Symposium
S1 - Viral infection and immune responses
May 29th(Wed) 09:00-11:00, Room 101~102
Organizer & Chair

Eui-Cheol Shin (Korea Virus Research Institute)Chair

Ji Eun Oh (KAIST)

Speaker1

25' Hyunjoon Kim (Korea Virus Research Institute)

KLK5-Mediated Activations of Betacoronavirus Spike Proteins: Implications for a Therapeutic Target

Speaker2

25' Akinori Takaoka (Hokkaido University)

Novel sensing modes of action mediated by innate nucleic acid sensors for antiviral defense

Speaker3

20' Seon-Hui Hong (The Rockefeller University)

Mechanisms underlying attenuation of the yellow fever virus 17D vaccine strain

Speaker425' Ji Eun Oh (KAIST)B cell and antibody response against SARS-CoV-2 in solid cancer patients

Speaker525' Eui-Cheol Shin (Korea Virus Research Institute)

IL-15-induced bystander T cell activation in human viral disease

S2 - Ferroptosis: recent progress and new insights-KSMCB Joint Symposium
May 29th(Wed) 09:00-11:00, Room 106~107
Organizer & Chair

Cheol-Sang Hwang (Korea University), Sung Eun Kim (Korea University)

Chair

Eun-Woo Lee (Korea Research Institute of Bioscience & Biotechnology)

Speaker130' Michael Overholtzer (Memorial Sloan Kettering Cancer Center)

Speaker225' Hun-Taeg Chung (University of Ulsan)

Integrated Stress response and ferroptosis-mediated cell death

Speaker325' Cheol-Sang Hwang (Korea University)

The MARCHF6 E3 ubiquitin ligase is a critical regulator of ferroptosis

Speaker420' Namgyu Lee (Dankook University)

Selenium reduction of ubiquinone via SQOR suppresses ferroptosis

Speaker5

20' Yun Pyo Kang (Seoul National University)

Targeting lung cancer cysteine metabolism to accelerate ferroptosis

Spatiotemporal dynamics of ferroptosis

S3 - AI in Digital Biology
May 29th(Wed) 09:00-11:00, Room 201~202
Organizer

Jin-Wu Nam (Hanyang University)

Co-organizer & Chair

Jeong Hyobin (Yonsei University)

Speaker1

30' Minji Jeon (Korea University)

Transcriptome-based Drug Discovery using AI

Speaker2

30' David Ascher (The University of Queensland)

Predictive tools for personalised medicine and drug development

Speaker3

30' Dariusz Plewczyński (University of Warsaw)

Predicting chromatin interactions and gene expression by artificial intelligence methods and polymer biophysical simulations

Speaker4

30' Esa Pitkänen (University of Helsinki)

Deep representation learning for cancer medicine

S4 - Pioneering Mouse Model Studies for Metabolic and Endocrine Disorders
May 29th(Wed) 09:00-11:00, Room 203~204
Organizer

Je Kyung Seong (Seoul National University), Sungsoon Fang (Yonsei University), Yun-Hee Lee (Seoul National University)

Chair

Cheol Soo Choi (Gachon University), Jongsoon Lee (Soonchunhyang University)

Speaker1

35' Byung-Hyun Park (KAIST)

p21-activated kinase 4 counteracts PKA dependent lipolysis by phosphorylating FABP4 and HSL

Speaker2

35' Soo-Hyun Kim (St. George's University of London)

Kallmann syndrome-associated WDR11 regulates primordial germ cell development via canonical and noncanonical Hedgehog
signaling pathways

Speaker3

30' Hironori Waki (Akita University)

Epigenetic Regulation of Brown-Fat-Specific Genes by Nuclear Factor I-A and Its Role in Energy Homeostasis

Short talk

20' Kyunghee Lee (ProAbTech Ltd)In vivo study of newly developed albumin‑conjugated urate oxidase for gout treatment

S5 - Pluripotency, Differentiation and Reprogramming in Stem Cells
May 29th(Wed) 09:00-11:00, Room 205
Organizer & Chair

Hong-Duk Youn (Seoul National University), Ja-Lok Ku (Seoul National University)

Speaker1

25' Tae Wan Kim (DGIST)

Human pluripotent stem cell-based cell replacement therapy to Parkinson’s disease

Speaker225' Jinwook Choi (GIST)

