Form 1

2017 Report Form for Collaboration with
Research Center for Biomedical Engineering

Year/month/date2009

Number

20 /March/2018
date:

To Chairman, Board of Directors, Research Center for Biomedical Engineering

ApplicantAffiliation Beckman Laser Institute(BLI), University of California, Irvine
Title
Professor, Director of BLI
Name
Bruce Tromberg
Address
1002 Health Sciences Road Irvine, CA 92612, USA
Phone
Fax
E-mail+1-(949)824-8705
none
bjtrombe@uci.edu
Report Form for Collaboration Research

Research Theme

Research Area

Research Period（和） 血行動態・血流イメージング用小型マルチアパーチャカメラの開発（English） Compact multi-aperture camera for hemodynamics and blood flow imaging
1. Biomaterials
X2. Bioengineering
3. Functional molecules
4. Chemistry/Electrical Engineering/Mechanical Engineering/Materials Science

From:Date/month/Year
01/06/2017

To: Date/month/Year
31/ 03/2018

Applicant Organization
Name
Bruce Tromberg
Mohammad Torabzadeh
Ata Sharif
Jun Tanida

Collaboration Partners
Research Center

Department
Beckman Laser Institute, The University ofCalifornia, Irvine
Beckman Laser Institute, The University ofCalifornia, Irvine
Beckman Laser Institute, The University ofCalifornia, Irvine
Graduate School of Information Science andTechnology, Osaka University

intheTitle
Professor,Director of BLIDoctorcoursestudent
Project ScientistProfessor

RoleGeneralmanagement
Evaluationofcamera
Protocoldevelopment
Camera systemdesignKeiichiro Kagawa (Associate Professor, Research Institute of Electronics,Shizuoka University)

Research Results (Including Purpose, Results, Figures, etc.)
Purpose: In this project, a compact camera head that provides multi-spectral SFDI and laser speckle imaging(LSI), called SFLS-TOMBO, is developed. The TOMBO module has nine lenses, to each of which any opticalfilter can be attached.
Results: Fig. 1 shows a photograph of a prototype multi-spectral TOMBO with a fixed sinusoidal patternprojector. Fig. 2 shows an image acquisition and signal processing flow. In a preliminary experiment, an arm wascaptured by changing the phase of projected sinusoidal pattern at 3 steps. After image registration with thephase-only correlation method, the maps of absorption coefficient and reduced scattering coefficient wereretrieved as shown in Fig. 3. In summary, the whole flow of image capturing and signal processing has been
established.

Filter asignment

Projector

3×3-aperture TOMBO

730nm

650nm

520nm

450nm

785nm

450nm

970nm

920nm

850nm

Fig. 1
Compound-eye
imageACcomponentsµ′s mapsµ′s 1DCcomponents
DC1LUT

S9

Phase-shiftmethodµ′s 9Deox
y-Hbµa mapsMelaninWater

µa 1…

S1…

AC9…

Multi-spectralimages

OxyHb…

Cropping

…

AC1

µa 9

DC9Fig. 2.

Fitting

Lipid

Acquired images (DC)
670nm

740nm

850nm

770nm

910nm

970nm

µa map00.04

0.08 []

2.5 []µ′s map
01.25

Fig. 3.

List of Publications Related to the Collaboration Research

None

List of Presentations ( Conference, Meeting, etc)
1. K. Kagawa, T. Omura, M. Torabzadeh, R. Saager, A. Sharif, A. Durkin, B. Tromberg, and J. Tanida, “Compactcompound-eye camera with sinusoidal pattern projector for multi-spectral frequency domain imaging,” in Proc.
Optics and Photonics Japan (OPJ) 2017 (2017).
2. K. Kagawa, T. Omura, M. Torabzadeh, A. Sharif, A. Durkin, B. Tromberg, and J. Tanida, “A handy
compound-eye camera with sinusoidal pattern projector for multi-spectral spatial frequency domain tissueimaging,” in Proc. 2nd Int’l Symp. On Biomed. Eng. (2017).
List of AwardsNone

Research plan for the next year (from April 1, 2018 to March 31, 2019), if the collaboration research is continued.
Prior consent from the collaboration partner in the Research Center is necessary.
None