ঢ়৴৾ভ૞ਸ੶The XVI European Biological Rhythms SocietyCongress (EBRS2019)प૞ਸखथ૝㭒 ᵷ୬叞৥੘প৾ ஗৾৖ ৿੟ে৶৾ଢ଼஢஼2019 ᖺ 8 ᭶ 25 ᪥࠿ࡽ 29 ᪥ࡲ࡛ࣇࣛࣥࢫ࣭ࣜࣚࣥࠕ㸦ࡶ࠺Ⓨ⾲࡞ࢇ࡚㸧࡛ࡁࡗࡇ࡞࠸ࡼ㸟ࡇࢇ࡞ࡢ஌ࢀ

ࡢ Faculté de Médecine Laennec ࡛㛤ദࡉࢀࡲࡋࡓ

ࡿࢃࡅ࡞࠸ࡼ㸟ࠖ࡜࠸࠺Ẽᣢࡕ࡛࠸ࡗࡥ࠸࡛ࡋࡓࡀࠊThe XVI European Biological Rhythms Societyࠕ㏨ࡆࡕࡷࢲ࣓ࡔࠖࢆ཯ⱄࡍࡿࡇ࡜࡛࡞ࢇ࡜࠿ᦚ஌࡛

Congress (EBRS2019) ࡟ཧຍࡋࡲࡋࡓࠋ157 ࡢཱྀ㢌ࡁࡲࡋࡓࠋึࡵ࡚ࡢᶵෆ㣗ࠊࣅ࣮ࣇ or ࢳ࡛࢟ࣥࡣࢤ₇㢟㸦ࣉࣞࢼ࣮ࣜࢆྵࡴ㸧࡜ 193 ࡢ࣏ࢫࢱ࣮₇㢟ࡀࣥᢸࡂ࡜ࡋ࡚㸦㸽㸧ࢳ࢟ࣥࢆ㑅ࡧࠊ⮑⑓࡞⮬ศࢆ႞ࡽ࠶ࡾࠊศᏊ࠿ࡽಶయࡲ࡛ከᵝ࡞᫬㛫⏕≀Ꮫⓗ࢔ࣉ࣮ࣟ࠸ᑾࡃࡑ࠺࡜ࡋࡲࡋࡓࠋ⌧ᆅ࡟฿╔ࡋࡓ᫬ࠊすྥࡁࡢࢳࢆຮᙉࡍࡿⰋ࠸ᶵ఍࡛ࡋࡓࠋ⚾⮬㌟ࠊᾏእ࡟⾜ࡃࡇ⛣ືࡔ࠿ࡽ࡞ࡢ࠿ࠊࡶ࡜ࡶ࡜఩┦ᚋ㏥ࡢ⏕ά࡟័ࢀ࡚࡜⮬యࡀ௒ᅇึࡵ࡚࡛ࠊࡉࡽ࡟࣮࢜ࣛࣝࣉࣞࢮࣥࢸ࣮࠸ࡿ࠿ࡽ࡞ࡢ࠿ࠊ᫬ᕪࡰࡅ࡟ࡼࡿయࡢ୙ㄪࢆឤࡌࡿࡇ