Inflammatory Niche in stem cell plasticity and niche remodeling

Speaker325' Jang Hwan Kim (KRIBB)

The intermediate cells of reprogramming: potential applications in regenerative medicine

Speaker430' Kyung Min Noh (European Molecular Biology Laboratory)

Insights from studying chromatin regulators in stem cell models of neurodevelopment and disease

Speaker515' Han Teo Lee (Seoul National University)

Epigenetic regulation assisting preservation of pluripotency against DNA damage

S6 - T and B cell collaboration
May 29th(Wed) 15:40-17:40, Room 101~102
Organizer & Chair

Yeonseok Chung (Seoul National University)

Chair

Hye-Young Kim (Seoul National University)

Speaker1

30' Di Yu (The University of Queensland)

Regulation of humoral immunity and vaccine response by ferroptosis

Speaker2

30' You-Me Kim (KAIST)

Role of transcription factor EB in antibody responses

Speaker3

30' Youn Soo Choi (Seoul National University)

Transcriptional regulation of immune synapse and T-dependent humoral immunity

Speaker4

30' Hideki Ueno (Kyoto University)

The origin and features of human tonsil-resident memory CD4+ T cells

S7 - Recent Breakthrough in Osteobiology
May 29th(Wed) 15:40-17:40, Room 106~107
Organizer & Chair

Young Yang (Sookmyung Women's University)

Speaker1

25' Ji Hyeon Ju (The Catholic University of Korea)

Speaker2

25'Speaker3

25' Eun Young Lee (Seoul National University)

Exploring Multifaceted Aspects of Osteoclastogenesis in Chronic Inflammatory Arthritis

Speaker4

25' Michelle M McDonald (St. Vincent’s Clinical School)

Osteoclasts Recycle via Osteomorphs during RANKL-stimulated Bone Resorption

Kyung-Hyun Park-Min (Hospital for special surgery & Weill cornellmedicine)

Exploring bone biology using induced pluripotent stem cell
Origin of Osteoclasts

S8 - Membrane engineering toward protein secretion control
May 29th(Wed) 15:40-17:40, Room 201~202
Organizer & Chair

Joo-Yeon Yoo (POSTECH)

Speaker1

30' Tae-Young Yoon (Seoul National University)

Elucidation of membrane protein folding with single-molecule magnetic tweezers

Speaker2

30' Jae-Myung Suh (KAIST)

In vivo profiling of tissue-specific secretory proteins

Speaker3

30' Hyun (Joy) Kim (Seoul National University)

Substrate and cleavage site selection of the signal peptidase complex

Speaker430' Jia-Wei Hsu (National Taiwan University)

How to manage failed delivery: the discovery of coat adaptor in endocytic trafficking

S9 - New Advances and Multifaceted Aspects of Chemical Biology
May 29th(Wed) 15:40-17:40, Room 203~204
Organizer & Chair

Eun-Woo Lee (KRIBB), HoJeong Kwon (Yonsei University)

Speaker130' Christopher M. Overall (The University of British Columbia)

Development of Novel Molecular Correctors to Restore Impaired Enzymic and Scaffolding Functions in an Immunodeficient Patient
Identified by Positional Proteomics

Speaker230' Marcus Conrad (Helmholtz Zentrum München)

Modulating Ferroptosis for Disease Prevention

Speaker3

20' Hyun-Woo Rhee (Seoul National University)

Spray-type modifications: an emerging concept of PTM study

Speaker4

20' Donghyuk Shin (Yonsei University)

Recent Advances of Structure-Based Drug Discovery

Speaker5

20' Kyung S. Lee (National Institutes of Health)

From Peptides to Small Molecules: Targeting Polo-like Kinase 1 for Anticancer Therapy

S10 - Epigenetics and Chromatin Structure
May 29th(Wed) 15:40-17:40, Room 205
Organizer & Chair

TaeSoo Kim (Ewha Womans University)

Speaker1

20' Jinju Han (KAIST)

Nuclear AGO1 Shapes Brain Development and Social Behaviors

Speaker220' Jun-Yeong Lee (Kyungpook National University)

Unveiling the role of CpG islands in dual-mode gene regulation and its implications

Speaker320' Minhee Park (KAIST)To Build and Visualize Chromatin: Engineering Epigenome

Speaker430' Jun-An Chen (Academia Sinica)

Navigating the Nexus of Epigenetics and Epitranscriptomics in Aging and Neurodegeneration.

