka; Faculty of Medicine and Health,Sydney Pharmacy School, Pharmacology, University of Sydney, Sydney, Australia; 3Translational
Australian Clinical Toxicology (TACT) Research Group, Biomedical Informatics and Digital Health,
Faculty of Medicine and Health, The University of Sydney, Sydney, Australia; 4Therapeutics ResearchCentre, The University of Queensland Diamantina Institute, The University of Queensland, Brisbane,
Australia; University of South Australia Clinical and Health Sciences, University of South Australia,
Adelaide, Australia.

048

Death of two infants due to misuse of a pesticide product
Esther Feistkorn, Nina Glaser, Michael Reuser, Kathrin Begemann.
German Federal Institute for Risk Assessment, Berlin, Germany.

049

Paraquat poisoning exposures: a South African Poisons Information Helpline experience
Catharina E Du Plessis1, Carine J Marks1, Cindy R Stephen2.
1
Stellenbosch University, Cape Town, South Africa; 2University of Cape Town, Cape Town, South Africa.

050

Consultations regarding Plant Protection Products 2019 - 2021 to the Austrian Poisons Information
CentreTara Arif, Helmut Schiel.
Poisons Information Centre, Vienna, Austria.

051

Bromoxynil and 2-methyl-4-chlorophenoxyacetic acid (MCPA) poisoning resulting in death
Pramod Chandru, Dushan Jayaweera.
Department of Clinical Pharmacology & Toxicology, Western Sydney Health, Sydney, Australia.

052

Case series of acute 4,6-dinitro-o-cresol (DNOC) self-poisoning
Gordana Vukovic Ercegovic, Natasa Perkovic Vukcevic, Olivera Potrebic, Jasmina Jovic Stosic,
Dragana Djordjevic, Milica Zlatkovic, Slavica Vucinic.
National Poison Control Center, Military Medical Academy, Belgrade, Serbia.

053

Hydrogen cyanamide exposure: a case series study from Italy
Monica Carnovale1, Lucia Bernaconi1, Davide Lonati2, Azzurra Schicchi2, Valeria M Petrolini2,
Bendetta Brolli1, Valentina Negrini1, Olha Maystrova2, Francesca Crema3, Carlo A Locatelli2.
1
Pavia Poison Control Centre - National Toxicology Information Centre - Clinical and Experimental
Lab, Toxicology Unit, Istituti Clinici Scientifici Maugeri IRCCS. Postgraduate School of Pharmacology
and Clinical Toxicology, University of Pavia, Pavia, Italy; 2Pavia Poison Control Centre - National
Toxicology Information Centre - Clinical and Experimental Lab, Toxicology Unit, Istituti Clinici
Scientifici Maugeri IRCCS, Pavia, Italy; 3Department of Internal Medicine and Therapeutics, Sectionof Pharmacology, University of Pavia, Pavia, Italy.

PLANT AND MUSHROOM POISONING
054

Status epilepticus in a child intoxicated by Psilocybe mexicana and Cannabis sativa
Natanael Del Ángel González, Yaneli A González Chávez, Jorge G Pérez Tuñón, Mayré I Bautista
Albíter, Arturo G Ponce De León.
Centro Toxicológico Hospital Ángeles Lomas, Huixquilucan, Mexico.

33

055

Root-rhythmia: tejocote (Crataegus mexicana) ingestion associated dysrhythmia
Stephen Petrou, John Keller, Craig G. Smollin.
University of California San Francisco, San Francisco, California, USA; California Poison Control
System – San Francisco Division, San Francisco, California, USA, San Francisco, United States.

056

Suicidal Digitalis purpurea poisoning in an adultAnna-Mariia Termälä, Riikka Palo.
Poison Information Center, University of Helsinki and Department of Emergency Medicine andServices, Helsinki University Hospital, Helsinki, Finland.

057

Detectable serum digoxin concentration following exploratory lily of the valley ingestion in an
asymptomatic child
Marlis Gnirke1, Nicholas Otts2, Mary Ann Howland3, Mark K Su4.
1
Division of Medical Toxicology, Ronald O. Perelman Department of Emergency Medicine, NYU
Grossman School of Medicine, New York City, United States; 2Division of Pediatric Emergency
Medicine, Westchester Medical Center, Valhalla, United States; 3St. John’s University College of
Pharmacy and Health Sciences, Queens, United States; 4New York City Poison Control Center, NewYork City, United States.

058

Poisoning with cardiac glycoside-containing plants reported to the UK National Poisons
Information Service: a 7-year study
Victoria A Eagling1, Ruben HK Thanacoody2, Laurence A Gray3, Sally Bradberry4, Euan A Sandilands1.
1
NPIS Edinburgh, Royal Infirmary of Edinburgh, Edinburgh, United Kingdom; 2NPIS Newcastle, Regional
Drug and Therapeutics Centre, Newcastle upon Tyne, United Kingdom; 3NPIS Cardiff, University Hospital
Llandough, Cardiff, United Kingdom; 4NPIS Birmingham, City Hospital, Birmingham, United Kingdom.

059

Modern day shamanism: a case of repeated ayahuasca consumption in metropolitan France
documented by hair and nails analysis
Gaël Le Roux1, Jérémy Lecot1, Chloé Bruneau1, Florian Hakim2, Alexandr Gish2, Jean-Michel Gaulier2.
1
Centre antipoison Grand Ouest, Angers, France; 2Unité fonctionnelle de Toxicologie, Lille, France.

060

Surprising lack of symptoms after potentially dangerous colchicine poisoning from Gloriosa
superba (glory lily) tea
Erik Borski1, Michael Deters1, Katja Schulz2, Joerg Pietsch3, Anne Stuerzebecher1.
1
Poisons Information Centre Erfurt, Erfurt, Germany; 2Technische Universität Dresden, Dresden,
Germany; 3Technische Universität Dresden, Erfurt, Germany.

061

Another victim of omelettes: a case of severe mushroom intoxication with muscarine detection
Chloé Bruneau, Jérémy Lecot, Rebecca Vinas, Marie Deguigne, Estelle Flament, Gaël Le Roux.
Centre Antipoison Grand Ouest, Angers, France.

062

Crataegus mexicana (tejocote) exposure in a 23 month-old, with signs of cardiotoxicity, withnormalization of their ECG after administration of digoxin immune FabNoah G Berland1, Molly Kaminsky2, Trevor Cerbini1, Cynthia Santos1, Diane Calello1, Howard Greller1,
Christopher Meaden1, Lewis Nelson1.
1
Rutgers NJMS - NJPIES, Newark, United States; 2Morristown Medical Center, Morristown, United States.

063

Ceylon leadwort (Plumbago zeylanica) induced contact dermatitis and skin erosions
Yaopan Liao.
Chang-Hua Hospital, Chang-Hua County, Taiwan.

064

Metabolic acidosis from ingestion of plant roots mimicking cyanide poisoning: a case report ofacute Dioscorea hispida poisoning
Kai-Wen Cheng.
Department of Clinical Toxicology & Occupational Medicine, Taipei Veterans General Hospital, Taipei
City, Taiwan.

065

Aflatoxicosis at the intersection of modern agriculture and public health
Shahnaz Sonya Rashid1, S Eliza Dunn2.
1
Toxikon Consortium, Chicago, United States; 2Bayer Crop Science, St. Louis, United States.

34

066

Acute cyanide poisoning due to ingestion of the seeds containing amygdalin in Slovenia, 20192021
Ana Mavrič1, Gašper Razinger1, Lucija Šarc1, Miran Brvar2.
1
Centre of Clinical Toxicology and Pharmacology, University Medical Centre Ljubljana, Ljubljana,
Slovenia; 2Centre of Clinical Toxicology and Pharmacology, University Medical Centre Ljubljana andCentre for Clinical Physiology, Faculty of Medicine, University of Ljubljana, Ljubljana, Slovenia.

067

Anticholinergic syndrome due to mushroom poisoning: a case series
Benedetta Brolli1, Cristina Grazioli1, Valentina Negrini1, Azzurra Schicchi2, Valeria M Petrolini2, Davide
Lonati2, Francesca Crema3, Carlo A Locatelli2.
1
Pavia Poison Control Centre - National Toxicology Information Centre - Clinical and Experimental
Lab, Toxicology Unit, Istituti Clinici Scientifici Maugeri IRCCS, Pavia Institute, Postgraduate School of
Pharmacology and Clinical Toxicology, University of Pavia, Pavia, Italy; 2Pavia Poison Control Centre- National Toxicology Information Centre - Clinical and Experimental Lab, Toxicology Unit, Istituti
Clinici Scientifici Maugeri IRCCS, Pavia Institute, Pavia, Italy; 3Department of Internal Medicine andTherapeutics, Section of Pharmacology, University of Pavia, Pavia, Italy.

TOXIC TRAUMA – SPECIAL CONSIDERATIONS(EXPOSURE OF MEDICAL STAFF / RE-INTOXICATION / MANAGEMENT IN PRE-HOSPITAL SETTINGS AND EMS)
068

Activation code of severe acute intoxication (CodiTox): A protocol for detection, prioritisationand treatment of the seriously intoxicated patient
Maria Àngels Gispert-Ametller1, Juliana González-Londoño2, Raquel Aguilar-Salmerón3, Miguel
Galicia-Paredes4, Santiago Nogué-Xarau5, Lídia Martínez-Sánchez6, Albert Obiols-González7, AugustSupervía-Caparrós8.
1
Emergency Department. Hospital Universitari Doctor Josep Trueta, Girona, Spain; 2Intensive Care
Unit. Hospital Santa Caterina., Girona, Spain; 3Pharmacy Service. Hospital Universitari Doctor Josep
Trueta, Girona, Spain; 4Emergency Department. Hospital Clínic, Barcelona, Spain; 5Fundación
Española de Toxicología Clínica, Barcelona, Spain; 6Emergency Department. Hospital Sant Joande Déu, Barcelona, Spain; 7Sistema d’Emergències Mèdiques, Barcelona, Spain; 8Emergency
Department. Hospital del Mar, Barcelona, Spain.

TOXICOLOGICAL ASPECTS OF WAR AND WARFARE
069

In vivo evaluation of novel target pathways for the development of delayed cardiovascular
dysfunction after sulfur mustard exposure
Jacqueline S Rioux, Carly A Johnson, Julie W Harral, Mohamed S Basiouny, Leslie A Bloomquist,
Shenali R Uragoda, Denver Armstrong, Jasmine Martinez, Carl W White, Livia A Veress.
University of Colorado, Department of Pediatrics, Denver, United States.