ࢩࣙࣥ࡟㑅ࢇ࡛࠸ࡓࡔࡃ࡜࠸࠺኱ኚ㈗㔜࡞⤒㦂ࢆࡉ࡜ࡣ඲ࡃ࠶ࡾࡲࡏࢇ࡛ࡋࡓࠋࡴࡋࢁ⌧ᆅ᫬㛫 6 ᫬ࡃࡽࡏ࡚ࡶࡽࡗࡓࡢ࡛ࠊᏛ఍“ཧຍグ”࡜࠸࠺ࡼࡾࡣᏛ఍

࠸࡟⮬↛࡟┠ࡀぬࡵࡿ࡜࠸࠺ࣉࣛࢫ㠃ࡀ࠶ࡾࡲࡋࡓࠋ

“య㦂グ”࡜ࡋ࡚ࡇࡇ࡟グࡑ࠺࡜ᛮ࠸ࡲࡍࠋࡉ࡚ࠊ⚾ࡣ᪥ᮏ࡛ࡣࡔ࠸ࡓ࠸ఱ᫬ࡃࡽ࠸࡟㉳ࡁ࡚࠸ࡿ࣮࡛࢜ࣛࣝ࢔ࢡࢭࣉࢺࡉࢀࡓࡣⰋ࠸ࡶࡢࡢࠊ࠾᜝ࡎ࡛ࡋࡻ࠺࠿㸽ࡓࡔࡋࠊࣇࣛࣥࢫ࡛ࡢࢧ࣐࣮ࢱ࢖࣒ࢆ⪃࠿ࡋ࠸ヰࠊⓎ⾲⏝ࡢࢫࣛ࢖ࢻࡸཎ✏ࡣ᪥ᮏࢆฟⓎࡋ࡚៖ࡋࡲࡍࠋࡲ࠶ࡑࢇ࡞ࡇ࡜ࡼࡾࡶࠊⓎ⾲ࡢࣉࣞࢵࢩࣕࡶࡲࡔ᏶ᡂࡉࡏࡿࡇ࡜ࡀ࡛ࡁ࡚࠸ࡲࡏࢇ࡛ࡋࡓࠋฟⓎ࣮ࡢࡏ࠸࡛ྑࡢᑠ㰯࡟ཎᅉ୙᫂ࡢ኱ࡁ࡞“࡛ࡁࡶࡢ”ᙜ᪥ࠊࣃࣜ࡬ྥ࠿࠺ JAL ࡢᶵయࢆᐇ㝿࡟┠࡟ࡍࡿ࡜࡜ୗ၁ࡢෆഃ࡟ 2 ࡘࠊᕥࡢ⯉ࡢ⿬ഃ࡟ 1 ࡘࡢ኱ࡁ࡞ཱྀ෗┿ 1 ᙜ䝅䞁䝫䝆䜴䝮䛾ᗙ㛗䛸ཱྀ㢌Ⓨ⾲⪅䠄ᕥ䛛䜙䚸El Cheikh Hussein Lama 䛥䜣䚸Rae Silver ༤ኈ䚸ฟ㞼㯞㔛Ꮚ༤ኈ䚸➹⪅䠅‫ݩ‬cf190422@meiji.ac.jp᫬㛫⏕≀Ꮫ

Vol. 26, No. 1 (2020)65ෆ⅖ࡀ࡛ࡁࠊ᪥࡟᪥࡟㢌③ࡀቑࡋ࡚࠸ࡁࡲࡋࡓࠋ࡚ࣜࣚ࠸ࡲࡍࠋᬑẁ࠿ࡽዲࢇ࡛࠾㓇ࢆ㣧ࡴ࡯࠺࡛ࡣ࡞࠸ࡢ

ࣥࡣ㣗ࡢ⾤࡜ゝࢃࢀ࡚࠸ࡿࡑ࠺࡛ࡍࡀࠊⓎ⾲ࡀ⤊ࢃࡿ࡛ࡍࡀࠊࠕ୍௙஦⤊࠼ࡓᚋࡢࣅ࣮ࣝࡀ࠺ࡲ࠸ࠖࡗ࡚ࡇ

3 ᪥┠ࡲ࡛ࡣఱࡶ࠾࠸ࡋࡃឤࡌࡽࢀࡲࡏࢇ࡛ࡋࡓࠋ

ࢀ࠿࣮㸟࡜ᛮ࠸ࡲࡋࡓࠋ

2 ᪥┠ࡲ࡛࠸ࢁࢇ࡞᪉ࡢⓎ⾲ࢆ⪺࠸࡚࠸ࡿ࡜ࠊ㉁␲

EBRS2019 ࡛ࡣ⣲ᩛ࡞ฟ఍࠸ࡀࡓࡃࡉࢇ࠶ࡾࡲࡋᛂ ⟅ ࡛ ࡋ ࡤ ࡋ ࡤ “on going” ࡜ “next issue (futureࡓࠋLeiden ኱Ꮫࡢ Meijer ◊✲ᐊࡢ Robin㸦Ph.Dplan)”࡜࠸࠺ゝⴥࢆ⪥࡟ࡋࡲࡋࡓࠋ㉁␲ᛂ⟅ࡣ༶ᛂຊStudent㸧ࡣ᫨⾜ᛶື≀࡜ⷧ᫂ⷧᬽᛶື≀ࡢ in vivoࡀồࡵࡽࢀࡿࡢ࡛ࠊࠕࡇࢀࡣ౽฼ࡔࡒࠖ࡜ᛮ࠸ࡲࡋࡓࠋMUA ࡢ࣏ࢫࢱ࣮Ⓨ⾲ࢆࡋ࡚࠸ࡲࡋࡓࠋDiscussion ࡶࡇࡢ㨱ἲࡢゝⴥ࡜ẖᬌ྇ࡁ㎸ࢇࡔ௜ࡅ↝ࡁลࡢⱥㄒ