Speaker530' Michael-Christopher Keogh (Epicyper)

Nucleosome context dictates the histone code

S11 - Protein Structure & Design
May 30th(Thu) 09:00-11:00, Room 101~102
Organizer & ChairHo Min Kim (KAIST)

Speaker1

30' Justin Kollman (University of Washington)

Polymerization is a mechanism of enzyme regulation

Speaker230' Jae-Sung Woo (Korea University)

Lipid-mediated conformational equilibrium of gap junction intercellular channels

Speaker3

30' Jeong Min Chung (The Catholic University of Korea)

Unlocking the Secrets of Bacterial Infection: A Structural Study of Secretion Systems through Cryo-EM and Cryo-ET

Speaker4

30' Gyu Rie Lee (University of Washington)

The coming of age of atomic-level protein design: de novo design of small-molecule binding proteins using deep learning

S12 - Microbiome
May 30th(Thu) 09:00-11:00, Room 106~107
Organizer & Chair

Jin-Woo Bae (Kyung Hee University)

Speaker1

30' Kiyoshi Takeda (Osaka University)

Host-microbiota interaction for the maintenance of intestinal homeostasis

Speaker2

30' Soon-Kyeong Kwon (Gyeongsang National University)

Features of gut microbiome of responders to acupuncture treatment in patients with atopic dermatitis

Speaker3

30' Ara Koh (POSTECH)

Microbial metabolites in systemic circulation: Inter-kingdom messengers

Speaker4

30' Ye-Ji Bang (Seoul Nation University )Role of Intestinal Epithelium in Microbiota-Immune Interactions

S13 - Tumor Microenvironment
May 30th(Thu) 09:00-11:00, Room 201~202
Organizer & Chair

Sae-Ock Oh (Pusan National University)

Speaker1

35' Ninib Baryawno (Karolinska Institute)

The tumor microenvironment in the metastatic bone marrow niche

Speaker2

30' Sang-Jun Ha (Yonsei University)

Regulation of T cell immunity in tumor immune microenvironment

Speaker3

30' Hae-Ock Lee (The Catholic University of Korea)

Traversing from tumor cells to surroundings in the understanding of lung cancer

Speaker4

25' Dongjun Lee (Pusan National University)

Discovery of new regulators in hematopoietic stem cells and malignancies

S14 - Innovative Drug Developments
May 30th(Thu) 09:00-11:00, Room 203~204
Organizer & Chair

Sang Won Kang (Ewha Womans University)

Speaker1

30' Ji Yeon Kim (Yale University)

Bench to bedside, quality AND quantity of life: Cancer metabolism

Speaker2

20' Ssang-Goo Cho (Konkuk University)

Stem cell-derived extracellular vesicles with high regenerative and immunomodulatory abilities

Speaker3

30' Hyun Woo Park (Yonsei University)

Reprogramming anchorage plasticity of circulating tumor cells in metastasis

Speaker4

20' Chang Hoon Lee (KRICT)

Adenosine Metabolism as Exploitation for Therapeutic Target in Cancer

Speaker5

20' Weon-Kyoo You (ABL BIO)

Trends and strategies in the development of innovative antibody-based drugs: from discovery to clinical stage

S15 - Immune responses in the barrier and metabolic tissues
May 30th(Thu) 09:00-11:00, Room 205
Organizer & Chair

Min Jae Lee (Seoul National University)

Chair

Jin-A Lee (Hannam University)

Speaker1

23' Hyun Kyu Song (Korea University)

Expanding the structural repertoire of the N-degron pathway

Speaker2

23' Eun Joo Song (Ewha Womans University)

Regulation of Deubiquitinating Enzymes by Post-Translational Modifications

Speaker3

23' Myung-Shik Lee (Soonchunhyang University)

Development of autophagy/lysosomal enhancer for clearance of amyloid in vivo and treatment of diabetes & Alzheimer's disease

Speaker4

23' Hyun Jin Kim (Sungkyunkwan University)

Regulation of autophagy by the intracellular Ca2+ channel TRPML3

Speaker5

28' Shigeo Murata (University of Tokyo)