TOXINOLOGY (BITES, STINGS, ANTIVENOM ETC.) / MEDITERRANEANMARINE TOXICOLOGY070

Viper envenomation in Greece - experience from the Greek Poison Information Center during
the year 2022
Vasiliki Mougiou, Myrto Bonataki, Vasiliki Kotsira, Ioanna-Maria Sykara, Vasiliki Papathanasiou, Eleni
Basanou, Angeliki Kalostou.
Greek Poison Information Center, Pan. and Aglaia Kyriakou Children’s Hospital, Athens, Greece.

35

071

An Australian regional review of the use and location of snake antivenom
Amy Thomson, Jared Brown.
NSW Poisons Information Centre, Sydney, Australia.

072

Viper bite: a case report
Victoria Lobo Antuña1, Celia Piñero1, Marta Lobo Antuña2, Benjamin Climent1.
1
Consorcio Hospital General Universitario de Valencia, Valencia, Spain; 2Hospital Universitario
Fundación Jiménez Díaz, Madrid, Spain.

073

The utility of hyperbaric oxygen therapy in severe necrotizing infection secondary to suspected
spider bite: a case report
Anna A Celentano1, Giovanni G Sesana2, Carmela C Graci2, Paolo P Pantini3, Marcello M Ferruzzi1,
Francesco F Scaglione1.
1
Milan Poison Control Center, ASST Grande Ospedale Metropolitano Niguarda, Milan, Italy; 2Hyperbaric
Medicine Center, ASST Grande Ospedale Metropolitano Niguarda, Milan, Italy; 3Civic Museum of
Natural Sciences “E. Caffi”, Bergamo, Bergamo, Italy.

074

Compartment syndrome after Italian viper bite: two case reports
Lucia Bernasconi1, Monica Carnovale1, Davide Lonati2, Benedetta Brolli1, Valentina Negrini1, Cristina
Grazioli1, Francesca Crema3, Carlo A Locatelli2.
1
Pavia Poison Control Centre - National Toxicology Information Centre - Clinical and Experimental
Lab, Toxicology Unit, Istituti Clinici Scientifici Maugeri IRCCS. Postgraduate School of Pharmacology
and Clinical Toxicology, University of Pavia, Pavia, Italy; 2Pavia Poison Control Centre - National
Toxicology Information Centre - Clinical and Experimental Lab, Toxicology Unit, Istituti Clinici
Scientifici Maugeri IRCCS, Pavia, Italy; 3Department of Internal Medicine and Therapeutics, Sectionof Pharmacology, University of Pavia, Pavia, Italy.

075

Failure of viper antivenom therapy and the need for an effective antidote: an Italian pediatriccase series
Lucia Bernasconi1, Davide Lonati2, Azzurra Schicchi2, Benedetta Brolli1, Cristina Grazioli1, Valentina
Negrini1, Monica Carnovale2, Francesca Crema3, Carlo A Locatelli2.
1
Pavia Poison Control Centre - National Toxicology Information Centre - Clinical and Experimental
Lab, Toxicology Unit, Istituti Clinici Scientifici Maugeri IRCCS. Postgraduate School of Pharmacology
and Clinical Toxicology, University of Pavia, Pavia, Italy; 2Pavia Poison Control Centre - National
Toxicology Information Centre - Clinical and Experimental Lab, Toxicology Unit, Istituti Clinici
Scientifici Maugeri IRCCS, Pavia, Italy; 3Department of Internal Medicine and Therapeutics, Sectionof Pharmacology, University of Pavia, Pavia, Italy.

076

Portuguese man o’ war: heart attack! First case of Physalia physalis cardiotoxicity reported in
Italy
Valentina Negrini1, Cristina Naturale2, Valentina Negrini1, Monica Carnovale1, Cristina Grazioli1, Elena
Mattiuzzo2, Giulia Scaravaggi2, Valeria M Petrolini2, Francesca Crema3, Carlo A Locatelli2.
1
Pavia Poison Control Centre - National Toxicology Information Centre - Clinical and Experimental
Lab, Toxicology Unit, Istituti Clinici Scientifici Maugeri IRCCS, Pavia Institute. Postgraduate School of
Pharmacology and Clinical Toxicology, University of Pavia, Pavia, Italy; 2Pavia Poison Control Centre- National Toxicology Information Centre - Clinical and Experimental Lab, Toxicology Unit, Istituti
Clinici Scientifici Maugeri IRCCS, Pavia Institute, Pavia, Italy; 3Department of Internal Medicine andTherapeutics, Section of Pharmacology, University of Pavia, Pavia, Italy.

077

Fatal stings
Wui Ling Chan.
Consultant, KTPH A&E, Singapore, Singapore.

VETERINARY TOXICOLOGY (POISONING IN ANIMALS)
078

Ivermectin toxicosis in dogs: circumstances, clinical signs and severity of poisoning
Nicola Bates, Zoe Tizzard, Nick Edwards.
Veterinary Poisons Information Service, London, United Kingdom.

36

079

Nitroscanate toxicosis in cats and dogs
Nicola Bates, Zoe Tizzard, Nick Edwards.
Veterinary Poisons Information Service, London, United Kingdom.

PHARMACEUTICAL POISONING
080

Use of rivastigmine to treat scopolamine toxicity: a case report
Samantha S. Klein, Robert S Hoffman.
Division of Medical Toxicology Ronald O. Perelman Department of Emergency Medicine, New York
University School of Medicine, New York, United States.

081

Status epilepticus in the setting of an intentional ingestion of propranolol: a case report
Samantha S. Klein1, Mark K Su2.
1
Division of Medical Toxicology Ronald O. Perelman Department of Emergency Medicine, New York
University School of Medicine, New York, United States; 2New York City Poison Control Center,
Department of Health and Mental Hygiene, New York, United States.

212

Cathartic catharsis: hypermagnesemia toxicity leading to respiratory paralysis, secondary tocathartic abuse
Stephen Petrou, Craig G. Smollin.
University of California San Francisco, San Francisco, California, USA; California Poison Control
System – San Francisco Division, San Francisco, California, United States.

37

Posters 25th May 2023
BOTULISM
101

Wound botulism following intravenous methamphetamine use
Balveena K Dhaliwal1, Andrew Henderson2, Jessica Qiu2, Naren Gunja3.
1
Western Sydney Toxicology Services, Kellyville, Australia; 2Department of Neurology, Westmead
Hospital, New South Wales, Australia; 3Western Sydney Toxicology Services, Sydney, Australia.

102

A case of foodborne botulism type E
Karolien De Leener1, Bram Depelseneer2, Jonas Moens1, Dominique Vandijck1, Anne-Marie Descamps1.
1
Belgian Poison Centre, Brussels, Belgium; 2ZNA Middelheim, Antwerp, Belgium.

MISCELLANEOUS
103

Severe neurological sequelae of carbon monoxide poisoning
Balveena K Dhaliwal1, Chong Wong2, Naren Gunja1.
1
Western Sydney Toxicology Services, NSW, Australia; 2Department of Neurology, Westmead
Hospital, NSW, Australia.

104

Factors associated with hospitalization for acute recreational drug toxicity
Viktoria T Aasgaard, Maria Abrahamsen, Mette Brekke, Odd Martin Vallersnes.
University of Oslo, Oslo, Norway.

105

The association between alcohol co-ingestion and clinical outcome of deliberate self-poisoning
patients visiting the emergency department
Seon Hee Woo, Gyu Won Kim, Woon Jeong Lee, Dae Hee Kim, Jun Young Lee.
The Catholic University of Korea, Incheon St. Mary’s Hospital, Incheon, South Korea.

106

Baron von Münchausen in a bullet proof vest
Marc Stevens1, Erik Lindeman1, Andreas Blomgren2.
1
Swedish Poisons Information Centre, Solna, Sweden; 2Swedish Medical Products Agency, Uppsala, Sweden.

107

Recreational use of nitrous oxide – a growing concern in Europe
Joanna De Morais1, Leon Van Aerts2, Michael Evans-Brown1, Ana Gallegos1, Rachel Christie1, Rita Jorge1,
Thomas Néfau1, Gregorio Planchuelo1, Roumen Sedefov1, Caroline Victorri-Vigneau3, Rasa Povilanskienė4,
Kari Grasaasen5, Dorte Fris Palmqvist6, Deirdre Mongan7, Nicki Killeen8, António Óscar Duarte9.
1
European Monitoring Centre for Drugs and Drug Addiction, Lisbon, Portugal; 2Section Pharmacology,
Toxicology and Biotechnology, College ter Beoordeling van Geneesmiddelen, Medicines Evaluation
Board, Utrecht, Netherlands; 3Clinical Pharmacology Department, Center for Evaluation andInformation on Pharmacodependence – Addictovigilance, Nantes University Hospital, Nantes,
France; 4Drug precursors control and risk assessment division, Drug, Tobacco and Alcohol Control
Department of Lithuania, Vilnius, Lithuania; 5Danish Health Authority, Copenhagen, Denmark;6
Department of Anesthesia and Intensive Care, The Danish Poisons Information Centre, Copenhagen
University Hospital Bispebjerg, Copenhagen, Denmark; 7Health Research Board, Dublin, Republic of
Ireland; 8Health Service Executive, Dublin, Republic of Ireland; 9Divisão de Relações Internacionais,Serviço de Intervenção nos Comportamentos Aditivos e nas Dependências, Lisbon, Portugal.

108

Predicting the need for Intensive Care Unit (ICU) admission in acutely intoxicated adult patientsat the Emergency Department (ED)Claudine C Hunault1, Samanta M Zwaag1, Irma S Van Den Hengel-Koot1, Saskia J Rietjens1, Laura
Hondebrink1, Douwe Dekker2, Dylan W De Lange3.
1
Dutch National Poisons Information Centre (DPIC), University Medical Center Utrecht, Utrecht,
Netherlands; 2Dutch National Poisons Information Centre (DPIC), University Medical Center Utrecht;
Department of Emergency Medicine, University Medical Center Utrecht, Utrecht, Netherlands;
3
Dutch National Poisons Information Centre (DPIC), University Medical Center Utrecht; Department
of Intensive Care Medicine, University Medical Center Utrecht, Utrecht, Netherlands.