ࡑ࠺࡛ࡍࡀࠊࠕSCN ࢆ≺ࡗ࡚㟁ᴟࢆᤄࡍࡢ㞴ࡋ࠸ࡼࢆᦠ࠼ࡿ࡜ࠊᑡࡋࡔࡅᙉࡃ࡞ࢀࡓẼࡀࡋࡲࡋࡓࠋࡑࡋࡡ㸟ࠖ࡜࠿ࠕᡂຌ⋡ࡣ࡝ࡢࡃࡽ࠸㸽ࠖ࡜࠿࠸࠺ヰ㢟࡛࡚Ⓨ⾲ᙜ᪥ࢆ㏄࠼ࡲࡋࡓࠋⓎ⾲࡛ࡣࠊ⚾ࡀᚓព࡜ࡍࡿࡶ┒ࡾୖࡀࡾࠊ⮬ศࡀࡸࡗ࡚࠸ࡿᐇ㦂ࡢⱞປࢆྠࡌ┠in vivo real-time monitoring (in vivo MUA) ࢆᙉㄪ⥺࡛ඹ᭷࡛ࡁࡿேࡀᾏࢆ㉺࠼࡚Ꮡᅾࡋ࡚࠸ࡓࡇ࡜࡟ࡋࡍࡂࡿ࡯࡝ᙉㄪࡋࠊࠕ࣎ࢫ࡟ࡇ࠺ゝ࠼ࡗ࡚ゝࢃࢀࡲឤືࡋࡲࡋࡓࠋ⚾ࡢḟ࡟Ⓨ⾲ࡋࡓ UT Southwesternࡋࡓ...ࠖ࡜ゝࡗ࡚఍ሙࢆᑠ➗࠸ࡉࡏࡿࡃࡽ࠸࡟ࡣᑡࡋ

medical center ࡢฟ㞼㯞㔛Ꮚ༤ኈࡣ㉁␲ᛂ⟅࡛ࠕࡇ࠺వ⿱ࡀ࡛ࡁ࡚࠸ࡲࡋࡓ㸦࡛ࡶᐇ㝿࡟ࡣⓎ⾲๓ࠊࡶࡢࡍ

࠸࠺ࡇ࡜ࡣࡸࡾࡲࡋࡓ࠿㸽ࠖ࡜࠸࠺ Evans Jenniferࡈࡃ㢦ࡀ㟷ࡊࡵ࡚࠸ࡓࡽࡋ࠸࡛ࡍ㸧ࠋ࡞ࢇ࡜࠿Ⓨ⾲⮬༤ኈࡢ㉁ၥ࡟ᑐࡋࠊࠕࡶ࠺඲㒊ࡸࡗࡓࠖ࡜ຊᙉࡃ㏉ࡋయࡣ⤊࠼ࡿࡇ࡜ࡀ࡛ࡁࡲࡋࡓࡀࠊ㉁␲ᛂ⟅࡛ࡣ⚾ࡢ࡚ࣜ࠸ࡓࡢࡀ༳㇟ⓗ࡛࡜࡚ࡶ࠿ࡗࡇࡼ࠿ࡗࡓ࡛ࡍࠋᮏሙࢫࢽࣥࢢຊࡀஈࡋࡍࡂ࡚ఱࢆ⪺࠿ࢀ࡚࠸ࡿ࠿ࡀࡉࡗ

ࡢ“catfight”ࢆᇉ㛫ぢࡓẼࡀࡋࡲࡋࡓࠋඛ㏙ࡋࡓ Raeࡥࡾศ࠿ࡽࡎࠊᣦᑟᩍဨࡢ୰ᮧᏕ༤ඛ⏕࡜ᗙ㛗ࡢ RaeSilver ༤ኈࡣ⚾ࡢⓎ⾲ࢆ୎ᑀ࡟ࣇ࢛࣮ࣟࡋ࡚ࡃࡔࡉ

