Royal jelly dose not prevent boneloss but improves bone strengthin ovariectomized rats
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D.W. 610ml/kg b.w.7

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(g)
240
230

*220

*210
200

Sham

190

OVX

180

OVX+RJ

170
160
1500w

2w

4w

6w

8w

10w

12w

*P < 0.05 vs. Sham
(ANOVA with Tukey’s HSD test)

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(g)
0.45


(%)

P<0.01
P<0.01

0.4

0.2

P<0.01
P<0.01
N.S.

N.S.

0.35

0.15

0.3
0.25

0.1

0.2
0.15

0.05

0.1
0.05

00shamOVXOVX+RJsham

OVXOVX+RJANOVA with Tukey’s HSD test

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(g/cm2)

P<0.01

0.25

P<0.01

N.S.

0.2
0.15
0.1
0.05
0Baseline

Sham

OVX

OVX+RJANCOVA with Tukey’s HSD test

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800700P<0.01
P<0.01
N.S.

600
500
400
300(mg/cm3)
350
300


P<0.01
P<0.01
N.S.

250
200
150(mg/cm3)
1400
1350

N.S.
N.S.

1250

100

501150001100Ba
selineSh
am
OO VX
VX+
RJ

200

1200

Ba
selin
eSh
am
OO VX
VX+
RJ

N.S

1300

100

Ba
seline
Sh
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O
O VX
V
X+RJ



ANCOVA with Tukey’s HSD test

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""Baseline

ShamOVXOVX+RJ(%)

28.5 ± 1.2

28.8 ± 1.3

15.0 ± 0.9 †16.0 ± 2.2 †  (μm)55.4 ± 1.0

62.0 ± 1.5

64.2 ± 2.2

67.5 ± 3.3

  (/mm)

5.15 ± 0.20

4.63 ± 0.17

2.34 ± 0.12 †2.33 ± 0.22 † (%)

4.09 ± 0.44

2.03 ± 0.23

4.36 ± 0.61 †5.09 ± 0.58 * (%)

26.2 ± 2.4

15.7 ± 1.432.8 ± 2.5 †38.0 ± 1.9 † (%)
%)

13.39 ± 2.21
7.32 ± 0.60

3.97 ± 0.54
5.89 ± 0.49

7.34 ± 1.23
5.61 ± 0.47

9.38 ± 2.54
6.78 ± 0.53

 (%)

3.65 ± 0.44

2.20 ± 0.23

3.10 ± 0.26

2.73 ± 0.58

*P < 0.05, †P < 0.01 compared with Sham
(Sham vs. OVX vs. OVX+RJ, ANCOVA with Tukey’s HSD test).

Baseline

ShamOVXOVX+RJ

33.1 ± 1.5

17.7 ± 2.1

31.9 ± 2.4 †30.5 ± 2.6 †2.50 ± 0.17

1.27 ± 0.05

1.45 ± 0.10

1.62 ± 0.08 *0.302 ± 0.023

0.081 ± 0.010

0.173 ± 0.023 *0.184 ± 0.024 * 
 (%)
(μm/day)(mm3/mm2/year)(/year)

1097 ± 97
261 ± 35536 ± 73 *548 ± 68 **P < 0.05, †P < 0.01 0.01 compared with Sham
(Sham vs. OVX vs. OVX+RJ, ANCOVA with Tukey’s HSD test).

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N.S.

P<0.05(W)
120

N.S.
N.S.

N.S.
(N.mm)
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N.S

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450
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N.S.
N.S.

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0.25
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N.S.

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0.25

N.S.

0.2

0.15

0.15

0.1

0.1

0.05

0.05

00shamOVXOVX+RJ

P=0.01sham

P=0.01OVXOVX+RJ

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