38

109

Gamma-hydroxybutyrate (GHB) intoxication: clinical diagnosis versus laboratory findings
Didrik Skjelland1, Benedicte M Jørgenrud2, Karsten Gundersen3, Mari Asphjell Bjørnaas4, Mette
Brekke1, Vivian M Dalaker1, Håvard Furuhaugen2, Odd M Vallersnes1.
1
Department of General Practice, University of Oslo, Oslo, Norway; 2Section of Drug Abuse Research,
Department of Forensic Sciences, Oslo University Hospital, Oslo, Norway; 3Department of Medicine,
Lovisenberg Diaconal Hospital, Oslo, Norway; 4Department of Acute Medicine, Oslo University
Hospital Ullevaal, Oslo, Norway.

110

A febrile syndrome with a broad differential diagnosis
Juan Ortega Pérez1, Meritxell Vidal Borràs2, Carlos Rafael Álvarez Ferrer1, Catalina Homar Amengual3,
María Del Carmen Rodríguez Ocejo1, Maria Codinach Martín2, Bernardino Comas Díaz1, Jordi
Puiguriguer Ferrando1.
1
Physician, Palma de Mallorca, Spain; 2Physician, Girona, Spain; 3Nurse, Palma de Mallorca, Spain.

201

Alcohol intoxication in adolescence can affect the behavior of young people in the future
Juan Ortega Perez1, Laura Riera Lopez2, Jordi Puiguriguer Ferrando1, Catalina Homar Amengual3,
Meritxell Vidal Borras4, Maria Codinach Martin4, Bernardino Barcelo Martin5, Bernardino Comas Diaz1.
1
Physician, Palma de Mallorca, Spain; 2Psychology, Palma de Mallorca, Spain; 3Nurse, Palma de
Mallorca, Spain; 4Physician, Girona, Spain; 5Clinical Analysis, Palma de Mallorca, Spain.

111

Iatrogenic medication errors - still a problem
Mandy Gollmann, Michael Deters, Anne Stürzebecher.
Poison Information Centre Erfurt, Erfurt, Germany.

112

Severity of voluntary and accidental methanol intoxication associated with methylated spirit
ingestion: a retrospective study in a French poison control center.
Geraldine Meyer1, Dominique Savary2, Marie Deguigne1, Alexis D’Escatha1.
1
Poison Control Center, Angers, France; 2Emergency department, Angers, France.

113

Palytoxin poisoning during the pandemicÁgnes Bakos, Ildikó Urbán.
Péterfy Sándor Hospital, Budapest, Hungary.

114

Necrotizing fasciitis in a parenteral drug user
Victoria Lobo Antuña1, David Rodrigo Domiguez1, Marta Lobo Antuña2, Sofia Russo Botero1, Miriam
Ripoll Martínez1, Benjamin Climent1.
1
Consorcio Hospital General Universitario de Valencia, Valencia, Spain; 2Hospital Fundación Jiménez
Díaz, Madrid, Spain.

115

Cocaine body packer: a case report
Gabija Valauskaite1, Haris Jakavicius2, Gabija Laubner-Sakalauskiene2, Robertas Badaras2.
1
Department of Intensive Care Medicine, Lithuanian University of Health Sciences, Kaunas, Lithuania;
2
Toxicology center, Republic Vilnius university hospital, Vilnius, Lithuania.

116

The teratogenic risk of caffeine in pregnancy
Mariapina Gallo, Georgios Eleftheriou, Andrea Giampreti, Lorella Faraoni, Marco Cirronis, Maria Gioia
Contessa, Giuseppe Bacis.
Bergamo Poison Control Center, ASST Papa Giovanni XXIII, Bergamo, Italy, Bergamo, Italy.

117

Massive caffeine ingestion without severe poisoning: a case report
Georgios Eleftheriou1, Raffaella Butera2, Mariapina Gallo2, Andrea Giampreti2, Lorella Faraoni2, Marco
Cirronis1, Maria Gioia Contessa1, Eliana Margutti3, Giuseppe Bacis1.
1Bergamo Poison Control Center, ASST Papa Giovanni XXIII, Bergamo, Italy, Bergamo, Italy; 2Poison
Control Center, ASST Papa Giovanni XXIII, Bergamo, Italy, Bergamo, Italy; 3Emergency Department,
ASST Papa Giovanni XXIII, Bergamo, Italy, Bergamo, Italy.

39

118

Autoimmune diseases related to cocaine use: a case series
Macarena L Míguez Del Águila1, Gemma Alvarez Martinez1, Antoni Castro Guardiola1, Nuria Vilanova
Anducas1, Angels Gispert Ametller2, Ana Merino Ribas3, Carolina Lorencio Cardenas4, Mercè Alsius Suñer5.
1
Department of Internal Medicine, Hospital Universitari Dr. J. Trueta de Girona, Girona, Spain;
2
Emergency Department, Hospital Universitari Dr. J. Trueta de Girona, Girona, Spain; 3Departmentof Nephrology, Hospital Universitari Dr. J. Trueta de Girona, Girona, Spain; 4Department of Intensive
care, Hospital Universitari Dr. J. Trueta de Girona, Girona, Spain; 5Department of clinical analysis,
Hospital Universitari Dr. J. Trueta de Girona, Girona, Spain.

119

Severe complications associated with cocaine abuse requiring intensive care unit (ICU) admission
Clara Serrano Ferrer1, Angela Ruiz García2, Diego Beltrán Hernandez1, Ana Oñoro Morales2, Alejandra
Acha Aranda2, Ana Ferrer Dufol3, Emilio Nevado Losada2.
1
ICU. Principe de Asturias Hospital, Alcalá de Henares, Spain; 2Intensive Care Unit. Principe deAsturias Hospital, Alcalá de Henares, Spain; 3Unit of Clinical Toxicology. Clinic University Hospital,
Zaragoza, Spain.

120

Continuous renal replacement therapy in poisoning
Katja M K Lundquist1, Lotte C G Høgberg2, Søren Bøgevig1.
1
Department of Clinical Pharmacology, Copenhagen University Hospital - Bispebjerg andFrederiksberg, Copenhagen, Denmark; 2Department of Anaesthesia and Intensive Care, Copenhagen
University Hospital - Bispebjerg and Frederiksberg, Copenhagen, Denmark.

121

Management of tetanus: an “off-topic” for a Poison Control Center?
Monica Carnovale1, Azzurra Schicchi2, Lucia Bernasconi1, Valentina Negrini1, Davide Lonati2, Valeria
M Petrolini2, Elena Mattiuzzo2, Francesca Crema3, Carlo A Locatelli2.
1
Pavia Poison Control Centre - National Toxicology Information Centre - Clinical and Experimental
Lab, Toxicology Unit, Istituti Clinici Scientifici Maugeri IRCCS, Pavia Institute. Postgraduate School of
Pharmacology and Clinical Toxicology, University of Pavia, Pavia, Italy; 2Pavia Poison Control Centre- National Toxicology Information Centre - Clinical and Experimental Lab, Toxicology Unit, Istituti
Clinici Scientifici Maugeri IRCCS, Pavia Institute, Pavia, Italy; 3Department of Internal Medicine andTherapeutics, Section of Pharmacology, University of Pavia, Pavia, Italy.

122

Bromoform ingestion causes gastrointestinal radioopacities, apparent hyperchloraemia andcarboxyhaemoglobinaemia
Darren M Roberts1, Mina Roberts2, Nazila Jamshidi1.
1
NSW Poisons Information Centre, Sydney Children’s Hospitals Network, Sydney, Australia;
2
Emergency Medicine, The Canberra Hospital, Canberra, Australia.

123

Sodium nitrite ingestions, mission impossible?
Erik Lindeman, Jasmin Khessib, Johanna Nordmark Grass.
Swedish Poisons Information Centre, Stockholm, Sweden.

124

A fatal case of iatrogenic iodine toxicity
Amanda G Holford, Katherine Z Isoardi.
Clinical Toxicology Unit, Princess Alexandra Hospital; Queensland Poisons Information Centre,
Brisbane, Australia.

MONITORING OF NEW PSYCHOACTIVE SUBSTANCES (NPS)125

Gamma-hydroxybutyrate (GHB) intoxication is associated with hypothermia: a case series of
790 patients with analytical confirmation of psychoactive substance exposure
Shaun Greene1, Zeff Koutsogiannis1, Sarah Hodgson1, Rebekka Syrjanen1, Rachelle Abouchedid1,
Jennifer Schumann2.
1
Victorian Poisons Information Centre, Melbourne, Australia; 2Victorian Institute of Forensic Medicine,
Melbourne, Australia.

126

Gamma-hydroxybutyrate intoxication is associated with bradycardia, but not blood pressure
derangement: A case series of 790 patients with comprehensive analytical confirmation of
psychoactive substance exposure
Shaun L Greene1, Rebekka Syrjanen1, Rachelle Abouchedid1, Sarah Hodgson1, Zeff Koutsogiannis1,
Jennifer Schumann2.
1
Victorian Poisons Information Centre, Melbourne, Australia; 2Victorian Institute of Forensic Medicine,
Melbourne, Australia.

40

127

Characterisation of illicit drug exposures within an early warning system: Medical record
documentation performs poorly compared to comprehensive toxicological analysis of biofluid
Rebekka Syrjanen1, Jennifer Schumann2, Sarah Hodgson1, Rachelle Abouchedid1, Zeff Koutsogiannis1,
Shaun Greene1.
1
Victorian Poisons Information Centre, Austin Health, Heidelberg, Victoria, Australia; 2Victorian
Institute of Forensic Medicine, Southbank, Victoria, Australia.

128

Diphenidine, methoxyphenidine and related 1,2-diarylethylamine acute toxicity reported to theEuro-DEN Plus projectDavid M Wood1, Alison M Dines2, Matthias E Liechti3, Isabelle Giraudon4, Fridtjof Heyerdahl5, Knut
Erik Hovda6, Odd Martin Vallersnes7, Oscar Miro8, Christopher Yates9, Euro-Den Plus ResearchGroup2, Paul I Dargan1.
1
Clinical Toxicology, Guy’s and St Thomas’ NHS Foundation Trust and Faculty of Life Sciences andMedicine, King’s College London, London, United Kingdom; 2Clinical Toxicology, Guy’s and St Thomas’
NHS Foundation Trust, London, United Kingdom; 3Division of Clinical Pharmacology and Toxicology,
University Hospital Basel and University of Basel, Basel, Switzerland; 4European Monitoring Centre forDrugs and Drug Addiction (EMCDDA), Lisbon, Portugal; 5Prehospital Division, Oslo University Hospitaland The Norwegian Air Ambulance Foundation, Oslo, Norway; 6The Norwegian CBRNE Centre of
Medicine, Oslo University Hospital, Oslo, Norway; 7Department of General Practice, Oslo University and
Oslo Accident and Emergency Outpatient Clinic, City of Oslo Health Agency, Oslo, Norway; 8Emergency
Department, Hospital Clínic, IDIBAPS, University of Barcelona, Barcelona, Spain; 9Emergency Department
and Clinical Toxicology Unit, Hospital Universitari Son Espases, Mallorca, Palma, Spain.