Silver ༤ኈ࡟࠿࡞ࡾຓࡅ࡚ࡶࡽ࠸ࡲࡋࡓࠋ᭱ึ࡟㉁ၥ

ࡾࠊࡲࡓᙼዪࡢ㐣ཤࡢሗ࿌ࡣ⚾ࡀⓎ⾲ࡋࡓࢩ࣏ࣥࢪ࢘

ࡋ࡚ࡃࡔࡉࡗࡓ᪉ࡢ㉁ၥࡣࠕࡇ࠺࠸࠺ࡇ࡜ࡶࡸࡗ࡚ࡳ

࣒㢟㸸“Clock Networks in the Brain”ࡢศ㔝࡛ࡣ኱ࡁࡓࡽ࡝࠺࠿㸽㸦㸻ࡇ࠺࠸࠺ࡸࡾ࠿ࡓࡶ⚾ࡣ▱ࡗ࡚࠸ࡿ࡞ࣈࣞ࢖ࢡࢫ࣮ࣝ࡜࡞ࡾࠊ⚾ࡢ◊✲ࡢࡁࡗ࠿ࡅࡢ୍ࡘࢇࡔࡒ㸧ࠖ࡜࠸࠺ᣦᑟⓗ㉁ၥࡔࡗࡓࡽࡋ࠸ࡢ࡛ࡍࡀࠊ

㸦୍ே㸧࡜࡞ࡗ࡚࠸ࡲࡍࠋ⁫ᅾ᭱⤊᪥࡟ࡣ⾤࡛ Silver⥭ᙇࡀ MAX ࡛࠸࠿ࢇࡏࢇ⌮ゎ࡛ࡁ࡞࠸ࡢ࡛ࠕThankኵጔࡀఇ᠁ࡋ࡚࠸ࡿ࡜ࡇࢁ࡟ฟࡃࢃࡋࠊࣅ࣮ࣝࢆࡈࡕ

you for your good advice.ࠖ࡜ࡔࡅゝࡗ࡚ࠊ⤖ᯝⓗ࡟ࡑ࠺࡟࡞ࡾࡲࡋࡓࠋSilver ኵጔ࡜࠸ࢁ࠸ࢁ࡞ヰࡀ࡛ࡁ

࠶࠾ࡾ㏉ࡋࡓࡳࡓ࠸࡟࡞ࡾࠊኻ➗ࡉࢀࡲࡋࡓࠋ఍ሙ୰ࡓࡇࡢ᫬ࡢࣅ࣮ࣝࡀ⮬ศࣅ࣮ࣝྐୖ஧␒┠ࡢࣅ࣮ࣝ࡟㣕ࡧ஺࠺ⱥㄒࢆࣜ࢔ࣝࢱ࢖࣒࡛㏣࠺ࡢ࡟ᚲṚ࡛వ࡛ࡍ㸦ᬻᐃ㸦➗㸧㸧ࠋ࡜ࡶ࠶ࢀࠊࡑࢇ࡞೧኱࡞᪉࡟Ꮫ⏕⿱ࡀ↓ࡉࡍࡂ࡚ࠊ㨱ἲࡢゝⴥࡶࠕࡋ࠿ࡋ MP ࡀࡓࡾ࡞࡜࠸࠺㌟ศ࡛ࡇࡢࡼ࠺࡞య㦂ࢆࡉࡏ࡚࠸ࡓࡔ࠸ࡓࡇ࠸㸟ࠖ࡜࠸ࡗࡓ≧ἣ࡛ࡋࡓࠋ㟁Ẽ⏕⌮Ꮫ࡛ࡣᏛ࡭࡞࠿࡜ࡣࠊࡁࡗ࡜⚾ࡢ࢔࢝ࢹ࣑࢔ே⏕࡟࠾࠸࡚㈗㔜࡞ࡶࡢࡗࡓ real-time monitoring ࡛ࡋࡓࠋ࡜ࡶ࠶ࢀⓎ⾲ࢆ⤊࡜ࡋ࡚ṧࡿ࡛ࡋࡻ࠺ࠋ

࠼࡚࠿ࡽࡣ㢌③ࡀࡥࡗࡓࡾ࡜ᾘ࠼ࠊࡑࡢ᪥ࡢ IPA ࣅࣜࣚࣥࡣṔྐࡸ㢼᝟ࢆឤࡌࡿ⾤୪ࡳࡀ༳㇟ⓗ࡛ࠊẖ࣮ࣝࡀ⮬ศࣅ࣮ࣝྐୖ୍␒࠾࠸ࡋ࠿ࡗࡓࡇ࡜ࢆぬ࠼᪥ࡢኪࡈࡣࢇࡣ“ࣈࢩࣙࣥ㸦⥲⛠㸧”࡜࿧ࡤࢀࡿࣞࢫࢺ

