5 reasons that IPD is selectedIsopentyldiol (IPD)
Multi-functional Moisturizer
INCI Name
Isopentyldiol
Applications
Skin care
Skin lotion, Moisturizing cream, Make up remover, Facial wash, Face mask, Body wash, Liquid soap, Self tanning &Sun care,,,,Hair care
Shampoo, Conditioner, Treatment, Styling, Color treatment,,,,Color Cosmetics
Lipstick, Foundation, Eye shadow,,,,
Others
Wet wipe, Baby care, Bath oil, Oral care, Fragrance,,,,3/22/2024

25 reasons that IPD is selected
Smooth and Silky feeling / No irritation

Cleansing

Hair repair

Preservative boost

Solubilizing

Gently cleans makeup,sebum, keratin plugand lead healthy skinRepair hair and leadhealthy hair

Reduce preservatives
and lead healthy skin

Achieve Ethanol-freeand lead healthy skin
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Cleansing power

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4

Conclusion：IPD can clean pores gently and thoroughly
Point

１

High Cleansing power (keratin plug, sebum, makeup）

２

Smooth feeling３

No irritation

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Improves the cleaning power of keratin plugs more than twice as much as
conventional products
Keratin plug cleansing test of cleansing gel

Appearance

Cleansing rate
(Relative value with No polyol)

No polyol

IPD12%

Dipropylene
glycol 12%

Glycerin 12%

Butylene glycol
12%32.521.5
10.50No polyol

IPD 12%Butyleneglycol12%

Dipropylene
glycol12%Glycerin
12%<Test>
Red-colored artificial keratin plugs were packed in silicone plates and washedwith each cleansing gel.
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Make Smooth feelingSensory evaluation of each polyol aqueous solution
Cleansing power(Foundation)

Softness

Smoothness

10% IPD

87654321010% BG
10% DPG
Cleansingpower(lipstick)Freshness

Low←1～10→High
Tested by Irfaq<Test>
Foundation and lipstick were applied, and cleansed with each polyol solution
evaluating for their usability.
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No irritation
Stinging test for sensitive skin

Skin irritation index

1.3

1.2

No irritation
1.1

1.0
IPD

ButyleneglycolPropylene
glycolGlycerin<Test>
Stinging tests of each polyol 50% aqueous solution were performed on 10 subjects
with sensitive skin.
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IPD can be used to develop safe and highly functional cleansers

Cleansers that claim to clean pores (cleansings, facial washes,shampoos...)

Sensitive skin and baby care cleansers that claim to be moisturizing
and gentle on the skinSmooth feeling cleansers
etc.

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Hair repair

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Conclusion：IPD can repair hair and make smooth feeling
Point

１

Smooth feeling

２

Hair repair effect

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Make Smooth feelingSensory evaluation of hair cream

なめらかさ UP !!

Smoothness
5Glycerin 3.0%

4

IPD 3.0%3

Butylene glycol 3.0%

2No polyol

1Anti-frizz0

Spreadability during
application

Low←1～5→HighMoisture<Test>Evaluated the performance of each hair cream

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Repair cuticle of hair in combination with sugars
Appearance observation with SEM
Damaged Hair (Before)

After treated with the solution ofIPD 5% & Sorbitol 5%

Repair cuticle

Tested by Irfaq<Test>- The damaged hair soaked in the water solution of 5% IPD & 5% Sorbitol for 30 min.
- After wash and dried, compared the appearance of “before” & “after” with SEM
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Make hair smooth in combination with sugars
Ring Drop Test
Non treated
0Dipropylene
Butylene
IPD 5%+glycol 5% + glycol 5% +Sorbitol 5% Sorbitol 5%Sorbitol 5%
solutionsolutionsolution

Propylene
glycol 5% +Sorbitol 5%
solution

1Fall distance (cm)Smooth234567

Tested by Irfaq<Test>- The damaged hairs were soaked in each water solution.
- After washed and dried, the hairs were clipped & made the rings slide along with the hairs.
- Measured the fall distances which mean “how the hair was treated smooth” (n=5)
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IPD provides comparable conditioning effect to Silicone
Measurement of contact angle of water on hair
1.6

1.2
Contact angle(relative value to damaged hair）

1.4

1.0
0.8
0.6
0.4
0.2
0.0
DamagedRx2
hair
Slicone
5.8%

Rx1
Rx1
Rx1
Rx1
Rx1
Healthy
IPD 2.4％ BG 2.4％ PG 2.4％ Glycerin DPG 2.4％
hair
2.4％

Treatment’s formulation
Ingredients
Steartrimonium Chloride
Behentrimonium Chloride
Cetyl Alcohol
Polyol x
Trehalose
Cetyl Ethylhexanoate
Olea Europaea (Olive) Fruit Oil
Octyldodecanol
Pentylene glycol
Ethylhexylglycerin
Phenoxyethanol
Amodimethicone
Dimethicone（10cSt, high polymerization）Dimethicone （1000cSt）
Lactic Acid
Water

Rx1
2.6
1.2
3.6
2.4
2.4
3.0
1.2
0.8
1.2
0.3
0.5
-Rx2
2.6
1.2
3.6
3.0
1.2
0.8
1.2
0.3
0.5
0.8

pH3.5
to 100

4.0
1.0
pH3.5
to 100<Test>
Bleached hair bundles were treated with each treatment for 2 minutes, and 1 µL drops of water were dropped onto the dried hair and the contact
angle was measured.（n=10）
2024年3月22日

15IPD can be used to develop highly functional hair care products

Smooth feeling hair careHair care that claim to repair hair

Silicone-free hair careetc.