129

Characteristics of analytically confirmed novel opioid exposures in patients presenting toemergency departments within the state of Victoria, Australia
Shaun Greene1, Rachelle Abouchedid1, Sarah Hodgson1, Rebekka Syrjanen1, Jennifer Schumann2.
1
Victorian Poisons Information Centre, Melbourne, Australia; 2Victorian Institute of Forensic Medicine,
Melbourne, Australia.

130

Illicit substance use and physical restraint: A prospective cohort study of 1125 patients presenting
to Emergency Departments with analytically confirmed psychoactive substance exposure
Sarah E Hodgson1, Rachelle Abouchedid1, Rebekka Syrjanen2, Jennifer Schumann2, Shaun L Greene1.
1
Victorian Poisons Information Centre, Melbourne, Australia; 2Victorian Institute of Forensic Medicine,
Melbourne, Australia.

131

Counterfeit “Xanax®” tablets in Australia – more than you bargained for?
Rebekka Syrjanen1, Jennifer Schumann2, Sarah Hodgson1, Rachelle Abouchedid1, Shaun Greene1.
1
Victorian Poisons Information Centre, Austin Health, Heidelberg, Victoria, Australia; 2The Victorian
Institute of Forensic Medicine, Southbank, Victoria, Australia.

132

Over half of fatalities in 1123 patients presenting to emergency departments with analyticallyconfirmed exposure to a psychoactive substance are associated with heroin use
Rachelle Abouchedid1, Sarah Hodgson1, Rebekka Syrjanen1, Jennifer Schumann2, Shaun Greene1.
1
Victorian Poisons Information Centre, Austin Health, Melbourne, Australia; 2Drug Intelligence Unit,
Victorian Institute of Forensic Medicine, Monash University, Melbourne, Australia.

133

Trends in detections of unregistered benzodiazepines and counterfeit alprazolam in New South
Wales, Australia
Jared A Brown1, Tracy Ho1, Thanjira Jiranantakan1, Una Cullinan2, Nicole Wright3, Christopher Ewers2,
Darren Roberts3, Marissa Parry1.
1
NSW Ministry of Health, Sydney, Australia; 2NSW Health Pathology, Sydney, Australia; 3NSW Poisons
Information Centre, Sydney, Australia.

134

Are novel psychoactive substances (NPS) that share structural motifs with approved compounds
more likely to have a psychoactive effect?
Michael Chary.
Weill Cornell Medicine, New York, United States.

135

Rapid normalization of homocysteine after cessation of nitrous oxide exposure: a case series
Erik Lindeman, Ingi Abdulhameed, Johanna Nordmark Grass.
Swedish Poisons Information Centre, Stockholm, Sweden.

41

NEW ANTIDOTES (INCLUDING USE OF OLD ANTIDOTES FOR NEW PURPOSES)136

Expansion of the Dutch National Calamity Stock with infrequently used (non)-registeredantidotes is a great successMarieke A Dijkman, Dylan W De Lange.
Dutch Poisons Information Center, Utrecht, Netherlands.

137

A survey of antidote availability in Irish hospitals with emergency departments 2022
Conor T Hurley, Edel Duggan, John X Herbert.
National Poisons Information Centre (NPIC), Dublin, Republic of Ireland.

138

Carbapenems in valproate toxicity - ready for prime time?
Daniel HP Towie1, Erik Lindeman2.
1
Department of Internal Medicine. Skåne University Hospita, Lund, Sweden; 2Swedish Poisons
Information Centre, Stockholm, Sweden.

139

Antidotal effect of olanzapine in serotonin toxicity caused by a suicidal
3,4-methylenedioxymethamphetamine (MDMA) overdose
Erik Lindeman1, Linn Ottosson2, Anders Helander3.
1
Swedish Poisons Information Centre, Stockholm, Sweden; 2Department of Anaesthesiology andIntensive Care, Skaraborg Hospital, Skövde, Sweden; 3Department of Laboratory Medicine, Karolinska
Institutet and Karolinska University Laboratory, Stockholm, Sweden.

140

Heat stroke associated with 3,4-methylenedioxymethamphetamine (MDMA) overdose treatedwith olanzapine
Erik Lindeman1, Maria Daveus2, Eva Backman1.
1
Swedish Poisons Information Centre, Stockholm, Sweden; 2Department of Internal Medicine,
Kristianstad Central Hospital, Kristianstad, Sweden.

141

First report of successful treatment of severe serotonin toxicity with levomepromazine
Brenda H Van Koningsveld-Couperus1, Fellery De Lange1, Carina Bethlehem2.
1
Department of Intensive Care Medicine, Medical Centre Leeuwarden, Leeuwarden, Netherlands;
2
Department of Intensive Care Medicine and Department of Clinical Pharmacy and Pharmacology,
Medical Centre Leeuwarden, Leeuwarden, Netherlands.

142

Primaquine-induced methemoglobinemia treated with N-acetylcysteine: a case report
Lorenzo Losso1, Francesco Gambassi2, Brunella Occupati2, Alessandra Pistellli2, Andrea Missanelli2,
Cecilia Lanzi2, Arianna Totti2, Guido Mannaioni1, Alessandra Ieri2.
1
Department of Neurosciences, Psychology, Drug Research and Child Health, Section of Pharmacology
and Toxicology, University of Florence, Florence, Italy; 2Medical Toxicology Unit and Poison Control
Centre, Careggi University Hospital, Florence, Italy.

POISONS CENTRE ACTIVITIES
143

Retrospective evaluation of the effect of oral acetylcysteine on INR in the setting of acetaminophen
overdose
Varun Vohra1, Alisar Aljundi2, Hala Tokko2, Ryan Herc2, Jewel Konja2, Ali Khanafer2, Samantha Bauer3,
Victoria Tutag-Lehr2.
1Michigan Poison & Drug Information Center, Wayne State University School of Medicine, Detroit,
United States; 2Wayne State University Eugene Applebaum College of Pharmacy and Health
Sciences, Detroit, United States; 3Biostatistics, Epidemiology, and Statistical Design (BERD), Wayne
State University, Detroit, United States.

144

High-dose vitamin D supplements – a high risk?
Chantal CJ Roelen, Antoinette JHP Van Riel, Pauline M Verputten, Dylan W De Lange.
University Medical Center Utrecht, Utrecht, Netherlands.

42

145

Nirmatrelvir and ritonavir exposure and information cases reported to a single statewide UnitedStates poison center
Erin E Ryan, Ladonna A Gaines, Ann P Slattery.
Alabama Poison Information Center, Children’s of Alabama, Birmingham, Alabama, United States.

146

Wintergreen oil toxicity reported to the UK National Poisons Information Service (NPIS)
Emma Moyns1, Hayley Williams1, Euan A Sandilands2, Laurence A Gray3, Ruben HK Thanacoody4,
Sally M Bradberry1.
1
National Poisons Information Service (Birmingham Unit), Birmingham, United Kingdom; 2National
Poisons Information Service (Edinburgh Unit), Edinburgh, United Kingdom; 3National Poisons
Information Service (Cardiff Unit), Cardiff, United Kingdom; 4National Poisons Information Service(Newcastle Unit), Newcastle, United Kingdom.

147

Substantial room for improvement in handling medicines in Danish residential institutions
Karen R Eriksen, Nete B Hansen.
The Danish Poison Information Center, Dept. of Anaesthesia and Intensive Care Medicine, Bispebjergand Frederiksberg University Hospital of Copenhagen, Copenhagen, Denmark.

148

Collaboration between a poisons information centre and a national authority to protect
consumer safety
Patricia Casey1, Edel Duggan1, Sinead Mcmickan2.
1
National Poisons Information Centre of Ireland, Dublin, Republic of Ireland; 2Health and Safety
Authority, Athlone, Republic of Ireland.

149

Repeated poisonings in Denmark: a nationwide study
Thomas Leth Jensen1, Kim Peder Dalhoff2, Mathilde Tejlbo Frost2, Tonny Studsgaard Petersen2.
1
Departmen of Clinical Pharmacology, Bispebjerg and Frederiksberg Hospital, Capital Regionof Denmark, Copenhagen, Denmark; 2Bispebjerg and Frederiksberg Hospital, Capital Region of
Denmark, Copenhagen, Denmark.

150

A review of general information requests to the Finnish Poison Information Centre (FPIC)
Terhi Lampinen.
Poison Information Centre, Department of Emergency Medicine and Services, Helsinki University
Hospital and University of Helsinki, Helsinki, Finland.

151

Ethnic diversity of patients discussed with the UK National Poisons Information Service(Birmingham Unit): a short term pilot study
Pardeep S Jagpal, Hayley A Williams, Sally M Bradberry.
National Poisons Information Service, Birmingham, United Kingdom.

152

Potentially inappropriate medication in the elderly: data from a poison centre
Uwe Stedtler1, Undine Burmeister2, Johannes Nadler1, Maren Hermanns-Clausen3.
1
Poisons Information Center, Department of General Pediatrics, Adolescent Medicine andNeonatology, Center for Pediatrics, Medical Center - University of Freiburg, Freiburg, Germany;
2
Universitätsinstitut für Medizinische Mikrobiologie und Virologie, Universitätsmedizin, Oldenburg,
Germany; 3Poisons Information Center, Department of General Pediatrics, Adolescent Medicine andNeonatology, Center for Pediatrics, Medical Center - University of Freiburg, Freiburg, Germany.

153

A 10-year retrospective analysis of therapeutic errors involving prednisolone reported to the
UK’s National Poisons Information Service
Talan A Parnell1, Sally M Bradberry2, Euan A Sandilands3, Ruben HK Thanacoody4, Laurence A Gray1.
1
National Poisons Information Service, Cardiff, United Kingdom; 2National Poisons Information
Service, Birmingham, United Kingdom; 3National Poisons Information Service, Edinburgh, United
Kingdom; 4National Poisons Information Service, Newcastle, United Kingdom.

154

Retrospective study of serotonin syndrome enquiries to UK National Poisons Information Service
in 2021
Arran Mckinty1, Sally M Bradberry2, Euan A Sandilands3, Ruben HK Thanacoody4, Laurence A Gray1,
James M Coulson1.
1
National Poisons Information Service, Cardiff, United Kingdom; 2National Poisons Information
Service, Birmingham, United Kingdom; 3National Poisons Information Service, Edinburgh, United
Kingdom; 4National Poisons Information Service, Newcastle, United Kingdom.