෗┿ 2 Robin 䛾䝫䝇䝍䞊๓䛻䛶䚹᫬㛫⏕≀Ꮫ
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Vol. 26, No. 1 (2020)࡛ࣛࣥࣜࣚࣥࡢ㒓ᅵᩱ⌮ࢆᴦࡋࡳࡲࡋࡓࠋ⏕ά㠃࡛ࡣࠊ᭱ᚋ࡟㔜ࡡ࡚࡟࡞ࡾࡲࡍࡀࠊ௒ᅇࡇࡢࡼ࠺࡞㈗㔜࡞ࣜࣚࣥࡣ㸦≉࡟⚾ࡓࡕࡢᐟࡲࢃࡾ㸧ࡣࢫ࣮ࣃ࣮ࡸࢥࣥ

య㦂ࢆ኱Ꮫ㝔 1 ᖺ⏕࡜࠸࠺ⱝࡉ࡛࡛ࡁࡓࡇ࡜ࡣ࡜࡚

ࣅࢽࡀ࡝ࡇ࡟࡛ࡶ࠶ࡿࢃࡅ࡛ࡣ࡞ࡃ᪥᭙᪥ࡣࡕࡷࢇࡶࣛࢵ࣮࢟࡞ࡇ࡜ࡔ࡜ᛮ࠸ࡲࡍࠋ◊✲㸦ᐇ㦂㸧ࡣᚲࡎ࡜ఇࡴ♫఍ࡔࡗࡓࡢ࡛ࠊAirbnb ࡛ᐟࢆྲྀࡗ࡚࠸ࡓ⚾ࡋࡶᴦࡋ࠸ࡇ࡜ࡤ࠿ࡾ࡛ࡣ࡞࠸࡛ࡍࡀࠊࡇ࠺࠸࠺ᶵ఍ࡓࡕࡣᑡࡋ୙౽࡟ឤࡌࡲࡋࡓࠋࡋ࠿ࡋࠊࡑࢀ࡜ྠ᫬࡟ࡀ୍ࡘࡢࢦ࣮ࣝ࡟タᐃࡉࢀ࡚࠸ࡿ࡜◊✲ࡢࣔࢳ࣮࣋᪥ᮏࡀ౽฼ࡍࡂࡿࡢࡔ࡜ࡶᛮ࠸ࡲࡋࡓࠋⰋ࠸ࡇ࡜ࡢ⿬

ࢩࣙࣥ࡟ࡶ⧅ࡀࡾࡲࡍࠋᏛ఍ᚋࠊ⚾ࡢᚋ㍮ࡓࡕ࡟ࡣࠊ

࡟ࡣᝏ࠸ࡇ࡜ࡀ࠶ࡾ㏫ࡶࡲࡓ↛ࡾ࡞ࡢࡔ࡜ࠊwork ࡜ᑠࡉ࡞ࢦ࣮ࣝࢆタᐃࡋ୍ࡘࡎࡘࢡࣜ࢔ࡋ࡚࠸ࡃࡇ࡜life ࡢࣂࣛࣥࢫࢆ⪃࠼ࡉࡏࡽࢀࡲࡋࡓࠋࡓࡔࠊ࢛࢘ࢵ࡛ࠊࣔࢳ࣮࣋ࢩࣙࣥࢆಖࡘࡇ࡜ࢆ࢔ࢻࣂ࢖ࢫࡋࡲࡋࡓࠋࢩࣗࣞࢵࢺࡔࡅࡣ඲ୡ⏺࡛ᬑཬࡋ࡚࡯ࡋ࠸࡜ᛮ࠸ࡲࡑࢀ࡛ࡶ࡝࠺ࡋ࡚ࡶ᎘࡟࡞ࡗࡓ࡜ࡁࡣࠊ࠾࠸ࡋ࠸ࡶࡢࡋࡓࠋⰋࡉࡋ࠿࡞࠸࡛ࡍࠋ㸦࡜ᛮ࠸ࡲࡍࠋ㸧ࡓࡃࡉࢇ㣗࡭ࡿ࠿ࠊࡼࡃᐷࡲࡋࡻ࠺㸟෗┿ 3 䠄ᕥୖ䠅 Silver ኵጔ䛸୰ᮧᏕ༤ඛ⏕䛸➹⪅䛾4 䝅䝵䝑䝖䚹䠄ྑୖ䠅ถ᪕㛛๓䛻䛶䚹ྠᮇ䛾ᮡᒣ䛸➹⪅䚹䠄ᕥୗ䠅䝤䝅䝵䞁䜔䝤䝔䜱䝑䜽䛜❧䛱୪䜆䝸䝶䞁ᪧᕷ⾤䚹᫬㛫⏕≀Ꮫ

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