Dynamics and Role of Proteasomes in Cellular Senescence

S16 - Mechanisms of brain dysfunctions
May 31st(Fri) 13:00-15:00, Room 101~102
Organizer & Chair

Jaewhan Song (Yonsei University)

Chair

Jin Woo Kim (KAIST)

Speaker130' Naoko Ohtani (Osaka Metropolitan University)

The roles and mechanisms of cellular senescence and SASP in the tumor microenvironment of steatosis-associated liver cancer

Speaker230' Mei Tian (Fudan University)

Phenotypes and Multi-Omics Analysis of Aging: Unveiling the Secrets of Longevity and Health

Speaker325' Dongryeol Ryu (GIST)

Gut microbiota-generated metabolites and healthy aging

Speaker425' Chuna Kim (KRIBB)

Fibrotic Niche-enriched single-cell transcriptomics uncovers novel age-associated cell types

Speaker510' Seungyeon Kim (Yonsei University)

Suppression of MKRN1 E3 ligase function activates liver AMPK leading to prevention of nonalcoholic steatohepatitis

S17 - Physiological roles and application of GPCRs
May 31st(Fri) 13:00-15:00, Room 106~107
Organizer & Chair

JaeHyung Koo (DGIST)

Chair

Byungheon Lee (Kyungpook National University)

Speaker1

35' Seungkirl Ahn (Duke University)

A positive allosteric modulator of beta2-adrenergiv receptor – from isolation to structural and pathophysiological characterization

Speaker2

25' Youngmi Jung (Pusan National University)

Formyl peptide receptor 2 is an emerging regulator in the progression of liver disease

Speaker3

30' Hee-Jung Choi (Seoul National University)

Molecular mechanisms of odorant binding and activation in the human OR52 family

Speaker4

30' Hye Jin Kang (Yonsei University)

A Multiplexed GPCR Screening Platform that Sheds Light on New Biology

S18 - Extracellular matrix (ECM), fibrosis
May 31st(Fri) 13:00-15:00, Room 201~202
Organizer & Chair

Jung Weon Lee (Seoul National University)

Speaker1

25' Aree Moon (Duksung Women's University)

Roles of tumor microenvironment and autophagy in triple-negative breast cancer progression

Speaker225' Chungho Kim (Korea University)

Biologics approaches to regulate platelet function

Speaker3

25' Qing-jun Meng (University of Manchester)

Circadian regulation of extracellular matrix homeostasis in ageing and fibrosis

Speaker4

25' Katsuto Tamai (Osaka University)

Development of tissue regeneration-inducing medicine

Speaker5

20' Eun Hee Ahn (Hallym University)

Exploring Serum NTN4 and GAP-43 as Potential Biomarkers for Alzheimer's Disease Progression

S19 - Current New Development of CRISPR-Cas9 Technology
May 31st(Fri) 13:00-15:00, Room 203~204
Organizer & Chair

Kyungjae Myung (UNIST)

Speaker140' Michael Bassik (Stanford University)

Developing New Functional Genomics Tools to Investigate Tumor-Macrophage Interactions

Speaker2

25' Kayeong Lim (KIST)

Precise Genome Engineering: from Nucleus to Mitochondria

Speaker3

25' Yongsub Kim (University of Ulsan)

Precision genome engineering using CRISPR-mediated base and prime editors

Speaker4

25' Seung Woo Cho (UNIST)

Efficient induction of cancer-specific cell death using multiplexed CRISPR-Cas9 targeting cancer-specific mutations

S20 - Precision Medicine
May 31st(Fri) 13:00-15:00, Room 205
Organizer & Chair

Jong il Kim (Seoul National University)

Speaker140' Paul Valdmanis (University of Washington)

Association between population-specific tandem repeat expansions and human disease

Speaker2

30' Joon-Yong An (Korea University)

Identification of sex differences in autism using a large-scale whole genome sequencing analysis

Speaker3

30' Sun-Wha Im (Kangwon National University)

A whole-genome reference panel of 14,393 individuals for East Asian populations accelerates discovery of rare functional variants

Short talk10' Yunjin Go (Ajou University School of Medicine)

HepScope: A Prognostic Gene Set for Classifying Hepatocellular Carcinoma with Neural Networks and Immune LandscapeAnalysis

Short talk

10' Soyeon Kim (Sungkyunkwan University)

Mapping extrachromosomal DNA amplifications during cancer progression