43

155

A case of laboratory confirmed diphtheria: migratory flows, infectious diseases and the role ofPoison Control Centres (PCC)
Giulia Scaravaggi, Davide Lonati, Azzurra Schicchi, Valeria M Petrolini, Lucia Bernasconi, Monica
Carnovale, Carlo A Locatelli.
Pavia Poison Control Centre - National Toxicology Information Centre - Clinical and Experimental
Lab, Toxicology Unit, Istituti Clinici Scientifici Maugeri IRCCS, Pavia Institute, Pavia, Italy.

156

Involuntarily drugging: increasing numbers of inquiries about suspected drink spiking reported
to the Danish Poison Information Center
Dorte F Palmqvist, Lisbeth Bringgaard.
The Danish Poison Information Center; Department of Anaesthesia and Intensive Care, Bispebjerg –and Frederiksberg University Hospital of Copenhagen, Copenhagen, Denmark.

157

How can we help you? Collaboration between Poisons Information Centre and ambulanceservices in Estonia
Ruth Kastanje, Mare Oder.
Estonian Health Board, Tallinn, Estonia.

158

Patterns of fentanyl exposures reported to the U.S. Poison Centers
Saumitra Rege, Ryan Cole, Christopher Holstege.
The University of Virginia, Charlottesville, United States.

159

Trends in calls to the National Poisons Information Centre of Ireland following the introduction ofa phone number for the general public
Niamh English1, Patricia Casey2.
1
National Poisons information Centre, Dublin, Republic of Ireland; 2National Poisons Information
Centre, Dublin, Republic of Ireland.

160

Comparison of poisoning patterns during COVID-19 pandemic with the trend analysis-predicted
modelsZanina Pereska, Niko Bekjarovski, Natasha Simonovska, Aleksandra Babulovska, Afrodita BeratHusein, Kiril Naumoski, Kristin Kostadinoski.
University Clinic of Toxicology, Ss Cyril and Methodius University, Skopje, Macedonia.

TOXIC EFFECTS AT THERAPEUTIC DOSES /ADVERSE REACTIONS FROMMEDICATIONS
161

SARS-CoV-2 infection is not predictive for renal function impairment after non-steroidal antiinflammatory drug use – a case-control study
Aurélie Pahud De Mortanges1, Verena Schöning2, Evangelia Liakoni2, Felix Hammann2.
1
Clinical Pharmacology and Toxicology, Department of General Internal Medicine, Inselspital, Bern
University Hospital and Graduate School for Health Sciences, University of Bern, Bern, Switzerland;2
Clinical Pharmacology and Toxicology, Department of General Internal Medicine, Inselspital, Bern
University Hospital, University of Bern, Bern, Switzerland.

162

Accidental subcutaneous injection of isopropyl alcohol to hallux during digital block resulting in
necrosisShireen Banerji, Christopher Pitotti.
Rocky Mountain Poison Center, Denver, United States.

163

Prolonged effect of chlordiazepoxide more than a month after intake, requiring treatment withflumazenil
Nanna Reiter1, Christian A Wamberg1, Kim P Dalhoff2, Tonny S Petersen2.
1
aDepartment of Anaesthesiology and Intensive Care, Bispebjerg and Frederiksberg Hospital,
Copenhagen, Denmark; 2bDepartment of Clinical Pharmacology, Bispebjerg and Frederiksberg
Hospital, Copenhagen, Denmark.

164

Myeloneuropathy in a patient receiving treatment with Entonox© for recurrent shoulder
dislocations: acase report
Gurpreet S Jutley, Rehman Crisp, Mark Pucci.
University Hospitals Birmingham NHS Foundation Trust, Birmingham, United Kingdom.

44

165

Adverse reactions of oral methylprednisolone therapy in children with Multisystem Inflammatory
Syndrome associated with COVID-19
Viorela Nitescu1, Diana Usurelu2, Ana-Maria Mihalcea2, Teodora Turcu2, Andra Postelnicu2, Ruxandra
Stejeroiu2, Stefania Ionescu2, Dorina Craciun3, Coriolan Ulmeanu1.
1
Pediatric Poisoning Centre, “Grigore Alexandrescu “ Hospital, Bucharest, University of Medicine andPharmacy “Carol Davila”, Bucharest, Romania; 2Pediatric Poisoning Centre , “Grigore Alexandrescu“ Hospital, Bucharest, Romania; 3University of Medicine and Pharmacy “Carol Davila”, Bucharest,
Romania.

166

Stuck: Challenges in the Management of Clozapine-Induced Gastrointestinal Hypomotility(CIGH)
Joshua Bloom1, Mark L Abroms2, Mark K Su3.
1
Ronald O. Perelman Department of Emergency Medicine, NYU Grossman School of Medicine, New
York, NY, United States; 2Department of Psychiatry, NYU Grossman School of Medicine, New York,NY, United States; 3New York City Poison Control Center, Department of Health and Mental Hygiene,
New York, NY, United States.

167

Serotonin toxicity secondary to drug interactions involving selegiline, 5-hydroxytryptophan,carbidopa/levodopa, and tetrahydrobiopterin in a patient with dopa-responsive dystonia
Brian G Wiener1, Sarah G Mahonski2, Mary Ann Howland3, Mark K Su4, Robert S Hoffman1.
1
Division of Medical Toxicology, Ronald O. Perelman Department of Emergency Medicine, New York
University Grossman School of Medicine, New York, United States; 2Department of Emergency
Medicine, SUNY Upstate Medical University, Syracuse, United States; 3College of Pharmacy and
Health Sciences, St. John’s University, Queens, United States; 4New York City Poison Control Center,
New York, United States.

169

Spontaneous opioid detoxification: report of two cases
Norbertas Pašukonis1, Gabija Valauskaitė2, Robertas Badaras3.
1
Faculty of Medicine, Vilnius University, Vilnius, Lithuania; 2Department of Intensive Care Medicine,
Lithuanian University of Health Sciences, Kaunas, Lithuania; 3Toxicology Centre of Republic Vilnius
University Hospital, Vilnius, Lithuania.

170

QT prolongation and Torsade de Pointes in a 13-year-old transgender adolescent in treatment
with bicalutamide and tacrolimus
Ferran Gómez-Aguilar1, Lidia Martínez-Sánchez1, Vanessa Arias-Constantí1, David Muñoz-Santanach1,
Georgia Sarquella-Brugada2.
1
Pediatric Emergency Department. SJD Barcelona Children’s Hospital, Esplugues de Llobregat,
Spain; 2Cardiology Department. SJD Barcelona Children’s Hospital, Esplugues de Llobregat, Spain.

171

Hiccough like symptoms, global amnesia, confusion and neuro-motor denervation after
inadvertent subarachnoid injection of high dose clindamycin: a case report
Andrea Giampreti1, Marco Cirronis1, Mariapina Gallo1, Georgios Eleftheriou1, Raffaella Butera2, Lorella
Faraoni1, Maria Gioia Contessa1, Elisa Seghelini3, Giuseppe Bacis1.
1
Poison Control Center, ASST Papa Giovanni XXIII, Bergamo, Bergamo, Italy; 2Poison Control Center,
ASST Papa Giovanni XXIII, Bergamo, Brgamo, Italy; 3Institute of Anesthesia, Intensive Care andEmergency Medicine University of Brescia, Brescia, Italy.

172

Diffuse alveolar hemorrhage as an adverse effect of ticagrelor after percutaneous coronary
intervention
Rixt E Smit1, Fellery De Lange1, Steef J Sinkeler2, Annette L Van Ojik3, Carina Bethlehem4.
1
Department of Intensive Care Medicine, Medical Centre Leeuwarden, Leeuwarden, Netherlands;
2
Department of Cardiology, Medical Centre Leeuwarden, Leeuwarden, Netherlands; 3Departmentof Clinical pharmacy and pharmacology, Medical Centre Leeuwarden, Leeuwarden, Netherlands;
4
Department of Intensive Care Medicine and Department of Clinical pharmacy and pharmacology,
Medical Center Leeuwarden, Leeuwarden, Netherlands.

173

A new challenge in the toxicology department: euglycemic diabetic ketoacidosisÁgnes Bakos, Ildikó Urbán, István Elek.
Péterfy Sándor Hospital, Budapest, Hungary.

45

Posters 26th May 2023
EPIDEMIOLOGY OF POISONING
018

2, 4-Dinitrophenol use as discussed on social media
Ali Abdelati1, Stefan Bartell2, Michael Chary2.
1
Weill Cornell Medicine-Qatar, Doha, Qatar; 2Weill Cornell Medicine, New York, United States.

024

How does rhetorical stance affect the content of online discussions about DNP use?
Stefan Bartell, Michael Chary.
Weill Cornell Medicine, New York, United States

030

Shortages of medications for alcohol withdrawal treatment in the US and Europe: a five year
analysis
Christopher J Counts, Jennifer S Love.
Mount Sinai Hospital Department of Emergency Medicine, New York City, United States.

ANALYTICAL AND FORENSIC TOXICOLOGY - INCLUDING BEDSIDE TESTING
182

Untargeted liquid chromatography-mass spectrometry (LC-MS) to identify toxic exposures
can reduce unnecessary testing: a case of guanfacine poisoning
David H Schaffer, Abigail Kerns, Lindsay A Bazydlo, Christopher Holstege.
University of Virginia, Charlottesville, VA, United States.

183

Ketamine intoxication mimicking catatonia
Abigail Kerns, Lindsay Bazydlo, Christopher Holstege.
University of Virginia, Charlottesville, United States.

CORROSIVES AND CAUSTICS
184

Influence of age on clinical outcome following corrosive ingestion in adults
Blanka Caganova1, Silvia Plackova1, Erik Puchon1, Igor Batora2.
1
National Toxicological Information Centre, University Hospital Bratislava, Bratislava, Slovakia;
2
Department of occupational medicine and toxicology, Faculty of medicine Commenius University
Bratislava, Bratislava, Slovakia.