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Preservative boost

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Conclusion：IPD helps to make Paraben-free and Preservative-free cosmetics
Point

１

Preservative boost effect２

No irritation

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Boost preservative effect when used in combination with phenoxyethanol, acommonly used paraben alternative
Inhibits bacterial growth better thanother polyols

Challenge test of Lotion including IPD & Phenoxyethanol
Microbe mixture 1

Microbe mixture 2

Microbe mixture 3

1.E+07107

1.E+07107

1.E+07
10７

Propanediol 5%, Phenoxyethanol 0.3%

1.E+06

1.E+06

1.E+06

IPD5%, Phenoxyethanol 0.3%

1.E+05

1.E+05

1.E+05Butylene glycol 5%, Phenoxyethanol 0.3%

1.E+04(n/g)

1.E+04(n/g)

1.E+04(n/g)

Propylene glycol 5%, Phenoxyethanol 0.3%

1.E+03

1.E+03

1.E+03

1.E+02

1.E+02

1.E+02

1.E+0110

10
1.E+01

1.E+01
10071421

Days (day)0714

Days (day)21

Dipropylene glycol 5%, Phenoxyethanol 0.3%
Phenoxyethanol 0.3%

071421

Days (day)<Test>Do the challenge test of each lotion.
Microbe mixture 1; bacteria
Mixture of Escherichia coli, Pseudomonas aeruginosa, and Staphylococcus aureus
Microbe mixture 2; Kitchen draining filter liquid
Highly detected microbe: Enterobacter, Citrobacter, Serratia, Klebsiella, Pseudomonas, Acinetobacter, Bacillus and Candida
Microbe mixture 3; fungus
Mixture of Aspergillus brasiliensis, Candida albicans, Penicillium citrinum, and Aureobasidium pullulans

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Boost preservative effect when used in combination with pentylene glycol,
a commonly used preservative alternative
Challenge test of Lotion including IPD & Pentylene glycol
Microbe mixture 1

Microbe mixture 2

1.E+06

1.E+06

1.E+05

1.E+05

1.E+04(n/g)

1.E+04

1.E+03

1.E+03

1.E+02

1.E+0210
1.E+0110
1.E+01

1.E+06
106
IPD 5%, Pentylene glycol 2.0%

071421

Days (day)Pentylene glycol 3.5%(n/g)

1.E+07
107

(n/g)

107
1.E+07Microbe mixture 3

1.E+05

Pentylene glycol 2.0%104
1.E+040714

Days (day)

21071421

Days (day)<Test>Do the challenge test of each lotion.
Microbe mixture 1; bacteria
Mixture of Escherichia coli, Pseudomonas aeruginosa, and Staphylococcus aureus
Microbe mixture 2; Kitchen draining filter liquid
Highly detected microbe: Enterobacter, Citrobacter, Serratia, Klebsiella, Pseudomonas, Acinetobacter, Bacillus and Candida
Microbe mixture 3; fungus
Mixture of Aspergillus brasiliensis, Candida albicans, Penicillium citrinum, and Aureobasidium pullulans

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IPD can be used to develop Paraben-free and preservative-free cosmetics

Paraben-free / Preservative-free skin care, hair cairSensitive skin and baby care products for high safetyLarge capacity facial masks for easy secondary contaminationetc.

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Solubilizing

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Conclusion： IPD helps to make Ethanol-free cosmetics
Point

１

High solubilizing power

２

No irritation

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Solubilize oil-soluble ingredients into water
Solubilization test of Icaridin into waterEthanol

IPD

BG

DPG

Formulation
Ingredient
Polyol X
PEG-40 Hydrogenated
Castor OilIcaridin
Water

wt%
30.0
3.0
15.0
To 100The insect repellent ingredient Icaridin, which was conventionally dissolved inethanol, was solubilized in water
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Solubilize various oil-soluble ingredients
Solubilizing test of oil-soluble ingredients into water

Formulation

Oil-soluble
ingredients

No polyol

IPD

Butylene glycol

Dipropylene
glycolTocopherol

Clouded

Clear

CloudedCloudedMenthol

Clouded

Clear

Clear

CloudedIngredient
Polyol X
PEG-60 Hydrogenated Caster Oil
Oil based ingredient YWaterwt%
5.0
1.00.05
To 100Appearance of tocopherol mixed
No polyol

IPD

Butylene glycol

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IPD can be used to develop Ethanol-free cosmetics

Ethanol-free sensitive skin and baby care products

Ethanol-free insect repellent for childrenEthanol-free perfumeetc.

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