185

Caustic accidents due to ingestion of industrial products in public places: a case series
Valentina Negrini1, Cristina Grazioli1, Davide Lonati2, Benedetta Brolli1, Lucia Bernasconi1, Azzurra
Schicchi2, Valeria M Petrolini2, Olha Maystrova2, Francesca Crema3, Carlo A Locatelli2.
1
Pavia Poison Control Centre - National Toxicology Information Centre - Clinical and Experimental
Lab, Toxicology Unit, Istituti Clinici Scientifici Maugeri IRCCS. Postgraduate School of Pharmacology
and Clinical Toxicology, University of Pavia, Pavia, Italy; 2Pavia Poison Control Centre - National
Toxicology Information Centre - Clinical and Experimental Lab, Toxicology Unit, Istituti Clinici
Scientifici Maugeri IRCCS, Pavia, Italy; 3Department of Internal Medicine and Therapeutics, Sectionof Pharmacology, University of Pavia, Pavia, Italy.

HOUSEHOLD PRODUCTS POISONING
186

Biological features of laundry detergent capsules poisoning in children: a 7 year study
Viorela Nitescu1, Andreea Lescaie2, Ioana Alexandra Ilisei2, Alexandru Ulmeanu1, Coriolan Ulmeanu1.
1
Pediatric Poisoning Centre, Bucharest, University of Medicine and Pharmacy “Carol Davila”.
Bucharest, Romania; 2Pediatric Poisoning Centre, Bucharest, Romania.

46

187

Fatal methanol poisoning: case report
Julia V Radenkova-Saeva1, Dijana Angelov2.
1
Toxicology Clinic, University Hospital for Emergency Medicine “NI Pirogov”, Sofia, Bulgaria; 2Clinicof Toxicology, University Hospital for Emergency Medicine „ N.I.Pirogov”, Sofia, Bulgaria.

188

An unexpected case of fatal detergent ingestion
Amy Thomson, Rachel Khoury-Harb, Genevieve Adamo.
NSW Poisons Information Centre, Sydney, Australia.

189

Household hazard due to hygiene products – a whole new form of “nappy rash”
Mandy Gollmann1, Anja Michel2, Anne Stürzebecher1.
1
Poison Information Centre Erfurt, Erfurt, Germany; 2Poison Information Centre Freiburg, Freiburg,
Germany.

190

Disinfectant ingestion – a real danger in children
Viorela Nitescu1, Andreea Lescaie2, Dora Boghitoiu1, Coriolan Ulmeanu1.
1
Pediatric Poisoning Centre, Bucharest, University of Medicine and Pharmacy “Carol Davila”,
Bucharest, Bucharest, Romania; 2Pediatric Poisoning Centre, Bucharest, Romania.

MECHANISMS OF TOXICITY / BASIC RESEARCH
191

Risk/benefit ratios of a new opioid peptide, its nociceptin-linked hybrid and their sustainedrelease hydrogel-based formulations: an experimental study in mice
Clara Bicanhi1, Lucie Chevillard1, Charlotte Martin2, Steven Ballet2, Bruno Mégarbane1.
1
INSERM UMRS-1144, Paris Cité University, Paris, France; 2Research Group of Organic Chemistry, Vrije
Universiteit Brussel, Brussels, France.

METAL POISONINGS
192

Lead poisoning in a family - plastic manufacturing or herbal powder?
Dong-Zong Hung.
Division of Toxicology, China Medical University Hospital, Taichung City, Taiwan.

193

The effect of mercury on children
Olga Otrubova1, Silvia Plackova2, Blanka Caganova2, Erik Puchon2, Igor Batora3.
1
National Toxicological Information Centre, Department of Occupational Medicine and Toxicology,
Faculty of Medicine, Comenius University, Bratislava, Slovakia; 2National Toxicological Information
Centre, Department of Occupational Medicine and Toxicology, University Hospital Bratislava,
Bratislava, Slovakia; 3Department of Occupational Medicine and Toxicology, Faculty of Medicine,
Comenius University, University Hospital Bratislava, Bratislava, Slovakia.

194

Barium chloride poisoning
Kai-Ju Lee1, Jou-Fang Deng1, Daniel Spyker2.
1
National Poison Center, Taipei Veterans General Hospital, Taiwan, Taipei City, Taiwan; 2Emergency
Medicine, Oregon Health & Science University, Portland, OR, United States.

195

Lead encephalopathy with fatal outcome in pediatric patients: a case series
Cinthia D Gigliotti, Ana P Voitzuk, Vanina Greco.
National Poison Center (CNI), Profesor Alejandro Posadas National Hospita,, Buenos Aires, Argentina.

196

Acute lead poisoning from drinking tea with “lead-sugar”
Erik Lindeman1, Per Leanderson2.
1
Swedish Poisons Information Centre, Stockholm, Sweden; 2Occupational and Environmental
Medicine Center in Linköping, and Department of Health, Medicine and Caring Sciences, Linköping
University, Linköping, Sweden.

47

ORGAN TRANSPLANTATION FROM INTOXICATED DONORS
197

Successful organ transplantation after fatal yew ingestion
Anne Stuerzebecher1, Michael Deters1, Monika Scholle2, Svitlana Ziganshyna3.
1
Poisons Information Centre Erfurt, Erfurt, Germany; 2Deutsche Stiftung Organtransplantation,
Leipzig, Germany; 3University of Leipzig Medical Center, Leipzig, Germany.

PAEDIATRIC POISONING
198

Paediatric exposure to concentrated clorofene solutions
Jonas Moens, Heleen Van Melckebeke, Jonas Van Baelen, Lieve Stammen †, Karolien De Leneer,
Dominique Vandijck, Anne-Marie Descamps.
Antigifcentrum, Neder-Over-Heembeek, Belgium.

199

Fatal pediatric colchicine overdose: role for early initiation of granulocyte colony stimulating
factor?
Courtney Granter1, Caitlin E Wolfe2, Jill Duncan2, Marnie J Wood3, Nancy Murphy2.
1
IWK Pharmacy Department, Halifax, Canada; 2Atlantic Canada Poison Centre, Halifax, Canada; 3Nova
Scotia Medical Examiner Service, Dartmouth, Canada.

200

Fatal poisoning in childhood in England and Wales, 2006-2020
Mark Anderson.
National Poisons Information Service (UK), Newcastle upon Tyne, United Kingdom.

202

Relationship of suicide attempts with reopening of schools after their long-term closure due to
COVID-19
Katerina Kotikova1, Daniela Pelclova1, Tomas Navratil2.
1
Toxicological Information Centre, Department of Occupational Medicine, Charles University, andGeneral University Hospital, Prague, Czech Republic; 2Department of Electrochemistry at the
Nanoscale, J. Heyrovsky Institute of Physical Chemistry of the Czech Academy of Sciences, Prague,
Czech Republic.

203

Dimetindene – too strict toxic dose?
Michal Cecrle1, Daniela Pelclova2.
11) Toxicological Information Centre, Department of Occupational Medicine, General University
Hospital in Prague, 2) Institute of Pharmacology, First Medical Faculty of the Charles University,
Prague, Czech Republic; 2Toxicological Information Centre, Department of Occupational Medicine,First Medical Faculty of the Charles University and General University Hospital in Prague, Prague,
Czech Republic.

204

Accidental poisoning at home in children aged 10 years and younger in the UK during the
COVID-19 pandemic
Eleri Thomas1, Stephen Jones1, Sally M Bradberry2, Euan A Sandilands3, Ruben HK Thanacoody4,
Laurence A Gray1.
1
National Poisons Information Service, Cardiff, United Kingdom; 2National Poisons Information
Service, Birmingham, United Kingdom; 3National Poisons Information Service, Edinburgh, United
Kingdom; 4National Poisons Information Service, Newcastle, United Kingdom.

205

Risk factors for deliberate self-poisoning among children and adolescents in the Netherlands: aprospective study
Ilze MJ Thoonen, Saskia J Rietjens, Irma S Van Den Hengel-Koot, Dylan W De Lange, Arjen Koppen.
Dutch Poisons Information Center UMC Utrecht, Utrecht, Netherlands.

206

Deaths in pediatric patients from suspected suicide attempts by self-poisoning
Will R Goodrich, Rita Farah, Nathan P Charlton.
Division of Medical Toxicology, Department of Emergency Medicine, University of Virginia Health,Charlottesville, United States.

48

207

Edible cannabis exposures in pediatric patients misdiagnosed as seizures leading to
unnecessary and costly medical testingWill R Goodrich1, Ryan J Cole1, Lindsay A. L. Bazydlo2, Christopher P Holstege1.
1Division of Medical Toxicology, Department of Emergency Medicine, University of Virginia Health,Charlottesville, United States; 2Department of Pathology, University of Virginia School of Medicine,Charlottesville, United States.

208

Voluntary intoxications in adolescents during the pandemic period
Arianna Festa1, Valeria M Petrolini1, Federico Fassio2, Lucia Bernasconi1, Benedetta Brolli1, Valentina
Negrini1, Cristina Grazioli1, Giulia Scaravaggi1, Carlo A Locatelli1.
1
Pavia Poison Control Centre - National Toxicology Information Centre - Clinical and Experimental
Lab, Toxicology Unit, Istituti Clinici Scientifici Maugeri IRCCS, Pavia Institute, Italy, Pavia, Italy;
2
Biostaistics and Clinical Epidemiology Unit-Department of Public Health, Experiemntal and Forensic
Medicine-University of Pavia, Pavia, Italy.

PHARMACEUTICAL POISONING
209

Increasing severity of propranolol poisoning in Edinburgh, UK
Emma E Morrison, Michal Klatka, Euan A Sandilands.
National Poisons Information Service, Edinburgh, United Kingdom.

210

Antimuscarinic toxicity presenting as a stroke mimicking hypertensive akinetic mutism withresponse to physostigmine
Brandtly Yakey1, Michael Gyory2, Erik Olsen2, Varun Vohra3, Andrew King3.
1
Michigan Poison & Drug Information Center - Wayne State University School of Medicine, Detroit,
United States; 2Detroit Medical Center, Detroit, United States; 3Michigan Poison & Drug Information
Center, Wayne State University School of Medicine, Detroit, United States.

211

Psychosis related to chronic prednisone overdose
Natanael Del Ángel González1, Yadira J Rosales Bacilio1, Jorge G Pérez Tuñón1, Sindy L Ortega
Martinez1, Arturo G Ponce De León1, Liz E Rodríguez Hernández2.
1
Centro Toxicológico Hospital Ángeles Lomas, Huixquilucan, Mexico; 2Instituto Mexicano del Seguro
Social, Ecatepec, Mexico.

213

Acute midodrine overdose
Byung Hak So.
Department of Emergency Medicine, St. Vincent’s Hospital, College of Medicine, The Catholic
University of Korea, Seoul, Korea, Suwon, South Korea.

214

Assessment of acute methylphenidate toxicity
Marianne J Petscher, Florian Eyer, Tobias Zellner.
Department of Clinical Toxicology, Technical University of Munich, Munich, Germany.

215

Same initial drug name and pharmacist dispensing errors: a case series
Anna A Celentano, Marcello M Ferruzzi, Fabrizio F Sesana, Francesco F Scaglione.
Milan Poison Control Center, ASST Grande Ospedale Metropolitano Niguarda, Milan, Italy.

216

Survival after severe bupropion toxicity treated with extracorporeal membrane oxygenation (ECMO)
Brian G Wiener1, Sage W Wiener2, Mary Ann Howland3, Mark K Su4, Emily Cohen1.
1Division of Medical Toxicology, Department of Emergency Medicine, New York University Grossman
School of Medicine, New York, United States; 2Department of Emergency Medicine, SUNY Downstate
Medical University, New York, United States; 3College of Pharmacy and Health Sciences, St. John’s
University, New York, United States; 4New York City Poison Control Center, New York, United States.

217

Vitamin-K antagonist toxicity from empagliflozin dispensing error
Zachary P Schmitz, Mark K Su, Robert S Hoffman.
New York City Poison Control Center, New York City, United States.

49

218

Acute toxicity profile of promazine in overdose: a consecutive case series
Evelyne L Jina Prüss, Colette Degrandi, Katrin Faber, Alexander Jetter.
National Poisons Centre, Tox Info Suisse, Associated Institute of the University of Zurich, Zurich,
Switzerland.

219

Are methotrexate plasma quantifications important in intoxications with low-dose methotrexate?
Alexander Jetter, Seraina Kägi, Colette Degrandi, Cornelia Reichert, Katrin Faber.
National Poisons Centre, Tox Info Suisse, Associated Institute of the University of Zurich, Zurich,
Switzerland.

220

Chronic doxepin toxicity from supratherapeutic dosing, drug interactions, andpharmacogenomic variability masquerading as pediatric epilepsy
James D Whitledge1, Christopher J Watson2, Michele M Burns1.
1
Harvard Medical Toxicology Fellowship, Boston Children’s Hospital, Boston, United States;2
Department of Emergency Medicine, Maine Medical Center, Portland, United States.

221

Delayed salicylate toxicity requiring urinary alkalinization after undetectable eight-hour serum
salicylate concentration
Chris Y Feng, James Whitledge, Michael Simpson, Andrew Troger, Michele E Burns.
Boston Children’s Hospital, Boston, United States.

222

Late ventricular fibrillation cardiac arrest in a case of bupropion overdose with status epilepticus
Joshua Bloom1, Nata Cisse2, Mary Ann Howland3, Donald Doukas2, Sage W Wiener4, Mark K Su5.
1
Ronald O. Perelman Department of Emergency Medicine, NYU Grossman School of Medicine, New
York, NY, United States; 2Department of Emergency Medicine, NYCH+H/Kings County, Brooklyn, NY,
United States; 3St. John’s University College of Pharmacy and Health Sciences, Queens, NY, UnitedStates; 4Department of Emergency Medicine, SUNY Downstate Health Sciences University, Brooklyn,
NY, United States; 5New York City Poison Control Center, Department of Health and Mental Hygiene,
New York, NY, United States.

223

Ifosfamide neurotoxicity treated with methylene blue complicated by serotonin toxicit
Ahmed Alsakha, Jeanna M Marraffa.
Department of Emergency Medicine, SUNY Upstate Medical University, Syracuse, NY, United States.

224

Argatroban overdose without bleeding complications
Marlis Gnirke, Silas W Smith, Robert S Hoffman.
Division of Medical Toxicology, Ronald O. Perelman Department of Emergency Medicine, NYU
Grossman School of Medicine, New York City, United States.

225

Accidental minoxidil overdose with hypotension effectively managed with noradrenaline,
rather than dopamine.
Bashir Chakar, Mark Salter, Darren M Roberts.
NSW Poisons Information Centre, Sydney, Australia.

226

Acute toxicity profile of Deanxit®: a consecutive case series of overdoses over 48 years
Katrin Faber1, Arsenije Stojkovic2, Cornelia Reichert1, Alexander Jetter3.
1
National Poisons Centre, Tox Info Suisse, Associated Institute of the University of Zurich, Zurich,
Switzerland; 2Faculty of Medicine, University of Bern, Bern, Switzerland; 3National Poisons Centre, Tox
Info Suisse, Associated Institute of the University of Zurich”;”Department of Clinical Pharmacology
and Toxicology, University Hospital of Zurich,, Zurich, Switzerland.

227

Two are better (worse) than one: dapagliflozin and metformin combination drug overdose
Ophir Lavon.
Carmel Medical Center, Haifa, Israel.

228

A case of large intravenous terbutaline overdose
Kyle D Pires1, Mark Su2, William Chiang1.
1
Division of Medical Toxicology, Ronald O. Perelman Department of Emergency Medicine, NYU
Grossman School of Medicine, New York, United States; 2New York City Poison Control Center, New
York, United States.

50

229

A case series of hydroxychloroquine poisoning in Australia
Betty Shuk Han Chan1, Katherine Z Isoardi2, Geoffrey K Isbister3, Angela L Chiew1.
1
Prince of Wales Hospital, Sydney, Australia; 2Princess Alexandra Hospital, Brisbane, Australia; 3Mater
Calvary Newcastle Hospital, Newcastle, Australia.

230

A case report of hydroxychloroquine poisoning
Betty Shuk Han Chan1, Nicholas A Buckley2.
1
Prince of Wales Hospital, Sydney, Australia; 2Sydney University, Sydney, Australia.

231

A case of severe serotonin syndrome
Ildikó Urbán1, Ágnes Szombath2.
1
Péterfy Sándor Hospital, Clinical Toxicology Department, Budapest, Hungary; 2Péterfy Sándor
Hospital, Intensive Care Unit, Budapest, Hungary.

232

Usefulness of intravenous lipid emulsion for the management of cardiac toxicity in acuteflecainide overdose
Gaspar Tuero1, Jesús González1, Nértor González1, Isabel Gomila2, Laura Sahuquillo3, Miguel A Elorza4,
Bernardino Barceló5.
1
Intensive Care Unit, Hospital Can Misses, Ibiza, Spain; 2Clinical Analysis Department, Hospital
Universitari Son Llàtzer; Health Research Institute of the Balearic Islands (IdISBa), Palma de Mallorca,
Spain; 3Clinical Analysis Department, Hospital Can Misses, Ibiza, Spain; 4Clinical Analysis Department,
Clinical Toxicology Unit, Hospital Universitari Son Espases; Health Research Institute of the Balearic
Islands (IdISBa)), Palma de Mallorca, Spain; 5Clinical Analysis Department, Clinical Toxicology Unit,
Hospital Universitari Son Espases; Health Research Institute of the Balearic Islands (IdISBa),, Palmade Mallorca, Spain.

233

Nothing is as it seems: Hypoglycaemia, serotonin syndrome and arrhythmic storm in a nondiabetic patient.
Lorenzo Socias1, María Ortega1, María Sala1, Isabel Gomila2, Miguel Servera2, Miguel Elorza3, Bernardino
Barceló3.
1
Intensive Care Unit, Hospital Universitari Son Llàtzer, Palma de Mallorca, Spain; 2Clinical Analysis
Department, Hospital Universitari Son Llàtzer; Health Research Institute of the Balearic Islands(IdISBa), Palma de Mallorca, Spain; 3Clinical Analysis Department, Clinical Toxicology Unit, Hospital
Universitari Son Espases; Health Research Institute of the Balearic Islands (IdISBa), Palma de
Mallorca, Spain.

234

Serotonin toxicity in a confirmed overdose of fluoxetine and lamotrigine
Brian G Wiener1, Silas W Smith1, Mary Ann Howland2, Rana Biary1, Mark K Su3.
1
Division of Medical Toxicology, Ronald O. Perelman Department of Emergency Medicine, NewYork University Grossman School of Medicine, New York, USA, New York, United States; 2Collegeof Pharmacy and Health Sciences, St. John’s University, Queens, USA, Queens, United States; 3New
York City Poison Control Center, New York, USA, New York, United States.

235

Fluoxetine toxicity in a neonate due to maternal exposure with apparent improvement on
cessation of breastfeedin
Nathaniel I Keymer1, Akshay Phakey2, Sally M Bradberry3, Euan A Sandilands4, Ruben HK
Thanacoody5, Laurence A Gray1.
1
National Poisons Information Service, Cardiff, United Kingdom; 2Royal Free London NHS Foundation
Trust, London, United Kingdom; 3National Poisons Information Service, Birmingham, United Kingdom;
4
National Poisons Information Service, Edinburgh, United Kingdom; 5National Poisons Information
Service, Newcastle, United Kingdom.

236

Relative toxicity of calcium channel blockers
Geoffrey K Isbister, Shane Jenkins, Michael A Downes.
Clinical Toxicology Research Group, University of Newcastle, Newcastle, Australia.

237

Accidental tetrahydrocannabinol ingestion in a child resulting in refractory hypotension
requiring vasopressor medication
Abigail Kerns, Christopher Holstege.
University of Virginia, Charlottesville, United States.

51

238

Accidental child exposure to a fentanyl patch: what is the lesson?
Gabija Valauskaite1, Dovydas Burkojus2, Robertas Badaras3, Andrius Macas4, Rimantas Kevalas5.
1
Department of Intensive Care Medicine, Lithuanian University of Health Sciences, Kaunas, Lithuania;
2
Department of Neurology, Lithuanian University of Health Sciences, Kaunas, Lithuania; 3Clinic ofAnaesthesiology and Intensive Care, Faculty of Medicine, Centre of Toxicology, Vilnius University,
Vilnius, Lithuania; 4Department of Anesthesiology, Lithuanian University of Health Sciences, Kaunas,
Lithuania; 5Department of Paediatrics, Lithuanian University of Health Sciences, Kaunas, Lithuania.

239

First series of massive paracetamol overdose cases: risk factors for hepatotoxicity
Isabel Gomila1, Jordi Puiguriguer2, Yolandada Ibáñez3, Guillermo Frontera4, Catalina Homar2,
Miguel Elorza5, Bernardino Barceló5.
1
Clinical Analysis Department, Hospital Universitari Son Llàtzer; Health Research Institute of the
Balearic Islands (IdISBa), Palma de Mallorca, Spain; 2Emergengy Department, Clinical Toxicology
Unit, Hospital Universitari Son Espases; Health Research Institute of the Balearic Islands (IdISBa),
Palma de Mallorca, Spain; 3Emergengy Department, Hospital Universitari Son Llàtzer, Palma de
Mallorca, Spain; 4Methodological Support Department of the Research Institute, Hospital Universitari
Son Espases, Palma de Mallorca, Spain; 5Clinical Analysis Department, Clinical Toxicology Unit,
Hospital Universitari Son Espases; Health Research Institute of the Balearic Islands (IdISBa), Palmade Mallorca, Spain.

240

Management of severe salicylate toxicity compromised by staff shortages
Ryan J Cole, Will R Goodrich, Aaron S Frey, Nathan P Charlton, Christopher P Holstege.
Division of Medical Toxicology, Department of Emergency Medicine, University of Virginia Health,Charlottesville, United States.

241

Self-induced pregabalin coma successfully resolved using continuous renal replacement
therapy
Lotte C G Høgberg1, Visti T Nielsen2, Søren Bøgevig3.
1
The Danish Poisons Information Centre; Department of Anaesthesia and Intensive Care, Copenhagen
University Hospital - Bispebjerg and Frederiksberg, Copenhagen, Denmark; 2Department of Anaesthesia
and Intensive Care, Copenhagen University Hospital - Bispebjerg and Frederiksberg, Copenhagen,Denmark; 3The Danish Poisons Information Centre; Department of Clinical Pharmacology, Copenhagen
University Hospital - Bispebjerg and Frederiksberg, Copenhagen, Denmark.

242

Clinical characteristics of acute lacosamide poisoning: a case series
Lucia Bernasconi1, Azzurra Schicchi2, Valeria M Petrolini3, Benedetta Brolli1, Monica Carnovale1,
Alberto Malovini4, Francesca Crema5, Carlo A Locatelli3.
1
Pavia Poison Control Centre - National Toxicology Information Centre - Clinical and Experimental Lab,
Toxicology Unit, Istituti Clinici Scientifici Maugeri IRCCS. Postgraduate School of Pharmacology andClinical Toxicology, University of Pavia, Pavia, Italy; 2Pavia Poison Control Centre - National Toxicology
Information Centre - Clinical and Experimental Lab, Toxicology Unit, Istituti Clinici Scientifici Maugeri
IRCCS, Pavia Institute. Experimental Medicine PhD Program, University of Pavia, Pavia, Italy; 3Pavia
Poison Control Centre - National Toxicology Information Centre - Clinical and Experimental Lab,
Toxicology Unit, Istituti Clinici Scientifici Maugeri IRCCS, Pavia Institute, Pavia, Italy; 4Laboratoryof Informatics and Systems Engineering for Clinical Research, Istituti Clinici Scientifici Maugeri
IRCCS, Pavia Institute, Pavia, Italy; 5Department of Internal Medicine and Therapeutics, Section of
Pharmacology, University of Pavia, Pavia, Italy.

243

Severe valproate intoxication with delayed toxicity because of pharmacobezoar formation within vitro verification
Miriam Mayor1, Thais Lizondo2, Emilio Salgado3, Silvia González2, Carmen López2, Carlos García1.
1
Hospital Clinic of Barcelona - Internal Medicine, Barcelona, Spain; 2Hospital Clinic of Barcelona- Hospital Pharmacy, Barcelona, Spain; 3Hospital Clinic de Barcelona - Toxicology Department,
Barcelona, Spain.

244

Outcome of acetaminophen-poisoned patients admitted to a non-liver intensive care unit withliver failure: an observational cohort study
Alice Vottero1, Bruno Mégarbane2.
1
Department of Medical and Toxicological Critical Care, Lariboisière Hospital, INSERM UMRS-1144,
Paris Cité University, Paris, France; 2Department of Medical and Toxicological Critical Care, INSERM
UMRS-1144, Paris Cité University, Paris, France.

52

245

The association between paracetamol dose/plasma concentration and the severity ofmethemoglobinemia: a case-control study
Tonny S Petersen1, Alaa Daoud1, Søren Bøgevig2, Lotte C G Høgberg3.
1
Department of Clinical Pharmacology, Copenhagen, Denmark; 2Department of Clinical pharmacology,
Copenhagen, Denmark; 3Department of Anaesthesia and Intensive Care, Copenhagen University
Hospital - Bispebjerg and Frederiksberg, Copenhagen, Denmark.

246

Brugada phenocopy after successful bicarbonate resuscitation in a patient with severe
amitriptyline overdose
Carlos García-Gutiérrez, Julia Calvo-Jiménez, Blanca Coll-Vinent Puig, Míriam Mayor EchaveSustaeta, Emilio Salgado-García.
Hospital Clínic i Provincial de Barcelona, Barcelona, Spain.

247

The SNAP Protocol: further benefits, further afield
Ruadhan O Laoi1, Cormac Kennedy1, Emer Kidney2, Arthur Hennessy3.
1
Department of Pharmacology and Therapeutics, St James’ Hospital, Dublin, Republic of Ireland;
2
Tallaght University Hospital, Dublin, Republic of Ireland; 3Emergency Department, St James’
Hospital, Dublin, Republic of Ireland.

248

Paediatric overdoses of melatonin: data from a national poison center
Karl Sebastian Johansson1, Lotte C G Høgberg2, Søren Bøgevig1.
1
Department of Clinical pharmacology, Copenhagen University Hospital - Bispebjerg andFrederiksberg, Copenhagen, Denmark; 2Department of Anaesthesia and Intensive Care, Copenhagen
University Hospital - Bispebjerg and Frederiksberg, Copenhagen, Denmark.

249

Acetaminophen/opioid combination in overdose: can opioid-related toxicity be observed
without acetaminophen poisoning?
Tayebaly William, Bruno Mégarbane.
Department of Medical and Toxiclogical Critical Care, Lariboisière Hospital, INSERM UMRS-1144,
Paris Cité University, Paris, France.

250

Indigestion: endoscopic removal and whole bowel irrigation in a patient with a pharmacobezoar
Elia Morando1, Camilla Vecli2, Giorgio Ricci1, Giovanni Mantelli1, Matilde Bacchion1, Ilaria Costantini1.
1
Poison Centre of Verona, Verona, Italy; 2Emergency department of Santa Maria del Carmine Hospital,
Rovereto, Italy.

TOXICITY IN SPECIFIC ORGANS
251

Low volume therapeutic plasma exchange with low dose steroid therapy as treatment of toxininduced acute liver failure: a case series
Varada Aravindan1, Indira Madhavan2, Rohith Sasidharan3, Ajmal NM4.
1
Assistant Professor, Thrissur, India; 2Professor, Kasaragod, India; 3Senior resident, Thrissur, India;
4
Junior resident, Thrissur, India.

252

Cocaine-associated chest pain risk factors: a single centre experience
Mark Jovanović1, Miran Brvar2.
1
Department of Cardiology, University Medical Centre Ljubljana, Ljubljana, Slovenia; 2Centre ofClinical Toxicology and Pharmacology, University Medical Centre Ljubljana and Centre for ClinicalPhysiology, Faculty of Medicine, University of Ljubljana, Ljubljana, Slovenia.

53

CONGRESS EXHIBITORSSUPPORTERS

54

European Association of Poisons Centres and Clinical Toxicologists

EAPCCT: Board, Committees & Working Groups (WG)
The Board (2022-2024)

Ana Ferrer Dufol(Spain)President

Pardeep Jagpal(U.K.)
Member, 1st term

Horst Thiermann(Germany)
Past President

Paul Dargan(U.K.)
President-electPiotr Maciej Kabata(Poland)Member, 2nd term

Gabija Laubner(Lithuania)
Member, 2nd term

Laura Hondebrink(The Netherlands)
General Secretary

Ophir Lavon(Israel)Member, 1st term

Scientific and Meetings Committee

Lotte Hoegberg(Denmark)
Chair

Organize the scientific program of theAnnual Congress and EAPCCT
symposia for other international
meetings

Davide Lonati(Italy)Treasurer

Emilio Salgado Garcia(Spain)Member, 1st termMark Zammit(Malta)Backup GS & Treasurer

Ruben Thanacoody(U.K.)
Member, 1st term

Anne-Marie Descamps(Belgium)
Member, 1st term

Nicola Bates
Alexander Campbell(U.K.)(U.K.)
Abstracts editor Congress Liaison & Support& minutes

Communication Committee

Improve visibility of the EAPCCT; keep
contact to members; provide a platform
for members to participate.

Katrin Faber(Switzerland)
Chair

Includes: Newsletter; Website;
Social Medialotte.hoegberg@regionh.dk

katrin.faber@toxinfo.ch

Fellows Committee

Nominations Committee

Allister Vale(U.K.)
Chair

allistervale@gmail.com

Organize the Fellows’ awards
and activities as the EAPCCT
webinars series. Considers
applications for fellowship ofthe EAPCCT

Poisons Centre Activities WG

Horst Thiermann(Germany)
Chair

Horst.Thiermann@gmx.de

Represents the interests of theEuropean PCCs at the EU-Commission in
the implementation of the new legal
Maren Hermanns- regulations on chemical products andClausencosmetics(Germany)Chairmaren.hermanns-clausen@uniklinik-freiburg.de

Constitution WG
Updates the EAPCCT
constitution
Mark Zammit(Malta)Chairmark.zammit@um.edu.mt

Join us and get active

Nominate ≥1 candidates for each of theBoard positions to be filled at the next
election after seeking nominations
from EAPCCT members

Education & Accreditation WG

Evaluates EAPCCTs possible role in:continuing education
additional qualifications
developing an accreditation
Maren HermannsClausensystem(Germany)Chairmaren.hermanns-clausen@uniklinik-freiburg.de

Agreement Taylor & Francis WG

Laura Hondebrink(The Netherlands)
Chairl.hondebrink@umcutrecht.nl

Optimizes the affiliation agreement
between the EAPCCT and the publisherof the journal Clinical Toxicology.
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European Association of Poisons Centres and Clinical Toxicologists

EAPCCT

Aim: Advancing knowledge and understanding of the prevention,

diagnosis and management of all forms of poisoning
Engage & unite professionals in all fields of clinical toxicology
Members’ benefits
Reduced fees:- Annual congress registration(membership fee = congress discount)- Open access publications in Clinical
Toxicology (Taylor & Francis)

Founded1964

Scientific Journal

Free access to:- The journal Clinical Toxicology- Educational material- Webinars- Website forum- Contact details of other members- Newsletter- Previous congress presentations- Professional Forum

EAPCCT
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professional, social
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Annual CongressWebinars by Experts

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